Herpes Genitalis
Genital Diseases, Male
Herpes Simplex
Genital Diseases, Female
Ointments
Simplexvirus
Herpes Zoster
Herpesvirus 1, Human
Herpes Labialis
Association of major histocompatibility complex determinants with the development of symptomatic and asymptomatic genital herpes simplex virus type 2 infections. (1/910)
The clinical spectrum of herpes simplex virus (HSV) infections, ranging from asymptomatic to frequently distressing outbreaks, suggests that there may be immunologic determinants of disease severity that are associated with human leukocyte antigen (HLA) expression. A controlled, prospective study identified several major histocompatibility complex (MHC) class I and II antigens whose frequencies are associated with HSV-2 infection or with frequent symptomatic genital recurrences. Previous studies were hampered by the inability to serologically identify patients with asymptomatic HSV-2 infection. Clinical evaluation and Western blot assay were used to identify 3 subject cohorts: 1 with no prior HSV infections, 1 with HSV-2 antibodies but no recognized symptoms, and 1 with HSV-2 antibodies and frequent genital recurrences. Statistical comparisons of HLA frequencies among these cohorts showed associations of HLA-B27 and -Cw2 with symptomatic disease. Also, HLA-Cw4 was significantly associated with HSV-2 infection. These associations indicate that immunologic factors linked to the MHC influence the risk of HSV-2 infection and disease expression. (+info)Control of STDs--the role of prophylactic vaccines against herpes simplex virus. (2/910)
OBJECTIVES: To summarise the current status of genital herpes simplex virus (HSV) vaccine development and provide a discussion of the potential benefits and limitations of genital herpes vaccines. METHODS: Literature review. RESULTS: Genital herpes simplex virus infection has a complex pathogenesis that has contributed to it becoming a serious worldwide problem. In an attempt to control the problem five different types of genital herpes vaccines have been developed. These include inactivated virion derived vaccines, adjuvanted subunit vaccines, vectored vaccines, replication limited live viral vaccines, genetically attenuated live viral vaccines, and nucleic acid vaccines. While available commercially in some parts of the world, inactivated virion derived vaccines have not been proved effective. Of the others, adjuvanted subunit vaccines, replication limited live viral vaccines, and nucleic acid vaccines are currently in clinical trials and vectored vaccines and genetically attenuated live viral vaccines are in preclinical development. CONCLUSION: With regard to HSV vaccines in general, it is reasonable to expect that the newer vaccines may protect the individual from developing symptomatic genital herpes but may not protect against asymptomatic viral infection. With widespread use HSV vaccines might help to prevent the spread of genital herpes. (+info)Comparison between virus isolation method, Papanicolaou stain, immunoperoxidase stain and polymerase chain reaction in the diagnosis of genital herpes. (3/910)
Papanicolaou (Pap) stain, immunoperoxidase (IP) stain and polymerase chain reaction (PCR) were evaluated against the virus isolation method for their sensitivity and specificity in the diagnosis of herpes simplex virus (HSV) infection in 96 women who were suspected of genital herpes. The result showed that the sensitivity of PCR, IP and Pap stain was 100, 92.0 and 62.7%, respectively, while the specificity was 76.2, 66.7 and 81.0%, respectively. PCR was even more sensitive than the virus isolation technique. As Pap stain is the technique routinely performed for diagnosing genital herpes in most of the hospitals in Thailand, its low sensitivity should be taken into consideration. Based on the investigation by all four techniques together, HSV infection was diagnosed in 91.6% of the cases suspected of genital herpes which reflected higher precision of the clinical diagnosis over Pap stain. (+info)Development of a high-throughput quantitative assay for detecting herpes simplex virus DNA in clinical samples. (4/910)
We have developed a high-throughput, semiautomated, quantitative fluorescence-based PCR assay to detect and type herpes simplex virus (HSV) DNA in clinical samples. The detection assay, which uses primers to the type-common region of HSV glycoprotein B (gB), was linear from <10 to 10(8) copies of HSV DNA/20 microl of sample. Among duplicate samples in reproducibility runs, the assay showed less than 5% variability. We compared the fluorescence-based PCR assay with culture and gel-based liquid hybridization system with 335 genital tract specimens from HSV type 2 (HSV-2)-seropositive persons attending a research clinic and 380 consecutive cerebrospinal fluid (CSF) samples submitted to a diagnostic virology laboratory. Among the 162 culture-positive genital tract specimens, TaqMan PCR was positive for 157 (97%) specimens, whereas the quantitative-competitive PCR was positive for 144 (89%) specimens. Comparisons of the mean titer of HSV DNA detected by the two assays revealed that the mean titer detected by the gel-based system was slightly higher (median, 1 log). These differences in titers were in part related to the fivefold difference in the amount of HSV DNA used in the amplicon standards with the two assays. Among the 380 CSF samples, 42 were positive by both assays, 13 were positive only by the assay with the agarose gel, and 3 were positive only by the assay with the fluorescent probe. To define the subtype of HSV DNA detected in the screening assay, we also designed one set of primers which amplifies the gG regions of both types of HSV and probes which are specific to either HSV-1 (gG1) or HSV-2 (gG2). These probes were labeled with different fluorescent dyes (6-carboxyfluorescein for gG2 and 6-hexachlorofluorescein for gG1) to enable detection in a single PCR. In mixing experiments the probes discriminated the correct subtype in mixtures with up to a 7-log-higher concentration of the opposite subtype. The PCR typing results showed 100% concordance with the results obtained by assays with monoclonal antibodies against HSV-1 or HSV-2. Thus, while the real-time PCR is slightly less sensitive than the gel-based liquid hybridization system, the high throughput, the lack of contamination during processing, the better reproducibility, and the better ability to type the isolates rapidly make the real-time PCR a valuable tool for clinical investigation and diagnosis of HSV infection. (+info)Seroprevalence of herpes simplex virus-type 2 in African-American college women. (5/910)
This study examines the relationship between sexual behaviors and prevalence of herpes simplex virus-type 2 (HSV-2) among African-American college women. Subjects (n = 138) were recruited randomly from a state university to participate in a study regarding sexual attitudes and behaviors and to have their blood drawn for type-specific HSV seroprevalence. Sera were analyzed for 96 college women with a mean age of 21 years. Of the 96 women, 29 (30%) were HSV-2 seropositive. The results of this study revealed that a history of sexually transmitted disease was predictive of HSV-2 infection. Number of lifetime partners, however, was not related to HSV-2 seropositivity. Four (31%) of the 13 women who reported only one lifetime partner were seropositive. These findings indicate that for young African-American college women, the risk of being infected with HSV-2 is high even with only one lifetime partner. Behavioral strategies focused on decreasing the number of sexual partners are not likely to be sufficient in preventing the spread of HSV-2 infection among young African-American women. The development and use of alternative approaches to prevent the spread of HSV-2 among young African Americans should be considered. (+info)The epidemiology of neonatal herpes simplex virus infections in California from 1985 to 1995. (6/910)
Comprehensive hospital discharge data completed by the California Office of Statewide Health Planning and Development was used to determine whether the proportion of infants +info)The topical microbicide PRO 2000 protects against genital herpes infection in a mouse model. (7/910)
Vaginal gel formulations containing the naphthalene sulfonate polymer PRO 2000 are being developed as topical microbicides to protect against infection with sexually transmitted disease (STD) pathogens. A mouse model was used to determine whether PRO 2000 could protect against genital herpes in vivo. Animals received a single intravaginal application of 15 microL of a 10% PRO 2000 aqueous solution or a 4.0% or 0.5% PRO 2000 vaginal gel formulation 20 s prior to intravaginal challenge with 4.0 log10 pfu of herpes simplex virus type 2. Treatment with the 4.0% gel provided complete protection against infection; treatment with the 0.5% gel or 10% solution provided 81% and 80% protection, respectively. Furthermore, the 4% gel provided significant protection even when viral challenge was delayed until 60 min after treatment. This is the first report to show that PRO 2000 can protect against infection with an STD pathogen in vivo. (+info)Immunization against genital herpes with a vaccine virus that has defects in productive and latent infection. (8/910)
An effective vaccine for genital herpes has been difficult to achieve because of the limited efficacy of subunit vaccines and the safety concerns about live viruses. As an alternative approach, mutant herpes simplex virus strains that are replication-defective can induce protective immunity. To increase the level of safety and to prove that replication was not needed for immunization, we constructed a mutant herpes simplex virus 2 strain containing two deletion mutations, each of which eliminated viral replication. The double-mutant virus induces protective immunity that can reduce acute viral shedding and latent infection in a mouse genital model, but importantly, the double-mutant virus shows a phenotypic defect in latent infection. This herpes vaccine strain, which is immunogenic but has defects in both productive and latent infection, provides a paradigm for the design of vaccines and vaccine vectors for other sexually transmitted diseases, such as AIDS. (+info)Herpes genitalis is a sexually transmitted infection caused by the herpes simplex virus (HSV), specifically HSV-2, and occasionally HSV-1. It primarily affects the genital area, but can also involve the anal region, thighs, and buttocks. The infection presents as painful fluid-filled blisters or lesions that may be accompanied by symptoms such as itching, tingling, or burning sensations in the affected area. After the initial outbreak, the virus remains dormant in the body and can reactivate periodically, causing recurrent episodes of genital herpes. It's important to note that while there is no cure for herpes genitalis, antiviral medications can help manage symptoms and reduce transmission risks.
Genital diseases in males refer to various medical conditions that affect the male reproductive and urinary systems, including the penis, testicles, epididymis, vas deferens, seminal vesicles, prostate, and urethra. These conditions can be infectious, inflammatory, degenerative, or neoplastic (cancerous) in nature. Some common examples of male genital diseases include:
1. Balanitis: Inflammation of the foreskin and glans penis, often caused by infection, irritants, or poor hygiene.
2. Prostatitis: Inflammation of the prostate gland, which can be acute or chronic, bacterial or non-bacterial in origin.
3. Epididymitis: Inflammation of the epididymis, a coiled tube at the back of the testicle that stores and carries sperm. It is often caused by infection.
4. Orchitis: Inflammation of the testicle, usually resulting from infection or autoimmune disorders.
5. Testicular torsion: A surgical emergency characterized by twisting of the spermatic cord, leading to reduced blood flow and potential tissue damage in the testicle.
6. Varicocele: Dilated veins in the scrotum that can cause pain, discomfort, or fertility issues.
7. Peyronie's disease: A connective tissue disorder causing scarring and curvature of the penis during erections.
8. Penile cancer: Malignant growths on the penis, often squamous cell carcinomas, which can spread to other parts of the body if left untreated.
9. Benign prostatic hyperplasia (BPH): Non-cancerous enlargement of the prostate gland that can cause lower urinary tract symptoms such as difficulty initiating or maintaining a steady stream of urine.
10. Sexually transmitted infections (STIs): Infectious diseases, like chlamydia, gonorrhea, syphilis, and human papillomavirus (HPV), that can be transmitted through sexual contact and affect the male genital region.
Herpes Simplex is a viral infection caused by the Herpes Simplex Virus (HSV). There are two types of HSV: HSV-1 and HSV-2. Both types can cause sores or blisters on the skin or mucous membranes, but HSV-1 is typically associated with oral herpes (cold sores) and HSV-2 is usually linked to genital herpes. However, either type can infect any area of the body. The virus remains in the body for life and can reactivate periodically, causing recurrent outbreaks of lesions or blisters. It is transmitted through direct contact with infected skin or mucous membranes, such as during kissing or sexual activity.
Genital diseases in females refer to various medical conditions that affect the female reproductive system, including the vulva, vagina, cervix, uterus, and ovaries. These conditions can be caused by bacterial, viral, or fungal infections, hormonal imbalances, or structural abnormalities. Some common examples of genital diseases in females include bacterial vaginosis, yeast infections, sexually transmitted infections (STIs) such as chlamydia, gonorrhea, and human papillomavirus (HPV), pelvic inflammatory disease (PID), endometriosis, uterine fibroids, ovarian cysts, and vulvar or vaginal cancer. Symptoms of genital diseases in females can vary widely depending on the specific condition but may include abnormal vaginal discharge, pain or discomfort during sex, irregular menstrual bleeding, painful urination, and pelvic pain. It is important for women to receive regular gynecological care and screenings to detect and treat genital diseases early and prevent complications.
An ointment is a semi-solid preparation, typically composed of a mixture of medicinal substance with a base, which is usually greasy or oily. The purpose of the base is to act as a vehicle for the active ingredient and allow it to be applied smoothly and evenly to the skin or mucous membranes.
Ointments are commonly used in dermatology to treat various skin conditions such as eczema, psoriasis, rashes, burns, and wounds. They can also be used to deliver medication for localized pain relief, muscle relaxation, and anti-inflammatory or antibiotic effects.
The base of an ointment may consist of various ingredients, including petrolatum, lanolin, mineral oil, beeswax, or a combination of these. The choice of the base depends on the desired properties such as consistency, spreadability, and stability, as well as the intended route of administration and the specific therapeutic goals.
Simplexvirus is a genus of viruses in the family Herpesviridae, subfamily Alphaherpesvirinae. This genus contains two species: Human alphaherpesvirus 1 (also known as HSV-1 or herpes simplex virus type 1) and Human alphaherpesvirus 2 (also known as HSV-2 or herpes simplex virus type 2). These viruses are responsible for causing various medical conditions, most commonly oral and genital herpes. They are characterized by their ability to establish lifelong latency in the nervous system and reactivate periodically to cause recurrent symptoms.
Herpes zoster, also known as shingles, is a viral infection that causes a painful rash. It's caused by the varicella-zoster virus, which also causes chickenpox. After you recover from chickenpox, the virus lies dormant in your nerve cells and can reactivate later in life as herpes zoster.
The hallmark symptom of herpes zoster is a unilateral, vesicular rash that occurs in a dermatomal distribution, which means it follows the path of a specific nerve. The rash usually affects one side of the body and can wrap around either the left or right side of your torso.
Before the rash appears, you may experience symptoms such as pain, tingling, or itching in the area where the rash will develop. Other possible symptoms include fever, headache, fatigue, and muscle weakness. The rash typically scabs over and heals within two to four weeks, but some people may continue to experience pain in the affected area for months or even years after the rash has healed. This is known as postherpetic neuralgia (PHN).
Herpes zoster is most common in older adults and people with weakened immune systems, although anyone who has had chickenpox can develop the condition. It's important to seek medical attention if you suspect you have herpes zoster, as early treatment with antiviral medications can help reduce the severity and duration of the rash and lower your risk of developing complications such as PHN.
Recurrence, in a medical context, refers to the return of symptoms or signs of a disease after a period of improvement or remission. It indicates that the condition has not been fully eradicated and may require further treatment. Recurrence is often used to describe situations where a disease such as cancer comes back after initial treatment, but it can also apply to other medical conditions. The likelihood of recurrence varies depending on the type of disease and individual patient factors.
Medical Definition of "Herpesvirus 1, Human" (also known as Human Herpesvirus 1 or HHV-1):
Herpesvirus 1, Human is a type of herpesvirus that primarily causes infection in humans. It is also commonly referred to as human herpesvirus 1 (HHV-1) or oral herpes. This virus is highly contagious and can be transmitted through direct contact with infected saliva, skin, or mucous membranes.
After initial infection, the virus typically remains dormant in the body's nerve cells and may reactivate later, causing recurrent symptoms. The most common manifestation of HHV-1 infection is oral herpes, characterized by cold sores or fever blisters around the mouth and lips. In some cases, HHV-1 can also cause other conditions such as encephalitis (inflammation of the brain) and keratitis (inflammation of the eye's cornea).
There is no cure for HHV-1 infection, but antiviral medications can help manage symptoms and reduce the severity and frequency of recurrent outbreaks.
Herpes labialis, also known as cold sores or fever blisters, is a common viral infection caused by the herpes simplex virus type 1 (HSV-1). It typically affects the lips, mouth, and surrounding skin. The infection causes small, painful, fluid-filled blisters that can be accompanied by symptoms such as tingling, burning, or itching in the area before the blisters appear. After the blisters break, they leave behind painful ulcers that eventually crust over and heal within 2-3 weeks.
The virus is highly contagious and can spread through direct contact with infected saliva, skin lesions, or objects contaminated with the virus. Once a person becomes infected with HSV-1, the virus remains dormant in the nervous system and can reactivate periodically due to various triggers like stress, fatigue, illness, or sun exposure, leading to recurrent outbreaks of herpes labialis.
Medical Definition of "Herpesvirus 2, Human" (also known as Human Herpesvirus 2 or HHV-2):
Herpesvirus 2, Human is a double-stranded DNA virus that belongs to the Herpesviridae family. It is one of the eight herpesviruses known to infect humans. HHV-2 is the primary cause of genital herpes, a sexually transmitted infection (STI) that affects the mucosal surfaces and skin around the genitals, rectum, or mouth.
The virus is typically transmitted through sexual contact with an infected person, and it can also be spread from mother to child during childbirth if the mother has active genital lesions. After initial infection, HHV-2 establishes latency in the sacral ganglia (a collection of nerve cells at the base of the spine) and may reactivate periodically, leading to recurrent outbreaks of genital herpes.
During both primary and recurrent infections, HHV-2 can cause painful blisters or ulcers on the skin or mucous membranes, as well as flu-like symptoms such as fever, swollen lymph nodes, and body aches. While there is no cure for genital herpes, antiviral medications can help manage symptoms, reduce outbreak frequency, and lower the risk of transmission to sexual partners.
It's important to note that HHV-2 infection can sometimes be asymptomatic or cause mild symptoms that go unnoticed, making it difficult to determine the exact prevalence of the virus in the population. According to the World Health Organization (WHO), an estimated 491 million people worldwide aged 15 years and older have HSV-2 infection, with a higher prevalence in women than men.
Susceptibility and severity of infections in pregnancy
Zinc
Vaginal disease
Cervicitis
Herpes simplex
Vulvar cancer
Irritation
Genital herpes
EGW
List of MeSH codes (C02)
List of causes of genital pain
Butylated hydroxytoluene
Non-gonococcal urethritis
Sex Ed (The Office)
Urethritis
List of model organisms
List of skin conditions
Reproductive system disease
Lissencephaly
Vaginal discharge
Equine venereal disease
Women's health
Sexually transmitted infection
Non-penetrative sex
Comparative genomics
Vulvitis
Dyspareunia
Dexamethasone
Bet hedging (biology)
Circumcision
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Labialis5
- and herpes labialis (cold sores). (rxlist.com)
- VALTREX is indicated for treatment of cold sores (herpes labialis). (rxlist.com)
- Treatment of herpes labialis and herpes genitalis generally consists of episodic courses of oral acyclovir, valacyclovir, and famciclovir. (medscape.com)
- The usual cause of oral herpes (herpes labialis), which are commonly called cold sores or fever blisters. (adam.com)
- HSV-1 causes both primary and recurrent disease in the form of gingivostomatitis, keratoconjunctivitis, encephalitis, herpetic whitlow, herpes labialis, and herpes gladiatorum. (medscape.com)
Infection11
- Infection of the genitals (GENITALIA) with HERPES SIMPLEX VIRUS in either the males or the females. (childrensmercy.org)
- Genital herpes is a sexually transmitted infection (STI). (epnet.com)
- The infection is caused by the herpes simplex virus. (epnet.com)
- In view of the different biological behavior of the two types of herpes simplex virus (HSV-1 and HSV-2) that may cause genital infection, it is important to identify the virus strain carried as a means of prognosticating evolution of the disease. (paho.org)
- This article reports on the prevalence of genital herpes infection in a sample of 635 female university students who were seen at the Gynecology Center of the University of Chile Student Medical Service. (paho.org)
- Primary herpes simplex infection, when occurring in pregnant women, has an increased risk of dissemination and hepatitis, an otherwise rare complication in immunocompetent adults, particularly during the third trimester. (wikipedia.org)
- I have been tested negative for herpes and any significant bacterial infection. (ndtv.com)
- Most new cases of genital herpes infection do not cause symptoms, and many people infected with HSV-2 are unaware that they have genital herpes. (adam.com)
- This image displays small blisters of a herpes infection (toward the bottom of the picture). (skinsight.com)
- Herpes simplex infection of the genitals, or genital herpes, is a common recurrent skin condition associated with infection by the herpes simplex virus (HSV). (skinsight.com)
- A cell culture positive for herpes simplex virus (HSV) implies probable active infection. (medscape.com)
Zoster3
- Acyclovir is a synthetic purine nucleoside analogue with in vitro and in vivo inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2) and varicella-zoster virus (VZV). (nih.gov)
- Other viruses in this group include the varicella-zoster virus (VZV, also known as herpes zoster, the virus responsible for shingles and chickenpox), the cytomegalovirus (CMV), and the Epstein-Barr virus (EBV). (adam.com)
- Herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2) cause oral and genital herpes, and varicella-zoster virus causes chickenpox in children and shingles later in life. (lifeextension.com)
Chlamydia2
- Patients should be tested for other sexually transmitted infections, including Chlamydia trachomatis , HIV, syphilis , Mycoplasma genitalium , and herpes simplex virus. (medscape.com)
- The most common cause of nongonococcal urethritis (NGU) is Chlamydia trachomatis (15-40% of cases), followed by Mycoplasma genitalium (15-20% of cases). (medscape.com)
Mycoplasma genitalium1
- Persons should be informed about all the tests for STIs they are receiving and notified about tests for common STIs (e.g., genital herpes, trichomoniasis, Mycoplasma genitalium , and HPV) that are available but not being performed and reasons why they are not always indicated. (cdc.gov)
External genitalia1
- Herpes simplex virus (HSV) usually causes vesicular rash of the oropharyngeal area or external genitalia. (medscape.com)
Blisters9
- Do not have oral, anal, or genital sex with a person who has herpes blisters. (epnet.com)
- The herpes simplex virus may manifest as itching and burning blisters and sores located in the genital area. (tommonte.com)
- The first signs are a tingling sensation in the affected areas (genitalia, buttocks, and thighs), and groups of small red bumps that develop into blisters. (adam.com)
- This image displays a grouping of blisters on the buttocks in a patient with herpes simplex. (skinsight.com)
- As displayed in this image, herpes outbreaks often consist of blisters closely spaced together, sometimes with subtle blistering and more redness than fluid. (skinsight.com)
- Patients with herpes simplex of the genitals typically experience early symptoms of itching and/or burning of the skin, and then blisters develop over days, which crust, scab, and resolve in about two weeks. (skinsight.com)
- This image displays blisters and swelling on the labia due to the herpes simplex virus. (skinsight.com)
- This image displays grouped blisters of fluid-filled lesions typical of early stages of herpes. (skinsight.com)
- Associated topics: herpes,cold-sores-/-fever-blisters - "The presence of beta-caryophyllene in many essential oils might contribute strongly to their antiviral ability. (oil-testimonials.com)
Outbreaks5
- Symptoms of herpes are called outbreaks. (medlineplus.gov)
- Flu-like symptoms are common during initial outbreaks of genital herpes. (adam.com)
- Several natural ingredients that may help ease the symptoms of herpes and shingles will also be discussed, and important lifestyle and dietary considerations that can help prevent outbreaks will be examined as well. (lifeextension.com)
- Although there is no effective cure for herpes virus infections, several natural interventions may help reduce the frequency of outbreaks. (lifeextension.com)
- Acyclovir Medication can also be utilized to treat outbreaks of Herpes Genitalis. (acyclovir400mg.com)
Ulcers3
- This image displays large erosions and ulcers due to the herpes simplex virus on the penis on an immunocompromised patient. (skinsight.com)
- a monogamous, HIV-negative office worker and an HIV positive widow, sexually inactive since 5 years, presented with multiple, small shallow genital ulcers with excruciating pain simulating herpes genitalis. (bmj.com)
- other sexually transmitted infections enhance the sexual transmission of HIV: genital herpes specifically, and genital ulcers in general, increase the transmission of HIV 50-300-fold per episode of unprotected sexual intercourse. (who.int)
Recurrences3
- Also, recurrences of herpes genitalis increase in frequency during pregnancy. (wikipedia.org)
- The treatment of herpes simplex virus (HSV) infections depends on multiple factors, including the location and severity of the disease, immune status, pregnancy, primary or recurrent disease, and frequency of recurrences. (medscape.com)
- Genital herpes is a chronic disease characterized by intermittent recurrences. (medscape.com)
Encephalitis1
- FDA approved this drug to treat genital herpes and HSV encephalitis. (acyclovir400mg.com)
Immunocompetent3
- VALTREX is indicated for treatment of the initial episode of genital herpes in immunocompetent adults. (rxlist.com)
- VALTREX is indicated for chronic suppressive therapy of recurrent episodes of genital herpes in immunocompetent and in HIV -1-infected adults. (rxlist.com)
- The efficacy and safety of VALTREX for the suppression of genital herpes beyond 1 year in immunocompetent patients and beyond 6 months in HIV-1-infected patients have not been established. (rxlist.com)
Herpesvirus1
- Twenty-four strains of Herpesvirus hominis (HVH) were tested for their ability to produce large focal necrotic lesions in the liver of mice inoculated intraperitoneally with herpes virus. (microbiologyresearch.org)
Viruses12
- Herpes simplex viruses (HSVs) type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent in the human population, and the infections they produce are lifelong with frequent reactivations throughout life. (frontiersin.org)
- Serological comparison of the herpes viruses. (microbiologyresearch.org)
- Acyclovir Sodium Injection is a synthetic nucleoside analogue, active against herpes viruses. (nih.gov)
- The quantitative relationship between the in vitro susceptibility of herpes viruses to antivirals and the clinical response to therapy has not been established in humans, and virus sensitivity testing has not been standardized. (nih.gov)
- HSV is part of a group of 8 viruses in the Herpes virus family that can cause human disease. (adam.com)
- There are many other strains of herpes viruses that can infect various animals. (adam.com)
- Herpes viruses differ in many ways, but the viruses share certain characteristics. (adam.com)
- This refers to the unique characteristic pattern of all herpes viruses to creep along local nerve pathways to the nerve clusters at the end, where they remain in an inactive (dormant) state for variable periods of time. (adam.com)
- Herpes simplex virus 1 (HSV-1) and HSV-2 are large, double-stranded DNA viruses that cause lifelong persistent infections characterized by periods of quiescence and recurrent disease. (emmes.com)
- Herpes and shingles are both caused by members of the Herpesviridae family of viruses, which can establish latent infections that remain dormant before reactivating at a later time under certain conditions. (lifeextension.com)
- In this protocol, you will learn about the viruses that cause herpes and shingles, and how these infections are conventionally treated. (lifeextension.com)
- Suppression of cellular immunity results in reactivation, spread, and severe illness in diseases caused by herpes viruses. (medscape.com)
Buttocks1
- HSV-1 is the most common cause of infections around the mouth, lips, nose, and face, although HSV-2 can also be a cause, and HSV-2 more commonly causes lesions on the genitals and buttocks (sometimes called sacral herpes). (skinsight.com)
Acyclovir6
- Foscarnet is also used to treat herpes simplex virus (HSV) that is resistant to the antiviral acyclovir. (rxwiki.com)
- Foscarnet is also used to treat herpes simplex virus (HSV) of the mucous membranes that is resistant to the antiviral acyclovir in patients whose immune system is not working properly such as patients who have acquired immunodeficiency syndrome (AIDS) or who have received an organ transplant. (rxwiki.com)
- In vitro , acyclovir triphosphate stops replication of herpes viral DNA. (nih.gov)
- Babies born to mothers infected with genital herpes are often treated with the antiviral drug acyclovir, which can help suppress the virus. (adam.com)
- Antiviral medication (acyclovir, famciclovir, or valacyclovir) is the first line of treatment for both shingles and herpes. (lifeextension.com)
- Acyclovir is not a protection against the transmission of herpes genitalis. (acyclovir400mg.com)
Prevention2
Prevent the spread of herpes2
- Yes there are treatments you and your next or current partner can take/do to prevent the spread of herpes. (fmylife.com)
- Topical microbicides that have antiviral properties, such as tenofovir gel, may prevent the spread of herpes virus. (lifeextension.com)
Strains of herpes1
- Differentiation between type I and type 2 strains of herpes simplex virus by an indirect immunofluorescent technique. (microbiologyresearch.org)
Neonatal herpes1
- HSV-2 cause both primary and recurrent disease in the form of genital herpes, neonatal herpes, and aseptic meningitis. (medscape.com)
Diseases1
- Available at: https://www.aad.org/public/diseases/a-z/herpes-simplex-overview. (epnet.com)
Patients2
- This article presents the results obtained in typing virus strains isolated from 75 middle-class patients of both sexes who in 1985 and 1986 sought dermatological treatment at the Clinical Hospital of the University of Chile for genital lesions which were diagnosed as genital herpes. (paho.org)
- Long-term suppressive therapy should be considered in patients with frequent and severe infections, specifically patients with herpes-associated erythema multiforme or eczema herpeticum. (medscape.com)
Herpetic1
- Oral antiviral medications may be used (off label) as therapy for other uncomplicated HSV conditions (eg, herpetic whitlow), and the same doses as those used for herpes genitalis treatment are commonly recommended. (medscape.com)
Antibodies1
- Prior to a vaginal microbicide trial, 416 women were screened for antibodies to HIV-1 and herpes simplex virus-2 (HSV-2) infections and a questionnaire was used to establish behavioral, social, and demographic characteristics. (nih.gov)
Sexually5
- Genital herpes is a sexually transmitted disease (STD) caused by a herpes simplex virus (HSV). (medlineplus.gov)
- Genital herpes is a sexually transmitted disease (STD) spread by skin-to-skin contact. (adam.com)
- HSV-1 can also cause genital herpes, which is a sexually transmitted disease (STD). (adam.com)
- There are several sexually transmitted infections causing balanoposthitis, such as herpes genitalis (genital herpes), chlamycia and gonhorrea. (imop.gr)
- Genital herpes can affect anyone who is sexually active. (skinsight.com)
Zovirax4
- First attempts a number of tender resets, if those attempts fail, bfgminer is discontinued, affected cube powered along, powered up then bfgminer zovirax cream herpes genitalis restarted. (aljadwal.sa)
- a zovirax pommade et grossesse physician who tells the worker to get ibuprofen over-the-counter and then instructs (but does not document) A different dose (creme zovirax herpes genital) could be needed, or the person will certainly be kept track of thoroughly throughout the treatment. (aljadwal.sa)
- For details on each with the (posologie zovirax herpes genital) schools, understand the links inside resources section below. (aljadwal.sa)
- Having been in the seat, I don't agree with zero tolerance but certainly understand its attraction, especially with the zovirax crema per herpes labiale prezzo number of students one sees during the day at a large school. (aljadwal.sa)
Hepatitis1
- Pregnant women are more severely affected by influenza, hepatitis E, herpes simplex and malaria. (wikipedia.org)
Primary4
- Associates with the HSV-1 type was found in 29 percent of primary and in 10 percent of recurring episodes, whereas 90 percent of the cases of recurring herpes and 71 percent of the primary cases were associated with the HSV-2 type. (paho.org)
- Molecular Evolution of Herpes Simplex Virus 2 Complete Genomes: Comparison between Primary and Recurrent Infections. (emmes.com)
- The primary focus of the examination is on the genitalia. (medscape.com)
- HSV meningitis occurs in about 25%-35% of women and 10%-15% of men at the time of primary episode of genital herpes. (medscape.com)
Clinical2
- www.unboundmedicine.com/5minute/view/5-Minute-Clinical-Consult/1688790/all/Herpes__Genital. (unboundmedicine.com)
- By your clinical description you don't seem to have herpes genitalis. (ndtv.com)
Descriptor1
- Herpes Genitalis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
Antiviral medication1
- Antiviral medication is the standard treatment for both shingles and herpes. (lifeextension.com)
Symptoms4
- Sometimes people do not know they have herpes because they have no symptoms or very mild symptoms. (medlineplus.gov)
- However, genital herpes can also be transmitted when there are no visible symptoms. (adam.com)
- When genital herpes symptoms do appear, they are usually worse during the first outbreak than during recurring attacks. (adam.com)
- Herpes can be spread through genital contact even if there is no evidence that you suffer from symptoms. (acyclovir400mg.com)
Shingles2
- Both herpes and shingles are diagnosed mainly by physical examination. (lifeextension.com)
- Associated topics: herpes - "The patient was successfully treated with topical peppermint oil [for postherpetic neuralgia, a complication of shingles]. (oil-testimonials.com)
Treatment4
- Homeopathy in Hyderabad is worth going in for as an effective treatment of Herpes. (drankireddy.com)
- Most herpes simplex virus (HSV) infections are self-limited and treatment is not always indicated or necessary. (medscape.com)
- Chamomile oil exhibited a high selectivity index and seems to be a promising candidate for topical therapeutic application as virucidal agents for treatment of herpes genitalis. (oil-testimonials.com)
- The treatment of herpes simplex infections: an evidence-based review. (omeka.net)
Oral5
- Biological markers for differentiation of herpes-virus strains of oral and genital origin. (microbiologyresearch.org)
- Herpes simplex virus 1 (HSV-1) is the main cause of oral herpes infections that occur on the mouth and lips. (adam.com)
- Herpes simplex virus 2 (HSV-2) is the most common cause of genital herpes, but it can also cause oral herpes. (adam.com)
- The usual cause of genital herpes, but it can also cause oral herpes. (adam.com)
- Until recently, the general rule was to assume that HSV-1 caused oral herpes and HSV-2 caused genital herpes. (adam.com)
Medicines1
- What are the medicines for herpes genitalis? (drankireddy.com)
Severe1
- This image displays a severe outbreak of herpes in the genital region. (skinsight.com)
Human1
- These studies demonstrate that HerpV is a promising immunotherapy candidate for genital herpes, and provide a foundation for evaluating HerpV in human HSV-2(+) subjects with the intent of eliciting CD4(+) and CD8(+) T cell responses to a broad array of viral antigens. (nih.gov)