OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, Agriculture
HemodilutionHematocritPlasma SubstitutesBlood ViscosityBlood SubstitutesBlood VolumeHydroxyethyl Starch DerivativesBloodlettingOxygenHemoglobinsDextransIsotonic SolutionsMesocricetusPlasma VolumeBlood Volume DeterminationErythrocyte VolumeExchange Transfusion, Whole BloodSpecific GravityCerebrovascular CirculationMicrocirculationBlood Transfusion, AutologousBlood TransfusionHemodynamicsHemorheologyHypovolemiaBlood Loss, SurgicalCardiac OutputCardiopulmonary BypassBlood Gas AnalysisColloidsHypotension, ControlledErythrocyte Transfusion
Hemodilution
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.
Hematocrit
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
Plasma Substitutes
Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.
Blood Viscosity
The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA.
Blood Substitutes
Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.
Blood Volume
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
Hydroxyethyl Starch Derivatives
Starches that have been chemically modified so that a percentage of OH groups are substituted with 2-hydroxyethyl ether groups.
Bloodletting
Puncture of a vein to draw blood for therapeutic purposes. Bloodletting therapy has been used in Talmudic and Indian medicine since the medieval time, and was still practiced widely in the 18th and 19th centuries. Its modern counterpart is PHLEBOTOMY.
Oxygen
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Hemoglobins
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.
Dextrans
A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
Isotonic Solutions
Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)
Mesocricetus
A genus of the family Muridae having three species. The present domesticated strains were developed from individuals brought from Syria. They are widely used in biomedical research.
Plasma Volume
Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.
Blood Volume Determination
Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight.
Erythrocyte Volume
Volume of circulating ERYTHROCYTES . It is usually measured by RADIOISOTOPE DILUTION TECHNIQUE.
Exchange Transfusion, Whole Blood
Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.
Specific Gravity
The ratio of the density of a material to the density of some standard material, such as water or air, at a specified temperature.
Cerebrovascular Circulation
The circulation of blood through the BLOOD VESSELS of the BRAIN.
Microcirculation
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
Blood Transfusion, Autologous
Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)
Blood Transfusion
The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)
Hemodynamics
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Hemorheology
The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.
Hypovolemia
An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).
Blood Loss, Surgical
Loss of blood during a surgical procedure.
Cardiac Output
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Cardiopulmonary Bypass
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
Blood Gas Analysis
Measurement of oxygen and carbon dioxide in the blood.
Colloids
Two-phase systems in which one is uniformly dispersed in another as particles small enough so they cannot be filtered or will not settle out. The dispersing or continuous phase or medium envelops the particles of the discontinuous phase. All three states of matter can form colloids among each other.
Hypotension, Controlled
Procedure in which arterial blood pressure is intentionally reduced in order to control blood loss during surgery. This procedure is performed either pharmacologically or by pre-surgical removal of blood.
Erythrocyte Transfusion
The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.

Effect of acute normovolemic hemodilution on distribution of blood flow and tissue oxygenation in dog skeletal muscle. (1/325)

Acute normovolemic hemodilution (ANH) is efficient in reducing allogenic blood transfusion needs during elective surgery. Tissue oxygenation is maintained by increased cardiac output and oxygen extraction and, presumably, a more homogeneous tissue perfusion. The aim of this study was to investigate blood flow distribution and oxygenation of skeletal muscle. ANH from hematocrit of 36 +/- 3 to 20 +/- 1% was performed in 22 splenectomized, anesthetized beagles (17 analyzed) ventilated with room air. Normovolemia was confirmed by measurement of blood volume. Distribution of perfusion within skeletal muscle was determined by using radioactive microspheres. Tissue oxygen partial pressure was assessed with a polarographic platinum surface electrode. Cardiac index (3.69 +/- 0.79 vs. 4.79 +/- 0.73 l. min-1. m-2) and muscle perfusion (4.07 +/- 0.44 vs. 5.18 +/- 0.36 ml. 100 g-1. min-1) were increased at hematocrit of 20%. Oxygen delivery to skeletal muscle was reduced to 74% of baseline values (0.64 +/- 0.06 vs. 0.48 +/- 0.03 ml O2. 100 g-1. min-1). Nevertheless, tissue PO2 was preserved (27.4 +/- 1.3 vs. 29.9 +/- 1. 4 Torr). Heterogeneity of muscle perfusion (relative dispersion) was reduced after ANH (20.0 +/- 2.2 vs. 13.9 +/- 1.5%). We conclude that a more homogeneous distribution of perfusion is one mechanism for the preservation of tissue oxygenation after moderate ANH, despite reduced oxygen delivery.  (+info)

Hemodilution, cerebral O2 delivery, and cerebral blood flow: a study using hyperbaric oxygenation. (2/325)

Hemodilution reduces blood viscosity and O2 content (CaO2) and increases cerebral blood flow (CBF). Viscosity and CaO2 may contribute to increasing CBF after hemodilution. However, because hematocrit is the major contributor to blood viscosity and CaO2, it has been difficult to assess their relative importance. By varying blood viscosity without changing CaO2, prior investigation in hemodiluted animals has suggested that both factors play roughly equal roles. To further investigate the relationship of hemodilution, blood viscosity, CaO2, and CBF, we took the opposite approach in hemodiluted animals, i.e., we varied CaO2 without changing blood viscosity. Hyperbaric O2 was used to restore CaO2 to normal after hemodilution. Pentobarbital sodium-anesthetized rats underwent isovolumic hemodilution with 6% hetastarch, and forebrain CBF was measured with [3H]nicotine. One group of animals did not undergo hemodilution and served as controls (Con). In the three experimental groups, hematocrit was reduced from 44% to 17-19%. Con and hemodiluted (HDil) groups were ventilated with 40% O2 at 101 kPa (1 atmosphere absolute), which resulted in CaO2 values of 19.7 +/- 1.3 and 8.1 +/- 0.7 (SD) ml O2/dl, respectively. A second group of hemodiluted animals (HBar) was ventilated with 100% O2 at 506 kPa (5 atmospheres absolute) in a hyperbaric chamber, which restored CaO2 to an estimated 18.5 +/- 0.5 ml O2/dl by increasing dissolved O2. A fourth group of hemodiluted animals (HCon) served as hyperbaric controls and were ventilated with 10% O2 at 506 kPa, resulting in CaO2 of 9.1 +/- 0.6 ml O2/dl. CBF was 79 +/- 19 ml. 100 g-1. min-1 in the Con group and significantly increased to 123 +/- 9 ml. 100 g-1. min-1 in the HDil group. When CaO2 was restored to baseline with dissolved O2 in the HBar group, CBF decreased to 104 +/- 20 ml. 100 g-1. min-1. When normoxia was maintained during hyperbaric exposure in the HCon group, CBF was 125 +/- 18 ml. 100 g-1. min-1, a value indistinguishable from that in normobaric HDil animals. Our data demonstrate that the reduction in CaO2 after hemodilution is responsible for 40-60% of the increase in CBF.  (+info)

Extreme, progressive isovolemic hemodilution with 5% human albumin, PentaLyte, or Hextend does not cause hepatic ischemia or histologic injury in rabbits. (3/325)

BACKGROUND: Physicians and their patients are greatly concerned about perioperative blood administration. Although isovolemic hemodilution is utilized to decrease the incidence of transfusion, it is unclear at what degree of hemodilution hepatoenteric ischemia and injury occurs. The authors hypothesized that hepatic ischemia, systemic ischemia, and tissue injury would occur during hemodilution in rabbits, and that the severity of ischemia and injury may be dependent on the fluid administered. METHODS: Rabbits anesthetized with isoflurane were assigned randomly to a sham-operated group (n = 8) or groups that underwent four isovolemic hemodilutions (25% of the blood volume removed at hourly intervals), with blood replaced with one of three solutions: balanced electrolyte solutions containing 6% pentastarch (n = 8), 6% hetastarch (n = 9), or 5% human albumin in normal saline (n = 8). Arterial ketone body ratio and plasma lactate, respectively, served as measures of hepatic and systemic ischemia. Gastric, duodenal, and hepatic histologic injury was assessed post mortem. RESULTS: Hemodilution from a baseline hematocrit of about 33% to about 8% (third hemodilution) with all three colloids did not result in a significant increase in plasma lactate concentration or decrease in arterial ketone body ratio. At a hematocrit of about 5% (fourth hemodilution), the hetastarch group had a significantly (P < 0.05) greater plasma lactate concentration than the sham-operated and 5% human albumin groups. There were no significant differences in arterial ketone body ratio or histologic injury between the groups. CONCLUSIONS: Isovolemic hemodilution (approximately 5% hematocrit) with albumin, pentastarch, or hetastarch solutions does not result in significant hepatic ischemia or injury assessed by histology.  (+info)

Effect of 20% in vitro haemodilution with warmed buffered salt solution and cerebrospinal fluid on coagulation. (4/325)

We have conducted an in vitro coagulation study consisting of two separate groups of 20 subjects using the thrombelastograph. In the first group, haemodilution was performed with a physiological balanced salt solution similar to plasma, with the exception of calcium, and buffered to a normal pH (Plasmalyte B) at 37 degrees C on blood obtained from consenting volunteers. In the second group, a protein-poor body fluid (cerebrospinal fluid (CSF)) obtained from parturient patients undergoing spinal anaesthesia for Caesarean section was used as the diluent. There were statistically significant differences between the warmed Plasmalyte B treated samples and their untreated controls for all variables measured by the thrombelastograph, except for maximum amplitude, and between the CSF treated samples and their untreated controls for all variables. We conclude that electrolyte and acid-base composition of the diluent fluid had no effect on the observation that crystalloid haemodilution produces hypercoagulability. The marked increase in coagulability produced by addition of CSF cannot be explained on a simple haemodilution basis and confirms previous suggestions of the presence of a procoagulant factor in CSF.  (+info)

Repetitive hemodilution in chronic obstructive pulmonary disease and pulmonary hypertension: effects on pulmonary hemodynamics, gas exchange, and exercise capacity. (5/325)

BACKGROUND: In cor pulmonale associated with severe chronic obstructive pulmonary disease (COPD), disturbances of pulmonary microcirculation may contribute significantly to hypoxemia, pulmonary hypertension, and exercise intolerance. OBJECTIVE: It was tested whether reduction of blood viscosity induced by repetitive hemodilution might improve pulmonary hemodynamics and oxygen uptake. METHODS: Seven patients with stable COPD (forced expiratory volume in 1 s 33 +/- 3 % of predicted, means +/- SE) and pulmonary hypertension were phlebotomized 5-6 times over a period of 3 months with substitution of 6% hydroxyethyl starch (molecular weight 40, 000). This resulted in a stepwise reduction of the hematocrit from 53.3 +/- 2.6 to 45.8 +/- 3.1% and a reduction of whole blood viscosity from 9.8 +/- 0.6 to 8.8 +/- 0.7 mPa x s at a shear rate of 2.0 s-1. Before and after the treatment period, patients underwent cardiopulmonary exercise testing and right heart catheterization. RESULTS: Mean pulmonary artery pressure (PAm) decreased from 30 +/- 3 to 22 +/- 2 mm Hg and arterial oxygen partial pressure (PaO2) increased from 63.2 +/- 2.2 to 71.8 +/- 3.7 mm Hg at rest. During peak exercise, PAm decreased from 59 +/- 7 to 53 +/- 7 mm Hg and PaO2 increased from 54.0 +/- 5.7 to 63.2 +/- 2.4 mm Hg after hemodilution. Peak oxygen consumption rose from 573 +/- 84 to 750 +/- 59 ml x min-1, corresponding to an increase in cardiac index from 4.25 +/- 0.5 to 5.88 +/- 0.76 liters x min-1 x m-2. Pulmonary vascular resistance fell from 345 +/- 53 to 194 +/- 32 dyn x s x cm-5. The patients' peak exercise capacity increased from 9.2 +/- 2. 0 before to 13.5 +/- 3.2 kJ at the end of the study (p < 0.05 for all differences, paired t test). CONCLUSION: The findings suggest that a prolonged improvement of pulmonary microcirculation by reducing blood viscosity may improve pulmonary gas exchange, central hemodynamics, and exercise tolerance in patients with severe COPD and pulmonary hypertension.  (+info)

Acute normovolaemic haemodilution vs controlled hypotension for reducing the use of allogeneic blood in patients undergoing radical prostatectomy. (6/325)

Blood loss in patients undergoing radical prostatectomy may be substantial. In a randomized, prospective study, we assessed two methods of reducing the need for allogeneic blood transfusion with regard to efficacy and costs. Sixty patients undergoing retropubic radical prostatectomy were allocated randomly to one of three groups. In group 1 (n = 20), acute normovolaemic haemodilution (ANH) was initiated after induction of anaesthesia; autologous blood 15 ml kg-1 was withdrawn and replaced by colloid solutions (gelatin) to maintain haemodynamic stability. In group 2 (n = 20), controlled hypotension was established using sodium nitroprusside (target mean arterial pressure (MAP) approximately 50 mm Hg). Group 3 (n = 20), without manipulations, served as a control group. Troponin T (TnT), a sensitive marker for myocardial ischaemia, and various coagulation variables were measured in the perioperative period. Packed red blood cells (PRBC) were given when haemoglobin concentration was less than 7 g dl-1. Cost calculations did not include hospital overhead costs or staff costs. In the ANH group, mean 1278 (SD 150) ml of autologous blood were withdrawn. Significantly more volume was infused in the ANH patients (gelatin 2450 (550) ml) than in the two other groups. Coagulation data (platelet count, activated partial thromboplastin time (aPTT), fibrinogen, antithrombin III (AT III), D-dimers) did not differ significantly between the three groups. The hypotension group had significantly lower blood loss (1260 (570) ml), whereas the ANH (1820 (680) ml) and control group (1920 (590) ml) did not differ significantly. Patients in the hypotension group needed significantly less PRBC (total 14 units; 75% of patients did not need PRBC) than the ANH (total 21 units; 55% of patients did not need PRBC) or control patients (total 28 units; 40% of patients did not need PRBC). Total costs were lowest in the hypotension group (41% less than in the control patients) (P < 0.05). We conclude that the use of hypotension during radical prostatectomy resulted in approximately 40% reduction in total transfusion costs. ANH was less effective and more costly than controlled hypotension.  (+info)

Pulse oximetry plethysmographic waveform during changes in blood volume. (7/325)

Systolic pressure variation (SPV) and its dDown component have been shown to be sensitive factors in estimating intravascular volume in patients undergoing mechanical ventilation. In this study, ventilation-induced changes in pulse oximeter plethysmographic waveform were evaluated after removal and after reinfusion of 10% estimated blood volume. The plethysmographic waveform variation (SPVplet) was measured as the difference between maximal and minimal peaks of waveform during the ventilatory cycle, and expressed as a percentage of the signal amplitude during apnoea. dUp(plet) and dDown(plet) were measured as the distance between the apnoeic plateau and the maximal or minimal plethysmographic systolic waveform, respectively. Intravascular volume was changed by removal of 10% of estimated blood volume and followed by equal volume replacement with Haemaccel. A 10% decrease in blood volume increased SPVplet from mean 17.0 (SD 11.8)% to 31.6 (28.0)% (P = 0.005) and dDown(plet) from 8.7 (5.1)% to 20.5 (12.9)% (P = 0.0005) compared with baseline. Changes in plethysmographic waveform correlated with changes in arterial SPV and dDown (r = 0.85; P = 0.0009). In the absence of invasive arterial pressure monitoring, ventilation-induced waveform variability of the plethysmographic signal measured from pulse oximetry is a useful tool in the detection of mild hypovolaemia.  (+info)

Cerebral response to haemodilution during cardiopulmonary bypass in dogs: the role of nitric oxide synthase. (8/325)

During cardiopulmonary bypass, haemodilution is standard practice and is accompanied by increases in cerebral blood flow (CBF). We investigated if changes in cerebral vascular resistance (CVR) during cardiopulmonary bypass-haemodilution are dependent on nitric oxide synthase. The cerebral response to haemodilution in nine dogs treated with the nitric oxide synthase inhibitor, N omega-nitro-L-arginine methyl ester (L-NAME), was compared with a control group (n = 8). Both groups underwent serial isovolaemic haemodilution (target packed cell volumes 0.39, 0.26, 0.19 and 0.14) using 6% dextran 70. CBF, CVR and cerebral metabolic rate for oxygen (CMRO2) were measured. While initial CVR was different in the two groups, haemodilution-dependent reductions in CVR were equivalent and the curves describing the packed cell volume-CVR relationship were parallel in control and nitric oxide synthase inhibition groups. Our data indicate that nitric oxide synthase does not play a primary role in the cerebral response to haemodilution.  (+info)

Responsiveness of stroke volume variation and central venous pressure during acute normovolemic and hypervolemic hemodilution<...
TY - JOUR. T1 - Responsiveness of stroke volume variation and central venous pressure during acute normovolemic and hypervolemic hemodilution. AU - Ji, Fu Hai. AU - Li, Wen Jing. AU - Li, Jiang. AU - Peng, Ke. AU - Yang, Jian Ping. AU - Liu, Hong. PY - 2013/5/20. Y1 - 2013/5/20. N2 - Background Stroke volume variation (SVV) is a robust indicator of fluid responsiveness during volume change. We compared the sensibility of SVV by Vigileo/Flotrac to central venous pressure (CVP) when volume changes in patients undergoing intraoperative acute normovolemic hemodilution (ANH) and acute hypervolemic hemodilution (AHH). Methods Forty patients were randomly divided into an ANH group (n=20) and an AHH group (n=20). All patients received general anesthesia and were mechanically ventilated. Data were collected from 7 different time-points in the ANH group: baseline, after withdrawal of 5%, 10%, and 15% of the estimated blood volume (EBV) and after replacement with an equal volume of 6% hydroxyethyl starch ...
https://ucdavis.pure.elsevier.com/en/publications/responsiveness-of-stroke-volume-variation-and-central-venous-pres
GastroHep News StoryGastroHep News Story
In the acute normovolemic hemodilution group, intraoperative blood collection was performed to a target hemoglobin of 8.0 g/dL. Low central venous pressure anesthetic technique was used intraoperatively for both groups. A standardized transfusion protocol was applied to all patients intraoperatively and throughout the hospital stay.. The researchers randomized 63 patients to acute normovolemic hemodilution, and 67 to standard anesthetic management from 2004 to 2007.. Demographics, diagnoses, liver function, extent of resection, intraoperative blood loss, operative time, incidence and grade of complications, and length of hospital stay were similar between the 2 groups. The team found that acute normovolemic hemodilution reduced the overall allogeneic red cell transfusion rate by 50% compared with standard anesthetic management. Acute normovolemic hemodilution patients were less often transfused intraoperatively compared with the standard anesthetic management group.. The research team noted that ...
http://www.gastrohep.com/news/news.asp?id=105997
Revisiting acute normovolemic hemodilution and blood transfusion during pediatric cardiac surgery: a prospective observational...Revisiting acute normovolemic hemodilution and blood transfusion during pediatric cardiac surgery: a prospective observational...
Children undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at high risk of being exposed to relatively large volumes of allogeneic blood products. If blood transfusion can be life-saving in some circumstances (e.g. major haemodilution or massive haemorrhage), the administration of large volumes of allogeneic blood products has been shown to significantly increase the risk of postoperative complications. Over the last decades, different strategies have been developed to reduce the need for blood product transfusions.. Acute normovolemic hemodilution (ANH) has been used for a long time in adults undergoing high bleeding risk procedures, including cardiac surgery. While some studies reported a decrease in the incidence of transfusion and in the volume of red blood cells transfused, only limited evidence exists in infants and children undergoing cardiac surgery. Major differences exist between children and adults undergoing cardiac surgery, limiting the use of ANH to a small number of ...
https://nataonline.com/2017/04/02/revisiting-acute-normovolemic-hemodilution-and-blood-transfusion-during-pediatric-cardiac-surgery-a-prospective-observational-study/
Acute Normovolemic Hemodilution in Patients Undergoing Cytoreductive Surgery for Advanced Ovarian Cancer - Full Text View -...Acute Normovolemic Hemodilution in Patients Undergoing Cytoreductive Surgery for Advanced Ovarian Cancer - Full Text View -...
The purpose of this study is to help us learn how to lower the risk of a blood transfusion during surgery to remove ovarian cancer. Acute normovolemic hemodilution (ANH) is a technique performed in the operating room before the procedure begins that may reduce the risk of needing a transfusion during ovarian cancer surgery. During surgery, the patients own blood is given back to them when needed, usually due to bleeding. If you dont need blood during surgery, your own blood will be given back at the end of the case.. The idea behind ANH is that that by removing the blood and replacing it with other fluids, the remaining blood becomes diluted. This diluted blood is then lost during surgery, usually due to bleeding. The original non-diluted blood is then transfused back as needed. This may mean a lower chance of needing an additional blood transfusion.. ANH has been studied at this hospital for other types of cancer. These studies suggest that ANH may help conserve blood. Although most studies ...
https://clinicaltrials.gov/ct2/show/NCT01442051?term=ovarian+cancer&recr=Open&rank=19
Isovolemic hemodilution in experimental focal cerebral ischemia. Part 1: Effects on hemodynamics, hemorheology, and...
TY - JOUR. T1 - Isovolemic hemodilution in experimental focal cerebral ischemia. Part 1. T2 - Effects on hemodynamics, hemorheology, and intracranial pressure. AU - Tu, Y. K.. AU - Heros, R. C.. AU - Candia, G.. AU - Hyodo, A.. AU - Lagree, K.. AU - Callahan, R.. AU - Zervas, N. T.. AU - Karacostas, D.. PY - 1988/1/1. Y1 - 1988/1/1. N2 - A total of 76 splenectomized dogs were entered in a study of the value and effects of isovolemic hemodilution. Of these, seven were not included in the analysis because of technical errors. Of the remaining 69 dogs, 35 were treated with hemodilution; 28 were subjected to a 6-hour period of temporary occlusion of the distal internal carotid artery and the proximal middle cerebral artery, and seven underwent a sham operation only, with arterial manipulation but no occlusion. The other 34 dogs were not subjected to hemodilution; 26 of these underwent temporary arterial occlusion and eight had a sham operation only. In each group the animals were about equally ...
https://tmu.pure.elsevier.com/en/publications/isovolemic-hemodilution-in-experimental-focal-cerebral-ischemia-p
Simultaneous investigations of maternal cardiac output and fetal blood flow during hypervolemic hemodilution in preeclampsia -...Simultaneous investigations of maternal cardiac output and fetal blood flow during hypervolemic hemodilution in preeclampsia -...
Simultaneous investigations of maternal cardiac output and fetal blood flow during hypervolemic hemodilution in preeclampsia - preliminary ...
https://edoc.hu-berlin.de/handle/18452/13651
Cardiovascular response to hyperoxemia, hemodilution and burns : a clinical and experimental studyCardiovascular response to hyperoxemia, hemodilution and burns : a clinical and experimental study
The last decades less invasive monitoring and analytical tools have been developed for the evaluation of myocardial mechanics in clinical praxis. In critical care, these are longed-for complements to pulmonary artery catheter monitoring, additionally offering previously inaccessible information. This work is aimed, during fluid-replacement and oxygen therapy, to determine the physiological interface of ventricular and vascular mechanical properties, which result in the transfer of blood from the heart to appropriate circulatory beds. In prospective clinical studies we investigated previously cardiovascular healthy adults during hyperoxemia, and during preoperative acute normovolemic hemodilution or early fluid resuscitation of severe burn victims. Echocardiography was used in all studies, transthoracic for healthy volunteers and transesophageal for patients. For vascular parameters and for control purposes pulmonary artery Swan-Ganz catheter, calibrated external pulse recordings, whole body ...
http://liu.diva-portal.org/smash/record.jsf?pid=diva2:17348
Clinical Hemorheology and Microcirculation - Volume 67, issue 2 - Journals - IOS PressClinical Hemorheology and Microcirculation - Volume 67, issue 2 - Journals - IOS Press
Authors: Kim, Doosang , Cho, Daniel J. , Cho, Young I. Article Type: Research Article Abstract: AIMS: Critical limb ischemia (CLI) patients are characterized by intractable pain in spite of medication, non-healing ulcers, and gangrene. The objective of this study was to investigate whether or not isovolemic hemodilution treatment can reduce the rate of major amputations in CLI. METHODS: 28 patients were studied who had tissue loss on Rutherford Grade III, Category 5 or 6. The subjects were divided into two arms: standard-of-care, conventional therapy (CT) (n = 15) as a control group and hemodilution therapy (HT) (n = 13) as a study group. For the HT group, weekly isovolemic hemodilution was performed over 4 consecutive …weeks, removing 250 ml of whole blood with the infusion of hydroxyl-ethyl starch solution. Blood viscosity, hematocrit, hemoglobin, ankle-brachial index, VA pain scale, time-to-amputation from admission, and survival time were measured. RESULTS: The mean Hct gradually decreased ...
https://content.iospress.com/journals/clinical-hemorheology-and-microcirculation/67/2
Solute mass balance during isovolaemic high volume haemofiltration<...
TY - JOUR. T1 - Solute mass balance during isovolaemic high volume haemofiltration. AU - Uchino, Shigehiko. AU - Cole, Louise. AU - Morimatsu, Hiroshi. AU - Goldsmith, Donna. AU - Ronco, Claudio. AU - Bellomo, Rinaldo. PY - 2003/9/1. Y1 - 2003/9/1. N2 - Objective: To evaluate the effect of changing the amount of pre-dilution replacement fluid on the sieving coefficient (SC) and mass transfer of small solutes during isovolaemic high-volume haemofiltration (HVHF). Design and setting: Prospective interventional study in the intensive care unit of a tertiary university hospital. Patients: Eight patients with septic shock. Interventions: Isovolaemic HVHF (6 1/h of replacement fluid) was performed. The proportion of replacement fluid delivered in pre-filter was altered to progressively decrease it from 6 to 0 l/h. Samples were simultaneously taken from the pre-filter, post-filter and ultrafiltrate (UF) sampling ports. Measurements and results: Sodium, potassium, chloride, total calcium, total ...
https://okayama.pure.elsevier.com/en/publications/solute-mass-balance-during-isovolaemic-high-volume-haemofiltratio
Tolerance to acute isovolemic hemodilution. Effect of anesthetic depth. - PubMed - NCBITolerance to acute isovolemic hemodilution. Effect of anesthetic depth. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/12826848?dopt=Abstract
Case report: intraoperative management of extreme hemodilution in a patient with a severed axillary arteryCase report: intraoperative management of extreme hemodilution in a patient with a severed axillary artery
We present a case of extreme hemodilution in which appropriately crossmatched blood was not available. A 53-year-old man was admitted to our hospital because of hemorrhagic shock due to multiple stab wounds. His blood type was B, Rh negative, and his intravascular fluid volume was maintained with ba …
https://pubmed.ncbi.nlm.nih.gov/20581160/
Improvement in wound healing in ischaemic limbs by perioperative normovolaemic haemodilution - an animal study - IOS PressImprovement in wound healing in ischaemic limbs by perioperative normovolaemic haemodilution - an animal study - IOS Press
To test the hypothesis that lowering the haemoglobin concentration pre-operatively improves wound healing 52 Wistar rats were randomly allocated into two groups: group A were haemodiluted pre-operatively by ten per cent of their blood volume; group
https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch6-6-07
Hypervolemic hemodilution after stroke. | StrokeHypervolemic hemodilution after stroke. | Stroke
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http://stroke.ahajournals.org/content/17/4/777.1
Asymptomatic carotid disorder and hemodilution: a perioperative study in major orthopaedic surgery.<...
TY - JOUR. T1 - Asymptomatic carotid disorder and hemodilution. T2 - a perioperative study in major orthopaedic surgery.. AU - Bombardini, T.. AU - Borghi, B.. AU - Mattioli, R.. AU - Gargioni, G.. PY - 1995/1. Y1 - 1995/1. N2 - The aim of this study was to assess the pattern of adaptation to severe Haemodilution in pts with normal or stenotic carotid vessels. We enrolled 180 consecutive pts undergoing total hip replacement: 138 pts had echo-Doppler documented normal carotid arteries, 10 pts had kinking and 32 pts had monolateral or bilateral stenosis of internal carotid arteries (lesions, class of stenosis 1-49%). Haemoglobin values on the 4th day after surgery was 8.7 +/- 1.2 g/dl with no statistically significant differences in pts (patients) with carotid disorders versus normal pts. No pt showed clinical signs of cerebral ischemia or brain damage in the postoperative period. These results are consistent with experimental and clinical data showing that normovolaemic anaemia is well tolerated ...
https://moh-it.pure.elsevier.com/en/publications/asymptomatic-carotid-disorder-and-hemodilution-a-perioperative-st
Adelaide Research & Scholarship: Drowning, haemodilution, haemolysis and staining of the intima of the aortic root -...Adelaide Research & Scholarship: Drowning, haemodilution, haemolysis and staining of the intima of the aortic root -...
In order to demonstrate that hyponatraemia due to haemodilution occurs within the left ventricle following freshwater drowning, and to determine whether lysed blood resulting from left ventricular haemodilution may cause staining of the aortic intima, the following studies were undertaken. Measurements of left ventricular sodium levels were performed in 74 consecutive coronial cases where death was attributed to drowning, consisting of 44 and 30 deceased who were believed to be victims of freshwater and saltwater drowning, respectively. Left ventricular sodium levels differed significantly between the two groups (p , 0.001), with a range of 93-147 mmol/L in freshwater drowning (mean = 117 ± 14.2 mmol/L) and 123-183 in saltwater drowning (mean = 153 ± 14.4 mmol/L). In addition, the mean sodium level of 117 mmol/L in freshwater drowning was significantly lower than the standard range of 137-145 mmol/L. In a second study, portions of aorta and pulmonary trunk from a euthanised pig were soaked in ...
https://digital.library.adelaide.edu.au/dspace/handle/2440/23111
Indian Patents. 280060:A DEVICE OF HEMODILUTION TRANSFUSION FOR COLLECTION AND REINFUSION OF HUMAN BLOOD,PLASTIC STRIPPERS AND...
The present invention relates to a system for the collection and re-infusion of blood in to a human body just before surgery. More specifically, it is a system and method for the collection and re-infusion blood to human body. It is used for collecting the blood just before the surgery within a short span of time and anti-coagulating patients blood for re-infusion in to the same patient. In this invention, two single tube segments are connected to two PVC blood bags as shown in the figure (1). Then these tubes are connected to Y connector through the roller cum stripper and 5 clamps and the same is then connected to the gauze needle covered with needle safety shield. The transfusion bag is provided with a Rotary shaker for the mixing of the solution with blood so that the time of the clinicians can be saved. Alternatively, a printed scale is provided on b side of the bag, and one S hook is provided at the lowest part of the bag which helps to collect blood in the OT without the help of any ...
https://www.allindianpatents.com/patents/280060-a-device-of-hemodilution-transfusion-for-collection-and-reinfusion-of-human-blood-plastic-strippers-and-the-process-thereof
The Single Best Strategy To Use For gastroscopy preparationThe Single Best Strategy To Use For gastroscopy preparation
Hemodilution was avoided with the drainage of irrigation fluid via a remaining ventricular cannula. Results: Direct endoscopic visualization of your mitral valve within an in vivo beating coronary heart was acquired Evidently, avoiding systemic hemodilution. In the final experiment, edge-to-edge restore applying an endoscopic clip was productively executed. Use of an effective intracardiac irrigation strategy was essential for prosperous image acquisition and achievement of fix procedures. Conclusions: This acute animal review showed the specialized feasibility of beating-coronary heart mitral valve medical procedures below direct endoscopic imaging. Despite the fact that this analyze was carried out underneath open up-upper body problems, our effective experiment is often a starting point towards closed-upper body intracardiac surgery with direct endoscopic visualization ...
http://trentonugrc358.tinyblogging.com/The-Single-Best-Strategy-To-Use-For-gastroscopy-preparation-8723197
Anh dung Meaning, Anh dung name meaningAnh dung Meaning, Anh dung name meaning
Anh dung name meaning, Vietnamese baby Boy name Anh dung meaning,etymology, history, presonality details. Anh dung Rhyming, similar names and popularity.
https://www.babynology.com/name/anh--dung-m.html
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CT - So, if you had to cast an ANH remake . . . | Jedi Council ForumsCT - So, if you had to cast an ANH remake . . . | Jedi Council Forums
Yes, the suggestion itself is blasphemy, I know. Im not at all suggesting it be done. This is just a hypothetical!! So, in this thought-experiment,...
http://boards.theforce.net/threads/so-if-you-had-to-cast-an-anh-remake.50011698/
Hypervolemia increases release of atrial natriuretic peptide and shedding of the endothelial glycocalyxHypervolemia increases release of atrial natriuretic peptide and shedding of the endothelial glycocalyx
Acute normovolemic hemodilution (ANH) and volume loading (VL) are standard blood-sparing procedures. However, VL is associated with hypervolemia, which may cause tissue edema, cardiopulmonary complications and a prolonged hospital stay. The body reacts to hypervolemia with release of atrial natriuretic peptide (ANP) from the heart. ANP has been shown to deteriorate the endothelial glycocalyx, a vital part of the vascular permeability barrier. The aim of the present study was to evaluate and compare ANP release and damage to the glycocalyx during ANH and VL. ...
https://epub.ub.uni-muenchen.de/24898/index.html
Iatrogenic hemodilution: a possible cause for avoidable blood transfusions? | Critical Care | Full TextIatrogenic hemodilution: a possible cause for avoidable blood transfusions? | Critical Care | Full Text
In one of the largest randomized controlled trials (RCTs) on GDT, the incidence of blood transfusions was double (22 vs 11%) in the GDT group patients, who received nearly twice the amount of colloids compared to the control group, even though the same transfusion threshold (Hb , 8 g/dl) was used for both groups [11]. The most feasible explanation for this clinically relevant and statistically significant difference (p = 0.04 based on a chi square test), which was not calculated nor discussed in the article [11], is that more patients in the GDT group reached Hb levels below the transfusion threshold due to hemodilution, prompting physicians to order blood transfusions. Other RCTs have also reported that patients in the GDT group, who received significantly more colloid boluses, received significantly more blood transfusions [12, 13] and had significantly higher blood loss [13] compared to the standard therapy group. In another study, the administration of more colloids led to lower Hb and DO2 ...
https://ccforum.biomedcentral.com/articles/10.1186/s13054-017-1872-1
Hemodilution and Outcome in Cardiac Surgery - Full Text View - ClinicalTrials.govHemodilution and Outcome in Cardiac Surgery - Full Text View - ClinicalTrials.gov
An hematocrit of 21-25% is supposed to perform the best organ protection during cardiopulmonary bypass for cardiac surgery.. The investigators want to establish the best timing for a transfusion (in patients with a predicted low hematocrit during cardiopulmonary bypass) and the efficacy of preprocedural hemodilution (in patients with a predicted high hematocrit during cardiopulmonary bypass) in patients undergoing cardiac surgery. ...
https://clinicaltrials.gov/ct2/show/NCT00364494
Hemodilution | Harvard Catalyst Profiles | Harvard CatalystHemodilution | Harvard Catalyst Profiles | Harvard Catalyst
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Hemodilution
JoVE Author Search: Carboni G
Acute Kidney Injury, Adult, Association, Bleeding, Blood, Cardiac Output, Cardiac Surgery, Confidence Interval, Hematocrit, Hemodilution, Hospital, Injury, Kidney, Low Cardiac Output, Mechanical Ventilation, Methods, Morbidity, Mortality, Odds Ratio, Patient
http://labindex.jove.com/author/Carboni-G
Upplevelser av rollen som anhörigvårdare till person som drabbats av strokeUpplevelser av rollen som anhörigvårdare till person som drabbats av stroke
Bakgrund: När en person drabbats av stroke är det i många fall även närstående som påverkas och måste anpassa sig till den nya situationen. Syfte: Syftet var att beskriva negativa respektive positiva upplevelser av att vara anhörigvårdare till en person som drabbats av stroke. Metod: Litteraturöversikt med granskning av 15 kvalitativa studier publicerade mellan åren 2006-2012. Resultat: Utifrån anhörigvårdarnas upplevelser av vårdarbetet framkom tio teman. Huvudresultatet var att de upplevde vårdarbetet som betungande, utmattande, bekymrande med brist på egentid och avlastning. De upplevde också brist på stöd från familj, vänner, samhälle och sjukvård. Anhörigvårdarna upplevde sig utlämnade och oförberedda i sin nya roll som vårdare och ansåg sig inte ha fått tillräcklig undervisning i vad rollen skulle innebära och vad de kunde förvänta sig. De positiva upplevelserna var att relationerna stärktes inom familjerna och anhörigvårdarna lärde sig att uppskatta ...
http://www.diva-portal.org/smash/record.jsf?pid=diva2:599055
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Abbreviates nghĩa là gì ? | Từ Điển Anh Việt EzyDictAbbreviates nghĩa là gì ? | Từ Điển Anh Việt EzyDict
Abbreviates nghĩa là gì ? abbreviate /əbri:vieit/ * ngoại động từ - tóm tắt, viết tắt; rút ngắn lại (cuộc đi thăm...) - (toán học) ước lược, rút...
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Hemato-clad* Mylar*-wrapped Hematocrit Tubes - Id: 1.1 To 1.2mm;3080677pk
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MAPK Signalweg | www.antikoerper-online.deMAPK Signalweg | www.antikoerper-online.de
Phosphorylierung ist das reversible Anhängen einer Phosphatgruppe an einen spezifischen Aminosäurerest eines Moleküls. Auf funktionaler Ebene dient die Phos...
https://www.antikoerper-online.de/mapk-signalweg-pathway-3/
Hematocrit - Diseases and Condition - 16803Hematocrit - Diseases and Condition - 16803
Search information on Hematocrit (16803) and 1000s of other diseases, symptoms, drugs, doctors, specialists, and clinics in our trustworthy medical i
http://www.diabeteshealthmatters.com/disease/7-16803/hematocrit
Anesthetic management for ascending aorta replacement in a patient who refused autologous transfusion for religious reasons -...Anesthetic management for ascending aorta replacement in a patient who refused autologous transfusion for religious reasons -...
We report on the anesthetic management of a 69-year-old female Jehovahs Witness undergoing cardiopulmonary bypass to replace the ascending aorta; the patient refused transfusion of stored autologous or allogeneic blood products for religious reasons. The strategy involved preoperative hematopoiesis with recombinant human erythropoietin and iron, intraoperative acute normovolemic hemodilution, the use of a cell-saver system, administration of high-dose tranexamic acid, controlled hypotension, avoidance of low body temperature, simplification of the surgery, and lower blood dilution during cardiopulmonary bypass.
https://www.semanticscholar.org/paper/Anesthetic-management-for-ascending-aorta-replacem-Obara-Nakagawa/a39affdd0226c4f978f573e309d7897c0ae61b05
Adult cardiopulmonary bypass in Australian and New Zealand public hospitals: A survey of practiceAdult cardiopulmonary bypass in Australian and New Zealand public hospitals: A survey of practice
View more ,A telephone survey of cardiac anaesthetists and perfusionists at the 29 public hospitals providing adult cardiac surgical services in Australia and New Zealand was carried out between December 2019 and January 2020. The aim was to investigate current practice with regard to selected contentious elements of anaesthetic and perfusion management during cardiopulmonary bypass; primarily relating to bypass circuit priming, blood conservation methods and point-of-care coagulation testing. There was a 100% response rate. The average number of adult public cardiopulmonary bypass cases per hospital was 508 (160-1400). For cardiopulmonary bypass cases, ten hospitals (34%) routinely used a cell saver and the remainder used a cell saver selectively. Residual blood remaining in the cardiopulmonary bypass circuit was processed using a cell saver routinely in four hospitals (14%) and selectively in 23 (79%). Acute normovolaemic haemodilution was rarely used. Retrograde autologous priming was used ...
https://research-repository.griffith.edu.au/handle/10072/400069
CME Effect of Intravenous Ferric Carboxymaltose on Hemoglobin Response Among Patients With Acute Isovolemic Anemia Following...
Please provide below the URL and description of an activity you would like to add to OpenCME. You are welcome to add activities as often as you like. To prevent spam or other abuse, activities are reviewed by our editorial team before appearing on OpenCME. ...
http://opencme.org/course/effect-of-intravenous-ferric-carboxymaltose-hemoglobin-response-among-patients-acute-isovolem
Iron metabolism defined using stable isotopes in obesity</em>...Iron metabolism defined using stable isotopes in obesity</em>...
TY - CONF. T1 - Iron metabolism defined using stable isotopes in obesity. AU - Isabelle Herter-Aeberli. AU - Michael B. Zimmermann. AU - Cepeda López, Ana Carla. PY - 2018/12/8. Y1 - 2018/12/8. N2 - Introduction Iron deficiency is common in overweight (OW) and obese (OB) individuals and was shown to be at least partially mediated by adiposity-related inflammation. The proinflammatory cytokine interleukin 6 (IL6) induces hepcidin expression which may lead to decreased intestinal iron absorption. On the other hand, greater blood volume in OW/OB individuals may increase hemoglobin mass and iron requirements and confound iron biomarkers by hemodilution. Using stable iron isotopes, we have systematically studied iron metabolism in obesity. We have answered the following questions: 1) to what extent is hemodilution responsible for low iron status in OW/OB individuals; 2) what is the difference in iron absorption in OW/OB compared to normal weight (NW) participants and to what extent can ascorbic acid ...
https://pure.udem.edu.mx/en/publications/iron-metabolism-defined-using-stable-isotopes-in-obesity
OPUS 4 | SearchOPUS 4 | Search
Background: Clonidine effectively decreases perioperative mortality by reducing sympathetic tone. However, application of clonidine might also restrict anaemia tolerance due to impairment of compensatory mechanisms. Therefore, the influence of clonidine induced, short-term sympathicolysis on anaemia tolerance was assessed in anaesthetized pigs. We measured the effect of clonidine on anaemia tolerance and of the potential for macrohemodynamic alterations to constrain the acute anaemia compensatory mechanisms. Methods: After governmental approval, 14 anaesthetized pigs of either gender (Deutsche Landrasse, weight (mean ± SD) 24.1 ± 2.4 kg) were randomly assigned to intravenous saline or clonidine treatment (bolus: 20 μg · kg−1, continuous infusion: 15 μg · kg−1 · h−1). Thereafter, the animals were hemodiluted by exchange of whole blood for 6 % hydroxyethyl starch (MW 130.000/0.4) until the individual critical haemoglobin concentration (Hbcrit) was reached. Primary outcome parameters ...
http://publikationen.ub.uni-frankfurt.de/solrsearch/index/search/searchtype/authorsearch/author/Patrick+Lauscher/start/0/rows/10/author_facetfq/Jens+Meier
hematocrit | The Trauma Prohematocrit | The Trauma Pro
Does Initial Hematocrit Predict Shock?. Everything you know is WRONG!. The classic textbook teaching is that trauma patients bleed whole blood. And that if you measure the hematocrit (or hemoglobin) on arrival, it will approximate their baseline value because not enough time has passed for equilibration and hemodilution. As Ive said before, youve got to be willing to question dogma!. The trauma group at Ryder in Miami took a good look at this assumption. They drew initial labs on all patients requiring emergency surgery within 4 hours of presentation to the trauma center. They also estimated blood loss in the resuscitation room and OR and compared it to the initial hematocrit. They also compared the hematocrit to the amount of crystalloid and blood transfused in those areas.. Patients with lower initial hematocrits had significantly higher blood loss and fluid and blood replacement during the initial treatment period. Some of this effect may be due to the fact that blood loss was ...
https://thetraumapro.com/tag/hematocrit/
Ngân hàng đề thi học kì 1 môn tiếng anh 7 8 - Tài liệu text
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ARTICLES | Journal of Applied Physiology
In this study, we investigated the mechanisms underlying the changes in intestinal microcirculatory oxygenation induced by acute normovolemic HD. Our results show that severe HD is associated with redistribution of O2 delivery away from the intestines and also shunting of the residual O2 within the intestines itself. The correlation between mucosal μHbO2 and μPo2 during reduction of intestinal microvascular oxygenation indicates that impaired erythrocyte O2 off-loading is not the key mechanism responsible for the decreased microcirculatory mucosal oxygenation. Thus O2 shunting bypassing the microcirculation to the venous compartment appears to be the main factor. Herein, rheological alterations may contribute, and a potential candidate is the observed erythrocyte rigidification during ANH.. In HD pigs, mucosal μHbO2 was well preserved during mild ANH but finally progressively declined. This finding of a two-phase response of intestinal microvascular oxygenation (maintained oxygenation during ...
http://jap.physiology.org/content/98/3/1070.featured-podcasts
Basic Metabolic Panel with Ionized Calcium - United Clinical Laboratories Test Catalog
Hemodilution of the plasma by more than 20% associated with priming cardiopulmonary bypass pumps, plasma volume expansion or other fluid administration therapies using certain solutions may cause clinically significant error on ionized calcium results. These errors are associated with solutions that do not match the ionic characteristics of plasma. To avoid these errors when hemodiluting by more than 20%, use physiologically balanced multi-electrolyte solutions containing low-mobility anions (e.g. Gluconate) such as Normosol-R (Abbott Laboratories), Plasma-Lyte-A (Baxter Healthcare oCrporation), and Isolyte-S (B Braun Medical) rather than solutions such as normal saline or ringers lactate.. ...
http://ucl.testcatalog.org/show/180
Changes in Important Biochemical Parameters Due to Extreme Haemodilution with Cross-linked Stromafree Haemoglobin Solution |...Changes in Important Biochemical Parameters Due to Extreme Haemodilution with Cross-linked Stromafree Haemoglobin Solution |...
Transport of biological available oxygen in vertebrates is performed by two different principles: physical solution in plasma and chemical binding to the haemoglobin molecule. According to these...
https://link.springer.com/chapter/10.1007/978-3-642-71328-6_25
Pregnancy and Fertility - Multiple Myeloma - ALPF Medical ResearchPregnancy and Fertility - Multiple Myeloma - ALPF Medical Research
The natural physiological changes in pregnancy, such as hemodilution and a mild thrombocytopenia may help to ameliorate the thrombotic diathesis that is
https://www.alpfmedical.info/multiple-myeloma/pregnancy-and-fertility.html
Minimized Cardiopulmonary Bypass Techniques and Technologies by Terence Gourlay | NOOK Book (eBook) | Barnes & Noble®Minimized Cardiopulmonary Bypass Techniques and Technologies by Terence Gourlay | NOOK Book (eBook) | Barnes & Noble®
Traditional cardiopulmonary bypass (CPB) techniques have suffered from a number of disadvantages including haemodilution, inflammation and post-operative
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ZipCombo 12 Place Hematocrit Rotor - LW Scientific
Spin 12 special 40mm hematocrit tubes in the flat12-place flat hematocrit rotor. (Included is one vial of 200 40x0.034mm capillary tubes.)
https://www.lwscientific.com/collections/zipcombo-accessories/products/zipcombo-12-place-hematocrit-rotor
FS PublishersFS Publishers
Ivan Fiodorovich Gorlov, Yuriy Anatolievich Kolosov, Nadezhda Vasilievna Shirokova, Marina Ivanovna Slozhenkina, Natalia Ivanovna Mosolova, Anatoliy Yurievich Kolosov, Lyubov Vladimirovna Getmantseva, Olga Vasilievna Kostyunina, Elena Yurievna Anisimova, Ekaterina Vladimirovna Karpenko, Irina Vladimirovna Yunakova and Anna Vladimirovna Agalakova ...
http://fspublishers.org/IJAB-Papers-Accepted-for-Publication.php
Hold Big Pharma #RxAccountable for Dangerous DrugsHold Big Pharma #RxAccountable for Dangerous Drugs
ANH is launching a campaign and a legal initiative to get dangerous drugs off the market. You can help! Action Alert! Thousands of Americans die every year from…
https://anh-usa.org/hold-big-pharma-rxaccountable-for-dangerous-drugs/?replytocom=57995
what is hematocrit | Answers from Doctors | HealthTapwhat is hematocrit | Answers from Doctors | HealthTap
What is the normal hematocrit for pregnancy? Answered by Dr. Gurmukh Singh: Higher than 36: See this site for more information. http://www.nlm.nih...
https://www.healthtap.com/q/what-is-hematocrit/
Renzo Mazzoleni - Italy <> trap...
He had a hematocrit above 50 before the start of Tre Valli Varesine, 17 August. He was suspended for 15 days. (source: cyclingnews.com ...
http://www.trap-friis.dk/cykling/italy.Mazzoleni-R.htm
Central retinal artery occlusionCentral retinal artery occlusion
Isovolemic hemodilution; Anticoagulation; Dislodging or fragmenting thrombus or embolus; Thrombolysis; and Hyperbaric oxygen. ...
https://en.wikipedia.org/wiki/Central_retinal_artery_occlusion
Patient blood managementPatient blood management
Shander A, Rijhwani TS (December 2004). "Acute normovolemic hemodilution". Transfusion. 44 (12 Suppl): 26S-34S. doi:10.1111/j. ... Another technique, acute normovolemic hemodilution, involves the collection of a selected calculated volume of the patient's ... "Acute Normovolemic Hemodilution Reduces Allogeneic Red Blood Cell Transfusion in Cardiac Surgery: A Systematic Review and Meta- ...
https://en.wikipedia.org/wiki/Patient_blood_management
Diana Beresford-KroegerDiana Beresford-Kroeger
Her thesis was entitled, Myocardial Ischemia and the use of non-typing artificial blood in hemodilution.[citation needed] ... 1984 Oct;62(10):1333-7. Myocardial blood flow and O2-supply following dextran-haemodilution and methaemoglobinaemia in the dog ... Myocardial oxygen-supply during hemodilution with stroma-free hemoglobin and methemoglobin solutions. Biro GP, Beresford- ... hemorheologic changes following acute experimental coronary occlusion and salutary antihyperviscosity effect of hemodilution ...
https://en.wikipedia.org/wiki/Diana_Beresford-Kroeger
Prostate-specific antigenProstate-specific antigen
November 2007). "Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer". JAMA. 298 (19): ...
https://en.wikipedia.org/wiki/Prostate-specific_antigen
Orthogonal polarization spectral imagingOrthogonal polarization spectral imaging
"Validation of OPS imaging for microvascular measurements during isovolumic hemodilution and low hematocrits". Am J Physiol ...
https://en.wikipedia.org/wiki/Orthogonal_polarization_spectral_imaging
Retrograde autologous primingRetrograde autologous priming
However, there are still some studies showing a failure of RAP to limit the hemodilution after the open heart operation. The ... The hemodilution is the primary hematologic interference which results in coagulopathy and decreased capability of carrying ... Although RAP is an effective and safe technique to reduce the hemodilution during CPB, there are still some potential risks of ... Thus, there is a high incidence of distinct degrees of hemodilution with CPB.[citation needed] RAP is a blood conservation ...
https://en.wikipedia.org/wiki/Retrograde_autologous_priming
Intravascular volume statusIntravascular volume status
"Blood Volume Analysis Can Distinguish True Anemica From Hemodilution in Critically Ill Trauma Patients". Western Trauma ...
https://en.wikipedia.org/wiki/Intravascular_volume_status
Wassim Michael HaddadWassim Michael Haddad
Control for Compartmental Systems with Application to Introoperative Anesthesia Influenced by Hemorrhage and Hemodilution ...
https://en.wikipedia.org/wiki/Wassim_Michael_Haddad
HemodynamicsHemodynamics
Clearly, the greater the Hi and the greater the number of units removed during hemodilution, the more effective ANH is for ... During acute normovolemic hemodilution (ANH), blood subsequently lost during surgery contains proportionally fewer red blood ... This is based on the assumption that each unit removed by hemodilution has a volume of 450 mL (the actual volume of a unit will ... can be calculated from the patient's Hi and the final hematocrit after hemodilution(Hm) R C M = E V B × ( H i − H m ) {\ ...
https://en.wikipedia.org/wiki/Hemodynamics
ThromboelastometryThromboelastometry
In reality various effects overlap, including haemodilution or application of high doses of parenteral anticoagulants. High ...
https://en.wikipedia.org/wiki/Thromboelastometry
Deep hypothermic circulatory arrestDeep hypothermic circulatory arrest
Haemodilution, typically to a haematocrit of 20%, is thought to improve flow in the microcirculation. "Cerebral protection and ...
https://en.wikipedia.org/wiki/Deep_hypothermic_circulatory_arrest
Jehovahs Witnesses and blood transfusionsJehovah's Witnesses and blood transfusions
Transfusions of autologous blood part of a "current therapy". Hemodilution, a modified technique in which equipment is arranged ... In 1989, The Watchtower stated, "Each individual must decide" whether to accept hemodilution and autologous blood salvage (cell ... such as hemodilution or cell salvage, are a matter of personal choice, according to what a person's conscience permits. A ...
https://en.wikipedia.org/wiki/Jehovah's_Witnesses_and_blood_transfusions
DextranDextran
The hemodilution caused by volume expansion with dextran use improves blood flow, thus further improving patency of ...
https://en.wikipedia.org/wiki/Dextran
Volume expanderVolume expander
... this parameter is decreased by crystalloids due to hemodilution. Therefore, they should theoretically preferentially increase ...
https://en.wikipedia.org/wiki/Volume_expander
Intravenous therapyIntravenous therapy
... this parameter is decreased by crystalloids due to hemodilution. Crystalloids generally are much cheaper than colloids. Buffer ...
https://en.wikipedia.org/wiki/Intravenous_therapy
Cardiothoracic surgeryCardiothoracic surgery
Nazih Zuhdi performed the first total intentional hemodilution open heart surgery on Terry Gene Nix, age 7, on February 25, ... using the total intentional hemodilution machine. In 1985 Zuhdi performed Oklahoma's first successful heart transplant on Nancy ...
https://en.wikipedia.org/wiki/Cardiothoracic_surgery
Cardiac surgeryCardiac surgery
Nazih Zuhdi performed the first total intentional hemodilution open-heart surgery on Terry Gene Nix, age 7, on 25 February 1960 ... using the total intentional hemodilution machine. In the early 1990s, surgeons began to perform off-pump coronary artery bypass ...
https://en.wikipedia.org/wiki/Cardiac_surgery
HemoglobinHemoglobin
... can be tracked noninvasively, to build an individual data set tracking the hemoconcentration and hemodilution ...
https://en.wikipedia.org/wiki/Hemoglobin
Subarachnoid hemorrhageSubarachnoid hemorrhage
... and hemodilution (mild dilution of the blood). Evidence for this approach is inconclusive; no randomized controlled trials have ...
https://en.wikipedia.org/wiki/Subarachnoid_hemorrhage
Bloodless surgeryBloodless surgery
Many doctors view acute normovolemic hemodilution, a form of storage of a patient's own blood, as a pillar of "bloodless ...
https://en.wikipedia.org/wiki/Bloodless_surgery
DilutionDilution
Hemodilution, in blood Dilation (disambiguation) This disambiguation page lists articles associated with the title Dilution. If ...
https://en.wikipedia.org/wiki/Dilution
SaprolegniaSaprolegnia
A Saprolegnia infection is usually fatal, eventually causing hemodilution, though the time to death varies depending on the ...
https://en.wikipedia.org/wiki/Saprolegnia
PerfusionistPerfusionist
... and hemodilution. Sometimes, perfusionists are granted administrative tasks such as purchasing supplies or equipment, as well ...
https://en.wikipedia.org/wiki/Perfusionist
Human serum albuminHuman serum albumin
... hemodilution [as in pregnancy], increased vascular permeability or decreased lymphatic clearance) Acute disease states ( ...
https://en.wikipedia.org/wiki/Human_serum_albumin
Jehovahs WitnessesJehovah's Witnesses
... hemodilution Archived September 7, 2008, at the Wayback Machine, heart lung machine, dialysis, epidural blood patch Archived ...
https://en.wikipedia.org/wiki/Jehovah's_Witnesses
Andre Francis PalmerAndre Francis Palmer
"Hemodynamics and tissue oxygenation after hemodilution with ultrahigh molecular weight polymerized albumin" Minerva ...
https://en.wikipedia.org/wiki/Andre_Francis_Palmer
Platelet-rich plasmaPlatelet-rich plasma
Ferrari M, Zia S, Valbonesi M, Henriquet F, Venere G, Spagnolo S, Grasso MA, Panzani I. A new technique for hemodilution, ...
https://en.wikipedia.org/wiki/Platelet-rich_plasma
Triple H (disambiguation)Triple H (disambiguation)
... and hemodilution Triple H syndrome, a urea-cycle disorder Search for "triple-h" on Wikipedia. HHH (disambiguation) 3H ( ...
https://en.wikipedia.org/wiki/Triple_H_(disambiguation)
Intraoperative blood salvageIntraoperative blood salvage
Acute normovolemic hemodilution (ANH) is a form of autologous transfusion where whole blood is collected from a patient at the ...
https://en.wikipedia.org/wiki/Intraoperative_blood_salvage
Hypovolemic shockHypovolemic shock
The simultaneous loss of coagulation factors via hemorrhage, hemodilution with resuscitation fluids, and coagulation cascade ...
https://en.wikipedia.org/wiki/Hypovolemic_shock
A feasibility and safety study of intracoronary hemodilution during primary coronary angioplasty in order to reduce reperfusion...A feasibility and safety study of intracoronary hemodilution during primary coronary angioplasty in order to reduce reperfusion...
Transcatheter intracoronary hemodilution with room temperature perfusate during PPCI is feasible and appears safe. Such a ... A feasibility and safety study of intracoronary hemodilution during primary coronary angioplasty in order to reduce reperfusion ... Conclusions: Transcatheter intracoronary hemodilution with room temperature perfusate during PPCI is feasible and appears safe ... designed a pilot study to evaluate safety and feasibility of an inexpensive and simple approach to intracoronary hemodilution ...
https://pubmed.ncbi.nlm.nih.gov/28636165/
Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass... | Archive ouverte...Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass... | Archive ouverte...
Aged - Coronary Artery Bypass/adverse effects - Female - Heart Diseases/etiology/prevention & control - Hemodilution/methods - ... LICKER, Marc et al. Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass ... Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass surgery. ... We hypothesized that lowering blood viscosity with acute normovolemic hemodilution (ANH) would confer additional ...
https://archive-ouverte.unige.ch/unige:39926
Hypoalbuminemia: Background, Pathophysiology, EtiologyHypoalbuminemia: Background, Pathophysiology, Etiology
Hemodilution. In the presence of ascites from any cause, the serum albumin level is not a good index of the residual synthetic ...
https://www.medscape.com/answers/166724-41448/what-is-the-physiology-of-albumin-degradation
The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: Results of a randomized trial in infants<...
The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: Results of a randomized trial in infants. ... Conclusions: Hemodilution to a hematocrit level in wide use for cardiopulmonary bypass and thought to be safe is associated ... Conclusions: Hemodilution to a hematocrit level in wide use for cardiopulmonary bypass and thought to be safe is associated ... Conclusions: Hemodilution to a hematocrit level in wide use for cardiopulmonary bypass and thought to be safe is associated ...
https://mayoclinic.pure.elsevier.com/en/publications/the-influence-of-hemodilution-on-outcome-after-hypothermic-cardio
IMSEAR at SEARO: Preoperative autologous blood collection and haemodilution with dextran.
After the end of haemodilution, another blood samples (as study samples) were once collected for analysis. Haematocrit, ... In conclusion, the autologous blood collection and haemodilution technique was suitable and possibly practical in ever elective ... Preoperative autologous blood collection and haemodilution with dextran.. Authors: Vichitvejpaisal, Phongthara. ... Preoperative autologous blood collection and haemodilution with dextran. Siriraj Medical Journal, 1991 Mar; 43(3): 155-159. ...
https://imsear.searo.who.int/handle/123456789/138101
Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer<...
Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer. In: Journal of the American Medical ... Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer. Journal of the American Medical ... Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer. / Bañez, Lionel L.; Hamilton, Robert ... Dive into the research topics of Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer. ...
https://augusta.pure.elsevier.com/en/publications/obesity-related-plasma-hemodilution-and-psa-concentration-among-m
Dont Be A Victim Of Hemodilution!! - Hinerman GroupDon't Be A Victim Of Hemodilution!! - Hinerman Group
Dont Be A Victim Of Hemodilution!! - Hinerman Group, High Risk Life Insurance Quotes You Can Trust. ... Home » Life Insurance Blog » Dont Be A Victim Of Hemodilution!!. Dont Be A Victim Of Hemodilution!!. by Ed Hinerman , Nov 21 ... If the theory of hemodilution is correct, obese men are at risk of not having prostate cancer detected as early as their ... is that obesity can make early detection of prostate cancer harder due to a process called hemodilution [...] ...
https://hinermangroup.com/dont-be-a-victim-of-hemodilution/
Bloodless Heart Surgery: Types, Benefits, Conditions - UChicago MedicineBloodless Heart Surgery: Types, Benefits, Conditions - UChicago Medicine
Hemodilution: Before surgery a particular amount of concentrated blood is drawn from the patient and the same amount of fluid ...
https://uchicagokidshospital.org/conditions-services/heart-vascular/heart-surgery/bloodless-heart-surgery
Splenomegaly Workup: Approach Considerations, Findings in Hypersplenism, Splenectomy and Splenic BiopsySplenomegaly Workup: Approach Considerations, Findings in Hypersplenism, Splenectomy and Splenic Biopsy
Anemia - The anemia observed in splenomegaly results from sequestration and hemodilution. * Leukopenia - Increased destruction ...
https://emedicine.medscape.com/article/206208-workup
Transfusion and Autotransfusion: Overview, Indications, Component TransfusionTransfusion and Autotransfusion: Overview, Indications, Component Transfusion
Autologous (acute) normovolemic hemodilution. This technique involves collecting a patients blood (2-4 units) into ... The evidence on the overall efficacy of autologous normovolemic hemodilution is conflicting with respect to blood savings and ... What is autologous (acute) normovolemic hemodilution?. What are the disadvantages of preoperative autologous donation for ... Segal JB, Blasco-Colmenares E, Norris EJ, Guallar E. Preoperative acute normovolemic hemodilution: a meta-analysis. Transfusion ...
https://reference.medscape.com/article/434176-overview
Thrombocytopenia: MedlinePlus Medical EncyclopediaThrombocytopenia: MedlinePlus Medical Encyclopedia
Thrombocytopenia caused by platelet destruction, hypersplenism, or hemodilution. In: Hoffman R, Benz EJ, Silberstein LE, et al ...
https://medlineplus.gov/ency/article/000586.htm
Treatment of refractory angina in patients not suitable for revascularization | Nature Reviews CardiologyTreatment of refractory angina in patients not suitable for revascularization | Nature Reviews Cardiology
Long-term urokinase therapy and isovolemic hemodilution: a clinical and hemodynamic comparison in patients with refractory ...
https://www.nature.com/articles/nrcardio.2013.200?error=cookies_not_supported&code=561428b2-dff7-4b1e-8732-5be1e25d7b73
The Next Generation of Colloids: Ready for Prime Time? : Anesthesia & AnalgesiaThe Next Generation of Colloids: Ready for "Prime Time"? : Anesthesia & Analgesia
Hemodilution and priming solutions. In: Gravlee G, Davis R, Stammers A, Ungerleider R, eds. Cardiopulmonary bypass principles ... Adjunct techniques-hemodilution. In: Peirce EC, ed. Extracorporeal circulation for open-heart surgery: pathophysiology, ... Cooper JR Jr, Slogoff S. Hemodilution and priming solutions for cardiopulmonary bypass. In: Gravlee GP, Davis RF, Stammers AH, ... along with concerns about the high viscosity of the resultant CPB prime solution led to experiments with hemodilution and ...
https://journals.lww.com/anesthesia-analgesia/Fulltext/2009/12000/The_Next_Generation_of_Colloids__Ready_for__Prime.1.aspx
Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)
Categories: Hemodilution Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 2 ...
https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Hemodilution&parentid=25440&catid=12544
Effects of acute normovolemic hemodilution on post-cardiopulmonary bypass coagulation tests and allogeneic blood transfusion in...Effects of acute normovolemic hemodilution on post-cardiopulmonary bypass coagulation tests and allogeneic blood transfusion in...
Acute normovolemic hemodilution (ANH) is a blood conservation strategy associated with variable success, and rarely studied in ... Effects of acute normovolemic hemodilution on post-cardiopulmonary bypass coagulation tests and allogeneic blood transfusion in ...
http://dgivan.dental.uab.edu/display/pub2467075
Glossary | SABMGlossary | SABM
Acute Normovolemic Hemodilution (ANH). Acute Normovolemic Hemodilution (ANH) During surgery, blood is diverted to bags and ...
https://sabm.org/glossary/
Gestational ThrombocytopeniaGestational Thrombocytopenia
This page includes the following topics and synonyms: Gestational Thrombocytopenia.
https://fpnotebook.com/hemeonc/OB/GstnlThrmbcytpn.htm
Free Nursing Flashcards about pediatric hema disoFree Nursing Flashcards about pediatric hema diso
Prevention = maintaining hemodilution. Medical management is supportive and symptomatic. Rest. Hydration. Electrolyte ...
https://www.studystack.com/flashcard-822983
Plasbumin 5 (Albumin) | RxMed: Diseases and Preparations DescriptionPlasbumin 5 (Albumin) | RxMed: Diseases and Preparations' Description
In patients with a normal blood volume, hemodilution lasts for a much shorter period. The rapid rise in blood pressure, which ... When circulating blood volume has been reduced, hemodilution following the administration of albumin persists for many hours. ... of albumin should be supplemented by the transfusion of whole blood to treat the relative anemia associated with hemodilution. ...
https://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/cps-_monographs/CPS-_
Are agents affecting platelet functions clinically useful? - The American Journal of Medicine
in: Intentional Hemodilution. Bibl Haematol. 41. 1975: 98. *Google Scholar. **Lambie J.M. ...
https://www.amjmed.com/article/0002-9343
Nursing 334 FlashcardsNursing 334 Flashcards
hemodilution is called?. Definition. pseudoanemia. Hgb ,11, Hematocrit ,30%. Term. BP in 2nd trimester _____, then returns to ...
https://www.flashcardmachine.com/nursing-334.html
Platelet antibodies blood testPlatelet antibodies blood test
Thrombocytopenia caused by platelet destruction, hypersplenism, or hemodilution. In: Hoffman R, Benz EJ, Silberstein LE, et al ...
https://www.ucsfhealth.org/medical-tests/platelet-antibodies-blood-test
SciELO - Brazil - Physiological response and performance of tambaqui fed with diets supplemented with Amazonian nut...SciELO - Brazil - Physiological response and performance of tambaqui fed with diets supplemented with Amazonian nut...
... hemoglobin synthesis inhibition and the competition for the oxygen binding site can cause a hemodilution or anemia in fish, ... These parameters can indicate hemoconcentration or hemodilution. Hemoconcentration may be a strategy to increase oxygen ...
https://www.scielo.br/j/cr/a/TNfL4km8VbRsNjyfn3MCFJf/?lang=en
Nitrate/Nitrite Toxicity: Literature Cited | Environmental Medicine | ATSDRNitrate/Nitrite Toxicity: Literature Cited | Environmental Medicine | ATSDR
... of noninvasive and continuous total hemoglobin measurement by pulse CO-Oximetry in human subjects undergoing hemodilution. ...
https://www.atsdr.cdc.gov/csem/nitrate-nitrite/literature.html
Home - Professor Roger GreenhalghHome - Professor Roger Greenhalgh
Post operative deep vein thrombosis, an association with haemodilution. Br J Surg 1978: 68, 825 ...
https://www.imperial.ac.uk/people/r.greenhalgh/?respub-action=citation.html&id=359710&noscript=noscript
The β2-adrenergic receptor antagonist ICI-118,551 blocks the constitutively activated HIF signalling in hemangioblastomas from...The β2-adrenergic receptor antagonist ICI-118,551 blocks the constitutively activated HIF signalling in hemangioblastomas from...
Beta2 adrenergic antagonist inhibits cerebral cortical oxygen delivery after severe haemodilution in rats. Br J Anaesth. 97(5 ...
https://www.nature.com/articles/s41598-019-46448-6?error=cookies_not_supported&code=00eb8d82-b1b2-476a-a25f-2aaf2ed5ea8b
Quintessence PublishingQuintessence Publishing
3 . Hemodilution in orthognathic surgery Authors: Partnoy/Fridrich/Buckley/Murray Abstract 4 . Video imaging: techniques for ...
http://www.quintpub.com/journals/aoos/journal_abstracts.php?name_abbr=IJAOOS&volume_num=5&iss_num=4&vol_year=1990
Acute normovolemicPreoperativeAutologousSalvagePlateletAnemiaObesePregnancyMethodsReperfusionObesityMechanismEffectsStudyPatientsLevelNormovolaemic haemodilutionHomologous blood transfusionNormovolemic hemodilution in patientsHypervolemiaIsovolemic hemodilutionHypothermiaMyocardial IschemiaIsovolumicHematocritPreoperativeHemoglobinAortic surgeryThrombocytopeniaPerfusionIntraoperativeDecreaseSalineHypertensionFluidOccurSurgicalModerateHemorrhageCardiacEffectResultsSurgeryVolumeClinicalMechanismsStateAlter
Acute normovolemic3
  • Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass. (unige.ch)
  • We hypothesized that lowering blood viscosity with acute normovolemic hemodilution (ANH) would confer additional cardioprotection in patients undergoing coronary artery bypass surgery (CABG) with aortic cross-clamping. (unige.ch)
  • Acute normovolemic hemodilution (ANH) is a blood conservation strategy associated with variable success, and rarely studied in more complex cardiac procedures. (uab.edu)
Preoperative1
  • IMSEAR at SEARO: Preoperative autologous blood collection and haemodilution with dextran. (who.int)
Autologous2
  • In conclusion, the autologous blood collection and haemodilution technique was suitable and possibly practical in ever elective surgical patients without any undesirable side effects. (who.int)
  • Processes include autologous hemodilution and cell salvage , and treating or averting anemia pre- and post-surgery. (hopkinsmedicine.org)
Salvage1
  • Intraoperative blood conservation techniques can be utilized with either use of hemodilution or blood salvage with recirculation methods to minimize need for other forms of blood replacement. (rchsd.org)
Platelet1
  • Thrombocytopenia caused by platelet destruction, hypersplenism, or hemodilution. (medlineplus.gov)
Anemia1
  • Anemia - The anemia observed in splenomegaly results from sequestration and hemodilution. (medscape.com)
Obese4
  • Because men with higher body mass index (BMI) have greater circulating plasma volumes, lower PSA concentrations among obese men may be due to hemodilution. (elsevier.com)
  • Objective: To determine the association between hemodilution and PSA concentration in obese men with prostate cancer. (elsevier.com)
  • hemodilution may therefore be responsible for the lower serum PSA concentrations among obese men with prostate cancer. (elsevier.com)
  • If the theory of hemodilution is correct, obese men are at risk of not having prostate cancer detected as early as their smaller counterparts. (hinermangroup.com)
Pregnancy3
  • With normal pregnancy, blood volume increases, which results in a concomitant hemodilution. (medscape.com)
  • Total calcium level decreases during pregnancy, due to hemodilution, while the ionized calcium level remains stable [2 ]. (who.int)
  • Meanwhile, physiological hemodilution carries in pregnancy an important adaptive function. (iospress.com)
Methods1
  • Methods: In a single-center randomized trial with blinded assessment of outcomes, we compared use of 2 hemodilution protocols during hypothermic cardiopulmonary bypass with infant cardiac surgery. (elsevier.com)
Reperfusion2
  • We designed a pilot study to evaluate safety and feasibility of an inexpensive and simple approach to intracoronary hemodilution during primary angioplasty (PPCI) to reduce reperfusion injury. (nih.gov)
  • The underlying mechanism is likely to be multifactorial, involving operative trauma, hemodilution and endothelial damage by edema, ischemia/reperfusion of organs, and contact-activation of blood components during ECC [ 2 , 3 ]. (hindawi.com)
Obesity1
  • Obesity is associated with a hemodilution of PSA, therefore decreasing the risk of referral for biopsy," he said. (renalandurologynews.com)
Mechanism1
  • Under these conditions, moderate hemodilution is an effective mechanism for preventing the development of severe disseminated intravascular coagulation (DIC) in labor, during surgery, in various forms of obstetric pathology. (iospress.com)
Effects1
  • Dextrans cause a hypervolemic hemodilution and affect factor VIII, with both these effects influencing blood flow. (medscape.com)
Study1
  • After the end of haemodilution, another blood samples (as study samples) were once collected for analysis. (who.int)
Patients1
  • Haemodilution is common in patients with advanced heart failure // Circulation. (medline.ru)
Level1
  • Conclusions: Hemodilution to a hematocrit level in wide use for cardiopulmonary bypass and thought to be safe is associated with adverse perioperative and developmental outcomes in infants. (elsevier.com)
Normovolaemic haemodilution2
  • Acute normovolaemic haemodilution - an old, outdated friend? (nataonline.com)
  • After ineffective conservative treatement including plasmaexpander such as Hydroxyaethylstarch or others, normovolaemic haemodilution, cortisone and oral haemo-rheological substances, HBOT is effective in 50% of the cases to reduce hearing loss by 20 dB or more. (hyperbaricoxygentherapy.com)
Homologous blood transfusion2
  • 16. [Extreme normovolemic hemodilution as homologous blood saving measure in refusal of homologous blood transfusion]. (nih.gov)
  • Effect of an homologous blood transfusion and hemodilution on the central hemodynamics and myocardial contractile function]. (doximity.com)
Normovolemic hemodilution in patients1
  • 2. [Hemodynamics in controlled normovolemic hemodilution in patients with obliterative vascular diseases]. (nih.gov)
Hypervolemia3
  • Use with caution in conditions where hypervolemia and its consequences or hemodilution could represent a special risk to the patient. (nih.gov)
  • Induced hypertension, hypervolemia, and hemodilution (ie, "triple-H therapy") aimed to maintain adequate cerebral perfusion pressure in the setting of impaired cerebrovascular autoregulation. (medscape.com)
  • Hypervolemia: Use with caution in patients who are at risk of hypervolemia or hemodilution. (nih.gov)
Isovolemic hemodilution2
  • 8. [Isovolemic hemodilution in coronary heart disease--clinical and hemodynamic effects]. (nih.gov)
  • 18. Isovolemic hemodilution alters the ratio of whole-body to large-vessel hematocrit (F-cell ratio). (nih.gov)
Hypothermia2
  • 50-52 Although hemodilution increases cerebral blood flow, 53 it may limit oxygen delivery by reducing the oxygen carrying capacity of blood, in the setting of the leftward shift of oxyhemoglobin dissociation induced by hypothermia. (firebaseapp.com)
  • IV infusion of chilled saline, while shown to be effective in many cases, has numerous side effects, including hemodilution, potential fluid overload in patients with heart failure, coagulopathy, increased infection rates, reduced drug effectiveness, and excessive patient hypothermia that can result in shivering and potential re-arrest. (jems.com)
Myocardial Ischemia1
  • The higher heart rates that developed during hemodilution may have contributed to the development of an imbalance between myocardial supply and demand resulting in ECG evidence of myocardial ischemia. (aku.edu)
Isovolumic4
  • We conducted two separate protocols utilizing intravenous infusion of a nitric oxide synthase inhibitor and isovolumic haemodilution to assess the influence of nitric oxide on neurovascular coupling in humans. (southwales.ac.uk)
  • Isovolumic haemodilution did not alter neurovascular coupling. (southwales.ac.uk)
  • 2) NVC was assessed prior to and following isovolumic haemodilution, whereby 20% of whole blood was removed and replaced with 5% human serum albumin to reduce haemoglobin concentration (n = 8). (southwales.ac.uk)
  • n = 6, aged 39 ± 17 yr), before and during isovolumic hemodilution with room air and hyperoxia (end-tidal Po2 = 100 mmHg). (cardiffmet.ac.uk)
Hematocrit2
  • Also you can check the serial results for Na, Hb Hemodilution during cardiopulmonary bypass is currently almost universal for cardiopulmonary bypass, but the minimum safe hematocrit has been controversial. (firebaseapp.com)
  • Hemodilution uses the ideal blood volume and serial hematocrit measures drawn before and after administration of a known quantity of IV fluid to estimate blood volume. (firebaseapp.com)
Preoperative2
  • 7. Effects of a hemoglobin-based oxygen carrier (HBOC-201) on hemodynamics and oxygen transport in patients undergoing preoperative hemodilution for elective abdominal aortic surgery. (nih.gov)
  • 12. [Effect of acute preoperative hemodilution on circulation, oxygen budget and blood coagulation]. (nih.gov)
Hemoglobin2
  • Masimo has announced the findings of an abstract that compared Masimo noninvasive and continuous hemoglobin (SpHb) to intermittent and invasive lab hemoglobin (LabHb) in reflecting iatrogenic hemodilution during incremental fluid administration of patients undergoing major surgery. (mpo-mag.com)
  • Our study also demonstrates that continuous monitoring of hemoglobin (SpHb) through Masimo Pulse CO-Oximetry sensors may detect the development of such iatrogenic hemodilution in real time. (mpo-mag.com)
Aortic surgery1
  • Our hypothesis is that the use of the RAP method in aortic surgery may result in a limitation of hemodilution and a decrease in fHb levels. (annals.in)
Thrombocytopenia1
  • Thrombocytopenia caused by platelet destruction, hypersplenism, or hemodilution. (medlineplus.gov)
Perfusion2
  • The goal of optimized perfusion is to minimize the impact of CPB on patient outcomes by reducing hemodilution and blood contact surface area, minimizing GME and improving biocompatibility, while providing high performance. (livanova.com)
  • The difficulty off ECC government are aggravated by the possible lack of EBM-centered requirements covering basic haemodynamic parameters, i.e., pump disperse rates and you may perfusion pressure, also haemodilution variety otherwise evidence on vasoconstrictors have fun with. (rasam-polymer.ir)
Intraoperative1
  • Case report: intraoperative management of extreme hemodilution in a patient with a severed axillary artery. (bloodless.com.br)
Decrease4
  • The researchers concluded, "Fluid loading as part of goal-directed therapy may cause a paradoxical decrease in DO 2 due to the development of iatrogenic hemodilution. (mpo-mag.com)
  • The development of iatrogenic hemodilution is reflected by a real-time decrease in the SpHb trend, which is similar to the intermittent LabHb trend. (mpo-mag.com)
  • 1. Bubenek S, Valeanu L, Popescu M, Cacoveanu M, Tomescu D, and Perel A. Optimization of cardiac output by incremental fluid administration is associated with iatrogenic hemodilution and a paradoxical decrease in oxygen delivery. (mpo-mag.com)
  • This pioneer study allows us to understand that iron supplementation may not be needed as any decrease is due to physiological haemodilution. (who.int)
Saline1
  • Conclusions This study provides new insight into the effects of haemodilution by isotonic saline on clotting time (TGP), clot strength (G′GP) and clot microstructure (df). (cardiffmet.ac.uk)
Hypertension1
  • the importance of treatment with calcium antagonists, hypervolaemic haemodilution, and induced arterial hypertension is discussed in light of the current literature. (nih.gov)
Fluid2
  • In the study, Dr. Azriel Perel, Dr. Serban Bubenek, and colleagues at the Emergency Institute for Cardiovascular Diseases in Bucharest examined the effects of incremental fluid loading on oxygen delivery and on LabHb and SpHb as markers of possible iatrogenic hemodilution, which can necessitate blood transfusions that might otherwise be avoided. (mpo-mag.com)
  • This is generally due to haemodilution from fluid resuscitation. (minivetguide.com)
Occur1
  • However, one should note it can also occur as the result of haemodilution. (minivetguide.com)
Surgical1
  • 14. [Normovolemic hemodilution during surgical revascularization of the myocardium]. (nih.gov)
Moderate1
  • Note the moderate to marked haemodilution and overall low cellularity. (avd.asia)
Hemorrhage1
  • 7. Johnson D, Agee S, Reed A, Gegel B, Burgert J, Gasko J, Loughren M. The effects of QuikClot Combat Gauze on hemorrhage control in the presence of hemodilution. (quikclot.com)
Cardiac1
  • In Andeans with EE at 4,340 m, hemodilution lowered PVR in room air (2.9 ± 0.9 vs. 2.3 ± 0.8 wu, P = 0.03), but PASP remained unchanged (31.3 ± 6.7 vs. 30.9 ± 6.9 mmHg, P = 0.80) due to an increase in cardiac output. (cardiffmet.ac.uk)
Effect3
  • We investigated the effect of progressive haemodilution on the dynamics of fibrin clot formation and clot microstructure using a novel rheological method. (cardiffmet.ac.uk)
  • The changes concerning the plasmatic volume and hemodilution occurred in M1, confirming its immediate effect. (bvsalud.org)
  • The generation and formation rates were based on the measured levels of activation markers, clearance rates and effect of hemodilution on marker levels. (houstonmethodist.org)
Results1
  • Doppler ultrasound results of hemodilution treatment]. (dbcls.jp)
Surgery3
  • The mean duration of the surgery in the hemodilution group was longer. (scielo.br)
  • The number of levels submitted to surgery ranged from 7 to 16 in the hemodilution group, and from 4 to 13 in the control group. (scielo.br)
  • It is common to have a mild anaemia post-surgery, due to a combination of blood loss and haemodilution. (minivetguide.com)
Volume3
  • 9. [Gelatin for volume replacement in hemodilution: hemodynamic study]. (nih.gov)
  • In hemodilution, blood is diverted from the body, replaced with a volume expander, and later returned to the patient. (kamna-lechnyr.cz)
  • By focusing on a new attribute, the oxygenator system dynamic operating volume (DOV), the Inspire family minimizes the overall impact on hemodilution. (livanova.com)
Clinical1
  • Minimizing hemodilution contributes to decreased blood transfusions and improved clinical outcomes during and after cardiopulmonary bypass (CPB). (livanova.com)
Mechanisms1
  • 5. [The mechanisms of hemodynamic shifts in normovolemic hemodilution]. (nih.gov)
State1
  • Haemodilution-induced profibrinolytic state is mitigated by fresh-frozen plasma: implications for early haemostatic intervention in massive haemorrhage. (edu.pl)
Alter1
  • In contrast, after acclimation to 5,050 m, hemodilution did not significantly alter PASP (22.7 ± 5.2 vs. 24.5 ± 5.2 mmHg, P = 0.14) or PVR (2.2 ± 0.9 vs. 2.3 ± 1.2 wu, P = 0.77), although both remained sensitive to additional acute hypoxia. (cardiffmet.ac.uk)
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