The simultaneous, or near simultaneous, transference of heart and lungs from one human or animal to another.
The transference of either one or both of the lungs from one human or animal to another.
Inflammation of the BRONCHIOLES leading to an obstructive lung disease. Bronchioles are characterized by fibrous granulation tissue with bronchial exudates in the lumens. Clinical features include a nonproductive cough and DYSPNEA.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
The transference of a part of or an entire liver from one human or animal to another.
Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.
A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
The hollow, muscular organ that maintains the circulation of the blood.
An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.
The transference of a heart from one human or animal to another.
The transference of a kidney from one human or animal to another.
Pathological processes involving any part of the LUNG.
The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.
Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.
Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.
Transplantation of an individual's own tissue from one site to another site.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.
Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
Radiography of blood vessels after injection of a contrast medium.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
The ratio of alveolar ventilation to simultaneous alveolar capillary blood flow in any part of the lung. (Stedman, 25th ed)
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in cardiovascular and cerebral circulation.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in the gastrointestinal system, cardiovascular and cerebral circulation, brain, thyroid, and joints.

Pulmonary ischemia/reperfusion injury: a quantitative study of structure and function in isolated heart-lungs of the rat. (1/140)

Early graft dysfunction after lung transplantation is a significant and unpredictable problem. Our study aimed at a detailed investigation of structure-function correlations in a rat isolated heart-lung model ofischemia/ reperfusion injury. Variable degrees of injury were induced by preservation with potassium-modified Euro-Collins solutions, 2 hr of cold ischemia, and 40 min of reperfusion. Pulmonary artery pressure (Ppa), pulmonary vascular resistance (PVR), peak inspiratory pressure (PIP), and perfusate gases (deltaPO2, deltaPCO2) were recorded during reperfusion. Right lungs were used to calculate W/D-weight ratios. Nineteen experimental and six control left lungs were fixed for light and electron microscopy by vascular perfusion. Systematic random samples were analyzed by stereology to determine absolute and relative volumes of lung structures, the amount of interstitial and intraalveolar edema, and the extent of epithelial injury. Lectin- and immunohistochemistry using established epithelial cell markers were performed in three animals per group to reveal sites of severe focal damage. Experimental lungs showed a wide range in severity of ischemia/ reperfusion injury. Intraalveolar edema fluid amounted to 77-909 mm3 with a mean of 448+/-250 mm3 as compared with 22+/-22 mm3 in control lungs (P<0.001). Perfusate oxygenation (deltaPO2) decreased from 30.5+/-15.2 to 21.7+/-15.2 mm Hg (P=0.05) recorded after 5 and 40 minutes of reperfusion. In experimental lungs, a surface fraction of 1% to 58% of total type I pneumocyte surface was damaged. Intraalveolar edema per gas exchange region (Vv ape,P) and deltaPO2 were related according to deltaPO2 = 96 - 60 x log10(Vv ape,P) [mm Hg]. The extent of epithelial injury did not correlate with deltaPO2 nor with intraalveolar edema, but increased significantly with PVR. Lectin- and immunohistochemistry revealed focal severe damage to the alveolar epithelium at the border of perivascular cuffs.  (+info)

The porcine bronchial artery. Anastomoses with oesophageal, coronary and intercostal arteries. (2/140)

Information about the existence and anatomy of arterial anastomoses with the porcine bronchial artery is lacking in the literature. Prior to basic physiological investigations in a porcine model related to lung transplantation with bronchial artery revascularisation, this study was designed to examine the anatomy of systemic arterial anastomoses with the bronchial artery system. Twenty pigs were studied in 3 groups. In 2 groups the heart-lung block was removed with all mediastinal structures. One group served for investigation of coronary-bronchial artery anastomoses and one for investigation of oesophageal-bronchial artery anastomoses. The systemic arteries to be examined were cannulated. The inflated heart-lung block was examined macroscopically with Evans blue, and radiographically after contrast injection. In the 3rd group intercostobronchial artery anastomoses were studied radiographically with the heart-lung block in situ. Coronary-bronchial artery anastomoses were demonstrated in 3 of the 5 pigs with an aortic 'pouch' technique, but contrast was very limited in 2 of these 3. Oesophageal arterial anastomoses with bronchial arterial branches and/or the pulmonary veins were demonstrated in 6 of the 7 pigs and more markedly than the coronary-bronchial anastomoses. Intercostobronchial artery anastomoses could not be demonstrated angiographically. It was concluded that the existence of coronary-bronchial and oesophageal-bronchial artery anastomoses in the pig appear to establish an arterial net between the base of the heart and the distal oesophagus. The resemblance to human oesophageal-bronchial artery anastomoses supports use of a porcine model for experimental studies.  (+info)

The history and development of cardiac transplantation. (3/140)

The history of heart surgery, spanning only 100 years to date, has seen some of the most daring and persistent men and women in all of medical history. Many aspects of heart surgery, including such innovations as the heart-lung machine, aortic aneurysm surgery, and the correction of congenital heart defects, have provided future surgeons with an important lesson: diligent research can solve complex problems. The history and development of cardiac transplantation is particularly full of challenges that have been overcome, with the research phase alone spanning more than 90 years. During that time, essential contributions came from all over the world, including the United States, Russia, England, and South Africa. As is typical of medical advancement, individual contributions did not stand alone but added to the experience of those who had come before. Even so, the work of a few particular groups deserves special recognition. Most notable is the Stanford team, led by Dr. Norman Shumway, who continued to transplant human hearts when other institutions had abandoned hopes for the operation. Largely because of the commitment of that team, cardiac transplantation has become a standard option in the treatment of end-stage heart disease. Currently, only the availability of donor hearts limits the number of cardiac transplantations performed worldwide.  (+info)

Haemodynamic response to dynamic exercise after heart-lung transplantation. (4/140)

The purpose of this study was to investigate the haemodynamic response to dynamic exercise after heart-lung transplantation (HLT). Nine stable HLT recipients (6 males) were studied 12-55 months after transplantation. While sitting on a cycle ergometer, they first underwent a maximal symptom-limited exercise test (power increment was 10 W x min(-1)) to determine the maximal tolerable workload. On the next day, they performed a second exercise test at 0, 40, 60 and 80% of their predetermined maximal workload (mean+/-sD: 108+/-20 W). Stage duration was 6 min. Respiratory, gas exchange, and haemodynamic measurements were performed at rest, during the last minute of each stage, and after recovery. Haemodynamic variables at rest were within normal limits except heart rate (HR) which was greater and stroke volume index (SVI) which was lower than normal. Peak oxygen consumption was 61+/-8% of predicted. HR showed an initial slow increase followed by a steeper rise, and a delayed return to baseline during the recovery period. SVI and cardiac index (CI) increased at the onset of exercise but did not change significantly at 40-80% of the maximal workload. Pulmonary capillary wedge pressure increased from 4+/-2 mmHg at rest to 14+/-3 mmHg at maximal exercise. It is concluded that during dynamic exercise, heart-lung transplantation recipients demonstrate a chronotropic incompetence, a reduced increase in cardiac index and stroke volume index, and an excessive rise in left ventricular filling pressures. These alterations may contribute to the persistent exercise limitation.  (+info)

Vagal feedback in the entrainment of respiration to mechanical ventilation in sleeping humans. (5/140)

We studied the capacity of four "normal" and six lung transplant subjects to entrain neural respiratory activity to mechanical ventilation. Two transplant subjects were studied during wakefulness and demonstrated entrainment indistinguishable from that of normal awake subjects. We studied four normal subjects and four lung transplant subjects during non-rapid eye movement (NREM) sleep. Normal subjects entrained to mechanical ventilation over a range of ventilator frequencies that were within +/-3-5 breaths of the spontaneous respiratory rate of each subject. After lung transplantation, during which the vagi were cut, subjects did demonstrate entrainment during NREM sleep; however, entrainment only occurred at ventilator frequencies at or above each subject's spontaneous respiratory rate, and entrainment was less effective. We conclude that there is no absolute requirement for vagal feedback to induce entrainment in subjects, which is in striking contrast to anesthetized animals in which vagotomy uniformly abolishes entrainment. On the other hand, vagal feedback clearly enhances the fidelity of entrainment and extends the range of mechanical frequencies over which entrainment can occur.  (+info)

Cyclosporine metabolism in patients after kidney, bone marrow, heart-lung, and liver transplantation in the early and late posttransplant periods. (6/140)

Cyclosporine is used in the prevention of allograft rejection. Owing to its narrow therapeutic index, regular monitoring of the whole blood levels of cyclosporine is required. We observed that immunoassays measured significantly higher cyclosporine levels than did high-performance liquid chromatography (HPLC) over time after transplantation. As cyclosporine metabolites cross-react even with immunoassays, this observation might be due to alterations of the cyclosporine metabolism. We analyzed cyclosporine metabolite concentrations in the early and in the late posttransplantation periods in 127 patients after kidney, bone marrow, heart-lung, and liver transplantation by HPLC and determined whole blood levels of cyclosporine by 4 immunoassays (enzyme-multiplied immunoassay [EMIT], cloned enzyme donor immunoassay [CEDIA], AxSYM [Abbott Laboratories, Chicago, IL], and TDx [Abbott Laboratories]). Despite reduced dose, we found significantly higher cyclosporine concentrations measured by the EMIT, AxSYM, and TDx assays in various patient groups. These results are due to the increased metabolite/cyclosporine ratio in the late posttransplantation period. In particular, the metabolites AM1 and AM19 increased significantly over time in bone marrow transplant recipients. Therefore, cyclosporine levels measured by immunoassays should be interpreted with caution.  (+info)

Effect of preoperative hyperinflation on static lung volumes after lung transplantation. (7/140)

It is still not known whether persistent increases in functional residual capacity (FRC) and residual volume (RV) after lung transplantation are due to preexisting hyperinflation. Therefore, the aim of this study was to determine the effects of chronic lung hyperinflation on static lung volumes after heart/lung (HLT) and bilateral lung transplantation (BLT). Static lung volumes were measured in 33 patients before and at 6 month intervals for up to 3 yrs after HLT (n=25) or BLT (n=8). The preoperative diagnosis was cystic fibrosis in 25 patients and other chronic hyperinflated lung diseases in eight patients. After surgery, total lung capacity returned to predicted normal values but FRC and RV remained greater than expected for either the recipient or the donor. At 1 yr after surgery, mean+/-SD FRC and RV were 130+/-18% and 151+/-34% of the predicted values for the recipient (p<0.001), and these figures did not change significantly over time. Similar abnormalities were found in patients with and without cystic fibrosis. After transplantation for lung diseases producing chronic hyperinflation, there is a persistent increase in functional residual capacity and residual volume. This alteration is present in patients operated on for diseases developed in both childhood and adulthood and is not recovered over time. It may be due to irreversible changes in the structure of the ribcage.  (+info)

Nocardia infection in heart-lung transplant recipients at Alfred Hospital, Melbourne, Australia, 1989-1998. (8/140)

Nocardia infections are uncommon in recipients of heart, lung, or heart-lung transplants, but such infections are well described. Frequent episodes of rejection, high-dose prednisolone treatment, renal impairment, and prolonged respiratory support have all been shown to increase the risk of Nocardia infection in this group. In this retrospective review of 540 recipients of heart, lung, or heart-lung transplants, 10 patients developed Nocardia infection (frequency, 1.85%). Infection occurred at a mean +/- standard deviation of 13+/-14.5 months after transplantation. All patients had pulmonary disease with no evidence of extrapulmonary disease. The Nocardia infection did not contribute directly to patient deaths. Coinfection with other pathogens was present in 6 patients, and 2 patients had sequential infections. Radiological findings varied. All isolates were susceptible to trimethoprim-sulfamethoxazole, amikacin, and imipenem. Treatment regimens varied. Two (30%) of 6 patients treated with trimethoprim-sulfamethoxazole developed adverse reactions, which necessitated a change in antibiotic therapy. The optimal treatment regimen, which comprises both the antimicrobial agent and the length of treatment, is unclear.  (+info)

Heart-lung transplantation is a surgical procedure where both the heart and lungs of a patient are replaced with those from a deceased donor. This complex and highly specialized surgery is typically considered as a last resort for patients suffering from end-stage lung or heart-lung diseases, such as cystic fibrosis, pulmonary fibrosis, chronic obstructive pulmonary disease (COPD), or certain forms of congenital heart disease, who have exhausted all other treatment options and face imminent death.

The procedure involves removing the patient's diseased heart and lungs en bloc, followed by implanting the donor's heart and lungs in their place. The surgery requires a skilled multidisciplinary team of cardiothoracic surgeons, anesthesiologists, perfusionists, transplant coordinators, and intensive care specialists.

Following the transplantation, patients require lifelong immunosuppressive therapy to prevent rejection of the transplanted organs. Despite the significant risks associated with this procedure, including infection, bleeding, and rejection, heart-lung transplantation can significantly improve both survival and quality of life for carefully selected patients with advanced heart-lung disease.

Lung transplantation is a surgical procedure where one or both diseased lungs are removed and replaced with healthy lungs from a deceased donor. It is typically considered as a treatment option for patients with end-stage lung diseases, such as chronic obstructive pulmonary disease (COPD), cystic fibrosis, idiopathic pulmonary fibrosis, and alpha-1 antitrypsin deficiency, who have exhausted all other medical treatments and continue to suffer from severe respiratory failure.

The procedure involves several steps, including evaluating the patient's eligibility for transplantation, matching the donor's lung size and blood type with the recipient, and performing the surgery under general anesthesia. After the surgery, patients require close monitoring and lifelong immunosuppressive therapy to prevent rejection of the new lungs.

Lung transplantation can significantly improve the quality of life and survival rates for some patients with end-stage lung disease, but it is not without risks, including infection, bleeding, and rejection. Therefore, careful consideration and thorough evaluation are necessary before pursuing this treatment option.

Bronchiolitis obliterans is a medical condition characterized by the inflammation and scarring (fibrosis) of the bronchioles, which are the smallest airways in the lungs. This results in the narrowing or complete obstruction of the airways, leading to difficulty breathing and reduced lung function.

The condition is often caused by a respiratory infection, such as adenovirus or mycoplasma pneumonia, but it can also be associated with exposure to certain chemicals, drugs, or radiation therapy. In some cases, the cause may be unknown.

Symptoms of bronchiolitis obliterans include cough, shortness of breath, wheezing, and crackles heard on lung examination. Diagnosis typically involves a combination of medical history, physical exam, imaging studies (such as chest X-ray or CT scan), and pulmonary function tests. In some cases, a biopsy may be necessary to confirm the diagnosis.

Treatment for bronchiolitis obliterans is focused on managing symptoms and preventing further lung damage. This may include bronchodilators to help open up the airways, corticosteroids to reduce inflammation, and oxygen therapy to help with breathing. In severe cases, a lung transplant may be necessary.

A lung is a pair of spongy, elastic organs in the chest that work together to enable breathing. They are responsible for taking in oxygen and expelling carbon dioxide through the process of respiration. The left lung has two lobes, while the right lung has three lobes. The lungs are protected by the ribcage and are covered by a double-layered membrane called the pleura. The trachea divides into two bronchi, which further divide into smaller bronchioles, leading to millions of tiny air sacs called alveoli, where the exchange of gases occurs.

Liver transplantation is a surgical procedure in which a diseased or failing liver is replaced with a healthy one from a deceased donor or, less commonly, a portion of a liver from a living donor. The goal of the procedure is to restore normal liver function and improve the patient's overall health and quality of life.

Liver transplantation may be recommended for individuals with end-stage liver disease, acute liver failure, certain genetic liver disorders, or liver cancers that cannot be treated effectively with other therapies. The procedure involves complex surgery to remove the diseased liver and implant the new one, followed by a period of recovery and close medical monitoring to ensure proper function and minimize the risk of complications.

The success of liver transplantation has improved significantly in recent years due to advances in surgical techniques, immunosuppressive medications, and post-transplant care. However, it remains a major operation with significant risks and challenges, including the need for lifelong immunosuppression to prevent rejection of the new liver, as well as potential complications such as infection, bleeding, and organ failure.

Homologous transplantation is a type of transplant surgery where organs or tissues are transferred between two genetically non-identical individuals of the same species. The term "homologous" refers to the similarity in structure and function of the donated organ or tissue to the recipient's own organ or tissue.

For example, a heart transplant from one human to another is an example of homologous transplantation because both organs are hearts and perform the same function. Similarly, a liver transplant, kidney transplant, lung transplant, and other types of organ transplants between individuals of the same species are also considered homologous transplantations.

Homologous transplantation is in contrast to heterologous or xenogeneic transplantation, where organs or tissues are transferred from one species to another, such as a pig heart transplanted into a human. Homologous transplantation is more commonly performed than heterologous transplantation due to the increased risk of rejection and other complications associated with xenogeneic transplants.

Primary graft dysfunction (PGD) is a severe complication that can occur after an organ transplant, such as a lung or heart transplant. It refers to the early functional impairment of the grafted organ that is not due to surgical complications, rejection, or recurrence of the original disease.

In the case of lung transplants, PGD is defined as the evidence of poor oxygenation and stiffness in the lungs within the first 72 hours after the transplant. It is typically caused by inflammation, injury to the blood vessels, or other damage to the lung tissue during the transplant procedure or due to pre-existing conditions in the donor organ.

PGD can lead to serious complications, including respiratory failure, and is associated with increased morbidity and mortality after transplantation. Treatment may include supportive care, such as mechanical ventilation and medications to support lung function, as well as strategies to reduce inflammation and prevent further damage to the grafted organ.

In medical terms, the heart is a muscular organ located in the thoracic cavity that functions as a pump to circulate blood throughout the body. It's responsible for delivering oxygen and nutrients to the tissues and removing carbon dioxide and other wastes. The human heart is divided into four chambers: two atria on the top and two ventricles on the bottom. The right side of the heart receives deoxygenated blood from the body and pumps it to the lungs, while the left side receives oxygenated blood from the lungs and pumps it out to the rest of the body. The heart's rhythmic contractions and relaxations are regulated by a complex electrical conduction system.

Graft rejection is an immune response that occurs when transplanted tissue or organ (the graft) is recognized as foreign by the recipient's immune system, leading to the activation of immune cells to attack and destroy the graft. This results in the failure of the transplant and the need for additional medical intervention or another transplant. There are three types of graft rejection: hyperacute, acute, and chronic. Hyperacute rejection occurs immediately or soon after transplantation due to pre-existing antibodies against the graft. Acute rejection typically occurs within weeks to months post-transplant and is characterized by the infiltration of T-cells into the graft. Chronic rejection, which can occur months to years after transplantation, is a slow and progressive process characterized by fibrosis and tissue damage due to ongoing immune responses against the graft.

Heart transplantation is a surgical procedure where a diseased, damaged, or failing heart is removed and replaced with a healthy donor heart. This procedure is usually considered as a last resort for patients with end-stage heart failure or severe coronary artery disease who have not responded to other treatments. The donor heart typically comes from a brain-dead individual whose family has agreed to donate their loved one's organs for transplantation. Heart transplantation is a complex and highly specialized procedure that requires a multidisciplinary team of healthcare professionals, including cardiologists, cardiac surgeons, anesthesiologists, perfusionists, nurses, and other support staff. The success rates for heart transplantation have improved significantly over the past few decades, with many patients experiencing improved quality of life and increased survival rates. However, recipients of heart transplants require lifelong immunosuppressive therapy to prevent rejection of the donor heart, which can increase the risk of infections and other complications.

Kidney transplantation is a surgical procedure where a healthy kidney from a deceased or living donor is implanted into a patient with end-stage renal disease (ESRD) or permanent kidney failure. The new kidney takes over the functions of filtering waste and excess fluids from the blood, producing urine, and maintaining the body's electrolyte balance.

The transplanted kidney is typically placed in the lower abdomen, with its blood vessels connected to the recipient's iliac artery and vein. The ureter of the new kidney is then attached to the recipient's bladder to ensure proper urine flow. Following the surgery, the patient will require lifelong immunosuppressive therapy to prevent rejection of the transplanted organ by their immune system.

Lung diseases refer to a broad category of disorders that affect the lungs and other structures within the respiratory system. These diseases can impair lung function, leading to symptoms such as coughing, shortness of breath, chest pain, and wheezing. They can be categorized into several types based on the underlying cause and nature of the disease process. Some common examples include:

1. Obstructive lung diseases: These are characterized by narrowing or blockage of the airways, making it difficult to breathe out. Examples include chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, and cystic fibrosis.
2. Restrictive lung diseases: These involve stiffening or scarring of the lungs, which reduces their ability to expand and take in air. Examples include idiopathic pulmonary fibrosis, sarcoidosis, and asbestosis.
3. Infectious lung diseases: These are caused by bacteria, viruses, fungi, or parasites that infect the lungs. Examples include pneumonia, tuberculosis, and influenza.
4. Vascular lung diseases: These affect the blood vessels in the lungs, impairing oxygen exchange. Examples include pulmonary embolism, pulmonary hypertension, and chronic thromboembolic pulmonary hypertension (CTEPH).
5. Neoplastic lung diseases: These involve abnormal growth of cells within the lungs, leading to cancer. Examples include small cell lung cancer, non-small cell lung cancer, and mesothelioma.
6. Other lung diseases: These include interstitial lung diseases, pleural effusions, and rare disorders such as pulmonary alveolar proteinosis and lymphangioleiomyomatosis (LAM).

It is important to note that this list is not exhaustive, and there are many other conditions that can affect the lungs. Proper diagnosis and treatment of lung diseases require consultation with a healthcare professional, such as a pulmonologist or respiratory therapist.

Bone marrow transplantation (BMT) is a medical procedure in which damaged or destroyed bone marrow is replaced with healthy bone marrow from a donor. Bone marrow is the spongy tissue inside bones that produces blood cells. The main types of BMT are autologous, allogeneic, and umbilical cord blood transplantation.

In autologous BMT, the patient's own bone marrow is used for the transplant. This type of BMT is often used in patients with lymphoma or multiple myeloma who have undergone high-dose chemotherapy or radiation therapy to destroy their cancerous bone marrow.

In allogeneic BMT, bone marrow from a genetically matched donor is used for the transplant. This type of BMT is often used in patients with leukemia, lymphoma, or other blood disorders who have failed other treatments.

Umbilical cord blood transplantation involves using stem cells from umbilical cord blood as a source of healthy bone marrow. This type of BMT is often used in children and adults who do not have a matched donor for allogeneic BMT.

The process of BMT typically involves several steps, including harvesting the bone marrow or stem cells from the donor, conditioning the patient's body to receive the new bone marrow or stem cells, transplanting the new bone marrow or stem cells into the patient's body, and monitoring the patient for signs of engraftment and complications.

BMT is a complex and potentially risky procedure that requires careful planning, preparation, and follow-up care. However, it can be a life-saving treatment for many patients with blood disorders or cancer.

Hematopoietic Stem Cell Transplantation (HSCT) is a medical procedure where hematopoietic stem cells (immature cells that give rise to all blood cell types) are transplanted into a patient. This procedure is often used to treat various malignant and non-malignant disorders affecting the hematopoietic system, such as leukemias, lymphomas, multiple myeloma, aplastic anemia, inherited immune deficiency diseases, and certain genetic metabolic disorders.

The transplantation can be autologous (using the patient's own stem cells), allogeneic (using stem cells from a genetically matched donor, usually a sibling or unrelated volunteer), or syngeneic (using stem cells from an identical twin).

The process involves collecting hematopoietic stem cells, most commonly from the peripheral blood or bone marrow. The collected cells are then infused into the patient after the recipient's own hematopoietic system has been ablated (or destroyed) using high-dose chemotherapy and/or radiation therapy. This allows the donor's stem cells to engraft, reconstitute, and restore the patient's hematopoietic system.

HSCT is a complex and potentially risky procedure with various complications, including graft-versus-host disease, infections, and organ damage. However, it offers the potential for cure or long-term remission in many patients with otherwise fatal diseases.

Graft survival, in medical terms, refers to the success of a transplanted tissue or organ in continuing to function and integrate with the recipient's body over time. It is the opposite of graft rejection, which occurs when the recipient's immune system recognizes the transplanted tissue as foreign and attacks it, leading to its failure.

Graft survival depends on various factors, including the compatibility between the donor and recipient, the type and location of the graft, the use of immunosuppressive drugs to prevent rejection, and the overall health of the recipient. A successful graft survival implies that the transplanted tissue or organ has been accepted by the recipient's body and is functioning properly, providing the necessary physiological support for the recipient's survival and improved quality of life.

A tissue donor is an individual who has agreed to allow organs and tissues to be removed from their body after death for the purpose of transplantation to restore the health or save the life of another person. The tissues that can be donated include corneas, heart valves, skin, bone, tendons, ligaments, veins, and cartilage. These tissues can enhance the quality of life for many recipients and are often used in reconstructive surgeries. It is important to note that tissue donation does not interfere with an open casket funeral or other cultural or religious practices related to death and grieving.

Autologous transplantation is a medical procedure where cells, tissues, or organs are removed from a person, stored and then returned back to the same individual at a later time. This is different from allogeneic transplantation where the tissue or organ is obtained from another donor. The term "autologous" is derived from the Greek words "auto" meaning self and "logos" meaning study.

In autologous transplantation, the patient's own cells or tissues are used to replace or repair damaged or diseased ones. This reduces the risk of rejection and eliminates the need for immunosuppressive drugs, which are required in allogeneic transplants to prevent the body from attacking the foreign tissue.

Examples of autologous transplantation include:

* Autologous bone marrow or stem cell transplantation, where stem cells are removed from the patient's blood or bone marrow, stored and then reinfused back into the same individual after high-dose chemotherapy or radiation therapy to treat cancer.
* Autologous skin grafting, where a piece of skin is taken from one part of the body and transplanted to another area on the same person.
* Autologous chondrocyte implantation, where cartilage cells are harvested from the patient's own knee, cultured in a laboratory and then implanted back into the knee to repair damaged cartilage.

Heart rate is the number of heartbeats per unit of time, often expressed as beats per minute (bpm). It can vary significantly depending on factors such as age, physical fitness, emotions, and overall health status. A resting heart rate between 60-100 bpm is generally considered normal for adults, but athletes and individuals with high levels of physical fitness may have a resting heart rate below 60 bpm due to their enhanced cardiovascular efficiency. Monitoring heart rate can provide valuable insights into an individual's health status, exercise intensity, and response to various treatments or interventions.

MedlinePlus is not a medical term, but rather a consumer health website that provides high-quality, accurate, and reliable health information, written in easy-to-understand language. It is produced by the U.S. National Library of Medicine, the world's largest medical library, and is widely recognized as a trusted source of health information.

MedlinePlus offers information on various health topics, including conditions, diseases, tests, treatments, and wellness. It also provides access to drug information, medical dictionary, and encyclopedia, as well as links to clinical trials, medical news, and patient organizations. The website is available in both English and Spanish and can be accessed for free.

A pulmonary embolism (PE) is a medical condition that occurs when a blood clot, often formed in the deep veins of the legs (deep vein thrombosis), breaks off and travels to the lungs, blocking one or more pulmonary arteries. This blockage can lead to various symptoms such as shortness of breath, chest pain, rapid heart rate, and coughing up blood. In severe cases, it can cause life-threatening complications like low oxygen levels, hypotension, and even death if not promptly diagnosed and treated with anticoagulant medications or thrombolytic therapy to dissolve the clot.

Angiography is a medical procedure in which an x-ray image is taken to visualize the internal structure of blood vessels, arteries, or veins. This is done by injecting a radiopaque contrast agent (dye) into the blood vessel using a thin, flexible catheter. The dye makes the blood vessels visible on an x-ray image, allowing doctors to diagnose and treat various medical conditions such as blockages, narrowing, or malformations of the blood vessels.

There are several types of angiography, including:

* Cardiac angiography (also called coronary angiography) - used to examine the blood vessels of the heart
* Cerebral angiography - used to examine the blood vessels of the brain
* Peripheral angiography - used to examine the blood vessels in the limbs or other parts of the body.

Angiography is typically performed by a radiologist, cardiologist, or vascular surgeon in a hospital setting. It can help diagnose conditions such as coronary artery disease, aneurysms, and peripheral arterial disease, among others.

Digital subtraction angiography (DSA) is a medical imaging technique used to visualize the blood vessels and blood flow within the body. It combines the use of X-ray technology with digital image processing to produce detailed images of the vascular system.

In DSA, a contrast agent is injected into the patient's bloodstream through a catheter, which is typically inserted into an artery in the leg and guided to the area of interest using fluoroscopy. As the contrast agent flows through the blood vessels, X-ray images are taken at multiple time points.

The digital subtraction process involves taking a baseline image without contrast and then subtracting it from subsequent images taken with contrast. This allows for the removal of background structures and noise, resulting in clearer images of the blood vessels. DSA can be used to diagnose and evaluate various vascular conditions, such as aneurysms, stenosis, and tumors, and can also guide interventional procedures such as angioplasty and stenting.

The Ventilation-Perfusion (V/Q) ratio is a measure used in respiratory physiology to describe the relationship between the amount of air that enters the alveoli (ventilation) and the amount of blood that reaches the alveoli to pick up oxygen (perfusion).

In a healthy lung, these two processes are well-matched, meaning that well-ventilated areas of the lung also have good blood flow. This results in a V/Q ratio close to 1.0.

However, certain lung conditions such as emphysema or pulmonary embolism can cause ventilation and perfusion to become mismatched, leading to a V/Q ratio that is either higher (ventilation exceeds perfusion) or lower (perfusion exceeds ventilation) than normal. This mismatch can result in impaired gas exchange and lead to hypoxemia (low oxygen levels in the blood).

The V/Q ratio is often used in clinical settings to assess lung function and diagnose respiratory disorders.

Technetium Tc 99m Aggregated Albumin is a radiopharmaceutical preparation used in diagnostic imaging. It consists of radioactive technetium-99m (^99m^Tc) chemically bonded to human serum albumin, which has been aggregated to increase its size and alter its clearance from the body.

The resulting compound is injected into the patient's bloodstream, where it accumulates in the reticuloendothelial system (RES), including the liver, spleen, and bone marrow. The radioactive emission of technetium-99m can then be detected by a gamma camera, producing images that reflect the distribution and function of the RES.

This imaging technique is used to diagnose and monitor various conditions, such as liver disease, inflammation, or tumors. It provides valuable information about the patient's health status and helps guide medical decision-making.

The pulmonary artery is a large blood vessel that carries deoxygenated blood from the right ventricle of the heart to the lungs for oxygenation. It divides into two main branches, the right and left pulmonary arteries, which further divide into smaller vessels called arterioles, and then into a vast network of capillaries in the lungs where gas exchange occurs. The thin walls of these capillaries allow oxygen to diffuse into the blood and carbon dioxide to diffuse out, making the blood oxygen-rich before it is pumped back to the left side of the heart through the pulmonary veins. This process is crucial for maintaining proper oxygenation of the body's tissues and organs.

Sodium Pertechnetate Tc 99m is a radioactive pharmaceutical preparation used in medical diagnostic imaging. It is a technetium-99m radiopharmaceutical, where technetium-99m is a metastable nuclear isomer of technetium-99, which emits gamma rays and has a half-life of 6 hours. Sodium Pertechnetate Tc 99m is used as a contrast agent in various diagnostic procedures, such as imaging of the thyroid, salivary glands, or the brain, to evaluate conditions like inflammation, tumors, or abnormalities in blood flow. It is typically administered intravenously, and its short half-life ensures that the radiation exposure is limited.

... is a monthly peer-reviewed medical journal covering heart and lung ... It was established in 1981 as Heart Transplantation, and was renamed to the Journal of Heart Transplantation in 1984. It ... "The Journal of Heart and Lung Transplantation". 2021 Journal Citation Reports. Web of Science (Science ed.). Clarivate ... It is published by Elsevier on behalf of the International Society for Heart and Lung Transplantation, of which is the official ...
"International Society for Heart & Lung Transplantation Reveals 2014 Award Winners". PRWeb. Retrieved 2018-08-08. "ISHLT: The ... "International Society for Heart & Lung Transplantation Reveals 2014 Award Winners". Prweb.com. Retrieved 3 February 2019. Green ... It holds annual scientific meetings and publishes The Journal of Heart and Lung Transplantation. It also holds the worlds ... ISHLT history archives The Journal of Heart and Lung Transplantation (CS1 German-language sources (de), Articles with ISNI ...
... United Network for Organ Sharing International Society for Heart and Lung Transplantation Lung Transplant ... Lung transplantation, or pulmonary transplantation, is a surgical procedure in which one or both lungs are replaced by lungs ... In the case of a singular lung transplant the lung is collapsed, the blood vessels in the lung tied off, and the lung removed ... this type of transplant typically involves the transplantation of a heart and lungs into recipient A, whose own healthy heart ...
LeGal, Yves M. (May 1990). "Lung and heart-lung transplantation". The Annals of Thoracic Surgery. 49 (5): 840-844. Retrieved 27 ...
... the Journal of Heart and Lung Transplantation. He was also president of the Heart Failure Society of America. Mandeep Rajinder ... the Journal of Heart and Lung Transplantation. In 2016, he was appointed president of the Heart Failure Society of America. He ... History of International Heart and Lung Transplantation, co-authored with James K. Kirklin and Lori J. West, Elsevier (2010). ... Journal of Heart and Lung Transplantation. Retrieved June 6, 2015. Stiles, Steve (February 1, 2012). "Dr Mandeep Mehra leaves ...
Lung Transplantation Reveals 2014 Award Winners" (PDF). International Society for Heart & Lung Transplantation. 10 April 2014. ... A Jarvic 7 heart was used as a bridge to transplantation until a human donor heart could be found and the patient subsequently ... 2014 - Lifetime Achievement Award from the International Society for Heart and Lung Transplantation in Recognition of ... Peter Pugh (2015). The Heart of the Matter: How Papworth Hospital transformed modern heart and lung care. Icon Books Limited. ...
"What's old is new again: Palliative Potts shunt in children with PAH". International Society for Heart & Lung Transplantation ... the group of heart defects that result in insufficient blood flow to the lungs. They became intrigued by the idea of somehow ... resulting in too much blood flow to the lungs and congestive heart failure). Some babies with a Potts shunt experienced ... Open heart surgery had become common by this time, and Potts said that it should be performed "by young men whose fingers are ...
Burch M.; Aurora P. (2004). "Current status of paediatric heart, lung, and heart-lung transplantation". Archives of Disease in ... The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: A 10-year update. J ... 2010). "The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients". ... Orthotopic heart transplantation: the bicaval technique Heart Treatments - Heart Treatments , NHLBI, NIH NIH (Articles with ...
doi:10.1161/CIRCULATIONAHA.109.885756 Burch, M., & Aurora, P. (2004). Current status of paediatric heart, lung, and heart-lung ... Intentional ABO-incompatible heart transplantation: a case report of 2 adult patients. The Journal of Heart and Lung ... The Journal of Heart and Lung Transplantation, 28(12), 1254-1260. doi:10.1016/j.healun.2009.06.024 Roche, S. L., Burch, M., ... The Journal of Heart and Lung Transplantation, 32(3), 285-292. doi:10.1016/j.healun.2012.11.022 United Network for Organ ...
Eddy, S. "Dextrocardia and Proper Lead Placement". Deuse, Tobias; Reitz, Bruce A. (September 2009). "Heart-Lung Transplantation ... When heart transplantation is required in a person with situs inversus, reconstruction of the venous pathways to accommodate a ... In this form of dextrocardia, the heart is simply placed further right in the thorax than is normal. It is commonly associated ... Dextrocardia situs inversus refers to the heart being a mirror image situated on the right side. For all visceral organs to be ...
The Journal of Heart and Lung Transplantation. 24 (3): 246-250. doi:10.1016/j.healun.2004.01.015. PMID 15737749. Cui Q, Lim SK ... The cardiac crescent forms two heart fields; primary heart field and the secondary heart field. At this point in development, ... the two heart fields fuse to form a primitive, single-chambered heart referred to as the primary myocardium. The secondary ( ... heart field of these cardiac crescent cells will give rise to the outflow tract and the right ventricle of the mature heart. A ...
... a dilemma for lung transplantation". The Journal of Heart and Lung Transplantation. 22 (2): 210-213. doi:10.1016/S1053-2498(02) ... The Journal of Heart and Lung Transplantation. 26 (3): 296-298. doi:10.1016/j.healun.2006.12.004. PMID 17346635. Delgado JF, ... The Journal of Heart and Lung Transplantation. 25 (9): 1171-1174. doi:10.1016/j.healun.2006.05.013. PMID 16962483. McWilliams ... Lung toxicity is a serious complication associated with sirolimus therapy,[excessive citations] especially in the case of lung ...
The Journal of Heart and Lung Transplantation. 29 (5): 509-516. doi:10.1016/j.healun.2009.11.602. PMID 20061166. Sombogaard F, ... 2008). "Association of four DNA polymorphisms with acute rejection after kidney transplantation". Transpl. Int. 21 (9): 879-91 ... 2010). "Genetic polymorphisms influence mycophenolate mofetil-related adverse events in pediatric heart transplant patients". ... a 2-year follow-up in kidney transplantation". Clin. Pharmacol. Ther. 83 (2): 328-35. doi:10.1038/sj.clpt.6100300. PMID ...
The Journal of Heart and Lung Transplantation. 27 (4): 457-61. doi:10.1016/j.healun.2008.01.013. PMID 18374884. Basic & ... heart arrhythmia - decrease the output of sinus node thus stabilizing heart function coronary artery disease - reduce heart ... Ørn S, Dickstein K (2002-04-01). "How do heart failure patients die?". European Heart Journal Supplements. 4 (Suppl D): D59-D65 ... Circulation & Lung Physiology I Archived 2011-07-26 at the Wayback Machine M.A.S.T.E.R. Learning Program, UC Davis School of ...
"Utility of Virtual Crossmatch in Sensitized Patients Awaiting Heart Transplantation". The Journal of Heart and Lung ... The Journal of Heart and Lung Transplantation. 28 (1): 51-57. doi:10.1016/j.healun.2008.09.012. PMID 19134531. Quentin L. Cook ... The Journal of Heart and Lung Transplantation. 28 (8): 838-842. doi:10.1016/j.healun.2009.04.031. PMC 2758491. PMID 19632582. ... The Journal of Heart and Lung Transplantation. 28 (12): 1254-1260. doi:10.1016/j.healun.2009.06.024. PMID 19782582. Drakos, ...
The Journal of Heart and Lung Transplantation. 21 (10): 1131-4. doi:10.1016/s1053-2498(02)00404-7. PMID 12398880. Arenas R, ... "Delayed sternotomy wound infection due to Paecilomyces variotii in a lung transplant recipient". ...
Cabrol was involved with the International Society for Heart and Lung Transplantation (ISHLT) from its inception in 1981. In ... "ISHLT: The International Society for Heart & Lung Transplantation - Past Presidents". www.ishlt.org. Retrieved 3 January 2019. ... Copeland, Jack (September 2017). "Professor Christian Cabrol (1925 to 2017)". The Journal of Heart and Lung Transplantation. 36 ... West, Lori J. (21 April 2014). "ISHLT: The International Society for Heart & Lung Transplantation - Video Interviews - ...
The Journal of Heart and Lung Transplantation. 34 (11): 1366-1375. doi:10.1016/j.healun.2015.05.025. PMID 26210752. Boucher P, ... and heart failure. Use during pregnancy may result in harm to the baby. Imatinib works by stopping the Bcr-Abl tyrosine-kinase ... Transplantation Proceedings. 41 (5): 1969-1971. doi:10.1016/j.transproceed.2009.02.100. PMID 19545770. Frost AE, Barst RJ, ...
The Journal of Heart and Lung Transplantation. 21 (10): 1074-9. doi:10.1016/S1053-2498(02)00440-0. PMID 12398872. CD69+protein ... "Effect of mycophenolate mofetil therapy on lymphocyte activation in heart transplant recipients". ...
The Journal of Heart and Lung Transplantation. 27 (4): 457-61. doi:10.1016/j.healun.2008.01.013. PMID 18374884. Davis E, ... Heart muscle contraction Increase cardiac output (minor degree compared to β1). Increases heart rate in sinoatrial node (SA ... April 2008). "Clenbuterol increases lean muscle mass but not endurance in patients with chronic heart failure". ...
The Journal of Heart and Lung Transplantation. 38 (4): 475-476. doi:10.1016/j.healun.2019.01.001. PMID 30661974. S2CID 58613504 ...
The Journal of Heart and Lung Transplantation. 34 (12): 1515-1526. doi:10.1016/j.healun.2015.10.024. PMID 26681121. Retrieved 1 ... J Heart Lung Transplant. 29 (6): 616-24. doi:10.1016/j.healun.2010.02.003. PMID 20400335. Slater JP, Rose EA, Levin HR, et al. ... J Heart Lung Transplant. 33 (1): 51-9. doi:10.1016/j.healun.2013.10.005. PMID 24290832. Slaughter, MS; Naka, Y; John, R; et al ... J Heart Lung Transpl. 33 (4): S11. doi:10.1016/j.healun.2014.01.055. Kirklin, JK; Naftel, DC; Kormos, RL; et al. (2014). " ...
"Outcomes of lung transplantation for primary ciliary dyskinesia and Kartagener syndrome". The Journal of Heart and Lung ... "Prognostic Factors Influencing Survival Rates in Children Following Lung Transplantation". Transplantation Proceedings. 40 (9 ... with lung transplantation required in severe cases. Susceptibility to infections can be drastically reduced by an early ... with some people progressing to lung transplant. Decline in lung function in people with PCD has been observed in most studies ...
"The Journal of Heart and Lung Transplantation: 50 years of heart transplantation progress". EurekAlert!. 4 December 2017. ... founder and first president of the International Society for Heart and Lung Transplantation". The Journal of Heart and Lung ... ISBN 978-94-010-6805-5. "A Quarter Century of Achievements in Heart and Lung Transplantation". www.medscape.com. Retrieved 16 ... ISHLT monograph series, Volume 4: The history of international heart and lung transplantation. Elsevier Publishers, ...
... and three-year experience in heart transplantation". The Journal of Heart and Lung Transplantation. 13 (4): 571-82. PMID ... They subsequently demonstrated that it was useful in organ transplantation in experimental rats. After successful clinical ... Clinical Transplantation. 10 (1 Pt 2): 77-84. PMID 8680053. Allison, AC; Eugui, EM (1993). "The design and development of an ... as well as for immune rejection in organ transplantation. He developed an idea that if a molecule that could block the enzyme ...
The Journal of Heart and Lung Transplantation. 21 (12): 1290-5. doi:10.1016/s1053-2498(02)00459-x. PMID 12490274. Sinha R, ... and recurring heart attacks for patients with reduced heart function following a heart attack. Carvedilol has also been proven ... Carvedilol, sold under the brand name Coreg among others, is a medication used to treat high blood pressure, congestive heart ... There is no reflex tachycardia response due to carvedilol blockade of β1-adrenergic receptors on the heart. Carvedilol is about ...
The Journal of Heart and Lung Transplantation. 29 (5): 509-516. doi:10.1016/j.healun.2009.11.602. PMID 20061166. Grover S, ... 2010). "Genetic polymorphisms influence mycophenolate mofetil-related adverse events in pediatric heart transplant patients". ... a 2-year follow-up in kidney transplantation". Clin. Pharmacol. Ther. 83 (2): 328-35. doi:10.1038/sj.clpt.6100300. PMID ...
The Journal of Heart and Lung Transplantation. 36 (12): 1309-1310. doi:10.1016/j.healun.2017.10.006. PMID 29173393. Alistair ... That on 3 December 1967, Naki removed the heart of the deceased Denise Darvall, who was white, for transplantation into Louis ... Despite the retractions, the claim that Naki participated in the 1967 heart transplantation has been perpetuated in journal ... Hidden heart: the true story of the first heart transplant: Christian Barnard and Hamilton Naki. Archived 17 May 2014 at the ...
The Journal of Heart and Lung Transplantation. 33 (3): 298-308. doi:10.1016/j.healun.2013.10.030. PMID 24365767. Petersen TH, ... By seeding the matrix with fetal rat lung cells, a functioning lung was produced. The in vitro-produced lung was successfully ... April 2006). "Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts". Nature Medicine ... Scientists have been able to regenerate whole lungs in vitro from rat lungs using perfusion-decellularization. ...
... and three-year experience in heart transplantation". The Journal of Heart and Lung Transplantation. 13 (4): 571-82. PMID ... Specifically it is used following kidney, heart, and liver transplantation. It can be given by mouth or by injection into a ... Mycophenolate sodium has also been used for the prevention of rejection in liver, heart, or lung transplants in children older ... heart, and liver transplantations, and is marketed under the brands CellCept (mycophenolate mofetil by Roche) and Myfortic ( ...
The Journal of Heart and Lung Transplantation is a monthly peer-reviewed medical journal covering heart and lung ... It was established in 1981 as Heart Transplantation, and was renamed to the Journal of Heart Transplantation in 1984. It ... "The Journal of Heart and Lung Transplantation". 2021 Journal Citation Reports. Web of Science (Science ed.). Clarivate ... It is published by Elsevier on behalf of the International Society for Heart and Lung Transplantation, of which is the official ...
Mark Development and prevention of ischemic contracture ("stone heart") in the pig heart Li, Mei LU ; Qin, Zhi ; Steen, Erik ; ... Mark A machine learning model for prediction of 30-day primary graft failure after heart transplantation Linse, Björn LU ; ... Mark Enhanced survival prediction using explainable artificial intelligence in heart transplantation Lisboa, Paulo J.G. ; ... Myocardial injury biomarkers at point of care for early identification of primary graft dysfunction after heart transplantation ...
For more information, please see the projects "Heart Transplantation" and "Lung Transplantation" ... Heart and Lung transplantations profile in Lund University Research portal Description. ...
BACKGROUND: Lung function is altered by infection and rejection in patients who undergo heart-lung transplantation. The ... METHODS: Thirty three patients who underwent heart-lung transplantation were followed for a mean period of 16.3 months. On 123 ... Role of pulmonary function in the detection of allograft dysfunction after heart-lung transplantation. ... Role of pulmonary function in the detection of allograft dysfunction after heart-lung transplantation. ...
Role of pulmonary function in the detection of allograft dysfunction after heart-lung transplantation. ... Role of pulmonary function in the detection of allograft dysfunction after heart-lung transplantation. ...
Heart and Lung Transplantation. A Society that Includes Basic Science, the Failing Heart and Advanced Lung Disease. ...
Heart and Lung Transplantation. A Society that Includes Basic Science, the Failing Heart and Advanced Lung Disease. ...
Heart and Lung Transplantation. A Society that Includes Basic Science, the Failing Heart and Advanced Lung Disease. ... The Journal of Heart and Lung Transplantation *Call for Applications: JHLT Editor-in-Chief ...
Heart and Lung Transplantation. A Society that Includes Basic Science, the Failing Heart and Advanced Lung Disease. ... The Journal of Heart and Lung Transplantation *Call for Applications: JHLT Editor-in-Chief ...
Heart-Lung Transplantation * Humans * Lung Transplantation* / methods * Lung Transplantation* / mortality * Patient Selection ... 1 Program for Advanced Lung Disease and Lung Transplantation, Pulmonary and Critical Care Division, Department of Medicine, ... Lung transplantation for cystic fibrosis: special considerations Chest. 1996 Mar;109(3):787-98. doi: 10.1378/chest.109.3.787. ...
Lung and Heart-Lung Transplantation - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical ... read more and Heart Transplantation Heart Transplantation Heart transplantation is the removal of a healthy heart from a ... Heart-lung transplantation is the surgical removal of both the heart and lungs from a recently deceased person and then their ... One or both lungs can be transplanted. When a lung disorder has also damaged the heart, one or both lungs and a heart may be ...
CPT 33933 describes the standard backbench preparation of a cadaver donor heart/lung allograft before transplantation, ... Below is a list summarizing the CPT codes for heart/lung transplantation procedures. ... CPT 33944 describes the standard backbench preparation of a cadaver donor heart allograft before transplantation, including the ... CPT 33927 describes the implantation of a total replacement heart system (artificial heart) with recipient cardiectomy. ...
The Registration fee can be paid on site in cash or directly at the BEKB Bank office in Wengen. Unfortunately, credit card payments on site will no longer be available. ...
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title = "Kidney transplantation in previous heart or lung recipients",. abstract = "Outcomes after heart and lung transplants ... keywords = "Heart transplantation, Lung transplantation, Renal transplantation",. author = "Bonnie Lonze and Warren, {D. S.} ... Kidney transplantation in previous heart or lung recipients. In: American Journal of Transplantation. 2009 ; Vol. 9, No. 3. pp ... Kidney transplantation in previous heart or lung recipients. American Journal of Transplantation. 2009 Mar;9(3):578-585. doi: ...
Comparative exploration of psychopathology in heart, liver and lung transplantation. Posted on August 25, 2018. August 23, 2022 ... From the total sample, 37% of liver recipients and 20% of lung had cognitive disorders compared to only 9% of heart recipients ... heart n=22, lung n=5) and 21 from the Transplant Unit of Aristotelian University of Thessaloniki, Hippokratio G.P. Hospital ( ... kidney transplantation (5) Liver transplantation (4) magnetic resonance imaging (5) malignancy (4) matrix metalloproteinases (5 ...
Discover what to expect before, after, and during a lung transplant. ... A lung transplant removes a diseased lung and replaces it with a healthy one. ... The primary NIH organization for research on Lung Transplantation is the National Heart, Lung, and Blood Institute ... National Heart, Lung, and Blood Institute * Organ Procurement and Transplantation Network (Health Resources and Services ...
In 1988, a surgeon sewed a new heart into a cowboy. Nearly 31 years ... Heart and Lung Transplantation. ... Christmas miracles - Chicago surgeon performs 3 kids heart ... Heart and Lung Transplantation. ... Heart in a Box May Create More Options for Transplant Patients *Read more about Heart in a Box May Create More Options for ... Doctors reanimate heart for first-of-its-kind transplant in US *Read more about Doctors reanimate heart for first-of-its- ...
First successful heart-lung transplantation for cystic fibrosis in Israel. In: Transplantation Proceedings. 1999 ; Vol. 31, No ... First successful heart-lung transplantation for cystic fibrosis in Israel. Transplantation Proceedings. 1999 Jun;31(4):1875- ... First successful heart-lung transplantation for cystic fibrosis in Israel. Transplantation Proceedings, 31(4), 1875-1877. https ... First successful heart-lung transplantation for cystic fibrosis in Israel, Transplantation Proceedings, vol. 31, no. 4, pp. ...
American Society of Transplantation. *American Society of Transplant Surgeons. *International Society for Heart and Lung ...
... indications for lung transplantation (seen in explanted lungs), surgical complications (airway anastomotic and vascular ... Lung transplantation-related pathology encompasses a spectrum of disorders that include, but are not limited to, ... The Registry of the International Society for Heart and Lung Transplantation: twenty-seventh official adult lung and heart-lung ... Thirty-fifth adult lung and heart-lung transplant report-2018; Focus theme: Multiorgan transplantation. J Heart Lung Transplant ...
... controlled trial is required to validate the utility and safety of surveillance bronchoscopy in lung transplantation. ... surveillance bronchoscopy may pose a risk to stable lung transplant recipients. A multi-center, ... Single-institution study evaluating the utility of surveillance bronchoscopy after lung transplantation J Heart Lung Transplant ... BOS and AR were diagnosed according to published guidelines from the International Society for Heart and Lung Transplantation. ...
... and heart-lung transplantation. [119] ... Lung Scintigraphy. Lung scintigraphy may serve for screening or ... The size of the heart is normal. Emphysema is evident at the middle and upper parts of the left lung and, to a lesser extent, ... The size of the heart is normal. Emphysema is evident at the middle and upper parts of the left lung and, to a lesser extent, ... Ventilation-perfusion lung scanning and spiral computed tomography of the lungs: competing or complementary modalities?. Eur J ...
Prospective assessment of pre-existing and de novo anti-HLA IgE in kidney, liver, lung and heart transplantation. ... heart and lung (n=15 each) transplant recipients before and within one-year after transplantation, employing a single-antigen ... These data demonstrate that anti-HLA IgE antibodies occur at low frequency in kidney, liver, heart and lung transplant ... heart, liver and lung cohort). Anti-HLA IgE occurred only in patients that were positive for anti-HLA IgG, and most IgE ...
ECMO Use in Heart and Lung Transplantation *Matthew Bacchetta, Vanderbilt University Medical Center ...
IL for The International Society for Heart and Lung Transplantation as a Member Services Administrator ... Looking to make a difference?The International Society for Heart and Lung Transplantation is seeking a Member Services ... organization dedicated to improving the care of patients with advanced heart or lung disease through transplantation, ...
A prospective multicenter cohort of LTRs was identified in the four lung transplant centers. Paired fecal and serum specimens ... in the setting of lung transplant recipients (LTRs) remains unexplored. ... Thirty-sixth adult lung and heart-lung transplantation Report-2019; focus theme: donor and recipient size match. J. Heart Lung ... The lung microbiome in lung transplantation. J. Heart Lung Transplant. 40, 733-744 (2021). ...
The lung microbiome in lung transplantation. J Heart Lung Transplant. 2021;40:733-44. DOIPubMedGoogle Scholar ... Bacteremic Inquilinus limosus empyema in an Australian lung transplant patient with cystic fibrosis. J Heart Lung Transplant. ... limosus before lung transplantation. Indeed, the lung graft microbiome is affected by donor and recipient factors (6), but ... Of interest, she was colonized before the lung transplantation, but I. limosus has not been isolated since then. ...

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