Any arthropod of the subclass ACARI except the TICKS. They are minute animals related to the spiders, usually having transparent or semitransparent bodies. They may be parasitic on humans and domestic animals, producing various irritations of the skin (MITE INFESTATIONS). Many mite species are important to human and veterinary medicine as both parasite and vector. Mites also infest plants.
Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They are proteins, found in mite feces or mite extracts, that can cause ASTHMA and other allergic diseases such as perennial rhinitis (RHINITIS, ALLERGIC, PERENNIAL) and atopic dermatitis (DERMATITIS, ATOPIC). More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the above two species, are among the strongest mite immunogens in humans.
Rhinitis, Allergic, Perennial
Bedding and Linens
Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
Rhinitis, Allergic, Seasonal
Air Pollutants, Occupational
Interior Design and Furnishings
Nasal Provocation Tests
Bronchial Provocation Tests
Polycyclic Hydrocarbons, Aromatic
A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)
A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.
A polysymptomatic condition believed by clinical ecologists to result from immune dysregulation induced by common foods, allergens, and chemicals, resulting in various physical and mental disorders. The medical community has remained largely skeptical of the existence of this "disease", given the plethora of symptoms attributed to environmental illness, the lack of reproducible laboratory abnormalities, and the use of unproven therapies to treat the condition. (From Segen, Dictionary of Modern Medicine, 1992)
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)
Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.
Halogenated Diphenyl Ethers
Exposure of the female parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring. It includes pre-conception maternal exposure.
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
Bronchoalveolar Lavage Fluid
A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)
A diffuse parenchymal lung disease caused by inhalation of dust and by tissue reaction to their presence. These inorganic, organic, particulate, or vaporized matters usually are inhaled by workers in their occupational environment, leading to the various forms (ASBESTOSIS; BYSSINOSIS; and others). Similar air pollution can also have deleterious effects on the general population.
Genetic Predisposition to Disease
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
United States Environmental Protection Agency
2S Albumins, Plant
Prenatal Exposure Delayed Effects
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Enzyme-Linked Immunosorbent Assay
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
The science, art, or technology dealing with processes involved in the separation of metals from their ores, the technique of making or compounding the alloys, the techniques of working or heat-treating metals, and the mining of metals. It includes industrial metallurgy as well as metallurgical techniques employed in the preparation and working of metals used in dentistry, with special reference to orthodontic and prosthodontic appliances. (From Jablonski, Dictionary of Dentistry, 1992, p494)
Great Lakes Region
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Peak Expiratory Flow Rate
Animals which have become adapted through breeding in captivity to a life intimately associated with humans. They include animals domesticated by humans to live and breed in a tame condition on farms or ranches for economic reasons, including LIVESTOCK (specifically CATTLE; SHEEP; HORSES; etc.), POULTRY; and those raised or kept for pleasure and companionship, e.g., PETS; or specifically DOGS; CATS; etc.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
Sick Building Syndrome
A group of symptoms that are two- to three-fold more common in those who work in large, energy-efficient buildings, associated with an increased frequency of headaches, lethargy, and dry skin. Clinical manifestations include hypersensitivity pneumonitis (ALVEOLITIS, EXTRINSIC ALLERGIC); allergic rhinitis (RHINITIS, ALLERGIC, PERENNIAL); ASTHMA; infections, skin eruptions, and mucous membrane irritation syndromes. Current usage tends to be less restrictive with regard to the type of building and delineation of complaints. (From Segen, Dictionary of Modern Medicine, 1992)
Nasal Lavage Fluid
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Forced Expiratory Volume
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
Carbon-containing phosphoric acid derivatives. Included under this heading are compounds that have CARBON atoms bound to one or more OXYGEN atoms of the P(=O)(O)3 structure. Note that several specific classes of endogenous phosphorus-containing compounds such as NUCLEOTIDES; PHOSPHOLIPIDS; and PHOSPHOPROTEINS are listed elsewhere.
Multiple Chemical Sensitivity
An acquired disorder characterized by recurrent symptoms, referable to multiple organ systems, occurring in response to demonstrable exposure to many chemically unrelated compounds at doses below those established in the general population to cause harmful effects. (Cullen MR. The worker with multiple chemical sensitivities: an overview. Occup Med 1987;2(4):655-61)
Disease Models, Animal
The maintenance of certain aspects of the environment within a defined space to facilitate the function of that space; aspects controlled include air temperature and motion, radiant heat level, moisture, and concentration of pollutants such as dust, microorganisms, and gases. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Nitrogen oxide (NO2). A highly poisonous gas. Exposure produces inflammation of lungs that may only cause slight pain or pass unnoticed, but resulting edema several days later may cause death. (From Merck, 11th ed) It is a major atmospheric pollutant that is able to absorb UV light that does not reach the earth's surface.
Dermatitis, Allergic Contact
Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).
Agricultural Workers' Diseases
Diseases in persons engaged in cultivating and tilling soil, growing plants, harvesting crops, raising livestock, or otherwise engaged in husbandry and farming. The diseases are not restricted to farmers in the sense of those who perform conventional farm chores: the heading applies also to those engaged in the individual activities named above, as in those only gathering harvest or in those only dusting crops.
Allergic reaction to products containing processed natural rubber latex such as rubber gloves, condoms, catheters, dental dams, balloons, and sporting equipment. Both T-cell mediated (HYPERSENSITIVITY, DELAYED) and IgE antibody-mediated (HYPERSENSITIVITY, IMMEDIATE) allergic responses are possible. Delayed hypersensitivity results from exposure to antioxidants present in the rubber; immediate hypersensitivity results from exposure to a latex protein.
Hypoallergenic dog breed
"Quantitation of house dust mites and house dust mite allergens in the microenvironment of dogs". American Journal of Veterinary ... "Environmental Exposure to Allergens of Different Dog Breeds and Relevance in Allergological Diagnostics". Journal of Toxicology ... February 2003). "Current mite, cat, and dog allergen exposure, pet ownership, and sensitization to inhalant allergens in adults ... Salo PM, Arbes SJ, Crockett PW, Thorne PS, Cohn RD, Zeldin DC (March 2008). "Exposure to multiple indoor allergens in US homes ...
... and house dust mite extract on bronchial epithelial cells, where FAM83A expression also increases after exposure. FAM83A shows ... With increased expression to irritants and allergens along with an indirect relationship with ATF2, it suggests FAM83A may be ... Microarray expression data also show different environmental conditions, especially irritants. Such irritants can be cigarette ... Vroling AB, Duinsbergen D, Fokkens WJ, van Drunen CM (November 2007). "Allergen induced gene expression of airway epithelial ...
Microbiomes of the built environment
"House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus ... Examples of types of built environment data covered in this review include building characteristics and environmental ... Studies of dust in various homes has shown that the microbiome found in the dust is correlated to the risk of children in those ... Factors that are thought to be important include humidity, pH, chemical exposures, temperature, filtration, surface materials, ...
House dust mite
"Environmental assessment and exposure control of dust mites: a practice parameter". Annals of Allergy, Asthma & Immunology. 111 ... "House dust mite allergen in US beds: Results from the first national survey of lead and allergens in housing". Journal of ... House dust mites (HDM, or simply dust mites) are mites found in association with dust in dwellings. They are known for ... The average life cycle for a house dust mite is 65-100 days. A mated female house dust mite can live up to 70 days, laying ...
氣喘 - 維基百科，自由的百科全書
普遍認為氣喘是因為基因和環境因素（英語：environmental factors）共同導致的。環境因素通常包含：暴露於空氣汙染和過敏原（allergen） 。 其他可能的誘發因子包含阿司匹林和β受體阻斷藥之類的藥物。 對氣喘的診斷通常 ... House dust mite control measures for asthma. Cochrane Database Syst Rev. 2008, (2): CD001187. PMID 18425868. doi:10.1002/ ... Does exposure to indoor allergens contribute to the development of asthma and allergy
Asma bahasa Indonesia, ensiklopedia bebas
"House dust mite control measures for asthma". Cochrane Database Syst Rev (2): CD001187. PMID 18425868. doi:10.1002/14651858. ... Arshad, SH (2010 Jan). "Does exposure to indoor allergens contribute to the development of asthma and allergy?". Current ... Environmental health perspectives 118 (3): 313-7. PMID 20064771. Cite uses deprecated parameter ,coauthors=. (bantuan) ... "The role of allergen exposure and avoidance in asthma". Adolesc Med State Art Rev 21 (1): 57-71, viii-ix. PMC 2975603. PMID ...
Pumu, kamusi elezo huru
61.0 61.1 61.2 61.3 Baxi SN, Phipatanakul W (April 2010). "The role of allergen exposure and avoidance in asthma". Adolesc Med ... "House dust mite control measures for asthma". Cochrane Database Syst Rev (2): CD001187. doi:10.1002/14651858.CD001187.pub3 . ... Miller, RL; Ho SM (March 2008). "Environmental epigenetics and asthma: current concepts and call for studies". American Journal ... Arshad, SH (2010 Jan). "Does exposure to indoor allergens contribute to the development of asthma and allergy?". Current ...
The role of allergen exposure and avoidance in asthma". Adolesc Med State Art Rev. 21 (1): 57-71, viii-ix. PMC 2975603 . PMID ... House dust mite control measures for asthma". Cochrane Database Syst Rev (2): CD001187. doi:10.1002/14651858.CD001187.pub3. ... McGwin, G (2010 Mar). „Formaldehyde exposure and asthma in children: a systematic review". Environmental health perspectives. ... Arshad, SH (2010 Jan). „Does exposure to indoor allergens contribute to the development of asthma and allergy?". Current ...
House dust mite
"Environmental assessment and exposure control of dust mites: a practice parameter". Annals of Allergy, Asthma & Immunology. 111 ... "House dust mite allergen in US beds: Results from the first national survey of lead and allergens in housing". Journal of ... Mayne's house dust mite) The dust mites are cosmopolitan members of the mite family Pyroglyphidae. House dust mites, due to ... A typical house dust mite measures 0.2-0.3 mm in length. The body of the house dust mite has a striated cuticle. They feed on ...
... is associated with exposure to indoor allergens. Common indoor allergens include dust mites, cockroaches, animal dander ... Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as ... Gøtzsche, Peter C; Johansen, Helle Krogh (2008). "House dust mite control measures for asthma". Cochrane Database of Systematic ... Many environmental factors have been associated with asthma's development and exacerbation, including, allergens, air pollution ...
... indoor environmental quality of Eco-houses has also improved health and satisfaction among occupants by reducing exposure to ... via the dust collection bag and filter) to the outside, thus no microscopic particles of dust remain in the house. Load bearing ... pollutants, allergens, and other contaminants. According to Dr. Joseph Allen and his research at Harvard T.H. Chan School of ... An eco-house starts life facing the Sun. Ideally, the site for the house should have a south westerly aspect and be protected ...
... is typically triggered by environmental allergens such as pollen, pet hair, dust, or mold. Inherited ... house dust mites), thereby inducing specific long-term tolerance. Allergy immunotherapy can be administered orally (as ... Exposure to animals early in life. Medication. Nasal steroids, antihistamines such as diphenhydramine, cromolyn sodium, ... Exposing people to larger and larger amounts of allergen, known as allergen immunotherapy, is often effective. The allergen ...
a b c d Baxi SN, Phipatanakul W (1 aprilie 2010). „The role of allergen exposure and avoidance in asthma". Adolesc Med State ... House dust mite control measures for asthma". Cochrane Database Syst Rev (2): CD001187. doi:10.1002/14651858.CD001187.pub3. ... McGwin, G (1 martie 2010). „Formaldehyde exposure and asthma in children: a systematic review.". Environmental health ... Arshad, SH (1 ianuarie 2010). „Does exposure to indoor allergens contribute to the development of asthma and allergy?". Current ...
"House dust mite control measures for asthma". Cochrane Database Syst Rev (2): CD001187. PMID 18425868. doi:10.1002/14651858. ... Arshad, SH (2010). "Does exposure to indoor allergens contribute to the development of asthma and allergy?". Current allergy ... McGwin, G; Lienert, J; Kennedy, JI (2010). "Formaldehyde exposure and asthma in children: a systematic review.". Environmental ... Liu AH (2004). "Something old, something new: indoor endotoxin, allergens and asthma". Paediatr Respir Rev 5 (Suppl A): S65-71 ...
... is typically triggered by environmental allergens such as pollen, pet hair, dust, or mold. Inherited genetics ... house dust mites), thereby inducing specific long-term tolerance. Allergen immunotherapy is the only treatment that alters the ... Symptom onset is often within minutes following allergen exposure and can affect sleep, and the ability to work or study. Some ... Additionally, environmental exposures such as air pollution and maternal tobacco smoking can increase an individual's chances ...
They and their feces and other allergens they produce are major constituents of house dust, but because they are so heavy they ... The danger of coal dust resulted in environmental legislation regulating work place air quality in some jurisdictions. In ... A video on reducing dust exposure in the workplace. Dust control is the suppression of solid particles with diameters less than ... House dust can become airborne easily. Care is required when removing dust to avoid causing the dust to become airborne. A ...
Բրոնխիալ ասթմա - Վիքիպեդիա՝ ազատ հանրագիտարան
79,0 79,1 79,2 79,3 «The role of allergen exposure and avoidance in asthma»։ Adolesc Med State Art Rev 21 (1): 57-71, viii-ix։ ... Calderon Moises (2015)։ «Respiratory allergy caused by house dust mites: What do we really know?»։ Journal of Allergy and ... Rao D, Phipatanakul, W (October 2011)։ «Impact of environmental controls on childhood asthma.»։ Current allergy and asthma ... PC Gøtzsche, HK Johansen (2008)։ Gøtzsche Peter C, ed.։ «House dust mite control measures for asthma»։ Cochrane Database of ...
House dust mite reduction and avoidance measures have been studied in low quality trials and have not shown evidence of ... Allergic contact dermatitis occurs upon exposure to an allergen, causing a hypersensitivity reaction in the skin. Treatment of ... The cause of dermatitis is unknown but is presumed to be a combination of genetic and environmental factors. The hygiene ... Nankervis H, Pynn EV, Boyle RJ, Rushton L, Williams HC, Hewson DM, Platts-Mills T (January 2015). "House dust mite reduction ...
Sustained growth of house dust mites by A. penicillioides can also be a health hazard. House dust mites can activate mast cells ... The propagules may be introduced to grain through exposure to airborne dusts during harvesting, storage and processing. The ... It was shown that allergen profiles of larval mites without this fungus are similar to adult mites with the fungus. Fungus-free ... Environmental Microbiology 19.2 (2017):687-697. Samson, edited by Robert A.; Pitt, John I. (1990). Modern concepts in ...
Environmental health policy
... and improving poor housing conditions. The United States has several policies to deal with chemical exposure, air quality, ... Environmental factors such as, air pollutants, tobacco smoke, emission fumes, and other allergens in the air when absorbed ... The law requires property owners to remove any lead based paint and dust from the premise and obtain a certificate of occupancy ... attributed to more exposure to environmental risks and lack of access to health care. Diseases attributed to environmental ...
In adults, the prevalence of IgE sensitization to allergens from house dust mite and cat, but not grass, seem to decrease over ... However, upon re-exposure, the allergen binds to membrane-bound IgE which activates the mast cells, releasing a variety of ... Case Studies in Environmental Medicine (CSEM): Environmental Triggers of Asthma - Agency for Toxic Substances and Disease ... Allergens can be a number of different substances, for example pollen, dander, dust mites, foods. Atopic reactions are caused ...
It is the most common mould found in the floor dust in houses and is largely considered as an indoor mould.M. racemosus is ... "Allergen, Fungi and Molds, Mucor racemosus". Arup Laboratories. Bogar, B.; Szakacs, G.; Pandey, A.; Abdulhameed, S.; Linden, J. ... It possesses the ability to adapt phenotypically to several different antibiotics after exposure to a single drug, which makes ... Like many zygomycetes, M. racemosus reproduces both sexually and asexually depending on environmental conditions. During sexual ...
They and their feces and other allergens which they produce are major constituents of house dust, but because they are so heavy ... Medical geology Mineral dust Nephelometer Occupational dust exposure Sawdust "Dust". Merriam-Webster. Archived from the ... The danger of coal dust resulted in environmental legislation regulating work place air quality in some jurisdictions. In ... House dust can become airborne easily. Care is required when removing dust to avoid causing the dust to become airborne. A ...
Mold health issues
Shoemaker RC, House DE (2006). "Sick building syndrome (SBS) and exposure to water-damaged buildings: time series study, ... and environmental controls such as ventilation and suppression of dust. When mold cannot be prevented, the CDC recommends clean ... Bacteria, fungi, allergens, and particle-bound semi-volatile organic compounds (SVOCs) can all be found in bedding and pillows ... 2015-05-26). "Environmental mold and mycotoxin exposures elicit specific cytokine and chemokine responses". PLOS ONE. 10 (5): ...
Air Pollution Exposures and Children's Health. Vol. 89, Suppl. 1 May-June 1998. pg. S43-48 Zock, JP., Plana, E., Jarvis D. et ... VOCs tend to evaporate and then to be inhaled into the lungs or adsorbed by dust, which can also be inhaled. Aerosolized (spray ... They are a type of consumer goods, designed particularly to assist cleaning, house and yard maintenance, cooking, pest control ... 49-52 Burton, A. Environmental Health Perspectives - Indoor Air Quality. Vol. 115 #7 (2007) pg. 350 Raizenne M., Dales R., ...
It was also detected in house dust in Canada, USA and western Europe. The potential of fungi in indoor sources to cause asthma ... The health effect of chronic exposure to airborne fungi in indoor environment is known to be associated with both allergens and ... Conrad, A; Seiwert, M; Hünken, A; Quarcoo, D; Schlaud, M; Groneberg, D (January 2013). "The German Environmental Survey for ... It is also found in indoor air, house dust, and soil. One distinctive feature of W. sebi is its relationship with water ...
A study done in North Carolina on children's exposure showed that chlorpyrifos was detected in 50% of the food, dust, and air ... Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology, Continuation of ... showed that children who lived in closer proximity to farmlands had higher levels of chlorpyrifos residues from house dust. ... They were found to have a heightened immune responses to common allergens and increased antibiotic sensitivities, elevated CD26 ...
Asthma - Simple English Wikipedia, the free encyclopedia
Sullivan, John Burke; Krieger, Gary R. (2001). Clinical Environmental Health and Toxic Exposures. Lippincott Williams & Wilkins ... Most often the Asthma is triggered by allergens. One big source of allergens is the carpet. Totally replace it with a tiles ... They are also more sensitive to things things like chemicals, smoke and dust (environmental antigens). This hypersensitivity ... If a person goes from being outside in the cold into a warm house the sudden change can cause a broncospasm. Sudden changes in ...
Agricultural safety and health
Identify high dust hazards around the farmstead and reduce dust exposure by cleaning these areas. When cleaning a barn or ... Frequently remove animal waste from the barn to decrease ammonia build-up and reduce exposure to urine and faecal allergens. ... pesticide exposure, childhood asthma and environmental justice among Mexican-American farmworkers". Health & Place. 32: 83-92. ... Ventilate animal housing areas to decrease the accumulation of ammonia and other gases. ...
Environmental Health Center-Dallas, Texas. "Buying An Allergy-Friendly House: Q and A with Dr. Stephen Lockey". Allergy & ... There is recognition from the medical community relating to the benefits of floor heating especially as it relates to allergens ... viruses and dust mites. By removing the sensible heating load from the total HVAC (Heating, Ventilating, and Air Conditioning) ... and product mishandling such as exposure to ultraviolet radiation. Pre-pour pressure tests required by concrete installation ...
Exposure to bed bugs may trigger an asthma attack via the effects of airborne allergens although evidence of this association ... House dust mite (house dust mite allergy, oral mite anaphylaxis). Trombidiformes. *Demodex brevis / Demodex folliculorum ( ... Journal of Environmental Health. 70 (9): 24-7, 52-3. PMID 18517150. Archived from the original (PDF) on 26 April 2012.. ... Bed bugs occur around the world. Before the 1950s about 30% of houses in the United States had bedbugs. Rates of ...
"House dust mite control measures for asthma". Cochrane Database Syst Rev (2): CD001187. doi:10.1002/14651858.CD001187.pub3. ... McGwin, G (2010 Mar). "Formaldehyde exposure and asthma in children: a systematic review". Environmental health perspectives. ... Arshad, SH (2010 Jan). "Does exposure to indoor allergens contribute to the development of asthma and allergy?". Current ... "The role of allergen exposure and avoidance in asthma". Adolesc Med State Art Rev. 21 (1): 57-71, viii-ix. PMC 2975603 . PMID ...
Asthma - Simple English Wikipedia, the free encyclopedia
They are also more sensitive to things things like chemicals, smoke and dust (environmental antigens). This hypersensitivity ... Most often the Asthma is triggered by allergens. One big source of allergens is the carpet. Totally replace it with a tiles ... Sullivan, John Burke; Krieger, Gary R. (2001). Clinical Environmental Health and Toxic Exposures. Lippincott Williams & Wilkins ... If a person goes from being outside in the cold into a warm house the sudden change can cause a broncospasm. Sudden changes in ...
Exposure to hay can also trigger Allergic rhinitis for people who are hypersensitive to airborne allergens. ... is a hypersensitivity pneumonitis induced by the inhalation of biologic dusts coming from hay dust or mold spores or other ... Singleton, GR (1985). "A Demographic and Gentic Study of House Mice, Mus musulus, Colonizing Pasture Haystacks on a Cereal Farm ... or the plastic's environmental footprint. ... sprinkled with water or subjected to steaming to reduce dust. ...
New York: Random House. ISBN 0-375-50797-3.. *^ a b c Perfume connoisseurs speak of a fragrance's "sillage", or the discernible ... a b Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products  Archived 3 ... Many natural aromatics, such as oakmoss absolutes, basil oil, rose oil and many others contain allergens or ... This is due to the use of heat, harsh solvents, or through exposure to oxygen in the extraction process which will denature the ...
... such as the house dust mite, is there ingestion of solid food particles, and thus exposure to internal parasites, although ... A well-known effect of mites on humans is their role as an allergen and the stimulation of asthma in people affected by the ... "Selection of environmental temperature by the yellow scorpion Tityus serrulatus Lutz & Mello, 1922 (Scorpiones, Buthidae)" ( ...
The house dust mite, its feces and chitin are common allergens around the home ... Other countries, in view of the differences in the genetic profiles of their citizens and different levels of exposure to ... However, some individuals may respond to many common environmental antigens. This hereditary predisposition is called atopy. In ... Types of allergens. Allergens can be found in a variety of sources, such as dust mite excretion, pollen, pet dander, or ...
... increased exposure to perennial allergens due to housing changes and increasing time spent indoors, and changes in cleanliness ... Four major environmental candidates are alterations in exposure to infectious diseases during early childhood, environmental ... Many allergens such as dust or pollen are airborne particles. In these cases, symptoms arise in areas in contact with air, such ... If later exposure to the same allergen occurs, the allergen can bind to the IgE molecules held on the surface of the mast cells ...
Lead and lead compounds fact sheet National Survey of Lead and Allergens in Housing Annotated bibliography of works on paint ... High levels of exposure can be lethal. In Canada, regulations were first enacted under the Hazardous Products Act in 1976 that ... Environmental issues with paint Lead-based paint in the United Kingdom Lead-based paint in the United States Lead tetroxide ... It is dangerous to children because it tastes sweet, therefore encouraging children to put lead chips and toys with lead dust ...
The United States Environmental Protection Agency (EPA) allows no more than 0.016 ppm formaldehyde in the air in new buildings ... A proposed mechanism for the formation is the hydrogenation of CO ice: H + CO → HCO HCO + H → CH2O HCN, HNC, H2CO, and dust ... A 1988 Canadian study of houses with urea-formaldehyde foam insulation found that formaldehyde levels as low as 0.046 ppm were ... Mice studied over an exposure to a high dose of formaldehyde (3ppm), showed increased NO− 3 levels in plasma. This result ...
... the actual amounts vary among perfume houses. An EdT from one house may have a higher concentration of aromatic compounds than ... However, the presence of oxygen in the head space of the bottle and environmental factors will in the long run alter the smell ... This is due to the use of heat, harsh solvents, or through exposure to oxygen in the extraction process which will denature the ... The limits above which the allergens are required to be declared are 0.001% for products intended to remain on the skin, and ...
The plant is a major source of indoor allergens, ranking as the third-most common cause of indoor allergies after dust and pets ... the hidden allergen in the house". Hautarzt. 49 (1): 2-5. doi:10.1007/s001050050692. PMID 9522185. S2CID 29908249. "Ficus spp ... In extreme cases, Ficus sap exposure can cause anaphylactic shock in latex allergy sufferers. The consumption of parts of ... The plant is also sensitive to changes in environmental factors such as temperature, humidity and moving. Numerous cultivars ...
Pathophysiology of asthma
Allergens from nature, typically inhaled, which include waste from common household pests, the house dust mite and cockroach, ... During an asthma episode, inflamed airways react to environmental triggers such as smoke, dust, or pollen. The airways narrow ... They are thought to be primarily in response to the exposure of the airway epithelium to cold, dry air. Hormonal changes in ... The humoral immune system produces antibodies against the inhaled allergen. Later, when a patient inhales the same allergen, ...
One study found that semen exposure from a broken condom was about half that of unprotected intercourse; semen exposure from a ... Dry dusting powders are applied to latex condoms before packaging to prevent the condom from sticking to itself when rolled up ... An allergen-free condom made of synthetic latex (polyisoprene) is also available. The most common non-latex condoms are made ... The United States Environmental Protection Agency also has expressed concerns that many animals might mistake the litter for ...
Exposure to hay can also trigger allergic rhinitis for people who are hypersensitive to airborne allergens. Hay baled before it ... is a hypersensitivity pneumonitis induced by the inhalation of biologic dusts coming from hay dust or mold spores or other ... ISBN 978-0-87351-395-1. Singleton, GR (1985). "A Demographic and Gentic Study of House Mice, Mus musulus, Colonizing Pasture ... or the plastic's environmental footprint. After World War II, British farmers found that the demand outstripped supply for ...
House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus...
... by the impact of environmental exposures on the gastrointestinal microbiome composition and, by extension, its impact on the ... House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus ... House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus ... that exposure of mice to dog-associated house dust protects against ovalbumin or cockroach allergen-mediated airway pathology. ...
Evaluation of Efficacy and Safety of Specific Immunotherapy With Modified Allergen Extracts of House Dust Mites
Environmental exposure to food allergens may be a risk factor for cutaneous sensitization. Previous studies could detect peanut ... Studies with pollen allergen immunotherapy are limited to observational studie.... Sensitivity to House Dust Mites Allergens ... House dust mites (HDM) are major allergens that cause allergic rhinitis (AR). Allergen-specific subcutaneous immunotherapy ( ... Immunotherapy of House Dust Mite Allergy.. House dust mite (HDM) is a predominant source of indoor aeroallergen worldwide, ...
Tips From Other Journals - American Family Physician
Allergen avoidance is accomplished through environmental control aimed at reducing exposure to potential allergens. This may ... Important perennial allergens include house dust mites, indoor molds, animal dander and occupational allergens. ... Lee and Arriola discuss three therapies: (1) allergen avoidance, (2) pharmacologic treatment to prevent and control symptoms ... Other measures include enclosing mattresses or pillows with allergen-proof casings, and eliminating carpeting. When these ...
Federal Register :: Agency Information Collection Activities: Proposed Collection; Comment Request; National...
Indoor allergens include those from house dust mites, cockroaches, mold, and animal dander. In addition, exposure to ... In response, EPA launched efforts to better understand the role that environmental factors, including airborne allergens and ... will have taken steps to reduce their exposure to indoor environmental asthma triggers by 2005. ... Environmental Protection Agency Dates:. Comments must be submitted on or before April 30, 2005.. Comments Close:. 04/30/2005. ...
Development of asthmatic inflammation in mice following early-life exposure to ambient environmental particulates and chronic...
... using clinically relevant allergens such as house dust mite or cockroach allergen, have been reported (Kulhankova et al., 2009 ... 2003). Exposure to endotoxin and allergen in early life and its effect on allergen sensitization in mice. J. Allergy Clin. ... 2010). Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice. Respir. Res. 11, 14. ... Exposure of AEC to environmental particulates, but not to carbon black, was associated with significant upregulation of ...
Soot and house dust mite allergen cause eosinophilic laryngitis in an animal model. | Sigma-Aldrich
Further investigation into eosinophilic laryngitis as a distinct clinical entity caused by exposure to environmental allergen ... Soot and house dust mite allergen cause eosinophilic laryngitis in an animal model.. [Peter C Belafsky, Janice Peake, Suzette M ... To evaluate the association between iron soot, house dust mite allergen (HDMA), and CL in an established animal model. Twenty- ... four guinea pigs were separated into four 6-week exposure groups: 1) saline (allergen control) + filtered air (pollution ...
CDC - Asthma - Potentially Effective Interventions for Asthma - Mothers - Medical clinics/physicians' offices
The program included the following strategies: avoiding of house dust mites (HDMs), pet allergens, and environmental tobacco ... they were advised to remove pets from the home and to eliminate exposure to environmental tobacco smoke. Mothers were advised ... Incidence of skin test results positive to one or more inhalant allergens was similar in both groups (4.4% in the intervention ... and skin test results positive for common inhalant allergens. Thirty-eight (15.1%) of the 251 infants assessed in the ...
Effects of physical interventions on house dust mite allergen levels in carpet, bed, and upholstery dust in low-income, urban...
Dust/adverse effects. *Dust/analysis*. *Environmental Exposure/prevention & control*. *Floors and Floorcoverings ... House dust mite allergen exposure is a postulated risk factor for allergic sensitization, asthma development, and asthma ... Homes with high levels of house dust mite allergen (Der f 1 + Der p 1 , or = 10 microg/g dust by enzyme-linked immunosorbent ... Effects of physical interventions on house dust mite allergen levels in carpet, bed, and upholstery dust in low-income, urban ...
Educating Students about indoor Environmental Health Risks
Variability of house dust mite allergen exposure in dwellings Kuhlisch, Eberhard; Leupold, Wolfgang; Hirsch, Thomas; Soldan, ... The variability of repeated house dust mite (HDM) allergen determinations at the same site within 3-24 months was evaluated on ... Environmental health aspects of exposure to IAP; Details of exposure and health effects needed for successful intervention ... Indoor air pollution and childhood asthma: Effective environmental interventions. Etzel, Ruth A. // Environmental Health ...
Eotaxin Represents the Principal Eosinophil Chemoattractant in a Novel Murine Asthma Model Induced by House Dust Containing...
... environmental intervention to reduce cockroach allergen exposure in inner-city homes. J. Allergy Clin. Immunol. 103: 501. ... In an effort to locate a house containing dust with a high level of cockroach allergen, house dust was collected from 10 houses ... Assays for six different indoor allergens including two house cockroach allergens (Bla g1 and Bla g2), two house mite allergens ... Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk ...
PRIME PubMed | House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the...
PubMed journal article House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses ... Children with asthma have a high prevalence of environmental allergies, especially to indoor allergens. The relationships of ... For house dust mites, the higher the level of allergen exposure, the more likely patients were to have positive allergy skin ... For house dust mites, the higher the level of allergen exposure, the more likely patients were to have positive allergy skin ...
Asthma Risk Factors
... particularly cat and dog allergens), dust mites, cockroaches, fungi, and mold. Changes that have made houses more "energy- ... Environmental Factors and Asthma. Indoor air pollution such as cigarette smoke, mold, and noxious fumes from household cleaners ... Even more findings link secondhand smoke exposure with the development of asthma in early life. ... One nationwide study showed levels of bacterial toxins called endotoxins in house dust were directly related to asthma symptoms ...
This has implications for the medical treatment and for the environmental management of asthma. ... Asthma is now known to be a disease of airway inflammation resulting from a complex interplay between environmental exposures ... House dust mites, cockroaches, mold and animal dander have been identified as the principal allergens that trigger asthma ... Reducing exposure to environmental allergens and pollutants will reduce the frequency and severity of attacks for children with ...
Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children
These findings suggest that concomitant exposure to high levels of certain allergens and bacteria in early l … ... In inner-city environments children with the highest exposure to specific allergens and bacteria during their first year were ... the bacterial content of house dust collected in the first year of life. Associations were determined among environmental ... Environmental assessments included allergen exposure and, in a nested case-control study of 104 children, ...
NIOSHTIC-2 Search Results - Full View
Cockroaches and dust mites are common environmental allergens for children and young adults. Approximately 8% of the U.S. ... to house dust mites. Exposure to cockroaches, mites and multiple other species of insects can cause work-related allergies and ... Workplace exposures to insects causing allergic disease has occurred where the insects are part of the production process (fish ...
CDC - Asthma - Potentially Effective Interventions for Asthma - Bibliography
Effects of physical interventions on house dust mite allergen levels in carpet, bed, and upholstery dust in low-income, urban ... Parent-reported environmental exposures and environmental control measures for children with asthma. Arch Pediatr Adolesc Med ... D, Custovic A. Control of exposure to mite allergen and allergen-impermeable bed covers for adults with asthma. N Engl J Med ... environmental intervention to reduce cockroach allergen exposure in inner-city homes. J Allergy Clin Immunol 1999;103:501-6. ...
Skin therapy 1 Flashcards by Emily Stacey | Brainscape
How well can allergens be avoided 1. fleas - possible?. 2. food - YES. 3. environmental - not really, house dust mites (dead ... can still be allergenic), epithelia of different species (only if exposure can be limited), pollens (seasonal) ... remove allergens from skin. - improve skin/coat hygiene and care. - efficacy rarely documented. - owner compliance important ... injection of allergen extract SC at increasing quantities and intervals to patients with AD. - PEOPLE: decreases inflammatory ...
The reproducibility and sample size requirements of exercise-induced bronchoconstriction measurements | European Respiratory...
Subjects were not knowingly exposed to other environmental allergens (except house dust mite) for ≥2 weeks prior to any study ... Atopic subjects were not studied during periods associated with seasonal environmental allergen exposure. ... Reproducibility of allergen-induced early and late asthmatic responses. J Allergy Clin Immunol 1995;95:1191-1195. ... similar to those provided previously for allergen and methacholine challenges 22, 23. Finally, the per cent fall and AUC ...
House dust mite allergen in pillows | The BMJ
... these had been used together on the same adult bed for more than six months to ensure that the environmental exposures of the ... of patients with severe asthma have a positive skin prick test to house dust mite allergen,3 and exposure to mite allergen is a ... Geometric means of total and relative weight of house dust mite allergen Der p I in fine dust taken from pillows with synthetic ... the major allergen of the house dust mite Dermatophagoides pteronyssinus.. Methods and results. In December 1995 we took dust ...
Environmental Health Perspectives - Exposures Related to House Dust Microbiota in a U.S. Farming Population
First national survey of lead and allergens in housing: survey design and methods for the allergen and endotoxin components. ... House dust contains a wide range of microorganisms. The house dust microbiota is influenced by environmental factors and, in ... We examined the relationship of house dust endotoxin with both farm and nonfarm exposures using linear regression with exposure ... 2015) are associated with endotoxin concentration in house dust. However, no studies have examined how house dust endotoxin ...
Indoor Pollutants Linked to Asthma Symptoms in Children
An allergy is an exaggerated response from the immune system to a substance such as dust, pollen, pet dander or mold. ... "Exposure to nitrogen oxide emitted by unflued gas appliances indoors and exposure to house dust mites in bed can exacerbate ... Indoor nitrogen dioxide levels were measured at home and school, while levels of house dust mite allergen were measured in dust ... The cause of asthma is still uncertain, but environmental factors may play an important role in triggering asthma attacks. ...
2001 Annual Report | Research Project on Asthma | Research Project Database | Grantee Research Project | ORD | US EPA
... prenatal and/or postnatal exposure to home allergens (cockroach, house dust mite, and rodent) and environmental tobacco smoke ( ... environmental health hazard, growth & development, acute exposure, developmental disorders, disease, exposure assessment ... In many cases, allergen-induced proliferation occurred in cord blood in the absence of allergen-induced proliferation in ... risk from home allergens is increased by co-exposure to the air pollutants (ETS, PM2.5 and DEP); and (3) impaired nutritional ...
Short cigarette smoke exposure facilitates sensitisation and asthma development in mice | European Respiratory Society
Most asthma begins in early childhood after sensitisation and re-exposure to ubiquitous environmental allergens, such as house ... House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med 2009; 15: 410- ... Kinetics of allergen release from house dust mite Dermatophagoides pteronyssinus. J Allergy Clin Immunol 1986; 77: 24-31. ... Interaction of cigarette smoke and house dust mite allergens on inflammatory mediator release from primary cultures of human ...
Asthma & Allergy - National Asthma Council Australia
Exposure (sensitisation) to environmental allergens has also been associated with childhood asthma. House dust mite avoidance ... The greatest exposure to house dust mites is from your bedding. Ways to reduce house dust mite exposure include: *use mite- ... Examples of allergens include house dust mites, pollen, mould, and pet dander. Sensitivity to allergens can often be identified ... vacuum or dust, as this causes house dust mite allergens to become airborne ...
The Effectiveness of Indoor Allergen Reduction and the Role of Bronchial Thermoplasty in the Management of Asthma | Effective...
... often in response to specific exposures, resulting in respiratory symptoms. In the United States (U.S.), the current prevalence ... house dust mites (HDM), mice, cockroaches, mold, and others.6 Numerous interventions have been designed to reduce exposure to ... Household Allergens. (allergen/exp OR environmental exposure/exp OR health hazard/exp OR disease exacerbation/exp OR ... a different exposure control intervention for the same allergen(s); any exposure control intervention for a different allergen( ...
Allergen Avoidance | World Allergy Organization
Read the Allergen Avoidance article updated by Jay M Portnoy, MD and Kevin Kennedy, MPH for the WAO Allergic Disease Resource ... Environmental assessment and exposure control of dust mites: a practice parameter. Ann Allergy Asthma Immunol. 2013;111(6):465- ... House dust mite allergen in US beds: results from the First National Survey of Lead and Allergens in Housing. J Allergy Clin ... Airborne dust mite allergens: comparison of group II allergens with group I mite allergen and cat-allergen Fel d I. J Allergy ...
Frontiers | The Role of Sensitization to Allergen in Asthma Prediction and Prevention | Pediatrics
Despite the conductance of different studies regarding the potential role of allergen avoidance for the primary prevention of ... Despite the conductance of different studies regarding the potential role of allergen avoidance for the primary prevention of ... They also do not recommend any measures for the reduction of house dust mite exposure for primary prevention purposes. However ... to the initial level of indoor HDM allergen, and possibly to genetic or other environmental co-factors (67). ...
Allergic Reaction? -Doctors Lounge(TM)
b) Environmental factors: Exposure to pollen, house-dust, buffalo dander, fungi, change in temperature, etc. are known exciting ... a) Allergens: A large number allergens have been identified as causative agents for some cases of urticaria. It may be noted ... food allergens: Milk, cheese, egg, protein products, wheat, cereals, certain daals as used in India, peas, orange, fish, ...
PRIME PubMed | Risk of wheezing associated with house-dust mite allergens and indoor air quality among three-year-old children....
Risk of wheezing associated with house-dust mite allergens and indoor air quality among three-year-old children. Kraków inner ... PreschoolCohort StudiesDustEnvironmental ExposureEnzyme-Linked Immunosorbent AssayFamily CharacteristicsFemaleFungiHumans ... Exposition and sensitisation to indoor allergens, house dust mite allergen and cat allergens]. ... Relationship of house-dust mite allergen exposure in childrens bedrooms in infancy to bronchial hyperresponsiveness and asthma ...
Process for manufacturing pharmaceutical composition comprises of mycobacterium w in the treatment of asthma (obstructive lung...
It includes measures to control house dust mite antigen, animal danders, avoidance of exposure to environmental factors ... Coughing, wheezing, tight chest, difficult breathing or an asthma episode may result following exposure to allergen. ... Other precipitating factors include infection, exercise, occupational and environmental exposures, drugs, air pollution, and ... These changes commonly occur in response to changes in the environment including weather, allergens (such as dog or cat dander ...
MitesPollenCockroachesPollensIrritantsFood allergensPollutantsOutdoor allergensAirborne allergensSymptomsDanderAtopySensitisationMoldsAllergyEndotoxinSporesSpecific allergensMajor allergensRespiratoryTriggersMoldSensitizationConcentrationsTobaccoSensitivityPrevalenceProteinsInflammationCockroach allergensImmunotherapyPotential allergensOccupationalDifferent allergensAntibodiesPollutionDERMATOPHAGOIDESAntigensRepeated house dustAvoidance measuresLevels of cockroachImmuneAtopic dermatitisMicrobialAllergic diseaseChildhoodIrritant exposureReduce exposureClinically relevantAllergiesInflammatoryParticularly house dustSource of allergensAttacksBacteriaAmount of allergenMould
- The purpose of the trial is to asses the efficacy and safety of sublingual annual immunotherapy in children with bronchial asthma and/or allergic rhinitis allergic to house dust mites. (bioportfolio.com)
- A Retrospective Study of Clinical Response Predictors in Subcutaneous Allergen Immunotherapy With House Dust Mites for Allergic Rhinitis. (bioportfolio.com)
- House dust mites (HDM) are major allergens that cause allergic rhinitis (AR). (bioportfolio.com)
- Allergen immunotherapy has been shown to be an effective treatment for local allergic rhinitis (LAR) to house dust mites. (bioportfolio.com)
- Sensitivity to House Dust Mites Allergens with Atopic Asthma and Its Relationship with CD14 C(-159T) Polymorphism in Patients of West Bengal, India. (bioportfolio.com)
- Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. (bioportfolio.com)
- Family of house dust mites, in the superfamily Analgoidea, order Astigmata. (bioportfolio.com)
- Important perennial allergens include house dust mites, indoor molds, animal dander and occupational allergens. (aafp.org)
- The relationships of exposure to indoor allergens (dust mites, cat, dog, cockroach, and molds) and other host factors to allergy sensitization have not been evaluated simultaneously in a large cohort. (unboundmedicine.com)
- Patients' sensitivities to house dust mites (Dermatophagoides farinae and Dermatophagoides pteronyssinus), cats, dogs, cockroaches, and molds were examined for relationships to demographic variables, home dust allergen exposures, number of other positive allergy skin test responses, total serum IgE levels, and smoking in the home. (unboundmedicine.com)
- Sources of other indoor allergens include animal proteins (particularly cat and dog allergens), dust mites , cockroaches, fungi, and mold. (webmd.com)
- House dust mites, cockroaches, mold and animal dander have been identified as the principal allergens that trigger asthma symptoms. (news-medical.net)
- Cockroaches and dust mites are common environmental allergens for children and young adults. (cdc.gov)
- Approximately 8% of the U.S. population have a positive skin prick test to cockroaches and 10% to house dust mites. (cdc.gov)
- Further studies are needed to confirm our findings, and then to determine whether pillows with synthetic fillings preferentially retain allergen or support greater infestation with mites. (bmj.com)
- Exposure to nitrogen oxide emitted by unflued gas appliances indoors and exposure to house dust mites in bed can exacerbate asthma in children," Dr. Nitschke and colleagues conclude. (health.am)
- Most asthma begins in early childhood after sensitisation and re-exposure to ubiquitous environmental allergens, such as house dust mites (HDMs), moulds, plant pollen or animal dander. (ersjournals.com)
- The most common indoor allergens that have been shown to trigger symptoms in patients with asthma and rhinitis are pets (cats, dogs), rodents (mice, rats), cockroaches, dust mites and molds. (worldallergy.org)
- Dust mites are found in homes that have sufficient humidity to support their growth. (worldallergy.org)
- Dust mites require humidity to survive. (worldallergy.org)
- For homes in arid climates, dust mites are almost nonexistent. (worldallergy.org)
- An acaricide such as benzyl benzoate can kill dust mites when applied to carpeting and upholstered furniture. (worldallergy.org)
- Sensitization to house dust mites is an important risk factor for asthma exacerbations and the development of asthma. (cdc.gov)
- House dust samples from 76 Guangzhou families and 80 Conghua families were obtained to analyze levels of endotoxins, house dust mites, and cockroach allergens. (uni-muenchen.de)
- House dust mites are tiny insects that feed on the dead flakes of human skin. (naturalcures.com)
- Rhinitis is not caused by the dust mites themselves, but by a chemical found in their excrement. (naturalcures.com)
- Dust mites are present all year round, although their numbers tend to peak during the winter. (naturalcures.com)
- There is conflicting evidence with regard to the role of indoor pollutants such as maternal smoking, 6 method of cooking and heating, 7 8 and allergens 9 10 such as dust mites and pet allergens in relation to asthma and wheeze. (bmj.com)
- As a matter of fact, IL-33 was shown to detect 14 different allergens tested, which include some present in ambient air (i.e. pollen, house dust mites, and fungal spores) and others associated with occupational asthma (like subtilisin, found in detergents). (healthcanal.com)
- Analysis of expression and amino acid sequence of the allergen Mag 3 in two species of house dust mites-Dermatophagoides farinae and D. pteronyssinus (Acari: Astigmata: Pyroglyphidae). (aaem.pl)
- House dust mites (Acari: Pyroglyphidae) in the cities of Gdańsk and Gdynia (northern Poland). (aaem.pl)
- Risk of exposure to house dust pyroglyphid mites in Poland. (aaem.pl)
- Rising levels of vehicle pollution, increased concentrations of house dust mites in carpeted, centrally heated and insulated homes, dramatic shifts in diets, more sedentary lifestyles, and the psychological stress associated with hectic modern lives all may have contributed. (zocalopublicsquare.org)
- Common indoor pollutants are dust, house mites, animal dander (dog- and cat hair), cockroaches and molds. (seattlepi.com)
- Atopic dermatitis in dogs and cats can develop in response to normally harmless substances like grass, mould spores, house dust mites, and other environmental allergens. (bowwowinsurance.com.au)
- Exposure to second-hand tobacco smoke, combustion-derived air pollutants, house dust mites, fungal spores, pollens and pet dander deserve regular attention during follow-up according to most task force members. (ersjournals.com)
- Sensitivity to mites was dominating only in the south, animal dander allergens dominated in the north. (diva-portal.org)
- Current level of exposure at home to house dust mites and storage mites was associated with sensitivity, even at low levels, in contrast to animal allergens at home. (diva-portal.org)
- Other mites as well as insects are potential new allergen sources. (diva-portal.org)
- The home environment contains allergens from animal dander as well as mites and insects. (diva-portal.org)
- The outdoor climate has an influence on the indoor climate in the number and species of mites found, but in homes with hi!ih humidity mite allergens may reach very high levels also in regions where mites normally are not founs, such as the northern part. (diva-portal.org)
- The indoor allergy season occurs all-year-round and is caused by pollen, indoor pets such as cats and dogs, house dust mites, and even cockroaches. (didyouknow.org)
- According to a 1999 article by the President's Task Force on Environmental Health Risks and Safety Risks to Children's, "Asthma and the Environment: A Strategy to Protect Children," the most common environmental triggers that cause allergies and asthma in children are animal dander, mold, cockroaches and house dust mites, and they can affect adults, too. (didyouknow.org)
- And, house dust mites are "one of the most powerful biological allergens," says the Environmental Protection Agency (EPA). (didyouknow.org)
- Because we spend about 90 percent of our time indoors and more than half of that time in our homes, it's important to control our exposure to house dust mites and maintain a high indoor air quality. (didyouknow.org)
- According to the EPA you can control some of the biological contaminants, like house dust mites, by controlling the relative humidity level in a home. (didyouknow.org)
- House dust mites, the source of one of the most powerful biological allergens, grow in damp, warm environments. (didyouknow.org)
- Mites are microscopic arachnids related to ticks and spiders, live in house dust, and feed off the scales shed from human skin. (didyouknow.org)
- All homes have dust mites, but the amount of moisture in a home determines the number of dust mites present - the more moisture in a home, the more dust mites present. (didyouknow.org)
- One of the best ways to keep dust mites to a minimum is to keep your home clean. (didyouknow.org)
- While vacuuming keeps your dust mite problems in control, it does not kill them - only professionally cleaning your carpet removes dust mites from carpets. (didyouknow.org)
- Research indicates that carpets in indoor environments act as a collector for biological allergens, like dust mites, and keeps them out of your breathing zone. (didyouknow.org)
- It is most commonly triggered by one or more types of environmental allergens such as dust mites, pollens, and molds. (whole-dog-journal.com)
- Generally harmless materials like pollens, grass, mould spores, house dust mites, and other environmental allergens can bring on sensitive reactions. (aaps.org.au)
- Much information (and misinformation) has appeared in recent years about house dust mites. (illinois.gov)
- Virtually invisible to the naked eye, house dust mites are nevertheless real. (illinois.gov)
- It has been shown that, like cockroaches, dust mites and their feces can become airborne and are one of the most common indoor allergens. (illinois.gov)
- That is, most persons diagnosed as being allergic to "house dust" are actually allergic to the dust mites whose bodies and feces are major components of dust. (illinois.gov)
- Roaches and dust mites have also been implicated in triggering asthma attacks. (illinois.gov)
- But, unlike rodent mites, itch mites and chiggers, skin irritation is rarely caused by exposure to dust mites. (illinois.gov)
- Although they may "hitchhike" on clothing, dust mites do not live on people. (illinois.gov)
- Upholstered furniture, pillows and mattresses typically harbor more dust mites than carpeting. (illinois.gov)
- Three types of rodent mites readily bite humans: the house mouse mite (Liponyssoides saguineus) , spiny rat mite (Laelaps echidnina) and tropical rat mite (Ornithonyssus bacoti) . (illinois.gov)
- These include house dust mites, pet dander, and molds. (bmc.org)
- House dust mites constitute an important indoor allergen ( Der p 1 ). (pubmedcentralcanada.ca)
- From dust mites to pet dander, we walk you through the common triggers for asthma and allergic rhinitis and show you how to manage symptoms. (nationaleczema.org)
- Dust mites are microscopic creatures or tiny bugs found in house dust that can live everywhere indoors from mattresses and pillows to upholstered couches and carpets. (nationaleczema.org)
- Cleaning your home regularly can help reduce your exposure to dust mites. (nationaleczema.org)
- Dust mites, animal dander, molds, and pollen are among the most common environmental triggers of asthma attacks and allergy symptoms. (mercola.com)
- The airborne allergens also include: bacteria, house dust mites, epidermis of housepets, allergens of some food products and insect venom. (aaem.pl)
- From the study participants' blood samples, the research team measured allergy antibodies to house dust mites, grass, cats and dogs. (reuters.com)
- About 30 percent of participants had allergies, mostly to grass and house dust mites, and about a third had lived on a farm during childhood. (reuters.com)
- Studies with pollen allergen immunotherapy are limited to observational studie. (bioportfolio.com)
- Some people only experience allergic rhinitis for a few months at a time because the allergens they are sensitive to, such as tree or grass pollen, are only produced at certain times of the year. (naturalcures.com)
- Allergic rhinitis is caused by an allergic reaction to an allergen, such as pollen, dust and certain animals. (naturalcures.com)
- Pollen is considered a source of not only allergens but also immunomodulatory substances, which could play crucial roles in sensitization and/or the exacerbation of allergies. (jimmunol.org)
- Pollen grains of trees of the Cupressaceae family including the Taxodiaceae, such as Japanese cedar ( Cryptomeria japonica ), Japanese cypress ( Chamaecyparis obtuse ), Cupressus species, and Juniperus species, are relevant sources of allergens ( 2 , 3 , 5 ). (jimmunol.org)
- In addition to the function of pollen grains as carriers of allergen proteins, pollen-derived substances could exhibit immunomodulatory effects. (jimmunol.org)
- Underlying these trends is an increase in allergic reactions of all types: modern populations appear to be more sensitive to environmental triggers such as animals, foods, and pollen. (zocalopublicsquare.org)
- Dogs with access to the outdoors may introduce outdoor allergens such as mold and pollen with larger animals tracking in more of these allergens. (wikipedia.org)
- Pollen, the airborne allergen behind hay fever, is one of the most common aero-allergens and also one of the most difficult to avoid. (nationaleczema.org)
- The most prominent hypotheses explaining the associations are that pollen grains rupture by osmotic shock in rainwater, releasing allergens, and that gusty winds from thunderstorm downdrafts spread particles and/or aeroallergens, which may ultimately increase the risk of asthma attacks. (mercola.com)
- The conditions occurring at the onset of a thunderstorm might expose susceptible people to a rapid increase in concentrations of pollen allergens in the air that can readily deposit in the lower airways and initiate asthmatic reactions. (mercola.com)
- Although the condition is relatively uncommon, it's known to strike without warning, so if a thunderstorm is coming, stay indoors and close up your windows to avoid unnecessary exposure to ruptured pollen grains. (mercola.com)
- Characterisation of pollen allergens. (aaem.pl)
- The most frequent allergens from thenatural environment are inhalant ones present in pollen grains, mould fungi spores and in fragments ofmycelial hyphae. (aaem.pl)
- Many of them are resistantto pH changes and high temperature, even up to 100 degrees C. Apart from pollen grains, allergens canoccur in other parts of plants: roots, stems, leaves, seeds or fruit, in substances excreted by plants,such as juice and volatile oils, or in other bioaerosols of plant origin, e.g. fluids released duringtreatment of some crops. (aaem.pl)
- From among factors conducing pollen allergythe most important are genetic and environmental ones (air pollution, exposure to allergens, infectionsof respiratory tract, diet) and microflora of pollen grains. (aaem.pl)
- In a randomized controlled study, the induction of a flare-up by grass pollen exposure in sensitized atopic dermatitis patients could be demonstrated for the first time. (ovid.com)
- The associations between exposure, sensitisation, and asthma have suggested that house dust mite, 1 2 animal dander, 3 4 cockroaches, 5 pollens, 6 and mould spores 7 have a causal role in development. (bmj.com)
- Your parents strived to prevent allergic disease by reducing your childhood exposure to common allergens as house dust mite, cow's milk, peanuts, cockroaches, pets and diesel-exhaust fumes, which possibly delayed the onset of your allergy, but now you have fully developed asthma. (asthmaallergieschildren.com)
- Tree, grass and weed pollens are common seasonal allergens. (aafp.org)
- Avoidance relies on preventing pollens from getting into the house and on minimizing seasonal outdoor exposure. (dovepress.com)
- No, except that food allergies don't change with the seasons, whereas environmental allergies sometimes do, depending on the exposure to the allergen (pollens, house dust, etc. (animalhealthfoundation.net)
- The most commonly incriminated allergens are fungal spores and pollens, but barn dust is also rich in dust from shavings, sawdust, manure, hay, animal hair and dander, silica from dirt in indoor arenas, and endotoxin. (merckvetmanual.com)
- Because our lungs are used to breathing in air with irritants, such as bacteria, viruses, pollens, and dusts, all day every day, they've developed ways of dealing with these things, and normally, an inflammatory response does not occur. (news-medical.net)
- In susceptible individuals, it causes bronchial hyper respon-siveness (BHR), which results into inherent tendency of the airways to narrow in response to various stimuli (eg, environmental allergens and irritants), causing symptoms including wheezing, breathlessness, chest tightness, and cough, particularly at night or after exercise. (indmedica.com)
- The American Academy of Pediatrics has published a book about childhood environmental health problems, which states: "Avoiding environmental allergens and irritants is one of the primary goals of good asthma management" [AAPCEH 2003]. (cdc.gov)
- Substantial changes in our environment and lifestyles have probably increased our exposure to allergens and irritants that trigger attacks. (zocalopublicsquare.org)
- they must also learn what allergens or irritants to avoid. (zocalopublicsquare.org)
- This review summarises the literature on practical aspects of monitoring including adherence to treatment, inhalation technique, ongoing exposure to allergens and irritants, comorbid conditions and side-effects of treatment, as agreed by the European Respiratory Society Task Force on Monitoring Asthma in Childhood. (ersjournals.com)
- It has been proposed that MIECs could contribute to reduce patient exposure to many allergens and irritants, among them, house dust mite allergens, formaldehyde or molds. (clinicaltrials.gov)
- Recurrent airway obstruction (chronic obstructive pulmonary disease [see Recurrent Airway Obstruction in Horses ]), and noninfectious inflammatory airway disease are associated with airway hypersensitivity to environmental allergens and irritants and exposure to organic dust. (merckvetmanual.com)
- Environmental exposure to food allergens may be a risk factor for cutaneous sensitization. (bioportfolio.com)
- 1 Exposure to aeroallergens and sensitisation to food allergens has been shown to increase risk and severity of AE. (gponline.com)
- 8 Early exposure to cows' milk, egg protein, and other food allergens may cause food allergy and atopic eczema. (bmj.com)
- 13 Our study aimed for the first time to control for both variables-food allergens and house dust mite exposure. (bmj.com)
- Ways to control indoor allergens and pollutants. (ebscohost.com)
- Whether long term exposure to these pollutants can actually contribute to the development of asthma is not known. (news-medical.net)
- Reducing exposure to environmental allergens and pollutants will reduce the frequency and severity of attacks for children with asthma, reduce their need for medicine, and improve their lung function. (news-medical.net)
- Increased levels of two major indoor air pollutants - nitrogen dioxide and house dust mite - are responsible for worsening symptoms in children with asthma, reports a study in the May Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM). (health.am)
- For both indoor air pollutants, higher exposure levels were linked to increased asthma symptoms. (health.am)
- House dust mite allergen and nitrogen dioxide are important indoor air pollutants. (health.am)
- In light of the strong evidence that the extent of health effects is dose dependent, exposure [to indoor air pollutants] should be minimized," the researchers write. (health.am)
- Exposure to indoor and outdoor air pollutants may increase an individual's risk for morbidity and mortality from a variety of different conditions in multiple organ systems. (renalandurologynews.com)
- Several factors related to specific pollutant characteristics and patterns of exposure determine the likelihood of injury from inhalation of indoor or outdoor air pollutants. (renalandurologynews.com)
- Exposure to indoor pollutants represents a potentially modifiable cause of allergic sensitization and asthma. (indmedica.com)
- Environmental pollutants such as car exhaust and passive smoke can trigger attacks of asthma as well as viral infections. (hstalks.com)
- These communities also have disproportionately heavy exposure to environmental pollutants, which may contribute to these adverse health outcomes. (epa.gov)
- They include exposure to allergens in nature as well as man-made pollutants, like traffic exhaust fumes, household chemicals, pesticides, cigarette smoke (including second-hand smoking) and the likes. (seattlepi.com)
- In addition to adverse reactions to allergens and pollutants, there can be allergies to certain foods involved. (seattlepi.com)
- The health risks to babies from pollutants in house dust may be 100 times greater than for adults. (ei-resource.org)
- The concentration of pollutants in house dust may be 2-32 times higher than that found in the soil near a house. (ei-resource.org)
- Infants receive their highest exposure to pollutants in dust at home, where they spend the most time, and where the family has the most mitigation control. (ei-resource.org)
- We believe that proven intervention methods can reduce the exposure of infants to pollutants in house dust, while recognizing that much remains to be learned about improving the effectiveness of such methods. (ei-resource.org)
- Smaller dogs will also leave fewer environmental pollutants containing dog dander and dog allergens (reduced fecal matter, urine and saliva). (wikipedia.org)
- We have not reached a medicinal solution yet, but this study reveals that there could be a tangible therapeutic target and that anti-oxidative treatment could be beneficial to asthmatic patients, especially those with increased exposure to air pollutants. (medica-tradefair.com)
- The multi-disciplinary forum will present data on the marked global increase of allergic diseases including asthma, food allergies, allergic rhinitis, skin allergies, anaphylaxis, drug allergies, and occupational allergies and also include presentations on how allergy interacts with many other environmental factors such as pollutants, infections, lifestyle and diet which increase the impact on chronic non-communicable diseases. (prweb.com)
- Innate immune activation through exposure to indoor and outdoor pollutants is emerging as an important determinant of asthma severity. (nih.gov)
- Numerous exposures such as viral infections, indoor as well as outdoor allergens and ambient pollution contribute to the development of asthma in childhood and the persistence of asthma in adulthood. (medica-tradefair.com)
- Being exposed to viral infections, indoor and outdoor allergens and pollution contributes to asthma in childhood and asthma in adulthood. (doctorshealthpress.com)
- The most common airborne allergens that cause rhinitis are described below. (naturalcures.com)
- And they're on the right track, given the IPBS team's discovery of a single mechanism for detection of airborne allergens by IL-33. (healthcanal.com)
- By professionally cleaning your carpets, you are preventing the airborne allergens from entering your breathing zone, minimizing the risk of asthma attacks and allergy reactions. (didyouknow.org)
- Sensitisation to airborne allergens might be involved in the underlying mechanisms of severity. (bmj.com)
- Lee and Arriola discuss three therapies: (1) allergen avoidance, (2) pharmacologic treatment to prevent and control symptoms and (3) allergen immunotherapy for recalcitrant patients. (aafp.org)
- Reducing exposure to these allergens has been shown not only to reduce asthma symptoms and the need for medication, but also to improve lung function. (news-medical.net)
- Led by Monika Nitschke, Ph.D., of University of Adelaide, Australia, the researchers examined the relationship between nitrogen dioxide and dust mite levels and asthma symptoms in 174 asthmatic schoolchildren. (health.am)
- Among children allergic to house dust mite, higher levels of mite allergen were also related to increased asthma symptoms. (health.am)
- The heater replacement study has demonstrated the health benefits of reducing indoor nitrogen dioxide levels - more research is needed to determine whether reducing exposure to house dust mite will reduce asthma symptoms. (health.am)
- Bronchoconstriction, inflammatory cell infiltration, and airway edema reduce airflow intermittently, often in response to specific exposures, resulting in respiratory symptoms. (ahrq.gov)
- Exposure to agricultural pesticides has been noted to aggravate asthmatic symptoms in farm workers ( 8 ). (scielosp.org)
- In children and adults, sensitive to indoor allergens, the severity of asthma symptoms may vary with the level of exposure. (cdc.gov)
- 20 016 children (mean age 7 years) and 13 266 adolescents (mean age 13 years) completed questionnaires on indoor exposures and respiratory symptoms/diseases. (bmj.com)
- The symptoms usually begin soon after exposure to an allergen. (naturalcures.com)
- Although life-threatening reactions may not be as common with environmental allergies, they can trigger severe asthma attacks or debilitating nasal and eye symptoms in allergic people. (parentscanada.com)
- When allergens enter the human respiratory tract, they release proteases that hack IL-33 molecules into extremely reactive pieces triggering the chain reactions behind allergy symptoms. (healthcanal.com)
- Asthma development and the precipitation of asthma symptoms is dependent on sensitivity to inhalation allergens, of which indoor allergens are of special interest because they are not seasonal. (diva-portal.org)
- One part of the thesis was a study on the importance of known indoor allergens on the sensitivity and asthmatic symptoms, the other part aimed at finding new potential allergens that may explain the symtomatology. (diva-portal.org)
- They answered a questionnaire which recorded their medication and symptoms, computed to an asthma score, their indoor environment, allergic reactions to dust and animal contacts. (diva-portal.org)
- Indoor allergens are important for the sensitivity and symptoms of asthmatic children with perennial symptoms. (diva-portal.org)
- Exposure to environmental allergens can result in the onset of symptoms, such as wheezing, coughing, and shortness of breath, which can be controlled by steroid therapies and allergen avoidance. (hindawi.com)
- Are there specific symptoms that are different from the symptoms of an environmental allergy? (animalhealthfoundation.net)
- The onset of asthma symptoms are often triggered by allergens. (boehringer-ingelheim.cz)
- Allergy symptoms appear when the immune system reacts to an allergic substance (allergen) that has entered the body as though it were an unwelcome invader. (bmc.org)
- Symptoms caused by these allergens often worsen in the winter when the house is closed up, due to poor air ventilation. (bmc.org)
- Consider purchasing dust mite covers made specifically for mattresses and pillows that can help fight allergy symptoms. (nationaleczema.org)
- Both the frequency and severity of asthma symptoms can be reduced by the use of medications and by reducing exposure to the environmental triggers of asthma attacks. (news-medical.net)
- It can also be triggered by workplace-related allergens such as flour and grain dust, latex, and animal allergen (e.g. urine, dander). (nationalasthma.org.au)
- Animal dander allergens (pets, mice, rats) vary with geographic location. (cdc.gov)
- The significant allergens are proteins found in the dog's saliva and dander. (wikipedia.org)
- Individuals with dog allergy may also be at increased risk for human protein hypersensitivity with cross-reactivity of dog dander allergen and human seminal fluid. (wikipedia.org)
- Aoimal dander allergens were found in all homes, even in homes without pets. (diva-portal.org)
- 1 Pet dander, the source of allergens, is composed of tiny, even microscopic, proteins from flecks of skin shed by pets. (nih.gov)
- Dog allergens are also present in dander, as well as saliva, urine, and blood. (nih.gov)
- For all allergens studied, the degree of atopy, determined by the total number of positive skin test responses or by total serum IgE levels, is an important contributing risk factor for sensitization. (unboundmedicine.com)
- Atopy causes a heightened sensitivity to common allergens, especially those that are in food and in the air. (webmd.com)
- Differences in house dust bacterial content in the first year, especially reduced exposure to specific Firmicutes and Bacteriodetes, was associated with atopy and atopic wheeze. (nih.gov)
- Exposure to high levels of both allergens and this subset of bacteria in the first year of life was most common among children without atopy or wheeze. (nih.gov)
- When people with allergic tendencies (atopy) are exposed to allergens, they can develop an immune reaction that leads to allergic inflammation (redness and swelling). (nationalasthma.org.au)
- The data support the view that exposure to a higher level of HDM allergens increases the burden of respiratory diseases in the early childhood and the effect is independent of maternal atopy, ETS, and moulds in homes. (unboundmedicine.com)
- 14 We hypothesise that, in infants genetically predisposed to atopy, allergen exposure in infancy plays a critical role in the development of phenotypic manifestations. (bmj.com)
- Early detection of atopy and the causal allergens, including food, prevention of the development of viral infections, treatment of atopic dermatitis, allergic rhinitis, etc. are important components of primary prevention. (indmedica.com)
- The prevalence of wheeze, cough, and atopy was higher in children who had lived in more than one house during their lifetime. (bmj.com)
- This is not unusual given that we have Golden Retrievers (a breed that is genetically predisposed to atopy) and we live in the Midwest, an area with lots of allergens for hypersensitive dogs to react to. (whole-dog-journal.com)
- Epidemiological studies indicate that cigarette smoke exposure is a risk factor for increased sensitisation and asthma development. (ersjournals.com)
- The aim of this study was to examine the impact of cigarette smoke on sensitisation and allergic airway inflammation in response to a low dose of house dust mite (HDM), and to obtain potential mechanistic insights. (ersjournals.com)
- Mice were exposed to low doses of HDM extract combined with air or cigarette smoke exposure, either during allergen sensitisation or during the development of allergic airway disease. (ersjournals.com)
- In addition, short cigarette smoke inhalation, during the initial contact with HDM allergens, was sufficient to facilitate sensitisation and development of a complete asthmatic phenotype after rechallenge with HDM. (ersjournals.com)
- Short cigarette smoke exposure is sufficient to facilitate allergic sensitisation and the development of low-dose HDM-induced allergic asthma, possibly by affecting dendritic cell function. (ersjournals.com)
- The risk for sensitisation is strongly dependent on the level of allergen exposure [ 1 ]. (ersjournals.com)
- Smoking is even associated with increased sensitisation to HDM allergens [ 9 ] and appears to be a risk factor for new-onset asthma among children and adults [ 10 - 12 ]. (ersjournals.com)
- Most murine models, designed to characterise the complex interaction between smoking and allergic airway inflammation, have relied on the sensitisation to the "surrogate" allergen ovalbumin (OVA) [ 13 - 18 ]. (ersjournals.com)
- To explain the observed increase in asthma prevalence due to cigarette smoke exposure, we hypothesised that cigarette smoke may lower the threshold for sensitisation to HDM allergens. (ersjournals.com)
- We examined the effect of cigarette smoke on both sensitisation and ensuing asthma development and checked whether a few days of smoke exposure were sufficient to prime local sensitisation in the lymph nodes. (ersjournals.com)
- Familial predisposition to increased serum IgE antibodies and sensitisation to various allergens is seen in people with an 'atopic tendency' and an increased susceptibility to developing atopic eczema, asthma and allergic rhinitis. (gponline.com)
- Strict allergen avoidance in infancy in high risk children reduces the development of allergic sensitisation to house dust mite. (bmj.com)
- Indeed, there is growing epidemiological evidence that indoor allergen exposure, especially early in life, may contribute to the development of allergic sensitisation. (bmj.com)
- Thus, Priftis et al showed that the sensitisation rate to common environmental allergens, particularly house dust mite, was significantly higher in coastal regions of Greece than in urban areas, and suggested that this was due to the encouragement of mite growth by the high humidity levels found in coastal areas. (bmj.com)
- Most allergic reactions require a period of repeated exposure and skin sensitisation, which can take anywhere from 6 months to 2 years to develop. (bowwowinsurance.com.au)
- Although it is clear from a number of epidemiologic studies that sensitisation to indoor allergens and to the spores of Alternaria are risk factors for the development of asthma in both children and adults (22), detailed investigation is problematic. (phadia.com)
- To assess whether the severity of asthma is associated with sensitisation to airborne moulds rather than to other seasonal or perennial allergens. (bmj.com)
- However, the associations between sensitisation to different allergens and the severity of asthma have been poorly explored. (bmj.com)
- BACKGROUND Sensitisation to cat allergen (Fel d 1) is an important risk factor for asthma in the UK. (semanticscholar.org)
- Consequently, asthma has almost universally been regarded as an atopic disease involving allergen exposure, allergic (IgE mediated) sensitisation with a Th2 CD4+ lymphocyte response and subsequent IL-5 mediated eosinophilic airways inflammation, resulting in enhanced bronchial reactivity 3 and eventually in reversible airflow obstruction (asthma). (bmj.com)
- Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a populations-based cross-sectional study. (vidyya.com)
- Short cigarette smoke exposure facilitates sensitisation and asthma development in mice," EUROPEAN RESPIRATORY JOURNAL , vol. 41, no. 5, pp. 1189-1199, 2013. (ugent.be)
- Sensitization to indoor allergens and the spores of outdoor molds is a risk factor for the development of asthma in children and adults. (cdc.gov)
- Barns should be constructed to optimize ventilation and light, minimize exposure to dust and molds, provide temperature regulation, facilitate cleaning and disinfection, and provide ample space for each horse. (merckvetmanual.com)
- The purpose of the study is to test the efficacy of the combination treatment AllQbG10 in patients with perennial allergic rhinoconjunctivits due to house dust mite allergy in a double-bli. (bioportfolio.com)
- Immunotherapy of House Dust Mite Allergy. (bioportfolio.com)
- The role of other potential causes of CL such as allergy and environmental pollution has not been thoroughly investigated. (sigmaaldrich.com)
- We studied 1041 children aged 5 to 12 years with mild-to-moderate asthma to determine risk factors associated with having positive allergy skin test responses to indoor allergens. (unboundmedicine.com)
- TY - JOUR T1 - House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program. (unboundmedicine.com)
- In the multivariate Poisson regression analysis on the association between the occurrence of wheezing and exposure, a set of potential confounders, such as child's gender, maternal education, maternal allergy, older siblings, presence of moulds, house dampness, and environmental tobacco smoke (ETS) was taken into account. (unboundmedicine.com)
- House Dust Mite Allergy Under Changing Environments. (medworm.com)
- Another common form of allergy is caused by exposure to environmental allergens your cat either breathes in or absorbs through the skin. (pethealthnetwork.com)
- Mite allergy and mite exposure in Iceland. (aaem.pl)
- The tools provided to families during home visits, designed to reduce dust exposures, included vacuum cleaners with dirt finders and HEPA filtration, allergy control bedding covers, high-quality door mats, and HEPA air filters. (ei-resource.org)
- Even if you get a hairless dog, it's still going to produce the allergen," states Dr. Wanda Phipatanakul, chair of the Indoor Allergen Committee for the American Academy of Allergy, Asthma, and Immunology. (wikipedia.org)
- It is well established that most individuals with dog allergy also suffer with additional environmental allergies. (wikipedia.org)
- Once our dogs started to have daily swims, we found that this form of frequent bathing kept allergy signs at bay throughout the summer, simply by its ability to physically reduce exposure to allergens and to cleanse the skin. (whole-dog-journal.com)
- Allergy in man caused by exposure to mammals. (semanticscholar.org)
- They may include reducing exposure to allergens, medications, and allergy shots or drops. (bmc.org)
- Studies of dust in various homes has shown that the microbiome found in the dust is correlated to the risk of children in those homes developing allergy, asthma, or phenotypes connected to these ailments. (wikipedia.org)
- They also measured the amount of cat allergens in the children's homes and discovered that low-to-moderate amounts of cat allergen seemed to trigger allergy, but high amounts reduced both IgE antibodies and the likelihood of asthma. (vidyya.com)
- Furthermore, in a multivariate regression model examining clinical, behavioral, and household factors associated with peanut protein levels in the infant's bed dust, only household peanut consumption remained significant (Coefficient=0.492, P =0.020), the authors reported online in the Journal of Allergy and Clinical Immunology . (medpagetoday.com)
- Other treatment options include allergen immunotherapy or allergy shots that work like a vaccine. (nationaleczema.org)
- Patients should base a decision regarding allergy shots on how much time each year is spent suffering with allergy and how well medications and environmental controls are helping. (nationaleczema.org)
- Reuters Health) - Exposure to farms seems to reduce the risk of allergy sensitivity, even among adults, and living close to a livestock farm in particular might curb common allergies, a Dutch study suggests. (reuters.com)
- An aqueous extract was prepared from a house dust sample containing endotoxin and high levels of cockroach allergens. (jimmunol.org)
- These data describe a novel murine model of asthma-like pulmonary inflammation induced by house dust containing endotoxin and cockroach allergens and further demonstrate that eotaxin represents the principal chemoattractant for the recruitment of the pulmonary eosinophils. (jimmunol.org)
- Many taxa correlated with the concentration of house dust of endotoxin, commonly studied as a general marker of exposure to the farming environment. (nih.gov)
- 1 year of age (OR, 0.15 [95% CI, 0.08-0.32]) and dust endotoxin levels (OR, 0.69 [95% CI, 0.50-0.95]) were negatively associated with asthma. (uni-muenchen.de)
- Early life exposure to crop farming and high environmental endotoxin levels might protect the children from asthma in southern China. (uni-muenchen.de)
- Dust was collected for analysis of moulds, bacteria and endotoxin levels. (diva-portal.org)
- To model allergic lung inflammation in a dirty indoor environment, the team exposed a mouse model to a common environmental indoor allergen - house dust mite - as well as to endotoxin, a toxin released by bacterial cells. (thirdage.com)
- It is hypothesised that a major proportion of asthma is based on neutrophilic airway inflammation, possibly triggered by environmental exposure to bacterial endotoxin, particulate air pollution, and ozone, as well as viral infections. (bmj.com)
- In an earlier study, we found that infants were exposed to high levels of endotoxin and allergens (mite and cockroach) in their daycare centers. (healthcanal.com)
- Allergen and endotoxin exposure, infection and breastfeeding were compared to the instances of persistent wheezing in the young children. (healthcanal.com)
- Additionally, dust samples were collected from the bedding and floor of the infants' bedroom with testing for endotoxin content and major allergens done. (healthcanal.com)
- Analysis showed that allergen and endotoxin exposure and exclusive breastfeeding for six months showed no effect in the development of asthma. (healthcanal.com)
- Recently, Alternaria has been found in house dust samples in the absence of outdoor environmental mould spores (7). (phadia.com)
- Furthermore, the major allergens are secreted proteins, whereas the other allergens are intracellular proteins, and the latter are presented to the immune system in the spores of this mould, which are too large to reach the alveoli of the lung (18). (phadia.com)
- Furthermore, germination of spores significantly increases allergen release (but not all spores release allergens). (phadia.com)
- For example, Alt a 1, the major allergen, may be a minor contributor to the total amount of allergens released from spores, except when spores have germinated (20). (phadia.com)
- How the phenomena revealed in these results reflect the allergen content of spores in the air that we breathe has, however, not been fully elucidated. (phadia.com)
- It is one of the most common mold spores found in dwelling dust in both North America and Europe. (phadia.com)
- If you are allergic to mold, your immune system is overly-sensitive to specific mold spores and treats them as an allergen. (nationaleczema.org)
- In inner-city environments children with the highest exposure to specific allergens and bacteria during their first year were least likely to have recurrent wheeze and allergic sensitization. (nih.gov)
- These tests identify antibodies to specific allergens. (nationalasthma.org.au)
- 4 , ,10 ,17 ,21 Thus, the relative contribution of specific allergens or other residential exposures to asthma for children and adolescents in the United States is poorly defined. (aappublications.org)
- The presence of specific allergens, including the major allergens, depends very much on the growth conditions, and may vary during the growth cycle, being greater one day than another (18-19). (phadia.com)
- T cells directed to the two major allergens of house dust mite have been characterized to display a Th2, and moreover, a Th17 and Th2/Th17 phenotype in sensitized atopic dermatitis patients. (ovid.com)
- Supplementation of wild-type animals with L. johnsonii protected them against both airway allergen challenge or infection with respiratory syncytial virus. (pnas.org)
- We found that characteristic features of asthmatic inflammation developed only in animals that received particulates at the same time as respiratory sensitization, and were then chronically challenged with allergen. (biologists.org)
- The aim of the study was to describe the distribution of house-dust mite (HDM) allergens in homes of three-year-old children and to test the hypothesis whether the content of HDM allergens exceeding 2 microg/g of dust may be regarded as a risk level possibly affecting respiratory health in early childhood. (unboundmedicine.com)
- At the time of the house-dust collection, mothers were interviewed on the household characteristics and their children's respiratory health. (unboundmedicine.com)
- These exposures cause and/or exacerbate respiratory diseases and diseases in other organ systems. (renalandurologynews.com)
- The bronchial airway epithelial cell (BAEC) is the site for initial encounters between inhaled environmental factors and the lower respiratory system. (mdpi.com)
- To report on the relation between home mould and/or dampness exposure and respiratory disorders in a large sample of children and adolescents in Italy, accounting for age at time of exposure. (bmj.com)
- Respiratory disorders such as wheeze and asthma can often be explained by exposure to home mould/dampness, especially early in life. (bmj.com)
- A team of Inserm and CNRS researchers from the Institute of Pharmacology and Structural Biology-or IPBS (CNRS / Université Toulouse III-Paul Sabatier)-have identified a protein that acts like a sensor detecting various allergens in the respiratory tract responsible for asthma attacks. (healthcanal.com)
- Indoor Allergens and Allergic Respiratory Disease. (semanticscholar.org)
- Farming is actually one of the few environmental exposures consistently linked to respiratory allergies," she told Reuters Health by email. (reuters.com)
- In contrast to the limited understanding of the relationship of environmental exposures to the onset of asthma, the environmental triggers of asthma attacks for children with asthma have become increasingly well characterized. (news-medical.net)
- This is particularly important for asthma management, since the environmental management of asthma requires knowledge of asthma triggers and specific actions that can be undertaken to reduce exposure to these triggers. (news-medical.net)
- However, unlike other asthma triggers such as colds and flu, it might be possible to avoid or reduce your exposure to some allergen triggers of your asthma. (nationalasthma.org.au)
- The use of environmental interventions to treat patients with allergic disorders has long been promoted to reduce morbidity by reducing a patient's exposure to environmental triggers. (worldallergy.org)
- The idea is straight forward: A patient with asthma is evaluated for sensitivity to environmental triggers. (worldallergy.org)
- Once identified, an intervention is recommended that is targeted to reduce exposure to relevant triggers. (worldallergy.org)
- The problem is that patients may be sensitized to multiple environmental triggers many of which have no readily available means for measurement to determine exposure. (worldallergy.org)
- In addition, feasible interventions frequently are not able to reduce exposure to triggers sufficiently to improve asthma outcomes. (worldallergy.org)
- House dust mite proteins induce IgE-mediated responses and have direct proteolytic activity, which triggers inflammation. (gponline.com)
- Many such triggers are allergens to which the infant appears particularly vulnerable. (bmj.com)
- Identifying asthma triggers forms the basis of environmental secondary prevention. (dovepress.com)
- Nonallergenic triggers include viral infections, active and passive smoking, meteorological changes, occupational exposures, and other triggers that are less commonly involved. (dovepress.com)
- While epidemiological research has uncovered many of the most likely environmental triggers of asthma, isolating the precise cause in individual patients is more difficult. (zocalopublicsquare.org)
- Two large studies provide evidence that home visits to reduce the exposure of children with poorly controlled asthma triggers may return more than 100% on investment in 1 yr in reduced health costs. (ei-resource.org)
- It is caused due to genetic factors or environmental triggers, or a combination of both. (persistencemarketresearch.com)
- In contrast, levels of exposure to cat, dog, and mold allergens were not related to sensitization rates. (unboundmedicine.com)
- This relationship was not demonstrable for cat, dog, or mold allergens, possibly because of confounding factors. (unboundmedicine.com)
- This can be determined by first taking a detailed environmental history focusing on the presence of pets, reservoirs where dust mite and mold allergens can reside such as carpeting and upholstered furniture, any recent moisture-related problems, reported cleaning practices and frequency, and on whether the patient has observed evidence of cockroach or rodent infestation. (worldallergy.org)
- We investigated the ability of ambient environmental particulates to contribute to sensitization via the airways, and thus to the pathogenesis of childhood asthma. (biologists.org)
- Even exposure to low levels of mite allergen (0.020-2.0 microg/g) was found to be a significant risk factor for sensitization. (unboundmedicine.com)
- Levels of exposure determined by house dust analysis are important determinants of sensitization for dust mite and cockroach allergen. (unboundmedicine.com)
- Since first identified and sequenced in a guinea pig model ( 13 ), the C-C chemokine eotaxin has been considered the major eosinophil chemoattractant in various animal models of eosinophilic pulmonary inflammation ( 14 , 15 ) and in human tissues after allergen sensitization ( 16 , 17 , 18 ). (jimmunol.org)
- Associations were determined among environmental factors, aeroallergen sensitization, and recurrent wheezing at age 3 years. (nih.gov)
- Cumulative allergen exposure over the first 3 years was associated with allergic sensitization, and sensitization at age 3 years was related to recurrent wheeze. (nih.gov)
- The below results demonstrate a high rate of sensitization in newborns, and that for cockroach, dust mite, and tetanus, the presence of proliferation in response to allergen significantly differed between mothers and newborns. (epa.gov)
- 5]  Children who live in houses with concentrations of dust mite allergen greater than 2 mcg/g dust have an increased likelihood of mite sensitization and of developing asthma. (worldallergy.org)
- One possible mechanism is the increase in allergen production leading to more exposure and sensitization in susceptible individuals. (medworm.com)
- In the past, we hoped to decrease allergic sensitization through various dietary and environmental manipulations during pregnancy and early childhood. (parentscanada.com)
- Allergen avoidance strategies are difficult for patients with severe asthma with fungal sensitization (SAFS) due to the ubiquitous environmental presence of fungi. (hindawi.com)
- Sensitization to a species of house dust mite called D. Pteronyssinus was found in 27% of the children but this also had no association with persistent wheezing. (healthcanal.com)
- About 80% of dust mite and 15% of cat allergen samples were above the threshold values for sensitization of 2 and 1 μg/g, respectively. (pubmedcentralcanada.ca)
- Exposure to dust mite allergens is a known risk factor for sensitization and is a trigger for asthma attacks [ 4 ]. (pubmedcentralcanada.ca)
- Mechanistically, short CS exposure amplified DC-mediated transport of FITC-labelled HDM allergens to the intrathoracic lymph nodes and generated a local Th2 response.Short CS exposure is sufficient to facilitate allergic sensitization and the development of low dose HDM-induced allergic asthma, possibly through affecting dendritic cell function. (ugent.be)
- We compared pretreatment mean allergen concentrations and loads to posttreatment values and performed between-group analyses after adjusting for differences in the pretreatment means. (nih.gov)
- Older homes and homes whose occupants have lower incomes tend to have higher dust mite concentrations. (worldallergy.org)
- In low-income countries, exposure to smoke from biomass fuel combustion is widespread and typically occurs at high concentrations. (renalandurologynews.com)
- Cells were exposed to three different concentrations of lipopolysaccharide (LPS) or house dust mite allergen (HDM) or particulates extracted from side stream cigarette smoke (SSCS). (mdpi.com)
- Significant concentrations of Alternaria allergens, between 3.0 and 1,000 U/g of dust, have been found in house dust of allergic children, supporting the hypothesis that fungal allergen exposure is an important component in the pathogenesis of asthma (5-6). (phadia.com)
- A recent study found that at ground-level (50 cm) Alternaria spore concentrations are significantly higher in the presence of vegetation, suggesting that the individual's exposure to Alternaria, especially in the case of children, is underestimated by samples taken at roof-top level by a fixed volumetric collector (9). (phadia.com)
- But Alternaria is predominantly an outdoor allergen favouring damp spots, and most indoor concentrations may derive from outdoor primary sources. (phadia.com)
- Median or upper percentile concentrations in house dust of lead and several pesticides and PAHs may exceed health-based standards in North America. (ei-resource.org)
- in addition, they were advised to remove pets from the home and to eliminate exposure to environmental tobacco smoke. (cdc.gov)
- Environmental tobacco smoke is an important irritant that can trigger an asthma episode and possibly worsen the effects of allergens. (news-medical.net)
- Approximately 29% of households still permit exposure of children to secondhand smoke in the home on a regular basis and exposure to environmental tobacco smoke is so widespread that approximately 88% of all children have some level of documented exposure (Pirkle, 1996). (news-medical.net)
- Currently, the only universal recommendations we make for families at increased risk is to avoid environmental tobacco smoke, and to breastfeed infants for four to six months. (parentscanada.com)
- tobacco smoke, strong odors, pollution and environmental changes in temperature and humidity-can facilitate the identification of cases. (scielo.br)
- In the case of poorly controlled asthma other factors might be considered, such as persistent exposure to tobacco smoke or allergens. (ersjournals.com)
- A non-significant increased risk of childhood asthma was associated with self-reported family history of asthma, childhood environmental tobacco smoke exposure, and air pollution. (pubmedcentralcanada.ca)
- Sensitivity to allergens can often be identified via blood or skin tests. (nationalasthma.org.au)
- After you develop sensitivity to an allergen, whenever it comes into contact with the inside of your nose and throat, it will be detected by antibodies called immunoglobulin E (IgE). (naturalcures.com)
- Sensitivity to Alternaria , a potent allergen, has been increasingly recognised as a risk factor for the development, persistence, and exacerbation of asthma (8-13). (phadia.com)
- Skin tests and blood tests were used to assess sensitivity to indoor allergens. (diva-portal.org)
- In 2012, on the basis of several studies of dust mite immunotherapy, newly published guidelines suggested that doctors consider allergen immunotherapy in selected patients with atopic dermatitis if they have aeroallergen sensitivity, but it is not FDA approved," Wein said. (nationaleczema.org)
- The study doesn't prove whether or how exposure to farms might reduce allergic sensitivity. (reuters.com)
- Children with asthma have a high prevalence of environmental allergies, especially to indoor allergens. (unboundmedicine.com)
- This strong rise in asthma prevalence emphasises an important role for environmental and socio-economic conditions [ 2 ]. (ersjournals.com)
- Authors: Acevedo N, Zakzuk J, Caraballo L Abstract Environmental variations induced by industrialization and climate change partially explain the increase in prevalence and severity of allergic disease. (medworm.com)
- 2 This increase in prevalence has focused attention on the role played by environmental factors. (bmj.com)
- Describe the impact of occupational exposures on adult asthma prevalence. (cdc.gov)
- Having demonstrated in a previous study that the prevalence of wheeze is as high in the Scottish Highlands as in urban areas of the UK, 3 and in the absence of major outdoor pollution, we felt that this area was ideally situated for the study of indoor environmental factors which might be related to the prevalence of asthma. (bmj.com)
- Surprisingly, the prevalence of asthma and skin tests to common allergens was lower in the East. (sciencemag.org)
- The allergens originating from the natural environmentare usually proteins, being high-molecular compounds of molecular weight higher than 10 kDa. (aaem.pl)
- This study tested the concept that asthma-like pulmonary inflammation may be induced by house dust containing cockroach allergens. (jimmunol.org)
- Asthma is now known to be a disease of airway inflammation resulting from a complex interplay between environmental exposures and genetic and other factors. (news-medical.net)
- Wheezing and coughing triggered by dust mite allergen are linked to allergic reactions, while the breathlessness and chest tightness triggered by nitrogen dioxide are likely related to airway inflammation. (health.am)
- Re-duction of allergen exposure, leading to subsidence of inflammation and hyperactivity in bronchi belongs to sec-ondary prevention. (indmedica.com)
- The pollutant can exacerbate pre-existing airway inflammation, leading to increased airway hyper-responsiveness, which may persist after exposure ends. (cdc.gov)
- While undergoing stressful situations per se may not have a direct causal effect, it is clear that long-term exposure to stress can compromise the immune system and thereby aggravate airway inflammation among other responses. (seattlepi.com)
- Exposure to both stimuli triggered complex lung inflammation, including a phenomenon known as lung NETosis. (thirdage.com)
- Levy and colleagues found that in their model, NETosis and cytoplasts appeared to play a key role in triggering and amplifying an allergen-initiated neutrophilic immune response in lung inflammation. (thirdage.com)
- Using wild-type and transgenic mice expressing the human mannose receptor on smooth muscle cells, we explored the outcome of mannan administration during allergen exposure on the pathogenesis of fungal asthma through measurement of cardinal features of disease such as inflammation, goblet cell number, and airway hyperresponsiveness. (hindawi.com)
- Since airways inflammation, hyperresponsiveness, and GC hyperplasia are associated with the pathogenesis of SAFS, herein, we investigated a possible role for mannan in mitigating these characteristics when administered during allergen exposure. (hindawi.com)
- We showed that bacterial flagellin can be found in the house dust of patients with asthma and that this bacterial product exacerbates allergic airway inflammation in an allergen-specific mouse model of asthma. (nih.gov)
- Recent findings on immunological and clinical characteristics of adaptive immune responses to allergens in atopic dermatitis, but also on the identification of new, potentially relevant allergen sources might contribute to the development of effective treatment strategies 'customized' for allergic inflammation in atopic dermatitis in future. (ovid.com)
- Asthma represents a serious health problem particularly for inner city children, and recent studies have identified that cockroach allergens trigger many of these asthmatic attacks. (jimmunol.org)
- Cockroach allergens also may increase a child's risk of developing asthma [IOM 2000, Etzel 2003]. (cdc.gov)
- Cockroach allergens contribute to asthma morbidity, and avoidance strategies can lead to clinical benefit. (dovepress.com)
- immunotherapy with modified allergen extracts. (bioportfolio.com)
- The purpose of this study is to assess the efficacy of two doses of sublingual immunotherapy (SLIT) administered as allergen-based tablets once daily over a period of 12 months compared to. (bioportfolio.com)
- The objective of this clinical trial is to assess the safety and efficacy of sublingual application of allergen extracts for specific immunotherapy in patients suffering from perennial all. (bioportfolio.com)
- Allergen-specific subcutaneous immunotherapy (SCIT) has been shown to be clinically beneficial in many clinical trials. (bioportfolio.com)
- Specific Immunotherapy in LAR: a randomized, double-blind placebo controlled trial with Phleum pratense subcutaneous allergen immunotherapy. (bioportfolio.com)
- Immunotherapy is a method of treating allergies by desensitizing individuals to allergens over time, in many cases with the goal that they be cured of their allergies. (bmc.org)
- The pharmaceutical manufacturer Merck collaborated with Danish company ALK to develop an immunotherapy tablet for house dust mite-induced allergic rhinitis. (nationaleczema.org)
- Allergen avoidance is accomplished through environmental control aimed at reducing exposure to potential allergens. (aafp.org)
- Occupational exposures include work-exacerbated asthma and work-related asthma. (dovepress.com)
- Equally widespread is what is called "occupational asthma," which stems from long-term exposure to hazardous work environments. (seattlepi.com)
- The apparent protection tied to living close to a farm was strongest for those who lived near pig or cattle farms, as well as those who grew up on a farm, the study team reports in Occupational and Environmental Medicine. (reuters.com)
- bit.ly/2K9faym Occupational and Environmental Medicine, online April 30, 2018. (reuters.com)
- If your immune system is oversensitive, it will react to allergens by producing antibodies to fight them off. (naturalcures.com)
- This is the most common type of dermatitis in dogs and cats, occurring when exposure to an environmental allergen results in an inflammatory response (the over-production of antibodies by the immune system) that affects the skin. (bowwowinsurance.com.au)
- Allergic rhinitis (AR) is defined as a symptomatic disease of the nose, resulting from the inflammatory reaction mediated by specific IgE antibodies, and is manifested after the exposure of the mucosa of the nasal cavity to the allergen involved. (scielo.br)
- Serum IgE antibodies to inhalation allergens were found in 80 % of the children. (diva-portal.org)
- For many allergens, such as the house dust mite, the higher the level of exposure, the higher the likelihood of a person producing "allergic" antibodies (called immunglobulin E or IgE antibodies). (vidyya.com)
- The researchers measured the levels of antibodies to cat allergen in 226 children, aged 12 to 14 years, and tested the children for asthma. (vidyya.com)
- The high levels of cat allergen prompted the children's immune systems to predominantly make immunoglobulin G (IgG) and IgG4 antibodies rather than IgE, explains Marshall Plaut, M.D., chief of the allergic mechanisms section at NIAID. (vidyya.com)
- Further investigation into eosinophilic laryngitis as a distinct clinical entity caused by exposure to environmental allergen and pollution is warranted. (sigmaaldrich.com)
- The Health Impacts of Exposure to Indoor Air Pollution from Solid Fuels in Developing Countries: Knowledge, Gaps, and Data Needs. (ebscohost.com)
- Indoor air pollution and childhood asthma: Effective environmental interventions. (ebscohost.com)
- Environmental factors such as pollution, sulfur dioxide, nitrogen oxide, ozone, cold temperatures, and high humidity are all known to trigger asthma in susceptible individuals. (webmd.com)
- Air pollution also might act synergistically with other environmental factors to worsen asthma. (news-medical.net)
- In the modern era, burning fossil fuels, electric power generation, home heating, and motor vehicle transport has greatly increased emissions and pollution exposure. (renalandurologynews.com)
- Definitions of concentration, exposure, and dose are fundamental to considering the effects of air pollution. (renalandurologynews.com)
- 3 One explanation for this rise may be exposure to outdoor 4 and indoor pollution and/or allergens. (bmj.com)
- Environmental influences weigh heavily on early lung growth, particularly traffic-related pollution. (medica-tradefair.com)
- The key driving forces for the nebulizers, inhalers and respirators for asthma treatment market in developing countries are: A large pool of patients, increasing disposable income, higher environmental pollution, a rise in the number of smokers, increasing healthcare awareness, expansion of the aging population base, increasing healthcare expenditure, and improving healthcare infrastructure in the region. (persistencemarketresearch.com)
- More than 11 groups of Dermatophagoides ALLERGENS have been defined. (bioportfolio.com)
- Between two and four repeated measurements of Derp 1, a major allergen of Dermatophagoides pteronyssinus and Der f 1,a major allergen of D. (ebscohost.com)
- In the light of this finding, we have compared pillows with synthetic and feather fillings for their content of Der p I, the major allergen of the house dust mite Dermatophagoides pteronyssinus. (bmj.com)
- Sophisticated mouse models of asthma that utilize clinically relevant allergens such as house dust mite, fungi, and cockroach antigens can be used to study the effects that potential therapeutics have on immunomodulation during disease [ 3 ]. (hindawi.com)
- There is a dose-response relation between exposure to mite antigens and asthma, and a plausible but unproven case can be made for increasing levels of mite in modern heated homes ( 1 ). (sciencemag.org)
- The role of 'autoallergic' phenomena in atopic dermatitis, because of human antigens without known cross-reactivity to environmental allergens, is currently under investigation as well. (ovid.com)
Repeated house dust1
- The variability of repeated house dust mite (HDM) allergen determinations at the same site within 3-24 months was evaluated on previouslycollected samples. (ebscohost.com)
- Before implementing allergen avoidance measures, it first helps to determine which of these allergens a home's occupants are allergic to and whether there is significant exposure to them in the home. (worldallergy.org)
- Allergen avoidance measures were instituted from birth in the prophylactic group (n=58). (bmj.com)
- If there are indeed two (or more) subtypes of asthma, and if non-eosinophilic (neutrophil mediated) asthma is relatively common, this would have major consequences for the treatment and prevention of asthma since most treatment and prevention strategies are now almost entirely focused on allergic/eosinophilic asthma and allergen avoidance measures, respectively. (bmj.com)
Levels of cockroach1
- Boston (21.5%), St Louis (16.3%), and Baltimore (13.4%) had the highest percentages of homes with detectable levels of cockroach allergen. (unboundmedicine.com)
- This study supports the possibility that host-environment interactions that govern allergic or infectious airway disease may be mediated, at least in part, by the impact of environmental exposures on the gastrointestinal microbiome composition and, by extension, its impact on the host immune response. (pnas.org)
- diet and obesity.Environmental exposures in early life that affect immune maturation is the key factor. (indmedica.com)
- In cases of allergic rhinitis, the immune system reacts to an allergen as if it were harmful. (naturalcures.com)
- The involvement of the immune system in the pathogenesis of asthma is complicated and factors such as gender, age, and allergens can alter these responses. (hindawi.com)
- 2. This exposure causes an immune system response in the body, which includes the production of a cascade of immune factors and inflammatory agents. (whole-dog-journal.com)
- When the dog is exposed again to the same allergen, the immunological reaction is amplified and now involves both immune cells and the nervous system. (whole-dog-journal.com)
- When an allergen re-enters the body, the immune system rapidly recognizes it, causing a series of reactions. (bmc.org)
- The study shows that high levels of cat allergen in the home decrease the risk of asthma, apparently by altering the immune response to cats. (vidyya.com)
- It is characterised by an overactive immune response to environmental factors. (dermnetnz.org)
- The immune system's job is to defend your body against things that it sees as foreign and harmful-for example, bacteria, viruses, dust, chemicals. (news-medical.net)
- Smit said the researchers are continuing to explore whether the rich diversity of microbes carried on wind-borne dust from farms might play a role in modulating the immune responses of non-farming neighbors. (reuters.com)
- In this review, clinical and in-vitro data so far published on allergen-induced adaptive immune responses in atopic dermatitis are summarized. (ovid.com)
- Emerging new data have been published particularly on adaptive immune responses to inhalant allergens in atopic dermatitis. (ovid.com)
- There are two predominant types that occur in dogs and cats, atopic dermatitis , when exposure to an environmental allergen results in an inflammatory response, and contact dermatitis , in which affected animals experience a reaction to inhaled or contacted environmental allergens. (bowwowinsurance.com.au)
- This benefit is not that surprising because, according to two reports (See here and here ) by an international task force on canine atopic dermatitis, frequent bathing of dogs, with the specific purpose of removing and reducing exposure to allergens, is identified as one of the most important factors in relieving pruritus (itchiness). (whole-dog-journal.com)
- Early-life exposure to dogs is protective against allergic disease development, and dog ownership is associated with a distinct milieu of house dust microbial exposures. (pnas.org)
- Exposure to dogs in early infancy has been shown to reduce the risk of childhood allergic disease development, and dog ownership is associated with a distinct house dust microbial exposure. (pnas.org)
- microbial exposure. (nih.gov)
- The complex interplay between genetic and environmental factors results in a defective skin barrier that is susceptible to allergen and microbial penetration. (gponline.com)
- Indoor and outdoor dust samples harboured distinct microbial communities, but these differences were larger for bacteria than for fungi with most indoor fungi originating outside the home. (royalsocietypublishing.org)
- More generally, it has been argued that childhood exposure to reduced levels of microbial diversity in and around homes may partially explain the rise in the incidence of allergies and autoimmune disorders in many developed countries [ 13 , 15 ]. (royalsocietypublishing.org)
- Together, our results reveal a novel genetic protective factor (TLR5 deficiency) and a novel environmental pollutant (microbial flagellin) that influence asthma severity. (nih.gov)
- Some kinds of early life exposures, such as having older siblings, attending daycare, exposure to animals and being breastfed, have been reported to be protective, perhaps secondary to microbial factors and immunity [ 14 - 16 ]. (pubmedcentralcanada.ca)
- 7,8 This theory is referred to as the "hygiene hypothesis" and suggests that early exposures to microbial sources, living in large families, less frequent use of antibiotics, and country living stimulate the T H 1 response and thus have a protective effect. (contemporarypediatrics.com)
- Workplace exposures to insects causing allergic disease has occurred where the insects are part of the production process (fish bait manufacturing, labs or facilities raising insects for pest control) or where insect infestations have occurred in workplaces (flour and grain handing facilities including bakeries or farms, hydroelectric dams or mushroom growing facilities). (cdc.gov)
- Nevertheless, advances in molecular biology have led to a better understanding of these allergens and their relationship to allergic disease (21). (phadia.com)
- If you're growing up in an environment devoid of all exposures to animals and allergens, your risk of developing allergic disease tends to be higher," said Dr. Alexander Adami of the University of Connecticut School of Medicine in Farmington, who wasn't involved in the study. (reuters.com)
- Childhood exposure to environmental particulates increases the risk of development of asthma. (biologists.org)
- Despite the conductance of different studies regarding the potential role of allergen avoidance for the primary prevention of childhood asthma, it does not seem that this approach is of benefit for primary prevention purposes. (frontiersin.org)
- To study the Relation-ship between environmental factors and childhood asthma in a rural area has been studied. (indmedica.com)
- To develop a national strategy to prevent childhood asthma, it is critical to estimate the contribution of specific risk factors and the overall contribution of residential exposures to asthma. (aappublications.org)
- The objective of this study was to assess the correlation between childhood asthma and potential risk factors, especially exposure to indoor allergens, in a Native American population. (pubmedcentralcanada.ca)
- Taken together, these studies make a strong argument for the importance of allergen and irritant exposure as aggravating factors in asthma in both children and adults. (cdc.gov)
- This review also covers conditions that may aggravate asthma ( e.g. allergic rhinitis, environmental irritant exposure and obesity) or that may become apparent during follow-up. (ersjournals.com)
- Home intervention of MIECs that comprise diagnostic of allergen/irritant exposure (after sampling), advices for allergen/irritant avoidance and follow up of advice compliance. (clinicaltrials.gov)
- 6 Numerous interventions have been designed to reduce exposure to allergens in the environment where asthma patients live, work, learn, play, and sleep. (ahrq.gov)
- It may involve having to completely prevent access to certain places or the use of funky bodysuits to reduce exposure! (aaps.org.au)
- Riding areas and the dust they generate should be situated away from stalls to reduce exposure to dust. (merckvetmanual.com)
- Kentucky blue grass ( Poa pratensis ), orchard grass ( Dactylis glomerata ), Bermuda grass ( Cynodon dactylon ), and others ( 7 ), are also among the most clinically relevant sources of allergens. (jimmunol.org)
- Work-related allergies and asthma from exposure to insects. (cdc.gov)
- Once it is determined that a person with asthma or rhinitis has allergies, it is next helpful to determine whether there is significant exposure to the relevant allergen(s). (worldallergy.org)
- Several studies support the importance of allergies and allergens in triggering and exacerbating asthma. (cdc.gov)
- Intradermal or serologic testing, as is done with environmental allergies, have been shown to be very inaccurate in diagnosing food allergies. (animalhealthfoundation.net)
- You may think animal allergies are caused by fur, but that fuzz and fluff is merely a carrier for allergens. (nih.gov)
- Although allergen levels can differ among breeds, 2 all breeds, even hairless dogs, can trigger allergies. (nih.gov)
- She also suffers from what we now recognize as seasonal and environmental allergies. (asthmaallergieschildren.com)
- So, without further ado, we bring you five environmental allergies (and how to manage them) with help from Dr. Michael Wein, an allergist-immunologist in Port Saint Lucie, Florida, who is a professor at Florida State University College of Medicine and is affiliated with multiple hospitals in the area. (nationaleczema.org)
- We conclude that injury to airway epithelium by ambient environmental particulates in early life is capable of promoting the development of an asthmatic inflammatory response in sensitized and antigen-challenged mice. (biologists.org)
- When infiltrated into the lung after allergen challenge, eosinophils induce various inflammatory changes in the airways via release of a wide variety of immunomodulator molecules ( 6 , 10 ) including major basic protein ( 11 ). (jimmunol.org)
- Our hypothesis was that release of pro inflammatory interleukins (IL)-6 and IL-8 from primary BAEC cultured from children will be increased after in vitro exposure to common environmental factors. (mdpi.com)
- BAEC from children are able to recognise and respond in vitro with enhanced pro inflammatory mediator secretion to some inhaled exposures. (mdpi.com)
- By identifying the allergens that trigger these inflammatory responses in your body, you're one step closer to getting your AD under control. (nationaleczema.org)
Particularly house dust1
- 9, 10 There is evidence linking exposure to aeroallergens in infancy, particularly house dust mite, with the development of asthma later in life. (bmj.com)
Source of allergens1
- For asthmatics, the most important source of allergens is the house dust mite. (sciencemag.org)
- Children are exposed to many environmental agents that could trigger asthma attacks. (news-medical.net)
- In New Zealand 81% of patients with severe asthma have a positive skin prick test to house dust mite allergen, 3 and exposure to mite allergen is a factor in triggering attacks of asthma in asthmatic subjects. (bmj.com)
- Above a certain cutoff point, children with higher levels of mite allergen exposure had increased rates of nighttime wheezing, daytime cough, and daytime asthma attacks. (health.am)
- The cause of asthma is still uncertain, but environmental factors may play an important role in triggering asthma attacks. (health.am)
- Exposure to allergens such as house dust mite, pets, or dietary products can precipitate attacks of asthma in a sensitised individual. (hstalks.com)
- These findings suggest that concomitant exposure to high levels of certain allergens and bacteria in early life might be beneficial and suggest new preventive strategies for wheezing and allergic diseases. (nih.gov)
- In particular, the female : male ratio and whether a house had pets had a significant influence on the types of bacteria found inside our homes highlighting that who you live with determines what bacteria are found inside your home. (royalsocietypublishing.org)
- Likewise, there is evidence that the types of bacteria and fungi found inside homes can be affected by differences in ventilation, building design, the environmental characteristics found within buildings [ 20 , 22 , 24 - 28 ] or prior water damage from flooding [ 29 ]. (royalsocietypublishing.org)
Amount of allergen2
- Although persistent cough/phlegm was significantly related to mould/dampness exposure in children, regardless of exposure timing, no significant association between mould/dampness exposure and eczema or cough/phlegm was found among adolescents. (bmj.com)
- Recombinant mould allergens of suitable purity and consistency can be produced. (phadia.com)