Huperzia
Huperzine B protects rat pheochromocytoma cells against oxygen-glucose deprivation-induced injury. (1/10)
AIM: To test the ability of huperzine B (HupB) to alleviate injury from oxygen-glucose deprivation (OGD) in the rat pheochromocytoma line PC12 cells. METHODS: After OGD for 3 h and reoxygenation for 24 h, neuronal morphology was observed by phase-contrast microscopy; cell survival was quantified by the reduction of MTT; malondialdehyde (MDA) was determined by the thiobarbituric acid; superoxide dismutase (SOD) was assayed by a modification of the xanthine/xanthine oxidase; and lactate (LA) was measured according to Marbach and Weil. RESULTS: OGD for 3 h and reoxygenation for 24 h triggered death in nearly 70 % of cells, along with major changes in morphology and biochemistry including elevated level of MDA, SOD activity, and LA content. Cells pretreated with HupB 1-100 micromol/L for 2 h showed significantly improved survival and reduced biochemical and morphologic signs of toxicity. CONCLUSION: HupB protected PC12 cells against OGD-induced injury, most likely by alleviating disturbances of oxidative and energy metabolism. (+info)Effects of huperzine A on secretion of nerve growth factor in cultured rat cortical astrocytes and neurite outgrowth in rat PC12 cells. (2/10)
AIM: To study the effects of huperzine A (HupA) on neuritogenic activity and the expression of nerve growth factor (NGF). METHODS: After being treated with 10 micromol/L HupA, neurite outgrowth of PC12 cells was observed and counted under phase-contrast microscopy. Mitogenic activity was assayed by [3H]thymidine incorporation. Cell cytotoxicity was evaluated by lactate dehydrogenase (LDH) release. AChE activity, mRNA and protein expression were measured by the Ellman method, RT-PCR, and Western blot, respectively. NGF mRNA and protein levels were determined by RT-PCR and ELISA assays. RESULTS: Treatment of PC12 cells with 10 micromol/L HupA for 48 h markedly increased the number of neurite-bearing cells, but caused no significant alteration in cell viability or other signs of cytotoxicity. In addition to inhibiting AChE activity, 10 micromol/L HupA also increased the mRNA and protein levels of this enzyme. In addition, following 2 h exposure of the astrocytes to 10 micromol/L HupA, there was a significant up-regulation of mRNA for NGF and P75 low-affinity NGF receptor. The protein level of NGF was also increased after 24 h treatment with HupA. CONCLUSION: Our findings demonstrate for the first time that HupA has a direct or indirect neurotrophic activity, which might be beneficial in treatment of neurodegenerative disorders such as Alzheimer disease. (+info)The mechanical diversity of stomata and its significance in gas-exchange control. (3/10)
Given that stomatal movement is ultimately a mechanical process and that stomata are morphologically and mechanically diverse, we explored the influence of stomatal mechanical diversity on leaf gas exchange and considered some of the constraints. Mechanical measurements were conducted on the guard cells of four different species exhibiting different stomatal morphologies, including three variants on the classical "kidney" form and one "dumb-bell" type; this information, together with gas-exchange measurements, was used to model and compare their respective operational characteristics. Based on evidence from scanning electron microscope images of cryo-sectioned leaves that were sampled under full sun and high humidity and from pressure probe measurements of the stomatal aperture versus guard cell turgor relationship at maximum and zero epidermal turgor, it was concluded that maximum stomatal apertures (and maximum leaf diffusive conductance) could not be obtained in at least one of the species (the grass Triticum aestivum) without a substantial reduction in subsidiary cell osmotic (and hence turgor) pressure during stomatal opening to overcome the large mechanical advantage of subsidiary cells. A mechanism for this is proposed, with a corollary being greatly accelerated stomatal opening and closure. Gas-exchange measurements on T. aestivum revealed the capability of very rapid stomatal movements, which may be explained by the unique morphology and mechanics of its dumb-bell-shaped stomata coupled with "see-sawing" of osmotic and turgor pressure between guard and subsidiary cells during stomatal opening or closure. Such properties might underlie the success of grasses. (+info)Crystallization and preliminary crystallographic analysis of an acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata. (4/10)
Polyketide synthase 1 (PKS1) from Huperzia serrata is a plant-specific type III polyketide synthase that shows an unusually versatile catalytic potential, producing various aromatic tetraketides, including chalcones, benzophenones, phlorogulucinols and acridones. Recombinant H. serrata PKS1 expressed in Escherichia coli was crystallized using the hanging-drop vapour-diffusion method. The crystals belonged to space group I222 or I2(1)2(1)2(1), with unit-cell parameters a = 73.3, b = 85.0, c = 137.7 A, alpha = beta = gamma = 90.0 degrees. Diffraction data were collected to 2.0 A resolution using synchrotron radiation at BL24XU of SPring-8. (+info)Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulation. (5/10)
(+info)Synthesis of (+/-)-7-hydroxylycopodine. (6/10)
(+info)Biotransformation of ursolic acid by an endophytic fungus from medicinal plant Huperzia serrata. (7/10)
Endophytic fungi were used not only for their producing bioactive products but also for their ability to transform natural compounds. An endophytic fungus, isolated from medicinal plant Huperzia serrata, was identified as Umbelopsis isabellina based on the internal transcribed spacer of ribosomal DNA (rDNA-ITS) region. It was used to transform ursolic acid (1), a pentacyclic triterpene. Incubation of ursolic acid with U. isabellina afforded three products, 3beta-hydroxy-urs-11-en-28,13-lactone (2), 3beta,7beta-dihydroxy-urs-11-en-28,13-lactone (3), 1beta,3beta-dihydroxy-urs-11-en-28,13-lactone (4). Although product 2 was a known compound, it was first obtained by microbial transformation. Products 3 and 4 were new compounds. The structural elucidation of the three compounds was achieved mainly by the 1D- and 2D-NMR, MS, IR data. The endophytic fungus U. isabellina can hydroxyate the C12-C13 double bond at position 13 of ursolic acid 1 and form a five-member lactone effectively. In the meantime, this fungus can also introduce the hydroxyl group at C-1 or C-7 of ursolic acid 1. (+info)Validation of a microscale extraction and high-throughput UHPLC-QTOF-MS analysis method for huperzine A in Huperzia. (8/10)
(+info)Huperzia is actually not a medical term itself, but it refers to a genus of clubmosses (Huperzia serrata) that are found in Asia. This plant contains a compound called huperzine A, which has been studied for its potential cognitive-enhancing and neuroprotective effects.
Huperzine A is an acetylcholinesterase inhibitor, which means it can increase the levels of the neurotransmitter acetylcholine in the brain by blocking the enzyme that breaks it down. This has led to its investigation as a possible treatment for Alzheimer's disease and other neurological disorders characterized by cognitive decline.
While Huperzia itself is not a medical term, huperzine A has been studied in clinical trials and is available as a dietary supplement in some countries. However, it is important to note that the use of huperzine A as a treatment for any medical condition should be done under the supervision of a healthcare provider, as it can have side effects and interact with other medications.
Alkaloids are a type of naturally occurring organic compounds that contain mostly basic nitrogen atoms. They are often found in plants, and are known for their complex ring structures and diverse pharmacological activities. Many alkaloids have been used in medicine for their analgesic, anti-inflammatory, and therapeutic properties. Examples of alkaloids include morphine, quinine, nicotine, and caffeine.
Huperzia
Huperzia appressa
Huperzia serrata
Huperzia lucidula
Huperzia australiana
Huperzia selago
Huperzia porophila
Phlegmariurus cumingii
Phlegmariurus llanganatensis
Phlegmariurus talpiphilus
Phlegmariurus espinosanus
Phlegmariurus columnaris
Phlegmariurus scabridus
Phlegmariurus mannii
Phlegmariurus dentatus
Phlegmariurus loxensis
Phlegmariurus austroecuadoricus
Phlegmariurus ascendens
Phlegmariurus compactus
Phlegmariurus hastatus
Phlegmariurus polydactylus
Phlegmariurus crassus
Phlegmariurus
List of Australian plant species described by Robert Brown
Huperzioideae
List of lycophytes of South Africa
Phlegmariurus nutans
Flora of Svalbard
Lycopodiopsida
Botany of Lord Auckland's Group and Campbell's Island
Huperzia - Wikipedia
Huperzia occidentalis in Flora of North America @ efloras.org
Huperzia lucidula; Shining Club-moss
Maryland Biodiversity - Checklist - Genus: Huperzia
EcoFlora - Huperzia
Huperzia serrata - NutraWiki
Huperzia Squarrosa | Live and Replica Planting
NEON Biorepository Data Portal - Huperzia appressa
Huperzia selago (northern firmoss): Go Botany
Huperzine A - Huperzia Serrata Extract - Chemical Warfare
Photo: Huperzia selago 0. | Henriette's Herbal Homepage
Flora of Mozambique: Species information: Huperzia phlegmaria
skandi 6 (=Huperzia selago)
Huperzia Serrata Extract gaosi oloa ma Tuuina | Agalelei
Digital Atlas of the Virginia Flora | Huperzia porophila × lucidula
Huperzine A: Remarkable Memory Nutrient - Huperzine A (Huperzia Serrata) - Limitless Mindset
Huperzia appressa - 16 images at image, phylogeny, nomenclature for Huperzia appressa
Digital Atlas of the Virginia Flora | Huperzia appressa (Desv.) A.& D. Love
Buy Huperzia Serrata 1% (Huperzine A) Powder Online in the UK | Customized Bends
Nootropic Ingredient Products - ECPlaza
Lady Bird Johnson Wildflower Center - The University of Texas at Austin
Blogger BioBlitz - Day Two - Purdon Bog & Baird Woods Photo Gallery by Bev Wigney at pbase.com
Australian Tropical Herbarium - Dr. Ashley Field - JCU Australia
Endangered Plants of North Carolina
Palaeos Plants: Taxon List
Ferns and Lycophytes of Minnesota - University of Minnesota Press
Mind Lab Pro Alternative: What's The Best One?
Selago6
- The type species is Lycopodium selago which became Huperzia selago. (wikipedia.org)
- Because of the subtle differences among the basic species and their propensity to form vegetatively reproducing hybrids, most Huperzia species and hybrids (except H . lucidula ) have been confused with H . selago , populations of which are confined to northeastern North America. (asu.edu)
- Huperzia selago subsp. (neonscience.org)
- Huperzia selago var. (neonscience.org)
- Photo: Huperzia selago 0. (henriettes-herb.com)
- Huperzia selago (L.) Bernh. (henriettes-herb.com)
Serrata Extract1
- Huperzine A (Huperzia serrata) extract 1%,99% Huperzine A is an active component of alkaloids obtained from huperzia serrata, a plant unique to China, and might not find elsewhere in the rest of the world. (ecplaza.net)
Lucidula4
- Huperzia jejuensis B.Y.Sun & J.Lim Huperzia kangdingensis (Ching) Ching Huperzia kunmingensis Ching Huperzia laipoensis Ching Huperzia lajouensis Ching Huperzia leishanensis X.Y.Wang Huperzia liangshanica (H.S.Kung) Ching & H.S.Kung Huperzia lucidula (Michx. (wikipedia.org)
- Huperzia occidentalis is similar to the eastern H . lucidula and occupies similar habitats. (efloras.org)
- The photographer's identification Huperzia lucidula has not been reviewed. (berkeley.edu)
- See also map for Huperzia appressa × lucidula. (vaplantatlas.org)
Extract1
- Soy ( Glycine max ) seed extracts (phosphatidylserine & glycerophosphorylcholine), Bacopa monnieri aerial parts extract, Huperzia serrata herb extract. (4life.com)
Lycopodium1
- Bernhardi separated Huperzia from Lycopodium. (wikipedia.org)
Clubmoss2
- Huperzia serrata (toothed clubmoss) is a plant known as a firmoss which contains the acetylcholinesterase inhibitor huperzine A. It is widely distributed over-the-counter as a nootropic and dietary supplement. (ecplaza.net)
- Huperzia Serrata is a type of clubmoss that contains a compound called Huperzine A. This has been found to support healthy levels of the 'messenger chemical' Acetylcholine for transporting messages around the brain. (onnit.com)
Appalachiana2
- Huperzia acicularis Björk, provisionally accepted Huperzia appalachiana Beitel & Mickel Huperzia archboldiana (Nessel) Holub Huperzia arunachalensis (D.D.Pant & P.S.Pandey) Fraser-Jenk. (wikipedia.org)
- The species was first distinguished at the species level by Beitel & Mickel in Amer. Fern J. 82(2):41-46 (1992) as Huperzia appalachiana. (vaplantatlas.org)
Firmoss1
- This alkaloid is a natural botanical nootropic that occurs in the firmoss huperzia serrata plant of Asia, which has been used for centuries in China as a memory enhancer. (limitlessmindset.com)
Appressa1
- Huperzia appressa is primarily a species of northern North America. (vaplantatlas.org)
Porophila1
- Huperzia minima (Herter) Holub Huperzia miyoshiana (Makino) Ching Huperzia muscicola W.M.Chu Huperzia nanchuanensis (Ching & H.S.Kung) Ching & H.S.Kung Huperzia nanlingensis Shrestha, F.W.Xing, X.P.Qi, Y.H.Yan & X.C.Zhang Huperzia occidentalis (Clute) Kartesz & Gandhi Huperzia porophila (F.E.Lloyd & Underw. (wikipedia.org)
Club moss3
- Huperzine A is a substance extracted from a plant called Chinese club moss (Huperzia serrata) . (chemical-warfare.com)
- Huperzine A is a natural compound extracted from the Chinese club moss Huperzia serrata. (picknsave.com)
- Huperzine A [(-)-HupA], an alkaloid isolated from the club moss, Huperzia serrata, is one such inhibitor, but the search for more potent and selective drugs continues. (proteopedia.org)
Flora of Nort2
- The Flora of North America distinguishes Huperzia from the epiphytic tropical genus Phlegmariurus on the basis of differences such as the former's complex and specialized shoots, the gemmae and the branchlets on which they are borne, and the unbranched gametophytes. (wikipedia.org)
- Earlier, the Flora of North America had also separated Huperzia from Phegmariurus. (wikipedia.org)
Huperzine3
- The primary benefit of Huperzia Serrataand Huperzine A is that it helps to improve memory capacity and access to stored memories. (nutrawiki.org)
- Huperzia Serrata 1% (Huperzine A) has a recommend daily intake of 0. (customizedblends.com)
- Huperzine A is extracted from Huperzia. (ecplaza.net)
Occidentalis1
- 5. Huperzia occidentalis (Clute) Kartesz & Gandhi, Phytologia. (efloras.org)
Rothm2
- Holub Huperzia catharinae (Christ) Holub Huperzia ceylanica (Spring) Rothm. (wikipedia.org)
- Huperzia phlegmaria (L.) Rothm. (mozambiqueflora.com)
Species5
- Huperzia is left with about 25 species, although not all have been formally transferred to other genera. (wikipedia.org)
- Other sources recognize only Huperzia, which then has about 340 species. (wikipedia.org)
- Their preferred hypothesis for the relationships of the three genera was: The majority of the species formerly placed in a broadly defined Huperzia belong in Phlegmariurus. (wikipedia.org)
- The PPG I classification stated there were 25 species in the genus Huperzia. (wikipedia.org)
- Hybrids between species of North American Huperzia are extremely common. (asu.edu)
Beitel1
- Huperzia chinensis (Christ) Ching Huperzia chishuiensis X.Y.Wang & P.S.Wang Huperzia continentalis Testo, A.Haines & A.V.Gilman Huperzia crispata (Ching) Ching Huperzia delavayi (Christ & Herter) Ching Huperzia emeiensis (Ching & H.S.Kung) Ching & H.S.Kung Huperzia erosa Beitel & W.H.Wagner Huperzia erubescens (Brack. (wikipedia.org)
Genus3
- The genus Huperzia was created by Johann Jakob Bernhardi in 1801. (wikipedia.org)
- The authors preferred the three-genus division, recognizing Huperzia, Phlegmariurus and Phylloglossum. (wikipedia.org)
- We distinguish the temperate and arctic Huperzia as a distinct genus because of its many differences from the tropical epiphytes, in particular the remarkably complex and specialized shoots, gemmiferous branchlets and gemmae, and the unbranched gametophytes. (asu.edu)
Alzheimer's1
- Huperzia serrata is used for Alzheimer's disease and general memory disorders. (nutrawiki.org)
Acetylcholine1
- As with other Acetylcholine supplements, using Huperzia may also lead to an improved learning capacity. (nutrawiki.org)
Chinese1
- Huperzia serrata, also referred to Chinese. (ecplaza.net)
Family2
- In the Pteridophyte Phylogeny Group classification of 2016 (PPG I), Huperzia is one of three genera in the subfamily Huperzioideae of the family Lycopodiaceae. (wikipedia.org)
- In the Pteridophyte Phylogeny Group classification of 2016 (PPG I), Huperzia is placed in the subfamily Huperzioideae of the family Lycopodiaceae. (wikipedia.org)
Extract6
- We are an enterprise that export Hplc huperzia serreta extract in ukraine to China, we are approved by the relevant state registratio. (comextbiotech.com)
- Primary Hplc huperzia serreta extract in ukraine and sell to different regions in China, product out there upon request. (comextbiotech.com)
- 50mg), L-Theanine (50mg), Huperzia Serrata Extract (std. (allstarhealth.com)
- 50% A-GPC) (60 mg), Huperzia serrata extract (std. (swansonvitamins.com)
- For example, Youthful Brain contains an extract from the plant Huperzia Serrata, which has been shown to improve memory and cognitive function. (naspcenter.org)
- They include Cat's Claw Extract, Bacopa, Oat Straw, Huperzia Serrata, and our Focus and Flow Blends to help you realize limitless potential. (maineinns.com)
Firmoss huperzia serrata2
- This alkaloid is a natural botanical nootropic that occurs in the firmoss huperzia serrata plant of Asia, which has been used for centuries in China as a memory enhancer. (limitlessmindset.com)
- Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata. (adooq.com)
Haleakalae4
- Holub Huperzia haleakalae (Brack. (wikipedia.org)
- Kaliwatan sa tanom ang Huperzia haleakalae . (wikipedia.org)
- [2] Ang Huperzia haleakalae sakop sa kahenera nga Huperzia , ug kabanay nga Lycopodiaceae . (wikipedia.org)
- These plots show the elevations and times of year where the plant Huperzia haleakalae has been observed. (wildflowersearch.org)
Club Moss2
- Huperzine-A is a powerful nootropic derived from the Chinese Club Moss plant, Huperzia serrata. (human-nature.com)
- Huperzine A (HupA), an alkaloid found in the club moss Huperzia serrata , has been used for centuries in Chinese folk medicine to treat dementia. (nih.gov)
Lycopodiaceae2
- In the Pteridophyte Phylogeny Group classification of 2016 (PPG I), Huperzia is one of three genera in the subfamily Huperzioideae of the family Lycopodiaceae. (wikipedia.org)
- In the Pteridophyte Phylogeny Group classification of 2016 (PPG I), Huperzia is placed in the subfamily Huperzioideae of the family Lycopodiaceae. (wikipedia.org)
Holub10
- Huperzia acicularis Björk, provisionally accepted Huperzia appalachiana Beitel & Mickel Huperzia archboldiana (Nessel) Holub Huperzia arunachalensis (D.D.Pant & P.S.Pandey) Fraser-Jenk. (wikipedia.org)
- Huperzia asiatica (Ching) N.Shrestha & X.C.Zhang Huperzia australiana (Herter) Holub Huperzia beccarii (Alderw. (wikipedia.org)
- Holub Huperzia beiteliana Mickel Huperzia bucahwangensis Ching Huperzia campestris (Alderw. (wikipedia.org)
- Holub Huperzia catharinae (Christ) Holub Huperzia ceylanica (Spring) Rothm. (wikipedia.org)
- Holub Huperzia europaea Björk, provisionally accepted Huperzia everettii (Herter) Holub Huperzia fuegiana (Roiv. (wikipedia.org)
- Holub Huperzia gedeana (Alderw. (wikipedia.org)
- Holub Huperzia goliathensis (Alderw. (wikipedia.org)
- Holub Huperzia herteriana (Kümmerle) T.Sen & U.Sen Huperzia javanica (Sw. (wikipedia.org)
- Huperzia minima (Herter) Holub Huperzia miyoshiana (Makino) Ching Huperzia muscicola W.M.Chu Huperzia nanchuanensis (Ching & H.S.Kung) Ching & H.S.Kung Huperzia nanlingensis Shrestha, F.W.Xing, X.P.Qi, Y.H.Yan & X.C.Zhang Huperzia occidentalis (Clute) Kartesz & Gandhi Huperzia porophila (F.E.Lloyd & Underw. (wikipedia.org)
- Huperzia apolinari-mariae (Nessel) Holub in Folia Geobot. (kew.org)
Bernh1
- Huperzia Bernh. (fernsoftheworld.com)
Trevis1
- Huperzia miniata (Spring) Trevis. (wikipedia.org)
Brack1
- Huperzia chinensis (Christ) Ching Huperzia chishuiensis X.Y.Wang & P.S.Wang Huperzia continentalis Testo, A.Haines & A.V.Gilman Huperzia crispata (Ching) Ching Huperzia delavayi (Christ & Herter) Ching Huperzia emeiensis (Ching & H.S.Kung) Ching & H.S.Kung Huperzia erosa Beitel & W.H.Wagner Huperzia erubescens (Brack. (wikipedia.org)
Bacopa1
- It contains a blend of natural ingredients, including Bacopa Monnieri, Huperzia Serrata, and Alpha-GPC. (bcr.org)
Huperzine3
- Of the alkaloids isolated from Huperzia serrata, huperzine A has been extensively studied for pharmacological and clinical effects in relation to treatment of cognitive disorders. (medicinalplants.us)
- Huperzine B, also from Huperzia serrata, attenuates H2O2-and oxygen-glucose-deprivation-induced injury in the rat pheochromocytoma cell line PC 12, indicating that it has a neuroprotective action. (medicinalplants.us)
- Huperzine-A vs Huperzia serrata What are the Differences? (human-nature.com)
Endophytic2
- 16. Isolation, diversity and acetylcholinesterase inhibitory activity of the culturable endophytic fungi harboured in Huperzia serrata from Jinggang Mountain, China. (nih.gov)
- New insights into the composition and diversity of endophytic bacteria in cultivated Huperzia serrata . (bvsalud.org)
Ching1
- Huperzia medogensis Ching & Y.X.Lin Huperzia meghalaica Fraser-Jenk. (wikipedia.org)