A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
The hollow, muscular organ that maintains the circulation of the blood.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
Heart failure caused by abnormal myocardial contraction during SYSTOLE leading to defective cardiac emptying.
Heart failure caused by abnormal myocardial relaxation during DIASTOLE leading to defective cardiac filling.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Pathological conditions involving the HEART including its structural and functional abnormalities.
The transference of a heart from one human or animal to another.
A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
Contractile activity of the MYOCARDIUM.
Elements of limited time intervals, contributing to particular results or situations.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Examinations used to diagnose and treat heart conditions.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).
Agents that promote the excretion of urine through their effects on kidney function.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
The chambers of the heart, to which the BLOOD returns from the circulation.
Small pumps, often implantable, designed for temporarily assisting the heart, usually the LEFT VENTRICLE, to pump blood. They consist of a pumping chamber and a power source, which may be partially or totally external to the body and activated by electromagnetic motors.
The confinement of a patient in a hospital.
The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.
AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
Period of contraction of the HEART, especially of the HEART VENTRICLES.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.
A condition in which HEART VENTRICLES exhibit impaired function.
Benzo-indoles similar to CARBOLINES which are pyrido-indoles. In plants, carbazoles are derived from indole and form some of the INDOLE ALKALOIDS.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
Subsequent admissions of a patient to a hospital or other health care institution for treatment.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
The pressure within a CARDIAC VENTRICLE. Ventricular pressure waveforms can be measured in the beating heart by catheterization or estimated using imaging techniques (e.g., DOPPLER ECHOCARDIOGRAPHY). The information is useful in evaluating the function of the MYOCARDIUM; CARDIAC VALVES; and PERICARDIUM, particularly with simultaneous measurement of other (e.g., aortic or atrial) pressures.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
The blood pressure as recorded after wedging a CATHETER in a small PULMONARY ARTERY; believed to reflect the PRESSURE in the pulmonary CAPILLARIES.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Drugs that bind to and block the activation of MINERALOCORTICOID RECEPTORS by MINERALOCORTICOIDS such as ALDOSTERONE.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
A condition of substandard growth or diminished capacity to maintain normal function.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
The restoration of the sequential order of contraction and relaxation of the HEART ATRIA and HEART VENTRICLES by atrio-biventricular pacing.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Disease having a short and relatively severe course.
Drugs used to cause dilation of the blood vessels.
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
Condition where a primary dysfunction of either heart or kidney results in failure of the other organ (e.g., HEART FAILURE with worsening RENAL INSUFFICIENCY).
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Calcium-transporting ATPases that catalyze the active transport of CALCIUM into the SARCOPLASMIC RETICULUM vesicles from the CYTOPLASM. They are primarily found in MUSCLE CELLS and play a role in the relaxation of MUSCLES.
Difficult or labored breathing.
Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Endogenous or exogenous chemicals that regulate the WATER-ELECTROLYTE BALANCE in the body. They consist of peptides and non-peptide compounds.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)
An abnormal pattern of breathing characterized by alternating periods of apnea and deep, rapid breathing. The cycle begins with slow, shallow breaths that gradually increase in depth and rate and is then followed by a period of apnea. The period of apnea can last 5 to 30 seconds, then the cycle repeats every 45 seconds to 3 minutes.
Peptides that regulate the WATER-ELECTROLYTE BALANCE in the body, also known as natriuretic peptide hormones. Several have been sequenced (ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; C-TYPE NATRIURETIC PEPTIDE).
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.
A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
The study of the heart, its physiology, and its functions.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.
Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
The relationship between the dose of an administered drug and the response of the organism to the drug.
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
Drugs that selectively bind to and activate beta-adrenergic receptors.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
An angiotensin-converting enzyme inhibitor that is used to treat HYPERTENSION and HEART FAILURE.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
Failure of equipment to perform to standard. The failure may be due to defects or improper use.
A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
A direct-acting vasodilator that is used as an antihypertensive agent.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)
Agents that antagonize ANGIOTENSIN RECEPTORS. Many drugs in this class specifically target the ANGIOTENSIN TYPE 1 RECEPTOR.
The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.
A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.
The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.
A condition associated with multiple episodes of sleep apnea which are distinguished from obstructive sleep apnea (SLEEP APNEA, OBSTRUCTIVE) by the complete cessation of efforts to breathe. This disorder is associated with dysfunction of central nervous system centers that regulate respiration.
Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.
A type of impedance plethysmography in which bioelectrical impedance is measured between electrodes positioned around the neck and around the lower thorax. It is used principally to calculate stroke volume and cardiac volume, but it is also related to myocardial contractility, thoracic fluid content, and circulation to the extremities.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
A BLOOD PRESSURE regulating system of interacting components that include RENIN; ANGIOTENSINOGEN; ANGIOTENSIN CONVERTING ENZYME; ANGIOTENSIN I; ANGIOTENSIN II; and angiotensinase. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming ANGIOTENSIN I. Angiotensin-converting enzyme, contained in the lung, acts on angiotensin I in the plasma converting it to ANGIOTENSIN II, an extremely powerful vasoconstrictor. Angiotensin II causes contraction of the arteriolar and renal VASCULAR SMOOTH MUSCLE, leading to retention of salt and water in the KIDNEY and increased arterial blood pressure. In addition, angiotensin II stimulates the release of ALDOSTERONE from the ADRENAL CORTEX, which in turn also increases salt and water retention in the kidney. Angiotensin-converting enzyme also breaks down BRADYKININ, a powerful vasodilator and component of the KALLIKREIN-KININ SYSTEM.
A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.
A voluntary organization concerned with the prevention and treatment of heart and vascular diseases.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
A response by the BARORECEPTORS to increased BLOOD PRESSURE. Increased pressure stretches BLOOD VESSELS which activates the baroreceptors in the vessel walls. The net response of the CENTRAL NERVOUS SYSTEM is a reduction of central sympathetic outflow. This reduces blood pressure both by decreasing peripheral VASCULAR RESISTANCE and by lowering CARDIAC OUTPUT. Because the baroreceptors are tonically active, the baroreflex can compensate rapidly for both increases and decreases in blood pressure.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
A phenoxypropanolamine derivative that is a selective beta-1-adrenergic agonist.
This structure includes the thin muscular atrial septum between the two HEART ATRIA, and the thick muscular ventricular septum between the two HEART VENTRICLES.
Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.
Therapy with two or more separate preparations given for a combined effect.
Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
The hemodynamic and electrophysiological action of the right HEART VENTRICLE.
A network of tubules and sacs in the cytoplasm of SKELETAL MUSCLE FIBERS that assist with muscle contraction and relaxation by releasing and storing calcium ions.
Treatment process involving the injection of fluid into an organ or tissue.
A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
General or unspecified injuries to the heart.
A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems.
Surgery performed on the heart.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.
The flow of BLOOD through or around an organ or region of the body.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
Inbred rats derived from Sprague-Dawley rats and used for the study of salt-dependent hypertension. Salt-sensitive and salt-resistant strains have been selectively bred to show the opposite genetically determined blood pressure responses to excess sodium chloride ingestion.

Myocardial osteopontin expression coincides with the development of heart failure. (1/12919)

To identify genes that are differentially expressed during the transition from compensated hypertrophy to failure, myocardial mRNA from spontaneously hypertensive rats (SHR) with heart failure (SHR-F) was compared with that from age-matched SHR with compensated hypertrophy (SHR-NF) and normotensive Wistar-Kyoto rats (WKY) by differential display reverse transcriptase-polymerase chain reaction. Characterization of a transcript differentially expressed in SHR-F yielded a cDNA with homology to the extracellular matrix protein osteopontin. Northern analysis showed low levels of osteopontin mRNA in left ventricular myocardium from WKY and SHR-NF but a markedly increased (approximately 10-fold) level in SHR-F. In myocardium from WKY and SHR-NF, in situ hybridization showed only scant osteopontin mRNA, primarily in arteriolar cells. In SHR-F, in situ hybridization revealed abundant expression of osteopontin mRNA, primarily in nonmyocytes in the interstitial and perivascular space. Similar findings for osteopontin protein were observed in the midwall region of myocardium from the SHR-F group. Consistent with the findings in SHR, osteopontin mRNA was minimally increased (approximately 1.9-fold) in left ventricular myocardium from nonfailing aortic-banded rats with pressure-overload hypertrophy but was markedly increased (approximately 8-fold) in banded rats with failure. Treatment with captopril starting before or after the onset of failure in the SHR reduced the increase in left ventricular osteopontin mRNA levels. Thus, osteopontin expression is markedly increased in the heart coincident with the development of heart failure. The source of osteopontin in SHR-F is primarily nonmyocytes, and its induction is inhibited by an angiotensin-converting enzyme inhibitor, suggesting a role for angiotensin II. Given the known biological activities of osteopontin, including cell adhesion and regulation of inducible nitric oxide synthase gene expression, these data suggest that it could play a role in the pathophysiology of heart failure.  (+info)

Effects of amlodipine on sympathetic nerve traffic and baroreflex control of circulation in heart failure. (2/12919)

Short-acting calcium antagonists exert a sympathoexcitation that in heart failure further enhances an already elevated sympathetic activity. Whether this is also the case for long-acting formulations is not yet established, despite the prognostic importance of sympathetic activation in heart failure. It is also undetermined whether in this condition long-acting calcium antagonists favorably affect a mechanism potentially responsible for the sympathetic activation, ie, the baroreflex impairment. In 28 heart failure patients (NYHA functional class II) under conventional treatment we measured plasma norepinephrine and efferent postganglionic muscle sympathetic nerve activity (microneurography) at rest and during arterial baroreceptor stimulation and deactivation induced by stepwise intravenous infusions of phenylephrine and nitroprusside, respectively. Measurements were performed at baseline and after 8 weeks of daily oral amlodipine administration (10 mg/d, 14 patients) or before and after an 8-week period without calcium antagonist administration (14 patients). Amlodipine caused a small and insignificant blood pressure reduction. Heart rate, left ventricular ejection fraction, and plasma renin and aldosterone concentrations were not affected. This was the case also for plasma norepinephrine (from 2.43+/-0.41 to 2.50+/-0.34 nmol/L, mean+/-SEM), muscle sympathetic nerve activity (from 54.4+/-5.9 to 51.0+/-4.3 bursts/min), and arterial baroreflex responses. No change in the above-mentioned variables was seen in the control group. Thus, in mild heart failure amlodipine treatment does not adversely affect sympathetic activity and baroreflex control of the heart and sympathetic tone. This implies that in this condition long-acting calcium antagonists can be administered without untoward neurohumoral effects anytime conventional treatment needs to be complemented by drugs causing additional vasodilatation.  (+info)

Gender-related differences in myocyte remodeling in progression to heart failure. (3/12919)

Gender-related differences responsible for the better prognosis of females with heart failure have not been clearly established. To address this issue, we investigated potential gender-related differences in myocyte remodeling in spontaneously hypertensive heart failure rats. Echocardiograms and myocyte growth were compared between males and females at compensated (2, 4, and 6 months) and decompensated (18 months in males and 24 months in females) stages of cardiac hypertrophy. Although left ventricular diastolic dimensions did not differ significantly between failing male and female rats, fractional shortening declined significantly only in failing males. Myocyte cross-sectional area did not change after 4 months of age in both genders, which is likely to be responsible for the absence of a change in left ventricular wall thickness during the progression to heart failure. Myocyte volume and cross-sectional area were significantly larger in males than females at 2, 4, and 6 months of age, although there were no significant differences at the failing stage. Reduced adaptive hypertrophic reserve was observed in males, which is likely to contribute to the higher morbidity and mortality of males with chronic heart failure.  (+info)

Hereditary juvenile haemochromatosis: a genetically heterogeneous life-threatening iron-storage disease. (4/12919)

Juvenile haemochromatosis is a rare inborn error of iron metabolism with clinical manifestations before 30 years of age. Unlike adult haemochromatosis which principally affects men, juvenile haemochromatosis affects the sexes equally; it causes early endocrine failure, dilated cardiomyopathy and joint disease. We report four patients (two of each sex) from three pedigrees affected by juvenile haemochromatosis with a mean onset at 22 years (range 14-30). All had endocrine deficiency with postpubertal gonadal failure secondary to pituitary disease; two suffered near-fatal cardiomyopathy with heart failure. Mean time to diagnosis from the first clinical signs of disease was 9.8 years (range 0.5-20) but general health and parameters of iron storage responded favourably to iron-depletion therapy. A 24-year-old man listed for heart transplantation because of cardiomyopathy [left ventricular (LV) ejection fraction 16%] responded to intravenous iron chelation with desferrioxamine combined with phlebotomy (ejection fraction 31%). A 27-year-old woman with subacute biventricular heart failure refractory to medication required orthotopic cardiac transplantation before the diagnosis was established (LV ejection fraction 25%). Genetic studies showed that these two patients with cardiomyopathy from unrelated families were heterozygous for the HFE 845G-->A (C282Y) mutation and wild-type at the H63D locus: complete sequencing of the intron-exon boundaries and entire coding sequence of the HFE gene failed to identify additional lesions. Two siblings in a pedigree without cardiomyopathy were wild-type at the HFE C282Y locus; although the brother harboured a single copy of the 187C-->G (H63D) allele, segregation analysis showed that in neither sibling was the iron-storage disease linked to MHC Class I markers on chromosome 6p. Juvenile haemochromatosis is thus a genetically heterogenous disorder distinct from the common adult variant.  (+info)

Sympathetic nerve alterations assessed with 123I-MIBG in the failing human heart. (5/12919)

Norepinephrine (NE) reuptake function is impaired in heart failure and this may participate in myocyte hyperstimulation by the neurotransmitter. This alteration can be assessed by 123I-metaiodobenzylguanidine (MIBG) scintigraphy. METHODS: To determine whether the impairment of neuronal NE reuptake was reversible after metoprolol therapy, we studied 18 patients (43+/-7 y) with idiopathic dilated cardiomyopathy who were stabilized at least for 3 mo with captopril and diuretics. Patients underwent, before and after 6 mo of therapy with metoprolol, measurements of radionuclide left ventricular ejection fraction (LVEF), maximal oxygen consumption and plasma NE concentration. The cardiac adrenergic innervation function was scintigraphically assessed with MIBG uptake and release measurements on the planar images obtained 20 min and 4 h after tracer injection. To evaluate whether metoprolol had a direct interaction with cardiac MIBG uptake and release, six normal subjects were studied before and after a 1-mo metoprolol intake. RESULTS: In controls, neither cardiac MIBG uptake and release nor circulating NE concentration changed after the 1-mo metoprolol intake. Conversely, after a 6-mo therapy with metoprolol, patients showed increased cardiac MIBG uptake (129%+/-10% versus 138%+/-17%; P = 0.009), unchanged cardiac MIBG release and decreased plasma NE concentration (0.930+/-412 versus 0.721+/-0.370 ng/mL; P = 0.02). In parallel, patients showed improved New York Heart Association class (2.44+/-0.51 versus 2.05+/-0.23; P = 0.004) and increased LVEF (20%+/-8% versus 27%+/-8%; P = 0.0005), whereas maximal oxygen uptake remained unchanged. CONCLUSION: Thus, a parallel improvement of myocardial NE reuptake and of hemodynamics was observed after a 6-mo metoprolol therapy, suggesting that such agents may be beneficial in heart failure by directly protecting the myocardium against excessive NE stimulation.  (+info)

Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus. (6/12919)

OBJECTIVE: To determine rates of morbidity due to cardiovascular and cerebrovascular diseases among women with systemic lupus erythematosus (SLE). METHODS: I used the California Hospital Discharge Database, which contains information on all discharges from acute care hospitals in California, to identify women with SLE who had been hospitalized for treatment of either acute myocardial infarction (AMI), congestive heart failure (CHF), or cerebrovascular accident (CVA) from 1991 to 1994. I compared the proportions of hospitalizations for each cause among women with SLE with those in a group of women without SLE, for 3 age strata (18-44 years, 45-64 years, and > or =65 years). RESULTS: Compared with young women without SLE, young women with SLE were 2.27 times more likely to be hospitalized because of AMI (95% confidence interval [95% CI] 1.08-3.46), 3.80 times more likely to be hospitalized because of CHF (95% CI 2.41-5.19), and 2.05 times more likely to be hospitalized because of CVA (95% CI 1.17-2.93). Among middle-aged women with SLE, the frequencies of hospitalization for AMI and CVA did not differ from those of the comparison group, but the risk of hospitalization for CHF was higher (odds ratio [OR] 1.39, 95% CI 1.05-1.73). Among elderly women with SLE, the risk of hospitalization for AMI was significantly lower (OR 0.70, 95% CI 0.51-0.89), the risk of hospitalization for CHF was higher (OR 1.25, 95% CI 1.01-1.49), and the risk of hospitalization for CVA was not significantly different from those in the comparison group. CONCLUSION: Young women with SLE are at substantially increased risk of AMI, CHF, and CVA. The relative odds of these conditions decrease with age among women with SLE.  (+info)

QT dispersion in patients with chronic heart failure: beta blockers are associated with a reduction in QT dispersion. (7/12919)

OBJECTIVE: To compare QT dispersion in patients with impaired left ventricular systolic function and in matched control patients with normal left ventricular systolic function. DESIGN: A retrospective, case-control study with controls matched 4:1 for age, sex, previous myocardial infarction, and diuretic and beta blocker treatment. SETTING: A regional cardiology centre and a university teaching hospital. PATIENTS: 25 patients with impaired left ventricular systolic function and 100 patients with normal left ventricular systolic function. MAIN OUTCOME MEASURES: QT and QTc dispersion measured by three methods: the difference between maximum and minimum QT and QTc intervals, the standard deviation of QT and QTc intervals, and the "lead adjusted" QT and QTc dispersion. RESULTS: All measures of QT/QTc dispersion were closely interrelated (r values 0.86 to 0.99; all p < 0.001). All measures of QT and QTc dispersion were significantly increased in the patients with impaired left ventricular systolic function v controls (p < 0.001): 71.9 (6.5) (mean (SEM)) v 46.9 (1.7) ms for QT dispersion, and 83.6 (7.6) v 54.3 (2.1) ms(-1-2) for QTc dispersion. All six dispersion parameters were reduced in patients taking beta blockers (p < 0.05), regardless of whether left ventricular function was normal or impaired-by 9.4 (4.6) ms for QT dispersion (p < 0.05) and by 13.8 (6. 5) ms(-1-2) for QTc dispersion (p = 0.01). CONCLUSIONS: QT and QTc dispersion are increased in patients with systolic heart failure in comparison with matched controls, regardless of the method of measurement and independently of possible confounding factors. beta Blockers are associated with a reduction in both QT and QTc dispersion, raising the possibility that a reduction in dispersion of ventricular repolarisation may be an important antiarrhythmic mechanism of beta blockade.  (+info)

Expression of skeletal muscle sarcoplasmic reticulum calcium-ATPase is reduced in rats with postinfarction heart failure. (8/12919)

OBJECTIVE: To determine whether heart failure in rats is associated with altered expression of the skeletal muscle sarcoplasmic reticulum Ca2+-ATPase (SERCA). METHODS: SERCA protein and mRNA were examined in the soleus muscles of eight female rats with heart failure induced by coronary artery ligation, six weeks after the procedure (mean (SEM) left ventricular end diastolic pressure 20.4 (2.2) mm Hg) and in six sham operated controls by western and northern analyses, respectively. RESULTS: SERCA-2a isoform protein was reduced by 16% (112 000 (4000) v 134 000 (2000) arbitrary units, p < 0.001), and SERCA-2a messenger RNA was reduced by 59% (0.24 (0. 06) v 0.58 (0.02) arbitrary units, p < 0.001). Although rats with heart failure had smaller muscles (0.54 mg/g v 0.66 mg/g body weight), no difference in locomotor activity was observed. CONCLUSIONS: These results may explain the previously documented abnormalities in calcium handling in skeletal muscle from animals with the same model of congestive heart failure, and could be responsible for the accelerated muscle fatigue characteristic of patients with heart failure.  (+info)

TY - JOUR. T1 - Acute kidney injury in pediatric acute decompensated heart failure. AU - Medar, Shivanand S.. AU - Hsu, Daphne T.. AU - Lamour, Jacqueline M.. AU - Aydin, Scott I.. PY - 2015/7/22. Y1 - 2015/7/22. N2 - Objective: Acute kidney injury in adult patients with acute decompensated heart failure is associated with increased mortality. There is limited literature in pediatric patients with acute decompensated heart failure and acute kidney injury. We aim to study acute kidney injury in the pediatric acute decompensated heart failure population and its association with specific outcomes. Design: Retrospective, case-control study. Setting: Cardiac ICU in a childrens tertiary care hospital. Patients: Index admissions of patients younger than 21 years with acute decompensated heart failure between January 2008 and December 2012. Interventions: None. Measurements and Main Results: Index admissions of patients younger than 21 years with acute decompensated heart failure between January 2008 ...
http://www.grandviewresearch.com/industry-analysis/congestive-heart-failure-treatment-devices-market. Cardiac assist devices (CAD) held one of the largest shares in congestive heart failure treatment devices market due to the shortage of heart donors and technologically advanced cardiac assist devices in 2013. Additionally, reimbursement coverage for cardiac device implantation procedures is anticipated to provide this segment with growth platform.. North America dominated the overall market in terms of revenue owing to the increasing incidence rates of high blood pressure, arthritis, coronary artery disease leading to congestive heart failure. Moreover increasing patient awareness and improved healthcare infrastructure in the U.S. and Canada are expected to drive the market of this region at a rapid rate.. Get More Details About Congestive Heart Failure Treatment Devices Market ...
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Volume overload is central to the pathophysiology of most episodes of acute decompensated heart failure. Elevated filling pressures are ultimately responsible for many of the signs and symptoms of heart failure. Consequently, the goals of care, particularly in the acute setting, include the relief of congestion. Most patients presenting with severe acute decompensated heart failure have a pulmonary capillary wedge pressure greater than 25 mm Hg.9 In addition, patients whose left and right filling pressures can be reduced during their hospital stay typically experience alleviation of symptoms.30 Patients whose B-type natriuretic peptide level decreases substantially between admission and discharge have a much reduced likelihood of repeat hospital admission.18. As a reflection of the critical role of congestion in acute decompensated heart failure, clinicians rely heavily on diuretic therapy. Of patients with acute decompensated heart failure followed in recent large registries, 90% received loop ...
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A cardiologist from the UPMC Heart and Vascular Institute has established an advanced heart failure clinic at UPMC Horizon.. Michael A. Mathier, MD, director of the UPMC Pulmonary Hypertension Program and Cardiovascular Fellowship Program, as well as medical director of the Community Outreach and Cardiovascular Health Program, operates the clinic at UPMC Horizon once a month. The clinic was designed to provide consultative services to UPMC Horizon physicians and offers an array of medical and surgical options for advanced heart failure patients ranging from medications, mechanical circulatory support devices and cardiac transplantation.. Dr. Mathier specializes in the care of patients with advanced heart failure, cardiac transplantation, and pulmonary hypertension. He is certified by the American Board of Internal Medicine in internal medicine, cardiology, advanced heart failure, and transplantation.. The advanced heart failure clinic at UPMC Horizon provides a connection to the UPMC Heart ...
ADHF - Acute Decompensated Heart Failure. Looking for abbreviations of ADHF? It is Acute Decompensated Heart Failure. Acute Decompensated Heart Failure listed as ADHF
TY - JOUR. T1 - New-Onset Heart Failure and Mortality in Hospital Survivors of Sepsis-Related Left Ventricular Dysfunction. AU - Vallabhajosyula, Saraschandra. AU - Jentzer, Jacob C.. AU - Geske, Jeffrey B.. AU - Kumar, Mukesh. AU - Sakhuja, Ankit. AU - Singhal, Akhil. AU - Poterucha, Joseph T.. AU - Kashani, Kianoush. AU - Murphy, Joseph G.. AU - Gajic, Ognjen. AU - Kashyap, Rahul. PY - 2017/7/19. Y1 - 2017/7/19. N2 - BACKGROUND:: The association between new-onset left ventricular (LV) dysfunction during sepsis with long-term heart failure outcomes is lesser understood. METHODS:: Retrospective cohort study of all adult patients with severe sepsis and septic shock between 2007 and 2014 that underwent echocardiography within 72?hours admitted to the intensive care unit. Patients with prior heart failure, LV dysfunction, and structural heart disease were excluded. LV systolic dysfunction was defined as LV ejection fraction ,50% and LV diastolic dysfunction as ≥grade II. Primary composite outcome ...
How is Mortality Assessment in Congestive Heart Failure (study; Journal of Clinical Cardiology) abbreviated? MACH-1 stands for Mortality Assessment in Congestive Heart Failure (study; Journal of Clinical Cardiology). MACH-1 is defined as Mortality Assessment in Congestive Heart Failure (study; Journal of Clinical Cardiology) somewhat frequently.
For the millions of people in the United States living with heart failure, managing the condition can be difficult. We recognizes that people with heart failure need extra time, medical attention and education to help keep them healthy and out of the hospital. To help, weve created the Little Company of Mary Heart Failure Clinic and its already helping area patients live a better life.. Clinic Offers Needed Time, Attention. Little Company of Mary Hospital opened the Heart Failure Clinic in May 2013. The clinic helps patients with severe heart failure, such as those who experience shortness of breath at rest or with minimal exertion. Heart failure often is a condition in which the hearts pumping ability is weak. As a result, its unable to pump enough blood to meet the bodys needs. People can develop the condition as a result of a heart attack, coronary heart disease, high blood pressure, kidney disease or other factors. Because people with heart failure often experience a domino effect of ...
Data suggest that the addition of hydralazine and isosorbide dinitrate to the therapeutic regimen of digoxin and diuretics in patients with chronic congestive heart failure can have a favorable effect on left ventricular function and mortality. (From Abstract). ...
Cardiovascular mortality is decreasing in most industrial countries, however mortality for congestive heart failure is increasing. The most important predictors of mortality in heart failure patients are depressed left ventricular function, severity of symptoms (NYHA class), and ventricular conduction abnormality manifested as wide QRS. Recent advances in pharmacological therapy including ACE inhibitors, beta-blocker and spironolactone have resulted in improvement of symptoms and reduction in mortality. Population epidemiological studies demonstrated that mortality and hospitalization rate for heart failure remains very high despite recent pharmacological therapeutic progress. Recent short-term clinical trials demonstrated that cardiac resynchronization therapy (CRT) is effective in improving symptoms of heart failure, functional capacity and quality of life in patients with moderate to severe heart failure and conduction abnormality optimally treated with drug therapy. However, the data for ...
Cardiovascular mortality is decreasing in most industrial countries, however mortality for congestive heart failure is increasing. The most important predictors of mortality in heart failure patients are depressed left ventricular function, severity of symptoms (NYHA class), and ventricular conduction abnormality manifested as wide QRS. Recent advances in pharmacological therapy including ACE inhibitors, beta-blocker and spironolactone have resulted in improvement of symptoms and reduction in mortality. Population epidemiological studies demonstrated that mortality and hospitalization rate for heart failure remains very high despite recent pharmacological therapeutic progress. Recent short-term clinical trials demonstrated that cardiac resynchronization therapy (CRT) is effective in improving symptoms of heart failure, functional capacity and quality of life in patients with moderate to severe heart failure and conduction abnormality optimally treated with drug therapy. However, the data for ...
Paris, France - 30 April 2017: Death in patients with heart failure is inversely related to the wealth of the country they live in, according to late breaking results from the INTERCHF study presented today at Heart Failure 2017 and the 4th World Congress on Acute Heart Failure.1 Death rates in India and Africa were three to four times higher than those documented in Western countries.. Heart failure is a common condition that causes morbidity and mortality worldwide, said lead author Dr Hisham Dokainish, a principal investigator at the Population Health Research Institute (PHRI), McMaster University, Hamilton, Canada.. Most data on heart failure have come from Western countries but the majority of the worlds population lives elsewhere, he continued. This study was conducted to fill large gaps in knowledge about congestive heart failure in non-Western countries.. The International Congestive Heart Failure (INTERCHF) study was an observational cohort study that enrolled 5 823 patients with ...
The enormous costs of mortality and hospitalisation among patients with decompensated chronic heart failure needs to be faced head-on to avoid spiralling healthcare costs, delegates will be warned this morning.. This stark message will form part of the final in-depth session at Heart Failure 2016 looking at key sections of the new ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure, developed with the Heart Failure Association (HFA).. This mornings symposium, which will focus on chronic heart failure and its management, will examine the issues surrounding the management of decompensated chronic heart failure, as well as changes in the management pathway of chronic heart failure patients in general.. Chaired by Gerasimos Filippatos (University of Athens, Greece) alongside Stefan D. Anker (University Medical Center Göttingen, Germany), this mornings session will emphasise the differences between the current recommendations for chronic heart failure and those ...
By traditional methods, congestive heart failure treatment generally includes proper diet, a regimen of medicine and modified daily activities. For congestive heart failure treatment, there are a range of options. In a lot of cases surgery is the best congestive heart failure treatment. When a heart valve ceases to open .... Read More » ...
April Flowers for redOrbit.com - Your Universe Online. The American Heart Association (AHA) issued a statement this week that predicts the number of people with heart failure could rise 46 percent - from 5 million in 2012 to 8 million in 2030 - and that the direct and indirect costs to treat heart failure could more than double -- from $31 billion in 2012 to $70 billion in 2030. This means every US taxpayer could be paying $244 a year to care for heart failure patients by 2030. The statement was published online in the journal Circulation: Heart Failure.. If we don´t improve or reduce the incidence of heart failure by preventing and treating the underlying conditions, there will be a large monetary and health burden on the country, said Paul A. Heidenreich, MD, MS, a professor of medicine at Stanford University School of Medicine.. The costs will be paid for by every adult in this country, not just every adult with heart failure, said Heidenreich, who is also director of the Chronic Heart ...
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Heart failure treatment is only able to reduce the symptoms as heart failure is a chronic disease. Treatment depends on your symptoms and the cause.
TY - JOUR. T1 - The relevance of heart failure severity for treatment with evidence-based pharmacotherapy in general practice. AU - Pont, Lisa G.. AU - Van Gilst, Wiek H.. AU - Lok, Dirk J A. AU - Kragten, Hans J A. AU - Haaijer-Ruskamp, Flora M.. PY - 2003/3. Y1 - 2003/3. N2 - Aims: Internationally, research indicates that pharmacotherapy for chronic heart failure (CHF) is sub-optimal. Traditionally, assessment of drug use in heart failure has focused on the use of individual agents irrespective of CHF severity. This study investigates drug use for CHF patients in general practice with respect to the available evidence, incorporating both disease severity and the use of combination drug regimes. Methods and results: A cross-sectional survey of 769 Dutch CHF patients was performed as part of IMPROVEMENT of HF study. For each New York Heart Association severity classification the minimum treatment appropriate for the heart failure severity according to the scientific evidence available at the ...
Whereas cardiac cachexia is well recognized, the frequency and hemodynamic correlates of malnutrition in severe congestive heart failure (CHF) have not been established. Anthropometric and serum albumin assessment of nutritional status was compared with hemodynamic, echocardiographic and serum chemi …
Background. Many patients with chronic heart failure (CHF) fail to respond to maximal heart failure therapy and progress to end stage heart failure with frequent hospitalizations, poor quality of life and chronic renal insufficiency which leads to progressive chronic kidney disease (CKD) due to long standing renal vasoconstriction. These patients may also die of cardiovascular complications within a short time. Anemia is common in both heart failure and chronic kidney disease and is associated with a marked increase in mortality and morbidity in both conditions. Greater CHF severity has been observed in patients with lower hemoglobin. A decrease in hemoglobin over time is associated with an increase in left ventricular mass and higher mortality. Each of these conditions, that is, anemia, chronic renal insufficiency and heart failure can cause or worsen the other and this vicious circle is known as the Cardio Renal Anemia syndrome (CRAS). This study proposed to document the prevalence of anemia ...
Holy Cross Hospital is a designated LVAD (Left Ventricular Assist Device) shared care facility in South Florida. We help previously end stage heart failure patients through LVAD, cardiac and heart failure management while they are traveling or moving to South Florida, away from their implantation sites. Located in Broward County, we work closely with implant sites around the United States to ensure good quality of life and peace of mind for you as you travel ...
By 2030, several million more people will suffer from heart failure, and related total treatment costs will more than double, from 2012 levels, says the American Heart Association (AHA) in a policy statement published online April 24 ahead of print in Circulation: Heart Failure.. AHA estimated future costs of heart failure (HF) using a methodology that it developed to project the epidemiology and future costs of HF from 2012 to 2030. The model did not double-count costs associated with comorbid conditions and assumed that heart failure rates based on sex, age, and race/ethnicity will not vary, and increasing costs and technological innovation will not vary. AHA projected that by 2030, more than 8 million people will suffer from heart failure; real total direct medical costs related to heart failure will increase from $21 billion to $53 billion; and total treatment costs will increase from $31 billion to $70 billion.. The statement authors concluded, The estimated prevalence and cost of care ...
Our cardiac team in Richmond provides comprehensive heart failure treatment, helping patients manage their symptoms and regain quality of life.
എന്റെ പേര് ശശി , 60 വയസ്സുള്ള ഞാൻ സ്വന്തമായി കാന്റീൻ നടത്തുകയാണ്. 10 അടി നടന്നാൽ കാലു കഴപ്പും നട്ടെല്ല് മുറിയുന്നതുപോലെ വേദനയും, നെഞ്ചിൽ പുകച്ചിലും , കിതപ്പും, കുമ്പിട്ടാൽ കണ്ണ് മൂടലും, തലകറക്കവും , ശരീരം മുഴുവൻ ചൂടും, നെഞ്ച് വേദനയും, നെഞ്ചിടിപ്പും, നെഞ്ചെരിചിലും , നെഞ്ചിൽ ഭാരവും കലശലായി ഉണ്ടായിരുന്നു. എന്റെ ഹൃദയ മസിലിനു ബലക്ഷയം ഉണ്ടെന്നും , ഹൃദയത്തിലേക്കും , തലയിലേക്ക് പോകുന്ന ...
The bodies of four dogs with experimental congestive heart failure and of four normal dogs were homogenized. Analyses for water, fat, sodium, potassium, chloride, and nitrogen were carried out after discarding ascitic fluid in the animals with heart failure. Sodium and chloride concentrations were increased in dogs with heart failure. Otherwise the two groups did not differ significantly.. ...
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TY - JOUR. T1 - Nationwide Frequency and Association of Heart Failure on Stroke Outcomes in the United States. AU - Divani, Afshin A. AU - Vazquez, Gabriela. AU - Asadollahi, Marjan. AU - Qureshi, Adnan I. AU - Pullicino, Patrick. PY - 2009/2/1. Y1 - 2009/2/1. N2 - Background: Few studies of the effect of heart failure (HF) on stroke outcomes have been published. This study was designed to determine the association of co-existing HF with in-hospital length-of-stay (LOS), cost, and mortality among acute stroke patients admitted to hospitals in the United States (US). Methods and Results: All patients with a primary diagnosis of stroke admitted to the US hospitals in calendar years 1995 and 2005 were extracted using the National Inpatient Sample (NIS) database. Patients were categorized based on a secondary diagnosis of HF. Patients demographics, LOS, in-hospital death, disposition, and hospitalization costs were determined. The odds ratio of in-hospital mortality rates for stroke patients with ...
TY - JOUR. T1 - The Impact of Exercise Training on Conduit Artery Wall Thickness and Remodeling in Chronic Heart Failure Patients. AU - Maiorana, A.J.. AU - Naylor, Louise. AU - Exterkate, A.. AU - Swart, A.. AU - Thijssen, D.H.J.. AU - Lam, K.. AU - ODriscoll, G.. AU - Green, Daniel. PY - 2011. Y1 - 2011. N2 - Exercise training is an important adjunct to medical therapy in chronic heart failure, but the extent to which exercise impacts on conduit artery remodeling is unknown. The aim of this study was to evaluate the impact of aerobic and resistance exercise training modalities on arterial remodeling in patients with chronic heart failure. We randomized 36 untrained subjects with chronic heart failure to resistance training (58.8 +/- 3.5 years), aerobic training (61.3 +/- 2.8 years), or an untrained control group (64.4 +/- 2.4 years). Peak oxygen consumption during cycle ergometry increased after 12 weeks in both the resistance and aerobic training (P. AB - Exercise training is an important ...
Heart failure has quickly become one of the top causes of morbidity and mortality accounting for 1 in 9 deaths. As patients with coronary artery disease live longer, survive myocardial infarctions, and bypass surgery, more live with heart failure. The disease has a staggering mortality rate of over 50% within 5 years of diagnosis. The most recent American College of Cardiology (ACC) guideline revised the terminology from the old systolic and diastolic heart failure to heart failure with preserved (HfpEF) or reduced (HFrEF) ejection fraction. The etiology and treatment of HFpEF and HFrEF are significantly different and both patients and providers can become confused on how to treat each condition. In 2017, the ACC released new heart failure guidelines that incorporated the new terminology and recent practice-changing evidence such as the PARADIGM-HF trial which demonstrated significant mortality reduction via the novel neprilysin inhibitor (ARNI), sacubitril. Recent updates have further ...
women suffering from hypertension are at an increased risk of heart failure within the six weeks after delivery, also known as the postpartum period.. Heart failure is a leading cause of maternal morbidity and death, affecting relatively young reproductive-age women, especially among those with the presence of an additional disease or condition, such as hypertension.. The recent clinical research study found that although less than two per cent of all pregnancy-related hospitalisations occurred during the postpartum period, nearly 60 per cent of pregnancy related heart failure hospitalisations took place during the same time.. In the study, published in the journal Circulation: Heart Failure, the team analysed more than 50 million pregnancy-related hospitalisations.. The results showed that there was a 7.1 per cent increase each year in heart failure diagnoses among postpartum hospitalisations.. In addition, heart failure rates during the antepartum period, or prior to delivery, increased by an ...
Heart failure is a clinical syndrome, learn about Heart Failure Diagnosis and Investigation on our Heart Failure Diagnosis and Investigation page
Whellan, D.J.; Ousdigian, K.T.; Al-Khatib, S.M.; Pu, W.; Sarkar, S.; Porter, C.B.; Pavri, B.B.; O'Connor, C.M., 2010: Combined heart failure device diagnostics identify patients at higher risk of subsequent heart failure hospitalizations: results from PARTNERS HF (Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure) study
End of life is an unfortunate but inevitable phase of the heart failure patients journey. It is often preceded by a stage in the progression of heart failure defined as advanced heart failure, and characterised by poor quality of life and frequent hospitalisations. In clinical practice, the efficacy of treatments for advanced heart failure is often assessed by parameters such as clinical status, haemodynamics, neurohormonal status, and echo/MRI indices. From the patients perspective, however, quality-of-life-related parameters, such as functional capacity, exercise performance, psychological status, and frequency of re-hospitalisations, are more significant. The effects of therapies and interventions on these parameters are, however, underrepresented in clinical trials targeted to assess advanced heart failure treatment efficacy, and data are overall scarce. This is possibly due to a non-universal definition of the quality-of-life-related endpoints, and to the difficult standardisation of the ...
TY - JOUR. T1 - Subcutaneous administration of the cardiac hormone BNP in symptomatic human heart failure. AU - Chen, Horng Haur. AU - Redfield, Margaret May. AU - Nordstrom, Lynda J.. AU - Horton, Darlene P.. AU - Burnett, John C Jr.. PY - 2004/4. Y1 - 2004/4. N2 - Background Brain natriuretic peptide (BNP) is a cardiac hormone with vasodilating, natriuretic, renin-angiotensin-aldosterone-inhibiting and lusitropic properties. We have demonstrated that acute subcutaneous (SQ) administration of BNP in experimental congestive heart failure results in elevation of plasma BNP and its second messenger 3′,5′-cyclic guanosine monophosphate (cGMP) with natriuresis and reduction in cardiac filling pressures. Furthermore, chronic subcutaneous BNP in experimental congestive heart failure also resulted in increases in cardiac output and decreases in pulmonary capillary wedge pressure and systemic vascular resistance. Methods The objective of the current study was to assess the safety and efficacy of ...
Heart Failure Management for Nurse Practitioners, Physician Assistants & Primary Care Providers delivers a review of diagnosing & managing heart failure.
According to the American Heart Association, nearly five million Americans are living with heart failure and 550,000 new cases are diagnosed each year. Heart failure is a serious condition that often is misunderstood. The questions below are intended to help clear up some misperceptions about this condition and its complications.. Q. What is heart failure? A. Heart failure does not mean that your heart has stopped or is about to stop. It is a serious condition in which the heart doesnt pump blood through your body as well as it should. Your heart still beats, but it pumps less nutrient- and oxygen-rich blood to the rest of your body. Because of this, heart failure can make you feel tired or weak. Heart failure also can cause swelling and fluid buildup in your legs, feet and even your lungs. Fluid buildup in your lungs often is referred to as congestion, which is why heart failure is sometimes called congestive heart failure (CHF). At times, patients may require hospitalization to treat a ...
Closed on Sundays. May 4, 2016 - Explore Carla Nixs board Recipes - Congestive Heart Failure and Diabetic, followed by 361 people on Pinterest. Treatments options include diet, medication, exercise, and weight loss. Chef Don created the first dietary approach to reversing heart disease as well as hypertension. Congestive heart failure effects about 5 million people in the United States and is responsible for more than 300,000 deaths annually, according to the website MedlinePlus. According to Ayurveda congestive heart failure is known as hridya avrodh. Customer Service Source: Allina Healths Patient Education Department, Heart Failure, fifth edition. Add minced garlic and minced habeneros and cook another minute. Dallas, TX 75231 This dog food recipe for congestive heart failure does involve a good amount of prep work. Share. 500 Low Sodium Recipes Lose The Salt Not Flavor In Meals Congestive heart failure the best food tips for heart failure american heart association low salt cookbook 4th ...
In addition to the standard medications listed above, many other drugs may be used in certain kinds of patients. Additional medications may be needed, for example, when a woman has another condition that requires special treatment to prevent heart failure complications, or because standard medications are not enough to control severe heart failure symptoms.. Women who recently had a heart attack may receive aldosterone antagonists, a class of drugs that is similar to ACE inhibitors and ARBs. Aldosterone antagonists can prevent further changes to the hearts structure in patients who have reduced blood flow to the heart, reducing the need for hospitalization and improving survival.. Those with other existing heart disease, such as coronary artery disease, valve disease, or atrial fibrillation will take blood thinning drugs or aspirin to reduce the risk of dangerous blood clots and future heart damage that could make heart failure worse.. Digitalis, a drug that increases the strength of the heart ...
Fingerprint Dive into the research topics of Survival of patients with severe congestive heart failure treated with oral milrinone. Together they form a unique fingerprint. ...
03 November 2011. Positive study results promote a new paradigm in the management of heart failure. In the recently published PROTECT (Pro-BNP Outpatient Tailored Chronic HF Therapy) trial1, a strategy of NT-proBNP guided heart failure care was independently associated with a significant reduction in total cardiovascular events, the primary composite endpoint of the study, which included worsening heart failure, heart failure hospitalization and cardiovascular related death. Patients with chronic systolic heart failure (left ventricular ejection fraction ,40%) were randomized to one of two treatment approaches: a standard-of-care arm, where patients received aggressive guideline-compliant heart failure care, or an NT-proBNP arm, where patients were treated with similar aggressive clinical care, but with a simultaneous goal to decrease and maintaining NT-proBNP concentrations to a level below 1,000 pg/mL, a value which previous studies have shown the cardiovascular event risk in heart failure to ...
At the Stony Brook Heart Failure and Cardiomyopathy Center, we recognize that excellent heart failure care involves putting you in control of your condition with the help of your dedicated heart failure team. For many patients, heart failure is a chronic condition that requires long-term, well-managed care with doctors and nurses specially trained to evaluate and treat even the most complex forms of heart failure.. What is Cardiomyopathy?. Cardiomyopathy is any disease of the heart muscle that impairs the ability of the heart to pump normally. Cardiomyopathy may result in heart failure, where the heart cant pump as much blood as the body needs.. What is Heart Failure?. Heart failure means that your heart is not pumping blood through the heart and around the body as well as it should. It does not mean that your heart has stopped or is about to stop. In a healthy heart, the strong muscular walls both squeeze and relax in order to pump blood throughout the body. Learn more about heart failure ...
The Canberra Heart Study findings are a wake-up call to those unaware of the extent of the condition. Chronic heart failure is a major and growing public health issue that affects all Western countries. Accordingly, many countries (eg, Scotland1 and Sweden2) systematically monitor its population prevalence and overall impact on the health care system. However, public awareness of the condition remains low.3 Unfortunately, in Australia, apart from sporadic initiatives such as the NSW Chronic Care Collaborative, heart failure remains the Cinderella of health issues - hardly registering on the radar of key health care providers, regulators, relevant government bodies and the general public. For example, less than one in five eligible patients receives specialist heart failure management after hospitalisation for acute heart failure.4 Undoubtedly this is at least partly explained by the fact that we do not know the true magnitude of the problem in Australia. It is time for us to recognise heart ...
An updated guideline adds two new types of drugs to the list of treatment options for heart failure.. In people with the condition, the heart cant pump enough blood throughout the body.. The two new treatments in the updated guidelines are an angiotensin receptor-neprilysin inhibitor (valsartan/sacubitril), sold as Entresto, and a sinoatrial node modulator (ivabradine), sold as Corlanor, according to the American College of Cardiology, the American Heart Association and the Heart Failure Society of America.. Previously recommended drugs for these patients include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, beta blockers and diuretics.. Treatment options for patients with heart failure have expanded considerably. There is more hope than ever before for patients with heart failure, guideline update committee vice chair Dr. Mariell Jessup said in a news release from the heart groups. She is a professor of medicine at the University of Pennsylvania School of ...
TY - JOUR. T1 - Influence of predictive modeling in implementing optimal heart failure therapy. AU - Prasad, Hari. AU - Sra, Jaspinder. AU - Levy, Wayne C.. AU - Stapleton, Dwight D.. PY - 2011/3. Y1 - 2011/3. N2 - INTRODUCTION: A gap remains between evidence-based guidelines in the treatment of heart failure (HF) and current pharmacologic and device therapy. The Seattle Heart Failure Model (SHFM) is an accurate predictive tool that allows the clinician to quantitatively assess the influence of pharmacologic and device therapy on HF. The authors hypothesized that graphically demonstrating the improvement in survival using such a tool may well modify physician practice behavior. METHODS:: The authors examined 50 randomly selected patients from 10 primary care physicians having HF with a left ventricular ejection fraction ,40%. Twenty-one data elements were entered into the SHFM to create a survival estimate before and after implementation of interventions known to be beneficial, both ...
Clinical trial for Acute Myocardial Infarction , Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI
Congestive heart failure[edit]. A systematic review of the literature on home monitoring for heart failure patients indicates ... Published by the New England Journal of Medicine, a randomized controlled trial involving congestive heart failure patients ... "Telemonitoring in patients with heart failure". N Engl J Med. 363: 2301-2309. doi:10.1056/nejmoa1010029.. ... "A systematic review of the literature on home monitoring for patients with heart failure". J Telemed Telecare. 12 (5): 234-41. ...
Congestive heart failure[edit]. Congestive heart failure frequently presents with shortness of breath with exertion, orthopnea ... In 85% of cases it is due to asthma, pneumonia, cardiac ischemia, interstitial lung disease, congestive heart failure, chronic ... Thus, poor ventilation leading to hypercapnia, left heart failure leading to interstitial edema (impairing gas exchange), ... A chest x-ray can be useful to differentiate pneumonia from congestive heart failure.[2] As the cause is usually a bacterial ...
12.4 Medicines used in heart failure. *12.5 Antithrombotic medicines *12.5.1 Anti-platelet medicines ...
On December 7, 1975, just nine days shy of his 72nd birthday, Albright died from congestive heart failure in Mission Viejo, ...
Heart failure[45]. Singer, lyricist, and leader of the Doors. 7004100690000000000♠27 years, 207 days. [31][32][21][34][22][39] ... Heart failure. Drag queen, singer, television personality, and classically trained dancer. 7004101500000000000♠27 years, 289 ... Kidney failure. Founding member of the R&B group 702. 7004101840000000000♠27 years, 323 days. [58]. ... Heart attack. R&B and gospel singer. 7004100450000000000♠27 years, 183 days. [35]. ...
On 18 October 1975 at the age of 33, Graham Haberfield died from heart failure caused by natural causes. He made two episodes ...
Heart failure See also[edit]. *Integrated Security Unit. *Niagara Parks Police Service ...
Heart failure. Enterovioform (clioquinol). Amoebiasis. Eucreas/Galvus Met (vildagliptin/metformin). Diabetes mellitus type 2. ... "Novartis 1Q profit jumps 12 percent as heart drug sales soar". Business. The Seattle Times. Associated Press. 19 April 2018. ... three drugs for heart conditions - Diovan (the company's top-selling product), Exforge, and Tekturna; Sandostatin, a drug to ... Swiss Giant Stands by Heart Medicine Diovan Archived 13 October 2013 at the Wayback Machine. ...
She died on 4 January 2018, aged 72, from heart failure.[5] ...
Alice Trillin died on September 11, 2001, at the New York Presbyterian Hospital from heart failure resulting from radiation ...
They were married until her death of congestive heart failure on September 28, 2005, fourteen days after her 84th birthday, at ... 2005 in New York City of congestive heart failure.[5] ...
"Renal consequences of prostaglandin inhibition in heart failure". Heart Failure Clinics. 4 (4): 505-10. doi:10.1016/j.hfc. ... the heart and brain.[1][2][3][4] It can be autosomal dominant or autosomal recessive, with the autosomal dominant form being ... and norepinephrine which increase blood output from the heart and constrict arteries. People with neurogenic hypertension ...
"Heart Failure Society of America (HFSA) 2006 Comprehensive Heart Failure Practice Guideline". J Cardiac Failure. 12 (1): e1- ... In the developed world, the most common cause is liver cirrhosis.[3] Other causes include cancer, heart failure, tuberculosis, ... Those with ascites due to heart failure may also complain of shortness of breath as well as wheezing and exercise intolerance. ... 2005). "ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the ...
... or venous stasis which may occur in heart failure,[22] or after long periods of sedentary behaviour, such as sitting on a long ... "Journal of the American Heart Association. 8 (6). doi:10.1161/JAHA.118.011272. ISSN 2047-9980. PMC 6475051.. ... "European Heart Journal: ehw145. doi:10.1093/eurheartj/ehw145. ISSN 0195-668X. PMC 5381598.. ... In people with a "shunt" (a connection between the pulmonary and systemic circulation), either in the heart or in the lung, a ...
Heart Failure. 2 (5): 482-489. doi:10.1161/CIRCHEARTFAILURE.109.852228. ISSN 1941-3297. PMID 19808379.. ... which in the heart may contribute to weakness of the heart muscle or abnormal heart rhythms. The alterations seen in disease ... Heart failure can also cause the near-complete loss of T-tubules from atrial cardiomyocytes, reducing atrial contractility and ... and are also disrupted in the ventricles of patients with heart failure, contributing to reduced force of contraction and ...
Congestive heart failure. Resting place. Astana Giribangun. Nationality. Indonesian. Political party. Golkar. ... "Asia-Pacific - Suharto has multiple organ failure". Al Jazeera English. 14 January 2008. Retrieved 14 April 2010.. ... After resigning from the presidency, Suharto was hospitalised repeatedly for stroke, heart, and intestinal problems. His ... and partial renal failure.[124] His health fluctuated for several weeks but progressively worsened with anaemia and low blood ...
... for patients with heart failure, and 25% for patients with heart monitoring outside the ICU. Another study, of advanced cancer ... creation of septal defect in heart Blalock-Hanlon procedure. shunt from heart chamber to blood vessel. atrium to pulmonary ... American Heart Association Archived 2012-02-17 at the Wayback Machine *^ American Heart Association, Ad Council launch Hands- ... "Highlights of the 2010 American Heart Association Guidelines for CPR and ECC" (PDF). American Heart Association. Archived (PDF) ...
... or venous stasis which may occur in heart failure,[19] or after long periods of sedentary behaviour, such as sitting on a long ... In people with a "shunt" (a connection between the pulmonary and systemic circulation), either in the heart or in the lung, a ... This restriction gives an insufficient supply of oxygen to the heart muscle which then results in tissue death,(infarction). A ... Myocardial infarction (MI) or heart attack, is caused by ischemia, (restriction in the blood supply), often due to the ...
Congestive heart failure. *Cortical proliferation of long bones. *Diarrhea. *Disseminated intravascular coagulation ... it is said to be usable by men suffering from diabetes or heart problems and those who have undergone a prostatectomy.[10] It ... In babies with congenital heart defects, it is used by slow injection into a vein to open the ductus arteriosus until surgery ... hypoplastic left heart syndrome, pulmonary atresia/stenosis, tricuspid atresia/stenosis, transposition of the great arteries) ...
... renal failure, heart attack, stroke and heart failure. Depression with suicidal ideation may develop in heavy users. Finally, a ... This can lead to death from acute myocardial infarction, respiratory failure, stroke, cerebral hemorrhage, or heart failure. ... However, the long-term effect of cocaine use and development of heart failure, with early mortality, high morbidity, and ... Heart Failure Reviews. 19 (6): 815-824. doi:10.1007/s10741-014-9418-y. ISSN 1573-7322. PMID 24398587. Walsh, David W.; McVey, ...
Congestive heart failure[edit]. Although beta blockers were once contraindicated in congestive heart failure, as they have the ... stable congestive heart failure; in cases of acute decompensated heart failure, beta blockers will cause a further decrease in ... and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure ( ... Cruickshank JM (2010). "Beta-blockers and heart failure". Indian Heart Journal. 62 (2): 101-10. PMID 21180298.. ...
Shaikh AY, Shih JA (Jun 2012). "Chemotherapy-induced cardiotoxicity". Current Heart Failure Reports. 9 (2): 117-27. PMID ... Cardiotoxicity (heart damage) is especially prominent with the use of anthracycline drugs (doxorubicin, epirubicin, idarubicin ... Female infertility by chemotherapy appears to be secondary to premature ovarian failure by loss of primordial follicles.[91] ... Humphreys BD, Soiffer RJ, Magee CC (Jan 2005). "Renal failure associated with cancer and its treatment: an update". Journal of ...
High volume hyponatremia can occur from heart failure, liver failure, and kidney failure.[3] Conditions that can lead to ... Hypervolemic hyponatremia is most commonly the result of congestive heart failure, liver failure, or kidney disease. ... Chatterjee, Kanu; Anderson, Mark; Heistad, Donald; Kerber, Richard E. (30 May 2014). Manual of Heart Failure. JP Medical Ltd. p ... or heart failure who fail limiting fluid intact.[32] In Europe they are not generally recommended.[32] ...
But if the heart begins to fail (a condition known as congestive heart failure) the pressure changes can cause very severe ... The heart[edit]. The pumping force of the heart should help to keep a normal pressure within the blood vessels. ... Faris, R.F.; Flather, M.; Purcell, H.; Poole-Wilson, P.A. & Coats, A.J. (15 February 2012). "Diuretics for heart failure". The ... Exercise helps the leg veins work against gravity to return blood to the heart. If blood travels too slowly and starts to pool ...
Congestive heart failure - 15%. *Emphysema/COPD - 6%. *Stroke/cardiovascular accident - 5%. *Diabetes - 3% ... kidney failure, COPD, and others. The program also piloted a "Breakfast Program" to provide nutritionally sound breakfast meals ...
risk of heart failure. Side effects in women[edit]. Side effects in women include:[87] ... I felt my heart skip a beat. I had never seen so many fireworks together. With a soigneur we counted the pills: there were ... Among the treatments they supplied was nitroglycerine, a drug used to stimulate the heart after cardiac attacks and which was ...
... she died from heart failure while under respiratory support due to emphysema, aged 79,[28] at her home in Switzerland.[26] She ... She signed a contract with David O. Selznick and appeared with Janet Gaynor in the comedy The Young in Heart (1938) before ... Selznick was pleased with Goddard's performances, particularly her work in The Young at Heart, and considered her for the role ...
... heart failure. Daniel Johnston, 58, American singer-songwriter ("Walking the Cow") and visual artist, heart attack. Annette ... heart failure. Sid Haig, 80, American actor (The Devil's Rejects, Jason of Star Command, THX 1138), complications from a lung ... heart failure. Wayne Brown, 88, Canadian ice hockey player (Boston Bruins, Seattle Bombers, Tacoma Rockets). Myles Burnyeat, 80 ... heart failure. Olav Skjevesland, 77, Norwegian Lutheran prelate, Bishop of Agder og Telemark (1998-2012). Carlos Squeo, 71, ...
Thomas N. Schroth, 88, American editor (Congressional Quarterly), founder of The National Journal, heart failure. José Carlos ... Mollie Sugden, 86, British actress (Are You Being Served?), heart failure. Rupert Thorneloe, 39, British soldier, Commanding ... Marcey Jacobson, 97, American photographer of indigenous peoples in Mexico, heart failure. James E. King, 69, American ... John Keel, 79, American ufologist and writer (The Mothman Prophecies), heart failure. Barbara Margolis, 79, American prisoners ...
Nina Cassian, 89, Romanian poet, heart attack. Joe Curl, 59, American basketball coach (University of Houston), heart failure. ... Hal Cooper, 91, American television director and producer (I Dream of Jeannie, Maude, Gimme a Break!), heart failure. Edna Doré ... Wayne Henderson, 74, American jazz trombonist (The Jazz Crusaders) and record producer, heart failure. Rhondda Alder Kelly, 87 ... Stanislaus Okurut, 84, Ugandan politician, Minister of Labour, Sports and Transport, heart failure. John Pinette, 50, American ...
T]he panel's decision striking down Sequenom's noninvasive prenatal test strikes at the very heart of the patent system. ... He blames the assertedly disastrous result on the Federal Circuit's failure to "consider the claim as a whole," instead of ...
The primary failure is the absence of growth of the brain, rendering the sutures of the cranial vault useless.[16] As a ... heart, central nervous system or the respiratory tract,[12] you may speak of a syndromic form of craniosynostosis. More than ...
Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA. December 2011, 306 (23): 2594-605. PMC ... IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts. Cellular Physiology and Biochemistry. 2016, 38 ...
Hyperosmolar hyperglycemic state, diabetic ketoacidosis, heart disease, strokes, diabetic retinopathy, kidney failure, ... "Global Heart. 14 (3): 215-240. doi:10.1016/j.gheart.2019.07.009. ISSN 2211-8179. PMID 31451236.. ... Gardner, C; Wylie-Rosett, J; Gidding, SS; Steffen, LM; Johnson, RK; Reader, D; Lichtenstein, AH; American Heart Association ... kidney failure, and poor blood flow in the limbs which may lead to amputations.[1] The sudden onset of hyperosmolar ...
After at least six failures, he was admitted in September 1609. He became a prosperous London doctor, serving as Censor of the ... so was the heart to mankind. The sun conveyed Spirit to the earth through its rays, which circulated in and about the earth ...
In 1937, she returned to the stage in well-received productions of Noël Coward's Tonight at 8.30, The Astonished Heart, and ... Louis (1944), the studio allowed her to debut on Broadway in Many Happy Returns (1945). The play was a failure, but Astor ... She starred on Broadway again in The Starcross Story (1954), another failure and returned to Southern California in 1956. She ... Before Helen Langhanke died of a heart ailment in January 1947, Astor said she sat in the hospital room with her mother, who ...
Biogenesis of lamin A in normal cells and the failure to generate mature lamin A in HGPS. In the setting of ZMPSTE24 deficiency ... Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology. 2004, 5 (2): 98-111. PMID ...
American Heart Journal. 150 (5): 933.e1-933.e7. doi:10.1016/j.ahj.2005.06.005. PMID 16290967.. ... which sometimes may lead to more severe condition including kidney failure ... "Urinary NO3 excretion and renal failure in indinavir-treated patients". Brazilian Journal of Medical and Biological Research ...
On 15 April 1998, Pol Pot died in his sleep, apparently of heart failure.[398] His body was preserved with ice and formaldehyde ... The failure of Cambodian troops in the Eastern Zone to successfully resist the Vietnamese incursion made Pol Pot suspicious of ... fearing that they would be criticised for failure.[275] The government became aware of this, and by the end of 1976 Pol Pot ... acknowledged food shortages in three quarters of failure.[275]. Members of the Khmer Rouge received special privileges not ...
... congestive heart failure, COPD (chronic obstructive pulmonary disease), renal failure, and severe burns; patients who have " ... which is a syndrome that is a co-morbidity of cancer and congestive heart failure; chronic obstructive pulmonary disease; burns ... Brown atrophy of the heart Effect of spaceflight on the human body Muscle weakness Muscular dystrophy Myotonic dystrophy ... liver failure, etc., and the wasting Dejerine-Sottas syndrome (HMSN Type III). Glucocorticoids, a class of medications used to ...
He died of pneumonia and heart failure due to septicaemia in the hospital's intensive care unit on 4 January 1986, at the age ... Then when I leave I give him a kick... for breaking my heart." ... "Dear Miss Lonely Hearts" Solo in Soho 32[93]. "King's Call" 35[ ...
Sepsis is caused by overwhelming response to an infection and leads to tissue damage, organ failure, and even death. The ... symptoms include confusion, shortness of breath, elevated heart rate, pain or discomfort, over-perspiration, fever, shivering, ...
Heart-shaped with the notch towards the stalk.. Cuneate. Wedge-shaped.. Hastate. Shaped like an halberd and with the basal ... However, horizontal alignment maximizes exposure to bending forces and failure from stresses such as wind, snow, hail, falling ...
... congestive heart failure; chronic obstructive pulmonary disease; and complications of devices, implants and grafts.[78] ...
The patient population consisted of those with congestive heart failure or acute myocardial infarction. We found no significant ...
Heart failure (due to an increase in venous pressure). *Hematological malignancy (such as leukemia) ...
Ischaemic Heart Disease (9.2%) 3. Lower respiratory infection (7%) 4. Diarrhoeal disease (3.3%) 5. Self harm (3%) 6. ... Introducing breast milk substitutes to infants before age 6 months can contribute to breastfeeding failure. Substitutes, such ...
... es have three hearts; a systemic heart that circulates blood round the body and two branchial hearts that pump it ... This causes death by respiratory failure leading to cerebral anoxia. No antidote is known, but if breathing can be kept going ... after which the blood is pumped through the gills by the auxiliary hearts and back to the main heart. Much of the venous system ... The systemic heart is inactive when the animal is swimming and thus it tires quickly and prefers to crawl.[33][34] Octopus ...
Acute overdose may cause fever, hypoglycemia, heart failure, coma, and unrecognized adrenal insufficiency. ... and fast heart rate.[1] Use is not recommended in people who have had a recent heart attack.[1] Use during pregnancy has been ... Too high a dose of levothyroxine causes hyperthyroidism.[18] Overdose can result in heart palpitations, abdominal pain, nausea ... For older people (over 50 years old) and people with known or suspected ischemic heart disease, levothyroxine therapy should ...
Lauritz' failure to look after the children causes a rift between Agnes and him. She starts a small business at home so she can ... He dies early on from a heart attack, but is widely reported to have killed himself with either a duelling gun or gas. The fate ... " ("Fatty") Hansen (born 1893) - Benny Hansen - A good-hearted painter. He's a corpulent man who is seen eating in almost every ...
... deals with pain and symptom relief and emotional support in patients with terminal illnesses including cancer and heart failure ... "Heart Views. 4 (2).. copy Archived 30 November 2004 at the Wayback Machine. ... "Heart Views. 5 (2): 74-85 [80]. 2004. Archived from the original on 8 March 2013.. ... The anesthesiologist's role during surgery is to prevent derangement in the vital organs' (i.e. brain, heart, kidneys) ...
"Jet Safe After Heart-Stopping, Dead-Engine Dive". Los Angeles Times. 25 June 1982. Archived from the original on 4 June 2011. ... The ash and dust caused extensive damage to the aircraft, including the failure of all four engines.[174] The crew managed to ... On 27 May 2017, British Airways suffered a computer power failure. All flights were cancelled and thousands of passengers were ... McCarran International Airport due to an uncontained engine failure[181] of its left (#1) General Electric GE90 engine, which ...
"The Heart of the Prince" / "Bulma's On the Job! The Vegeta-Remodeling Plan". Transcription: "Buruma ugoku! Bejīta Kaizō keikaku ... Remembering his life with his friends and family on his home planet, and unable to bear his failure to protect them from Baby, ...
November 11 - John Doar, 92, American lawyer and civil rights activist, congestive heart failure.[43] ... November 11 - Harry Lonsdale, 82, American scientist, entrepreneur, and politician, heart failure.[44] ... November 19 - Ramón Hoyos, 82, Colombian racing cyclist, heart attack.[76]. *November 19 - Otieno Kajwang, 55, Kenyan ... November 14 - Adib Jatene, 85, Brazilian cardiologist and politician, Minister of Health (1992, 1995-1996), heart attack.[61] ...
... or congestive heart failure.[37] Another skin condition, found in Europe but not in North America, is borrelial lymphocytoma, a ... the infection may cause heart complications known as Lyme carditis.[37][38] Symptoms may include heart palpitations (in 69% of ... "British Heart Journal. 70 (1): 15-6. doi:10.1136/hrt.70.1.15. PMC 1025222. PMID 8037992.. ... About half the people with Lyme carditis progress to complete heart block, but it usually resolves in a week.[37] Other Lyme ...
In the midst of debate over the Judicial Procedures Reform Bill of 1937, Robinson died of heart failure. ... He died of heart failure.[3] Two days after Robinson's sudden death, stunned colleagues, friends, and family attended his ...
... pneumonia and congestive heart failure. She died on April 26, 2011, at age 60 in Edison, New Jersey.[20] ... Her Live album (2008) featured many of her hits as well as a cover of "Piece of My Heart".[citation needed] ... a Heart; the Nerve". In addition, the concert featured performances by Jewel, Joel Grey, Roger Daltrey, and Jackson Browne, ...
Failure to meet cost targets will lead to substantial losses for an organisation. In addition, with global competition, the R&D ... This includes medical ventilators, incubators, anaesthetic machines, heart-lung machines, ECMO, and dialysis machines. ... In 2017, an article in the policy journal Milbank Quarterly criticized the FDA for its failure to safeguard electronic health ... The electrodes contact the heart directly through the chest, allowing stimulation pulses to pass through the body. Recipients ...
... and heart function.[231] Disruption of this balance may thus be fatal: for example, ingestion of large amounts of potassium ... but they have all met with failure. However, ununennium may not be an alkali metal due to relativistic effects, which are ...
Failure on the Left Side (Left-Ventricular Heart Failure). Failure on the left side of the heart is more common than failure on ... Other diseases that damage or weaken the heart muscle or heart valves can also cause heart failure. Heart failure is most ... Failure on the Right Side (Right-Ventricular Heart Failure). Failure on the right side of the heart is most often a result of ... Heart Failure. Heart failure is a condition in which the heart does not pump enough blood to meet the needs of the bodys ...
Harnessing the T Cell Function as a New Direction in Attenuating the Transition from Left Heart Failure to Right Heart Failure ... Peter Liu, University of Ottawa Heart Institute, Canada Immune System as Sensor/Mediator for Progression in Heart Failure - ... Epigenetic Regulation of Heart Failure. Toshiyuki Ko, University of Tokyo, Japan Short Talk: Single-Cell Analysis of Non- ... Mitochondrial Remodeling in Heart Failure. Rong Tian, University of Washington, USA Metabolic Modulation of Cardiac Hypertrophy ...
Risk assessment for incident heart failure in individuals with atrial fibrillation. Eur J Heart Fail. 2013;15:843-849. PMID ... Heart Failure in Atrial Fibrillation. (10-year risk). (based on Schnabel RB, Rienstra M, Sullivan LM, Sun JX, Moser CB, Levy D ... Cox Proportional Hazards Regression Coefficients for Direct Estimation of Risk of Heart Failure. ... Participants with manifest atrial fibrillation free of heart failure at baseline, aged 39 to 96 years ...
... heart failure/systemic hypertension, heart failure/pulmonary hypertension, heart failure/diabetes, heart failure/kidney failure ... left heart failure versus right heart failure). Right heart failure compromises pulmonary flow to the lungs. Left heart failure ... Congestive heart failure[edit]. Heart failure may also occur in situations of "high output" (termed "high-output heart failure ... 2) Heart failure with preserved ejection fraction (HFpEF). This type is also known as diastolic heart failure or heart failure ...
... interdisciplinary dialogue focused on heart failure, its pathogenesis and treatment. The ... ... Heart Failure Reviews is an international journal which develops links between basic scientists and clinical investigators, ... Heart Failure Reviews. Editors-in-Chief: S. Goldstein; H.N. Sabbah. ISSN: 1382-4147 (print version). ISSN: 1573-7322 ( ... Heart Failure Reviews is pleased to remind authors that unsolicited review articles are always being considered for publication ...
... or heart failure, is a condition in which the heart cant pump enough blood to the bodys other organs. ... Congestive Heart Failure. Congestive heart failure (CHF), or heart failure, is a condition in which the heart cant pump enough ... Learn more about Heart Failure. The Heart Profilers Treatment Decision Tool. Links to Other Sites. Heart Failure message board ... About Heart Transplants booklet. *"What Is Congestive Heart Failure?" and "How Can I Live With Heart Failure?" in Answers By ...
Pooled results from four small studies suggest that testosterone could help heart failure patients exercise more and suffer ... The condition accounts for about a third of heart-related deaths. When a person has heart failure, the heart cannot pump ... The American Heart Association estimates that about 5.7 million Americans have congestive heart failure, about 2 percent of the ... End-stage heart failure can be treated with heart transplants; occasionally, doctors implant a left ventricular assist device ( ...
The Seattle Heart Failure Model (SHFM) is a calculator of projected survival at baseline and after interventions for patients ... NOTE: In addition to the Seattle Heart Failure Model calculator for the web, there are free, downloadable versions for the Mac ... with heart failure. SHFM is designed for use by health care providers knowledgeable in cardiac medicine. Patients should only ...
Roughly 550,000 people are diagnosed with heart failure each year. It is the leading cause of hospitalization in people older ... More Topics Related to Heart Failure. All Directories in Heart Failure. * Advanced Heart Failure ... Guide to Heart Disease. Clogged arteries, heart attack, heart failure, and more. ... Congestive heart failure affects about 5 million Americans. ... Heart Failure: Check Your Weight. *Heart Failure? Eat Less ...
Roughly 550,000 people are diagnosed with heart failure each year. It is the leading cause of hospitalization in people older ... Heart Failure. Heart failure can be caused by coronary artery disease, heart attack, cardiomyopathy, and high blood pressure. ... Heart Failure Symptoms. If you have heart failure, you may not have any symptoms, or the symptoms may range from mild to severe ... Guide to Heart Disease. Clogged arteries, heart attack, heart failure, and more. ...
Cutting Edge Solutions for Heart ProblemsIt is common knowledge that heart diseases account for a significant amount of deaths ... Heart failure heart attack * 1. Cutting Edge Solutions for Heart ProblemsIt is common knowledge that heart diseases account for ... Thus, conditions leading to heart failure (In Frenchinsuffisance cardiaque) are picked up at a very early stage and adequate ... 2. Easy Ways to Keep Your Heart in Good HealthKeeping your heart healthy is very simple provided you are prepared to make a ...
... nurse-led heart failure clinic was created to help heart failure patients better control and self-manage their disease post- ... Nurse-Led Heart Failure Clinic June 2008. Kim Miller, CFNP, manages an off-site nurse-led heart failure clinic that was created ... An off-site, nurse-led heart failure clinic was created to help heart failure patients better control and self-manage their ... Kim Miller, CFNP, manages an off-site nurse-led heart failure clinic that was created to help heart failure patients better ...
Heart failure is a condition in which the heart is no longer able to pump oxygen-rich blood to the rest of the body efficiently ... Congestive heart failure; Left-sided heart failure; Right-sided heart failure - cor pulmonale; Cardiomyopathy - heart failure; ... Heart failure is present when:. *Your heart muscle cannot contract very well. This is called systolic heart failure, or heart ... New, abnormal heart rhythms Most of the time, heart failure is a chronic illness. Some people develop severe heart failure. At ...
Congenital Heart Disease Most common type of heart disease among children a) ~ 1% of live births b) most causes unknown i) ~ 10 ... Congenital heart disease heart failure * 1. ,ul,,li,Congenital Heart Disease ,/li,,/ul,,ul,,li,Most common type of heart ... Right Sided Heart Failure ,/li,,/ul,,ul,,li,Major cause is LEFT heart failure ,/li,,/ul,,ul,,li,Occurs as isolated failure in ... ul,,li,Heart Failure (i.e.,Congestive) ,/li,,/ul,,ul,,li,Heart cannot eject volume which is ,/li,,/ul,,ul,,li,being returned to ...
Health Information on Heart Failure: MedlinePlus Multiple Languages Collection ... Congestive Heart Failure Self-Management Plan - English PDF Congestive Heart Failure Self-Management Plan - Русский (Russian) ... Congestive Heart Failure Self-Management Plan - English PDF Congestive Heart Failure Self-Management Plan - Tiếng Việt ( ... Heart Failure: MedlinePlus Health Topic - English Fallo cardíaco: Tema de salud de MedlinePlus - español (Spanish) ...
Learn the symptoms of congestive heart failure like fatigue; swelling of the legs, ankles, feet, or abdomen; problems sleeping ... This can be referred to as right-sided heart failure as failure of the right-sided heart chambers to pump venous blood to the ... What are congestive heart failure symptoms?. The symptoms of congestive heart failure vary among individuals according to the ... Heart Failure Society Of America. Evaluation and management of patients with acute decompensated heart failure. J Card Fail. ...
Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this ... Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this ... Initial Changes in β-Adrenergic Receptor Function during Development of Rapid Ventricular Pacing-Induced Heart Failure ... Antioxidants and the Heart Pawan K. Singal, Arvinder K. Dhalla, Neelam Khaper, Michael Hill, Thomas P. Thomas, Charita ...
The muscles of the heart become less efficient and damaged, leading to overload on the heart. ... Heart failure is a condition where the heart fails to pump and circulate an adequate supply of blood to meet the requirements ... In heart failure, however, this mechanism fails due to weakened cardiac muscles which results in a failure of the heart to pump ... There are several conditions that can lead to heart failure. One example is heart muscle damage caused by a heart attack or ...
Heart Failure Topics. LifestyleComplicationsDiagnosisMedication. Show More. The Latest. This Triathlete is Living with Heart ... Failure. Doctors arent exactly sure what caused his heart to weaken, but a lack of answers has done little to slow him down. ...
... and learn more about Heart Failure Storylines. Download Heart Failure Storylines and enjoy it on your iPhone, iPad, and iPod ... Heart Failure Health Storylines is developed in partnership with the Heart Failure Society of America, and is powered by the ... Heart Failure Health Storylines provides tools to better manage and monitor heart failure:. MEDICATION REMINDER. Taking your ... and more to help you manage heart failure and congestive heart failure (CHF). Choose what you want to track to build your own ...
Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction - the ... Heart failure with preserved ejection fraction. From Wikipedia, the free encyclopedia. (Redirected from Diastolic heart failure ... Although the term diastolic heart failure is often used when there are signs and symptoms of heart failure with normal left ... Segura, A. M., Frazier, O. H., & Buja, L. M. (2014). Fibrosis and heart failure. Heart failure reviews, 19(2), 173-185. ...
A new study suggests Americans with heart failure may benefit less from recommended medications than patients in other ... Some five million Americans are living with heart failure, in which the heart fails to pump enough blood into the body. The ... It could be a question of different use of medications or devices to control heart failure, or it could be a chance finding ... This really goes beyond the beta blocker and heart failure story, its about how we conduct clinical trials, he said. I think ...
... researchers show that silencing the Hippo signaling pathway can activate heart muscle regeneration. ... In a mouse model of advanced heart failure, ... Heart failure does not mean that the heart has stopped pumping ... At present, the best treatment for heart failure is a heart transplant. However, the number of heart failure patients far ... Heart failure is a serious condition that affects around 5.7 million adults in the United States. It develops when the heart ...
In addition to our heart failure nurse, the OHSU heart failure team has a nurse or heart failure cardiologist on call 24-7. ... OHSU offers Heart Failure University to educate hospitalized patients and families.. Heart failure topics for patients and ... OHSUs Heart Failure Team. Advanced Certification. In February 2015, OHSUs heart failure team received The Joint Commissions ... Caring for patients with heart failure. Heart failure (HF) is one of the most serious conditions primary care providers treat, ...
The physiopathology of the right heart failure is tightly linked to the particular features of the right ventricle (RV). Its ... Ghio S, Tavazzi L. Right ventricular dysfunction in advanced heart failure. Ital Heart J. 2005;6:852-5.PubMedGoogle Scholar ... EuroHeart failure survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population. Eur ... Neurohormonal activation and the chronic heart failure syndrome in adults with congenital heart disease. Circulation. 2002;106: ...
The clinical diagnosis of heart failure can be challenging as signs and symptoms may be non-specific.1 In the United Kingdom ... Patients with symptoms suggestive of heart failure who have had a myocardial infarction or have a raised B-type natriuretic ... Echocardiography remains the imaging modality of choice in confirming a diagnosis of heart failure ... recommend that when heart failure is suspected, the initial investigations listed below are useful in primary care.2 … ...
Physicians need a way to identify complications linked to heart failure in their patients before they occur. New technology can ... Heart failure has reached epidemic proportions, and its not slowing down. From now until 2030, U.S. cases of heart failure ... who specializes in Advanced Heart Failure and Mechanical Circulatory Support. She is a leading expert on novel heart failure ... A proactive approach to heart failure. by Dr. Susan Joseph , Sep 13, 2017, 12:01 AM. Share on Twitter Share on Facebook Email ...
Congestive heart failure (CHF ) is when blood backs up in the heart. ... Heart failure is when the heart cant pump blood the way it should. ... What Is Heart Failure?. Heart failure is when the heart cant pump blood the way it should. If that happens, blood and oxygen ... What Is Congestive Heart Failure?. Congestive heart failure (CHF) is when blood backs up (gets "congested) in the heart. This ...
congenital heart failure wikipedia. conjunctive heart failure wikipedia. left sided heart failure wikipedia. systolic heart ... What is Heart Failure? , American Heart Association. www.heart.org/en/health-topics/heart-failure/... ... the heart doesnt need to be weakened to cause heart failure. It can also occur if the heart becomes too stiff.In heart failure ... Heart failure can be sudden ( acute ), like after a heart attack , or can come on slowly . Someone with heart failure can ...
  • Heart failure ( HF ), often referred to as congestive heart failure ( CHF ), occurs when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs. (wikipedia.org)
  • [2] The term "congestive heart failure" is often used, as one of the common symptoms is congestion , or build-up of fluid in a person's tissues and veins in the lungs or other parts of the body. (wikipedia.org)
  • Congestive heart failure (CHF), or heart failure, is a condition in which the heart can't pump enough blood to the body's other organs. (archive.org)
  • How do you diagnose and treat congestive heart failure? (archive.org)
  • The most common signs of congestive heart failure are swollen legs or ankles or difficulty breathing. (archive.org)
  • Various drugs are used to treat congestive heart failure. (archive.org)
  • When a specific cause of congestive heart failure is discovered, it should be treated or, if possible, corrected. (archive.org)
  • For example, some cases of congestive heart failure can be treated by treating high blood pressure. (archive.org)
  • Most people with mild and moderate congestive heart failure can be treated. (archive.org)
  • The American Heart Association estimates that about 5.7 million Americans have congestive heart failure, about 2 percent of the population. (go.com)
  • Heart failure (HF), also known as congestive heart failure (CHF), (congestive) cardiac failure (CCF), and decompensatio cordis, is when the heart is unable to pump sufficiently to maintain blood flow to meet the body tissues' needs for metabolism. (wikipedia.org)
  • This is called congestive heart failure. (medlineplus.gov)
  • The symptoms of congestive heart failure vary among individuals according to the particular organ systems involved and depending on the degree to which the rest of the body has 'compensated' for the heart muscle weakness . (medicinenet.com)
  • An early symptom of congestive heart failure is fatigue . (medicinenet.com)
  • While fatigue is a sensitive indicator of possible underlying congestive heart failure, it is obviously a nonspecific symptom that may be caused by many other conditions. (medicinenet.com)
  • As the body becomes overloaded with fluid from congestive heart failure, swelling ( edema ) of the ankles and legs or abdomen may be noticed. (medicinenet.com)
  • Developed in partnership with the Heart Failure Society of America, this app makes it easy to record your symptoms, vital signs, medications, and more to help you manage heart failure and congestive heart failure (CHF). (apple.com)
  • This data allows doctors to predict congestive heart failure up to two weeks earlier than they can in patients without sensors. (washingtonexaminer.com)
  • Scientists at the Ohio State University are testing a vest that detects fluid accumulation in the lungs of congestive heart failure patients. (washingtonexaminer.com)
  • Congestive heart failure (CHF) is when blood backs up (gets "congested) in the heart. (kidshealth.org)
  • What Happens in Congestive Heart Failure? (kidshealth.org)
  • What Causes Congestive Heart Failure? (kidshealth.org)
  • In its early stages, congestive heart failure might not cause any symptoms. (kidshealth.org)
  • How Is Congestive Heart Failure Diagnosed? (kidshealth.org)
  • How Is Congestive Heart Failure Treated? (kidshealth.org)
  • If your child has congestive heart failure, it can feel overwhelming. (kidshealth.org)
  • Heart Failure, also known as Congestive Heart Failure, is a clinical syndrome that results from the progressive process of remodeling , in which mechanical and biochemical forces alter the size, shape, and function of the ventricle's ability to pump enough oxygenated blood to meet. (yahoo.com)
  • Heart failure , sometimes known as congestive heart failure , occurs when your heart muscle doesn't pump blood as well as it should. (yahoo.com)
  • People with congestive heart failure are educated to undertake various non-pharmacological measures to improve symptoms and prognosis. (yahoo.com)
  • Learn about topics such as How to Prevent Congestive Heart Failure , How to Recognize Symptoms of Heart Failure Exacerbation , How to Diagnose Heart Failure , and more with our helpful step-by-step instructions with photos and videos. (wikihow.com)
  • ORLANDO, Fla. -- The American College of Cardiology is launching a new initiative to reduce the number of patients who are readmitted to hospitals within 30 days of being discharged for congestive heart failure or a heart attack. (wsj.com)
  • J. Butler, "Risk factors for heart failure," in Congestive Heart Failure , J. D. Hosenpud and B. H. Greenberg, Eds. (hindawi.com)
  • Predictors of congestive heart failure in the elderly: the cardiovascular health study," Journal of the American College of Cardiology , vol. 35, no. 6, pp. 1628-1637, 2000. (hindawi.com)
  • Survival associated with two sets of diagnostic criteria for congestive heart failure," American Journal of Epidemiology , vol. 160, no. 7, pp. 628-635, 2004. (hindawi.com)
  • Congestive heart failure incidence and prognosis: case identification using central adjudication versus hospital discharge diagnoses," Annals of Epidemiology , vol. 16, no. 2, pp. 115-122, 2006. (hindawi.com)
  • Congestive heart failure is when this lack of function begins affecting the lungs ability to function normally by filling the alveoli with fluid. (ipl.org)
  • Congestive Heart Failure Acute Decompensated Heart Failure (ADHF) is a clinical syndrome of worsening signs or symptoms of heart failure requiring hospitalization or other unscheduled medical care (Felker 2014). (ipl.org)
  • ADHF formerly known as congestive heart failure is one of the leading cause for hospitalizations in the United States. (ipl.org)
  • Congestive heart failure The term 'congestive heart failure' is somewhat misleading. (ipl.org)
  • Data from randomized trials support the ability of co-enzyme Q10 (CoQ10) to improve heart function in people with congestive heart failure (CHF), say scientists from Tulane University in New Orleans. (nutraingredients-usa.com)
  • Congestive heart failure is a chronic condition that is responsible for the highest number of hospitalizations among adults. (bartleby.com)
  • Introduction Congestive heart failure (CHF), also called chronic heart failure or congestive cardiac failure (CCF) is a clinical condition where heart muscle is weakened and cannot pump the blood as well as the normal heart. (bartleby.com)
  • The most likely causes of pediatric congestive heart failure depend on the age of the child. (medscape.com)
  • Congestive heart failure in the fetus, or hydrops , can be detected by performing fetal echocardiography. (medscape.com)
  • In this case, congestive heart failure may represent underlying anemia (eg, Rh sensitization, fetal-maternal transfusion), arrhythmias (usually supraventricular tachycardia), or myocardial dysfunction (myocarditis or cardiomyopathy). (medscape.com)
  • Curiously, structural heart disease is rarely a cause of congestive heart failure in the fetus, although it does occur. (medscape.com)
  • Neonates and infants younger than age 2 months are the most likely group to present with congestive heart failure related to structural heart disease. (medscape.com)
  • therefore, an increased suspicion of drug use is warranted in unexplained congestive heart failure. (medscape.com)
  • Although congestive heart failure in adolescents can be related to structural heart disease (including complications after surgical palliation or repair), it is usually associated with chronic arrhythmia or acquired heart disease, such as cardiomyopathy. (medscape.com)
  • For patient education information, see the Heart Health Center , as well as Congestive Heart Failure . (medscape.com)
  • Congestive heart failure occurs when the heart can no longer meet the metabolic demands of the body at normal physiologic venous pressures. (medscape.com)
  • As the demands on the heart outstrip the normal range of physiologic compensatory mechanisms, signs of congestive heart failure occur. (medscape.com)
  • Chest radiograph shows signs of congestive heart failure (CHF). (medscape.com)
  • Congestive heart failure is primarily caused by other conditions that damage the heart, such as diabetes , high blood pressure and coronary artery disease . (nationaljewish.org)
  • Other conditions that can cause congestive heart failure include heart muscle disease, heart valve disorders, and congenital heart defects. (nationaljewish.org)
  • Treatment for obstructive sleep apnea can help prevent congestive heart failure. (nationaljewish.org)
  • This "backing up" of fluid is sometimes referred to as "congestion" or congestive heart failure. (emoryhealthcare.org)
  • Congestive heart failure is a type of heart failure which requires seeking timely medical attention, although sometimes the two terms are used interchangeably. (heart.org)
  • Feline congestive heart failure is a condition that's caused by an abnormal structure of the heart, which makes it unable to pump blood throughout a cat's body. (vetinfo.com)
  • When a cat's has congestive heart failure, the walls of the heart thicken and the components of the organ are abnormally shaped. (vetinfo.com)
  • Stage D is when a cat is experiencing congestive heart failure and treatment is necessary. (vetinfo.com)
  • Congestive heart failure in a cat has a variety of different causes. (vetinfo.com)
  • A cat may be genetically predisposed to the condition or he could have be born with or acquire a heart problem that lead to congestive heart failure like, cardiomyopathy, arrhythmia, a diseased pericardium, congenital birth defects of the heart and degeneration of the heart valves. (vetinfo.com)
  • Parasites like heartworm can lead to congestive heart failure along with anemia, kidney failure, and a blood clot. (vetinfo.com)
  • Symptoms of congestive heart failure in a cat include difficulty breathing, shortness of breath, and a cough because of fluid that has built up in the lungs or chest cavity. (vetinfo.com)
  • If one suspects a cat to have congestive heart failure, a vet can run the following tests to confirm a diagnosis: physical exam and history, x-ray, ultrasound, electrocardiogram, and blood and urine tests. (vetinfo.com)
  • Medications often prescribed to a cat with congestive heart failure are diuretics, nitroglycerin, enzyme and ACE inhibitors, beta blockers, and calcium channel blockers. (vetinfo.com)
  • There is no cure for feline congestive heart failure. (vetinfo.com)
  • It's why some doctors call the disease congestive heart failure. (rexhealth.com)
  • Testosterone can ease shortness of breath and improve exercise endurance among patients with chronic heart failure , according to a combined analysis of four clinical trials. (go.com)
  • However, the pooled findings are from only 198 patients with chronic, stable heart failure , so they hardly provide the final word on treating the disorder with hormonal supplements, the study's lead author said. (go.com)
  • Heart failure is most often a long-term (chronic) condition, but it may come on suddenly. (medlineplus.gov)
  • ACC/AHA 2005 guideline update: chronic heart failure in the adult. (medicinenet.com)
  • His research interests include right heart failure, ventricular assist devices, symptom management in chronic heart failure. (ohsu.edu)
  • Patients with heart failure may need a provider at a moment's notice, when neither the primary provider nor cardiologist has capacity, making it essential to manage urgent and chronic concerns proactively. (ohsu.edu)
  • Naeije R. Pulmonary hypertension and right heart failure in chronic obstructive pulmonary disease. (springer.com)
  • However, only those patients with incident chronic heart failure (CHF) were more likely to have had follow-up HbA 1c tests than those free of CHF ( 2 ). (diabetesjournals.org)
  • Chronic heart failure (CHF) is the most common reason for hospital admissions in Germany. (aerzteblatt.de)
  • In August 2017, the German Medical Association (B K, Bundes- rzte-kammer ), the Federal Association of Statutory Health Insurers (KBV, Kassen rztliche Bundesvereinigung ), and the Association of Scientific Medical Societies in Germany (AWMF, Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften ) published a new, revised edition of the National Disease Management Guideline (NDMG, Nationale VersorgungsLeitlinie ) on chronic heart failure ( 2 ). (aerzteblatt.de)
  • The first edition of the Chronic Heart Failure NDMG was published in 2009 ( 8 ). (aerzteblatt.de)
  • Heart failure is usually a long-term (chronic) condition. (ipl.org)
  • Chronic Heart Failure is a condition where the heart has failed to support the physiological circulation needed to provide the organs and tissues of the body with nutrients and oxygen (Peate & Dutton 2012). (ipl.org)
  • NEW YORK (Reuters Health) - If you have chronic heart failure, being around a smoker may be bad for your physical and mental well-being, a new study suggests. (reuters.com)
  • Heart failure is a chronic condition in which the heart can no longer pump blood efficiently enough to meet the body's needs, which leads to symptoms like fatigue, breathlessness and swelling in the limbs. (reuters.com)
  • That's a significant difference, Fleischmann said -- akin to effects linked to certain chronic diseases, including heart failure itself. (reuters.com)
  • Supplements containing vitamins and other micronutrients can improve heart function and quality of life in elderly patients with chronic heart failure, claims a joint British-German study. (nutraingredients-usa.com)
  • THURSDAY, March 21, 2019 (HealthDay News) -- The Optimizer Smart System has been approved by the U.S. Food and Drug Administration for people with chronic, moderate-to-severe heart failure who are not candidates for other heart failure remedies. (hon.ch)
  • Patients with moderate-to-severe chronic heart failure have limited treatment options. (hon.ch)
  • However a new study has now cast doubt on the safety of the drug, following the deaths of ten chronic myelogenous leukaemia (CML) patients from heart failure while taking Gilvec. (netdoctor.co.uk)
  • The aim of this project is to investigate the sensitivity and selectivity of biosensor technology for the detection of biomarkers for chronic heart failure. (tue.nl)
  • In chronic heart failure, myocardial cells die from energy starvation, from cytotoxic mechanisms leading to necrosis, or from the acceleration of apoptosis or programmed cell death. (medscape.com)
  • 2016). 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. (roche.com)
  • Heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough blood through to meet the body's needs for blood and oxygen. (heart.org)
  • Doctors should not only treat the heart muscle in chronic heart failure patients, but also their leg muscles through exercise, say researchers in a major new study. (leeds.ac.uk)
  • In a series of experiments with chronic heart failure patients, the research team measured responses of the heart, lungs and leg muscles following a moderate exercise warm-up. (leeds.ac.uk)
  • Dr Harry Rossiter, of the University's Faculty of Biological Sciences says: 'Many chronic heart failure patients complain of leg fatigue during exercise and this can prevent them from being active. (leeds.ac.uk)
  • Dr Rossiter says the next stage of this research will be to see whether training of the skeletal muscles can improve long-term overall outcomes for patients with chronic heart failure, and to discover more about the pathological changes in the leg muscles that may be a contributing factor in limiting exercise. (leeds.ac.uk)
  • This study is published in the Journal of Applied Physiology in a paper entitled The intramuscular contribution to the slow oxygen uptake kinetics during exercise in chronic heart failure is related to the severity of the condition. (leeds.ac.uk)
  • Although it can be difficult living with a chronic condition like heart failure, people can continue to enjoy full lives as they address their symptoms. (ohsu.edu)
  • People with severe heart failure may need implanted devices (such as pacemakers, implantable cardiac defibrillators, or devices that help the heart pump blood) or surgery, including heart transplantation. (adam.com)
  • [5] Heart failure is not the same as myocardial infarction (in which part of the heart muscle dies) or cardiac arrest (in which blood flow stops altogether). (wikipedia.org)
  • Heart failure is a physiological state in which cardiac output is insufficient to meet the needs of the body and lungs. (wikipedia.org)
  • Gene Expression of Cardiac Myocytes: A Pharmacologic Target for the Failing Heart? (springer.com)
  • Cardiac muscle diseases such as amyloidosis or cardiomyopathy also damage the heart muscles and can lead to heart failure. (news-medical.net)
  • In heart failure, however, this mechanism fails due to weakened cardiac muscles which results in a failure of the heart to pump an adequate amount of blood. (news-medical.net)
  • To compensate for the lowered cardiac output, the heart rate rises. (news-medical.net)
  • In a healthy heart, increased filling of the ventricle results in increased contraction force (by the Frank-Starling law of the heart) and thus a rise in cardiac output. (wikipedia.org)
  • As the heart works harder to meet normal metabolic demands, the amount cardiac output can increase in times of increased oxygen demand (e.g., exercise) is reduced. (wikipedia.org)
  • This translates to the loss of one's cardiac reserve, or the ability of the heart to work harder during strenuous physical activity. (wikipedia.org)
  • citation needed] A common finding in those with heart failure is an increased heart rate, stimulated by increased sympathetic activity in order to maintain an adequate cardiac output. (wikipedia.org)
  • The general effect is one of reduced cardiac output and increased strain on the heart. (wikipedia.org)
  • This increases the risk of cardiac arrest (specifically due to abnormal ventricular heart rhythms) and reduces blood supply to the rest of the body. (wikipedia.org)
  • Binding to beta-1 receptors in the myocardium increases the heart rate and makes contractions more forceful in an attempt to increase cardiac output. (wikipedia.org)
  • An ICD is used for heart-failure treatment when the person is considered to be a high risk of dying from an abnormal heart rhythm -- called sudden cardiac death . (medicinenet.com)
  • Given that sudden cardiac death from fatal, abnormal heart rhythms causes about 50% of all heart-related deaths, ICDs have enormous potential. (medicinenet.com)
  • ICDs can be implanted alone, but they are also combined with other devices, such as cardiac resynchronization therapy, for heart failure treatment. (medicinenet.com)
  • The blood flow to her heart will become blocked and cardiac muscle cells will start to die off and get replaced with scar tissue. (nature.com)
  • In my opinion, patients with heart failure should definitely avoid secondhand smoke exposure -- both to minimize the risk of cardiac events such as heart attacks and because of the effects on health-related quality of life that we documented," Fleischmann told Reuters Health in an email. (reuters.com)
  • There is strong evidence that heart disease may be caused by vitamin D deficiency, according to researchers from the University of Bonn in Germany, who have been studying the causes of cardiac failure. (nutraingredients-usa.com)
  • Included are some easy-to-understand brochures about cardiac devices and the heart conditions they are designed to treat, as well as information about electromagnetic compatibility. (medtronic.com)
  • You may be eligible for an implantable heart device called cardiac resynchronisation therapy (CRT). (medtronic.com)
  • Along with your child's heart doctor (cardiologist), you are connected with other providers, such as cardiac intensivists , newborn specialists (neonatologists), neurodevelopmental pediatricians, nurses, child life specialists , social workers and others, if their expertise is needed. (seattlechildrens.org)
  • Participants were either New York Heart Association (NYHA) functional class III (cardiac disease resulting in marked limitation of physical activity) or ambulatory functional Class IV (cardiac disease resulting in inability to carry on any physical activity without discomfort). (livescience.com)
  • Some cases of heart failure are not accompanied by symptoms of congestion, but by low cardiac output, which can present itself as excessive fatigue and physical weakness. (wikihow.com)
  • Low cardiac output means that the heart cannot pump enough blood to meet the needs of all your body tissues. (wikihow.com)
  • Candidates for the system should have a regular heart rhythm, not be eligible for cardiac resynchronization therapy and have a left ventricular ejection fraction (the total amount of blood pumped out in each heartbeat) of 25 to 45 percent, which is below the normal ejection fraction of 55 to 75 percent. (hon.ch)
  • Although edematous patients with heart failure have increased plasma and extracellular fluid volumes, the body perceives volume depletion (reduced effective arterial blood volume) since the low cardiac output decreases the pressure perfusing the baroreceptors in the carotid sinus and the renal afferent arteriole. (uptodate.com)
  • Studies have shown NT-proBNP measurements to be useful in the diagnosis of heart failure and risk stratification of patients with different cardiac pathologies, e.g. patients with possible complications are characterised by significantly higher NT-proBNP levels. (tue.nl)
  • The report is published in the February issue of Journal of Cardiac Failure . (psychcentral.com)
  • This is a very important article dealing with a neglected area of research," commented Barry M. Massie, M.D., Editor-in-Chief of the Journal of Cardiac Failure . (psychcentral.com)
  • Heart rate and stroke volume produce cardiac output. (bartleby.com)
  • Heart failure develops when the heart, via an abnormality of cardiac function (detectable or not), fails to pump blood at a rate commensurate with the requirements of the metabolizing tissues or is able to do so only with an elevated diastolic filling pressure. (medscape.com)
  • This chest radiograph shows an enlarged cardiac silhouette and edema at the lung bases, signs of acute heart failure. (medscape.com)
  • Heart failure (see the images below) may be caused by myocardial failure but may also occur in the presence of near-normal cardiac function under conditions of high demand. (medscape.com)
  • For example, in patients with suspected symptoms of heart failure, NT-proBNP, which is released in the blood, can help to distinguish cardiac causes from non-cardiac causes, such as of shortness of breath and other symptoms. (roche.com)
  • Progressive cardiac remodeling is the main predictor of heart failure development. (ahajournals.org)
  • Despite extensive research and advances in drug development, there is still a strong need for novel pharmacological agents that attenuate cardiac remodeling and prevent heart failure. (ahajournals.org)
  • Our results identify galectin-3 as a feasible target for therapy to prevent cardiac remodeling and heart failure. (ahajournals.org)
  • The program also has earned the American Heart Association's " Target: Heart Failure Gold Plus " award, and the heart-failure care team was honored with the Beacon Award for Nursing Excellence in acute cardiac patient care. (smh.com)
  • Heart failure can develop slowly over time as the result of other conditions (such as high blood pressure and coronary artery disease) that weaken the heart. (adam.com)
  • Common causes of heart failure include coronary artery disease including a previous myocardial infarction (heart attack), high blood pressure , atrial fibrillation , valvular heart disease , excess alcohol use , infection , and cardiomyopathy of an unknown cause. (wikipedia.org)
  • Heart failure can be caused by coronary artery disease, heart attack, cardiomyopathy, and high blood pressure. (webmd.com)
  • In otherwords, the earlier data revealed only the part of the case load.A lot of effort is invested on methods which detect risk factors, disease of the coronary (heart)arteries, abnormal heart muscle functioning, all at a very early stage and in a non-invasivemanner. (slideshare.net)
  • Coronary artery disease (CAD), a narrowing or blockage of the small blood vessels that supply blood and oxygen to the heart. (medlineplus.gov)
  • The most common cause of heart failure is coronary artery disease (CAD), a disorder that causes narrowing of the arteries that supply blood and oxygen to the heart. (yahoo.com)
  • Certain conditions, such as narrowed arteries in your heart (coronary artery disease ) or high blood pressure, gradually leave your heart too weak or stiff to fill and pump efficiently. (yahoo.com)
  • Initially, this helps compensate for heart failure by maintaining blood pressure and perfusion, but places further strain on the myocardium, increasing coronary perfusion requirements, which can lead to worsening of ischemic heart disease. (wikipedia.org)
  • Revascularization is frequently advocated to improve ventricular function and prognosis for patients with heart failure due to coronary artery disease, especially when there is evidence of extensive myocardial viability. (nih.gov)
  • A conservative management strategy may not be inferior to one of coronary arteriography with the intent to revascularize in patients with heart failure, LV systolic dysfunction, and extensive myocardial viability. (nih.gov)
  • Heart failure is often a complication of other conditions related to heart health, including coronary heart disease, high blood pressure and diabetes. (healthday.com)
  • specific tests that are used to evaluate the heart function and/or structure, such as echocardiograms (ultrasound of the heart), stress tests, exercise tests, or coronary angiograms. (emoryhealthcare.org)
  • primary disease of the heart muscle itself, called cardiomyopathy. (archive.org)
  • The heart isn't pumping normally (for example, from a congenital heart defect or cardiomyopathy ). (kidshealth.org)
  • The poor prognosis of these patients has been explained by an underlying diabetic cardiomyopathy exacerbated by hypertension and ischemic heart disease. (diabetesjournals.org)
  • New research will help doctors identify, treat and prevent potentially dangerous irregular heartbeats in patients with hypertrophic cardiomyopathy (HCM), a common heart condition in which the heart thickens and strains to pump blood. (news-medical.net)
  • Cardiomyopathy , a name for any disease of the heart muscle, is one condition that often leads to heart failure. (hopkinsmedicine.org)
  • Our Heart Failure Program provides coordinated and comprehensive care for more than 350 patients each year with cardiomyopathy and other types of heart failure . (seattlechildrens.org)
  • It's important to note that both of these can also be complications of heart failure that can lead to cardiomyopathy, heart attacks, and strokes. (wikihow.com)
  • Cardiomyopathy, or heart muscle disease, is a major cause of heart failure. (intermountainhealthcare.org)
  • Our team has special expertise in treating women with peripartum cardiomyopathy - a rare form of heart failure that occurs in the late stages of pregnancy, during delivery, or shortly afterwards. (intermountainhealthcare.org)
  • heart failure due to left ventricular dysfunction and heart failure with normal ejection fraction depending on whether the ability of the left ventricle to contract is affected, or the heart's ability to relax. (wikipedia.org)
  • The two types of left ventricular heart failure - heart failure with reduced ejection fraction (HFrEF), and heart failure with preserved ejection fraction (HFpEF) - are based on whether the ability of the left ventricle to contract, or to relax, is affected. (wikipedia.org)
  • At hospital discharge, Medical Center cardiology patients with Stage B or C heart failure and/or with an ejection fraction of less than 40 percent are frequently scheduled for follow-up appointments at the clinic in an effort to reduce their future ED visits and readmissions. (rwjf.org)
  • This is called systolic heart failure, or heart failure with a reduced ejection fraction (HFrEF). (medlineplus.gov)
  • This is called diastolic heart failure, or heart failure with a preserved ejection fraction (HFpEF). (medlineplus.gov)
  • Approximately half of people with heart failure have preserved ejection fraction, while the other half have a reduction in ejection fraction, called heart failure with reduced ejection fraction (HFrEF). (wikipedia.org)
  • This is a rigorously validated and well-documented semi-supervised deep learning Solution for phenotyping patients with heart failure with preserved ejection fraction (HFpEF). (nih.gov)
  • Successful application of advanced machine learning approaches for identifying factors leading to differential treatment effects in heart failure with preserved ejection fraction (HFpEF) could be crucial in generating hypotheses regarding the role of certain etiologic factors in putative treatment benefits. (nih.gov)
  • Learn about ejection fraction heart failure measurement . (heart.org)
  • See 'Predictors of survival in heart failure with reduced ejection fraction', section on 'Neurohumoral activation and heart rate' . (uptodate.com)
  • Diastolic heart failure is also known as heart failure with preserved systolic function or heart failure with normal ejection fraction. (bartleby.com)
  • If your ejection fraction gets lower and you are having more symptoms, it means that your heart failure is getting worse. (rexhealth.com)
  • [18] A ventricular assist device or occasionally a heart transplant may be recommended in those with severe disease despite all other measures. (wikipedia.org)
  • A heart transplant could be an option. (archive.org)
  • In recent years, though, it has had some of the worst heart transplant outcomes in the country. (propublica.org)
  • The sudden removal of the three executives follows a yearlong investigation by ProPublica and the Houston Chronicle into widespread problems at the hospital, including deaths in its heart transplant program. (propublica.org)
  • Defibrillator paddles did not work during a patient's heart transplant in January, and a backup set was not nearby. (propublica.org)
  • The hiring of two outside surgeons comes after Medicare terminated funding to the heart transplant program, citing poor outcomes in recent years. (propublica.org)
  • At present, the best treatment for heart failure is a heart transplant. (medicalnewstoday.com)
  • However, the number of heart failure patients far exceeds the number of hearts available for transplant. (medicalnewstoday.com)
  • Dr. Mudd is the medical director of the Heart Failure and Transplant program at the OHSU Knight Cardiovascular Institute. (ohsu.edu)
  • This surgically implanted heart pump supports patients awaiting transplant or non-transplant candidates. (ohsu.edu)
  • Heart transplant is another option for appropriate patients, and OHSU is home to Oregon's only heart transplant program. (ohsu.edu)
  • Some stem from the familiar pacemaker, others from devices designed as a stopgap before heart transplant . (medicinenet.com)
  • Learn more about our heart transplant program. (childrens.com)
  • If the heart failure is serious and irreversible, heart transplant surgery may be considered. (medtronic.com)
  • Though LVADs are typically only installed to keep patients functioning as they wait for a heart transplant, Cheney, who has survived five heart attacks, did not say whether he plans to take that step. (foxnews.com)
  • That's not as good as a heart transplant, which offers a survival rate of about 70% after 10 years. (wsj.com)
  • Our Heart Transplant Program has performed more than 700 transplants and is the only one in Oregon approved by the United Network for Organ Sharing and the Centers for Medicare & Medicaid Services. (ohsu.edu)
  • Dr. Deborah Meyers is the Section Head for Heart Failure and Transplant Cardiology at OHSU. (ohsu.edu)
  • As Oregon's only research and teaching hospital, OHSU provides all types of heart failure and transplant care, including the most complex. (ohsu.edu)
  • Watch how OHSU's multidisciplinary heart team is helping Wesley stay healthy and active while he waits for his heart transplant. (ohsu.edu)
  • These data are interesting," said Dr. Clyde W. Yancy , cardiology chief at Northwestern University in Chicago and a former American Heart Association president. (go.com)
  • Revised American College of Cardiology/American Heart Association guidelines for the management of heart failure. (medicinenet.com)
  • The American College of Cardiology Foundation and American Heart Association released new heart failure management guidelines in 2013, published in Circulation . (ohsu.edu)
  • A recent study published in the Journal of the American College of Cardiology found that Abbott's sensor reduced hospitalizations due to heart failure by 46 percent and cut patient medical costs by $7,000 over the following six months. (washingtonexaminer.com)
  • Bikdeli's report is an indication of the lack of proper "head-to-head studies" of different heart failure treatments, said cardiology professor Harlan Krumholz, who also worked on the research. (yaledailynews.com)
  • SANTA MONICA, Calif. , Oct. 28, 2013 /PRNewswire/ -- Leonhardt Ventures will showcase its cardiovascular and heart disease related technologies Tuesday, October 29th, 3pm to 4pm @ PARISOMA 169 11th Street, San Francisco, CA 94103 - Conveniently located walking distance or short taxi (9 blocks) from the Moscone Center where the TCT Cardiology Conference is taking place. (prnewswire.com)
  • Cite this: Heart Failure: the Year in Cardiology 2019 - Medscape - Mar 21, 2020. (medscape.com)
  • A lot of the big advances that we've had in treating heart failure in the last few years has been with devices," says Marvin A. Konstam, MD, chief of cardiology and director of cardiovascular development at Tufts-New England Medical Center. (medicinenet.com)
  • Usefulness of myeloperoxidase levels in healthy elderly subjects to predict risk of developing heart failure," American Journal of Cardiology , vol. 103, no. 9, pp. 1269-1274, 2009. (hindawi.com)
  • Hospitalizations for new heart failure among subjects with diabetes mellitus in the RENAAL and LIFE studies," American Journal of Cardiology , vol. 96, no. 11, pp. 1530-1536, 2005. (hindawi.com)
  • Prediction of incident heart failure in the elderly: validation of the health abc hf model in the cardiovascular health study," in Proceedings of the 58th Annual Scientific Session of the American-College-of-Cardiology , p. (hindawi.com)
  • U.S. News & World Report consistently ranks Seattle Children's cardiology and heart surgery program among the best in the country. (seattlechildrens.org)
  • we expect that the link persists beyond one year," said Cleland at the annual meeting of the Heart Failure Association of the European Society of Cardiology in May in Seville, Spain. (psychcentral.com)
  • 2013). 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. (roche.com)
  • Led by Medical Director Michael Mumma, MD, the Heart Failure Care team includes more than 50 cardiology specialists, as well as highly trained cardiovascular nurse specialists for inpatient care. (smh.com)
  • To understand what occurs in heart failure, it helps to understand the anatomy of the heart and how it works. (adam.com)
  • So, the team silenced the Hippo pathway in a mouse model that mimics the type of advanced heart failure that occurs in humans after a heart attack. (medicalnewstoday.com)
  • That enables doctors to anticipate heart problems early and adjust treatments before a health crisis occurs. (washingtonexaminer.com)
  • One of the biggest differences is that heart disease happens gradually over time while a heart attack occurs suddenly and is an emergency. (yahoo.com)
  • Heart failure occurs when the muscles of the heart become weak and have difficulty pumping enough blood to nourish your body's many cells. (yahoo.com)
  • Learn what happens before, during and after a heart attack occurs. (medhelp.org)
  • Heart failure is a condition that occurs when the heart becomes weak and does not pump blood efficiently. (ipl.org)
  • Systolic and Diastolic Heart Failure Heart failure occurs when the heart cannot pump enough blood for the body due to a weakened or damaged heart. (ipl.org)
  • This condition usually occurs because the muscles of the heart have weakened or are too stiff to work. (ipl.org)
  • B-type natriuretic peptide (BNP) is a hormone released from the ventricles in response to increased wall tension (stress) that occurs with heart failure. (hopkinsmedicine.org)
  • Heart failure occurs when the heart muscles can't pump enough blood to meet the body's need for blood and oxygen. (livescience.com)
  • Edema occurs because your heart is not able to pump your blood forward, resulting in blood backing up in the systemic veins (the veins that carry blood from our whole body to the right side of the heart). (wikihow.com)
  • Exacerbation usually occurs when a change in your body places increased demand on your already weakened heart, which can't compensate to meet the demand by beating harder or faster. (wikihow.com)
  • Some 5.7 million people in the United States have heart failure, which occurs when the heart cannot pump enough blood. (hon.ch)
  • Heart failure occurs when your heart is no longer meeting the blood-pumping needs of your body. (healthday.com)
  • It's a condition that typically occurs gradually over time as the heart weakens. (healthday.com)
  • ﻽Systolic heart failure occurs when the heart does not squeeze as well as it should, due to a weakened heart muscle. (emoryhealthcare.org)
  • Diastolic heart failure occurs when the heart squeezes well but cannot properly fill with blood because the muscle has thickened and has lost its ability to relax. (emoryhealthcare.org)
  • The increase in muscle mass occurs because the contracting cells of the heart get bigger. (heart.org)
  • In about half of cases, LVH occurs without other evidence of heart damage or stress, and in these cases the prognosis appears to be benign and similar to people without LVH. (eurekalert.org)
  • In contrast, in the other half of cases, when LVH occurs together with signs of damage or stress to the heart muscle, the course is malignant and associated with a markedly higher risk of heart failure. (eurekalert.org)
  • Researchers at University of Utah Health and VA Salt Lake City Health Care System say the new device, worn as a patch, uses artificial intelligence to help doctors detect critical changes in heart failure patients days before an actual heart-related emergency, like a heart attack, occurs. (upi.com)
  • The oxygen-rich blood returns through veins coming from the lungs (pulmonary veins) to the heart. (adam.com)
  • The heart receives the oxygen-rich blood from the lungs in the left atrium , the first chamber on the left side. (adam.com)
  • When a person has heart failure, the heart cannot pump strongly enough to supply blood to the body, allowing fluids to build up in the lungs, arms and legs. (go.com)
  • A weak heart causes fluid to back up in the lungs. (webmd.com)
  • The left side of the heart receives oxygen-rich blood from the lungs and pumps it forward to the systemic circulation (the rest of the body except for the pulmonary circulation). (wikipedia.org)
  • Failure of the left side of the heart causes blood to back up (be congested) into the lungs, causing respiratory symptoms and fatigue due to insufficient supply of oxygenated blood. (wikipedia.org)
  • the aorta originates from the right ventricle, so most of the blood returning to the heart from the body is pumped back out without first going to the lungs. (slideshare.net)
  • This can be referred to as ' right-sided heart failure ' as failure of the right-sided heart chambers to pump venous blood to the lungs to acquire oxygen results in buildup of this fluid in gravity-dependent areas such as in the legs. (medicinenet.com)
  • If blood backs up in the heart, there's no room for the blood that's returning from the body and lungs. (kidshealth.org)
  • For some people with heart failure, fluid may back up into the lungs and there may be swelling (edema) in the lower legs. (ipl.org)
  • The heart 's pumping action moves oxygen-rich blood as it travels from the lungs to the left atrium, then on to the left ventricle, which pumps it to the rest of the body. (ipl.org)
  • When the left ventricle of your heart is not able to pump the blood forward, blood "backs up" in the pulmonary veins (the vessels that return blood from the lungs to the heart after oxygenation). (wikihow.com)
  • With systolic and/or diastolic heart failure, blood can "back up" into your lungs and other parts of your body such as your hands, abdomen (belly), legs, and feet. (emoryhealthcare.org)
  • The heart pumps blood to the lungs and to all the body's tissues by a sequence of highly organized contractions of the four chambers. (heart.org)
  • Blood then backs up in the veins and lungs, thus making the heart weaker. (vetinfo.com)
  • As heart failure gets worse, fluid starts to build up in your lungs and other parts of your body. (rexhealth.com)
  • Authors are encouraged to submit reviews in the field of Heart Failure on the topics of clinical and surgical approaches to therapy, basic pharmacology, biochemistry, molecular biology, pathology, and electrophysiology. (springer.com)
  • Heart Failure Reviews is an international journal which develops links between basic scientists and clinical investigators, creating a unique, interdisciplinary dialogue focused on heart failure, its pathogenesis and treatment. (springer.com)
  • This really goes beyond the beta blocker and heart failure story, it's about how we conduct clinical trials,' he said. (ibtimes.com)
  • Right ventricular function in cardiovascular disease, part II: pathophysiology, clinical importance, and management of right ventricular failure. (springer.com)
  • The clinical diagnosis of heart failure can be challenging as signs and symptoms may be non-specific. (bmj.com)
  • 1 In the United Kingdom the 2010 guidelines from the National Institute for Health and Clinical Excellence (NICE) recommend that when heart failure is suspected, the initial investigations listed below are useful in primary care. (bmj.com)
  • Diabetic subjects make up ∼25% of all patients enrolled in large-scale clinical trials evaluating treatments for HF: 23% in the Cooperative North Scandinavian Enalapril Survival Study, 25% in SOLVD (Studies of Left Ventricular Dysfunction), 20% in the Vasodilation Heart Failure Trial II, 20% in ATLAS (Assessment of Treatment with Lisinopril and Survival), and 27% in RESOLVD (Randomized Evaluation for Strategies of Left Ventricular Dysfunction) ( 8 - 12 ). (diabetesjournals.org)
  • Cardiobridge - http://www.cardiobridge.com - Highest flow rate 10FR circulatory support catheter pump in clinical testing for acute decompensating heart failure and high-risk PCI. (prnewswire.com)
  • In accordance with recent calls to improve data sharing, the Solution will be reusable and will support the creation of virtual cohorts and extraction of datasets from acute heart failure clinical studies. (nih.gov)
  • Sex differences in clinical characteristics and prognosis in a broad spectrum of patients with heart failure-results of the Candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) program," Circulation , vol. 115, no. 24, pp. 3111-3120, 2007. (hindawi.com)
  • CRT has proven clinical efficacy in managing individuals with heart failure. (medtronic.com)
  • Dr. William Abraham , director of the Division of Cardiovascular Medicine at The Ohio State University Wexner Medical Center , and lead investigator in a clinical trial funded by Sunshine Heart, contributed this article to Live Science's Expert Voices: Op-Ed & Insights . (livescience.com)
  • Now, results from a feasibility clinical trial show that a new investigational medical device made by Sunshine Heart can reduce the work needed to pump blood throughout the body and improve the quality of life for patients with advanced heart failure. (livescience.com)
  • The device was evaluated in clinical studies involving 389 people with moderate-to-severe heart failure. (hon.ch)
  • Following the initial U.S. clinical experience with metformin, postmarketing surveys indicated that reported cases of lactic acidosis frequently involved patients with heart failure ( 10 ). (diabetesjournals.org)
  • Researchers say the drug tafamidis has shown in clinical trials that it can lessen the effects of a heart condition known as ATTR-CM. (healthline.com)
  • Having a full clinical picture, with the right objective information, allows physicians to make the best decisions in heart failure management to benefit patients. (roche.com)
  • This observational study will be a significant step towards understanding how repeated measurements of blood volume and kidney function can change clinical decision making and ultimately improve management of heart failure patients. (prnewswire.com)
  • On contemporary immunosuppression, two thirds of patients reach a partial clinical remission characterized by freedom from severe heart failure and need of transplantation. (ahajournals.org)
  • Summary -Relief of dyspnea constitutes a major treatment goal in acute heart failure and an important end point in clinical trials. (ahajournals.org)
  • These results suggest that the failure to achieve early dyspnea relief in clinical practice and in clinical trials is likely related, at least in part, to the failure to achieve a rapid reduction in these hemodynamic parameters. (ahajournals.org)
  • Clinical resources for health care professionals to improve the management of patients with heart failure. (heartfoundation.org.au)
  • The researchers plan to conduct a large clinical trial that will use the system to alert doctors of changes in a patient's condition, as well as track if early intervention based on these alerts leads to fewer re-hospitalizations for heart failure. (upi.com)
  • The LGI is home to the Yorkshire Heart Centre, which treats patients from across West Yorkshire, North Yorkshire and beyond and has an excellent clinical and research reputation. (leeds.ac.uk)
  • One example is heart muscle damage caused by a heart attack or myocardial infarction. (news-medical.net)
  • In myocardial infarction, there is a lack of blood supplied to the heart muscles causing them to be starved of oxygen and leading to death of the muscle tissue. (news-medical.net)
  • Its incidence is continuing to rise, partly owing to demographic developments and partly to improved survival after myocardial infarction and other forms of heart disease. (aerzteblatt.de)
  • previous heart attack (s) (myocardial infarction) - scar tissue from prior damage may interfere with the heart muscle's ability to pump normally (most common cause in the U.S. (hopkinsmedicine.org)
  • [6] In those with heart failure due to left ventricular dysfunction, angiotensin converting enzyme inhibitors or angiotensin receptor blockers along with beta blockers are recommended. (wikipedia.org)
  • Myocardial dysfunction, pressure overload, volume overload, and preload reduction are the main mechanisms of right heart failure. (springer.com)
  • Ghio S, Tavazzi L. Right ventricular dysfunction in advanced heart failure. (springer.com)
  • The dysfunction can occur in the left chambers of the heart or the chambers on the right or even both. (ipl.org)
  • Patients with heart failure often have coexisting renal dysfunction. (diabetesjournals.org)
  • In systolic ventricular dysfunction or systolic heart failure the heart is not able to produce enough output for adequate tissue perfusion. (bartleby.com)
  • Ventricular remodeling causes hypertrophy and dilation of the heart muscle and causes progressive myocyte contractile dysfunction over a period of time. (bartleby.com)
  • The University of Leeds research team has, for the first time, shown that leg muscle dysfunction is related to the severity of symptoms in heart failure patients. (leeds.ac.uk)
  • Heart failure is a major human disease that afflicts millions of people worldwide. (keystonesymposia.org)
  • [14] [15] Other diseases that may have symptoms similar to heart failure include obesity , kidney failure , liver problems, anemia , and thyroid disease . (wikipedia.org)
  • And, testosterone supplementation has been associated with better cholesterol levels among men with heart disease, Ezekowitz and his colleagues noted in their study. (go.com)
  • Abuse of testosterone, a steroid hormone that helps athletes and bodybuilders bulk up, has been associated with cardiovascular disease, increased risk of heart attack, and mood changes, as well as prostate cancer. (go.com)
  • Can Antioxidant Supplements Prevent Heart Disease? (webmd.com)
  • Find out what they revealed about antioxidants and heart disease. (webmd.com)
  • Since 2011, Grady Memorial Hospital, a public safety net hospital in Atlanta, Georgia, has offered the Grady Heart Failure Program as a way to decrease health disparities in cardiovascular disease (CVD) care for vulnerable patients. (cdc.gov)
  • The program identifies and enrolls heart failure patients, provides inpatient and is associated with poor outpatient services, and offers services to reduce socioeconomic challenges to care and cardiovascular disease management of patients' CVD conditions. (cdc.gov)
  • An off-site, nurse-led heart failure clinic was created to help heart failure patients better control and self-manage their disease post-hospitalization. (rwjf.org)
  • From all indications, the clinic is helping our patients better self-manage their heart disease and better transition from the hospital to the ambulatory setting so that they don't need to return to the emergency department or be readmitted. (rwjf.org)
  • Heart failure is the No. 1 reason for hospitalization among adults in Mississippi, largely because they are neither receiving the care they need in an ambulatory or outpatient setting nor managing their disease with diet, exercise and lifestyle changes. (rwjf.org)
  • Right-sided heart failure can also be caused by severe lung disease (referred to as 'cor pulmonale'), or by intrinsic disease of the right heart muscle (less common). (medicinenet.com)
  • Hypertension , obesity , metabolic syndrome , and sedentary lifestyle have been identified as important risk factors for diverse types of heart disease including HFpEF. (wikipedia.org)
  • Heart failure remains the leading cause of mortality from heart disease ," explains corresponding author James F. Martin, a professor who specializes in regenerative medicine at Baylor College of Medicine and who is also director of the Cardiomyocyte Renewal Lab at the Texas Heart Institute, also in Houston. (medicalnewstoday.com)
  • The heart failure team at OHSU Knight Cardiovascular Institute, which recently earned Joint Commission Advanced Certification in Heart Failure, offers suggestions to reduce morbidity, improve quality of life, and potentially slow disease progression. (ohsu.edu)
  • Women with cardiovascular disease may present with different symptoms than men, so heart failure may be unrecognized. (ohsu.edu)
  • Heart failure is a progressive condition, and at some point, the disease and symptoms progress despite medications. (ohsu.edu)
  • What is the difference between heart disease and heart failure? (yahoo.com)
  • Heart failure is most often related to another disease or illness. (yahoo.com)
  • What is the disease process of heart failure? (yahoo.com)
  • What is heart failure disease? (yahoo.com)
  • Heart Disease an Issue? (healthcentral.com)
  • Since 1982 Leonhardt Ventures has a strong history of inventing, developing, backing and bringing to market leadership products for treating heart and cardiovascular disease. (prnewswire.com)
  • Even so, the findings add to a growing body of evidence linking sodas and other sweetened beverages to heart disease, they wrote. (reuters.com)
  • This machine learning-based semi-supervised sub-phenotyping schema incorporates multiple disease-related factors among patients with acute decompensated heart failure (ADHF) to derive three phenogroups according to their diuretic efficiency. (nih.gov)
  • The prognosis of cardiovascular disease is determined to a large extent by the ability to delay or prevent the development and progression of heart failure. (medscape.com)
  • Implantable devices have been used for decades to treat heart disease . (medicinenet.com)
  • Given that heart failure is not a specific disease in itself, but rather a condition that results from other illnesses, different approaches have been developed to treat the condition. (medicinenet.com)
  • Heart disease and stroke statistics-2009 update: a report from the American heart association statistics committee and stroke statistics subcommittee," Circulation , vol. 119, no. 3, pp. e21-e181, 2009. (hindawi.com)
  • Heart Disease and Saturated Fat: Do the Dietary Guidelines Have It All Wrong? (medhelp.org)
  • Can Mental Stress Lead to Heart Disease? (medhelp.org)
  • Can depression and anxiety cause heart disease? (medhelp.org)
  • All patients with heart failure are suggested to be enrolled in a structured program (e.g., a disease management program) including coordinated multidisciplinary care and continuous educational interventions. (aerzteblatt.de)
  • But they add to the large body of evidence tying secondhand smoke to heart disease, researchers say. (reuters.com)
  • A number of studies have found that non-smokers who regularly breathe in other people's tobacco smoke have an increased risk of developing heart disease. (reuters.com)
  • So are changes in our microbiome causing heart disease, or visa-versa? (nutraingredients-usa.com)
  • Our Interactive Cardiovascular Library has detailed animations and illustrations to help you learn about conditions, treatments and procedures related to heart disease and stroke. (heart.org)
  • If your child's heart failure is caused by complex congenital heart disease, they may be at risk for problems with the growth and development of their brain and central nervous system. (seattlechildrens.org)
  • More than 5 million people in the United States have heart failure, one of the fastest-growing forms of heart disease in the nation. (livescience.com)
  • Heart failure (HF) is characterized by the elaboration of a portfolio of pro-inflammatory cytokines and inflammatory mediators that are considered to contribute to disease progression by virtue of the deleterious effects that these molecules exert on the heart and circulation. (nih.gov)
  • Patients whose serum sodium levels fall below 125 meq/L solely as a result of heart failure usually have near end-stage disease. (uptodate.com)
  • Changes in cognitive function have long been recognized in patients with heart disease. (psychcentral.com)
  • It's a rare disease in which certain proteins gradually build up in the tissues of the heart, eventually making it more difficult for the heart to pump blood to the rest of the body. (healthline.com)
  • With this disease, a protein called transthyretin unravels, travels to the heart, and clumps together there in deposits. (healthline.com)
  • In the longer term, at the cardiologist's office, or general practitioner, this testing helps physicians to monitor the disease progression and work on the long term management of heart failure. (roche.com)
  • 9,10 Therefore, current guidelines recommend such tests to aid in the diagnosis, to assess the disease severity and get prognostic information all along the heart failure patient journey. (roche.com)
  • For all the scares about cancer, heart disease is still the number-one killer disease in the West. (healthy.net)
  • This disease of the heart muscle, often caused by a heart attack, is one of the UK's leading causes of disability. (bbc.co.uk)
  • Together, we can make heart disease history. (heartfoundation.org.au)
  • There are four stages of cat heart disease: A, B, C and D. In stage A, a cat has heart disease, but doesn't have any symptoms. (vetinfo.com)
  • Stage B is when heart disease is present, but there aren't any occurring symptoms. (vetinfo.com)
  • In stage C, heart disease symptoms have manifested themselves. (vetinfo.com)
  • Disease of the sac around the heart (pericardial disease), such as pericarditis. (rexhealth.com)
  • If the heart failure is caused by an abnormal heart valve, the valve can be surgically replaced. (archive.org)
  • They may retain fluid, be unable to exercise, or have an abnormal heart beat. (washingtonexaminer.com)
  • Sympathetic activity may also cause potentially fatal abnormal heart rhythms. (wikipedia.org)
  • If the ICD senses a dangerous abnormal heart rhythm, it delivers an internal electric shock to the heart -- the equivalent of being shocked with paddles outside the body -- that hopefully restores a normal heart rhythm. (medicinenet.com)
  • This is particularly troublesome in people who have frequent episodes of this potentially fatal abnormal heart rhythm. (medicinenet.com)
  • The Seattle Heart Failure Model (SHFM) is a calculator of projected survival at baseline and after interventions for patients with heart failure. (washington.edu)
  • Around half of patients with heart failure do not live more than 5 years after diagnosis. (medicalnewstoday.com)
  • In their study paper , he and his colleagues explain that the Hippo pathway - "a kinase cascade that prevents adult cardiomyocyte proliferation and regeneration" - is more active in patients with heart failure. (medicalnewstoday.com)
  • In general, patients with heart failure benefit from ACE inhibitors or angiotensin receptor blockers and beta blockers. (ohsu.edu)
  • If renal function worsens, it may seem appropriate to stop the ACE inhibitor or ARB, but patients with heart failure should take a vasodilator and substituting hydralazine and nitrates for afterload reduction is important. (ohsu.edu)
  • Patients with heart failure have a predictably unpredictable condition, but a systems approach can decrease the number of emergency calls and visits as well as morbidity. (ohsu.edu)
  • Research shows that patients with heart failure struggle to keep doctor's appointments, don't feel comfortable with their physicians, and often suffer from neurological problems like confusion or short-term memory loss. (washingtonexaminer.com)
  • In some patients with heart failure, the electrical signals that coordinate pumping of the different heart chambers become erratic, making the heart unable to pump blood efficiently. (medicinenet.com)
  • A daily supplement of omega-3 polyunsaturated fatty acids may reduce mortality and admission to hospital for cardiovascular reasons in patients with heart failure, says a new study. (nutraingredients-usa.com)
  • Patients with heart failure who have this severity of hyponatremia also frequently have hyperkalemia. (uptodate.com)
  • The concentration of NT-proBNP in blood plasma can increase from picograms/ml for healthy adults to several tens of nanograms/ml for patients with heart failure. (tue.nl)
  • Patients with heart failure are at high risk of recurrent hospital admissions and death," said researcher Professor John Cleland of Imperial College London, UK. (psychcentral.com)
  • Depression has been reported to predict death in patients with heart failure but until now it was thought that this could be because depressed patients have more severe heart failure and more comorbidities. (psychcentral.com)
  • This is because studies suggest they are not effective in reducing depression in patients with heart failure," Cleland said. (psychcentral.com)
  • Clinicians should, however, screen patients with heart failure for depression and consider referring those affected for counseling," he added. (psychcentral.com)
  • Recognition and management of depression may reduce mortality for patients with heart failure," he concluded. (psychcentral.com)
  • Therefore, depression reduces the commitment of patients to medication regimes and it is not surprising if depressed patients with heart failure have no commitment to therapeutic recommendations such as diet modification and lifestyle changes such as exercise and physical activity, smoking cessation, and participation in rehabilitation and educational programs. (psychcentral.com)
  • Nearly half of patients with heart failure (HF) have problems with memory and other aspects of cognitive functioning, reports a new study. (psychcentral.com)
  • We have developed these resources are to help educate your patients with heart failure about their condition, how to recognise signs and symptoms, information about medications and things that can make them feel better. (heartfoundation.org.au)
  • But what does that mean for our patients with heart failure? (smh.com)
  • Feb. 25 (UPI) -- A wearable sensor may be able to detect -- and thus prevent -- a major health emergency in patients with heart failure, according to a study published Tuesday in the journal Circulation: Heart Failure . (upi.com)
  • Our main message is that exercise is safe and beneficial in patients with heart failure. (leeds.ac.uk)
  • OHSU's Heart Failure team treats patients with heart failure using the most innovative therapies and compassionate, patient-centered approach. (ohsu.edu)
  • This observation appears puzzling as it implies that the increased risk of ACS in patients in Group C did not lead to an increased risk of death due to pump failure or arrhythmia, as might be expected. (medscape.com)
  • You may experience a rapid heartbeat (tachycardia) or an irregular heartbeat (arrhythmia) as symptoms of heart failure. (wikihow.com)
  • A slow, fast, or uneven heart rhythm (arrhythmia). (rexhealth.com)
  • Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this complex problem, involving cardiomyopathic processes and ischemia perfusion injury. (springer.com)
  • Retrieved on December 03, 2020 from https://www.news-medical.net/health/Heart-Failure-Pathophysiology.aspx. (news-medical.net)
  • Pathophysiology of right ventricular failure. (springer.com)
  • Pathophysiology and management of right heart ischemia. (springer.com)
  • en.wikipedia.org /wiki/Pathophysiology_of_ heart . (yahoo.com)
  • The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle, through damage or overloading. (yahoo.com)
  • Patients with systolic heart failure usually have dilated, large ventricles and impaired systolic function. (bartleby.com)
  • Diastolic heart failure can occur alone or with systolic heart failure. (bartleby.com)
  • Symptoms of heart failure are often due to "congestion," but in some cases of moderate to severe systolic heart failure, symptoms can be due to the weak heart (or weak pumping action) without the presence of "congestion. (emoryhealthcare.org)
  • Other imaging tests can look at how well your heart is able to pump blood, and how much the heart muscle is damaged. (medlineplus.gov)
  • The condition, wherein the heart becomes too weak to effectively pump blood, afflicts millions of adults and costs billions of dollars to treat each year. (washingtonexaminer.com)
  • Heart failure is when the heart can't pump blood the way it should. (kidshealth.org)
  • This means the heart does not pump blood efficiently for the body to work well. (ipl.org)
  • This person has just suffered a heart attack and most likely will go on to develop heart failure, a weakening of the heart's ability to pump blood and oxygen. (nature.com)
  • The system synchronizes with a patient's pulse and quickly inflates after each heartbeat, adding pumping force to make it easier for the heart to pump blood throughout the body. (livescience.com)
  • Heart failure is a condition in which the heart cannot pump blood to meet the body's demands, this can have many causes, the most common being a heart attack. (www.nhs.uk)
  • As a result, the heart doesn't pump blood efficiently and a cat's body doesn't receive the proper amount of oxygen it needs. (vetinfo.com)
  • Heart failure is a common, costly, and potentially fatal condition, and it is the leading cause of both hospitalization and readmission amongst older adults. (wikipedia.org)
  • Over five million Americans suffer annually from heart failure - one of the most common causes of hospitalization and readmission - yet the medication most often prescribed may not be the most effective. (yaledailynews.com)
  • Women, Black adults and individuals with lower net worth are significantly more likely to be diagnosed with heart failure in an acute care setting such as the emergency room or during a hospitalization, even if they reported symptoms of heart failure during a routine, outpatient health care appointment during the previous six months, according to new research published today in Circulation: Heart Failure, an American Heart Association journal. (news-medical.net)
  • 9,10,11 Additionally, NT-proBNP, can be used for monitoring heart failure over time and identify which patients are stable or improving, and which are worsening and at high risk of hospitalization or mortality. (roche.com)
  • This study shows that we can accurately predict the likelihood of hospitalization for heart failure deterioration well before doctors and patients know that something is wrong," study co-author Josef Stehlik, co-chief of the advanced heart failure program at University of Utah Health, said in a press release. (upi.com)
  • Being able to readily detect changes in the heart sufficiently early will allow physicians to initiate prompt interventions that could prevent re-hospitalization and stave off worsening heart failure. (upi.com)
  • Despite interest in novel ways to improve exercise function in heart failure, "we should not yet view testosterone as the definitive answer," Yancy said, noting the lack of information about long-term cardiovascular effects of testosterone treatments. (go.com)
  • It may be possible that a newly discovered cardiovascular repair process could reverse heart failure. (medicalnewstoday.com)
  • Hirsh J, Hoak J. Management of deep vein thrombosis and pulmonary embolism: a statement for healthcare professionals: Council on Thrombosis (in consultation with the Council on Cardiovascular Radiology), American Heart Association. (springer.com)
  • Heart failure hospitalizations and costs related to methamphetamine use jumped sharply over a decade in California, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal. (news-medical.net)
  • The composite HeartScore is clearly viewable to patients to help real time guidance of their heart and cardiovascular health. (prnewswire.com)
  • G. C. Fonarow, "The acute decompensated heart failure national registry (ADHERE): opportunities to improve care of patients hospitalized with acute decompensated heart failure," Reviews in Cardiovascular Medicine , vol. 4, supplement 7, pp. (hindawi.com)
  • Ageing populations and deteriorating lifestyles mean heart failure is the most rapidly growing cardiovascular condition. (novartis.com)
  • During normal functioning of the cardiovascular system, blood arrives at the right atrium of the heart via the vena cava. (ipl.org)
  • For more information or to contact a cardiovascular nurse specialist, please call 941-917-8508 or email [email protected] . (smh.com)
  • The goal of Sarasota Memorial's outpatient Heart Failure Center is to optimize patients' cardiovascular health so they can live life to the fullest. (smh.com)
  • Unlike cardiomyocytes, fibroblasts have no pumping ability, so the heart gradually gets weaker and weaker, with the result that the majority of severe heart attack patients develop heart failure. (medicalnewstoday.com)
  • Vitamin-like nutrient CoQ10 can reduce mortality rates by half in patients with moderate to severe heart failure, researchers have concluded in what they say is the first adequately powered trial to do so. (nutraingredients-usa.com)
  • Heart transplants are a measure of last resort for people with severe heart failure when all other options have failed. (healthday.com)
  • These findings suggest that daily activity in patients with severe heart failure may not simply be limited by the failing heart, but also by an impairment in the leg muscles themselves. (leeds.ac.uk)
  • We don't want patients and their loved ones rushing to buy testosterone supplements online, or physicians to misinterpret the findings," said Ezekowitz, who led the meta-analysis published today in the American Heart Association's journal Circulation Heart Failure. (go.com)
  • A study from the American Heart Association's journal found that more exercise was better in preventing heart failure. (healthcentral.com)
  • Percentage of patients, regardless of age, discharged from an inpatient facility to ambulatory care or home health care with a principal discharge diagnosis of heart failure for whom a follow up appointment was scheduled and documented prior to discharge (as specified). (acponline.org)
  • The Framingham criteria for the diagnosis of heart failure consists of the concurrent presence of either two major criteria or one major and two minor criteria. (medscape.com)
  • Interpretation of the results provided by those tests helps in the confirmation or exclusion of the diagnosis of heart failure. (roche.com)
  • As the largest heart center in North Texas, we deliver compassionate care including specialized treatments to help even the sickest children feel better. (childrens.com)
  • Even if your child has a complex or hard to treat form of heart failure, he or she can get all the treatments they need right here at Children's Health. (childrens.com)
  • Correcting abnormal and dangerous heart rhythms using special treatments and devices. (childrens.com)
  • The doctor uses your test results to determine whether you have heart failure, the degree of severity, including the type of heart failure as well as the class of heart failure , you may be dealing with, and what treatments would be most effective. (heart.org)
  • Doctors use many different treatments to lower the workload of the heart. (seattlechildrens.org)
  • Better treatments for heart failure, comorbidities as well as depression itself may be required. (psychcentral.com)
  • If your heart function worsens over time, you may need to consider more advanced treatments. (emoryhealthcare.org)
  • Cleland said approximately 25 percent of patients admitted to hospital with heart failure are readmitted for a variety of reasons within one month. (psychcentral.com)
  • As many as 30 percent of patients discharged from the hospital with heart failure are readmitted within 90 days due to recurrent symptoms like shortness of breath, fatigue and fluid buildup. (upi.com)
  • Heart failure happens when the heart cannot pump enough blood and oxygen to support other organs in your body. (cdc.gov)
  • Heart failure is a condition in which the heart is no longer able to pump oxygen-rich blood to the rest of the body efficiently. (medlineplus.gov)
  • Another example is anemia, in which there is inadequate oxygen delivery to important body parts meaning the heart has to work harder and is put under starin to pump more oxygen around the body. (news-medical.net)
  • Ischemia may manifest in distinct ways, either as a result of increasing tissue oxygen demand, or diminished ability of the heart to supply oxygen to the tissue. (wikipedia.org)
  • Heart failure does not mean that the heart has stopped pumping, but it does mean that vital organs do not get the oxygen and nutrients they need to function properly. (medicalnewstoday.com)
  • One of the curious things about heart muscle is that it does not regenerate when it dies after being starved of oxygen, such as after a heart attack. (medicalnewstoday.com)
  • More than 23 million people worldwide have heart failure, which happens when the heart isn't strong enough to pump enough blood and oxygen through the body. (reuters.com)
  • Heart failure is when the heart is not functioning properly and becomes unable to supply the body properly with oxygen. (ipl.org)
  • The heart does not fail, but rather that it does not contract as strongly as before, and does not pump enough blood around the body to meet the body's needs in terms of oxygen. (ipl.org)
  • With obstructive sleep apnea, a person's breathing stops while sleeping, which can lead to less oxygen being delivered to the heart. (nationaljewish.org)
  • A normal healthy heart pumps enough oxygen-rich blood out of the heart and into the system to nourish all parts of the body. (emoryhealthcare.org)
  • Symptoms of heart failure may occur when the heart does not pump (eject blood) efficiently enough to meet these oxygen demands. (emoryhealthcare.org)
  • Treatment for heart failure depends on its severity. (adam.com)
  • Heart failure symptoms are related to the changes that occur to your heart and body, and the severity depends on how weak your heart is. (webmd.com)
  • The severity of the heart failure is graded by the severity of symptoms with exercise. (wikipedia.org)
  • Both antidiuretic hormone (ADH) release and the associated reduction in the serum sodium concentration parallel the severity of the heart failure [ 1 ]. (uptodate.com)
  • This included social, mental and physical frailty, as well as comorbidities and the severity of heart failure. (psychcentral.com)
  • The association remained once sex, age, high blood pressure, severity of heart failure, and comorbidities were taken into account. (psychcentral.com)
  • The association was independent of the severity of heart failure or the presence of comorbidities," Cleland added. (psychcentral.com)
  • The rate, types, and severity of cognitive impairment in this group of patients living with HF were similar to those seen in patients with end-stage HF awaiting heart transplantation. (psychcentral.com)
  • 1,2,7 Raised NT-proBNP levels in the blood can indicate that someone has heart failure 1,2,12 and levels tend to rise with the disease's severity. (roche.com)
  • The severity of your heart failure condition can change over time, for better or worse, requiring alterations in your treatment. (emoryhealthcare.org)
  • Determine the severity of your heart failure by taking into consideration what caused your heart problem to begin with (for example, a heart attack, long-standing high blood pressure, a virus, etc.) and how well you have responded to therapies. (emoryhealthcare.org)
  • The severity of your heart failure condition is ultimately determined by your heart's ability to do its job, your body's ability to adapt to these changes, and your ability to be a partner in your care. (emoryhealthcare.org)
  • Lower testosterone levels have been shown to be an independent risk factor for worse outcomes among men and women with heart failure. (go.com)
  • It uses a team-based approach and an electronic medical record (EMR) system to address the unique health and socioeconomic needs of heart failure patients at high risk for 30-day hospital readmission, improve the quality of care and health outcomes of these patients, and advances health equity. (cdc.gov)
  • The table below describes core components of (CVD) outcomes, including the Grady Heart Failure Program as described by leadership, staff, and partners. (cdc.gov)
  • When patients are admitted for inpatient services, they receive a the quality of care and 30-minute consultation with an APP and are given a self- outcomes of low-income, management tool, the Grady Heart Failure Survival Guide . (cdc.gov)
  • ProPublica and the Houston Chronicle are investigating troubles at Baylor St. Luke's in Houston, an illustrious heart program that has recently had some of the worst outcomes in the country. (propublica.org)
  • Heart failure patients with low vitamin C levels could be at higher risk of complications and may also have worse long term outcomes, according to a new research. (nutraingredients-usa.com)
  • An estimated 26 million people have heart failure worldwide, and for patients with acute decompensated heart failure, abnormal blood volume levels are directly linked to kidney failure, worsening outcomes, and increased mortality. (prnewswire.com)
  • Conditions, such as hypertension, that encourage increased left ventricular afterload can lead to structural changes in the heart on a gross , as well as a microscopic level. (wikipedia.org)
  • Learn how a robotic sleeve that mimics heart muscle may be more effective than ventricular assist devices in helping heart failure patients to live longer. (medicalnewstoday.com)
  • The increase in ventricular volume also causes a reduction in stroke volume due to mechanical and inefficient contraction of the heart. (wikipedia.org)
  • But Rose, who led a study of one such implant used in heart-failure treatment -- the left ventricular assist device -- is temperate in his enthusiasm. (medicinenet.com)
  • The former vice president's heart functions with the help of a left ventricular assist device (LVAD) that helps push blood through his body. (foxnews.com)
  • Left ventricular hypertrophy or LVH is the enlargement and thickening of the muscular wall of the left ventricle of the heart, the lower left chamber. (eurekalert.org)
  • Previous studies described a malignant type of left ventricular hypertrophy but did not include enough participants to enable researchers to conclude whether the observed differences in malignant LVH contribute to a higher risk of heart failure for black versus white individuals. (eurekalert.org)
  • Individuals with left ventricular hypertrophy were identified by ECG, and the malignant form of LVH was further defined as having abnormal blood marker levels reflecting injury or stress to the heart muscle. (eurekalert.org)
  • It develops when the heart cannot pump enough blood to meet the body's needs. (medicalnewstoday.com)
  • Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. (news-medical.net)
  • Over time this can weaken the heart muscles to the point they can no longer pump enough blood to meet the body's needs. (childrens.com)
  • This pro-inflammatory state may also induce changes in the vascular endothelium of the heart. (wikipedia.org)
  • The symptoms of heart failure come from pulmonary vascular congestion and inadequate perfusion of the systemic circulation. (bartleby.com)
  • Physicians need a way to identify complications linked to heart failure in their patients before they occur. (washingtonexaminer.com)
  • Heart failure is typically treated by loop diuretics, commonly known as water pills, which stimulate the kidneys to excrete excess salt and water to relieve fluid that builds up due to heart complications. (yaledailynews.com)
  • My dog had this and lived 5 years after she was diagnosed,she had other complications like a cough (consistent with heart failure) and would pass out when she would cough. (yahoo.com)
  • Potential complications include infection, bleeding, worsening heart failure and fracture of the leads implanted in the heart. (hon.ch)
  • Doctors generally prescribe a number of different types of medication to help with the symptoms and complications of heart failure. (healthday.com)
  • Risk assessment for incident heart failure in individuals with atrial fibrillation. (framinghamheartstudy.org)
  • Q In 2001, my doctor told me that I suffered from mitral-valve prolapse (MVP), and that this heart abnormality was behind the atrial fibrillation with which I had been diagnosed two years earlier. (healthy.net)
  • It typically results from narrowed arteries (atherosclerosis), heart attack, heart valve diseases or infections that weaken the heart muscle. (go.com)
  • This can weaken the heart muscle over time or suddenly. (medlineplus.gov)
  • The muscle contraction of the heart may weaken due to overloading of the ventricle with blood during diastole. (news-medical.net)
  • Doctors aren't exactly sure what caused his heart to weaken, but a lack of answers has done little to slow him down. (healthcentral.com)
  • Over time, these conditions weaken the heart and make its job more difficult. (nationaljewish.org)
  • Digitalis increases the pumping action of the heart, while diuretics help the body eliminate excess salt and water. (archive.org)
  • Doctors may be increasing the risk of heart failure among older patients if they are mixing diuretics with NSAIDs (non steroidal anti inflammatory drugs). (healthy.net)
  • In the present study we examined the relationship between hemodynamic changes and dyspnea relief (defined as moderate or marked improvement) using frequent measurements of hemodynamic parameters and simultaneous dyspnea assessments in patients with acute heart failure who were treated with vasodilators and diuretics. (ahajournals.org)
  • It can also occur suddenly as the result of damage to the heart muscle or an acute valve problem. (adam.com)
  • [12] Chest pain , including angina , does not typically occur due to heart failure. (wikipedia.org)
  • A reduced stroke volume may occur as a result of a failure of systole, diastole or both. (wikipedia.org)
  • Enlargement of the ventricles can also occur and contributes to the enlargement and spherical shape of the failing heart. (wikipedia.org)
  • Swelling caused by fluid buildup can occur in various places in the body, and your heart rate may increase. (healthday.com)
  • Early diagnosis and treatment can improve quality and length of life for people who have heart failure. (cdc.gov)
  • An in-depth report on the causes, diagnosis, treatment, and prevention of heart failure. (adam.com)
  • The AHA notes that while technology has increased the treatment options for advanced heart failure, "doing everything is not always the right thing. (adam.com)
  • Since the advent of effective treatment strategies for heart attackin the 1970's, research into the causative factors of heart conditions and ways to refine thetreatment options have been proceeding at a very rapid pace.Along with the knowledge about the pathological process leading to the heart attack (In Frenchattaque cardiaque)came the information about the risk factors - primarily diabetes,hypertension, hypercholesterolemia and smoking. (slideshare.net)
  • While that doesn't necessarily mean Americans don't benefit at all, it does question heart failure treatment guidelines, which often rely on international trials. (ibtimes.com)
  • Treatment can help with heart failure and sometimes cure it completely. (kidshealth.org)
  • People who are just beginning treatment for high blood pressure can benefit equally from two different classes of medicine - angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) - yet ARBs may be less likely to cause medication side effects, according to an analysis of real-world data published today in Hypertension, an American Heart Association journal. (news-medical.net)
  • A potentially life-saving treatment for heart attack victims has been discovered from a very unlikely source - the venom of one of the world's deadliest spiders. (news-medical.net)
  • This does not preclude the possibility of a modest mortality benefit from revascularization, a conclusion consistent with the Surgical Treatment for Ischaemic Heart Failure trial (STICH), which showed that CABG did not reduce all-cause mortality in patients with HF-REF, although there was a borderline-significant reduction in CV death. (medscape.com)
  • Adoption of a simple 'Universal Definition' of heart failure based on natriuretic peptides would facilitate early diagnosis and treatment but lead to an enormous increase in its prevalence and demand upon medical services. (medscape.com)
  • Technological breakthroughs are changing the course of heart -failure treatment -- but doubts remain about how many people will benefit in the near future. (medicinenet.com)
  • But the last few years have witnessed a surge in both the types of devices being tested for heart-failure treatment, and in the optimism of experts about their usefulness. (medicinenet.com)
  • It remains to be seen how widely and how quickly these life-saving implants will become available for routine heart-failure treatment. (medicinenet.com)
  • Of course, there is a potential disadvantage to having an ICD for heart-failure treatment: If the experience of being shocked by a box in your chest doesn't sound pleasant, you're right. (medicinenet.com)
  • One in 5 people aged 40 and over will develop heart failure in their lifetime and the treatment costs are estimated at $65 billion a year worldwide. (novartis.com)
  • For Hartshorne-Evans, who runs The Pumping Marvellous Foundation, a patient-led support organization in the United Kingdom for people with heart failure, the low survival rates underline the need for new treatment options to improve the outlook for patients as they seek to maintain their quality of life. (novartis.com)
  • Treatment for heart failure begins with lifestyle changes and medications. (hopkinsmedicine.org)
  • The goal of heart failure treatment is to improve quality of life by addressing the underlying causes, reducing symptoms and managing overall health. (hopkinsmedicine.org)
  • Accurately diagnosing heart failure helps us understand more about your child's condition so we can make sure he or she gets the best treatment possible. (childrens.com)
  • Care often begins before a child is born, when a congenital heart defect is diagnosed through our Prenatal Diagnosis and Treatment Program. (seattlechildrens.org)
  • This graphic illustrates a potential breakthrough in the treatment of heart failure patients. (livescience.com)
  • This is an early indication that the C-Pulse may be able to reverse or prevent the progression of heart failure, offering advantages over other treatment options. (livescience.com)
  • Also, a larger trial (The Surgical Treatment for Ischemic Heart Failure Trial) addressing a similar question became available, which investigators were encouraged to join. (nih.gov)
  • A drug found to be extremely effective in the treatment of Leukaemia and some stomach cancers could cause heart failure, research suggests. (netdoctor.co.uk)
  • Dr. Fariba Yaghoubinia and colleagues at the Zahedan University of Medical Sciences, Iran, said psychological factors affect the onset, exacerbation, and treatment of heart failure. (psychcentral.com)
  • A heart failure diagnosis may sound frightening, but with the right treatment, a heart failure condition can be controlled. (emoryhealthcare.org)
  • But you will need tests to find the cause and type of heart failure so that you can get the right treatment. (rexhealth.com)
  • She has devoted her career to the individualized treatment of heart failure, and finding a combination of therapies that works for the individual patient. (ohsu.edu)
  • The sensors are placed under the patient's bed to track his or her heart rate. (washingtonexaminer.com)
  • This latest study suggests that secondhand smoke may also affect a heart failure patient's quality of life, according to the researchers, led by Dr. Kirsten E. Fleischmann of the University of California, San Francisco. (reuters.com)
  • The system is synced with a patient's pulse so that it quickly inflates after each heartbeat to help squeeze blood out of the heart. (livescience.com)
  • Now, many medical experts are touting the benefits of a new mechanical pump that gives a patient's own heart a new lease on life. (wsj.com)
  • When the data deviated from normal, the platform generated an indication to doctors that the patient's heart failure was getting worse. (upi.com)
  • Unhealthy behaviors can also increase your risk for heart failure, especially for people who have one of the conditions listed above. (cdc.gov)
  • People with heart failure also track their symptoms each day so that they can discuss these symptoms with their health care team. (cdc.gov)
  • People with heart failure can't exert themselves because they become short of breath and tired. (archive.org)
  • Heart failure symptoms are traditionally divided into left- and right-sided, recognizing that the left and right ventricles of the heart supply different portions of the circulation, but people commonly have both sets of signs and symptoms. (wikipedia.org)
  • An echocardiogram (echo) is most often the best first test for people when heart failure is being evaluated. (medlineplus.gov)
  • By using Heart Failure Health Storylines, you have the opportunity to anonymously contribute learning from your story to a vital data resource that the healthcare industry can use to improve care in the future, for people like you. (apple.com)
  • Would be nice to be able to talk to people with heart failure in a safe and effective way. (apple.com)
  • In the new work, researchers drive that point home for drugs known as beta blockers, which gold-standard tests have shown can extend the life of people with heart failure. (ibtimes.com)
  • Heart failure afflicts far too many people already. (washingtonexaminer.com)
  • Heart failure affects 26 million people worldwide. (novartis.com)
  • More people die from heart failure than from some advanced cancers, including breast and bowel cancer. (novartis.com)
  • Yet for many people living with heart failure, everyday activities like walking and climbing stairs can become increasingly difficult. (novartis.com)
  • People can and do live with heart failure. (hopkinsmedicine.org)
  • People can develop heart failure due to a condition that damages the heart muscle, like a heart attack or poorly controlled high blood pressure. (reuters.com)
  • People with heart failure have been found to have less gut bacteria diversity and lack certain important species groups. (nutraingredients-usa.com)
  • In some people with heart failure, the lower chambers of the heart don't beat at the same time, forcing the heart to work harder. (medtronic.com)
  • This review of five large studies questioned people about how much coffee they drank and then examined whether they went on to develop heart failure. (www.nhs.uk)
  • Because some of the studies included people who had already had a heart attack, it is not clear whether they were currently in some stage of heart failure when their coffee drinking was assessed. (www.nhs.uk)
  • This was a systematic review and meta-analysis of studies that looked at the association between risk of heart failure and the number of cups of coffee people reported drinking. (www.nhs.uk)
  • John Tesmer, research professor at the U-M Life Sciences Institute and professor in the Department of Pharmacology at the U-M Medical School, and his research team at the Tesmer lab found that paroxetine, a selective serotonin reuptake inhibitor (SSRI) sold under the name Paxil, inhibits G protein-coupled receptor kinase 2 (GRK2), a protein kinase that becomes over-expressed when people have heart failure. (newswise.com)
  • Depression raises the risk of death among people with heart failure, according to recent research. (psychcentral.com)
  • Roughly 550,000 people are diagnosed with heart failure each year (Emory Healthcare, 2014). (bartleby.com)
  • Abstract: Heart failure affects over 5 million people and carries a high rate of mortality. (bartleby.com)
  • Diastolic heart failure is mainly common in elderly people with age of 65 or older. (bartleby.com)
  • Researchers reported that the chance of death was reduced by 30 percent, heart-related hospitalizations were reduced by 32 percent, and declines in quality of life were slowed for people who received the drug versus those who received a placebo. (healthline.com)
  • The British Heart Foundation is to begin a major new research programme to find a cure for heart failure, a condition affecting 750,000 UK people. (bbc.co.uk)
  • Professor Peter Weissberg, medical director at the BHF, said: 'Since the BHF's inception 50 years ago, we've made great strides in medical research to better diagnose and treat people with all kinds of heart problems. (bbc.co.uk)
  • But the biggest issue that still eludes us is how to help people once their heart has been damaged by a heart attack. (bbc.co.uk)
  • Some people have both types of heart failure simultaneously. (healthday.com)
  • Thus, people who have problems that lead to these issues -- such as those who are obese or those who've had a heart attack -- are also at risk for heart failure. (healthday.com)
  • But many people with heart failure lead a full, enjoyable life when the condition is managed with heart failure medications and healthy lifestyle changes . (heart.org)
  • The body's compensation mechanisms help explain why some people may not become aware of their condition until years after their heart begins its decline. (heart.org)
  • Most people with heart failure need to take several medicines. (rexhealth.com)
  • At OHSU, we care for people with all types and stages of heart failure. (ohsu.edu)
  • Knowing your body and the symptoms that your heart failure is getting worse will help you stay healthier and out of the hospital. (medlineplus.gov)
  • Weight gain, especially over a day or two, can be a sign that your body is holding on to extra fluid and your heart failure is getting worse. (medlineplus.gov)
  • This makes the condition worse as the heart muscles require more nutrients to work and the myocardial muscles pump at an increased rate. (news-medical.net)
  • In general, the higher the BNP levels, the worse the heart failure. (hopkinsmedicine.org)
  • If your heart failure is caused or made worse by a weak valve, your doctor may consider heart surgery to repair or replace the valve. (medtronic.com)
  • Evaluate if there are any extra work demands on your heart that can make your condition worse , like, obesity and untreated high blood pressure. (emoryhealthcare.org)
  • The booklet also advises those with heart failure on ways to feel better each day, as well as providing care reminders, and an emergency plan in case symptoms get worse. (heartfoundation.org.au)
  • Heart failure usually gets worse over time. (rexhealth.com)
  • Your doctor can also use it to see if your heart failure is getting worse. (rexhealth.com)
  • If you don't, your heart failure could get worse. (rexhealth.com)
  • With the stress of traveling, eating lots of high-salt foods, and the lack of exercise while celebrating can all lead to weight gain and fluid retention, causing heart failure symptoms to get worse, requiring a trip to the hospital. (redorbit.com)
  • There is a lot of interest in the role ofstem cells in the repair of dead heart muscle cells. (slideshare.net)
  • Your heart muscle cannot contract very well. (medlineplus.gov)
  • Your heart muscle is stiff and does not fill up with blood easily even though pumping power is normal. (medlineplus.gov)
  • Initially the heart muscle fibres increase in size to improve contractility but with time they become too stiff and unyielding to be of any benefit. (news-medical.net)
  • Scientists may have discovered a way of reversing heart failure by getting heart muscle to regenerate itself. (medicalnewstoday.com)
  • Instead of generating new beating muscle cells, or cardiomyocytes, the heart replaces the dead tissue with scar tissue made from fibroblast cells. (medicalnewstoday.com)
  • Prof. Martin says that he and his laboratory team are studying biological pathways that are active during heart development and regeneration in order to find ways to heal heart muscle. (medicalnewstoday.com)
  • In this study, we investigated the Hippo pathway, which is known from my lab's previous studies to prevent adult heart muscle cell proliferation and regeneration," Prof. Martin notes. (medicalnewstoday.com)
  • The researchers believe that silencing Hippo not only renews heart muscle cells - as investigated extensively in their study - but it also changes the process of fibrosis, or scarring. (medicalnewstoday.com)
  • Bioheart, Inc. - http://www.bioheartinc.com - Phase III leader in applying adult muscle stem cells to treat advanced heart failure since 1999. (prnewswire.com)
  • In heart failure, this mechanism fails, as the ventricle is loaded with blood to the point where heart muscle contraction becomes less efficient. (wikipedia.org)
  • This is due to reduced ability to cross-link actin and myosin filaments in over-stretched heart muscle. (wikipedia.org)
  • This is caused by the terminally differentiated heart muscle fibers increasing in size in an attempt to improve contractility. (wikipedia.org)
  • Heart failure does not signify our heart has failed or stopped up beating.It means that our heart, which is a muscle that pumps blood to all parts of our body, is not working as well as it should and cannot pump as much blood as our body needs. (ipl.org)
  • Certain illnesses and medical conditions can damage your child's heart muscle or make it work harder than it should. (childrens.com)
  • Contractility is the pumping of the heart muscle. (bartleby.com)
  • The charity hopes to harness the miraculous healing abilities of zebrafish, a species that is able to mend its own heart muscle. (bbc.co.uk)
  • The Mending Broken Hearts project will involve stem cell research and developmental biology to work out how to repair or replace damaged heart muscle. (bbc.co.uk)
  • Anything that causes extra work demands for your weakened heart muscle needs to be addressed so that your heart function has the opportunity to improve, or at least stabilize to afford you the best possible quality of life. (emoryhealthcare.org)
  • Calcium channel blockers slow down the rate in which calcium passes through the heart muscle and into the vessel walls. (vetinfo.com)
  • Heart failure means that your heart muscle doesn't pump as much blood as your body needs. (rexhealth.com)
  • Diseases of the heart muscle (cardiomyopathies). (rexhealth.com)
  • Your heart is a muscle, and sometimes that muscle can fail. (ohsu.edu)
  • It could be a question of different use of medications or devices to control heart failure, or it could be a chance finding because only one study included a large proportion of U.S. patients, the researchers write. (ibtimes.com)
  • Researchers at the University of Missouri, for example, have developed sensors that can predict heart problems. (washingtonexaminer.com)
  • The researchers obtained data on heart failure hospitalizations through the database Premier Inc. (yaledailynews.com)
  • Researchers evaluated heart failure risk in adults who were adopted to assess the impact of genetic and environmental factors on heart failure risk. (healthcentral.com)
  • Researchers found that of 205 non-smokers with heart failure, those who regularly breathed in secondhand smoke reported more problems in their day-to-day functioning -- physical and emotional. (reuters.com)
  • The findings are based on questionnaires and tests from 205 heart failure patients at the researchers' medical center. (reuters.com)
  • A new study led by researchers at The Ohio State University Wexner Medical Center showed that the device slowed or reversed symptoms in several heart failure patients during the first round of tests in the United States. (livescience.com)
  • Researchers found that the drug targeted proteins necessary for maintaining heart health, increasing the risk of heart failure. (netdoctor.co.uk)
  • Newswise - ANN ARBOR-A medication usually used to help treat depression and anxiety disorders has the potential to help prevent heart failure, according to researchers at the University of Michigan. (newswise.com)
  • Researchers say the heart attack known as MINOCA doesn't involve obstructed arteries and is often dismissed as minor by medical professionals. (healthline.com)
  • DALLAS - Jan. 14, 2020 - Researchers at UT Southwestern have uncovered evidence that the higher prevalence of "malignant" enlargement of the heart among blacks contributes to the higher incidence of heart failure in this population. (eurekalert.org)
  • So the UT Southwestern researchers pooled data from three biracial cohort studies - the Atherosclerosis Risk in Communities (ARIC) Study, the Dallas Heart Study, and the Multi-Ethnic Study of Atherosclerosis (MESA) - to test the hypothesis that malignant LVH may contribute to disparities in heart failure risk. (eurekalert.org)
  • The muscles then fail to function normally, increasing the risk of heart failure. (news-medical.net)
  • Reuters Health) - Men who drink two or more glasses of soda or other sweetened drinks a day may have a greater risk of heart failure, a Swedish study suggests. (reuters.com)
  • Obesity and the risk of heart failure," The New England Journal of Medicine , vol. 347, no. 5, pp. 305-313, 2002. (hindawi.com)
  • Lipoprotein-associated phospholipase A2 activity and risk of heart failure: the Rotterdam study," European Heart Journal , vol. 27, no. 19, pp. 2346-2352, 2006. (hindawi.com)
  • Daily supplements of the sunshine vitamin may reduce the risk of heart failure in older individuals by 20%-25%, says a new study. (nutraingredients-usa.com)
  • Antioxidant-rich diet may reduce the risk of heart failure, but what about supplements? (nutraingredients-usa.com)
  • A diet rich in antioxidants may reduce a woman's risk of heart failure by 42%, suggests new data from 33,713 Swedish women. (nutraingredients-usa.com)
  • Consuming fish at least once a month, and increased blood levels of ALA and DPA, may reduce the risk of heart failure, says a new study that adds to the heart health benefits of omega-3. (nutraingredients-usa.com)
  • Increased intakes of omega-3s and higher blood levels of the fatty acids are associated with a 15% decrease in the risk of heart failure, says a new meta-analysis. (nutraingredients-usa.com)
  • Two cups of coffee a day can reduce the risk of heart failure (but five can be bad for you)," the Daily Mail reported today. (www.nhs.uk)
  • This seemingly contradictory headline is actually a fair but slightly overenthusiastic reflection of a review of research that looked at the relationship between regular coffee drinking and risk of heart failure. (www.nhs.uk)
  • Overall, this review does not prove that coffee is good for the heart - only a possible association between coffee drinking and the risk of heart failure. (www.nhs.uk)
  • Both the Daily Express and the Mail said that two cups of coffee can reduce the risk of heart failure, but this number appears to be a conversion of US serving sizes and servings in coffee chains. (www.nhs.uk)
  • The Express claim that coffee 'can dramatically reduce the risk of heart failure' was not borne out by this research, which found a relatively small decrease in risk associated with moderate coffee drinking. (www.nhs.uk)
  • A systematic review and meta-analysis of prospective cohort studies is the best way of identifying and combining the results of all relevant research that has addressed the question of whether a coffee drinking is associated with the risk of heart failure. (www.nhs.uk)
  • Zapol WM, Snider MT. Pulmonary hypertension in severe acute respiratory failure. (springer.com)
  • A weak heart pumps less blood to your kidneys and causes fluid and water retention, resulting in swollen ankles , legs, and abdomen (called edema ) and weight gain. (webmd.com)
  • Edema, the accumulation of excess fluid in body tissues, is often a symptom of heart failure. (wikihow.com)
  • listening to your heart and lung sounds, looking at and touching your skin, feeling for a presence of fluid and signs that may indicate heart or lung problems, and other exams as needed. (emoryhealthcare.org)
  • Fluid intake plays a role in heart failure management but it can be hard for some patients to self-manage. (heartfoundation.org.au)
  • 2 This total includes the cost of health care services, medicines to treat heart failure, and missed days of work. (cdc.gov)
  • to health prevent heartfailure. (slideshare.net)
  • By helping patients provide continuous care overcome these barriers, the program can reduce rates of 30- for hundreds of patients day hospital readmissions and improve the quality of care and with heart failure health of heart failure patients. (cdc.gov)
  • Heart Failure Health Storylines is developed in partnership with the Heart Failure Society of America, and is powered by the Health Storylines™ platform from Self Care Catalysts Inc. (apple.com)
  • Sweetened beverages lead to weight gain and obesity and this leads to diabetes and heart failure," Martinez-Gonzalez told Reuters Health by email. (reuters.com)
  • Epidemiology of incident heart failure in a contemporary elderly cohort the health, aging, and body composition study," Archives of Internal Medicine , vol. 169, no. 7, pp. 708-715, 2009. (hindawi.com)
  • What are the pros and cons of taking fish oil for heart health? (medhelp.org)
  • When your child has heart failure, you may feel as if you are running out of options, but Children's Health℠ can help. (childrens.com)
  • A combination of coenzyme Q10 and an extract from French Maritime Pine bark may improve blood flow and general heart health in heart failure patients, indicates a new study from Italy. (nutraingredients-usa.com)
  • The relationship between coffee consumption and heart health remains confusing, with previous studies showing inconsistent results. (www.nhs.uk)
  • Patients for whom a follow-up appointment for an office or home health visit for management of heart failure was scheduled within 7 days post-discharge and documented including location, date, and time. (acponline.org)
  • The Atkins and keto diets load up on protein, but the risk to your heart health might not be worth it. (healthline.com)
  • All health/medical information on this website has been reviewed and approved by the American Heart Association, based on scientific research and American Heart Association guidelines. (heart.org)
  • I also have a therapist to help me manage my mental health, which is something I struggled with even before I developed heart failure. (redorbit.com)
  • A new monitoring device, consisting of a disposable sensor patch with a disposable battery and a reusable sensor electronics module, may help track health of heart failure patients. (upi.com)
  • It was published in the peer-reviewed medical journal Circulation Heart Failure. (www.nhs.uk)
  • Heart failure is a condition in which the heart does not pump enough blood to meet the needs of the body's tissues. (adam.com)
  • Arteries carry blood away from the heart while veins carry blood into the heart. (adam.com)
  • As blood flow out of the heart slows, blood returning to the heart through the veins backs up, causing congestion in the tissues. (archive.org)
  • The heart beats faster to pump enough blood to the body. (webmd.com)
  • The heart is a hollow muscular organ that pumps blood around the body. (nottingham.ac.uk)
  • Heart failure is a condition where the heart fails to pump and circulate an adequate supply of blood to meet the requirements of the body. (news-medical.net)
  • If the volume at the end of diastole is decreased, it means less blood is entering the heart during diastole. (news-medical.net)
  • In those with HFpEF, the left ventricle of the heart (large chamber on right side of the picture) is stiffened and has impaired relaxation after pumping blood out of the heart. (wikipedia.org)
  • Some five million Americans are living with heart failure, in which the heart fails to pump enough blood into the body. (ibtimes.com)
  • Heart failure (HF) is one of the most serious conditions primary care providers treat, and Americans over the age of 40 with high blood pressure have a 20 percent lifetime risk. (ohsu.edu)
  • And blood backs up in the heart. (kidshealth.org)
  • What Happens When Blood Backs Up in the Heart? (kidshealth.org)
  • Too much blood flows through the heart (for example, from a congenital heart defect or severe anemia ). (kidshealth.org)
  • Previous research has linked high consumption of sugary beverages with several risk factors for heart failure, including high blood pressure, high blood sugar, weight gain, diabetes and obesity, said study leader Susanna Larsson of the Karolinska Institute in Stockholm. (reuters.com)
  • This helps restore blood pressure but also increases the total peripheral resistance, increasing the workload of the heart. (wikipedia.org)
  • Rather than a sudden, total failure of the heart, it is a progressive weakening characterized by an inability of the heart to pump enough blood around the body. (novartis.com)
  • These include personalized care planning to foster greater patient involvement in managing their conditions, while implantable devices are being designed to regulate the heart rate or check the blood pressure, providing physicians with early warning of a worsening condition. (novartis.com)
  • Heart Failure Heart failure is a condition in which the heart has trouble pumping blood because it has become weak or stiff. (ipl.org)
  • Heart failure is a genuine condition in which the heart is not pumping blood around the body effectively. (ipl.org)
  • Your child has weak heart muscles that aren't able to push enough blood to their body. (childrens.com)
  • Your child's heart pumps well, but doesn't move blood efficiently through their heart. (childrens.com)
  • Heart failure is a condition in which the pumping mechanism of the heart is weakened, and it is unable to circulate blood at a normal pace. (wikihow.com)
  • As a response, your body diverts blood away from organs that are less vital, particularly muscles in the limbs, and sends it to organs that are more vital, like the heart and brain. (wikihow.com)
  • The studies were inconsistent in how they adjusted for other factors that can be related to heart failure risk, such as high blood pressure and obesity. (www.nhs.uk)
  • The prime causes are conditions that damage the heart, such as high blood pressure and diabetes, the FDA said Thursday in a news release. (hon.ch)
  • Heart failure is a pathologic state where the heart cannot pump enough blood to meet the demand of the body's metabolic needs or when the ventricle's ability to fill is impaired. (bartleby.com)
  • 1,2 These are an electrocardiogram (ECG), a biomarker (blood test) for natriuretic peptides, and echocardiography to determine any structural and functional impairment of the heart (changes in heart beat rhythm, pumping capacity, wall stress and wall thickness). (roche.com)
  • If a patient presents with NT-proBNP in his or her blood, then heart failure diagnosis is highly likely, unless the level of the peptide is below a certain threshold. (roche.com)
  • When NT-proBNP levels in the blood are low, heart failure can be excluded. (roche.com)
  • As the first technology capable of directly measuring blood volume, changes in blood volume and kidney function, FAST BioMedical's metrics could be a significant advancement for managing volume and volume-related kidney injury patients with acute decompensated heart failure. (prnewswire.com)
  • This new technology could enable us to quantify and follow blood volume and kidney function in complex heart failure patients, including those patients at risk of developing cardiorenal syndrome,' said Dr. W, Frank Peacock , MD, FACEP, FACC, FESC and Associate Chief of Emergency Medicine Research at Baylor College of Medicine. (prnewswire.com)
  • in others, the heart does not fill with an adequate supply of blood. (healthday.com)
  • As heart failure advances, you may need a device like a pacemaker implanted into the body to assist your body in pumping blood properly. (healthday.com)
  • With heart failure, the weakened heart can't supply the cells with enough blood. (heart.org)
  • The heart stretches to contract more strongly and keep up with the demand to pump more blood. (heart.org)
  • The body diverts blood away from less important tissues and organs (like the kidneys), and towards the heart and brain. (heart.org)
  • High blood pressure is a risk factor for heart failure. (heartfoundation.org.au)
  • Symptoms of heart failure start to happen when your heart cannot pump enough blood to the rest of your body. (rexhealth.com)
  • This test can measure how much blood your heart pumps to your body. (rexhealth.com)
  • All three studies included height, weight, blood pressure, and blood test results as well as electrocardiogram results, a measure of the electrical activity of the heart. (eurekalert.org)
  • when myocytes fail to relax appropriately, myosin cross bridges remain intact and generate tension throughout diastole and thus increase stress on the heart. (wikipedia.org)
  • Heart Fail Rev. 2010 Jul;15(4):331-41. (nih.gov)
  • The heart has four chambers, a left atrium and right atrium and a left ventricle and right ventricle. (kidshealth.org)
  • The left ventricle supplies most of the heart 's pumping power, so it 's larger than the other chambers and essential for normal function. (ipl.org)
  • The ventricles are the major pumps in the heart. (adam.com)
  • The heart is really two pumps connected in series - the left and right sides. (nottingham.ac.uk)
  • Procyrion Implantable Heart Pumps - www.procyrion.com - The Procyrion device consists of a small, continuous flow pump mounted within a self-expanding anchoring system. (prnewswire.com)
  • Anything that damages your heart or affects how well it pumps can lead to heart failure. (rexhealth.com)
  • Learn the signs and symptoms of heart failure with this animated tool. (archive.org)
  • Signs and symptoms of heart failure commonly include shortness of breath, excessive tiredness, and leg swelling. (wikipedia.org)