Monosaccharide Transport Proteins
Glucose
3-O-Methylglucose
Fructose
Glucose Transporter Type 5
Glucose Transport Proteins, Facilitative
Pentose Phosphate Pathway
An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.
Galactose
An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
Cyclin-Dependent Kinase Inhibitor p57
Hexokinase
An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. (From Enzyme Nomenclature, 1992) EC 2.7.1.1.
Ranunculaceae
Biological Transport
Carbohydrate Metabolism
Glucose-6-Phosphate
Glycolysis
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
Biological Transport, Active
Glucose-6-Phosphate Isomerase
An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.
Mannose
Transaldolase
Monosaccharides
Glucose Transporter Type 2
Glucose Transporter Type 1
Sucrose
Carbohydrates
Carbon Isotopes
Sodium-Glucose Transporter 1
Maltose
Chlorella
Phosphogluconate Dehydrogenase
Fructokinases
Phosphofructokinase-1
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
Intraerythrocytic Plasmodium falciparum expresses a high affinity facilitative hexose transporter. (1/840)
Asexual stages of Plasmodium falciparum cause severe malaria and are dependent upon host glucose for energy. We have identified a glucose transporter of P. falciparum (PfHT1) and studied its function and expression during parasite development in vitro. PfHT1 is a saturable, sodium-independent, and stereospecific transporter, which is inhibited by cytochalasin B, and has a relatively high affinity for glucose (Km = 0.48 mM) when expressed in Xenopus laevis oocytes. Competition experiments with glucose analogues show that hydroxyl groups at positions C-3 and C-4 are important for ligand binding. mRNA levels for PfHT1, assessed by the quantitative technique of tandem competitive polymerase chain reaction, are highest during the small ring stages of infection and lowest in gametocytes. Confocal immunofluorescence microscopy localizes PfHT1 to the region of the parasite plasma membrane and not to host structures. These findings have implications for development of new drug targets in malaria as well as for understanding of the pathophysiology of severe infection. When hypoglycemia complicates malaria, modeling studies suggest that the high affinity of PfHT1 is likely to increase the relative proportion of glucose taken up by parasites and thereby worsen the clinical condition. (+info)Effect of dietary taurine supplementation on GSH and NAD(P)-redox status, lipid peroxidation, and energy metabolism in diabetic precataractous lens. (2/840)
PURPOSE: To evaluate changes in glutathione and NAD(P)-redox status, taurine and malondialdehyde (MDA) levels, glucose utilization, and energy metabolism in diabetic precataractous lenses and to assess whether these changes can be prevented with dietary taurine supplementation. METHODS: The experimental groups included control and streptozotocin-diabetic rats with a 3-week duration of diabetes fed unsupplemented or taurine (1% or 5%)-supplemented diets. The levels of glucose, sorbitol, fructose, myo-inositol, oxidized glutathione (GSSG), glycolytic intermediates, malate, alpha-glycerophosphate, and adenine nucleotides were assayed in individual lenses spectrofluorometrically by enzymatic methods, reduced glutathione (GSH) spectrofluorometrically with O-phthaldialdehyde, MDA colorimetrically with N-methyl-2-phenylindole, and taurine by high-performance liquid chromatography. Free cytosolic NAD+/NADH and NADP+/NADPH ratios were calculated from the lactate dehydrogenase and malic enzyme systems. RESULTS: Sorbitol pathway metabolites and MDA were increased, and GSH and taurine levels were reduced in diabetic rats versus controls. The profile of glycolytic intermediates (an increase in glucose 6-phosphate, no change in fructose 6-phosphate and fructose 1,6-diphosphate, an increase in dihydroxyacetone phosphate, a decrease in 3-phosphoglycerate, phosphoenolpyruvate, and pyruvate, and no change in lactate), and a 9.2-fold increase in alpha-glycerophosphate suggest diabetes-induced inhibition of glycolysis. Free cytosolic NAD+/NADH ratios, ATP levels, ATP/ADP, and adenylate charge were reduced, whereas free cytosolic NADP+/NADPH ratios were elevated. Lens taurine levels in diabetic rats were not affected by supplementation with 1% taurine. With 5% taurine supplementation, they were increased approximately 2.2-fold higher than those in untreated diabetics but remained 3.4-fold lower than in controls. Lens GSH levels were similar in diabetic rats fed unsupplemented and 5% taurine-supplemented diets, whereas GSSG and MDA levels and GSSG/GSH ratios were reduced by 5% taurine supplementation. The decrease in free cytosolic NAD+/NADH, ATP/ADP, and adenylate energy charge were ameliorated by 5% taurine supplementation, whereas accumulation of sorbitol pathway intermediates, depletion of myoinositol, inhibition of glycolysis, a decrease in ATP and total adenine nucleotide, and an increase in free cytosolic NADP+/NADPH were not prevented. CONCLUSIONS: Dietary taurine supplementation ameliorates MDA levels, GSSG/GSH, and NAD+/NADH and fails to prevent the osmotically mediated depletion of GSH and taurine and the decrease in glucose utilization and ATP levels in diabetic precataractous lens. Dietary taurine supplementation cannot be regarded as an alternative to aldose reductase inhibition in eliminating antioxidant and metabolic deficits contributing to diabetes-associated cataractogenesis. (+info)Polyol formation and NADPH-dependent reductases in dog retinal capillary pericytes and endothelial cells. (3/840)
PURPOSE: Dogs fed a diet containing 30% galactose experience retinal vascular changes similar to those in human diabetic retinopathy, with selective pericyte loss as an initial lesion. In the present study the relationship among reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent reductases, polyol formation, and flux through the polyol pathway in cultured dog retinal capillary cells were investigated. METHODS: Pericytes and endothelial cells were cultured from retina of beagle dogs. NADPH-dependent reductases were characterized by chromatofocusing after gel filtration. Sugars in cultured cells were analyzed by gas chromatography, and flux through the polyol pathway was investigated by 19F nuclear magnetic resonance (NMR) with 3-fluoro-3-deoxy-D-glucose (3FG) as a substrate. The presence of aldose reductase and sorbitol dehydrogenase in these cells was examined by northern blot analysis. RESULTS: Two distinct peaks corresponding to aldose reductase and aldehyde reductase, the latter being dominant, were observed in pericytes by chromatofocusing. Culture in medium containing either 10 mM D-galactose or 30 mM D-glucose resulted in the accumulation of sugar alcohol in pericytes that was markedly reduced by aldose reductase inhibitors. 19F NMR spectra obtained from pericytes cultured for 5 days in medium containing 2 mM 3FG displayed the marked accumulation of 3-fluoro-deoxysorbitol but not 3-fluoro-deoxyfructose. No 3FG metabolism was observed in similarly cultured endothelial cells. With northern blot analysis, aldose reductase was detected in pericytes but not in endothelial cells. Sorbitol dehydrogenase was below the detectable limit in pericytes and endothelial cells. CONCLUSIONS: Aldose, aldehyde, and glyceraldehyde reductases are present in dog retinal capillary pericytes, with aldehyde reductase being the major reductase present. Polyol accumulation easily occurs in pericytes but not in endothelial cells. (+info)Carbon assimilation by Claviceps purpurea growing as a parasite. (4/840)
Carbon assimilation by Claviceps purpurea, growing as a parasite on cereals, has been investigated by supplying the host plant with 14CO2 in a closed system. The presence of the pathogen induced the plant to exude photosynthate which contained high levels of sucrose. During the period of 14CO2 supply, 14C was incorporated into the sucrose and so the path of carbon into the parasite could be traced. Hexoses, derived by the action of the fungal sucrase on sucrose, were assimilated by the pathogen and largely converted into polyols - mainly mannitol and, to a lesser extent, trehalose. The rate of carbohydrate metabolism decreased with maturation of the ergot, and also showed qualitative differences between the basal and apical regions of the ergot which were probably a function of nutrient supply. (+info)Involvement of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system in regulation of transcription of catabolic genes. (5/840)
Synthesis of catabolite-sensitive enzymes is repressed in mutants defective in the general proteins (enzyme I and HPr) of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system (ptsI and ptsH mutations). To elucidate the mechanism of this phenomenon we constructed isogenic strains carrying pts mutations as well as different lesions of regulation of the lac operon or mutations affecting adenylate cyclase activity (cya mutation) and synthesis of cyclic AMP-receptor protein (crp mutation) Measurements of the differential rate of beta-galactosidase synthesis in these strains showed that the repressive effect of pts mutations was revealed in lac+, lacI, lacOc and cya bacteria, but it was lost in lacP and crp strains. It was concluded that mutational damage to the general components of the phosphoenolpyruvate-dependent phosphotransferase system diminishes activity of the lac promoter. The results obtained led to the conclusion that pts gene products (apparently phospho approximately HPr) are necessary for the initiation of transcription of catabolite-sensitive operons in E. coli. (+info)Sugars and sugar derivatives which inhibit the short-circuit current of the everted small intestine of the rat. (6/840)
1. The short-circuit current of everted rat intestine supported on a perforated cannula proved to be stable for up to 3 hr and has been used to study competition between transportable and non-transportable sugars. 2. 4,6-O-Ethylidene-alpha-D-glucopyranose (ethylidene glucose) and 4,6-O-benzylidene-e alpha-D-glucopyranos (benzylinene glucose), two nontransportable inhibitors of the hexose transfer system in human erythrocytes, were found to reduce the short-circuit current generated by transportable sugars such as galactose or 3-O-methyl glucose. 3. These compounds were also found to reduce the basal short-circuit current established by the everted intestine in a sugar-free Krebs solution. Both types of inhibition approached saturation at the higher concentrations used. 4. Similar inhibitory properties were shown by mannose, a non-actively accumulated monosaccharide, and by the beta-disaccharides lactose and cellobiose. 5. It is suggested that this common pattern of behaviour is due to the ability of these compounds to react with the sites for active hexose transfer but without translocation by the system. The significance of the inhibition of the basal short-circuit current is briefly discussed in this context. (+info)Structure of the O-specific polysaccharide of a serologically separate strain Proteus penneri 2 from a new proposed serogroup O66. (7/840)
O-specific polysaccharide chain of Proteus penneri strain 2 lipopolysaccharide was studied by full and partial acid hydrolysis, Smith degradation, methylation analysis, and NMR spectroscopy, including two-dimensional rotating-frame NOE spectroscopy (ROESY) and 1H,13C heteronuclear multiple-quantum coherence (HMQC) experiments. Together with D-glucose and 2-acetamido-2-deoxy-D-glucose, the polysaccharide was found to contain two rarely occurring sugars, 6-deoxy-L-talose (L-6dTal) and 2,3-diacetamido-2,3,6-trideoxy-L-mannose (L-RhaNAc3NAc), and the following structure of a non-stoichiometrically O-acetylated tetrasaccharide repeating unit was established: [equation: see text] The O-specific polysaccharide studied has a unique composition and structure and, accordingly, P. penneri 2 is serologically separate among Proteus strains. Therefore, we propose for P. penneri 2 a new Proteus O-serogroup O66 where this strain is at present the single representative. (+info)Structure of the glucan-binding sugar chain of Tip1p, a cell wall protein of Saccharomyces cerevisiae. (8/840)
Tip1p is one of the major cell wall mannoproteins of Saccharomyces cerevisiae and is presumed to be synthesized as a glycosylphosphatidylinositol (GPI)-anchored form. We purified Tip1p from a glucanase extract of yeast cell walls and analyzed the sugar chain involved in the cell wall linkage. One mol of glucanase-extracted Tip1p contained 7.5 mol of glucose derived from glucan and 1 mol of ethanolamine, a component of the GPI anchor. One mol of the C-terminal peptide of Tip1p digested with Achromobacter protease I also contained 7.9 mol of glucose and 1 mol of ethanolamine. On the other hand, Tip1p contained no glucosamine, which is a component of the GPI anchor. The glucan-binding sugar chain of Tip1p was released by hydrazinolysis and isolated. This sugar chain contained ethanolamine with a free amino group and a glucose reducing end, but no mannose reducing end. Phosphodiesterase treatment eliminated the free amino group from this sugar chain, suggesting that a phosphodiester bond exists between the ethanolamine and the glucan remnant. These results indicate (1) the glucan-binding sugar chain of Tip1p is a GPI derivative, and (2) the GPI anchor is cleaved at the glycosyl moiety, and the resultant mannose reducing end is probably used to link Tip1p to cell wall glucan. (+info)
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Galactose
"16.3 Important Hexoses , The Basics of General, Organic, and Biological Chemistry". courses.lumenlearning.com. Retrieved 2022- ...
Furanose
ISBN 0-534-49033-6. (Carbohydrate chemistry, Carbohydrates, Tetrahydrofurans, Hexoses). ...
Aldose-1-phosphate adenylyltransferase
doi:10.1016/0926-6569(64)90337-2. Passeron S, Recondo E, Dankert M (1964). "Biosynthesis of adenosine diphosphate D-hexoses". ...
List of phytochemicals in food
Hexose wheat, barley. Pentose rye, oat. Beta-glucan Chitin fungi includes other edible mushrooms. Lentinan fruit body of ...
Methoxymethylfurfural
Related to the production of furfural, MMF can be produced from C-6 sugars hexoses such as glucose and fructose. It is formed ... Dehydration of hexoses as biosustainable product route. Chemical Reviews submitted. Podesta, Federico; Fajardo, Victor; Freyer ... via the dehydration of the hexoses and subsequent etherification of hydroxymethylfurfural (HMF). Already in 1936 a batch ...
Hydroxyacetone
Nodzu, Ryuzaburo (1935). "On the Action of Phosphate Upon Hexoses. I. The Formation of Acetol From Glucose in Acidic Solution ...
Octose
Heptose Hexose Pentose "Octose". v t e (Monosaccharides, All stub articles, Organic compound stubs). ...
Phosphorylation
ATP-D-glucose 6-phosphotransferase) and non-specific hexokinase (ATP-D-hexose 6-phosphotransferase). In liver, synthesis of ... Chapter 14: Glycolysis and the Catabolism of Hexoses. Garrett R (1995). Biochemistry. Saunders College. "Hexokinase - Reaction ... ATP-D-hexose 6-phosphotransferase). The role of glucose 6-phosphate in glycogen synthase: High blood glucose concentration ...
Sugar
Many pentoses and hexoses can form ring structures. In these closed-chain forms, the aldehyde or ketone group remains non-free ...
Mannitol-1-phosphate 5-dehydrogenase
Wolfe JB; Kaplan NO (1955). Wolff, Johnb; Kaplan, Nathano (eds.). "Hexose phosphate and hexose reductase. A. D-Mannitol-1- ... Other names in common use include hexose reductase, mannitol 1-phosphate dehydrogenase, D-mannitol-1-phosphate dehydrogenase, ...
Tagatose
... is a hexose monosaccharide. It is found in small quantities in a variety of foods, and has attracted attention as an ...
Glutaminolysis
... modulation of hexoses". Experimental Cell Research. 183 (2): 303-318. doi:10.1016/0014-4827(89)90391-1. PMID 2767153. Gardner, ...
GLUT8
Other hexoses are not good substrates of the transporter. Mice devoid of both copies of the SLC2A8 gene are viable, fertile and ... "The SLC2 family of facilitated hexose and polyol transporters" (PDF). Pflügers Arch. 447 (5): 480-9. doi:10.1007/s00424-003- ...
Bial's test
... is used to distinguish pentoses from hexoses; this distinction is based on the color that develops in the presence ... The related hydroxymethylfurfural from hexoses may give a muddy-brown, yellow or gray solution, but this is easily ... Fernell and King published a procedure for simultaneous determination of pentoses and hexoses from measurements at two ... "The simultaneous determination of pentose and hexose in mixtures of sugars". Analyst (78): 80-83. Hanson, R. S.; Phillips, J. A ...
Acidobacteriota
Li, Zijie; Gao, Yahui; Nakanishi, Hideki; Gao, Xiaodong; Cai, Li (2013-11-12). "Biosynthesis of rare hexoses using ...
Lignocellulosic biomass
Unlike hexoses such as glucose, pentoses are difficult to ferment. The problems presented by the lignin and hemicellulose ...
5′-Methylthioadenosine
J. A. Mandel u. E. K. Dunham (1912). "Preliminary note on a purine-hexose compound". J. Biol. Chem. 11: 85-86. doi:10.1016/ ...
Peganum harmala
The nectar is rich in hexose sugars. It contains a relatively small concentration of amino acids among which there is an ...
Glucose-1-phosphatase
Faulkner P (August 1955). "A hexose-1-phosphatase in silkworm blood". The Biochemical Journal. 60 (4): 590-6. doi:10.1042/ ...
Latilactobacillus sakei
It is homofermentative; hexoses are metabolized via glycolysis to lactic acid as main metabolite; pentoses are fermented via ...
Pentose
In the cell, pentoses have a higher metabolic stability than hexoses. A polymer composed of pentose sugars is called a pentosan ... In each of these tests, pentoses react much more strongly and quickly than hexoses. Pentose, Merriam-Webster "D-Ribose". ...
Søren Laland
His thesis was called Studies in Deoxy Hexoses and Deoxypentosenucleic Acids. From 1955 to his retirement he served as a ...
Gamma-Valerolactone
GVL is produced from levulinic acid, which is obtained from hexoses. In a typical process, cellulosic biomasses, such as corn ...
Cortisone reductase deficiency
NADH produced by hexose-6-phosphate is delivered directly to the catalytic site of cortisone reductase. If NADH production is ... Dysregulation of hexose-6-phosphate dehydrogenase occurs as a result of gene mutation. Cortisol is important in signalling ... Hewitt, K. N.; Walker, E. A.; Stewart, P. M. (2005). "Minireview: Hexose-6-phosphate dehydrogenase and redox control of 11{beta ... The oxidative or reductive capacity of the enzyme is regulated by NADH produced by hexose-6-phosphate dehydrogenase (H6PD). ...
Diose
Triose Tetrose Pentose Hexose Heptose Mathews, Christopher K.; Van Holde, Kensal Edward; Ahern, Kevin G. (2000). Biochemistry ( ...
Idose
... is a hexose, a six carbon monosaccharide. It has an aldehyde group and is an aldose. It is not found in nature, but its ...
Glucose transporter
Diderich JA, Schuurmans JM, Van Gaalen MC, Kruckeberg AL, Van Dam K (December 2001). "Functional analysis of the hexose ... GLUT proteins transport glucose and related hexoses according to a model of alternate conformation, which predicts that the ... Boles E, Hollenberg CP (August 1997). "The molecular genetics of hexose transport in yeasts". FEMS Microbiology Reviews. 21 (1 ...
Aerobic fermentation
Hexose transporters (HXT) are a group of proteins that are largely responsible for the uptake of glucose in yeast. In S. ... Lin, Zhenguo; Li, Wen-Hsiung (2011-01-01). "Expansion of Hexose Transporter Genes Was Associated with the Evolution of Aerobic ... There is a significant positive correlation between the number of hexose transporter genes and the efficiency of ethanol ... Boles, E.; Hollenberg, C. P. (1997-08-01). "The molecular genetics of hexose transport in yeasts". FEMS Microbiology Reviews. ...
Position-specific isotope analysis
"Intramolecular 13C pattern in hexoses from autotrophic and heterotrophic C3 plant tissues". Proceedings of the National Academy ...
Artturi Ilmari Virtanen
His research started with work on the phosphorylation of hexoses in 1924. He was able to show that phosphorylation is the first ...
African Journal of Biochemistry Research - altered plasma hexose sugar metabolism in sickle cell anaemia
nbsp; Key words: Hexose, anergy, glucose, fructose, spermatozoa, energy metabolism, metabolic ... nbsp; Key words: Hexose, anergy, glucose, fructose, spermatozoa, energy metabolism, metabolic ... nbsp; Theoretical suggestion that the metabolism and plasma levels of some hexoses (glucose and fructose) in sickle cell ... nbsp; Theoretical suggestion that the metabolism and plasma levels of some hexoses (glucose and fructose) in sickle cell ...
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Hexose-6-phosphate Dehydrogenase Modulates 11beta-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7beta...
Hexose-6-phosphate Dehydrogenase Modulates 11beta-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7beta ... Hexose-6-phosphate Dehydrogenase Modulates 11beta-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7beta ... whereas it predominantly catalyzes the reduction of cortisone to cortisol in intact cells that also express hexose-6-phosphate ...
Active Hexose Correlated Compound Usage | FoundHealth
Understand the usages of Active Hexose Correlated Compound in various health conditions. Explore other smart treatment options ... 0 people have tried Active Hexose Correlated Compound 0 people have prescribed Active Hexose Correlated Compound ... Tried or prescribed Active Hexose Correlated Compound? Share your experience. Have you? Ive Tried it 0 ... Supplementation with active hexose correlated compound increases the innate immune response of young mice to primary influenza ...
Hexose + C13H19O (isomer of 1061) Mass Spectrum
Hexose + C13H19O (isomer of 1061) with the InChIKey SZOPSAFLRCYJCX-UHFFFAOYSA-N. ... CH$NAME: Hexose + C13H19O (isomer of 1061). CH$COMPOUND_CLASS: Terpene glycosides. CH$FORMULA: C19H30O7. CH$EXACT_MASS: 370.442 ... RECORD_TITLE: Hexose + C13H19O (isomer of 1061); LC-ESI-QTOF; MS2. DATE: 2019.03.28. AUTHORS: Tetsuya Mori, Center for ...
AHCC - Active Hexose Correlated Compound | Olympian Labs
AHCC Active Hexose Correlated Compound made from medicinal mushrooms containing bioactive hexose molecules to support Optimal ... AHCC (Active Hexose Correlated Compound) is a natural substance made from medicinal mushrooms containing bioactive, low ... molecular weight hexose molecules. At Tokyo University researchers found that AHCC supplementation clearly affects the strength ...
Hexose transporter family | Transporters | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY
Hexose transporter family in the IUPHAR/BPS Guide to PHARMACOLOGY. ... Hexose transporter family C. Unless otherwise stated all data on this page refer to the human proteins. Gene information is ... Detailed characterisation of members of the hexose transporter family is limited to SGLT1, 2 and 3, which are all inhibited in ... Hexose transporter family. Accessed on 28/11/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ ...
What Can Active Hexose Corresponded Compound (AHCC) Aid In?
Active Hexose Corresponded Compound (AHCC) items are a concentrate of the mushroom root the mycelia ... Active hexose corresponded compound (AHCC) is a matured mushroom separate that is industrially accessible and advanced for ... More up to date to Western development, Active Hexose Corresponded Compound (AHCC) items are a concentrate of the mushroom root ...
Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness -...
Hexose-6 phosphate dehydrogenase (H6PDH) is a microsomal enzyme whose activity regulates corticosteroid metabolism in the liver ... association study in 854 members of 224 families to assess the relationship between polymorphisms in the gene coding for hexose ... Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness ... Hexose-6 phosphate dehydrogenase (H6PDH) is a microsomal enzyme whose activity regulates corticosteroid metabolism in the liver ...
Abnormalities of glucose homeostasis and the hypothalamic-pituitary-adrenal axis in mice lacking hexose-6-phosphate...
N2 - Hexose-6-phosphate dehydrogenase (EC 1.1.1.47) catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone ... AB - Hexose-6-phosphate dehydrogenase (EC 1.1.1.47) catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone ... Hexose-6-phosphate dehydrogenase (EC 1.1.1.47) catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone ... abstract = "Hexose-6-phosphate dehydrogenase (EC 1.1.1.47) catalyzes the conversion of glucose 6-phosphate to 6- ...
Table 2 - Environmental Source of Candida dubliniensis - Volume 13, Number 5-May 2007 - Emerging Infectious Diseases journal -...
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Lectin Affinity Chromatography | Semantic Scholar
Metabolites | Free Full-Text | Comparative Metabolomics of Early Development of the Parasitic Plants Phelipanche aegyptiaca and...
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Erythrocyte Morphology on Peripheral Smear
Elizabeth M. Gardner
A short review on SSF - an interesting process option for ethanol production from lignocellulosic feedstocks | Biotechnology...
... straw hydrolyzate can be expected to give final ethanol concentrations close to 40 g L-1 with a yield based on total hexoses ... decreasing the yeast concentration and co-fermentation of both hexoses and pentoses during SSF. Presently, an SSF process for e ... 1. Low- and intermediate-affinity hexose transporters. 2. High-affinity hexose transporters. (Abbreviations: PPP, pentose ... du Preez JC, Bosch M, Prior BA: The fermentation of hexose and pentose sugars by Candida shehatae and Pichia stipitis. Appl ...
Glycosylation of a model proto-RNA nucleobase with non-ribose sugars: implications for the prebiotic synthesis of nucleosides -...
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9781319114633 - Biochemistry: A Short Course by John L. Tymoczko | eCampus.com
Three Molecules of ATP and Two Molecules of NADPH Are Used to Bring Carbon Dioxide to the Level of a Hexose Biological Insight ... 23.1 The Calvin Cycle Synthesizes Hexoses from Carbon Dioxide and Water. Carbon Dioxide Reacts with Ribulose 1,5-bisphosphate ... Hexose Phosphates Are Made from Phosphoglycerate, and Ribulose 1,5-bisphosphate Is Regenerated ...
Carbohydrate Metabolism!
MonophosphateDehydrogenasePentosesGlucoseAHCCTransportersSupplementationSugarsMiceCOMPOUNDNeutralCarbonSugarLevelsIndustrialFoundGlucosePentosesMetabolismTransportersMonosaccharide hexoseOxidationUptakeIntestinalPathwaysCompoundsMonophosphatesPhosphorylationMoleculeDeoxyMushroomAmino acidsMethaneOrganismTransportEthanolProteinActive
Monophosphate5
- Clin Genet 2009, 75 (2), 157-62) of the hexose monophosphate shunt. (justia.com)
- About 90% of glucose metabolism in the body occurs via the glycolytic pathway and the remaining 10% via the hexose monophosphate pathway. (mhmedical.com)
- The hexose monophosphate shunt leads to formation of pentoses and generates NADH. (mhmedical.com)
- Transaldolase deficiency (MIM no. 606003) affects the nonoxidative branch of the hexose monophosphate pathway. (mhmedical.com)
- Phagocytosis-related events, such as enhanced hexose monophosphate shunt activity, H2O2 formation, and nitroblue tetrazolium reduction were also stimulated by LPS. (aai.org)
Dehydrogenase4
- Experiments determining initial rates of enzyme activity revealed that 11beta-HSD1 can catalyze both the reductase and the dehydrogenase reaction in cell lysates, whereas it predominantly catalyzes the reduction of cortisone to cortisol in intact cells that also express hexose-6-phosphate dehydrogenase (H6PDH), which provides cofactor NADPH. (unibas.ch)
- Hexose-6-phosphate dehydrogenase (EC 1.1.1.47) catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone within the lumen of the endoplasmic reticulum, thereby generating reduced nicotinamide adenine dinucleotide phosphate. (elsevier.com)
- Mice with targeted inactivation of hexose-6-phosphate dehydrogenase lack 11β-hydroxysteroid dehydrogenase type 1 reductase activity, whereas dehydrogenase activity (corticosterone to 11- dehydrocorticosterone) is increased. (elsevier.com)
- Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis. (cdc.gov)
Pentoses1
- Significant progress has been made with respect to increasing the substrate loading, decreasing the yeast concentration and co-fermentation of both hexoses and pentoses during SSF. (biomedcentral.com)
Glucose3
- Theoretical suggestion that the metabolism and plasma levels of some hexoses (glucose and fructose) in sickle cell anaemia could be altered was investigated. (academicjournals.org)
- Figure 1 compares the amino acid alanine with the sugar glucose, a hexose. (reasons.org)
- Second, each amino acid has only two reaction sites, the carboxyl carbon and the amino group, while each hexose (e.g., glucose) contains five reaction sites, the glycosidic carbon and four hydroxyl groups. (reasons.org)
AHCC8
- Preventive effect of active hexose correlated compound (AHCC) on the recurrence of postoperative hepatocellular carcinoma. (foundhealth.com)
- The influence of active hexose correlated compound (AHCC) on cisplatin-evoked chemotherapeutic and side effects in tumor-bearing mice. (foundhealth.com)
- AHCC (Active Hexose Correlated Compound) is a natural substance made from medicinal mushrooms containing bioactive, low molecular weight hexose molecules. (olympianlabs.com)
- What Can Active Hexose Corresponded Compound (AHCC) Aid In? (trendhealth.org)
- More up to date to Western development, Active Hexose Corresponded Compound (AHCC) items are a concentrate of the mushroom root-the mycelia-which various clinical examinations have appeared to display a beneficial outcome on human wellbeing. (trendhealth.org)
- Active hexose corresponded compound (AHCC) is a matured mushroom separate that is industrially accessible and advanced for immune help. (trendhealth.org)
- Short-term supplementation with Active Hexose Correlated Compound (AHCC) improves the antibody response to influenza B vaccine Nutr Res. (msu.edu)
- Unlike other AHCC Supplements, AHCC powder, mushroom supplements, mushroom extracts and active hexose correlated compounds, Quality of Life's AHCC's complex is clinically studied. (initng.org)
Transporters1
- Facilitative hexose transporters (GLUTs), with 14 known isoforms to date, GLUT1-GLUT14, transport the oxidized form of vitamin C (dehydroascorbic acid) into the cells. (scielo.cl)
Supplementation1
- Supplementation with active hexose correlated compound increases the innate immune response of young mice to primary influenza infection. (foundhealth.com)
Sugars1
- the other capsular Haemophilus serotypes are composed of hexose rather than pentose sugars. (medscape.com)
Mice1
- Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions. (foundhealth.com)
COMPOUND1
- Tried or prescribed Active Hexose Correlated Compound? (foundhealth.com)
Neutral1
- The agents had low molecular weights and neutral charges, and possibly contained amino-nitrogen and hexose residues. (cdc.gov)
Carbon1
- Since each of these contains six carbon atoms, they are collectively called "hexoses" (hex- for six and -ose for sugar). (thebeveragepeople.com)
Sugar1
- Each hexose sugar has five reactive sites: the glycosidic site (red) and the hydroxyl sites (blue). (reasons.org)
Levels1
- [ 1 ] Increased muscle glycogen content and high levels of hexose monophosphates were noted. (medscape.com)
Industrial1
- Red Star is a robust hexose-fermenting strain used for industrial fuel ethanol fermentations and it was used for comparative purposes. (chalmers.se)
Found1
- Phenolic acids were found mainly as hexose esters. (eurekamag.com)
Glucose9
- Taken together, these results suggest that the defect in glucose uptake and metabolism found in GSD lb patient PMN is due to an impairment in hexose phosphorylation rather than in a reduction in the transmembrane glucose transport activity. (bgu.ac.il)
- Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. (mcw.edu)
- Gluconeogenesis is the pathway by which non-hexose substrates such as amino acids are converted to glucose. (colostate.edu)
- Glucose, the most common monosaccharide has six carbons per molecule, which is called a hexose. (123helpme.com)
- Amos is known for his research into bacterial metabolism and animal and bacterial virology, including the use of bacterial RNA to program higher cell protein synthesis, enzyme inductions, insulin, serum, temperature effects, ribosomes, phosphoproteins, RNA metabolism, as well as glucose starvation and glycerol and hexose metabolism. (harvard.edu)
- C-mannose is modelled as a hexose, Hex (W). O-fucosylation is available as deoxy hexose, dHex (ST), while the O-linked fucose-glucose disaccharide is dHex(1)Hex(1) (ST). All the Unimod glycan definitions were updated in 2015 to take their labile nature into account: most specificities have a neutral loss equal to the modification delta. (matrixscience.com)
- The other missing piece is allowing the loss of a hexose from dHex(1)Hex(1), which models the loss of glucose. (matrixscience.com)
- The Warburg effect describes the high flux of glucose through glycolysis, which converts hexoses to trioses, a source of glycerol for lipid synthesis, ending with pyruvate that is converted to lactate. (aacrjournals.org)
- A hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (uams.edu)
Pentoses4
- Esta enzima é chave na regulação da biossíntese das pentoses e hexoses da parede celular de plantas superiores. (usp.br)
- A relação hexoses/pentoses reduziu em todas as linhagens transgênicas, sendo significativa em três linhagens. (usp.br)
- Wood fractionation of wood to obtain monosaccharides, especially hexoses and pentoses, was studied using ionic liquid (IL) based pre-treatment. (abo.fi)
- Hexoses and pentoses could be detected. (abo.fi)
Metabolism3
- We adapted our barcoding methodology to facilitate multiplexed validation of bacterial fitness determinants identified with transposon mutagenesis and confirmed the importance of bacterial hexose metabolism and cell envelope homeostasis pathways for organ-specific pathogen survival. (elifesciences.org)
- Resumen en inglés From 1960 to the end of the XX century, efforts from different laboratories were done to understand the regulation of eicosanoids biosynthesis and metabolism. (worldwidescience.org)
- Expression of a bacterial xylose isomerase in potato tubers results in an altered hexose composition and a consequent induction of metabolism. (mpg.de)
Transporters5
- ABC Transporters Required for Hexose Uptake by Clostridium phytofermentans. (sigmaaldrich.com)
- Here, we use functional genomic, genetic, and biophysical approaches to reveal how Clostridium (Lachnoclostridium) phytofermentans, a model bacterium that ferments lignocellulosic biomass, uptakes plant hexoses using highly specific, nonredundant ATP-binding cassette (ABC) transporters. (sigmaaldrich.com)
- Inactivation of these genes reveals that individual ABC transporters are required for uptake of hexoses and hexo-oligosaccharides and that distinct ABC transporters are used for oligosaccharides versus their constituent monomers. (sigmaaldrich.com)
- 9. Expression and function of hexose transporters GLUT1, GLUT2, and GLUT5 in breast cancer-effects of hypoxia. (nih.gov)
- Dr. W. Ian Lipkin wrote, 'Our data show that at least some children with autism have a distinct intestinal profile that is linked to deficient expression of disaccharides, and hexose transporters, potentially promoting maldigestion, malabsorption, and multicomponent, compositional dysbiosis. (ageofautism.com)
Monosaccharide hexose1
- D-Mannose is a monosaccharide hexose sugar, naturally found in some trees, berries and fruits, such as cranberry. (baar.com)
Oxidation1
- Hexose oxidation by rat heart homogenate of a multienzyme system. (microbiologyresearch.org)
Uptake3
- These mechanisms used by Clostridia to uptake plant hexoses are key to understanding soil and intestinal microbiomes and to engineer strains for industrial transformation of lignocellulose.IMPORTANCE Plant-fermenting Clostridia are anaerobic bacteria that recycle plant matter in soil and promote human health by fermenting dietary fiber in the intestine. (sigmaaldrich.com)
- Because 2-DOG is phosphorylated within the cell, its uptake rate reflects hexose transport as long as phosphorylation is not rate-limiting. (bgu.ac.il)
- In 1957, Nirenberg earned a Ph.D. in biological chemistry by writing a dissertation on the uptake of hexose, a type of sugar, by tumor cells. (nih.gov)
Intestinal1
- GLP-2 also inhibits gastric acid secretion and emptying and up-regulates intestinal hexose transport. (nih.gov)
Pathways1
- Dissociation of signaling pathways for insulin- and contraction-activated hexose transport. (vanderbilt.edu)
Compounds1
- It can achieve either 'class separations' (e.g. delivering all hexose monophosphates into a single pool) or the resolution of different compounds within a given class (e.g. (ed.ac.uk)
Monophosphates1
- [ 1 ] Increased muscle glycogen content and high levels of hexose monophosphates were noted. (medscape.com)
Phosphorylation1
- Metabolic profiling of transgenic tomato plants overexpressing hexokinase reveals that the influence of hexose phosphorylation diminishes during fruit development. (mpg.de)
Molecule2
- A hexose is a monosaccharide whose molecule contains six carbon atoms. (ochempal.org)
- They have six atoms of carbon in each molecule and are therefore called hexoses. (lexico.com)
Deoxy1
- Acylation of 6-deoxy-L-hexoses. (unipv.it)
Mushroom1
- Time Health Active Hexose Correlated Compound is an alpha-glucan rich nutritional food supplement produced from a special mixed mushroom broad-spectrum formula like no other on the market today. (timehealth.co.uk)
Amino acids1
- The analyses were performed with the BIOCRATES AbsoluteIDQ™ targeted metabolomics technology, including acylcarnitines, amino acids, glycerophospholipids, sphingolipids and hexose in 100 healthy individuals from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study who had provided two fasting blood samples 4 months apart. (technologynetworks.com)
Methane1
- Sulfate groups may attach to the hexose ring via an oxygen, amino, aminoacetyl, or methane link. (perfusion.com)
Organism1
- Fate of several hexoses in the animal organism and their relation to the formation of glycogen. (nih.gov)
Transport1
- Furthermore, we revealed that the amino acid residue Q341 and W455, which were located in the middle of the transport channel closer to the exit, are the sterically hindered barrier to levoglucosan transportation in Gal2p, a hexose transporter. (biomedcentral.com)
Ethanol1
- Co-fermentation of succinic acid and ethanol from sugarcane bagasse based on full hexose and pentose utilization and car. (mysciencework.com)
Protein1
- The LPS was composed of 21.7% hexose, 9.1% hexosamine, 10.3% fatty acid, 0.5% protein, 2.5% phosphorus, 4.3% 2‐keto‐3‐deoxyoctonate(KDO) and 2.3% heptose. (elsevier.com)
Active3
- View basket "Active Hexose Correlated Compound High Strength Immune Support" has been added to your basket. (timehealth.co.uk)
- Our High Strength Active Hexose Correlated Compound contains a potent mix of specially selected mushrooms to boost the immune system. (timehealth.co.uk)
- Why is your Active Hexose Correlated Compound so much cheaper than the branded version? (timehealth.co.uk)