A network of cross-linked hydrophilic macromolecules used in biomedical applications.
Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.
Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.
Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.
Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.
A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.
Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.
The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.
A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.
A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food adjuvant, plasma substitute, hemostatic, suspending agent in pharmaceutical preparations, and in the manufacturing of capsules and suppositories.
Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.
A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)
Hydrophilic contact lenses worn for an extended period or permanently.
A biocompatible, hydrophilic, inert gel that is permeable to tissue fluids. It is used as an embedding medium for microscopy, as a coating for implants and prostheses, for contact lenses, as microspheres in adsorption research, etc.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Colorless, odorless crystals that are used extensively in research laboratories for the preparation of polyacrylamide gels for electrophoresis and in organic synthesis, and polymerization. Some of its polymers are used in sewage and wastewater treatment, permanent press fabrics, and as soil conditioning agents.
Microbial, plant, or animal cells which are immobilized by attachment to solid structures, usually a column matrix. A common use of immobilized cells is in biotechnology for the bioconversion of a substrate to a particular product. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.
The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.
Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
Numerical expression indicating the measure of stiffness in a material. It is defined by the ratio of stress in a unit area of substance to the resulting deformation (strain). This allows the behavior of a material under load (such as bone) to be calculated.
Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.
The properties and processes of materials that affect their behavior under force.
Dressings comprised of a self-adhesive matrix to which hydrophilic absorbent particles are embedded. The particles consist of CELLULOSE derivatives; calcium ALGINATES; PECTINS; or GELS. The utility is based on providing a moist environment for WOUND HEALING.
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
Methods for maintaining or growing CELLS in vitro.
Submicron-sized fibers with diameters typically between 50 and 500 nanometers. The very small dimension of these fibers can generate a high surface area to volume ratio, which makes them potential candidates for various biomedical and other applications.
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
Materials fabricated by BIOMIMETICS techniques, i.e., based on natural processes found in biological systems.
Sterile solutions used to clean and disinfect contact lenses.
Introduction of substances into the body using a needle and syringe.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
Polymers of silicone that are formed by crosslinking and treatment with amorphous silica to increase strength. They have properties similar to vulcanized natural rubber, in that they stretch under tension, retract rapidly, and fully recover to their original dimensions upon release. They are used in the encapsulation of surgical membranes and implants.
Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.
Bone-marrow-derived, non-hematopoietic cells that support HEMATOPOETIC STEM CELLS. They have also been isolated from other organs and tissues such as UMBILICAL CORD BLOOD, umbilical vein subendothelium, and WHARTON JELLY. These cells are considered to be a source of multipotent stem cells because they include subpopulations of mesenchymal stem cells.
Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
The resistance that a gaseous or liquid system offers to flow when it is subjected to shear stress. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The sodium salt of BENZOIC ACID. It is used as an antifungal preservative in pharmaceutical preparations and foods. It may also be used as a test for liver function.
Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.
Process by which unwanted microbial, plant or animal materials or organisms accumulate on man-made surfaces.
An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS.
Relating to the size of solids.
Artificial substitutes for body parts and materials inserted into organisms during experimental studies.
Material used for wrapping or binding any part of the body.
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
Characteristics or attributes of the outer boundaries of objects, including molecules.
Biological activities and functions of the SKIN.
A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.
A technique for maintaining or growing TISSUE in vitro, usually by DIFFUSION, perifusion, or PERFUSION. The tissue is cultured directly after removal from the host without being dispersed for cell culture.

Lysozyme sorption in hydrogel contact lenses. (1/453)

PURPOSE: To examine the processes involved in formation of protein deposits on hydrogel contact lenses. METHODS: The adsorption and/or penetration of lysozyme on or into three types of contact lenses, etafilcon A, vifilcon A, and tefilcon, were investigated in vitro using a radiolabel-tracer technique, x-ray photoelectron spectroscopy, and laser scanning confocal microscopy. RESULTS: Binding of lysozyme to high-water-content, ionic contact lenses (etafilcon A and vifilcon A) was dominated by a penetration process. The extent of this penetration was a function of charge density of the lenses, so that there was a higher degree of penetration of lysozyme in etafilcon A than in vifilcon A lenses. In contrast, the binding of lysozyme to tefilcon lenses was a surface adsorption process. The adsorption and desorption kinetics showed similar trends to those found in human serum albumin (HSA) adsorption on lens surfaces. However, the extent of lysozyme adsorption on tefilcon is much higher than HSA adsorption, probably because of the self-association of lysozyme on the tefilcon lens surface. Furthermore, either penetration or adsorption of lysozyme involved reversible and irreversible processes and were both time dependent. CONCLUSIONS: Binding of lysozyme to hydrogel lenses involves surface adsorption or matrix penetration. These processes may be reversible or irreversible. The properties of the lens materials, such as charge density (ionicity) and porosity (water content) of the lenses, determine the type and rates of these processes.  (+info)

Sympathetic swelling response of the control eye to soft lenses in the other eye. (2/453)

PURPOSE: To compare central corneal swelling and light scatter after 8 hours of sleep in eyes wearing high- and low-Dk hydrogel lenses and to the contralateral control eyes. METHODS: Twenty neophyte subjects wore a Lotrafilcon A (Dk, 140; Ciba Vision, Duluth GA) silicone hydrogel lens and an Etafilcon A (Dk, 18; Acuvue; Vistakon, Jacksonville, FL) 58% water content hydrogel lens of similar center thickness in random order in the right eye only, for overnight 8-hour periods. The contralateral nonwearing left eyes served as controls. Central corneal thickness was measured using an optical pachometer and light scatter using a Van den Berg stray-light meter before lens insertion, after lens removal on waking, and every 20 minutes for the next 3 hours. RESULTS: Central corneal swelling induced by the Etafilcon A lens on eye opening was significantly higher than with the Lotrafilcon A lens (8.66%+/-2.84% versus 2.71%+/-1.91%; P<0.00001). Light scatter induced by the Etafilcon A lens on eye opening was significantly higher than with the Lotrafilcon A lens (46.09+/-5.62 versus 42.78+/-6.07 Van den Berg units, P = 0.0078). The swelling of the control eyes paired with the Etafilcon A lens-wearing eyes was also slightly but significantly higher than that of the control eyes paired with the Lotrafilcon A lens-wearing eyes (2.34%+/-1.26% versus 1.44%+/-0.91%; P = 0.0002). Light-scatter measurements were not significantly different between control sets of eyes but showed the same trend. CONCLUSIONS: In neophyte subjects, corneal swelling of the contralateral control eyes appears to be influenced by the swelling of the fellow lens-wearing eyes-that is, the swelling of the contralateral control eye was significantly lower when there was less swelling of the fellow eye wearing the high-Dk lens. Although there was no statistically significant difference in light-scatter measurements between the control sets of eyes, a trend similar to the corneal swelling results was observed, which could be used to support the suggestion that this may be a sympathetic physiological response rather than an unusual sampling coincidence.  (+info)

Orally administered, insulin-loaded amidated pectin hydrogel beads sustain plasma concentrations of insulin in streptozotocin-diabetic rats. (3/453)

We report successful oral administration of insulin entrapped in amidated pectin hydrogel beads in streptozotocin (STZ)-diabetic rats, with a concomitant reduction in plasma glucose concentration. The pectin-insulin (PI) beads were prepared by the gelation of humilin-pectin solutions in the presence of calcium. Separate groups of STZ-diabetic rats were orally administered two PI beads (30 micrograms insulin) once or twice daily or three beads (46 micrograms) once daily for 2 weeks. Control non-diabetic and STZ-diabetic rats were orally administered pectin hydrogel drug-free beads. By comparison with control non-diabetic rats, untreated STZ-diabetic rats exhibited significantly low plasma insulin concentration (0.32+/-0. 03 ng/ml, n=6, compared with 2.60+/-0.44 ng/ml in controls, n=6) and increased plasma glucose concentrations (25.84+/-1.44 mmol/l compared with 10.72+/- 0.52 mmol/l in controls). Administration of two PI beads twice daily (60 micrograms active insulin) or three beads (46 micrograms) once a day to STZ-diabetic rats increased plasma insulin concentrations (0.89+/-0.09 ng/ml and 1.85+/- 0.26 ng/ml, respectively), with a concomitant reduction in plasma glucose concentration (15.45+/-1.63 mmol/l and 10.56+/-0.26 mmol/l, respectively). However, a single dose of PI beads (30 micrograms) did not affect plasma insulin concentrations, although plasma glucose concentrations (17.82+/-2.98 mmol/l) were significantly reduced compared with those in untreated STZ-diabetic rats. Pharmacokinetic parameters in STZ-diabetic rats show that the orally administered PI beads (30 micrograms insulin) were more effective in sustaining plasma insulin concentrations than was s.c. insulin (30 micrograms). The data from this study suggest that this insulin-loaded amidated pectin hydrogel bead formulation not only produces sustained release of insulin, but may also reduce plasma glucose concentration in diabetes mellitus.  (+info)

Biomechanical and histological evaluation of hydrogel implants in articular cartilage. (4/453)

We evaluated the mechanical behavior of the repaired surfaces of defective articular cartilage in the intercondylar region of the rat femur after a hydrogel graft implant. The results were compared to those for the adjacent normal articular cartilage and for control surfaces where the defects remained empty. Hydrogel synthesized by blending poly(2-hydroxyethyl methacrylate) and poly(methyl methacrylate-co-acrylic acid) was implanted in male Wistar rats. The animals were divided into five groups with postoperative follow-up periods of 3, 5, 8, 12 and 16 weeks. Indentation tests were performed on the neoformed surfaces in the knee joint (with or without a hydrogel implant) and on adjacent articular cartilage in order to assess the mechanical properties of the newly formed surface. Kruskal-Wallis analysis indicated that the mechanical behavior of the neoformed surfaces was significantly different from that of normal cartilage. Histological analysis of the repaired defects showed that the hydrogel implant filled the defect with no signs of inflammation as it was well anchored to the surrounding tissues, resulting in a newly formed articular surface. In the case of empty control defects, osseous tissue grew inside the defects and fibrous tissue formed on the articular surface of the defects. The repaired surface of the hydrogel implant was more compliant than normal articular cartilage throughout the 16 weeks following the operation, whereas the fibrous tissue that formed postoperatively over the empty defect was stiffer than normal articular cartilage after 5 weeks. This stiffness started to decrease 16 weeks after the operation, probably due to tissue degeneration. Thus, from the biomechanical and histological point of view, the hydrogel implant improved the articular surface repair.  (+info)

Evaluation of properties microcrystalline chitosan as a drug carrier. Part 1. In vitro release of diclofenac from mictocrystalline chitosan hydrogel. (5/453)

The influence of microcrystalline chitosan hydrogel, alone (MCCh) as well as in combination with methylcellulose (MC) or Carbopol (CP), on the release of diclofenac free acid (DA) and its salt (DS) was studied in vitro. Commercial Olfen gel (Mepha Ltd., Switzerland) was applied as a reference preparation. The influence of hydrophilizing agents (1,2-propylene glycol and glycerol) and methycellulose hydrogel on the rheological properties of the vehicle and on the release of drug from modified MCCh hydrogel was studied. The quantity of the released substance was determined by UV-spectroscopy. The results confirmed that release was dependent on the chemical character of the drug and on the type of vehicle. The process of diclofenac release from MCCh hydrogels as well as from Carbopol hydrogels runs in two phases. The first phase is characterised by rapid release whereas in the second phase the release is much slower. The most suitable basis for diclofenac is microcrystalline chitosan hydrogel with addition glycerol, 1,2-propylene glycol, and methylcellulose hydrogel.  (+info)

Improvement of transdermal permeation of captopril by iontophoresis. (6/453)

AIM: The feasibility of iontophoresis on the transdermal delivery of captopril was studied. METHODS: Iontophoresis was employed for enhancing transdermal transport of captopril through rat skin in vitro and in vivo. RESULTS: It was demonstrated that the iontophoresis-induced flux of captopril was affected by various factors such as pH, ionic concentration, and the concentration of captopril in donor compartments as well as the applied electric current intensity. Electric current could induce several-fold increase in captopril flux with hydrogel. Skin permeation study in vivo in rats demonstrated that iontophoresis could effectively promote the transdermal transport of captopril without significant skin irritation. Captopril concentration in plasma reached plateau (approximately 0.9 microgram/mL) at 1 h after current application and was maintained at the same level during the experiment. On the contrary, captopril could not be detected in plasma when the current was not applied. No obvious skin irritation was observed after 9-h continuous iontophoresis. CONCLUSION: Transdermal delivery of captopril can be effectively improved by iontopophoresis.  (+info)

Imaging of hydrogel episcleral buckle fragmentation as a late complication after retinal reattachment surgery. (7/453)

Hydrogel encircling bands were introduced in the early 1980s as a product that was superior to bands composed of silicone rubber or silicone sponge for the surgical treatment of retinal detachment. Late complications consisting of orbital swelling and diplopia requiring band removal began to be reported in the early 1990s. Pathologic studies of these expanded fragments of hydrogel material after removal showed in vivo hydrolysis with foreign body reaction and dystrophic calcification. We report the imaging findings in five patients in whom this late complication developed. Hydrogel fragmentation has a characteristic imaging appearance consisting of a circumferential orbital mass associated with rim enhancement. This appearance should prompt inquiries regarding previous scleral buckle procedures with hydrogel bands. Familiarity with this appearance will avoid misinterpretation and unwarranted biopsy before band removal.  (+info)

Cell traction forces on soft biomaterials. I. Microrheology of type I collagen gels. (8/453)

A laser-trap microrheometry technique was used to determine the local shear moduli of Type I collagen gels. Embedded 2.1 microm polystyrene latex particles were displaced 10-100 nm using a near-infrared laser trap with a trap constant of 0.0001 N/m. The trap was oscillated transversely +/- 200 nm using a refractive glass plate mounted on a galvanometric scanner. The displacement of the microspheres was in phase with the movement of the laser trap at frequencies less than 1 rad/s, indicating that at least locally, the gels behaved as elastic media. The local shear modulus was measured at various positions throughout the gel, and, for gels at 2.3 mg/mL and 37 degrees C, values ranged from G = 3 to 80 Pa. The average shear modulus G = 55 Pa, which compares well with measurements from parallel plate rheometry.  (+info)

A method of fabricating hydrogel particles within liposomes, which entails: a) encapsulating an effective amount of each of one or more hydrogel substances and one or more release agents in liposomes in a liquid medium, b) removing any unencapsulated hydrogel substances and release agents from the liquid medium, c) adding initiator to the liquid medium and into the liposomes, thereby initiating reaction of the one or more hydrogel substances, whereby hydrogel particles are formed in the liposomes, and d) removing any extra-liposomal initiator from the medium.
TY - JOUR. T1 - Enzyme-triggered cell attachment to hydrogel surfaces. AU - Todd, Simon J.. AU - Farrar, David. AU - Gough, Julie E.. AU - Ulijn, Rein V.. PY - 2007. Y1 - 2007. N2 - We describe enzyme-triggered activation of cell adhesion ligands tethered to a hydrogel surface to direct the attachment of osteoblast cells on demand.. AB - We describe enzyme-triggered activation of cell adhesion ligands tethered to a hydrogel surface to direct the attachment of osteoblast cells on demand.. KW - enzyme-triggered. KW - cell attachment KW - hydrogel surfaces. U2 - 10.1039/b618256a. DO - 10.1039/b618256a. M3 - Article. VL - 3. SP - 547. EP - 550. JO - Soft Matter. JF - Soft Matter. SN - 1744-683X. IS - 5. ER - ...
Development and optimization of a dual-photoinitiator, emulsion-based technique for rapid generation of cell-laden hydrogel microspheres.
Emerging medical technologies for effective and lasting repair of articular cartilage include delivery of cells or cell-seeded scaffolds to a defect site to initiate de novo tissue regeneration. Biocompatible scaffolds assist in providing a template for cell distribution and extracellular matrix accumulation in a three-dimensional geometry. In these studies, a self-assembling peptide hydrogel is evaluated as a potential scaffold for cartilage repair using a model bovine cell source. A seeding technique is developed for 3-D encapsulation of chondrocytes in a peptide hydrogel. The chondrocyte-seeded peptide hydrogel was then evaluated cellular activities in vitro under standard culture conditions and also when subjected to dynamic compression. During 4 weeks of culture in vitro, chondrocytes seeded within the peptide hydrogel retained their morphology and developed a cartilage-like ECM rich in proteoglycans and type II collagen, indicative of a stable chondrocyte phenotype. Time dependent ...
Hydrogel particles, also known as microgels, consist of cross-linked three-dimensional water-soluble polymer networks. They play an essential role in loading and delivering active ingredients in medicine, cosmetics, and foods. Despite their excellent biocompatibility as well as structural diversity, much wider applications are limited due mainly to their intrinsically loose network nature. This study introduces a practical and straightforward method that enables fabrication of hydrogel microparticles layered with a mechanically robust hybrid thin shell. Basically highly monodisperse hydrogel microparticles were produced in microcapillary devices. Then, their surface was coated with alternate polyelectrolyte layers through the layer-by-layer deposition. Finally a thin silica layer was again formed by reduction of silicate on the amino-functionalized polyelectrolyte layer. We have figured out that these hybrid hydrogel microparticles showed controlled loading and releasing behaviors for ...
Synthetic hydrogel scaffold is an effective vehicle for delivery of INFUSE (rhBMP2) to critical-sized calvaria bone defects in rats Journal Article ...
0118] In an aspect of this embodiment, a hydrogel formulation comprises a gel phase including hydrogel particles having a particle size from about 5 μm2 to about 1000 μm2 in cross-sectional area. In aspects of this embodiment, a hydrogel formulation comprises a gel phase including hydrogel particles having a mean particle size of, e.g., about 5 μm2, about 10 μm2, about 15 μm2, about 20 μm2, about 25 μm2, about 30 μm2, about 35 μm2, about 40 μm2, about 45 μm2, about 50 μm2, about 60 μm2, about 70 μm2, about 80 μm2, about 90 μm2, about 100 μm2, about 200 μm2, about 300 μm2, about 400 μm2, about 500 μm2, about 600 μm2, about 700 μm2, about 800 μm2, about 900 μm2, or about 1000 μm2 in cross-sectional area. In other aspects of the embodiment, a hydrogel formulation comprises a gel phase including hydrogel particles having a mean particle size of, e.g., at least 5 μm2, at least 10 μm2, at least 15 μm2, at least 20 μm2, at least 25 μm2, at least 30 μm2, at least 35 μm2, ...
The combination of hydrogel and nitrogen may favor the expression of grain productivity of wheat. The goal of the study was to analyze the nitrogen utilization efficiency in wheat through the hydrogel biopolymer, defining the optimal dose of hydrogel and nitrogen combination at the maximum grain productivity, in succession systems of high and reduced N-residual release. The study was carried out in 2014 and 2015, in randomized block design with four replicates in a 4 x 4 factorial, for hydrogel doses (0, 30, 60 and 120 kg ha-1), added in the furrow along the seed and fertilizer-N doses (0, 30, 60 and 120 kg ha-1), applied in the stage of third leaf expanded, respectively, in the soy/wheat and corn/wheat systems. The hydrogel biopolymer increases the efficiency of nitrogen use in grain productivity of wheat in succession systems. The ideal combination of hydrogel and nitrogen at the maximum grain productivity is 58 and 93 kg ha-1, respectively, in the soybean/wheat systems and 44 and 115 kg ha-1, ...
This synthetic hydrogel can be used to culture human intestinal organoids and may one day help provide a treatment for intestinal conditions.
Congratulations to Jiwei Cui et al from the University of Melbourne and the Laboratory for Mechanics of Materials and Nanostructureswho recently published Super soft hydrogel particles with tunable elasticity in a microfluidic blood capillary model in Advanced Materials. The paper explores super-soft PEG hydrogel particles with tunable elasticity which are prepared via a mesoporous silica templating method. The deformability behavior of these particles, in a microfluidic blood capillary model, can be tailored to be similar to that of human red blood cells. These results provide a new platform for the design and development of soft hydrogel particles for investigating bio-nano interactions. (see figure 1) Congratulations to MCN Staff Member, Fatima Eftekhari and Technology Fellows Wenlong Cheng and Qiaoliang Bao from Monash University who recently published Giant Plasmene Nanosheets, Nanoribbons, and Origami in ACS Nano. The paper introduces Plasmene- in analogy to graphene-as free-standing, ...
The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
Enhancing neurite outgrowth from primary neurones and neural stem cells using thermoresponsive hydrogel scaffolds for the repair of spinal cord injury. Journal Articles Refereed ...
Learn more about stem cells by reading Stem Cell-Based Bone Tissue Engineering with a Hydrogel Scaffold Shows Promise for Bone Repair on the Stemodontics® website.
Group led by Dr. Avinash Bajaj from Regional Centre for Biotechnology designed a low molecular weight hydrogel that can maintain sustained and sequential release of combination of drugs and inhibit the tumor progression in murine models. Using the bioconjugation strategies and biocompatible bile acid and peptide scaffolds, Dr. Bajajs group engineered a biocompatible and biodegradable hydrogel. They then entrapped a combination of anti-proliferative (doxorubicin), anti-angiogenic (combretastatin) and anti-inflammatory (dexamethasone) drugs in the hydrogel. Local implantation of the hydrogel reduces the tumor growth kinetics significantly and enhances the median survival. In collaboration with Dr. Ujjaini Dasgupta group at Amity University, Haryana, they have deciphered the in-depth mechanism and found that hydrogel-mediated delivery of combination of drugs alters the sphingolipid metabolism and helps in combating drug resistance.. More details about this research can been read ...
TY - JOUR. T1 - Controlling the Surface Chemistry of a Hydrogel for Spatially Defined Cell Adhesion. AU - Chen, Jeffrey W.. AU - Lim, Kelly. AU - Bandini, Stephen B.. AU - Harris, Greg M.. AU - Spechler, Joshua A.. AU - Arnold, Craig B.. AU - Fardel, Romain. AU - Schwarzbauer, Jean E.. AU - Schwartz, Jeffrey. N1 - Funding Information: The authors thank the New Jersey Commission on Spinal Cord Research (CSCR15IRG002), the National Science Foundation (DMR-1420541), and a New Ideas in the Natural Sciences award from the Princeton Dean for Research for support of this research.. PY - 2019/5/1. Y1 - 2019/5/1. N2 - A two-step synthesis is described for activating the surface of a fully hydrated hydrogel that is of interest as a possible scaffold for neural regeneration devices. The first step exploits the water content of the hydrogel and the hydrophobicity of the reaction solvent to create a thin oxide layer on the hydrogel surface using a common titanium or zirconium alkoxide. This layer serves as a ...
Pages that link to Regulating Volume Transitions of Highly Responsive Hydrogel Scaffolds by Adjusting the Network Properties of Microgel Building Block Colloids ...
TY - JOUR. T1 - Poly-l-Lactic Acid Nanofiber-Polyamidoamine Hydrogel Composites: Preparation, Properties, and Preliminary Evaluation as Scaffolds for Human Pluripotent Stem Cell Culturing. AU - Mauro, Nicolò. AU - Gualandi, Chiara. AU - Visai, Livia. AU - Bloise, Nora. AU - Mauro, Nicolò. AU - Gherardi, Matteo. AU - Laurita, Romolo. AU - Liguori, Anna. AU - Focarete, Maria Letizia. AU - Sampaolesi, Maurilio. AU - Colombo, Vittorio. AU - Ranucci, Elisabetta. AU - Ferruti, Paolo. AU - Manfredi, Amedea. PY - 2016. Y1 - 2016. N2 - Electrospun poly-l-lactic acid (PLLA) nanofiber mats carrying surface amine groups, previously introduced by nitrogen atmospheric pressure nonequilibrium plasma, are embedded into aqueous solutions of oligomeric acrylamide-end capped AGMA1, a biocompatible polyamidoamine with arg-gly-asp (RGD)-reminiscent repeating units. The resultant mixture is finally cured giving PLLA-AGMA1 hydrogel composites that absorb large amounts of water and, in the swollen state, are ...
Corneal endothelial cells (CECs) have limited proliferation ability leading to corneal endothelium (CE) dysfunction and eventually vision loss when cell number decreases below a critical level. Although transplantation is the main treatment method, donor shortage problem is a major bottleneck. The transplantation of in vitro developed endothelial cells with desirable density is a promising idea. Designing cell substrates that mimic the native CE microenvironment is a substantial step to achieve this goal. In the presented study, we prepared polyacrylamide (PA) cell substrates that have a microfabricated topography inspired by the dimensions of CECs. Hydrogel surfaces were prepared via two different designs with small and large patterns. Small patterned hydrogels have physiologically relevant hexagon densities (similar to 2000 hexagons/mm(2)), whereas large patterned hydrogels have sparsely populated hexagons (similar to 400 hexagons/mm(2)). These substrates have similar elastic modulus of native ...
Weve all had booster shots at some point in our lives. You know, you get an immunization injection, then at some point in the future you have to have another round to make sure you have the proper level of immunity.. This can be a major pain (pardon the pun) for many of us. When I received my Hepatitis B vaccine while in dental school, the proper protocol was for a 3 shot series.. Now, in dental school, it was easy. The injections were given by the oral surgery department and I was notified when to return for my next round. However, in the real world this can mean more trips to a doctors office for these follow up visits. This can result in lost work time, taking kids out of school, etc. Not to mention the fact that you actually have to get the injections to ensure immunity. Lots of people either forget or are scared and just dont get them.. Now comes word of a way around these booster injections.. The idea is to place a booster amount in a small pea sized hydrogel capsule that is injected ...
The product is a synthetic hydrogel consisting primarily of water and iodinated cross-linked polyethylene glycol. Injectable through a fine needle, small hydrogel injections are clearly visible in the lung, breast, prostate and other tissues. The hydrogel remains stable and visible in tissue for three months, long enough for radiotherapy, and then is absorbed and cleared from the body, the company said.. ...
Travoprost was encapsulated in various formulations of polylactide microparticles (PM), which were dry blended and suspended in a multi-arm polyethylene glycol (PEG) precursor solution conjugated with fluorescein and injected into small bore tubing prior to cross-linking. The travoprost in the PM/hydrogel matrix was dried in tubing and cut into plugs. Drug release rate from the respective formulations was assessed in PBS at pH 7.4 at 37 C until complete dissolution. The 3-month formulation was evaluated for plug visualization through the tissue in a canine model under illumination with a blue light and yellow filter.. ...
Biomaterial-based regenerative approaches would allow for cost-effective off-the-shelf solution for the treatment of wounds. Hyaluronan (HA)-based hydrogel is one attractive biomaterial candidate because it is involved in natural healing processes, including inflammation, granulation, and reepi-thelialization. Herein, dynamic metal-ligand coordination bonds are used to fabricate moldable supramolecular HA hydrogels with self-healing properties. To achieve reversible crosslinking of HA chains, the biopolymer is modified with pendant bisphosphonate (BP) ligands using carbodiimide coupling and chemoselective click reactions. Hydrogel is formed immediately after simple addition of silver (Ag+) ions to the solution of HA containing BP groups (HA-BP). Compared with previous HA-based wound healing hydrogels, the HA-BP·Ag+ hydrogel is highly suitable for clinical use as it can fill irregularly shaped wound defects without the need for premolding. The HA-BP·Ag+ hydrogel shows antimicrobial ...
China Hot Selling Transparent Debridement Hydrogel, Find details about China Ulcer Wound Dressing, Hydrogel for Burn Wound from Hot Selling Transparent Debridement Hydrogel - Huizhou Foryou Medical Devices Co., Ltd.
ROYSTON, England /ePRNews/ Particle Works - the nano- and microstructured material specialist - has developed a range of alginate and agarose hydrogel beads designed to enable three dimensional cell culture growth. This bead-based…
Objectives: Direct pulp capping is a treatment for preserving the vital pulp. However, a satisfactory material for caries-exposed inflamed pulp in permanent teeth is not currently available. Thus, a biologically-based material that promotes the continued formation of a new dentin-pulp complex is needed. A hydrogel drug delivery vehicle is a promising material, however its cytotoxicity has barely been explored. The aim of this study is to evaluate the cytotoxicity of a hydrogel drug delivery vehicle and its components in a cell culture system in vitro. Methods: The hydrogel solution was prepared by mixing poly(ethylene glycol)maleate-citrate (45% w/v)[PEGMC], acrylic acid (5% w/v)[AA], 2,2-Azobis(2-methylpropionamidine) dihydrochloride photoinitiator (0.1% w/v)[AAPH], and deionized water. Various concentrations of the hydrogel and its components were prepared in the cell culture medium. L929 cells were seeded into 96-well plates at 3x103 cells/well and cultured with each concentration of the ...
The Global Hydrogel market 2017 report is a comprehensive and professional document to deliver the market research data that is relevant for the newly established players in the market. The major leading industry players over the globe are focused in the report with the information including company profiles, specifications and product picture, market share, contact information and sales.. The report has been built by a highly seasoned analyst team and data experts, with containing the graphs besides qualitative analyses and an array of tables. As the report starts with a discussion on the Hydrogel market current state, it goes to the dynamics that affect each segment within it.. The report also avails the detailed theory about the Hydrogel market key segments and growth prospects. The report study presents a competitive landscape for the market that profiles the outstanding market players.. With the help of key inputs from industry experts, the research study of Hydrogel is composed. ...
Taking medication often comes with side effects which range in severity which may even deter people from seeking treatment. Accordingly, there is a need for improved efficiency in drug delivery which can be achieved with the use of a nanoparticle drug delivery system. In order to manufacture drug delivery hydrogel particles at a nanoscale, the behavior of the system must first be understood fundamentally. This study focused on quantifying the amount of a drug, chosen to be DL-propranolol hydrochloride, that diffuses into a poly(n-isopropylacrylamide) (PNIPAm) hydrogel at equilibrium. Three gels were synthesized and soaked in a solution containing DL-propranolol hydrochloride for 14 days, which was found to be the amount of time needed for the drug to reach equilibrium (complete diffusion). After this time period, the gels were then sliced into disks in order for the drug to be extracted. Using UV-visible spectroscopy, the concentration of drug in each disk was analyzed. This data, along with the ...
Ranganath, S.H.,Yang, A.,Chan, Y.Y.,Huang, J.,Krantz, W.B.,Wang, C.-H. (2008). Implantable hydrogel beads entrapping PLGA-paclitaxel microspheres: Exploring the effects of near-zero-order drug release for intracranial chemotherapy. AIChE Annual Meeting, Conference Proceedings : -. [email protected] Repository ...
Due to our aging population, an increase in proximal femur fractures can be expected, which is associated with impaired activities of daily living and a high risk of mortality. These patients are also at a high risk to suffer a secondary osteoporosis-related fracture on the contralateral hip. In this context, growth factors could open the field for regenerative approaches, as it is known that, i.e., the growth factor BMP-7 (bone morphogenetic protein 7) is a potent stimulator of osteogenesis. Local prophylactic augmentation of the proximal femur with a BMP-7 loaded thermoresponsive hydrogel during index surgery of an osteoporotic fracture could be suitable to reduce the risk of further osteoporosis-associated secondary fractures. The present study therefore aims to test the hypothesis if a BMP-7 augmented hydrogel is an applicable carrier for the augmentation of non-fractured proximal femurs. Furthermore, it needs to be shown that the minimally invasive injection of a hydrogel into the mouse femur is
In a new study in pigs, University of California, San Diego bioengineers have shown that a new injectable hydrogel can repair damage from heart attacks,...
TY - JOUR. T1 - Pharmacokinetic and pharmacodynamic evaluation of a novel in situ forming poly(ethylene glycol)-based hydrogel for the controlled delivery of the camptothecins. AU - Lalloo, Anita. AU - Chao, Piyun. AU - Hu, Peidi. AU - Stein, Stanley. AU - Sinko, Patrick J.. PY - 2006/5/30. Y1 - 2006/5/30. N2 - Inadequate drug delivery, due to problems associated with achieving constant therapeutic blood levels, has hampered the use of anticancer agents of the camptothecin (CPT) class. The objective of the current studies was to develop a depot delivery system for the water-soluble analog of CPT, topotecan (TPT). In this study, a 2-phase drug depot consisting of TPT-loaded liposomes entrapped in a poly(ethylene glycol) hydrogel was designed. Physically entrapped unaltered TPT displayed a rapid release rate from the hydrogel. Controlled release was demonstrated in vitro and in vivo from the 2-phase system with constant blood levels being achieved for several days in rats. Cytotoxicity and ...
Luchini A, Longo C, Espina V, Petricoin EF III and Liotta LA, Nanoparticle Technology: Addressing the fundamental roadblocks to protein biomarker discovery, Journal of Materials Chemistry, in press. Longo C, Patanarut A, Bishop B, Zhou W, Ross MM, Espina VE, Pellacani G, Petricoin EF III, Liotta LA, Luchini A, Core-Shell Hydrogel Particles Harvest, Concentrate and Preserve Labile Low Abundance Biomarkers, PLoS ONE, (2009), Volume 4, Issue 3, e4763.. Fredolini C, Meani F, Reeder KA, Rucker S, Patanarut A, Botterell PJ, Bishop B, Longo C, Espina V, Petricoin, EF III, Liotta LA, and Luchini A. Concentration and Preservation of Very Low Abundance Biomarkers in Urine, such as Human Growth Hormone (hGH), by Cibacron Blue F3G-A Loaded Hydrogel Particles Nano Research, (2008) 1: 502 518.. Luchini A, Long DP, Vaisman I, Petricoin EF, Geho D, Liotta LA. Phosphorylation-induced conformational change alters electron transport in peptide molecular junctions, Research Letters Nanotechnology, Volume 2008 ...
VISHWA HYDROGELS PVT LTD - Exporter, Manufacturer & Supplier of Agricultural Hydrogel, Vaaridhar Pusa Hydrogel based in Gurgaon, Haryana, India.
Hydrogel® Mold Compound is an alginate-based white powder that, after mixing with water, cures in 5 minutes to a moist, rubbery material. Use Hydrogel® to make quick, single-use molds, especially when skin contact is required. Hydrogel is ideal when making molds of the face, hands, feet, torso or other external parts of the human body.Hydrogel® can also be used for taxidermy molds and for mold making applications where a delicate or valuable original cannot be molded in polyurethane or silicone liquid rubbers. Plaster, wax, and EasyFlo 60 Liquid Plastic can be cast into Hydrogel molds.Use Hydrogel® Retarder to extend the working time of Hydrogel®.Product FeaturesNon-toxic - safe for exterior body contactEasy to use - Add water, mix and applyGood reproduction of fine detailFast demold timeVariable working time with addition of Retarder HGLow cost View buying information for Hydrogel® Mold Compound here.
Summary of Facts and Submissions. I. The appeal is from the decision of the examining division posted 10 March 2000 refusing the European patent application 97. 919 017.0.. II. The decision was taken on the basis of an amended set of claims. Claim 1 thereof has the following wording (amendments made during the examination appear in bold):. 1. An aqueous composition comprising:. (a) 40-95% by weight of an aqueous solution containing 5-50% surfactant and having a viscosity greater than 300 centipoises and less than 1500 centipoises; and. (b) 5% to 60% by wt. of a hydrogel composition comprising:. (i) 0.1 to 30% by wt. hydrogel composition of at least one polymer soluble in water which polymer is insolubilized when placed in the aqueous solution of item (a);. (ii) 0.2 to 30% by wt. hydrogel composition of a polymer soluble in water, and soluble or dispersible in the aqueous solution of item (a); and. (iii) 1.0 to 60% water insoluble benefit agent entrapped in a network formed by (i) and ...
M89281, Image, IMAGE I MASK hydrating hydrogel sheet mask (retail box of 5), This hydrogel mask delivers instant hydration to skin that is dry, dull or depleted. Cooling and soothing, it refreshes and revives thirsty skin with mineral-rich waters and hyaluronic acid. A blend of amino acids, aloe vera and antioxidant extracts leave skin radiant and glowing. Newly improved hydrogel design offers a better grip and shape to fit every face. The perfect portable addition to every IMAGE Skincare regimen. , HKTVmall The Largest HK Shopping Platform
Glioblastoma (GBM) invasion and migration are key biological behaviors leading to refractoriness to current therapies and infiltration into the non‑tumor brain parenchyma. GBM cell migration is strongly dependent on tumor architecture in vivo, which is absent in traditional two‑dimensional (2D) monolayer culture. The present study applied a three‑dimensional (3D) hydrogel model to rebuild the tumor architecture in vitro. Treatment with NSC23766, a specific inhibitor of Ras‑related C3 botulinum toxin substrate 1 (Rac1), inhibited the mesenchymal invasiveness however triggered the amoeboid motility called mesenchymal‑amoeboid transition (MAT). Notably, NSC23766 stimulated U87 GBM cell migration in the 3D hydrogel. However, this compound inhibited cell motility in 2D monolayer culture without tumor architecture for MAT, suggesting the advantage of 3D hydrogel to investigate tumor cell invasion. Due to the inverse interaction of Rac1 and Ras homolog family member A (RhoA) signaling in the ...
In this paper, inhomogeneous deformation of a temperature-sensitive hydrogel has been studied and analyzed under arbitrary geometric and boundary conditions. We present the governing equations and equilibrium conditions of an isothermal process based on the monophase gel field theory of hydrogel via a variational approach. We have adopted and implemented an explicit form of energy for temperature-sensitive hydrogel in a three-dimensional finite element method (FEM) using a user-supply subroutine in ABAQUS. For verification purpose, a few numerical results obtained by the proposed approach are compared with existing experimental data and analytical solutions. They are all in good agreement. We also provide several examples to show the possible applications of the proposed method to explain various complex phenomena, including the bifurcation, buckling of membrane, buckling of thin film on compliant substrate and the opening and closure of flowers. © 2013 Elsevier Ltd. All rights reserved ...
Free Shipping on most orders over $60. Great Low Price. Vetericyn Plus Antimicrobial HydroGel is a thicker, gel form of the original Vetericyn Wound & Infection Treatment. HydroGel clings to uneven surfaces to stay in place longer before evaporating. Vetericyn Plus Antimicrobial HydroGel cleans, treats and heals wounds and infections without harming healthy tissue and effectively kills antibiotic-resistant strains of bacteria, fungi, viruses and spores. Use Vetericyn Plus Antimicrobial Hydro
Download FINN HydroGel Additive System Specification Sheet on Agriculture XPRT. FINN HydroGel B is a polymer that is able to store water and nutrients up to 500% its own size and weight. Once HydroGel B releases its stored moisture and nutrients to t...
Hydrogel Gel Tahan Lama Untuk Lelaki BAGAIMANA HYDROGEL BOLEH MENJADI BEGITU ..HEBAT? Beginilah caranya bagaimana HYDROGEL bertindak PRESTASI YANG MEMBANGGAK
The Global Hydrogel Market Research Report 2017is a professional and in-depth study on the current state of the Hydrogel industry. In a word, This report studies Hydrogel in Global market, especially in North America, Europe, China, Japan, Southeast Asia and India, focuses on top manufacturers in global market, with capacity, production, price, revenue and market share for each manufacturer. Key companies included in this research are 3M, Conva Tec Inc., Derma Sciences, Smith&Nephew United, Axelgaard, Coloplast, Paul Hartmann, Covidien, NIPRO PATCH, Ashland, ESI BIO, Ambu, KRUUSE, Johnson & Johnson Services Inc., BSN Medical GmbH, Medico Electrodes International Ltd., The Cooper Companies, Inc., H.B. Fuller Company, Altergon Italia Srl, R&D Medical Products Inc., Spes Medica Srl., Katecho Inc., Takiron Co. Ltd., Sekisui Plastics Co. Ltd. and Alliqua Biomedical Inc... Browse complete report @ http://www.reportsweb.com/global-hydrogel-market-research-report-2017. Market Segment by Region, this ...
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Two complementary β-sheet-forming decapeptides have been created that form binary self-repairing hydrogels upon combination of the respective free-flowing peptide solutions at pH 7 and ,0.2 wt %. The component peptides showed little structure separately but formed extended β-sheet fibres upon mixing, which became entangled to produce stiff hydrogels. Microscopy revealed two major structures; thin fibrils with a twisted or helical appearance and with widths comparable to the predicted lengths of the peptides within a β-sheet, and thicker, longer, interwoven fibres that appear to comprise laterally-packed fibrils. A range of gel stiffnesses (G from 0.05 to 100 kPa) could be attained in this system by altering the assembly conditions, stiffnesses that covered the rheological properties desirable for cell culture scaffolds. Doping in a RGD-tagged component peptide at 5 mol % improved 3T3 fibroblast attachment and viability compared to hydrogel fibres without RGD functionalisation ...
As 3D cell-based models continue to grow in popularity it is natural to try and apply existing 2D assays as a way of expanding experimental capabilities, but it is important to remember that large changes in model format can result in new experimental challenges that must first be overcome before useful data can be generated.. A common request that we often get at Visikol is if we can immunolabel microtissues encapsulated or grown in Matrigel; one of the first 3D cell culture options commercially available and a well know protein-based scaffold. Using Matrigel can result in cells expressing exciting biological phenotypes, but it can also introduce some unexpected complications with antibody labels. When immunolabeling tissues and microtissues the challenge is to get even labeling from the primary antibody. When you encapsulate tissues inside a hydrogel you have introduced an additional physical obstacle that the antibodies must first move through before they can begin to diffuse into the tissue. ...
Focal presented rat data indicating that its hydrogel can reduce internal scarring and inflammation following laminectomy, Read the full 162 word article
EN] Plasma-liquid electrochemistry was successfully used to synthesize gold nanoparticles in a watery background (AuNPs) and also embedded within a hydrogel network (PVA-AuNPs) without using any capping or reducing agents. Nanoparticles of different sizes and morphologies were obtained and the effect of the precursor concentration on the NPs size was examined. The effect of the hydrogel was also studied and it is though that it is responsible of stabilizing and avoiding the agglomeration of the NPs. This atmospheric-microplasma set-up was then used to create gold and silver mixed nanoparticles (Au-AgNPs) and PVA capped with these bimetallic nanoparticles (PVA-AuAgNPs). Their absorption properties were analysed using ultraviolet-visible (UV-Vis) spectroscopy and their size and shape using transmission electron microscopy (TEM). Antibacterial characteristics of the NPs embedded within the PVA matrix were also tested against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) showing a ...
Just stumbled upon this. Plants are grown on a thin film of hydrogel commonly used in diapers. Anyone tried that with CPs? I can see pings growing on
TY - JOUR. T1 - An injectable platelet lysate-hyaluronic acid hydrogel supports cellular activities and induces chondrogenesis of encapsulated mesenchymal stem cells. AU - Jooybar, Elaheh AU - Abdekhodaie, M.J.. AU - Alvi, Mansour. AU - Karperien, Marcel. AU - Dijkstra, Pieter Jelle. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Developing scaffolds that can provide cells and biological cues simultaneously in the defect site is of interest in tissue engineering field. In this study, platelet lysate (PL) as an autologous and inexpensive source of growth factors was incorporated into a cell-laden injectable hyaluronic acid-tyramine (HA-TA) hydrogel. Subsequently, the effect of platelet lysate on cell attachment, viability and differentiation of human mesenchymal stem cell (hMSCs) toward chondrocytes was investigated. HA-TA conjugates having a degree of substitution of 20 TA moieties per 100 disaccharide units were prepared and crosslinked in the presence of horseradish peroxidase and low concentrations of ...
These are pictures showing the changing shape of the hydrogel as it walks in a water environment in responses to changes of temperature. (Credit: Kim et al. Nature Materials). In research published in Nature Materials, a team led by scientists from the RIKEN Center for Emergent Matter Science in Japan has developed a new hydrogel that works like an artificial muscle-quickly stretching and contracting in response to changing temperature. They have also managed to use the polymer to build an L-shaped object that slowly walks forward as the temperature is repeatedly raised and lowered. Hydrogels are polymers that can maintain large quantities of water within their networks. Because of this, they can swell and shrink in response to changes in the environment such as voltage, heat, and acidity. In this sense they are actually similar to the plant cells, which are able to change shape as the amount of water within them changes in response to environmental conditions.. However, most hydrogels do this ...
Hydrogels generated in this manner are sometimes called 'permanent' hydrogels. Hydrogels are prepared using a variety of ... Chemical hydrogels have covalent cross-linking bonds, whereas physical hydrogels have non-covalent bonds. Chemical hydrogels ... The term 'hydrogel' was coined in 1894. The crosslinks which bond the polymers of a hydrogel fall under two general categories ... Culturing cells: Hydrogel-coated wells have been used for cell culture. Biosensors: Hydrogels that are responsive to specific ...
Impregnated hydrogel dressings are dry dressings (e.g. gauzes) saturated with an amorphous hydrogel. Sprayable hydrogel ... Self-assembling designer peptide hydrogels are another type of synthetic hydrogel in development. Natural hydrogel dressings ... The efficacy of hydrogel dressings has been assessed on various wound types. There is some evidence to suggest that hydrogels ... Hydrogel dressings can also be designed to respond to changes in the microenvironment at the wound bed. Hydrogel dressings ...
For example, a hydrogel based on gum tragacanth increases the water content of clay soil by up to 5.35% and of sandy loam by up ... these may be mitigated with hydrogels. Hydrogels are hydrophilic crosslinked polymers that form three-dimensional molecular ... Hydrogels of different kinds could be useful in agriculture, reducing drought stress in plants, making better use of irrigation ... Hydrogels developed for this purpose include polymers of oligooxyethylene methacrylate, linked by ionic and covalent bonds to a ...
Although only being able to produce short hydrogel fibers, production of hydrogel fiber by polymerizing the hydrogel network ... Hydrogel fiber is a hydrogel made into a fibrous state, where its width is significantly smaller than its length. The ... Hydrogel fiber can be used to fabricate scaffolds for cell growth and drug release. Stimuli-responsive hydrogel fibers can be ... But the production of hydrogel fiber can be challenging as the hydrogel is crosslinked and can not be shaped into a fibrous ...
... is the hydrogel viscosity Typical Rf-PEG hydrogel diffusivities for 2 nm quantum dots are on the order of 10−16 m2/s, so ... Hydrogel encapsulation of the QDs opens up a new range of applications, such as: Biosensors Enzymes and other bio-active ... The formation of hydrogels is a phenomenon observed in superabsorbent polymers, or "slush powders," in which the polymer, often ... It has been observed that a stable hydrogel can only be formed with PEG backbones weighing between six and ten thousand Daltons ...
... are not to be confused with nanogel, a nanoparticle composed of a hydrogel. The synthesis of ... The responsiveness of hydrogels is a result of their molecular structure and polymer networks. Hydrogel nanoparticles have a ... Hydrogels are controlled drug delivery agents that can be engineered to have desired properties. Specifically, hydrogels can be ... The stimulus-sensitivity of hydrogels allow for a responsive release system where the hydrogels can be designed to deliver the ...
... are a specialized type of polymer hydrogel. A hydrogel is a macromolecular polymer gel constructed of a ... hydrogels Polyethylene glycol(PEG) polymers are synthetic materials that can be crosslinked to form hydrogels. PEG hydrogels ... Self-healing hydrogels encompass a wide range of applications. With a high biocompatibility, hydrogels are useful for a number ... A hybrid of these two polymer types allows for the creation of hydrogels with novel properties. An example of a hybrid hydrogel ...
Hydrogel from wood-based nanofibrillated cellulose (NFC) is used as a matrix for 3D cell culture. As plant based material, it ... NFC hydrogel in 3D cell culture offers a platform for various biomedical applications. Different cell lines and cell types have ... GrowDex is NFC hydrogel for 3D cell culture commercialized by UPM, Finland. NFC fiber network structure and dimensions in ... The nanocellulose hydrogel can be completely degraded by cellulase enzyme treatment while retaining the 3D cell structures. ...
2015). Photonic hydrogel sensors. Biotechnology advances. 34. 10.1016/j.biotechadv.2015.10.005. Ranft, Annekathrin & ... "Download citation of Photonic hydrogel sensors". ResearchGate. Retrieved 2020-05-25. "Download citation of 1D photonic defect ... "Photonic hydrogel sensors". Biotechnology Advances. Trends in In Vitro Diagnostics and Mobile Healthcare. 34 (3): 250-271. doi: ...
Chatterji, Prabha R. (5 August 1990). "Interpenetrating hydrogel networks. I. The gelatin-polyacrylamide system". Journal of ...
Van Vliet, Krystyn J. (2006). "3.032 Mechanical Behavior of Materials" Cacopardo, Ludovica (Jan 2019). "Engineering hydrogel ...
Abad, "PVP-Carrageenan Hydrogel Dressing." 2008. De Guzman, "Radiation-Sterilized Honey Alginate Wound Dressing for Exudating ... Between 2001 and 2005, a polyvinylpyrrolidone carrageenan hydrogel dressing for burns and wounds was developed by the PNRI as ... Abad, Lucille V. "PVP-Carrageenan Hydrogel Dressing." PNRI, July 2008. Retrieved July 10, 2017. Abad, Lucille V. "Radiation ...
erratum) M. L. Oyen (5 December 2013). "Mechanical characterisation of hydrogel materials". International Materials Reviews. 59 ...
She created polymer hydrogel beads that are responsive to enzymes. She is working with the Medical Research Scotland to create ... Ulijn, Rein V.; McConnell, Gail; Thornton, Paul D. (2005). "Enzyme responsive polymer hydrogel beads". Chemical Communications ...
"Editorial - Should Silicone Hydrogels be Placed in a Separate FDA Soft Contact Lens Category?". www.siliconehydrogels.org. ... Newer soft lens materials include silicone-hydrogels to provide more oxygen to your eye while you wear your lenses. The first ... "The FDA has created the 4 Lens groups of hydrogels Materials to clarify categories of similar polymers for investigating ... "Looking at Silicone Hydrogels Across Generations". www.optometricmanagement.com. Optometric Management. Retrieved 18 June 2016 ...
Jung S, Kim BK, Lee S, Yoon S, Im H, Kim SK (2018). "Multiplexed on-chip real-time PCR using hydrogel spot array for microRNA ... Hydrogel fibers provide an intriguing option for biocompatible material for drug delivery and bioprinting of materials that can ... Sun, F.; Zhang, W.-B.; Mahdavi, A.; Arnold, F. H.; Tirrell, D. A. (2014-07-21). "Synthesis of bioactive protein hydrogels by ... The synthesis of gel particles also known as hydrogels, microgels, and nanogels, has been an area of interest for researchers ...
... also aids synthesis of nanocomposite hydrogels. These gels are made of water-swellable nano-scale clay ( ... Haraguchi, K. (2008). "Nanocomposite hydrogels". Current Opinion in Solid State and Materials Science. 11 (3-4): 47-54. Bibcode ... Haraguchi, K.; Takehisa T. (2002). "Nanocomposite hydrogels: a unique organic-inorganic network structure with extraordinary ...
... continuing to offer peptide-based hydrogels amongst other biomaterials. The hydrogels can be used to improve the quality of ... The synthetic peptide hydrogels were so successful that she set up the spin-out company PeptiGelDesign, a group which worked to ... Miller was awarded a small grant from the University of Manchester to develop the synthesis of peptide-based hydrogels. ... Yan, Hui; Saiani, Alberto; Gough, Julie E.; Miller, Aline F. (1 October 2006). "Thermoreversible Protein Hydrogel as Cell ...
Stimuli-responsive gels (hydrogels, when the swelling agent is an aqueous solution) are a special kind of swellable polymer ... Richter, A.; Paschew, G.; Klatt, S.; Lienig, J.; Arndt, K.-F.; Adler, H.-J. (2008). "Review on Hydrogel-based pH Sensors and ... To avoid the electrolysis of water hydrogel-based microfluidic devices are mainly based on temperature-responsive polymers with ... Microvalves based on stimuli-responsive hydrogels show some advantageous properties such as particle tolerance, no leakage and ...
... is classified as a hydrogel. Gelatin is nearly tasteless and odorless with a colorless or slightly yellow appearance. ... Biotechnology: Gelatin is also used in synthesizing hydrogels for tissue engineering applications. Gelatin is also used as a ... "Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for ...
Dumville JC, Stubbs N, Keogh SJ, Walker RM, Liu Z (February 2015). Dumville JC (ed.). "Hydrogel dressings for treating pressure ... Cochrane reviews summarise evidence on alginate dressings, foam dressings, and hydrogel dressings. Due to a lack of robust ...
The first step in this direction was hydrogel-tissue chemistry (HTC), in which "specific classes of native biomolecules in ... He is known for creating and developing the technologies of hydrogel-tissue chemistry (e.g., CLARITY, STARmap) and optogenetics ... Viviana Gradinaru; Jennifer Treweek; Kristin Overton; Karl Deisseroth (2018). "Hydrogel-tissue chemistry: principles and ... A key feature of HTC is that the hydrogel-tissue hybrid "becomes the substrate for future chemical and optical interrogation ...
At its simplest, a bioreactor space will be created between tissue layers through the use of hydrogel injections to create a ... Zhu, Junmin (June 2010). "Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering". Biomaterials. 31 ( ... "Cell-Type Specific Four-Component Hydrogel". PLOS ONE. 9 (1): e86740. Bibcode:2014PLoSO...986740A. doi:10.1371/journal.pone. ... Tuning the Mechanical Properties of Chondroitin Sulfate Hydrogels by Copolymerization with Oligo (ethylene glycol) Diacrylates ...
Cochrane Wounds Group) (August 2022). "Hydrogel dressings for venous leg ulcers". The Cochrane Database of Systematic Reviews. ...
"Modular Integration of Hydrogel Neural Interfaces". ACS Central Science. 7 (9): 1516-1523. doi:10.26434/chemrxiv.14541432. PMC ... even more advanced neural interfaces that can be highly customized and include materials such as photoresists and hydrogels. ...
Due to this it is used widely in wound care products, including glycerin based hydrogel sheets for burns and other wound care. ... Stout, Edward I.; McKessor, Angie (February 2012). "Glycerin-Based Hydrogel for Infection Control". Advances in Wound Care. 1 ( ...
Li J, Li X, Ni X, Wang X, Li H, Leong KW (August 2006). "Self-assembled supramolecular hydrogels formed by biodegradable PEO- ... Lu HD, Charati MB, Kim IL, Burdick JA (March 2012). "Injectable shear-thinning hydrogels engineered with a self-assembling Dock ... Deng W, Yamaguchi H, Takashima Y, Harada A (2007-07-02). "A chemical-responsive supramolecular hydrogel from modified ... Appel EA, del Barrio J, Loh XJ, Scherman OA (September 2012). "Supramolecular polymeric hydrogels". Chemical Society Reviews. ...
Kwok A. Y., Qiao G. G., Solomon D. H. (2004). "Synthetic hydrogels 3. Solvent effects on poly(2-hydroxyethyl methacrylate) ...
Hydrogels are beneficial because they have a high water content, which allows the ease of nutrients and small materials to pass ... Hydrogel scaffolds are created by cross-linking hydrophilic polymers through various reaction such as free radical ... Zhu J, Marchant RE (September 2011). "Design properties of hydrogel tissue-engineering scaffolds". Expert Review of Medical ...
Early 2020s Hydrogels are used to develop system that capture moisture (e.g. at night in a desert) to cool solar panels or to ... "Hydrogel helps make self-cooling solar panels". Physics World. 12 June 2020. Retrieved 28 April 2022. Shi, Ye; Ilic, Ognjen; ... Atwater, Harry A.; Greer, Julia R. (14 May 2021). "All-day fresh water harvesting by microstructured hydrogel membranes". ...
Lysine-based dendritic hydrogel (PEG-LysNH2). Not available. Sealant. The cross-linked hydrogel forms an adhesive physical ... The Efficacy of a Lysine-Based Dendritic Hydrogel Does Not Differ From Those of Commercially Available Tissue Sealants and ...
Agarose hydrogel composite supports microgreen cultivation under terrestrial and microgravitational conditions. ... However, pristine hydrogels contain mostly ultra-micro pores and lack air-filled porosity for root zone aeration. Herein we ... An Agarose Hydrogel Composite Has Possible Applications For Space Farming. By Keith Cowing ... Abstract: Agarose hydrogel composite supports microgreen cultivation with enhanced porosity and continuous water supply under ...
title = {Biomimetic Hydrogel Materials},. author = {Bertozzi, Carolyn},. abstractNote = {Novel biomimetic hydrogel materials ... Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized ... Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized ... Flexible hydrogel-based functional composite materials Patent Song, Jie; Saiz, Eduardo; Bertozzi, Carolyn R; ... ...
... , Acryderm, Aquaflo, Aquagauze, Carradres, Carraguaze, Carrasyn, Dermagauze, Felxigel, SAF-Gel, Solosite, ... Hydrogel Dressing. Hydrogel Dressing Aka: Hydrogel Dressing, Acryderm, Aquaflo, Aquagauze, Carradres, Carraguaze, Carrasyn, ... These images are a random sampling from a Bing search on the term "Hydrogel Dressing." Click on the image (or right click) to ... Infected wound (amorphous hydrogels such as Intrasite). *Monitor wound daily if infected ...
Researchers have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a ... Hydrogel could repair heart attack damage Posted by Future Timeline in categories: biotech/medical, materials. ... Researchers have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a ...
Stanford researchers are working on a hydrogel that may help mend damaged cartilage. ... Stanford: Research on Cartilage-Healing Hydrogel It has the texture of Jell-O and it shows promise in being used in a simple ... Stanford researchers are working on a hydrogel that may help mend damaged cartilage.. It has the texture of Jell-O and it shows ... After six months, Golds research found patients treated with hydrogel had less pain and more healthy cartilage filled the hole ...
Concurrent reaction and diffusion in photo-responsive hydrogels. Wed, 2019-01-09 00:24 - Lihua Jin hydrogel ... The technique is applied to PNIPAm hydrogels with. low cross-link densities. The maximum force generated by the hydrogel. ... Axisymmetric periodic cone cracks in Hydrogel. Mon, 2022-01-10 06:12 - Muthukumar M hydrogel ... Here is our recent paper "Fatigue Fracture of Self-Recovery Hydrogels". To the hydrogel community, this paper distinguishes the ...
Perk up tired eyes with a surge of moisture from Mary Kay Hydrogel Eye Patches.. ... Mary Kay® Hydrogel Eye Patches use the fun delivery system of hydrogel - water suspended in a gel matrix - to flood the eye ...
Visit the CooperVision blog page to find out about silicone hydrogel contact lenses and eye care at coopervision.com ... Silicone hydrogel lenses offer a higher rate of oxygen transmission (theres our "Dk/t" number) than standard hydrogels ... Looking for extended-wear comfort? Ask about silicone hydrogel. Now you know more about silicone hydrogel contact lenses. So if ... Silicone hydrogel: Its a term you may have heard used before with contacts, but not fully understood. Dont worry, youre not ...
Grad student Tiffany Suekama traveled to Japan to work with a researcher known for pioneering work on double-network hydrogels ... Have you eaten a piece of Jell-O lately? It is a hydrogel. Have you ever worn a contact lens? Hydrogel. Changed a baby diaper ... Professor Jian Ping Gong is known for her work on double-network hydrogels. These DN hydrogels were the first to be identified ... Hydrogels are three-dimensional materials that are hydrophilic, or water loving. Fully swollen hydrogels typically contain more ...
We have developed a tool box of hydrogel nanoparticles (NPs) with the biodistribution and tissue tropism characteristics for ...
... because of Burkholderia cepecia contamination. ... Regenecare HA Hydrogel is a topical product is used for temporary relief of pain and itching associated with minor burns, ... 2, 2020 that it is voluntarily recalling one lot of Regenecare HA Hydrogel because of two customer complaints of visible ...
Promising hydrogels are hyaluronic acid, alginate or agarose as well as synthetic hydrogels based on Polyethylene glycol, ... Hydrogels are considered as potential candidates for cartilage replacement because they are biocompatible and have mechanical ... The frictional properties of soft hydrogels in combination with the lubrication fluid can be measured using a rheometer with a ... The search for high quality implants initiated the research on cartilage replacement by hydrogels, which should assume the role ...
Buy Erno Laszlo Detoxifying Hydrogel Mask (Single) online at SkinStore with free shipping! We have a great range of Erno Laszlo ... Rejuvenate dull complexions with the Erno Laszlo Detoxifying Hydrogel Mask. The innovative gel-like mask moulds to your facial ... Rejuvenate dull complexions with the Erno Laszlo Detoxifying Hydrogel Mask. The innovative gel-like mask moulds to your facial ...
First patient in Canada has been treated with SpaceOAR hydrogel at the Princess Margaret Cancer Centre, University Health ... SpaceOAR hydrogel is initially implanted as a liquid that solidifies into a soft hydrogel that pushes the prostate and rectum ... Augmenix Announces First Prostate Cancer Patient Treated with SpaceOAR® Hydrogel in Canada Princess Margaret Cancer Centre to ... With SpaceOAR hydrogel, physicians can help reduce this risk by placing a hydrogel barrier to separate the prostate from ...
RED GINSENG VITALIZING HYDROG EL MASK- niacinamide, adenosine patch. Out of scope - Out of scope for RxNorm and will not ... RED GINSENG VITALIZING HYDROG EL MASK- niacinamide, adenosine patch. To receive this label RSS feed. Copy the URL below and ... RED GINSENG VITALIZING HYDROG EL MASK- niacinamide, adenosine patch. If this SPL contains inactivated NDCs listed by the FDA ... RED GINSENG VITALIZING HYDROG EL MASK- niacinamide, adenosine patch. Number of versions: 1. ...
Home » Augmenix wins Japanese reimbursement for SpaceOar hydrogel. Augmenix wins Japanese reimbursement for SpaceOar hydrogel. ... "SpaceOar hydrogel is a proven solution that can make a life-changing difference to men receiving prostate cancer radiotherapy. ... It is our goal to be able to provide global access to SpaceOar hydrogel, a minimally invasive intervention, that significantly ... Augmenix said yesterday that its SpaceOar hydrogel won national reimbursement in Japan from the Ministry of Health, Labour & ...
... hydrogel lip patch will help smooth, revitalize, and plump up your lips! Collagen and 24k gold keep your lips hydrated while ... This strawberry flavored, hydrogel lip patch will help smooth, revitalize, and plump up your lips! Collagen and 24k gold keep ...
SpaceOAR Hydrogel is clinically shown to minimise urinary, sexual and bowel side effects, and protect quality of life for ... Without SpaceOAR Hydrogel. Without the presence of SpaceOAR Hydrogel, high dose radiation is more likely to reach the rectum.1, ... Without SpaceOAR Hydrogel. Without the presence of SpaceOAR Hydrogel, high dose radiation is more likely to reach the rectum.1, ... What is SpaceOAR Hydrogel? SpaceOAR Hydrogel is clinically shown to minimise urinary, sexual and bowel side effects, and ...
Pasientsikkerhetskampanjen skal bedre din sikkerhet og sørge for at dine rettigheter hele tiden står i fokus når du er på sykehus
... imprinted hydrogel layer sensor chips showed larger SPR signal change in response to a target lectin than nonimprinted hydrogel ... On the other hand, the SPR signal change of the lectin-imprinted hydrogel layer chip in the presence of other lectin was very ... Molecularly imprinted hydrogel layer SPR sensor chips with lectin-recognition sites, which were prepared via surface-initiated ... The larger SPR signal change was attributed to the strong affinity constant of the lectin-imprinted hydrogel layer for the ...
US-2014105960-A1 chemical patent summary.
Injectable Chitosan-Based Thermosensitive Hydrogel/Nanoparticle-Loaded System for Local Delivery of Vancomycin in the Treatment ... where Wd is the weight of the dry hydrogel at t=0, We is the weight of the swollen hydrogel at time t, and Wo is the weight of ... The results for hydrogel swelling are shown in Figure 3H, indicating the hydrogels with and without NPs displayed high water ... The hydrogels were prepared using the above method and then the hydrogel samples were frozen in liquid nitrogen, and then ...
... transurethral injection with polyacrylamide hydrogel may alleviate urinary incontinence symptoms. Repeat injections did not ... Transurethral Polyacrylamide Hydrogel Injection Therapy in Women Not Eligible for Midurethral Sling Surgery Female Pelvic Med ... Objectives: This study aims to determine the effects of transurethral polyacrylamide hydrogel injection in patients considered ... Methods: In this prospective observational study, 81 patients received treatment with transurethral polyacrylamide hydrogel ...
CNP Hydro Gel review. Developed alongside Team Sky, the CNP Hydro Gel aims to deliver both a sustained energy boost and to aid ... The CNP Hydro Gel is available in two flavours: pineapple, and passion fruit, which we tested (CNP also produce a Hydro Gel Max ... The CNP Hydro Gel is a pleasant gel that has a nice taste, is easy on the stomach, and delivers a more sustained energy boost ... A natural energy gel (although not organic), as gels go the CNP Hydro gel is fairly liquidy. The reason for this is that the ...
157h) Engineering Nanoscale Hydrogel Particles Entrapping Bovine Hemoglobin as Temperature and pH Sensitive Oxygen Carriers. * ... In this work, temperature and pH sensitive nanoscale hydrogel particles were engineered to respond to physiological conditions ... Temperature sensitive pNIPA nanoscale hydrogel particles exposed to a reduction in temperature from 40oC to 29oC exhibited ... The following physical properties of the hemoglobin entrapped hydrogel particles were characterized: oxygen affinity, ...
Sprayable hydrogel to keep internal organs scar-free after surgery. TYBR is developing a hydrogel spray to prevent internal ...
Cellulose Hydrogel Sheet Mask. It contains a rich blend of silk peptides, hyaluronic acid, arbutin, and NAG (n-acetyl ... Replenish and brighten dry, aging skin with the Prosana® Cellulose Hydrogel Sheet Mask. It contains a rich blend of silk ... Replenish and brighten dry, aging skin with the Prosana® Cellulose Hydrogel Sheet Mask. It contains a rich blend of silk ... Replenish and brighten dry, aging skin with the Prosana® Cellulose Hydrogel Sheet Mask. It contains a rich blend of silk ...
... is a glycerine-based hydrogel, specifically formulated to provide a moist wound healing ...
... based hydrogel and kept intact in the hydrogel. Fast electron transfer mediated by Prussian blue (PB, hexacyanoferrate) ... Hydrogel-based electrochemical sensor for non-invasive and continuous glucose monitoring Author(s): Habeen Park; Ji-Young Lee; ... We hereby present a hydrogel-based electrochemical (H-EC) sensor to monitor the glucose level, non-invasively. Glucose oxidase ... as well as the validation of the hydrogel-based electrochemical (H-EC) device, were applied to the on-body glucose monitoring. ...
  • Researchers have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a heart attack event. (lifeboat.com)
  • Last November, Augmenix said that the American Medical Association established a Current Procedural Terminology code for its SpaceOar hydrogel and similar devices, with the Centers for Medicare and Medicaid Services setting a payment rate for procedures with the injectable. (massdevice.com)
  • They developed an injectable hydrogel that ensures optimal cartilage repair combating painful joints. (liof.nl)
  • Our injectable hydrogel has been developed for repair of cartilage defects in joints. (liof.nl)
  • The injectable gel-like material, which is called a hydrogel, that the UCLA researchers developed helps this repair process by forming a scaffold inside the wound that acts as like an artificial extracellular matrix, and the new tissue grows around that. (scitechdaily.com)
  • Furthermore, surging technological developments in wound closure methods, like injectable stimuli-responsive amorphous hydrogels for trauma patients and military workers to stop bleeding are some factors that are impelling the industry growth. (ibmag.com)
  • A recent study described a novel injectable hydrogel containing anti-cancer agents, which potentially may improve drug efficacy and reduce systemic toxicity by allowing clinicians to control the timing and location of drug delivery non-invasively. (bruker.com)
  • This allows the hydrogel to be used in an injectable formulation while avoiding systemic distribution. (bruker.com)
  • The injectable and photoresponsive collagen/γ-PGA hydrogels developed in this study may be useful for drug delivery, tissue engineering, and cell-based cancer therapy," the authors conclude. (bruker.com)
  • We engineered an injectable nanofiber-hydrogel composite (NHC) with interfacial bonding to provide mechanical strength and porosity and examined its effect on repair and neural tissue regeneration in an adult rat model of spinal cord contusion. (nin.nl)
  • Silicone hydrogel: It's a term you may have heard used before with contacts, but not fully understood. (coopervision.com)
  • Part of this advancement is due to the use of silicone hydrogel. (coopervision.com)
  • Silicone hydrogel lenses are all about bringing the oxygen permeability (the ability to allow oxygen to pass through) of silicone with the comfort of hydrogel (composed mostly of water) into contact lenses that can be safely and comfortably worn for a prescribed extended period. (coopervision.com)
  • Silicone hydrogel lenses offer a higher rate of oxygen transmission (there's our "Dk/t" number) than standard hydrogels contacts and certainly far beyond the hard glass eye contacts of the past. (coopervision.com)
  • Now you know more about silicone hydrogel contact lenses. (coopervision.com)
  • And speaking of visiting your eye doctor, CooperVision Biofinity lenses are silicone hydrogel. (coopervision.com)
  • This PhD project investigated the ramifications of air-cured and nitrogen-cured manufacturing processes during silicone hydrogel contact lens manufacture in terms of lens surface characterisation and clinical performance. (bl.uk)
  • Mimicking these tissues with synthetic hydrogels would advance tissue engineering for repair of damaged or diseased tissues. (livescience.com)
  • Promising hydrogels are hyaluronic acid, alginate or agarose as well as synthetic hydrogels based on Polyethylene glycol, Polyvinyl alcohol (PVA) or Polyacrylate. (anton-paar.com)
  • However, toxicity issues are the cause of significant difficulty in utilizing synthetic hydrogels, and similar efficacy is often difficult to achieve with natural compounds. (bruker.com)
  • Compared with natural hydrogels, synthetic hydrogels have better mechanical strength and stability and wider adjustable range of structure and performance, which make them play an important role in biomedical, biosensing, and tissue engineering fields. (penelopethemovie.com)
  • 67 This is why many of these stimuli-responsive smart hydrogels have been used for various applications, including controlled drug release systems, sensors, cell culture substances, and flow control. (criterionessays.com)
  • In the past 15 years, a number of DNA-functionalized hydrogels have been used in making biosensors, 54 , 57 , 66 , 75 , 76 controlled release systems, 55 , 77-79 biocompatible matrix, 80 and stimuli responsive materials. (criterionessays.com)
  • Most of the research has been done on hydrogel-based sensors, focusing on the gel's physical properties such as swelling or phase transition through making stimuli-responsive smart gels, 84-86 and few colorimetric sensors have been demonstrated. (criterionessays.com)
  • Figure (10): Three stimuli responsive gel-to-sol transition in DNA-functionalized hydrogels. (criterionessays.com)
  • Figure (10) shows that three stimuli responsive gel-to-sol transition in DNA-functionalized hydrogels are formed from a solution, and can be made into various shapes and sizes. (criterionessays.com)
  • These findings provide new insights for designing controlled drug release from stimuli-responsive hydrogels, including autonomously switch on/off drug release in response to physical and chemical stimuli. (rsc.org)
  • This book reviews recent advances and developments of various classes of stimuli responsive polymer materials, different type of hydrogels for biomedical and pharmaceutical devices, scaffolds for tissue regeneration, and stimuli-responsive sensors or separation processes. (novapublishers.com)
  • Se realizó una búsqueda bibliográfica en las bases de datos directas de PubMed, Google Scholar, Web of Science y Science hasta el 2021. (bvsalud.org)
  • TORONTO--( BUSINESS WIRE )--Augmenix, Inc., a medical technology company that develops, manufactures, and sells proprietary absorbable hydrogels that separate and protect organs at risk during radiotherapy, today announced that the first patient in Canada has been treated with SpaceOAR hydrogel at the Princess Margaret Cancer Centre, University Health Network, Toronto. (businesswire.com)
  • SpaceOAR hydrogel is the first absorbable spacer designed to separate the rectum and prostate to reduce the risk of rectal toxicity during radiotherapy. (businesswire.com)
  • Princess Margaret will also initiate a 20-patient pilot study to assess the use of SpaceOAR hydrogel in the treatment of prostate cancer. (businesswire.com)
  • Recent clinical data show that SpaceOAR hydrogel helps to significantly reduce the risk of rectal and urinary toxicities and loss of sexual function associated with radiation therapy in the treatment of prostate cancer," said John Pedersen, CEO of Augmenix. (businesswire.com)
  • We are pleased that the first patient to be treated with SpaceOAR hydrogel in Canada took place at the Princess Margaret Cancer Centre, which is globally recognized for innovation and excellence in cancer care. (businesswire.com)
  • With SpaceOAR hydrogel, physicians can help reduce this risk by placing a hydrogel barrier to separate the prostate from adjacent healthy tissue. (businesswire.com)
  • SpaceOAR hydrogel is initially implanted as a liquid that solidifies into a soft hydrogel that pushes the prostate and rectum apart. (businesswire.com)
  • In January 2017, Augmenix announced three-year post-treatment data from a prospective, randomized, multi-center, patient-blinded clinical trial showing that patients treated with SpaceOAR hydrogel prior to prostate cancer radiotherapy demonstrated significant rectal (bowel), urinary, and sexual benefit through three years of follow up 1 . (businesswire.com)
  • During radiotherapy the spacer resulted in a 73.5% reduction in rectal V70 radiation dose and a 49% reduction in median penile bulb radiation dose in patients treated with SpaceOAR hydrogel compared to men who did not receive SpaceOAR hydrogel (Control). (businesswire.com)
  • Among men who were sexually potent at baseline, the analysis showed that men in the SpaceOAR hydrogel arm were better able to maintain erections sufficient for intercourse through 3 years of follow-up (p=0.03). (businesswire.com)
  • Our team at Princess Margaret looks forward to using SpaceOAR hydrogel as indicated as part of our ongoing efforts to bring patients the most effective treatment options while reducing the side effects of radiation therapy. (businesswire.com)
  • SpaceOAR hydrogel is intended to temporarily position the anterior rectal wall away from the prostate during radiotherapy for prostate cancer and in creating this space, SpaceOAR hydrogel reduces the radiation dose delivered to the anterior rectum. (businesswire.com)
  • SpaceOAR hydrogel is licensed in Canada, cleared by the U.S. Food and Drug Administration and is currently being used in the majority of leading cancer centers in the United States. (businesswire.com)
  • Augmenix said yesterday that its SpaceOar hydrogel won national reimbursement in Japan from the Ministry of Health, Labour & Welfare. (massdevice.com)
  • The Belford, Mass.-based company's SpaceOar hydrogel is designed to separate the prostate from the rectal wall during radiation treatment for prostate cancer. (massdevice.com)
  • We are delighted that SpaceOar hydrogel is now available through the MHLW national reimbursement programme for all men undergoing prostate cancer radiotherapy treatment throughout Japan. (massdevice.com)
  • It is our goal to be able to provide global access to SpaceOar hydrogel, a minimally invasive intervention, that significantly benefits patients by reducing the side effects of radiation exposure. (massdevice.com)
  • SpaceOar hydrogel is a proven solution that can make a life-changing difference to men receiving prostate cancer radiotherapy. (massdevice.com)
  • What is SpaceOAR Hydrogel? (bostonscientific.com)
  • SpaceOAR Hydrogel is clinically shown to minimise urinary, sexual and bowel side effects, and protect quality of life for prostate cancer patients undergoing radiation therapy. (bostonscientific.com)
  • Without the presence of SpaceOAR Hydrogel, high dose radiation is more likely to reach the rectum. (bostonscientific.com)
  • Why SpaceOAR Hydrogel? (bostonscientific.com)
  • Hear from prostate cancer survivors who have benefited from SpaceOAR Hydrogel as well as from the physicians who provide it to their patients. (bostonscientific.com)
  • Sign up to receive more information about SpaceOAR Hydrogel. (bostonscientific.com)
  • Our patient education team can provide you with details about how SpaceOAR Hydrogel works, what to ask your doctor and how to find a doctor in your area. (bostonscientific.com)
  • As with any medical treatment, there are some risks involved with the use of SpaceOAR Hydrogel. (bostonscientific.com)
  • Upon discovering he had prostate cancer, Dr. Gray chose proton beam radiation therapy and insisted that SpaceOAR Hydrogel be part of his treatment plan. (spaceoar.com)
  • SpaceOAR Hydrogel is intended to temporarily position the anterior rectal wall away from the prostate during radiotherapy for prostate cancer and in creating this space it is the intent of SpaceOAR Hydrogel to reduce the radiation dose delivered to the anterior rectum. (spaceoar.com)
  • The SpaceOAR Hydrogel is composed of biodegradable material and maintains space for the entire course of prostate cancer radiotherapy treatment. (spaceoar.com)
  • Implantation of hyaluronic acid hydrogel prevents the pain phenotype in a rat model of intervertebral disc injury. (channel969.com)
  • Bone regeneration using hyaluronic acid-based hydrogel with bone morphogenic protein-2 and human mesenchymal stem cells. (bvsalud.org)
  • Fully swollen hydrogels typically contain more than 90 percent water. (livescience.com)
  • the hydrophilicity of the chains means that when immersed in waters hydrogels can absorb big quantities of water (a hydrogel can contain more than 90% water), which causes the gel to swell, maintaining its 3D structure. (penelopethemovie.com)
  • We engineered a chitosan (CS)-based thermosensitive hydrogel to produce a VCM-nanoparticle (NPs)/Gel local drug delivery system. (dovepress.com)
  • Thermosensitive chitosan-gelatin-glycerol phosphate hydrogel as a controlled release system of ferulic acid for nucleus pulposus regeneration. (channel969.com)
  • Fungal Carboxymethyl Chitosan-Impregnated Bacterial Cellulose Hydrogel as Wound-Dressing Agent. (bvsalud.org)
  • We developed hydrogels by impregnating fungal-derived carboxymethyl chitosan to BC fiber networks using a simple solution immersion method . (bvsalud.org)
  • The reported multifunctional NPs hydrogel system for local antibiotic delivery (VCM-NPs/Gel) showed bone regeneration promotion and anti-infection properties, demonstrating significant potential as a scaffold for effective treatment of osteomyelitis. (dovepress.com)
  • Multifunctional hydrogels are a class of materials offering new opportunities for interfacing living organisms with machines due to their mechanical compliance, biocompatibility, and capacity to be triggered by external stimuli. (ibecbarcelona.eu)
  • Future Market Insights Presents Hydrogel Contact Lenses M. (pharmiweb.com)
  • VALLEY COTTAGE, N.Y. - The Market report envelopes an all-in information of the Global Hydrogel Contact Lenses Market and the nature of the Market growth over the foreseeable period. (pharmiweb.com)
  • The report provides a comprehensive elaboration of the positives and negatives of the Global Hydrogel Contact Lenses Market with DROT and Porter's Five Forces analysis. (pharmiweb.com)
  • With SWOT analysis, the report offers detailed insights about different players operating within the Hydrogel Contact Lenses Market. (pharmiweb.com)
  • In addition, the analysts of the report have served the qualitative and quantitative scrutinizing of different micro- and macro-economic factors influencing the Global Hydrogel Contact Lenses Market. (pharmiweb.com)
  • The COVID -19 pandemic has put forth a demanding situation for players in Hydrogel Contact Lenses Market. (pharmiweb.com)
  • The Hydrogel Contact Lenses Market report examines the consumption patter of each segment and the factors affecting the pattern. (pharmiweb.com)
  • The Hydrogel Contact Lenses Market report helps the readers grasp the changing trend in the industry supply chain, manufacturing techniques and expenses, and current scenario of the end uses in the Global Hydrogel Contact Lenses Market. (pharmiweb.com)
  • All the players running in the Global Hydrogel Contact Lenses Market are elaborated thoroughly in the Hydrogel Contact Lenses Market report on the basis of proprietary technologies, distribution channels, industrial penetration, manufacturing processes, and revenue. (pharmiweb.com)
  • In addition, the report examines R&D developments, legal policies, and strategies defining the competitiveness of the Hydrogel Contact Lenses Market players. (pharmiweb.com)
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  • What are the opportunities available for players operating in the Global Hydrogel Contact Lenses Market? (pharmiweb.com)
  • Which trends have the maximum impact on the growth of the Global Hydrogel Contact Lenses Market? (pharmiweb.com)
  • Why region leads the Global Hydrogel Contact Lenses Market? (pharmiweb.com)
  • What are the drivers and restraints affecting the Market size of the Global Hydrogel Contact Lenses Market? (pharmiweb.com)
  • A to Z of each player - positives & negatives, current status, future developments - of the Global Hydrogel Contact Lenses Market. (pharmiweb.com)
  • Detailed information regarding the trends influencing the growth of the Global Hydrogel Contact Lenses Market. (pharmiweb.com)
  • In-depth assessment on the utilization of Hydrogel Contact Lenses in each end use industry. (pharmiweb.com)
  • Historical data and future growth outlook of the Global Hydrogel Contact Lenses Market. (pharmiweb.com)
  • Herein we report a porous hydrogel composite comprising an agarose network and porous growing mix particle (GMP) fillers. (astrobiology.com)
  • Herein, we describe the development of porous hydrogel tubes fabricated through a two-step polymerization process with an intermediate microsphere phase that provides macroscale porosity (66.5%) for cell infiltration. (escholarship.org)
  • Quantitative results on the mean-squared displacement and the van Hove displacement distributions of NPs show that all NPs entrapped in the smart hydrogels undergo subdiffusion at both low and high temperatures. (rsc.org)
  • Biomedical applications of hydrogels: a review of patents and commercial products. (bruker.com)
  • 8,9 3D printing of nanocellulose hydrogels is being used in biomedical applications to support living cell growth for tissue engineering, implants, and cardiovascular devices. (cdc.gov)
  • The use of γ-PGA allowed the researchers to incorporate an anti-cancer drug (doxorubicin), magnetic nanoparticles, and magnetic resonance imaging probes into the hydrogel. (bruker.com)
  • Understanding the drug release kinetics and corresponding transport mechanisms of nanoparticles (NPs) in a thermoresponsive hydrogel network is the key to the successful design of smart drug delivery systems. (rsc.org)
  • Thus, the inorganic nanoparticles incorporated into a polymer matrix provide novel functionalities to hydrogels and tunable properties. (novapublishers.com)
  • Furthermore, when highly concentrated, collagen is extremely viscous at room temperature, which makes preparation and delivery of collagen-based hydrogels difficult. (bruker.com)
  • A hydrogel is a three-dimensional (3D) network of hydrophilic polymers that can swell in water and hold a large amount of water while maintaining the structure due to chemical or physical cross-linking of individual polymer chains. (penelopethemovie.com)
  • Many hydrogels are polymers of carboxylic acids. (penelopethemovie.com)
  • Hydrogels are polymers with a cross-linked network which is composed of up to 90% water. (penelopethemovie.com)
  • These types of polymers were first developed as hydrogels in the 1960s (Wichterle and Lim, 1960), having earlier been discovered by DuPont (du Pont de Nemours, 1936). (penelopethemovie.com)
  • We construct a mesoscopic model of rigid NPs entrapped in a hydrogel network in an aqueous solution, where the hydrogel network is formed by cross-linked semiflexible polymers of thermoresponsive poly( N -isopropylacrylamide) (PNIPAM). (rsc.org)
  • The polymers are subsequently used in dental sealants, composites and adhesives, bone composite materials, powder coatings, hydrogel lenses, and food contact material. (who.int)
  • In this paper, we introduce a new simple yet effective strategy to form "hydrogel skins" on polymer-based medical devices with arbitrary shapes. (imechanica.org)
  • Hydrogel skins can convert any surface of polymer devices into robust, wet, soft, slippery, antifouling, and ionically conductive without affecting the original properties and geometries. (imechanica.org)
  • Hydrogels are crosslinked hydrophilic polymer networks 49-51 that have attracted many fields of recent research, including the making of sensors. (criterionessays.com)
  • The authors used poly(γ-glutamic acid) (γ-PGA), a multifaceted anionic polymer electrolyte in order to modify the collagen hydrogel. (bruker.com)
  • The possible treatment uses the injection of a natural and biodegradable material to create a viscous hydrogel - a water-absorbing crosslinked polymer structure - that opens an alternate pathway for excess fluid to leave the eye. (medtecchina.com)
  • Hydrogels can be obtained by radiation technique in a few ways, including irradiation of solid polymer, monomer (in bulk or in solution), or aqueous solution of polymer. (penelopethemovie.com)
  • For a coil state, the transport of NPs in the hydrogels can be enhanced by decreasing the matrix porosity of the polymer network and NPs' size. (rsc.org)
  • In this study, varying concentrations of linear pNIPAAM have been incorporated for the first time into a thermo-responsive polymeric ionic liquid (PIL) hydrogel, namely tributyl-hexyl phosphonium 3-sulfopropylacrylate (P-SPA), to produce semi-interpenetrating polymer networks. (mdpi.com)
  • Report findings suggest that rising prevalence of chronic wounds, increasing evidence-based therapies for the same, surging diabetic population, along with growing incidence of venous leg ulcers as well as pressure ulcers are propelling global hydrogel dressing market expansion. (ibmag.com)
  • However, the unsuitability of hydrogels for moist wounds that can develop infections since they cannot absorb huge amounts of fluids, as well as their limited mechanical strength and susceptibility to tearing, because of which patients find it challenging to change their own bandages are some factors posing as a threat to market development in the ensuing years. (ibmag.com)
  • Gentell Hydrogel Ag Silver Antimicrobial Wound Gel is a unique wound care dressing designed for the treatment of wounds. (mountainside-medical.com)
  • We tested the effectiveness of keratin-based hydrogels (termed "keratose") loaded with ciprofloxacin to inhibit infection and support healing when topically administered to porcine excision wounds infected with Pseudomonas aeruginosa . (nih.gov)
  • Using a porcine excisional wound model, 10 mm full-thickness wounds were inoculated with 10 6 colony-forming units of P. aeruginosa and treated on days 1 and 3 postinoculation with ciprofloxacin-loaded keratose hydrogels. (nih.gov)
  • Ciprofloxacin-loaded keratose hydrogels reduced the amount of P. aeruginosa in the wound bed by 99.9% compared with untreated wounds on days 3, 7, and 11 postinjury. (nih.gov)
  • By day 11, wounds treated with ciprofloxacin-keratose hydrogels contained collagen-rich granulation tissue and myofibroblasts. (nih.gov)
  • Wounds treated with ciprofloxacin-loaded keratose hydrogels exhibited a transient increase in macrophages in the wound bed at day 7 postinjury that subsided by day 11. (nih.gov)
  • Stanford researchers are working on a hydrogel that may help mend damaged cartilage. (nbcbayarea.com)
  • After six months, Gold's research found patients treated with hydrogel had less pain and more healthy cartilage filled the hole compared to the traditional approach. (nbcbayarea.com)
  • These DN hydrogels were the first to be identified with mechanical properties resembling biological structures such as cartilage. (livescience.com)
  • The search for high quality implants initiated the research on cartilage replacement by hydrogels, which should assume the role of contact and friction in the joint implants. (anton-paar.com)
  • Here we show the contribution of tribology, surface charge, and nanoindentation for characterization of polyvinyl alcohol hydrogel and porcine articular joint cartilage. (anton-paar.com)
  • Hydrogels are considered as potential candidates for cartilage replacement because they are biocompatible and have mechanical properties similar to the joint cartilage [3] . (anton-paar.com)
  • In 2013, Professor Marcel Karperien asked her to join his group to work on the hydrogel aiming to solve cartilage problems. (liof.nl)
  • In this study, we aimed to evaluate the micromolded nonadhesive hydrogel (MicroTissues®) for spheroid compaction (2-day culture) and spontaneous chondrogenesis (21-day culture) using cartilage progenitors cells (CPCs) from human nasal septum without chondrogenic stimulus. (hindawi.com)
  • To the best of our knowledge, this is the first time in the scientific literature that human CPC spheroids were formed by micromolded nonadhesive hydrogel, achieving a successful scaffold-free cartilage engineering without chondrogenic stimulus (low cost). (hindawi.com)
  • On the other hand, hydrogels, commonly used in scaffold-based cartilage tissue engineering, are responsible to impair cell-cell interaction [ 11 ]. (hindawi.com)
  • AquaSite® Amorphous Hydrogel Dressing is a glycerine-based hydrogel, specifically formulated to provide a moist wound healing environment. (woundsource.com)
  • Gentell Hydrogel Ag Silver Antimicrobial Wound Gel contains Silver Sulfadiazine which decreases the bacterial load of gram-positive bacteria and gram-negative bacteria. (mountainside-medical.com)
  • Gentell Hydrogel Ag Silver Antimicrobial Wound Gel Dressing Ointment is for external use only. (mountainside-medical.com)
  • To purchase Gentell Hydrogel Ag Silver Antimicrobial Wound Gel and any of our other advanced wound care products, simply place your order online through our website. (mountainside-medical.com)
  • Ciprofloxacin-loaded keratose hydrogels displayed decreased wound contraction and reepithelialization at day 7 postinjury. (nih.gov)
  • Here, we show that ciprofloxacin-loaded keratose hydrogels inhibit cutaneous wound infection without interfering with key aspects of the healing process including granulation tissue deposition and remodeling. (nih.gov)
  • Therefore, CMCS-BC hydrogels can be considered suitable for antibacterial wound dressing applications. (bvsalud.org)
  • Superabsorbent sodium polyacrylate polymeric hydrogels that retain large amounts of liquids are used in disposable diapers, sanitary napkins, and other applications. (penelopethemovie.com)
  • INTRODUCTION Hydrogels are three-dimensional, hydrophilic, polymeric networks capable of absorbing large amounts ofwater or biological fluids. (penelopethemovie.com)
  • Conducted a thorough literature review on polymeric hydrogels applied for water treatment - wrote and published a review paper based on this. (europa.eu)
  • Inside the eye, the material chemically crosslinks to form the hydrogel, which holds open a channel in the SCS that allows aqueous humor from within the eye to drain out of the eye through the alternative pathway. (medtecchina.com)
  • They were not cross-linked in aqueous condition, which defines hydrogels. (penelopethemovie.com)
  • This study aims to determine the effects of transurethral polyacrylamide hydrogel injection in patients considered ineligible for midurethral sling surgery. (nih.gov)
  • In this prospective observational study, 81 patients received treatment with transurethral polyacrylamide hydrogel injection. (nih.gov)
  • In patients considered ineligible for midurethral sling surgery, transurethral injection with polyacrylamide hydrogel may alleviate urinary incontinence symptoms. (nih.gov)
  • Rejuvenate dull complexions with the Erno Laszlo Detoxifying Hydrogel Mask . (skinstore.com)
  • Replenish and brighten dry, aging skin with the Prosana® Cellulose Hydrogel Sheet Mask. (universalcompanies.com)
  • This mask is made from a unique 100% hydrogel material. (well.ca)
  • The panel identified the use of Gelesis100 oral superabsorbent hydrogel as a knowledge gap. (bvsalud.org)
  • By allowing the controlled release of a therapeutic agent over time, this hydrogel may allow doctors to hit the tumor with just the right amount of drug, sparing the patients' healthy tissues. (bruker.com)
  • In terms of raw materials, the natural segment of worldwide hydrogel dressing industry is poised to grow significantly over the forecast duration. (ibmag.com)
  • Which raw material category is slated to contribute significantly to worldwide hydrogel dressing market earnings? (ibmag.com)
  • By varying the temperature crossing the lower critical solution temperature of PNIPAM, we can significantly change the hydrogel network characteristics. (rsc.org)
  • Axon density within the hydrogel tubes (1744 axons/mm 2 ) was significantly increased more than 3-fold compared to the control (456 axons/mm 2 ), with approximately 30% of axons within the tube myelinated. (escholarship.org)
  • Finally, the hydrogel composite supported microgreen growth satisfyingly under simulated microgravity despite some morphological changes. (astrobiology.com)
  • Also, the Japanese researchers taught me the techniques for measuring the mechanical properties of hydrogels, such as tear tests to calculate toughness and tensile tests to study fracture properties. (livescience.com)
  • To this end, hydrogels are widely investigated as they have mechanical properties similar to native soft tissues and can be formed in situ to conform to a defect. (escholarship.org)
  • Natural melanin/alginate hydrogels achieve cardiac repair through ros scavenging and macrophage polarization. (channel969.com)
  • Absorbable hydrogel spacer use in prostate radiotherapy: A comprehensive review of phase 3 clinical trial published data. (bostonscientific.com)
  • A cylindrical phantom, resembling average human neck, was prepared by using hydrogel sheets containing vinyl and polysaccharide. (who.int)
  • The antibacterial activity of CMCS-BC hydrogels is shown using the CFU method against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). (bvsalud.org)
  • The next step, the researchers said, would be using integrin-binding molecules with other hydrogel technologies that have shown promise for long-term functional recovery after stroke, but in which newly grown blood vessels were not robust. (scitechdaily.com)
  • NMR technology allowed the researchers to determine the photothermal capabilities of this hydrogel both in vitro and in vivo . (bruker.com)
  • In animal trials, the team of Nanjing University researchers found that the hydrogel restored lost bodily function and helped the animals heal faster, according to research published Wednesday in the journal ACS NANO. (impactlab.com)
  • Researchers from The University of Manchester and Harvard University have collaborated on a pioneering project in bioengineering, producing metal-free, hydrogel electrodes that flex to fit the complex shapes inside the human body. (manchester.ac.uk)
  • Hydrogel is a white powder that, after mixing with water, cures in approximately five minutes to a moist, rubbery material. (polytek.com)
  • Hydrogel spacer prospective multicenter randomized controlled pivotal trial: Dosimetric and clinical effects of perirectal spacer application in men undergoing prostate image guided intensity modulated radiation therapy. (bostonscientific.com)
  • On the other hand, when used in air environments, water is inevitably lost from the hydrogels by evaporation, leading to the drying-out of hydrogels, which also causes degradation of the softness of hydrogels. (penelopethemovie.com)
  • Multispectral imaging allowed for the simultaneous analysis of hydrogel degradation and local vascularization. (ithera-medical.com)
  • In contrast to aggregates formed by external forces, spheroids are formed by self-assembling process using nonadherent hydrogel molds or platforms such as hanging-drop, 96-well plate, and recently micromolded nonadhesive hydrogels [ 7 , 8 ]. (hindawi.com)
  • Hydrogel is skin-safe and is useful for making quick, single-use molds. (polytek.com)
  • A variety of casting materials, like plaster, wax, and some polyurethane resins, can be poured directly into Hydrogel molds. (polytek.com)
  • this needs to be done right away as Hydrogel molds dry out very quickly and become unusable. (polytek.com)
  • The mucus layer is a hydrogel network that covers mucosal surfaces of the human body. (tu-berlin.de)
  • Mary Kay ® Hydrogel Eye Patches use the fun delivery system of hydrogel - water suspended in a gel matrix - to flood the eye area with benefits. (marykay.ca)
  • With hydrogel eye patches HYDROGEL PATCHES your morning will become really good! (viviennesabo.com)
  • The frictional properties of soft hydrogels in combination with the lubrication fluid can be measured using a rheometer with a tribological cell. (anton-paar.com)
  • Importantly, when elevated above body temperature, this hydrogel regains a fluid composition. (bruker.com)
  • Thus, the authors inferred that the hydrogel had entered a fluid state. (bruker.com)
  • These images are a random sampling from a Bing search on the term "Hydrogel Dressing. (fpnotebook.com)
  • The report on ' Global Hydrogel Dressing Market ' available with MarketStudyReport, states that global hydrogel dressing market is anticipated to witness a CAGR of 6.5% over the forecast period to amass notable returns by the year 2028. (ibmag.com)
  • Based on product type, the amorphous hydrogel dressing segment is expected to hold a considerable market share during the analysis timeframe. (ibmag.com)
  • What are the growth determinants for global hydrogel dressing market? (ibmag.com)
  • Which are the key players in global hydrogel dressing market? (ibmag.com)
  • A hollow microneedle less than a millimeter long is used to inject a droplet (about 50 microliters) of the hydrogel-precursor material. (medtecchina.com)
  • Scanning electron microscope (SEM) imaging showed the nitrogen-cured lens to have a surface typical of a hydrogel material, whereas the air-cured lens had regions of apparent phase separation. (bl.uk)
  • The hydrogel is essentially a porous and water-saturated material that can stretch, bend, and - most importantly - propagate neural signals. (impactlab.com)
  • Furthermore, implantation of hydrogel tubes enhanced functional recovery relative to control. (escholarship.org)
  • An in-situ refractive index method is applied to study the diffusion process of sucrose in hydrogels. (umn.edu)
  • Diffusion was monitored by recording the refraction of a laser beam when passing through a triangular hydrogel cell. (umn.edu)
  • L'impact des trois facteurs climatiques sur la diffusion de l' E - β -caryophyllène à partir de billes d'alginate a été évalué en utilisant un plan d'expérience de type Box-Behnken et un système en laboratoire de collecte des composés volatils. (ac.be)
  • Heureusement, cette augmentation de la teneur en eau n'a pas affecté la forme des billes, ce qui facilite le calcul du taux de diffusion de ce sémiochimique. (ac.be)
  • After swelling, the strength and toughness of hydrogels are drastically weakened. (penelopethemovie.com)
  • The CMCS-BC hydrogels were characterized using various characterization techniques such as XRD, FTIR , water contact angle measurements, TGA, and SEM to know the physiochemical properties. (bvsalud.org)
  • MPM Medical (Mesquite, TX) announced on Dec. 2, 2020 that it is voluntarily recalling one lot of Regenecare HA Hydrogel because of two customer complaints of visible contamination. (pharmtech.com)
  • To the mechanics community, we show that, for the first time in hydrogels, the fatigue threshold depends only on the covalent network, but not on the noncovalent interactions that provide dissipation. (imechanica.org)
  • Figure (9): The two types of conjugate chemistry for covalent attaching of DNA to hydrogel. (criterionessays.com)
  • Molecularly imprinted hydrogel layers with lectin-recognition sites were prepared on surface plasmon resonance (SPR) sensor chips via surface-initiated atom transfer radical polymerization (SI-ATRP) combined with molecular imprinting. (nature.com)
  • These results suggest that molecular recognition sites for the lectin were formed within the hydrogel layers by molecular imprinting. (nature.com)
  • Aligned hydrogel tubes guide regeneration following spinal cord injury. (escholarship.org)
  • Conversely, hydrogels can conform to any injury, but do not guide bi-directional regeneration. (escholarship.org)
  • In this work, we investigate the feasibility of a system of modular hydrogel tubes to promote bi-directional regeneration after spinal cord injury. (escholarship.org)