Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Seminoma: A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)Neoplasms, Germ Cell and Embryonal: Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS.Dysgerminoma: A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Germinoma: A malignant neoplasm of the germinal tissue of the GONADS; MEDIASTINUM; or pineal region. Germinomas are uniform in appearance, consisting of large, round cells with vesicular nuclei and clear or finely granular eosinophilic-staining cytoplasm. (Stedman, 265th ed; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1642-3)Cryptorchidism: A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Breast Neoplasms: Tumors or cancer of the human BREAST.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Disease-Free Survival: Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Survival: Continuance of life or existence especially under adverse conditions; includes methods and philosophy of survival.SEER Program: A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From National Cancer Institute, NIH Publication No. 91-3074, October 1990)Orchiectomy: The surgical removal of one or both testicles.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Bleomycin: A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Survivors: Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Proportional Hazards Models: Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.Cisplatin: An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.Lung Neoplasms: Tumors or cancer of the LUNG.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Testicular Diseases: Pathological processes of the TESTIS.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Early Detection of Cancer: Methods to identify and characterize cancer in the early stages of disease and predict tumor behavior.Neoplasm Recurrence, Local: The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.Retroperitoneal Space: An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.Etoposide: A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.Prostatic Neoplasms: Tumors or cancer of the PROSTATE.SwedenOvarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Neoplasms, Second Primary: Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.United StatesLithiasis: A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Risk: The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.Chemotherapy, Adjuvant: Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.Stomach Neoplasms: Tumors or cancer of the STOMACH.Teratoma: A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)European Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Europe.Infertility, Male: The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Graft Survival: The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.Lymph Node Excision: Surgical excision of one or more lymph nodes. Its most common use is in cancer surgery. (From Dorland, 28th ed, p966)Neoplasm Invasiveness: Ability of neoplasms to infiltrate and actively destroy surrounding tissue.Colonic Neoplasms: Tumors or cancer of the COLON.ScandinaviaOdds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.EuropePhilippinesRadiotherapy: The use of IONIZING RADIATION to treat malignant NEOPLASMS and some benign conditions.NorwaySelf-Examination: The inspection of one's own body, usually for signs of disease (e.g., BREAST SELF-EXAMINATION, testicular self-examination).Single-Payer System: An approach to health care financing with only one source of money for paying health care providers. The scope may be national (the Canadian System), state-wide, or community-based. The payer may be a governmental unit or other entity such as an insurance company. The proposed advantages include administrative simplicity for patients and providers, and resulting significant savings in overhead costs. (From Slee and Slee, Health Care Reform Terms, 1993, p106)DenmarkGene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Health Status Disparities: Variation in rates of disease occurrence and disabilities between population groups defined by socioeconomic characteristics such as age, ethnicity, economic resources, or gender and populations identified geographically or similar measures.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Carcinoma, Non-Small-Cell Lung: A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.Vinblastine: Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Confidence Intervals: A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.Age Distribution: The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Twinning, Monozygotic: The division of a ZYGOTE into two parts, each of which is capable of further development.Lymphatic Metastasis: Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.JapanPancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Radiotherapy, Adjuvant: Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Retroperitoneal NeoplasmsCell Line, Tumor: A cell line derived from cultured tumor cells.EnglandNeoplasm Grading: Methods which attempt to express in replicable terms the level of CELL DIFFERENTIATION in neoplasms as increasing ANAPLASIA correlates with the aggressiveness of the neoplasm.African Americans: Persons living in the United States having origins in any of the black groups of Africa.Rectal Neoplasms: Tumors or cancer of the RECTUM.WalesLiver Neoplasms: Tumors or cancer of the LIVER.Carcinoma, Embryonal: A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595)Receptors, Estrogen: Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).Chorionic Gonadotropin: A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Chromomycin A3: Glycosidic antibiotic from Streptomyces griseus used as a fluorescent stain of DNA and as an antineoplastic agent.Testis: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.Uterine Cervical Neoplasms: Tumors or cancer of the UTERINE CERVIX.Chorionic Gonadotropin, beta Subunit, Human: The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.alpha-Fetoproteins: The first alpha-globulins to appear in mammalian sera during FETAL DEVELOPMENT and the dominant serum proteins in early embryonic life.Life Tables: Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.GermanySocial Class: A stratum of people with similar position and prestige; includes social stratification. Social class is measured by criteria such as education, occupation, and income.Drug Resistance, Neoplasm: Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Gonadal Dysgenesis: A number of syndromes with defective gonadal developments such as streak GONADS and dysgenetic testes or ovaries. The spectrum of gonadal and sexual abnormalities is reflected in their varied sex chromosome (SEX CHROMOSOMES) constitution as shown by the karyotypes of 45,X monosomy (TURNER SYNDROME); 46,XX (GONADAL DYSGENESIS, 46XX); 46,XY (GONADAL DYSGENESIS, 46,XY); and sex chromosome MOSAICISM; (GONADAL DYSGENESIS, MIXED). Their phenotypes range from female, through ambiguous, to male. This concept includes gonadal agenesis.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Sexual Dysfunction, Physiological: Physiological disturbances in normal sexual performance in either the male or the female.Ontario: A province of Canada lying between the provinces of Manitoba and Quebec. Its capital is Toronto. It takes its name from Lake Ontario which is said to represent the Iroquois oniatariio, beautiful lake. (From Webster's New Geographical Dictionary, 1988, p892 & Room, Brewer's Dictionary of Names, 1992, p391)Healthcare Disparities: Differences in access to or availability of medical facilities and services.Sperm Banks: Centers for acquiring and storing semen.Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.Mice, Nude: Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Carcinoma in Situ: A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.Sperm Count: A count of SPERM in the ejaculum, expressed as number per milliliter.China: A country spanning from central Asia to the Pacific Ocean.Fertility: The capacity to conceive or to induce conception. It may refer to either the male or female.Hawaii: A group of islands in Polynesia, in the north central Pacific Ocean, comprising eight major and 114 minor islands, largely volcanic and coral. Its capital is Honolulu. It was first reached by Polynesians about 500 A.D. It was discovered and named the Sandwich Islands in 1778 by Captain Cook. The islands were united under the rule of King Kamehameha 1795-1819 and requested annexation to the United States in 1893 when a provisional government was set up. Hawaii was established as a territory in 1900 and admitted as a state in 1959. The name is from the Polynesian Owhyhii, place of the gods, with reference to the two volcanoes Mauna Kea and Mauna Loa, regarded as the abode of the gods. (From Webster's New Geographical Dictionary, 1988, p493 & Room, Brewer's Dictionary of Names, 1992, p2330)Infant, Newborn: An infant during the first month after birth.Great BritainMedical Oncology: A subspecialty of internal medicine concerned with the study of neoplasms.Chlordan: A highly poisonous organochlorine insecticide. The EPA has cancelled registrations of pesticides containing this compound with the exception of its use through subsurface ground insertion for termite control and the dipping of roots or tops of non-food plants. (From Merck Index, 11th ed)Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.Neoplasms, Radiation-Induced: Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation.Neoplasm Proteins: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.CaliforniaLogistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Lactate Dehydrogenases: Alcohol oxidoreductases with substrate specificity for LACTIC ACID.Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.Receptors, Progesterone: Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Cancer Vaccines: Vaccines or candidate vaccines designed to prevent or treat cancer. Vaccines are produced using the patient's own whole tumor cells as the source of antigens, or using tumor-specific antigens, often recombinantly produced.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Carboplatin: An organoplatinum compound that possesses antineoplastic activity.Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.Paresthesia: Subjective cutaneous sensations (e.g., cold, warmth, tingling, pressure, etc.) that are experienced spontaneously in the absence of stimulation.Tissue Array Analysis: The simultaneous analysis of multiple samples of TISSUES or CELLS from BIOPSY or in vitro culture that have been arranged in an array format on slides or microchips.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Recurrence: The return of a sign, symptom, or disease after a remission.Antineoplastic Agents, Hormonal: Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)Genital Diseases, Male: Pathological processes involving the male reproductive tract (GENITALIA, MALE).Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Mammography: Radiographic examination of the breast.Neoplasms, Connective Tissue: Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue.Asian Americans: Persons living in the United States having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.Masculinity: Male-associated sex-specific social roles and behaviors unrelated to biologic function.African Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Africa.New MexicoSex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Ethnic Groups: A group of people with a common cultural heritage that sets them apart from others in a variety of social relationships.Spermatozoa: Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.Polymorphism, Genetic: The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Perinatology: The branch of medicine dealing with the fetus and infant during the perinatal period. The perinatal period begins with the twenty-eighth week of gestation and ends twenty-eight days after birth. (From Dorland, 27th ed)Spermatogenesis: The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Models, Statistical: Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.Testicular Hydrocele: Accumulation of serous fluid between the layers of membrane (tunica vaginalis) covering the TESTIS in the SCROTUM.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Salvage Therapy: A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.Fluoroimmunoassay: The use of fluorescence spectrometry to obtain quantitative results for the FLUORESCENT ANTIBODY TECHNIQUE. One advantage over the other methods (e.g., radioimmunoassay) is its extreme sensitivity, with a detection limit on the order of tenths of microgram/liter.Urogenital Neoplasms: Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.Orchiopexy: A surgical procedure in which an undescended testicle is sutured inside the SCROTUM in male infants or children to correct CRYPTORCHIDISM. Orchiopexy is also performed to treat TESTICULAR TORSION in adults and adolescents.Confounding Factors (Epidemiology): Factors that can cause or prevent the outcome of interest, are not intermediate variables, and are not associated with the factor(s) under investigation. They give rise to situations in which the effects of two processes are not separated, or the contribution of causal factors cannot be separated, or the measure of the effect of exposure or risk is distorted because of its association with other factors influencing the outcome of the study.Vasectomy: Surgical removal of the ductus deferens, or a portion of it. It is done in association with prostatectomy, or to induce infertility. (Dorland, 28th ed)Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Birth Order: The sequence in which children are born into the family.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Semen: The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.Ifosfamide: Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.Continental Population Groups: Groups of individuals whose putative ancestry is from native continental populations based on similarities in physical appearance.Actuarial Analysis: The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.Xenograft Model Antitumor Assays: In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Scrotum: A cutaneous pouch of skin containing the testicles and spermatic cords.Watchful Waiting: Clinical management approach wherein immediate therapy is not provided but there is a period of observation during which periodic tests monitor patient and the progression of the illness. (Driffield T, Smith PC Med Decis Making. 2007 Mar-Apr;27(2):178-88)Receptor, erbB-2: A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.Genital Neoplasms, Male: Tumor or cancer of the MALE GENITALIA.Research Design: A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.Platinum Compounds: Inorganic compounds which contain platinum as the central atom.Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)Polymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.
Cancer survival rates
Several types of cancer are associated with high survival rates, including breast, prostate, testicular and colon cancer. Brain ... Indeed, pancreatic cancer has one of the worst survival rates of all cancers. The five-year survival rate for breast cancer is ... "Breast Cancer Survival Rates & Statistics". www.cancer.org. Retrieved 2017-04-21. Cancer survival figures issued by the Office ... breast cancer. In cancer types with high survival rates, incidence is usually higher in the developed world, where longevity is ...
Five-year survival rate rates in the United States is about 95%. Outcomes are better when the disease remains localized. One of ... Higher rates of testicular cancer in Western nations have been linked to the use of cannabis. Most testicular germ cell tumors ... "Testicular Cancer Survival Rates". www.cancer.org. Retrieved 2018-01-18. "Testicular Cancer survival statistics". ... Globally testicular cancer resulted in 8,300 deaths in 2013 up from 7,000 deaths in 1990. Testicular cancer has the highest ...
"Symptoms of kidney cancer". Katie Charles (January 19, 2011). "Kidney cancer: Innovative new treatments boost survival rates ... of all cancers. The highest rates are recorded in North America and the lowest rates in Asia and Africa. The United States' NIH ... Overall five year survival rate in the United States is 73%. For cancers that are confined to the kidney, the five year ... and previous treatment for testicular cancer or cervical cancer. There are also other possible risk factors such as kidney ...
... lung cancer, and medulloblastoma. In completely resected medulloblastoma, 5-year survival rate is 85% if adjuvant chemotherapy ... Multiple studies have shown that adjuvant radiotherapy improves local recurrence rates in high-risk melanoma patients. The ... In testicular cancer, adjuvant either radiotherapy or chemotherapy may be used following orchidectomy. Previously, mainly ... lung cancer, pancreatic cancer, breast cancer, prostate cancer, and some gynaecological cancers. Some forms of cancer fail to ...
The overall 5-year survival rate for all stages of penile cancer is about 50%. Penile cancer is a rare cancer in developed ... www.cdc.gov/cancer/hpv/statistics/penile.htm HPV-Associated Penile Cancer Rates by Race and Ethnicity] Center for Disease ... Penile cancer arises from precursor lesions, which generally progress from low-grade to high-grade lesions. For HPV related ... de Souza KW, dos Reis PE, Gomes IP, de Carvalho EC (March 2011). "[Prevention strategies for testicular and penile cancer: an ...
... of all cancers. The highest rates are recorded in North America and the lowest rates in Asia and Africa. ... For cancers that are confined to the kidney, the five-year survival rate is 93%, if it has spread to the surrounding lymph ... and previous treatment for testicular cancer or cervical cancer. There are also other possible risk factors such as kidney ... "National Cancer Institute. 2019. Retrieved 8 June 2019.. *^ a b c d e f g h "Cancer of the Kidney and Renal Pelvis - Cancer ...
Acute lymphoblastic leukemia
Survival for children increased from under 10% in the 1960s to 90% in 2015. Survival rates remain lower for babies (50%) and ... This result is questioned as no causal mechanism linking electromagnetic radiation with cancer is known. High birth weight ( ... Pediatric patients with ALL in developed countries have a greater than 80% five-year-survival rate. It is estimated that 60-80 ... which are tiny red spots or lines in the skin due to low platelet levels Testicular enlargement Mediastinal mass The cancerous ...
... obese people have higher levels of some hormones associated with cancer and a higher rate of those cancers. Women who take ... Survival rates vary by cancer type and by the stage at which it is diagnosed, ranging from majority survival to complete ... testicular cancer, ovarian cancer, pancreatic cancer, or prostate cancer. Recommends mammography for breast cancer screening ... colorectal cancer, pancreatic cancer, osteogenic sarcoma, testicular cancer, ovarian cancer and certain lung cancers. ...
Randomized controlled trial
One example is combination chemotherapy including cisplatin for metastatic testicular cancer, which increased the cure rate ... a rating of "I-good") as the highest quality evidence available to it. The GRADE Working Group concluded in 2008 that " ... For time-to-event outcome data that may be censored, survival analysis (e.g., Kaplan-Meier estimators and Cox proportional ... Einhorn LH (2002). "Curing metastatic testicular cancer". Proc Natl Acad Sci U S A. 99 (7): 4592-5. doi:10.1073/pnas.072067999 ...
... or live birth rate, whether from IVF or oocyte donation cycles. Rather, oocyte age, survival proportion, and number of ... as clinical pregnancy rate is four times higher after oocyte vitrification than after slow freezing. Oocyte vitrification is ... or whose reproductive potential is threatened by cancer therapy, for example in hematologic malignancies or breast cancer. The ... Cryopreservation of immature testicular tissue is a developing method to avail reproduction to young boys who need to have ...
Acute lymphoblastic leukemia
These people in relapse may also receive blinatumomab, as it has shown to increase remission rates and overall survival rates, ... "National Cancer Institute. 8 December 2017. Retrieved 20 December 2017.. *^ a b c d e f g h i j k l m n o p q r s Hunger SP, ... Children: 90% five-year survival rate. Adults: 35% five-year survival. ... High birth weight (greater than 4000g or 8.8lbs) is also associated with a small increased risk. The mechanism connecting high ...
Epidemiology of cancer
Some types of cancer, like testicular cancer, have early-life incidence peaks, for reasons unknown. Besides, the rate of age- ... White infants have higher cancer rates than black infants. Leukemias accounted for a substantial proportion of this difference ... 1999). Cancer Incidence and Survival among Children and Adolescents, United States SEER program 1975-1995. Bethesda MD: ... which causes cervical cancer and some forms of anal cancer, vaginal cancer, vulvar cancer, penile cancer, rectal cancer, and ...
One exception is testicular germ cell cancer which occurs at a higher rate in DS. ... Higher rates of tooth wear and bruxism are also common. Other common oral manifestations of Down syndrome include enlarged ... The probability of long-term survival is partly determined by the presence of heart problems. In those with congenital heart ... Cancer. Although the overall risk of cancer in DS is not changed, the risk of testicular cancer and certain blood cancers, ...
... the risk of leukemia and testicular cancer is increased and risk of solid cancers is reduced. Solid cancers are believed to be ... In the United States, termination rates are around 67%, but this rate varied from 61% to 93% among different populations. Rates ... less effective oral hygiene habits and higher plaque indexes. Higher rates of tooth wear and bruxism are also common. Other ... The probability of long-term survival is partly determined by the presence of heart problems. In those with congenital heart ...
... and the five-year survival rate is now around 80%. The survival rate depends largely on the severity of disease and other ... "E-medicine liver transplant outlook and survival rates". Emedicinehealth.com. 2009-06-09. Archived from the original on 2009-07 ... Non-alcoholic fatty liver disease has a number of causes, including being overweight, diabetes, high blood fats, and high blood ... Hypogonadism, a decrease in male sex hormones may manifest as impotence, infertility, loss of sexual drive, and testicular ...
Intracytoplasmic sperm injection
... a novel approach to obtain higher oocyte survival and embryo quality rates" (PDF). Human Reproduction. 17 (10): 2694-2699. doi: ... Live birth rate are significantly higher with progesterone to assist implantation in ICSI cycles. Also, addition of a GNRH ... It can also be used in Azoospermia, "Valious spermatozoa" (from Fertility Preservation after cancer, or because of a ... In cases of nonobstructive (secretory) azoospermia, on the other hand, testicular sperm production is blocked at different ...
See also: Cancer survival rates, List of cancer mortality rates in the United States, and Cancer survivor ... obese people have higher levels of some hormones associated with cancer and a higher rate of those cancers. Women who take ... colorectal cancer, pancreatic cancer, osteogenic sarcoma, testicular cancer, ovarian cancer and certain lung cancers. ... lung cancer, lymphoma, pancreatic cancer, prostate cancer, skin cancer, and thyroid cancer as well as other cancer types. ...
Soloway MS: The use of an animal model to gain insights into bladder cancer therapy. In: Testicular Cancer and Other Tumors of ... he was also testing the hypothesis that the high rate of local recurrence of urothelial tumors may be the result of ... Prostate specific antigen recurrence rates are low after radical retropubic prostatectomy and positive margins. J Urol, 175(1): ... there was no improvement in progression free or overall survival. Other groups who later performed similar studies have ...
Science and technology in Israel
Israeli publications have a high citation rate and a high share of papers count among the 10% most-cited. The share of papers ... Food and Drug Administration and is already being used in diagnosing breast and testicular cancer. The new system will replace ... It also has one of the highest per capita rates of filed patents. Israel counts 140 scientists and technicians per 10,000 ... irrigation and water engineering is vital to the country's economic survival and growth. Large-scale projects to direct water ...
Kanser, ang malayang ensiklopedya
Ang mga taong mahina at may iba pang mga problema sa kalusugan ay may maliit na rate ng survival kesa sa mga malusog na tao. ... "How much of the decrease in cancer death rates in the United States is attributable to reductions in tobacco smoking?". Tob ... High-risk progressive or recurrent lymphomas m-BACOD Methotrexate, bleomycin, Adriamycin (doxorubicin), cyclophosphamide, ... Gastric cancer and oesophageal cancer EP Etoposide, platinum agent (cisplatin (Platinol)) Testicular cancer, germ cell tumors ...
... because castrated males cannot develop testicular cancer, spayed females cannot develop uterine or ovarian cancer, and both ... Cats have a high breeding rate. Under controlled breeding, they can be bred and shown as registered pedigree pets, a hobby ... Despite some cats cohabiting in colonies, they do not have a social survival strategy, or a pack mentality, and always hunt ... in addition to lower reproductive rates and extended incubation periods. The loss of flight, or reduced flying ability is also ...
Paternal care increases offspring survival due to increased access to higher quality food and reduced physical and ... testosterone increases beyond the castrate level have been shown to increase the rate of spread of an existing prostate cancer. ... A testicular action was linked to circulating blood fractions - now understood to be a family of androgenic hormones - in the ... Southren AL, Tochimoto S, Carmody NC, Isurugi K (Nov 1965). "Plasma production rates of testosterone in normal adult men and ...
Sperm count decline and increasing rate of testicular cancers in the West may be linked to a higher presence of isoflavone ... Shu XO, Zheng Y, Cai H, Gu K, Chen Z, Zheng W, Lu W (Dec 2009). "Soy food intake and breast cancer survival". JAMA. 302 (22): ... and that it may decrease mortality and recurrence rates. It remains unclear if phytoestrogens can minimize some of the ... Flax seed and other oilseeds contained the highest total phytoestrogen content, followed by soybeans and tofu. The highest ...
The rate of occurrence is highest in peoples of Western European descent, averaging around 7 per 100,000 people, and is lower ... It occurred at higher rates within personal relationships than health insurance or employment relations. Genetic counseling in ... If the expression of HTT is increased and more HTT produced, brain cell survival is improved and the effects of mHTT are ... and testicular atrophy. All humans have two copies of the Huntingtin gene (HTT), which codes for the protein Huntingtin (HTT). ...
April 2014). "Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer". ... have lower rates of cancer. Male smokers have between 1.5 and 2 times the risk of non-respiratory cancers as female smokers. ... high mutation rate, inefficient selection, and genetic drift. However, comparisons of the human and chimpanzee Y chromosomes ( ... The only well-defined human disease linked to a defect on the Y chromosome is defective testicular development (due to deletion ...
August 1983). "Improved survival among patients treated with adjuvant tamoxifen after mastectomy for early breast cancer". ... in cases where the risk of breast cancer recurrence without the drug is higher than the risk of developing uterine cancer with ... Tamoxifen doses and rates of bicalutamide-induced breast symptoms in men Time. Placebo. 1 mg/day. 2.5 mg/day. 5 mg/day. 10 mg/ ... It has been found to decrease growth velocity and the rate of bone maturation in girls with precocious puberty, and hence to ...
Long-term effects of alcohol consumption
Death rate amongst current drinkers was higher for 'alcohol augmentable' disease such as liver disease and oral cancers, but ... Alcoholics have a higher risk of developing acute respiratory distress syndrome (ARDS) and experience higher rates of mortality ... In men, high levels of estrogen can lead to testicular failure and the development of feminine traits including development of ... and survival." The authors replied that "whether or not the apparent shortfall in breast cancer mortality among heavy drinkers ...
... high-dose; 100 mg/mL, 300 mg/3 mL; brand name Androcur Depot). The high-dose formulations are used to treat prostate cancer and ... A rate of gynecomastia of 7% has been reported. CPA has been associated with an increased rate of depression in both men and ... castration has never been shown in any controlled study to prolong disease-free survival or overall survival in prostate cancer ... Ayub M, Levell MJ (July 1987). "Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens ...
... food sharing generated higher levels of oxytocin. This comparatively higher level of oxytocin after food sharing parallels the ... regulation of heart rate. • response to sucrose. • positive regulation of ossification. • positive regulation of synapse ... The Leydig cells in some species have been shown to possess the biosynthetic machinery to manufacture testicular oxytocin de ... In a study where such a relationship was examined, it was found that when individuals were administered oxytocin, rates of ...
High mutation rateEdit. The human Y chromosome is particularly exposed to high mutation rates due to the environment in which ... "Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer". Nature Genetics ... This usually results in defective testicular development, such that the infant may or may not have fully formed male genitalia ... and perhaps a higher percentage of other cells lacking it) have a higher risk of certain cancers and have a shorter life ...
See also: Cancer survival rates, List of cancer mortality rates in the United States, and Cancer survivor ... obese people have higher levels of some hormones associated with cancer and a higher rate of those cancers. Women who take ... colorectal cancer, pancreatic cancer, osteogenic sarcoma, testicular cancer, ovarian cancer and certain lung cancers. ... lung cancer, lymphoma, pancreatic cancer, prostate cancer, skin cancer, and thyroid cancer as well as other cancer types. ...
Diabetes mellitus type 1
Rates vary widely by country. In Finland, the incidence is a high of 57 per 100,000 per year, in Japan and China a low of 1 to ... Women with type 1 diabetes show a higher than normal rate of polycystic ovarian syndrome (PCOS). The reason may be that the ... and for treating metastatic cancer of the pancreatic islet cells in patients whose cancer cannot be removed by surgery. ... There is no known way to prevent type 1 diabetes. Treatment with insulin is required for survival. Insulin therapy is ...
... factors and high rates of blood clots at the high doses used to achieve castrate levels of testosterone in prostate cancer. ... effects on overall survival and cardiovascular mortality. The Scandinavian Prostatic Cancer Group (SPCG)-5 Trial Study". ... encouraging results of a cheap and effective hormonal therapy with a low rate of side-effects in patients with prostate cancer. ... testicular atrophy, allergic reactions (e.g., urticaria, bronchial asthma, anaphylactic shock) due to mepivacaine, and ...
In a comparative trial of combined androgen blockade for prostate cancer, the rate of diarrhea was 26% for flutamide and 12% ... In the case of antiandrogen monotherapy for prostate cancer, the rates of diarrhea are 5-20% for flutamide, 2-5% for ... However, at high concentrations, unlike flutamide, hydroxyflutamide is able to weakly activate the AR. Flutamide has far lower ... Ayub, M.; Levell, M.J. (1987). "Inhibition of rat testicular 17α-hydroxylase and 17,20-lyase activities by anti-androgens ( ...
April Is Testicular Cancer Awareness Month | Mens Health Network
... it is the most common form of cancer among men between 15 and 35 years old. It has one of the highest survival rates, if found ... "The good news is that testicular cancer, if caught early, has a 99 percent five-year survival rate," said Ana Tomsic, Vice ... "Testicular Cancer is bigger than any one organization, and partnering with like-minded organizations in the testicular cancer ... "Testicular cancer is the most common cancer in young men ages 15 to 35, which means prevention needs to start early," said ...
Testicular Cancer - American Family Physician
Survival rates in patients with testicular cancer have improved dramatically in the past 20 years and now exceed 90 percent ... A painless testicular mass is the classic presentation for testicular cancer, although a number of patients present with ... Cryptorchidism is the most significant risk factor for testicular cancer, increasing the risk up to 11-fold. ... Although testicular cancer accounts for only 1 percent of all tumors in males, it is the most common malignancy in males ...
April Is Testicular Cancer Awareness Month - Self Examination Tips & More
Learn testicular cancer facts, the symptoms, and tips for self-examination. ... Testicular cancer has a high survival rate. And a very high survival rate if you get treated. Finding a lump shouldnt feel ... If youre not satisfied with your newsletter, you can simply cancel your subscription and receive a pro-rated refund on all ... Testicular cancer is treatable, and with early treatment, the survival rate is high. But, like any cancer, if ignored and left ...
The 10 health symptoms men should NEVER ignore as studies show males are still dodging the doctor - Mirror Online
Testicular cancer has a very high survival rate if caught early.. Video Loading Video Unavailable ... Rates of illnesses such as heart disease and common cancers are all higher in men. And they are 37% more likely to die from ... To find out how, visit orchid-cancer.org.uk/testicular-cancer . If youre worried about anything, see your GP. ... However, a lump always needs checking out as it may be a symptom of testicular cancer, which affects 2,300 men a year in the UK ...
Cancer survival rates - Wikipedia
Several types of cancer are associated with high survival rates, including breast, prostate, testicular and colon cancer. Brain ... Indeed, pancreatic cancer has one of the worst survival rates of all cancers. The five-year survival rate for breast cancer is ... "Breast Cancer Survival Rates & Statistics". www.cancer.org. Retrieved 2017-04-21. Cancer survival figures issued by the Office ... breast cancer. In cancer types with high survival rates, incidence is usually higher in the developed world, where longevity is ...
CNN.com - Paging Dr. Gupta Blog
Your friend gets diagnosed with late stage testicular cancer. Testicular cancer has one of the highest survival rates so long ... He would have died to his cancer at an accelerated rate? The cancer would have been less painful? You would have had to cancel ... But three weeks before the ceremony, Hans learned he had testicular cancer. He was 38. The prognosis wasnt good. The cancer ... One study actually showed the people who had been prayed for and knew they were being prayed for had a lower survival rate than ...
Testicular Cancer: Diagnosis and Treatment - American Family Physician
With effective treatment, the overall five-year survival rate is 97%. Risk factors for testicular cancer include undescended ... personal or family history of testicular cancer, age, ethnicity, and infertility. The U.S. Preventive Services Task Force ... Family physicians often play a role in the care of cancer survivors and should be familiar with monitoring for recurrence and ... Testicular cancer is the most common solid tumor among males 15 to 34 years of age, with an estimated 8,850 new cases and 410 ...
Media backgrounder: Canadian Cancer Statistics 2011 - Canadian Cancer Society
Relative survival is highest for thyroid, prostate and testicular cancers, which all have survival rates above 90%. ... Overall incidence rate: Since 1993, there has been a decline in the overall cancer incidence rate in men but the rate has ... Relative survival is lowest for lung, esophagus and pancreas cancers, which all have survival rates of 16% or lower. ... No major increases in death rates for most cancers were observed, although the liver cancer death rate has been increasing 1.8 ...
Top 7 most curable cancers based on 5-year relative survival rate
Here, we look at seven cancers with high survival rates. ... may base the outlook on the 5-year relative survival rate. This ... is the percentage of people likely to survive for 5 years after diagnosis compared to people without cancer. ... There is no cure for cancer, but successful treatment can remove all signs of it. Doctors ... 3. Testicular cancer. The 5-year relative survival rate for testicular cancer is 99 percent for localized tumors, which are ...
'Less Is More' When it Comes to Testicular Cancer Chemo, Study Suggests | Doctors...
Survival rates for testicular cancer are very high, but many patients are diagnosed in their 20s and 30s, so having ... After two years, testicular cancer returned in just 1.3% of the patients. That was nearly identical to the rate found in prior ... In the new study, Huddarts group tracked outcomes for nearly 250 men with early-stage testicular cancer that was at high risk ... Currently, testicular cancer patients first undergo surgical removal of the affected testicle. They then choose between two ...
Alternative Cancer Treatments for Testicular Mesothelioma | New Hope Unlimited
New Hope offers individualized alternative cancer treatment programs for Testicular Mesothelioma to meet each patients needs. ... men with cancer that has not spread beyond the testicles have a high survival rate of 99 percent, according to Cancer.Net. ... 4. What should I know about testicular mesothelioma survival rates?. With the appropriate treatment, ... Alternative Treatments for Testicular Mesothelioma: Personalized Cancer Care That Works. Be a cancer survivor. At New Hope ...
Firefighter Resources, Cancer and Other Illnesses | NIOSH | CDC
Fire launched a multi-year to examine whether firefighters have a higher risk of cancer and other causes of death due to job ... but also at the diagnosis of certain kinds of cancer, such as testicular and prostate cancer, which have higher survival rates ... NIOSH recommends workplace noise levels are below 85 dBA (8-hour time-weighted average of 85 dBA based on a 3-dB exchange rate ... Cancer and Other Illnesses. Cancer. Highlight. National Firefighter Registry: On Monday, July 9th 2018 President Donald Trump ...
Cancer survival rates higher than previously assumed | EurekAlert! Science News
Conventional estimates for life expectancy after cancer diagnosis have been too pessimistic, suggests a study in this weeks ... By period analysis, 20-year relative survival rates were close to 90% for thyroid and testicular cancer, exceeded 80% for ... A 20-year relative survival rate of 65% was estimated for breast cancer, of 60% for cervical cancer, and of about 50% for ... Cancer survival rates higher than previously assumed N.B. Please note that if you are outside North America the embargo date ...
Surveillance vs. adjuvant therapy of clinical stage I testicular tumors - a review and the SWENOTECA experience
... have been to reduce treatment intensity while maintaining high survival rates, reduce the number of patients needing salvage ... testicular cancer is highly curable, the optimal management is controversial. The aims of the Swedish and Norwegian Testicular ... The relapse rate for NS CS I with BEPx1 was 3.2% for high risk, and 1.6% for low-risk patients. Five-year cause-specific ... have been to reduce treatment intensity while maintaining high survival rates, reduce the number of patients needing salvage ...
Cancers With The Lowest Mortality Rates - WorldAtlas
Here is a look at the ten cancers with the lowest known mortality rates in the US. ... Being diagnosed with any form of cancer can be a difficult thing to live through. ... The five-year survival rate for testicular cancer is 95.1%, and at ten years, men face a 94.6% survival rate. ... Skin cancer can come in many forms, and some types have higher recovery rates than others. Melanoma has a five-year survival ...
Marijuana Side Effects, Signs & Symptoms of Abuse
While testicular cancer is treatable and has a high survival rate, experiencing testicular cancer at a younger age can also ... a unique form of testicular cancer that disproportionately affects young men. ... This is because it raises blood pressure and heart rate, but reduces the bloods ability to carry oxygen. A heart attack can be ... As a result, a person may choose to drive a car while impaired or have unprotected sex while high. By impairing ones judgment ...
Intentionally Skewed Cancer Survival Rates | LifeEthics
In five cancers -- breast, prostate, thyroid, testicular and skin melanoma -- American survival rates are higher than 90 ... European women are only 55.8 percent likely to live five years after contracting any kind of cancer, compared to 62.9 percent ... American survival rates are higher than 90 percent. Europeans hit a 90 percent survival rate for only one of those - testicular ... Intentionally Skewed Cancer Survival Rates. Posted by bnuckols ⋅ October 8, 2009. ⋅ Leave a comment ...
No data available that match "higher rates of testicular cancer survival rate"
TesticlesCases of testicular cancerCervicalCurableUndescended testisMelanoma2019TreatableTesticleMortalitySign of testicular cancerSymptom of testicular cancerPrognosisDevelop testicular cancerSymptomsStage 2 testiculThyroid cancerSurvivorsLast 40 yearsOrchiectomyDysgenesis syndromeRecurrenceCryptorchidismScrotumSeminomasLymph nodesCommon cancersTestis cancerTumor-markerTestesIncreasesTreatmentsCancerousOutcomes2018ColorectalMalesLumpBladderUterineSurgeryLymphomasTypesTreatPeople who are diagnosedAwareness MonthSurveillanceSELF-EXAMSpread to other organsRisk factorsYearsRelapse rateRelative survivalYear survivalLeft untreatedWhites
- Another symptom of testicular cancer is that your testicles may hurt. (doctorshealthpress.com)
- In the early stages of testicular cancer, doctors can remove either one or both of the testicles to treat the condition. (medicalnewstoday.com)
- History of cancer in the testicles - if a male had cancer in one testicle, there is an increased likelihood the other testicle will develop cancer. (thomasahleringmd.com)
- Family history of testicular cancer - a man whose brother or father may have had cancer of the testicles has a greater risk of developing it himself. (thomasahleringmd.com)
- Congenital abnormalities - Men with a hernia in the groin area, and those having abnormalities at birth involving the kidneys, testicles or penis are at increased risk to develop testicular cancer. (thomasahleringmd.com)
- Usually, a lump in the testicles is the first sign of testicular cancer. (thomasahleringmd.com)
- A more aggressive type that has a higher risk of spreading beyond the testicles. (first4lawyers.com)
- Testicular cancer is the cancer in the testicles, the male reproductive organ that makes hormones and sperm. (onco.com)
- In stage IB of testicular cancer becomes more complicated when tumor invaded to blood vessels and lymph including the outer layer which covers testicles, scrotum and spermatic cord. (onco.com)
- Stage I of testicular cancer can be diagnosed early and since it has not spread beyond the testicles to the lymph nodes or other organs, in most cases, surgical treatments alone can treat testicular cancers of stage I. The treatment is based on whether the testicular cancer is seminoma or non seminoma, though factors like medical history and tolerance of the patient play a role too. (onco.com)
- Testicular cancer (वृषण कैंसर ) is cancer that develops in the testicles, a part of the male reproductive system . (siddhaspirituality.com)
- However, the American Cancer Society suggests that some men should examine their testicles monthly, especially if they have a family history of cancer. (siddhaspirituality.com)
- Other types of cancer, such as lymphoma and leukemia, occasionally spread to the testicles. (lineagotica.info)
- To find out more about cancer that started in another part of the body and spread to the testicles, read about that specific type of cancer . (lineagotica.info)
- Injuring your testicles ups your chances of getting testicular cancer. (bottomlineinc.com)
- Sophisticated new genetic tests can help identify, for example, the risk that a man born with undescended testicles actually has of developing the cancer. (bottomlineinc.com)
Cases of testicular cancer3
- 1 In 2017, there were an estimated 8,850 new cases of testicular cancer and 410 deaths. (aafp.org)
- With the incidence reported by GLOBOCAN and the results of the 2017 census, we can estimate for the year 2018 an approximate of 817 new cases of testicular cancer . (peertechz.com)
- Even though prostate cancer rates rise with age, especially after age 60, the majority of the approximately 8,850 cases of testicular cancer diagnosed each year in the US are found in men ages 15 to 40. (bottomlineinc.com)
- A 20-year relative survival rate of 65% was estimated for breast cancer, of 60% for cervical cancer, and of about 50% for colorectal, ovarian, and kidney cancer. (eurekalert.org)
- Subgroups of adolescents and young adults that showed worsening trends in survival between the two time periods included black people with bone/soft tissue sarcoma, 20 to 24 year old women with cervical cancer, and poor adolescents and young adults with cervical cancer. (sciencecodex.com)
- Dr Carter added that more people lose their lives to mouth cancer every year in Britain than from cervical and testicular cancer combined. (express.co.uk)
- Cervical cancer is the cancer that originates from the cervix because of the abnormal growth of cells which are capable of spreading to or invading other parts of the body. (healthician.org)
- Cervical cancer incidence is dropping with greater use of screening, which also reduces death from this disease. (usc.edu)
- Vaccination and the HPV vaccine was approved in 2006 and is effective in reducing cervical cancer. (usc.edu)
- It has the worst survival rate of any common cancer and compares with 97%, 85%, and 66% survival for testicular, breast and cervical cancers respectively. (pancreaticcanceraction.org)
- What are the most curable cancers? (medicalnewstoday.com)
- Although clinical stage I (CS I) testicular cancer is highly curable, the optimal management is controversial. (lu.se)
- Testicular cancer is a highly treatable, usually curable, cancer that most often develops in young and middle-aged men. (uwhealth.org)
- Testicular cancer is very curable. (thedogvisitor.com)
- Stage I of testicular cancer is one of the most curable cancer. (onco.com)
- Testicular cancer is almost always curable if found early, and it is usually curable even when found at a later stage. (lineagotica.info)
- Risk factors for testicular cancer include undescended testis (cryptorchidism), personal or family history of testicular cancer, age, ethnicity, and infertility. (aafp.org)
- Surgical correction of an undescended testis (orchiopexy) before puberty appears to lower the risk of testis cancer, but this isn't certain. (uwhealth.org)
- An estimated 177,800 new cases of cancer will be diagnosed in Canada (not including approximately 74,100 cases of non-melanoma skin cancer). (cancer.ca)
- Melanoma has a 5-year relative survival rate of around 92 and 97 percent at stages 1A and 1B respectively. (medicalnewstoday.com)
- Melanoma is a cancer of the skin, and it has a high survival rate because it is easy to detect in this part of the body. (medicalnewstoday.com)
- In five cancers - breast, prostate, thyroid, testicular and skin melanoma - American survival rates are higher than 90 percent. (lifeethics.org)
- In addition, survival improvements in brain cancer, colorectal cancer, melanoma, stomach cancer, and testicular cancer appear to be greater among whites than among other racial/ethnic groups. (sciencecodex.com)
- Melanoma rates are highest among white women and men. (usc.edu)
- More affluent adolescents and young adults tend to have higher rates of melanoma. (usc.edu)
- Transformative advances in cancer immunotherapy have led to complete remissions and apparent cures for some patients with advanced melanoma or lung cancer. (umn.edu)
- For this retrospective descriptive study, data was retrieved from medical records from every patient diagnosed with testicular cancer between the years 1978-2019 in our center, and their death certificates were assessed for comparison. (peertechz.com)
- Medical records, both in paper and electronic formats, and follow-up protocols of every patient diagnosed with testicular cancer between the years 1978-2019 at the Military Hospital of Santiago were revised. (peertechz.com)
- Testicular cancer is treatable, and with early treatment, the survival rate is high. (doctorshealthpress.com)
- Prostate cancers either grow very slowly or do not grow at all, and they are very treatable. (medicalnewstoday.com)
- Is testicular cancer treatable? (thedogvisitor.com)
- And if it is cancer, it is actually highly treatable so long as it has been caught early enough. (tips.today)
- The longer the testicle remains undescended, the lower the rate of fertility. (aafp.org)
- Secondly, since these men are at increased risk for testicular cancer, moving the testicle to the scrotum permits screening by palpation. (aafp.org)
- Ten percent of males diagnosed with testicular cancer give a history of recent trauma to the testicle. (aafp.org)
- One of the most obvious possible symptoms of testicular cancer is a lump in the testicle area. (doctorshealthpress.com)
- Having or have had an undescended testicle can also raise your chances or getting testicular cancer. (doctorshealthpress.com)
- It's more common among men under 45, with a higher risk among those born with an undescended testicle or those with a close relative with the disease. (mirror.co.uk)
- Currently, testicular cancer patients first undergo surgical removal of the affected testicle. (doctorslounge.com)
- Undescended testicle at birth - regardless if surgically corrected, there is an increased risk for cancer to occur in the testicle not descended at birth. (thomasahleringmd.com)
- Testicular cancer treatment begins with removing the cancerous testicle. (thomasahleringmd.com)
- Cancers in the testicle are classified within one of two tumor types. (thomasahleringmd.com)
- In the stage I of testicular cancer, tissues close to the testicle are attacked first. (onco.com)
- More generally, if a young adult or adolescent has a single enlarged testicle, which may or may not be painful, this should give doctors a reason to suspect testicular cancer. (siddhaspirituality.com)
- Testicular cancer begins when healthy cells in a testicle change and grow out of control, forming a mass called a tumor. (lineagotica.info)
- Testicular cancer incidence and rates of mortality in the United States, 1973 to 1995. (aafp.org)
- these figures coincide with a 20% decrease in cancer mortality from 1950 to 2014. (wikipedia.org)
- Here is a look at the ten cancers with the lowest known mortality rates in the US. (worldatlas.com)
- Testicular Cancer Mortality in Chile: Is it as high as we think? (peertechz.com)
- According to the GLOBOCAN database, Chile has the highest mortality rate worldwide, without a clear explanation of why this is the case. (peertechz.com)
- Chile has the highest mortality rate for testicular cancer worldwide. (peertechz.com)
- A possible explanation for the high mortality in Chile could be an incorrect registration of testicular cancer as cause of death. (peertechz.com)
- Despite of this, Chile is the country with the highest mortality rate in the world according to the Globocan database . (peertechz.com)
- The veracity of its high mortality rate has remained unexplored and rises questions. (peertechz.com)
- The objective of the present study is to expose the mortality of testicular cancer in a chilean center during a 41 year period, and compare it to what is described at the national level. (peertechz.com)
- Mortality (overall, cancer-specific, from other causes) and cancer recurrence. (nih.gov)
- For many cancer survivors, there is little evidence to date to indicate that particular dietary behaviours influence outcomes with regard to recurrence and mortality. (nih.gov)
- In 160 of the United States' approximately 3,000 counties, cancer mortality rose substantially during the same time period. (technologynetworks.com)
- In 2014, for example, the county with the highest overall cancer mortality had about 7 times as many cancer deaths per 100,000 residents as the county with the lowest overall cancer mortality. (technologynetworks.com)
- Although disparities in cancer incidence and mortality have been well documented, Ali Mokdad, Ph.D., who led the study, said that the magnitude of the disparities seen in this study "was a surprise. (technologynetworks.com)
- To conduct the study, Dr. Mokdad and his colleagues analyzed data on deaths from 29 cancer types recorded by the National Center for Health Statistics (NCHS) of the Centers for Disease Control and Prevention and compared the data to population counts collected from the Census Bureau, the NCHS, and the Human Mortality Database. (technologynetworks.com)
- Overall, the researchers found that U.S. cancer mortality rates dropped from about 240 cancer deaths per 100,000 people in 1980 to 192 per 100,000 in 2014. (technologynetworks.com)
- In 1980, the lowest county-level mortality rate was about 130 per 100,000 and the highest was about 380 per 100,000. (technologynetworks.com)
- In 2014, the county with the lowest overall cancer mortality saw about 70 deaths from cancer per 100,000 people, and the county with the highest mortality had more than 500 deaths per 100,000 residents. (technologynetworks.com)
- County-level variations in these factors reflected trends the researchers saw in mortality from individual cancer types. (technologynetworks.com)
- Analyzing cancer mortality on a more granular level is important, said Eric Durbin, Dr.P.H., director of Cancer Informatics for the Kentucky Cancer Registry at the University of Kentucky Markey Cancer Center. (technologynetworks.com)
- Having regional data on outcomes like cancer mortality can help researchers develop and test interventions, he continued. (technologynetworks.com)
Sign of testicular cancer1
Symptom of testicular cancer1
- Even though my prognosis was good, knowing that you have cancer is really scary, and the key thing for me was to get back to normality as soon as possible. (doctorslounge.com)
- Understanding the stage of cancer is a crucial aspect in determining a patient's prognosis and developing a personalized treatment plan. (newhopemedicalcenter.com)
- Testicular cancer carries a good prognosis, with survival rates over 70% at any stage. (peertechz.com)
- Testicular cancer is generally known as a good prognosis malignancy, with survival rates higher than 70%, even in advanced stages [1- (peertechz.com)
- 9 ] For patients with nonseminomas, the degree of tumor-marker elevation after the cancerous testicular has been removed is one of the most significant predictors of prognosis. (uwhealth.org)
- If the cancer is localized (has not spread), the prognosis is usually good. (thedogvisitor.com)
- Prognostic - Some clinical findings such as high systolic blood pressure or poor glucose tolerance may be symptomless and yet carry an adverse prognosis. (bmj.com)
Develop testicular cancer1
- In this article, we'll cover the basic information you need to know about testicular cancer month-from testicular cancer information, why testicular cancer awareness is important, testicular cancer symptoms, and tips for self-examination. (doctorshealthpress.com)
- Unfortunately, one of the main reasons there is such a need for testicular cancer awareness is the fact that many men tend to ignore medical symptoms, especially if it might have anything to do with their sexual organs. (doctorshealthpress.com)
- Hopefully, men will pay attention to International Testicular Cancer Month and start to be more aware of the issue, as well as become familiar with all of the symptoms and risk factors that are involved. (doctorshealthpress.com)
- One of the best ways of detecting testicular cancer early, is to know and recognize the possible symptoms. (doctorshealthpress.com)
- Those men who are HIV-positive must also be on the look out for testicular cancer symptoms as HIV increases your risk for that. (doctorshealthpress.com)
- Caucasian men are more prone to getting testicular cancer than other races, but that doesn't mean you still shouldn't get yourself checked out if you have any of the symptoms we mentioned above. (doctorshealthpress.com)
- Some people who are diagnosed with thyroid cancer are surprised because they may have had no noticeable symptoms. (worldatlas.com)
- The main reasons for this were that they believed it was the cancer they were most likely to die from (57 per cent) or that it had the worst symptoms (47 per cent). (healthcanal.com)
- It is important, not just for diabetics but for everyone to be aware of what the signs and symptoms of mouth cancer are. (express.co.uk)
- The leukemia (cancer) cells go into the blood after starting in the bone marrow, and usually slowly build up over time, with most patients not even having any symptoms for years. (healthician.org)
- One of the first symptoms of testicular cancer is often a lump or swelling in the testes. (siddhaspirituality.com)
- Colon cancer is the second-leading cancer killer of men and women combined, and is among the most difficult to detect because it lacks symptoms in early stages. (texasoncology.com)
- One factor that has a significant effect on survival rates is the latency period between initial asbestos exposure and the appearance of symptoms. (mesotheliomasymptoms.com)
- By the time doctors diagnose the symptoms properly, the cancer is often in an advanced stage . (mesotheliomasymptoms.com)
- While not a very common form of the disease, it is still important for men to be aware of the signs and symptoms of testicular cancer. (tips.today)
- At the same time, other symptoms are very clear indicators of a testicular problem. (tips.today)
- Some of signs and symptoms are often seen in people with testicular cancer and often indicative of a more serious problem. (tips.today)
- Neither of these symptoms automatically means that you have testicular cancer, however. (tips.today)
- Similarly, you may have completely different symptoms and still have this type of cancer. (tips.today)
- At the same time, it is possible that men experience those symptoms but something different from cancer might be present. (tips.today)
- In the vast majority of cases, the signs and symptoms of testicular cancer are actually caused by far more benign and far less serious conditions than cancer. (tips.today)
Stage 2 testicul1
- Thyroid cancer has a 5-year relative survival rate of 98-100 percent at stages 1 and 2. (medicalnewstoday.com)
- Diagram showing stage thyroid cancer at the earliest stage. (worldatlas.com)
- If you have thyroid cancer, you have a good chance of beating it. (worldatlas.com)
- There were no differences in survival between the time periods for adolescents and young adults with bone/soft tissue sarcoma, ovarian carcinoma, ovarian germ cell tumor, stomach cancer, testicular cancer, thyroid cancer, and uterine cancer. (sciencecodex.com)
- Thyroid cancer incidence rates are increasing, especially among women, and is highest among Filipinas and Vietnamese. (usc.edu)
- While thyroid cancer is usually responsive to treatment, there can be long-term side effects. (usc.edu)
- This year, the group-which includes MHN, the Men's Health Initiative, the Testicular Cancer Foundation, the Prevent Cancer Foundation, and the American Oncology Association, among others-will continue its call for awareness and also highlight the impact the disease has on the quality of life of patients, survivors, and their families. (menshealthnetwork.org)
- Family physicians often play a role in the care of cancer survivors and should be familiar with monitoring for recurrence and future complications, including secondary malignant neoplasms, cardiovascular risk, and infertility and subfertility. (aafp.org)
- At the beginning of 2007, there were about 749,000 cancer survivors or people currently undergoing cancer treatment (about one in 44, or 2.3% of the Canadian population) who had been diagnosed with cancer in the previous 10 years. (cancer.ca)
- Without early detection, the five-year survival rate for mouth cancer is only 50 per cent but if it is caught early, survival rates can dramatically improve to up to 90 per cent, as well as the quality of life for survivors being significantly increased. (express.co.uk)
- During April, these organizations are calling for increased research and greater awareness of the challenges facing testicular cancer patients, survivors, and their loved ones. (menshealthnetwork.org)
- Evidence from studies among other cancer survivors was too limited or could not be identified. (nih.gov)
- Notwithstanding, limited evidence suggests that a low-fat diet, a high-quality diet and a prudent diet are beneficial for breast cancer survivors, while a Western diet is detrimental for breast cancer survivors. (nih.gov)
- MATERIAL AND METHODS: In this cross-sectional study, testicular cancer survivors diagnosed in the period 1984-2007 from the Danish Testicular Cancer database completed a questionnaire on health behaviours (2014-2016). (bvsalud.org)
- 1.10, 95% CI: 1.01-1.20) among testicular cancer survivors than in the reference population. (bvsalud.org)
- CONCLUSION: We identified smoking cessation as primary target for intervention studies in testicular cancer survivors. (bvsalud.org)
- PURPOSE: To evaluate neurotoxicity in testicular cancer survivors (TCSs) years after treatment and secondly the influence of neurotoxicity on quality-of-life (QoL). (bvsalud.org)
- She initially had a hard time adjusting to her "new body" and joined a support group for breast cancer patients and survivors. (oralcancerfoundation.org)
Last 40 years2
- What's heartening is that overall survival from all cancers has doubled over the last 40 years and this optimistic message is reaching the public who have rightly picked breast and testicular cancer which are both cancers with high survival rates. (healthcanal.com)
- In the last 40 years, testicular cancer rates in Caucasians has doubled for no identifiable reason. (thomasahleringmd.com)
- A study of the utility of LDH in 499 patients with testicular germ cell tumor undergoing surveillance after orchiectomy or after treatment of stage II or III disease reported that 7.7% of patient visits had elevations in LDH unrelated to cancer, whereas only 1.4% of visits had cancer-related increases in LDH. (uwhealth.org)
- BACKGROUND: Cancer-specific survival for men with clinical stage I (CSI) seminoma approaches 100%, regardless of the management approach chosen after orchiectomy. (bvsalud.org)
- The central hypothesis of this observation asserted that these disorders may all collectively signify testicular dysgenesis syndrome (TDS). (frontiersin.org)
- Testicular cancer, cryptorchidism, hypospadias, and poor semen quality make up the syndrome known as testicular dysgenesis syndrome. (siddhaspirituality.com)
- The 111 trial, led by the Institute of Cancer Research (ICR), London, and the University Hospital's Birmingham National Health Service Foundation Trust, studied 250 men with early-stage testicular cancer who faced a high risk of recurrence following surgery. (ajmc.com)
- Moreover, epidemiological studies have suggested that ultraviolet-B exposure can help reduce cancer risk and prevalence, indicating a potential role for vitamin D as a feasible agent to prevent cancer incidence and recurrence. (mdpi.com)
- however, 4 patients with transscrotal violations showed a significantly higher rate of disease recurrence. (elsevier.com)
- Cryptorchidism is the most significant risk factor for testicular cancer, increasing the risk up to 11-fold. (aafp.org)
- The risk factors associated with testicular cancer include white race, cryptorchidism, testicular atrophy or dysgenesis, and family history. (aafp.org)
- A male with a history of cryptorchidism has a risk of developing testicular cancer that is 2.5- to 11-fold greater than that of an unaffected male. (aafp.org)
- In recent times, progressive increases in the incidence of male reproductive disorders inclusive of hypospadias, cryptorchidism, poor semen quality, and testicular cancer, suggested a common foetal origin. (frontiersin.org)
- A major risk factor for the development of testis cancer is cryptorchidism. (siddhaspirituality.com)
- Seminomas, which account for 50 percent of all testicular cancer types, are slow growing and highly responsive to treatment. (thomasahleringmd.com)
- Seminomas and nonseminomas alike may result in elevated lactate dehydrogenase (LDH) but such values are of less clear prognostic significance because LDH may be elevated in many different conditions unrelated to cancer. (uwhealth.org)
- The 2 most common types of testicular cancer are: Seminomas. (thedogvisitor.com)
- Meanwhile, the cancer becomes more advanced when it spreads to the lymph nodes and other organs. (newhopemedicalcenter.com)
- Even when these sarcomas have not yet spread to lymph nodes, the risk of spread (to lymph nodes or distant sites) is very high. (thedogvisitor.com)
- When testicular cancer spreads, it most commonly spreads to the lung and the lymph nodes of the chest, pelvis, and the base of the neck. (thedogvisitor.com)
- Testicular mesothelioma , otherwise known as mesothelioma of the tunica vaginalis testis, is a rare cancer that forms on the membrane lining the testes. (newhopemedicalcenter.com)
- Testicular cancer is a condition occurring in men when uncontrolled cell growth, or cancer, takes place in the testes. (thomasahleringmd.com)
- No major increases in death rates for most cancers were observed, although the liver cancer death rate has been increasing 1.8% per year. (cancer.ca)
- No major increases in death rates for most cancers were observed, although the lung and liver cancer death rates in particular have been increasing by 1% and 1.6% per year, respectively. (cancer.ca)
- Smoking increases the risk of lip cancer. (worldatlas.com)
- A new study in JNCI Cancer Spectrum finds that dramatic increases in cancer survival in adolescents and young adults are undermined by continuing disparities by race, ethnicity, and socioeconomic status. (sciencecodex.com)
- The patterns here suggest that most of the recent survival increases in this age group were driven by improvements in treatments for HIV/AIDS and related cancers. (sciencecodex.com)
- An initial epidemiological study of reproductive outcome measured in the population who drank contaminated water showed increases in the rates of spontaneous abortion and congenital malformations of infants exposed during pregnancy. (alexanderlaw.com)
- However, funding for the National Institutes of Health (NIH) has been largely flat for the past 15 years, with increases falling below the rate of inflation. (umn.edu)
- Increases in pancreatic cancer survival are mirrored by increases in survival from other cancer types. (pancreaticcanceraction.org)
- New Hope Unlimited offers pioneering treatments for testicular mesothelioma, some of which are not available at most cancer centers in the world. (newhopemedicalcenter.com)
- To do this, we integrate conventional and alternative mesothelioma treatments that target the root of cancer with minimal short- and long-term side effects. (newhopemedicalcenter.com)
- Sarcoma UK is a national charity that funds vital research, offers support for anyone affected by sarcoma cancer and campaigns for better treatments. (gponline.com)
- However, the benefits of cancer treatments may hide some risks. (frontiersin.org)
- Advanced medical treatments are prescribed by the cancer specialist to cure for the patient with first stage testicular cancer. (onco.com)
- It is likely that improving surgical procedures, chemotherapies and other treatments have helped boost survival. (pancreaticcanceraction.org)
- At this stage, doctors do not consider it to be cancerous, but it can indicate very early signs of cancer. (medicalnewstoday.com)
- If you have been diagnosed with breast cancer in situ, it means that the milks ducts of your breast have developed cancerous tissue. (worldatlas.com)
- If you're overweight, you have an increased risk of colon , kidney , and esophageal cancer (not to mention other non-cancerous health issues). (texasoncology.com)
- For starters, testicular cancer can't be easily diagnosed via a biopsy-the removal of a tiny piece of a potentially cancerous tissue for testing-because it could cause the cancer to spread. (bottomlineinc.com)
- This is the most common form of the cancer and develops when the mesothelial cells that line the pleura become cancerous and divide uncontrollably. (asbestos.com)
- In the new study, Huddart's group tracked outcomes for nearly 250 men with early-stage testicular cancer that was at high risk of returning after surgery. (doctorslounge.com)
- Thereafter several groups worked to improve outcomes for adolescents and young adults with cancer. (sciencecodex.com)
- The largest risk factor for death in adolescents and young adults was stage of disease, with those with advanced stage cancer having the worst outcomes. (sciencecodex.com)
- A number of studies and a growing body of evidence indicates that high hospital and surgeon volume can be associated with improved outcomes for a number of surgical diseases. (blogspot.com)
- The National Cancer Institute estimate that doctors will diagnose 1,735,350 new cases across the U.S. in 2018 and that 609,640 people will die from cancer in this year. (medicalnewstoday.com)
- On Monday, July 9th 2018 President Donald Trump signed legislation requiring the CDC to set up a registry of firefighters external icon that will track links between their workplace exposures and cancer. (cdc.gov)
- The most common cancer among women in the United States is breast cancer (123.7 per 100,000), followed by lung cancer (51.5 per 100,000) and colorectal cancer (33.6 per 100,000), but lung cancer surpasses breast cancer as the leading cause of cancer death among women. (wikipedia.org)
- After reaching a peak in 1988, the cancer death rate in Canadian men has declined, mainly due to downward trends in prostate, lung and colorectal cancers. (cancer.ca)
- Testicular cancer accounts for only about 1 percent of all cancers in males. (aafp.org)
- Testicular cancer is the most common solid tumor among males 15 to 34 years of age, with an estimated 8,850 new cases and 410 deaths during 2017 in the United States. (aafp.org)
- Testicular cancer is the most common solid tumor among males 15 to 34 years of age. (aafp.org)
- This latest study looking at the more recent time period from 1988-2014 shows that among 30 to 34 year olds with cancer, the 5- year survival rate increased by 20.6% in males and 4.2% in females from 1988-2000 to 2001-2014. (sciencecodex.com)
- Among 35 to 39 year olds the 5-year survival rate increased by 18.9% in males and 4.2% in females. (sciencecodex.com)
- Among males of all ages, survival improvement was greatest for adolescents and young adults. (sciencecodex.com)
- It appears the negative survival improvement gap observed in this age group from 1977 to 1997 was essentially driven by the rise and height of HIV/AIDs related cancers in males. (sciencecodex.com)
- Similarly, the dramatic survival improvement researchers here found among adolescents and young adults in this study from 1988 to 2014, especially among males, was the result of the baseline survival corresponding to the height of the HIV/AIDS epidemic. (sciencecodex.com)
- 60% of the males survived after the testicular relapse. (nih.gov)
- Among those statistics, one in six African-American men will develop the disease in his lifetime, which is almost two times the rate of white males. (menshealthnetwork.org)
- MHN encourages boys and men of this age group to regularly perform testicular self-exams, and if they feel a lump/bump, to tell someone and see a doctor immediately. (menshealthnetwork.org)
- Breast cancer is abnormal growth of cells in the breast tissue, with signs such as a lump in the breast, dimpling of the skin, a change in breast shape, a red scaly patch of skin or fluid coming from the nipple. (healthician.org)
- The main way testicular cancer diagnosed is via a lump or mass inside a testis. (siddhaspirituality.com)
- Does bladder cancer spread quickly? (thedogvisitor.com)
- Half of all cases are found when the cancer is still only in the bladder, but 4 percent of diagnoses are made after bladder cancer has spread to distant tissues. (thedogvisitor.com)
- Bladder cancer is characterized by the abnormal growth of cells in the bladder lining, with the tumor sometimes spreading into the surrounding organs. (healthician.org)
- West Highland Terriers are known for developing bladder cancer. (sooperarticles.com)
- Speaking in the institute news release, Taylor said he'd "already had to have time off for surgery, so when I was offered the chance to have less chemo but with no greater risk the cancer would return, I jumped at it. (doctorslounge.com)
- The report The Loneliest Cancer finds that even those who are successfully treated can suffer life changing after-effects, due to the aggressive nature of surgery including amputation. (gponline.com)
- Several types of cancer are associated with high survival rates, including breast, prostate, testicular and colon cancer. (wikipedia.org)
- In cancer types with high survival rates, incidence is usually higher in the developed world, where longevity is also greater. (wikipedia.org)
- In general, the incidence and death rates for the majority of cancer types have stabilized or declined during the past decade. (cancer.ca)
- To understand the difference in outlook between cancer types, researchers often use a statistic called the 5-year survival rate. (medicalnewstoday.com)
- In this article, we look at the seven types of cancer that have the highest 5-year relative survival rates. (medicalnewstoday.com)
- Doctors can isolate and treat these types of breast cancer before they develop into more severe forms of cancer. (medicalnewstoday.com)
- Skin cancer can come in many forms, and some types have higher recovery rates than others. (worldatlas.com)
- Breast cancer is one of the most highly publicized types of cancer, with many fundraising campaigns targeted towards gathering additional funds to drive research towards a cure. (worldatlas.com)
- When asked "And which ONE, if any, of the following types of cancer do you MOST fear getting? (healthcanal.com)
- It is the only cancer charity in the UK focusing on all types of sarcoma. (gponline.com)
- Cancer types showing the greatest improvement in survival between the two time periods were Kaposi sarcoma, chronic myeloid leukemia, and non-Hodgkin lymphoma. (sciencecodex.com)
- There were no cancer types that had worse survival after adjusting for cancer and demographic factors. (sciencecodex.com)
- There are several different types of testicular cancer. (first4lawyers.com)
- Different types of cancer exist, and is named depending on the area of the body affected. (healthician.org)
- This means that the cancer does not include any of the types of tumor listed below. (lineagotica.info)
- For some types of cancer, the word 'cure' is almost a reality - 96% of men with testicular cancer are now cured. (djsresearch.co.uk)
- Testicular cancer is less "serious" than other types of cancers. (bottomlineinc.com)
- Biopsies do not cause most other types of cancer to spread. (bottomlineinc.com)
- There are four different types of this type of cancer, and two types, pleural and peritoneal, are addressed in the graph. (asbestos.com)
People who are diagnosed1
- WASHINGTON - Men's Health Network (MHN) is partnering with a coalition of health organizations focused on raising awareness during Testicular Cancer Awareness Month this April. (menshealthnetwork.org)
- It is great to join forces with the Men's Health Network for Testicular Cancer Awareness Month," said Connor O'Leary, Chief Mission Officer of the Testicular Cancer Foundation. (menshealthnetwork.org)
- What is the Testicular Cancer Awareness Month color? (doctorshealthpress.com)
- April is International Testicular Cancer Awareness Month, and it's time to get down to your skivvies and get yourself tested. (doctorshealthpress.com)
- Testicular cancer affects many men from around the globe, and hopefully, by the end of this piece, you will have a better understanding of why International Testicular Cancer Awareness month is so important to get the word out. (doctorshealthpress.com)
- Men's Health Network (MHN) has joined with other cancer organizations to form an awareness coalition to recognize Testicular Cancer Awareness Month. (menshealthnetwork.org)
- Timely detection of improvements in long-term survival rates also adds to the value of cancer surveillance as a basis for appropriate public-health decisions. (eurekalert.org)
- Published this year, " Cancer in Los Angeles County: Trends Among Adolescents and Young Adults 1988-2011 " is a large-scale, comprehensive evaluation of the cancer trends of 15- to 39-year- olds, said Dennis Deapen, lead author of the report and director of the Los Angeles Cancer Surveillance Program. (usc.edu)
- For the past 44 years, the Los Angeles Cancer Surveillance Program has tracked every diagnosed case of cancer. (usc.edu)
Spread to other organs1
- Although testicular cancer accounts for about 1 percent of all male cancers, it is the most common form of cancer among men between 15 and 35 years old. (menshealthnetwork.org)
- However, survival rates are currently often measured in terms of 5-year survival rates, which is the percentage of people who live at least five years after being diagnosed with cancer, and relative survival rates compare people with cancer to people in the overall population. (wikipedia.org)
- Brain and pancreatic cancers have much lower median survival rates which have not improved as dramatically over the last forty years. (wikipedia.org)
- Despite substantial investment and years of research worldwide, cancer remains the leading cause of death in the United States. (medicalnewstoday.com)
- However, cancer can return after remission, sometimes many years later. (medicalnewstoday.com)
- Therefore, people with this stage and type of cancer are almost 100 percent as likely to survive for at least 5 years as people without the condition. (medicalnewstoday.com)
- The five-year survival rate for testicular cancer is 95.1%, and at ten years, men face a 94.6% survival rate. (worldatlas.com)
- European women are only 55.8 percent likely to live five years after contracting any kind of cancer, compared to 62.9 percent for American women. (lifeethics.org)
- Our latest figures show more than 80 per cent of women now survive their breast cancer for five years or more. (healthcanal.com)
- According to the Department of Statistics and Information of the Ministry of Health of Chile (DEIS), testicular cancer deaths averaged 94 deaths per year between the years 2003-2007 and during that same time period the Chilean Cancer Poblational Registry reported 7.8 new cases for every 100.000 men per year . (peertechz.com)
- Of 440 men treated in Scotland , 87% of 235 men treated at the highest volume center were alive at 5 years. (blogspot.com)
- Testicular cancer (TC) is the most frequent solid malignancy in young men aged between 15 and 40 years. (frontiersin.org)
- That is, 99 out of 100 men treated for testicular cancer at this stage have survived more than 5 years. (onco.com)
- The value of event-free survival (EFS)+/-s.e. was 67.2+/-2.2% at 10 years in L84-11, which was not improved in the following two studies, and eventually improved to 75.0+/-1.8% at 10 years in L95-14 study. (nih.gov)
- 2000. Chronic exposures particularly in the workplace, on a day to day basis over a period of years, are the most significant cause of cancer, not the workers' genetic code. (alexanderlaw.com)
- For unknown reasons, the number of testicular cancer cases has increased for the past 40 years. (lineagotica.info)
- Even for cancers typically diagnosed in later years, like lung cancer, prevention begins early. (texasoncology.com)
- Charity, Cancer Research UK, recently released findings which show that the ten year survival rates have increased by almost a third (30%) in the past forty years. (djsresearch.co.uk)
- Most people with testicular cancer go on to live a full, healthy, and happy life and the survival rate of five years is the highest for all forms of cancer, which is certainly good news for men with this type of cancer. (tips.today)
- 10 years ago, when Pancreatic Cancer Action was founded, survival was around 3% and had not increased in years. (pancreaticcanceraction.org)
- The American Cancer Society reports 5-year relative survival rates of over 70% for women with stage 0-III breast cancer with a 5-year relative survival rate close to 100% for women with stage 0 or stage I breast cancer. (wikipedia.org)
- Relative survival is lowest for lung, esophagus and pancreas cancers, which all have survival rates of 16% or lower. (cancer.ca)
- Overall, relative survival has improved from 56% in 1992-94 to 62% in 2004-06. (cancer.ca)
- To provide a more accurate estimate of the outlook for cancer, doctors can also refer to 5-year relative survival rates. (medicalnewstoday.com)
- Relative survival rates compare people with a specific disease to those in the general population without the disease. (medicalnewstoday.com)
- The 5-year relative survival rate for stage 0 and 1 breast cancer is 99-100 percent . (medicalnewstoday.com)
- Prostate cancers have a 99 percent 5-year relative survival rate at stages 1 and 2. (medicalnewstoday.com)
- The graph featured depicts the five-year relative survival rate for mesothelioma in five year increments from 1975 through 2000. (asbestos.com)
- The good news is that testicular cancer, if caught early, has a 99 percent five-year survival rate," said Ana Tomsic, Vice President of MHN. (menshealthnetwork.org)
- the five-year survival rate now exceeds 95 percent. (aafp.org)
- The five-year survival rate for breast cancer is 26% according to Cancer Centers of America's website. (wikipedia.org)
- Small cell lung cancer has a five-year survival rate of 4% according to Cancer Centers of America's Website. (wikipedia.org)
- New statistics published by the Lancet Oncology show the 5-year survival rate for pancreatic cancer to have risen to a record high, 7.9%, in the UK. (pancreaticcanceraction.org)
- Whites, Hispanics, and American Indian/Alaska Natives have the highest rates of testicular cancer. (aafp.org)
- For every racial/ethnic minority group compared to whites, survival disparities for all cancers combined worsened over time. (sciencecodex.com)
- Rates are more than five times higher among whites than blacks. (usc.edu)