A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA.
Agents that promote the excretion of urine through their effects on kidney function.
A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.
A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Therapy with two or more separate preparations given for a combined effect.
A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
An angiotensin-converting enzyme inhibitor that is used to treat HYPERTENSION and HEART FAILURE.
An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Compounds with a BENZENE fused to IMIDAZOLES.
A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
A family of fused-ring hydrocarbons isolated from coal tar that act as intermediates in various chemical reactions and are used in the production of coumarone-indene resins.
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS.
Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)
A direct-acting vasodilator that is used as an antihypertensive agent.
A phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.
One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors) used for hypertension. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat.
An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
Heterocyclic compounds with SULFUR and NITROGEN in the ring. This term commonly refers to the BENZOTHIADIAZINES that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS and are used as DIURETICS.
A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Method in which repeated blood pressure readings are made while the patient undergoes normal daily activities. It allows quantitative analysis of the high blood pressure load over time, can help distinguish between types of HYPERTENSION, and can assess the effectiveness of antihypertensive therapy.
Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure.
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure.
Excretion of abnormally high level of CALCIUM in the URINE, greater than 4 mg/kg/day.
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC
A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS.
A nonselective beta-blocker used as an antihypertensive and an antianginal agent.
Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
An increase in the excretion of URINE. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.
A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
Compounds based on fumaric acid.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.

Low-dose combination therapy as first-line hypertension treatment for blacks and nonblacks. (1/504)

To assess the efficacy and safety of bisoprolol/6.25-mg hydrochlorothiazide (HCTZ), amlodipine, and enalapril in black and nonblack patients, data from two comparative studies were pooled and subgroup analyses performed. Both studies had similar designs and included all three active treatments. The second study also included a placebo group. Subjects (n = 541) with a sitting diastolic blood pressure of 95-114 mmHg were titrated to achieve a diastolic blood pressure < or = 90 mmHg. The studies included 114 blacks and 427 nonblacks. Results of an intention-to-treat analysis of mean change from baseline after 12 weeks of treatment showed the following: 1) blood pressure was significantly lowered by all three active drugs compared with baseline or placebo; 2) in blacks, bisoprolol/6.25-mg HCTZ resulted in significantly greater reductions of systolic and diastolic blood pressure than enalapril or placebo, but was not significantly different from amlodipine; 3) in nonblacks, bisoprolol/6.25-mg HCTZ resulted in significantly greater reduction of diastolic blood pressure than amlodipine, enalapril, or placebo. The placebo-corrected change in blood pressure was greater for blacks than whites on the bisoprolol/6.25-mg HCTZ combination, but this was not statistically significant. Bisoprolol/6.25-mg HCTZ controlled diastolic blood pressure to < or = 90 mmHg in significantly more patients than enalapril or placebo in blacks and nonblacks. The difference in control rates was not significant versus amlodipine. The incidence of drug-related adverse events was similar between treatments; however, bisoprolol/6.25-mg HCTZ had a lower discontinuation rate due to lack of blood pressure control or adverse experiences in both blacks and nonblacks.  (+info)

Drug-induced hyponatraemia in psychogenic polydipsia. (2/504)

Two patients with psychogenic polydipsia developed hyponatraemia, one in association with administration of hydrochlorothiazide and the other with that of tolbutamide. It is suggested that the increased fluid intake in such patients may make them more susceptible to the development of hyponatraemia from thiazide or sulphonylurea compounds.  (+info)

Inhibition of carbonic anhydrase accounts for the direct vascular effects of hydrochlorothiazide. (3/504)

Hydrochlorothiazide has been shown to exert direct vasodilator effects by activation of calcium-activated potassium (KCa) channels in human and guinea pig isolated resistance arteries. Since hydrochlorothiazide binds to and inhibits the enzyme carbonic anhydrase and because KCa channel activation is pH sensitive, we investigated the role of intracellular and extracellular carbonic anhydrase in the vascular effects of thiazide diuretics. Small arteries were isolated from guinea pig mesentery and studied by use of a microvascular myograph technique. In some experiments, tone and intracellular pH (pHi) were measured simultaneously with 2', 7'-bis(2-carboxyethyl)-5(6)'-carboxyfluorescein (BCECF-AM). Bendroflumethiazide, a thiazide diuretic with minimal inhibitory effects on carbonic anhydrase, had little effect on noradrenaline-induced tone (16+/-8% relaxation) compared with hydrochlorothiazide (74+/-12% relaxation). In contrast to hydrochlorothiazide, the action of bendroflumethiazide was unaffected by 100 nmol/L charybdotoxin, a selective blocker of KCa channels. All inhibitors of carbonic anhydrase relaxed noradrenaline-induced tone in a concentration-dependent manner, and this effect was blocked by charybdotoxin. Hydrochlorothiazide and the inhibitors of carbonic anhydrase failed to relax tone induced by a depolarizing potassium solution. Acetazolamide and hydrochlorothiazide increased pHi by 0.27+/-0.07 and 0.21+/-0.04, respectively, whereas bendroflumethiazide had a much smaller effect: 0.06+/-0.03. The rise in pHi induced by any agent was not inhibited by charybdotoxin. The vasorelaxant effect of hydrochlorothiazide is shared by other inhibitors of carbonic anhydrase. Inhibitors of carbonic anhydrase, but not bendroflumethiazide, cause intracellular alkalinization, which is associated with KCa channel opening. These data suggest that the vasodilator effect of thiazide diuretics results primarily from inhibition of vascular smooth muscle cell carbonic anhydrase, which results in a rise in pHI, leading to KCa channel activation and vasorelaxation.  (+info)

Treatment of nephrogenic diabetes insipidus with hydrochlorothiazide and amiloride. (4/504)

Nephrogenic diabetes insipidus (NDI) is characterised by the inability of the kidney to concentrate urine in response to arginine vasopressin. The consequences are severe polyuria and polydipsia, often associated with hypertonic dehydration. Intracerebral calcification, seizures, psychosomatic retardation, hydronephrosis, and hydroureters are its sequelae. In this study, four children with NDI were treated with 3 mg/kg/day hydrochlorothiazide and 0.3 mg/kg/day amiloride orally three times a day for up to five years. While undergoing treatment, none of the patients had signs of dehydration or electrolyte imbalance, all showed normal body growth, and there was no evidence of cerebral calcification or seizures. All but one had normal psychomotor development and normal sonography of the urinary tract. However, normal fluid balance was not attainable (fluid intake, 3.8-7.7 l/m2/day; urine output, 2.2-7.4 l/m2/day). The treatment was well tolerated and no side effects could be detected. Prolonged treatment with hydrochlorothiazide/amiloride appears to be more effective and better tolerated than just hydrochlorothiazide. Its efficacy appears to be similar to that of hydrochlorothiazide/indomethacin but without their severe side effects.  (+info)

Regulation of 11beta-hydroxysteroid dehydrogenase type 2 by diuretics and the renin-angiotensin-aldosterone axis. (5/504)

In the kidney and colon 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) inactivates cortisol to cortisone, thereby protecting the non-selective mineralocorticoid receptor from cortisol. Deficiency of 11beta-HSD2 results in cortisol-mediated sodium retention and hypertension, suggesting that the physiological regulation of 11beta-HSD2 in mineralocorticoid target tissues may be important in modulating sodium homoeostasis and blood pressure control. Using the human epithelial colon cell line SW-620, reverse transcriptase-polymerase chain reaction and enzyme kinetic analysis indicated expression of only 11beta-HSD2 (Km for cortisol 66 nmol/l). Bradykinin (10(-8) to 10(-12) mol/l), frusemide (10(-4) to 10(-9) mol/l), benzamiloride hydrochloride (10(-5) to 10(-10) mol/l) and atrial natriuretic peptide (10(-6) to 10(-10) mol/l) had no effect on 11beta-HSD2 expression. Using a range of concentrations of angiotensin II (2x10(-8) to 2x10(-5) mol/l) a significant reduction in activity was seen but only at supra-physiological concentrations, [e.g. 2x10(-6) mol/l at 4 h pretreatment: 36.7+/-2.0 pmol cortisone. h-1.mg-1 (mean+/-S.E.M.) compared with 45.1+/-1.7 pmol.h-1.mg-1 in control; P<0.05]. The angiotensin-converting enzyme inhibitors captopril, enalapril, lisinopril, perindopril, quinapril and trandolapril at 10(-7) mol/l, but not fosinopril, significantly increased 11beta-HSD2 activity after pretreatment for 16 or 24 h (P<0.05-P<0.01 compared with control). No effects were seen at 4 h pretreatment. Hydrochlorothiazide (10(-7) mol/l) significantly decreased 11beta-HSD2 activity (P<0.05 compared with control) at 4 h pretreatment. Commonly used diuretics, atrial natriuretic peptide and physiological concentrations of angiotensin II and bradykinin do not alter 11beta-HSD2 activity. In contrast, a series of angiotensin-converting enzyme inhibitors significantly increase 11beta-HSD2 activity in vitro. This may explain how intrarenal infusions of angiotensin-converting enzyme inhibitors increase renal sodium excretion independent of circulating concentrations of angiotensin II. The interaction between angiotensin-converting enzyme inhibitors and 11beta-HSD2 may be an additional mechanism by which the former can lower blood pressure.  (+info)

Optimization of urinary FDG excretion during PET imaging. (6/504)

Accumulation of fluorodeoxyglucose (FDG) activity in the urine interferes with the visualization of pelvic and, sometimes, abdominal abnormalities. Although this is a major problem, there are few data on the physiological variables affecting FDG urinary excretion that are critical to minimizing urinary FDG interference during PET imaging. METHODS: The excretion of FDG in urine was determined during 90 min in four groups of rats (n = 24) under the following conditions: normal, hydrated, hydrochlorothiazide treated and phlorizin treated. FDG clearance rates were measured in both normal and phlorizin-treated animals and compared with the glomeruler filtration rate measured with 99mTc-diethylenetriamine pentaacetic acid. We measured FDG excretion in 10 patients who had no known renal disease and were undergoing PET scanning (divided into two groups: hydrated and dehydrated) to relate the animal data to humans. RESULTS: The hydrated and phlorizin-treated animals had the highest excretion of FDG (39.68+/-5.00 % injected dose (%ID) and 45.64+/-9.77 %ID, respectively). Animals given the hydrochlorothiazide had the highest urinary volume, but the percentage excreted was comparable with the normal rats. Measurement of the clearance of FDG in animals before and after the administration of phlorizin determined the amount of FDG reabsorbed in the proximal tubules to be 56%+/-9.15%. The hydrated patients had a higher excretion of FDG than dehydrated patients (16.98+/-1.99 %ID versus 14.27+/-1.00 %ID, P < 0.021), and the volume of urine voided was significantly higher (P < 0.020). CONCLUSION: Hydrochlorothiazide increases urine volume without enhancing FDG excretion. The hydration of patients before PET scanning may lead to more FDG reaching the bladder. Reduction of bladder activity by more frequent voiding facilitated by increased urine volume in hydrated patients may be offset by increased delivery of FDG to the bladder. A preferable means of increasing urinary volume without increasing delivery of FDG to the bladder may be the use of a diuretic.  (+info)

Effects of aging and antihypertensive treatment on aortic internal diameter in spontaneously hypertensive rats. (7/504)

The effect of antihypertensive treatment on the development of large-artery remodeling in young animals has been widely studied, but reversal of established changes in older hypertensive animals has been largely ignored, although the latter represents a better paradigm for the human condition. We studied the effect of treatment with captopril plus hydrochlorothiazide, from 3 months onward, on geometry and wall stress of the thoracic aorta of adult (9 months, maturation) and old (15 months, senescence) spontaneously hypertensive rats; normotensive Wistar-Kyoto rats were used as controls. At 3 months of age, blood pressure, medial cross-sectional area, and internal diameter were higher in spontaneously hypertensive rats than in Wistar-Kyoto rats. In both strains, medial cross-sectional area and lumen diameter increased during maturation; there was little change with senescence. Changes in blood pressure were minor. Because medial hypertrophy failed to compensate for the wider lumen and higher intraluminal pressure in spontaneously hypertensive rats, medial stress was higher in these rats than in Wistar-Kyoto rats. Captopril plus hydrochlorothiazide rapidly lowered blood pressure and medial cross-sectional area. Despite a marked fall in blood pressure, the internal diameter of the thoracic aorta of treated animals was similar to that of untreated animals after 6 months of treatment and started to fall only after the animals had been treated for 1 year. Thus, under treatment with captopril plus hydrochlorothiazide, medial stress remained elevated, even after very-long-term treatment, because medial cross-sectional area was not adapted to internal diameter. We suggest that some changes in large-artery structure associated with hypertension and aging, such as the increase in diameter, take considerable time to regress after blood pressure is lowered, and this may explain why, despite treatment, wall stress remains elevated.  (+info)

Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics. (8/504)

AIMS: Fosinoprilat, the active product of fosinopril, is eliminated by an hepatic pathway in addition to the renal pathway shared by other angiotensin converting enzyme inhibitors (ACEIs). This study aimed to determine whether impaired renal function affects the pharmacokinetics and pharmacodynamics of a combination of fosinopril and hydrochlorothiazide (HCTZ). METHODS: The study had a parallel-group design comparing patients with renal impairment and body-mass-index-matched normal controls. The study was done in a University clinic in 13 patients with renal impairment (mean creatinine clearance 55.7+/-15.6 ml min-1 1.73 m-2 ) and 13 age-, sex-, and body-mass-index-matched normal controls (mean creatinine clearance 102.4+/-8.9 ml min-1 1.73 m-2 ). All patients and normal controls received fosinopril sodium 20 mg and HCTZ 12.5 mg as a daily oral administration on days 1-5. Non-compartmental pharmacokinetic parameters of fosinoprilat and HCTZ were determined from blood and urine samples obtained over 48 h starting on Day 1 (single dose) and Day 5 (steady state): maximum serum concentration (Cmax ), time to maximum serum concentration (tmax ), area under the serum concentration-time curve during the dosing interval (AUC), cumulative urinary excretion (CUE) and the accumulation index (AI; ratio of AUC-day 5/AUC-day 1). Pharmacodynamic parameters were also measured over 24 h on day 1 and over 48 h on day 5: serum ACE activity and arterial blood pressure. RESULTS: Fosinoprilat pharmacokinetic parameters on day 1 in renally impaired vs normal patients: Cmax=387+/-0.19 vs 324+/-0.25 ng ml-1 (P=0.07); tmax=3.5 vs 3.0 h (P=0.58); AUC=3510+/-0.29 vs 2701+/-0.35 ng ml-1 h (P=0. 072); CUE=5.08+/-2.70 vs 7.40+/-2.56% (P=0.009). Fosinoprilat parameters on day 5: Cmax=517+/-0.40 vs 357+/-0.19 ng ml-1 (P=0. 007); tmax=3.0 vs 3.0 h (P >0.99); AUC=4098+/-0.43 vs 2872+/-0.30 ng ml-1 h (P=0.027); CUE=6.81+/-3.53 vs 8.10+/-2.80% (P=0.068). AI=1. 17+/-0.33 vs 1.06+/-0.23 (P=0.29). In both groups ACE inhibition and blood pressure response were similar over 24 h and slightly greater 48 h after last dosing. CONCLUSIONS: In renally impaired subjects fosinopril and HCTZ can be coadministered without undue increases in fosinoprilat concentrations or any clinically significant pharmacodynamic effects. This is probably due to the dual excretory pathways for fosinoprilat.  (+info)

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TY - JOUR. T1 - The effects of telmisartan alone or with hydrochlorothiazide on morning and 24-h ambulatory BP control. T2 - Results from a practice-based study (SURGE 2). AU - Parati, Gianfranco. AU - Bilo, Grzegorz. AU - Redon, Josep. PY - 2013/4. Y1 - 2013/4. N2 - Observational studies have shown that 24-h and morning ambulatory blood pressure (BP) control is low. This large-scale, practice-based study evaluated the effects of telmisartan 40 or 80 mg alone or in combination with hydrochlorothiazide (HCTZ) 12.5 mg on these BP parameters over 8 weeks; treatment was adjusted if clinic BP remained ≥140/90 mm Hg. A total of 863 patients were evaluated (baseline mean clinic BP, morning and 24-h ambulatory BP: 155±15/93±10 mm Hg, 137±15/83±11 mm Hg, 133±14/79±10 mm Hg, respectively; 68% were previously treated at baseline). Telmisartan with/without HCTZ significantly reduced the mean morning ambulatory BP (-8.2/-4.9 mm Hg), daytime ambulatory BP (-8.0/-4.7 mm Hg), 24-h ambulatory BP ...
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Hydrochlorothiazide does not usually affect normal blood pressure.. Hydrochlorothiazide affects the distal renal tubular ... HYDROCHLOROTHIAZIDE tablet. To receive this label RSS feed. Copy the URL below and paste it into your RSS Reader application. ... Hydrochlorothiazide was not genotoxic in vitro in the Ames mutagenicity assay of Salmonella typhimurium strains TA 98, TA 100, ... Hydrochlorothiazide had no adverse effects on the fertility of mice and rats of either sex in studies wherein these species ...
Hydrochlorothiazide is associated with an increased risk of nonmelanoma skin cancer, according to updates to the medications ... Hydrochlorothiazide (HCTZ) is associated with an increased risk of nonmelanoma skin cancer, and patients who take the drug ... Cite this: FDA Updates Hydrochlorothiazide Label to Include Nonmelanoma Skin Cancer Risk - Medscape - Aug 24, 2020. ...
Aliskiren/hydrochlorothiazide is a combination drug used to treat high blood pressure (hypertension). Learn about side effects ... Highlights for aliskiren-hydrochlorothiazide. Oral tablet. 1 Aliskiren/hydrochlorothiazide is a combination of two drugs in a ... aliskiren-hydrochlorothiazide May Interact with Other Medications. Oral tablet. Aliskiren/hydrochlorothiazide can interact with ... It comes in these strengths: 150 mg aliskiren/12.5 mg hydrochlorothiazide, 150 mg aliskiren/25 mg hydrochlorothiazide, 300 mg ...
HYDROCHLOROTHIAZIDE (me TOE proe lole; hye droe klor oh THYE a zide) is a combination of a beta-blocker and a diuretic. ... Hydrochlorothiazide, HCTZ; Metoprolol tablets. What is this medicine?. METOPROLOL; HYDROCHLOROTHIAZIDE (me TOE proe lole; hye ... an unusual or allergic reaction to hydrochlorothiazide, metoprolol, sulfa drugs, or other medicines, foods, dyes, or ...
Prescribing data from Medicares prescription drug benefit, known as Part D, was compiled and released by the Centers for Medicare and Medicaid Services, the federal agency that oversees the program. The data for 2015 includes more than 1.4 billion prescriptions written by nearly 1.4 million doctors, nurses and other providers. This database lists about 447,000 of those providers who wrote 50 or more prescriptions for at least one drug that year. More than three-fourths of these prescriptions went to patients 65 and older; the rest were for disabled patients. Methodology ». ...
How does triamterene-hydrochlorothiazide work with other drugs and supplements? Helpful and harmful triamterene- ...
Top prescribers for VALSARTAN-HYDROCHLOROTHIAZIDE. 1 2 3 4 5 … Next › Last » ...
Rate your experience with Sk-Hydrochlorothiazide oral on - WebMD including the side effects, drug interactions, effectiveness, ...
... irbesartan/hydrochlorothiazide) intended for persons living in Australia. ... The other active ingredient in ABISART HCTZ is hydrochlorothiazide which belongs to a class of medicines known as diuretics. ... Hydrochlorothiazide contained in this medicine could produce a positive analytical result in antidoping test. ... allergic to irbesartan or hydrochlorothiazide or to sulfonamide derived medicines. allergic to any of the ingredients listed at ...
... The products contain a trace amount of an unexpected impurity ... Valsartan and Hydrochlorothiazide 80/12.5MG Tablets, USP 90 Count. 1191191M. Aug-2018. ... Valsartan and Hydrochlorothiazide 80/12.5MG Tablets, USP 90 Count. 1191192M. Aug-2018. ... Valsartan and Hydrochlorothiazide 80/12.5MG Tablets, USP 90 Count. 1191193M. Aug-2018. ...
Medline Industries, Inc. All rights reserved. Advancing the Health of Healthcare is a trademark and Medline is a registered trademark of Medline Industries, Inc ...
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can ... What is hydrochlorothiazide and aliskiren?. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your ... If you become pregnant, stop taking this medicine and tell your doctor right away. Hydrochlorothiazide and aliskiren can cause ... What are the possible side effects of hydrochlorothiazide and aliskiren?. Get emergency medical help if you have signs of an ...
... is a combination medicine used to treat hypertension (high blood pressure). Lowering blood ... Hydrochlorothiazide is a thiazide diuretic (water pill). Lisinopril is in an ACE inhibitor (ACE stands for angiotensin ... Hydrochlorothiazide-Lisinopril. slide 1 of 44, Hydrochlorothiazide-Lisinopril,. 12.5 mg-10 mg, round, blue, imprinted with WW ... Hydrochlorothiazide-Lisinopril. slide 7 of 44, Hydrochlorothiazide-Lisinopril,. 12.5 mg-20 mg, round, white, imprinted with E ...
... contains a diuretic (water pill) and an angiotensin II receptor blocker (ARB). ... Hydrochlorothiazide and irbesartan may also be used for purposes not listed in this medication... ... Hydrochlorothiazide and irbesartan is a combination medicine used to treat high blood pressure (hypertension). ... Hydrochlorothiazide-Irbesartan. slide 1 of 11, Hydrochlorothiazide-Irbesartan,. 12.5 mg-150 mg, round, red, imprinted with 54 ...
a)Specifications. Each milliliter of solution contains 25 milligrams of hydrochlorothiazide. (b)Sponsor. See No. 050604 in § ...
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away. This medicine may cause dizziness, lightheadedness, or fainting, especially when you get up suddenly from a lying or sitting position. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. If you faint, call your doctor right away. Check with your doctor right away if you become sick while taking this medicine, especially if you have severe nausea, vomiting, or diarrhea that does not stop. These conditions may cause you to lose too much water and lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during ...
... hydrochlorothiazide and amiloride hydrochloride) intended for persons living in Australia. ... Hydrochlorothiazide, one of the active ingredients of Amizide, is a sulfur containing medicine. Therefore, if you are allergic ... Do not take Amizide if you are allergic to medicines containing either amiloride or hydrochlorothiazide or any of the ... Amizide contains a combination of two diuretics, amiloride hydrochloride and hydrochlorothiazide as the active ingredients. It ...
No se debe utilizar esta información para decidir si se debe tomar este medicamento o cualquier otro. Solamente el proveedor de atención médica tiene el conocimiento y la capacitación para decidir qué medicamentos son adecuados para un paciente específico. Esta información no recomienda ningún medicamento como seguro, eficaz o aprobado para tratar a ningún paciente o enfermedad. Es solamente un breve resumen de información general sobre este medicamento. NO incluye toda la información sobre los usos, las instrucciones, las advertencias, las precauciones, las interacciones, los efectos secundarios o los riegos posibles que podrían aplicarse a este medicamento. Esta información no constituye asesoramiento médico específico y no reemplaza la información que usted recibe de su proveedor de atención médica. Debe hablar con el proveedor de atención médica para obtener información completa sobre los riesgos y los beneficios de tomar este medicamento.. ...
Using this medicine while you are pregnant (especially in your second or third trimester) can harm your unborn baby. If you think you have become pregnant while using this medicine, tell your doctor right away. This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. Call your doctor right away if you have severe stomach pain (with or without nausea or vomiting). This could be a symptom of intestinal angioedema. Dizziness, lightheadedness, or fainting may also occur, especially when you get up from a lying or sitting position or if you have been taking a diuretic (water pill). Make sure you know how you react to the medicine before you drive, use machines, or do other things that could be dangerous if you ...
  • Does Capozide (captopril and hydrochlorothiazide/HCTZ) cause side effects? (medicinenet.com)
  • Capozide ( captopril and hydrochlorothiazide /HCTZ) is a combination of an angiotensin converting enzyme (ACE) inhibitor and a diuretic (water pill), used to treat high blood pressure ( hypertension ). (medicinenet.com)
  • What are the important side effects of Capozide (captopril and hydrochlorothiazide/HCTZ)? (medicinenet.com)
  • Hydrochlorothiazide (HCTZ) is associated with an increased risk of nonmelanoma skin cancer, and patients who take the drug should limit sun exposure and undergo regular skin cancer screening, according to updates to the medication's label. (medscape.com)
  • ABISART HCTZ tablets contain two medicines, irbesartan and hydrochlorothiazide. (news-medical.net)
  • The other active ingredient in ABISART HCTZ is hydrochlorothiazide which belongs to a class of medicines known as diuretics. (news-medical.net)
  • AVALIDE (irbesartan-hydrochlorothiazide) tablets are a combination of an angiotensin II receptor antagonist (AT 1 subtype), irbesartan, and a thiazide diuretic , hydrochlorothiazide (HCTZ). (rxlist.com)
  • Hyzaar combines a new kind of blood pressure medicine (prescribed alone as Cozaar) with an old-fashioned diuretic, hydrochlorothiazide (HCTZ). (peoplespharmacy.com)
  • Hydrochlorothiazide (HCTZ) is intended for people with edema (fluid retention) caused by congestive heart failure, kidney disorder, liver disease or steroid or hormone therapy. (sharecare.com)
  • Hydrochlorothiazide (HCTZ), a diuretic, increases the excretion of salt and water in the urine. (wholehealthmd.com)
  • Hydrochlorothiazide (HCTZ) has often been contrasted with chlorthalidone, but relatively little is known about HCTZ versus indapamide (INDAP). (ahajournals.org)
  • Hydrochlorothiazide may be abbreviated as HCTZ. (bingj.com)
  • Before taking hydrochlorothiazide (HCTZ) it's important that you and your doctor discuss your medical history and the benefits and risks of taking a thiazide diuretic. (sharecare.com)
  • hydrochlorothiazide (hctz) manufacturers and suppliers with contacts and product range are mentioned in the study. (marketpublishers.com)
  • Furthermore, hydrochlorothiazide (hctz) prices in regional markets can be found in the report with regards to countries and companies. (marketpublishers.com)
  • The report also focuses on hydrochlorothiazide (hctz) consumers by providing data on companies that use it. (marketpublishers.com)
  • Hydrochlorothiazide (HCTZ) (CAS 58-93-5) Market Research Report 2018 contents were prepared and placed on the website in December, 2018. (marketpublishers.com)
  • Please note that Hydrochlorothiazide (HCTZ) (CAS 58-93-5) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
  • Take hydrochlorothiazide exactly as directed. (medlineplus.gov)
  • Continue to take hydrochlorothiazide even if you feel well. (medlineplus.gov)
  • Your doctor may tell you not to take hydrochlorothiazide. (medlineplus.gov)
  • How should I take hydrochlorothiazide and aliskiren? (rexhealth.com)
  • Do not take hydrochlorothiazide and benazepril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). (adventisthealthcare.com)
  • Who should take hydrochlorothiazide? (sharecare.com)
  • I Take Hydrochlorothiazide: Do I Need to Take Potassium Supplements? (livestrong.com)
  • If you take hydrochlorothiazide, your doctor will most likely check your potassium levels frequently. (livestrong.com)
  • On November 8th, 2018 the FDA announced that Sandoz is recalling a single lot of Losartan/Hydrochlorothiazide Tablets 100mg/25mg at the consumer level due to an impurity detected in the recalled products. (express-scripts.com)
  • Based on the initial blood pressure response and/or losartan-hydrochlorothiazide side effects, the dosage may be increased or decreased. (wikipedia.org)
  • What is the dosage for valsartan/hydrochlorothiazide? (medicinenet.com)
  • Duration of diuretic activity and effective dosage range of the hydrochlorothiazide and triamterene components of DYAZIDE are similar. (bioportfolio.com)
  • What is the dosage of Amlodipine, Valsartan and Hydrochlorothiazide? (medindia.net)
  • Personal sleep that sucks is the before available fourfive doxycycline in hydrochlorothiazide and doxycycline my lip but its dosage it for anaerobic sine! (txpvietnam.com)
  • What is valsartan/hydrochlorothiazide? (medicinenet.com)
  • Valsartan / hydrochlorothiazide is a combination of two medications that is used to treat high blood pressure and congestive heart failure . (medicinenet.com)
  • The combination of valsartan and hydrochlorothiazide reduces blood pressure more that either drug alone. (medicinenet.com)
  • The FDA approved valsartan/hydrochlorothiazide in March 1998. (medicinenet.com)
  • What are the uses for valsartan/hydrochlorothiazide? (medicinenet.com)
  • Valsartan/hydrochlorothiazide is used for the treatment of blood pressure in patients with or without a history of congestive heart failure . (medicinenet.com)
  • What are the side effects of valsartan/hydrochlorothiazide? (medicinenet.com)
  • Side effect of valsartan/hydrochlorothiazide are the same as its individual components. (medicinenet.com)
  • The recommended starting dose of valsartan/hydrochlorothiazide is 80/12.5 to 160 mg/ 12.5 mg by mouth once daily. (medicinenet.com)
  • Which drugs or supplements interact with valsartan/hydrochlorothiazide? (medicinenet.com)
  • Valsartan/hydrochlorothiazide can increase lithium ( Lithobid , Eskolith) levels in the body. (medicinenet.com)
  • Valsartan/hydrochlorothiazide should be used with caution with nonsteroidal anti-inflammatory drugs ( NSAIDs ) like naproxen ( Naprosyn ), ibuprofen ( Motrin ), meloxicam ( Mobic ), and celecoxib ( Celebrex ) because they can worsen kidney function and lower water removing effects of valsartan/hydrochlorothiazide. (medicinenet.com)
  • Is valsartan/hydrochlorothiazide safe to take if I'm pregnant or breastfeeding? (medicinenet.com)
  • Valsartan/hydrochlorothiazide is not recommended for pregnant females. (medicinenet.com)
  • Valsartan/hydrochlorothiazide is not recommended for females who are breastfeeding because it may enter breast milk . (medicinenet.com)
  • What else should I know about valsartan/hydrochlorothiazide? (medicinenet.com)
  • Valsartan/hydrochlorothiazide is available as tablets of 40, 80, 160 and 320 mg. (medicinenet.com)
  • Valsartan/hydrochlorothiazide tablets should be stored between 15 C and 30 C (59 and 86 F). (medicinenet.com)
  • valsartan/hydrochlorothiazide is available in generic form. (medicinenet.com)
  • Valsartan and hydrochlorothiazide (Diovan HCT) is a combination of two prescription medicaiton used to treat high blood pressure. (medicinenet.com)
  • This study was conducted to compare the rate and extent of absorption of valsartan and hydrochlorothiazide following oral administration as a fixed dose combination tablet and concomitant administration of the individual drugs under fasting conditions in healthy Egyptian subjects. (clinicaltrials.gov)
  • Hydrochlorothiazide and valsartan is usually given after other blood pressure medicines have been tried without success. (wellspan.org)
  • Latest prescription information about Amlodipine, Valsartan and Hydrochlorothiazide. (medindia.net)
  • Why is Amlodipine, Valsartan and Hydrochlorothiazide Prescribed? (medindia.net)
  • When should Amlodipine, Valsartan and Hydrochlorothiazide not to be taken? (medindia.net)
  • Available doses are 5/160/12.5 mg, 10/160/12.5 mg, 5/160/25 mg, 10/160/25 mg and 10/320/25 mg amlodipine besylate/valsartan/hydrochlorothiazide. (medindia.net)
  • How should Amlodipine, Valsartan and Hydrochlorothiazide be taken? (medindia.net)
  • What are the warnings and precautions for Amlodipine, Valsartan and Hydrochlorothiazide? (medindia.net)
  • Losartan/hydrochlorothiazide , sold under the trade name Hyzaar among others, is a combination medication used to treat high blood pressure when losartan is not sufficient. (wikipedia.org)
  • Hydrochlorothiazide and aliskiren may also be used for purposes not listed in this medication guide. (rexhealth.com)
  • If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine). (rexhealth.com)
  • Our Aldoril (methyldopa and hydrochlorothiazide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • Since hydrochlorothiazide causes frequent urination, it is advised that the medication be taken in the morning or afternoon to avoid sleep disturbances during the night. (wisegeek.com)
  • The Food and Drug Administration has stated that because Losartan/Hydrochlorothiazide is used to treat serious medical conditions, patients taking a recalled medication should continue taking their medicine until they have an alternative therapy or new supply. (express-scripts.com)
  • However, grapefruit does not appear to affect hydrochlorothiazide, meaning you can consume grapefruit while taking this medication. (livestrong.com)
  • To understand why grapefruit does not interact with hydrochlorothiazide, you need to understand how this medication is eliminated from the body. (livestrong.com)
  • Although grapefruit will not increase your risk of developing side effects from hydrochlorothiazide, taking this medication along with any food, including grapefruit, can decrease its absorption, limiting its effectiveness. (livestrong.com)
  • Generic Microzide is a term used to identify all drugs that are identical to the brand-name medication based on the active ingredient called Hydrochlorothiazide that is efficient in reducing arterial pressure and in alleviation of the symptoms of some other conditions such as diabetes insipidus, nephrocalcinosis, osteoporosis, swelling, and others. (rxshop.md)
  • In this medication guide you can find the general recommendations on the therapy with Generic Hydrochlorothiazide but please consult a qualified specialist before you buy Microzide or its generic and start using it. (rxshop.md)
  • If you have diabetes, do not use hydrochlorothiazide and losartan together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna). (wellspan.org)
  • Generics deplete this and hydrochlorothiazide and lisinopril once the code medication, you will need more p-values. (duvalia.com)
  • Levitra is a prescription medication for the treatment of erectile dysfunction (ED) where to get hydrochlorothiazide . (xochiquetzal.nl)
  • A version combined with hydrochlorothiazide is available and, in 2018, it was the 54th most commonly prescribed medication in the United States, with more than 13 million prescriptions. (wikipedia.org)
  • Hydrochlorothiazide tablets are indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. (nih.gov)
  • Hydrochlorothiazide and aliskiren is a combination medicine used to treat high blood pressure (hypertension). (rexhealth.com)
  • AVALIDE ® (irbesartan-hydrochlorothiazide) tablets are indicated for the treatment of hypertension . (rxlist.com)
  • Bisoprolol was approved by the FDA in 1992 and is available by itself as Zebeta, while hydrochlorothiazide has been a mainstay of hypertension treatment for decades. (peoplespharmacy.com)
  • Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. (nih.gov)
  • In a randomized, double-blind trial, we assigned 11,506 patients with hypertension who were at high risk for cardiovascular events to receive treatment with either benazepril plus amlodipine or benazepril plus hydrochlorothiazide. (nih.gov)
  • The benazepril-amlodipine combination was superior to the benazepril-hydrochlorothiazide combination in reducing cardiovascular events in patients with hypertension who were at high risk for such events. (nih.gov)
  • ACCOMPLISH trial findings: combination benazepril-amlodipine or hydrochlorothiazide is effective for treating hypertension. (nih.gov)
  • In combination with hydrochlorothiazide, it is used in the treatment of hypertension. (fda.gov)
  • She had had hypertension, treated with hydrochlorothiazide (Hydrodiuril®), for 10 years. (annals.org)
  • Hydrochlorothiazide is a diuretic often used to treat hypertension and also edema, or fluid retention, and congestive heart failure. (livestrong.com)
  • After hypertension revolutionized the person of cz4t-p0ccurrent results in wwii, doxycycline and hydrochlorothiazide cystic dan times moved into the middel of discovering effects by period. (txpvietnam.com)
  • Dosages greater than 50mg/day are not usually needed when hydrochlorothiazide is given in conjunction with other drugs used for hypertension. (bingj.com)
  • Generic for Hydrodiuril* (Hydrochlorothiazide) is a water pill (diuretic) used to treat high blood pressure (hypertension). (internationaldrugmart.com)
  • Hydrochlorothiazide comes as a tablet, capsule, and solution (liquid) to take by mouth. (medlineplus.gov)
  • The standard starting dose for adults is one 25-mg captopril/15-mg hydrochlorothiazide tablet taken by mouth once per day. (healthline.com)
  • You'll take your aliskiren/hydrochlorothiazide oral tablet one time per day. (healthline.com)
  • A capsule of DYAZIDE is bioequivalent to a single entity 25-mg hydrochlorothiazide tablet and 37.5-mg triamterene capsule used in the double-blind clinical trial below (see Clinical Trials). (bioportfolio.com)
  • A total of 36 subjects were randomized to receive single oral dose of hydrochlorothiazide 50 mg tablet and 31 subjects completed both the periods of the study. (clinicaltrials.gov)
  • Mean blood pressures after dose adjustment were 131.6/73.3 mm Hg in the benazepril-amlodipine group and 132.5/74.4 mm Hg in the benazepril-hydrochlorothiazide group. (nih.gov)
  • Benazepril plus amlodipine reduced cardiovascular risk more than benazepril plus hydrochlorothiazide. (nih.gov)
  • If you are looking for the generic alternative to Tribenzor, please see: Olmesartan/Amlodipine/Hydrochlorothiazide - Generic. (doctorsolve.com)
  • Hydrochlorothiazide belongs to a class of drugs called thiazide diuretics. (healthline.com)
  • Amizide contains a combination of two diuretics, amiloride hydrochloride and hydrochlorothiazide as the active ingredients. (news-medical.net)
  • However, giving oral potassium pills along with thiazide diuretics negates the cost savings of hydrochlorothiazide over other diuretics. (livestrong.com)
  • Hydrochlorothiazide belongs to the class of medicines known as thiazide diuretics. (bingj.com)
  • The effects of hydrochlorothiazide indirectly lower the levels of serum potassium. (wikipedia.org)
  • NSAIDs may reduce the blood pressure lowering effects of hydrochlorothiazide. (medicinenet.com)
  • Avoid drinking alcohol, which can increase some of the side effects of hydrochlorothiazide. (cardiosmart.org)
  • What are the possible side effects of hydrochlorothiazide and irbesartan (Avalide)? (rxlist.com)
  • There are several common side effects of hydrochlorothiazide, a type of drug also called a thiazide diuretic, or water pill. (wisegeek.com)
  • Drinking alcohol can increase certain side effects of hydrochlorothiazide and spironolactone. (cardiosmart.org)
  • The diuretic and blood pressure lowering effects of hydrochlorothiazide may last six to 12 hours. (bingj.com)
  • Drug interactions to be aware of include lithium, agents increasing serum levels of potassium, and the use of hydrochlorothiazide with antidiabetic drugs both oral agents and insulin. (wikipedia.org)
  • tell your doctor and pharmacist if you are allergic to hydrochlorothiazide, 'sulfa drugs', penicillin, or any other drugs. (medlineplus.gov)
  • Captopril/hydrochlorothiazide is a combination of two drugs in a single form that work in different ways to treat high blood pressure. (healthline.com)
  • Captopril/hydrochlorothiazide is a combination of two drugs in a single form. (healthline.com)
  • There are many other drugs that can interact with hydrochlorothiazide. (cardiosmart.org)
  • Digoxin , lithium and non-steroidal anti-inflammatory drugs ( NSAIDs ) are just some of the drugs that might interfere with hydrochlorothiazide. (wisegeek.com)
  • These drugs are collectively referred to as Generic Microzide based on the brand name or Generic Hydrochlorothiazide coming from the name of the active substance used in the medications. (rxshop.md)
  • They prescribed effect for 10 medicines to hydrochlorothiazide and lisinopril loosen differences up so i can take nonparametric drugs. (duvalia.com)
  • Aldosterone: renal drugs can potentiate the hydrochlorothiazide and lisinopril atrial nitrates of sale reason herbs. (duvalia.com)
  • Hyzaar is the brand name of a combination medicine that contains the drugs losartan and hydrochlorothiazide . (everydayhealth.com)
  • Other drugs may interact with hydrochlorothiazide and moexipril, including prescription and over-the-counter medicines, vitamins, and herbal products. (everydayhealth.com)
  • Had history of allergy or hypersensitivity to hydrochlorothiazide or any other sulphonamide derived drugs. (clinicaltrials.gov)
  • Macleods Pharmaceuticals Limited is recalling one lot of Losartan Potassium/Hydrochlorothiazide combination tablets, a high blood pressure treatment. (consumeraffairs.com)
  • The gastrointestinal dan, doxycycline and hydrochlorothiazide although of longer name and consisting of a larger parasiet of passes, yielded the dysfunctional interactions. (txpvietnam.com)
  • tell your doctor and pharmacist if you are allergic to methyldopa, hydrochlorothiazide, sulfa medications, any other medications, or any of the ingredients in methyldopa and hydrochlorothiazide tablets. (medlineplus.gov)
  • Do not take Amizide if you are allergic to medicines containing either amiloride or hydrochlorothiazide or any of the ingredients listed at the end of this leaflet. (news-medical.net)
  • Unusual but serious reactions to hydrochlorothiazide include rashes which require medical attention, allergic reactions (anaphylaxis) that involve difficulty breathing and shock, changes in blood, increased blood sugar, and disturbances in the balance of electrolytes. (peoplespharmacy.com)
  • To the editor: We read with great interest the report of hydrochlorothiazide-induced allergic pneumonitis by Beaudry and Laplante ( Ann Intern Med 78:251-253, 1973). (annals.org)
  • When used to treat edema, hydrochlorothiazide may be taken daily or only on certain days of the week. (medlineplus.gov)
  • Hydrochlorothiazide tablets are indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. (nih.gov)
  • Hydrochlorothiazide tablets have also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure. (nih.gov)
  • Hydrochlorothiazide treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. (cardiosmart.org)
  • The combination of hydrochlorothiazide and spironolactone is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. (cardiosmart.org)
  • In some cases, hydrochlorothiazide is used to treat edema or high blood pressure in children. (sharecare.com)
  • To reduce fluid retention (edema), the usual recommended adult dose of hydrochlorothiazide is 25 mg to 200 mg daily, given in 1 to 3 divided doses. (medbroadcast.com)
  • Hydrochlorothiazide may be used to relieve edema and in the treatment of high blood pressure but may not be suitable for some people including those with sulfonamide allergies. (bingj.com)
  • It's important to tell your doctor about all over-the-counter and prescription medications, supplements and vitamins you are taking, before receiving hydrochlorothiazide to treat edema or high blood pressure. (sharecare.com)
  • Hydrochlorothiazide reduces the swelling of hands or feet (edema), as well as water retention in people with liver disease, kidney disease, and congestive heart failure. (internationaldrugmart.com)
  • This drug is a combination of two medicines in a single form: aliskiren and hydrochlorothiazide. (healthline.com)
  • Licorice can greatly increase potassium loss due to medicines such as hydrochlorothiazide. (peoplespharmacy.com)
  • Some foods and medicines can affect how lisinopril/hydrochlorothiazide works. (umm.edu)
  • Medicines that interact with hydrochlorothiazide may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with hydrochlorothiazide. (bingj.com)
  • Accord Healthcare Inc. is voluntarily recalling 1 lot of Hydrochlorothiazide Tablets USP, 12.5 mg, at the consumer level, due to a potential labeling mix-up. (pharmacytimes.com)
  • According to the company, the lot (PW05264) of 100-count bottles of Hydrochlorothiazide Tablets USP 12.5 mg has been found to contain 100 Spironolactone Tablets USP 25 mg. (pharmacytimes.com)
  • Accord's Hydrochlorothiazide Tablets USP 12.5 mg are light orange to peach colored, round, biconvex tablets debossed with H on one side and 1 on another side. (pharmacytimes.com)
  • Accord Healthcare Inc. Issues Voluntary Nationwide Recall of Hydrochlorothiazide Tablets USP 12.5 mg due to labeling mix-up [news release]. (pharmacytimes.com)
  • https://prnmedia.prnewswire.com/news-releases/accord-healthcare-inc-issues-voluntary-nationwide-recall-of-hydrochlorothiazide-tablets-usp-12-5-mg-due-to-labeling-mix-up-300702928.html?c=n. (pharmacytimes.com)
  • Accord Healthcare Inc. is voluntarily recalling One lot (Lot PW05264 - 46632 Bottles, NDC 16729-182-01) of Hydrochlorothiazide Tablets USP, 12.5 mg, to the consumer level. (fda.gov)
  • The exact mechanism of the antihypertensive effect of hydrochlorothiazide is not known. (bioportfolio.com)
  • Hydrochlorothiazide and irbesartan contains a diuretic (water pill) and an angiotensin II receptor blocker (ARB). (rexhealth.com)
  • Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. (rexhealth.com)
  • In addition to high blood pressure, hydrochlorothiazide is also used to treat other medical conditions, one of them being fluid retention. (wisegeek.com)
  • Hydrochlorothiazide is supplied as 25 mg and 50 mg tablets for oral use. (nih.gov)
  • AVALIDE is available for oral administration in film-coated tablets containing either 150 mg or 300 mg of irbesartan combined with 12.5 mg of hydrochlorothiazide. (rxlist.com)
  • Each capsule of DYAZIDE (hydrochlorothiazide and triamterene) for oral use, with opaque red cap and opaque white body, contains hydrochlorothiazide 25 mg and triamterene 37.5 mg, and is imprinted with the product name DYAZIDE and SB. (bioportfolio.com)
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  • Zestoretic tablets contain two active ingredients, lisinopril and hydrochlorothiazide. (netdoctor.co.uk)
  • The combination of lisinopril with hydrochlorothiazide is used when blood pressure has not been lowered sufficiently using lisinopril on its own. (netdoctor.co.uk)
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  • Hydrochlorothiazide is used alone or in combination with other medications to treat high blood pressure. (medlineplus.gov)
  • Hydrochlorothiazide controls high blood pressure but does not cure it. (medlineplus.gov)
  • The combination of methyldopa and hydrochlorothiazide is used to treat high blood pressure. (medlineplus.gov)
  • Hydrochlorothiazide is a diuretic (water pill) used for treating high blood pressure and accumulation of fluid. (medicinenet.com)
  • Captopril/hydrochlorothiazide is used to treat high blood pressure. (healthline.com)
  • For example, one of the ailments that hydrochlorothiazide is used to treat is high blood pressure . (wisegeek.com)
  • Bisoprolol/hydrochlorothiazide can control high blood pressure, but cannot cure it. (wholehealthmd.com)
  • Although grapefruit can be dangerous if it interacts with some medications, it does not appear to interact with hydrochlorothiazide, a diuretic often used to treat high blood pressure. (livestrong.com)
  • For the treatment of high blood pressure, the usual recommended adult dose of hydrochlorothiazide is 12.5 mg to 50 mg daily. (medbroadcast.com)
  • Hydrochlorothiazide is slightly soluble in water and freely soluble in sodium hydroxide solution. (rxlist.com)
  • Hydrochlorothiazide is slightly soluble in water. (bioportfolio.com)
  • Hydrochlorothiazide is a type of medicine called a thiazide diuretic. (netdoctor.co.uk)
  • It comes in these strengths: 150 mg aliskiren/12.5 mg hydrochlorothiazide, 150 mg aliskiren/25 mg hydrochlorothiazide, 300 mg aliskiren/12.5 mg hydrochlorothiazide, and 300 mg aliskiren/25 mg hydrochlorothiazide. (healthline.com)
  • Capozide tablets contain two active ingredients, captopril and hydrochlorothiazide. (netdoctor.co.uk)
  • The combination of captopril and hydrochlorothiazide is sometimes known as co-zidocapt. (netdoctor.co.uk)
  • If you have an allergy to fosinopril, hydrochlorothiazide, or any other part of this drug. (mskcc.org)
  • Do not use potassium supplements while you are taking hydrochlorothiazide and spironolactone. (cardiosmart.org)
  • These products could cause your potassium levels to get too high while you are taking hydrochlorothiazide and spironolactone. (cardiosmart.org)
  • Use of spironolactone tablets instead of hydrochlorothiazide tablets, poses the risk of contracting increased potassium levels in certain individuals, resulting in adverse events that range from limited health consequences to life-threatening situations in certain individuals. (pharmacytimes.com)
  • With continued use of hydrochlorothiazide and depletion of sodium, compensatory mechanisms tend to increase this exchange and may produce excessive loss of potassium, hydrogen, and chloride ions. (bioportfolio.com)
  • By inhibiting the distal tubular exchange mechanism, triamterene maintains or increases the sodium excretion and reduces the excess loss of potassium, hydrogen and chloride ions induced by hydrochlorothiazide. (bioportfolio.com)
  • Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and moexipril, unless your doctor has told you to. (everydayhealth.com)
  • Hypokalemia from hydrochlorothiazide can often be prevented by eating a banana a day, which supplies 1 meQ of potassium, according to Family Practice Notebook. (livestrong.com)
  • Captopril/hydrochlorothiazide is available as a generic drug. (healthline.com)
  • Generic hydrochlorothiazide is available. (bingj.com)
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  • If you become pregnant while taking hydrochlorothiazide, call your doctor immediately. (medlineplus.gov)
  • If you get pregnant while taking captopril/hydrochlorothiazide, tell your doctor right away. (healthline.com)
  • Enalapril-Hydrochlorothiazide combines an Angiotensin-Converting Enzyme (ACE) Inhibitor and thiazide diuretic. (patientslikeme.com)
  • There are no evaluations for Enalapril-Hydrochlorothiazide. (patientslikeme.com)
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  • B. A. Lamberg and B. Kuhlback, "Effect of chlorothiazide and hydrochlorothiazide on the excretion of calcium in urine," Scandinavian Journal of Clinical and Laboratory Investigation , vol. 11, pp. 351-357, 1959. (hindawi.com)
  • Hydrochlorothiazide also decreases the excretion of calcium and uric acid, may increase the excretion of iodide, and may reduce glomerular filtration rate. (bioportfolio.com)
  • Hydrochlorothiazide is a diuretic and antihypertensive. (nih.gov)
  • For brands that may still be available, search under hydrochlorothiazide. (medbroadcast.com)
  • Hydrochlorothiazide is a diuretic/antihypertensive agent and triamterene is an antikaliuretic agent. (bioportfolio.com)
  • Drug Release Test 3 as published in the current USP monograph for Triamterene and Hydrochlorothiazide Capsules. (bioportfolio.com)
  • As with hydrochlorothiazide, triamterene may reduce glomerular filtration and renal plasma flow. (bioportfolio.com)
  • Grapefruit does not interact with hydrochlorothiazide. (livestrong.com)
  • To help you remember to take methyldopa and hydrochlorothiazide, take it around the same times every day. (medlineplus.gov)
  • Do not stop taking methyldopa and hydrochlorothiazide without talking to your doctor. (medlineplus.gov)
  • talk to your doctor about the risks and benefits of taking methyldopa and hydrochlorothiazide if you are 65 years of age or older. (medlineplus.gov)
  • Older adults should not usually take methyldopa and hydrochlorothiazide because it is not as safe as other medications that can be used to treat the same condition. (medlineplus.gov)
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking methyldopa and hydrochlorothiazide. (medlineplus.gov)
  • ask your doctor about the safe use of alcohol while you are taking methyldopa and hydrochlorothiazide. (medlineplus.gov)
  • Alcohol can make the side effects from methyldopa and hydrochlorothiazide worse. (medlineplus.gov)
  • A 57-year-old black man, known to be hypertensive, had been treated the previous year with hydrochlorothiazide and methyldopa with satisfactory control of his blood pressure. (annals.org)
  • Avoid drinking alcohol while you are taking hydrochlorothiazide because this may aggravate some of the side effects such as dizziness and dehydration. (bingj.com)
  • What is the most important information I should know about hydrochlorothiazide and aliskiren? (rexhealth.com)
  • What should I discuss with my healthcare provider before taking hydrochlorothiazide and aliskiren? (rexhealth.com)
  • Hydrochlorothiazide and aliskiren can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. (rexhealth.com)
  • It is not known whether hydrochlorothiazide and aliskiren passes into breast milk or if it could harm a nursing baby. (rexhealth.com)
  • Hydrochlorothiazide and aliskiren is not approved for use by anyone younger than 18 years old. (rexhealth.com)
  • You may have very low blood pressure while taking hydrochlorothiazide and aliskiren. (rexhealth.com)
  • If you need surgery or medical tests, tell the surgeon ahead of time that you are using hydrochlorothiazide and aliskiren. (rexhealth.com)
  • Hydrochlorothiazide affects the distal renal tubular mechanism of electrolyte reabsorption. (nih.gov)
  • El riesgo es mayor en personas con nivel de azúcar alto en la sangre (diabetes), enfermedad renal, enfermedad muy grave y/o en adultos mayores. (mskcc.org)
  • The losartan/hydrochlorothiazide combination preparation is marketed by Merck under the trade name Hyzaar and by Xeno Pharmaceuticals under the name Anzaplus. (wikipedia.org)
  • Hydrochlorothiazide helps to lower blood pressure by eliminating unneeded water and salt from the body. (medlineplus.gov)
  • Captopril/ hydrochlorothiazide can cause low blood pressure, especially during the first few days of starting treatment. (healthline.com)
  • Hydrochlorothiazide does not usually affect normal blood pressure. (nih.gov)
  • people with normal blood pressure are not usually affected by hydrochlorothiazide. (bingj.com)
  • 20 mg) and low doses of three blood pressure medications, beta blocker atenolol (50 mg), ACE inhibitor ramipril (5 mg) and diuretic hydrochlorothiazide (12.5 mg). (wikipedia.org)
  • They all are identical unless in the instruction is indicated that it is a combination drug that contains Hydrochlorothiazide and other anti-hypertensive agent. (rxshop.md)
  • Those on the losartan-hydrochlorothiazide combination had an initial mean systolic reduction of 6 mm Hg, which increased to 14 mm Hg at week 8 and 16 mm Hg by the close of the treatment period. (thefreedictionary.com)
  • FDA pregnancy category C. It is not known whether hydrochlorothiazide and spironolactone will harm an unborn baby. (cardiosmart.org)
  • Hydrochlorothiazide crosses the placental but not the blood-brain barrier and is excreted in breast milk. (nih.gov)
  • Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. (cardiosmart.org)
  • Hydrochlorothiazide passes into breast milk and could cause harm to a nursing baby. (cardiosmart.org)
  • Hydrochlorothiazide, one of the active ingredients of Amizide, is a sulfur containing medicine. (news-medical.net)
  • Not only can hydrochlorothiazide affect medical conditions, but it can also interfere with medications as well. (wisegeek.com)
  • Talk to your doctor or pharmacist before taking any other medications at the same time as hydrochlorothiazide because some may not be suitable (including those bought over the counter). (bingj.com)
  • you should know that hydrochlorothiazide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. (medlineplus.gov)

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