Heart: The hollow, muscular organ that maintains the circulation of the blood.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Rheumatic Heart Disease: Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Heart Transplantation: The transference of a heart from one human or animal to another.Fetal Heart: The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.Heart Valves: Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.Carcinoid Heart Disease: Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.Cloning, Organism: The formation of one or more genetically identical organisms derived by vegetative reproduction from a single cell. The source nuclear material can be embryo-derived, fetus-derived, or taken from an adult somatic cell.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Heart Atria: The chambers of the heart, to which the BLOOD returns from the circulation.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.Heart Block: Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Heart Function Tests: Examinations used to diagnose and treat heart conditions.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Risk: The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Optical Storage Devices: A computer disk read by a laser beam, containing data prerecorded by a vendor. The buyer cannot enter or modify data in any way but the advantages lie in the speed of accessibility, relative immunity to damage, and relatively low cost of purchase.Heart Arrest, Induced: A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).Heart Septal Defects: Abnormalities in any part of the HEART SEPTUM resulting in abnormal communication between the left and the right chambers of the heart. The abnormal blood flow inside the heart may be caused by defects in the ATRIAL SEPTUM, the VENTRICULAR SEPTUM, or both.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Proportional Hazards Models: Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.United StatesRetrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Dental Restoration, Temporary: A prosthesis or restoration placed for a limited period, from several days to several months, which is designed to seal the tooth and maintain its position until a permanent restoration (DENTAL RESTORATION, PERMANENT) will replace it. (From Jablonski, Dictionary of Dentistry, 1992)Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Cholesterol, HDL: Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol.Infant, Newborn: An infant during the first month after birth.Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Cholesterol: The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Exercise Test: Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Adrenergic beta-Antagonists: Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Heart Valve Prosthesis: A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.Cardiac Surgical Procedures: Surgery performed on the heart.Cardiotonic Agents: Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.American Heart Association: A voluntary organization concerned with the prevention and treatment of heart and vascular diseases.Lipids: A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)Heart Septal Defects, Ventricular: Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.Mortality: All deaths reported in a given population.Pulmonary Heart Disease: Hypertrophy and dilation of the RIGHT VENTRICLE of the heart that is caused by PULMONARY HYPERTENSION. This condition is often associated with pulmonary parenchymal or vascular diseases, such as CHRONIC OBSTRUCTIVE PULMONARY DISEASE and PULMONARY EMBOLISM.Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.TriglyceridesJapanTetralogy of Fallot: A combination of congenital heart defects consisting of four key features including VENTRICULAR SEPTAL DEFECTS; PULMONARY STENOSIS; RIGHT VENTRICULAR HYPERTROPHY; and a dextro-positioned AORTA. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing CYANOSIS.Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Heart Septum: This structure includes the thin muscular atrial septum between the two HEART ATRIA, and the thick muscular ventricular septum between the two HEART VENTRICLES.Natriuretic Peptide, Brain: A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.Ventricular Remodeling: The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.Myocardial Reperfusion Injury: Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.FinlandOdds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Heart Septal Defects, Atrial: Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.Exercise: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Heart Failure, Systolic: Heart failure caused by abnormal myocardial contraction during SYSTOLE leading to defective cardiac emptying.Age Distribution: The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Diabetes Complications: Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.Heart Injuries: General or unspecified injuries to the heart.Great BritainHeart, Artificial: A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)Diastole: Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.Systole: Period of contraction of the HEART, especially of the HEART VENTRICLES.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Electrocardiography, Ambulatory: Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.Heart Failure, Diastolic: Heart failure caused by abnormal myocardial relaxation during DIASTOLE leading to defective cardiac filling.ScotlandDisease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Oxygen Consumption: The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.Heart Rate, Fetal: The heart rate of the FETUS. The normal range at term is between 120 and 160 beats per minute.Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.Diet: Regular course of eating and drinking adopted by a person or animal.Hospitalization: The confinement of a patient in a hospital.Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.Epidemiologic Methods: Research techniques that focus on study designs and data gathering methods in human and animal populations.Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Autonomic Nervous System: The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.Life Style: Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)Northern IrelandObesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Anti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).Hyperlipidemias: Conditions with excess LIPIDS in the blood.WalesModels, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.Endocardium: The innermost layer of the heart, comprised of endothelial cells.Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Reference Values: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.EnglandDenmarkEuropean Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Europe.Ventricular Dysfunction: A condition in which HEART VENTRICLES exhibit impaired function.Diabetic Angiopathies: VASCULAR DISEASES that are associated with DIABETES MELLITUS.Heterotaxy Syndrome: Abnormal thoracoabdominal VISCERA arrangement (visceral heterotaxy) or malformation that involves additional CONGENITAL HEART DEFECTS (e.g., heart isomerism; DEXTROCARDIA) and/or abnormal SPLEEN (e.g., asplenia and polysplenia). Irregularities with the central nervous system, the skeleton and urinary tract are often associated with the syndrome.Anticholesteremic Agents: Substances used to lower plasma CHOLESTEROL levels.National Heart, Lung, and Blood Institute (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports research program related to diseases of the heart, blood vessels, lung, and blood; blood resources; and SLEEP WAKE DISORDERS. From 1948 until October 10, 1969, it was known as the National Heart Institute. From June 25, 1976, it was the National Heart and Lung Institute. Since October 1997, the NHLBI has also had administrative responsibility for the NIH Woman's Health Initiative.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Heart Neoplasms: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.C-Reactive Protein: A plasma protein that circulates in increased amounts during inflammation and after tissue damage.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Hypolipidemic Agents: Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.Fibrinogen: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.Heart Valve Prosthesis Implantation: Surgical insertion of synthetic material to repair injured or diseased heart valves.Heart Ventricles: The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.Sympathetic Nervous System: The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Social Class: A stratum of people with similar position and prestige; includes social stratification. Social class is measured by criteria such as education, occupation, and income.Antihypertensive Agents: Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.Hydroxymethylglutaryl-CoA Reductase Inhibitors: Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.Linear Models: Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.Glia Maturation Factor: A factor identified in the brain that influences the growth and differentiation of NEURONS and NEUROGLIA. Glia maturation factor beta is the 17-kDa polypeptide product of the GMFB gene and is the principal component of GLIA MATURATION FACTOR.Confidence Intervals: A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.Pulmonary Artery: The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.Body Mass Index: An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Chromosome Segregation: The orderly segregation of CHROMOSOMES during MEIOSIS or MITOSIS.Type A Personality: Established behavior pattern characterized by excessive drive and ambition, impatience, competitiveness, sense of time urgency, and poorly contained aggression.Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Alcohol Drinking: Behaviors associated with the ingesting of alcoholic beverages, including social drinking.Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.SwedenCardiac Care Facilities: Institutions specializing in the care of patients with heart disorders.Pacemaker, Artificial: A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).Geriatric Nursing: Nursing care of the aged patient given in the home, the hospital, or special institutions such as nursing homes, psychiatric institutions, etc.Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.Eisenmenger Complex: A condition associated with VENTRICULAR SEPTAL DEFECT and other congenital heart defects that allow the mixing of pulmonary and systemic circulation, increase blood flow into the lung, and subsequent responses to low oxygen in blood. This complex is characterized by progressive PULMONARY HYPERTENSION; HYPERTROPHY of the RIGHT VENTRICLE; CYANOSIS; and ERYTHROCYTOSIS.African Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Africa.14-alpha Demethylase Inhibitors: Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.Endomyocardial Fibrosis: A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.Vasodilator Agents: Drugs used to cause dilation of the blood vessels.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Health Surveys: A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.Dietary Fats: Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.Propanolamines: AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.Mitral Valve Insufficiency: Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.Dithionitrobenzoic Acid: A standard reagent for the determination of reactive sulfhydryl groups by absorbance measurements. It is used primarily for the determination of sulfhydryl and disulfide groups in proteins. The color produced is due to the formation of a thio anion, 3-carboxyl-4-nitrothiophenolate.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Polymorphism, Genetic: The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.Calcinosis: Pathologic deposition of calcium salts in tissues.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Anti-heart autoantibodies in ischaemic heart disease patients. (1/4783)
One hundred and ninety-nine ischaemic heart disease (IHD) patients were studied with regard to the prevalence of anti-heart autoantibodies (AHA). The incidence of AHA in IHD patients was 1%: one out of 102 patients who suffered acute myocardial infarction (AMI), one out of seventy-two patients who suffered from acute coronary insufficiency (ACI), and none out of twenty-five patients with other signs and symptoms of IHD, had AHA in their sera. An additional 2% of patients who suffered from AMI developed detectable antibody levels during a follow-up period of 15 days. In comparison,, 53% of patients (eight out of fifteen) who underwent heart surgery and who had no AHA prior to operation, developed these antibodies in their sera during 1-2 weeks following operation. (+info)Failing firefighters: a survey of causes of death and ill-health retirement in serving firefighters in Strathclyde, Scotland from 1985-94. (2/4783)
During the decade beginning 1 January 1985, 887 full-time firefighters, all male, left the service of Strathclyde Fire Brigade (SFB). There were 17 deaths--compared to 64.4 expected in the Scottish male population aged 15-54 years--giving a standardized mortality ratio (SMR) of 26, and 488 ill-health retirements (IHR). None of the deaths was attributable to service, the major causes being: myocardial infarction--five, (expected = 17.3; SMR = 29); cancers--three (colon, kidney and lung) (expected = 13.6; SMR = 22); road traffic accidents--two (expected = 4.17; SMR = 48) and suicide--two (expected = 4.9; SMR = 41). Amalgamating the deaths and IHRs showed that the six most common reasons for IHR were musculoskeletal (n = 202, 40%), ocular (n = 61, 12.1%), 'others' (n = 58, 11.5%), injuries (n = 50, 9.9%), heart disease (n = 48, 9.5%) and mental disorders (n = 45, 8.9%). Over 300 IHRs (over 60%) occurred after 20 or more years service. When the IHRs were subdivided into two quinquennia, there were 203 and 302 in each period. Mean length of service during each quinquennium was 19.4 vs. 21.3 years (p = 0.003) and median length was 21 years in both periods; interquartile range was 12-26 years in the first and 17-27 years in the second period (p = 0.002), but when further broken down into diagnostic categories, the differences were not statistically significant, with the exception of means of IHRs attributed to mental disorders (14.5 vs. 19 years, p = 0.03). (+info)Enhanced myocardial glucose use in patients with a deficiency in long-chain fatty acid transport (CD36 deficiency). (3/4783)
CD36 is a multifunctional, 88 kDa glycoprotein that is expressed on platelets and monocytes/macrophages. CD36 also has high homology with the long-chain fatty acid (LFA) transporter in the myocardium. Although platelet and monocyte CD36 levels can indicate a CD36 deficiency, they cannot predict specific clinical manifestations in the myocardium of a given person. We examined the hypothesis that a deficiency in LFA transport augments myocardial glucose uptake in patients with a type I CD36 deficiency. METHODS: Seven fasting patients with a type I CD36 deficiency and 9 controls were assessed by cardiac radionuclide imaging using beta-methyl-p-iodophenyl-pentadecanoic acid (BMIPP) as a LFA tracer and by PET with 18F-fluorodeoxyglucose (FDG). RESULTS: None of the patients with a CD36 deficiency showed myocardial uptake of BMIPP. The percentage dose uptake of BMIPP in these subjects was significantly lower than that in normal controls (1.31+/-0.24 versus 2.90+/-0.2; P < 0.005). PET studies revealed that myocardial FDG accumulation was substantially increased in patients with a CD36 deficiency. Quantitative analysis showed that the percentage dose uptake of FDG in patients with a CD36 deficiency was significantly higher than that in normal controls (1.28+/-0.35 versus 0.43+/-0.22; P< 0.01). CONCLUSION: CD36 functions as a major myocardial LFA transporter and its absence may cause a compensatory upregulation of myocardial glucose uptake. (+info)Cardiocutaneous fistula. (4/4783)
Infection of the Teflon pledgets on the heart suture line after left ventricular aneurysm repair, presenting late with a fistulous tract connecting the heart with the skin (cardiocutaneous fistula) is an uncommon but potentially serious condition. The case is reported of a 73 year old man who developed a cardiocutaneous fistula extending through the left hemidiaphragm and draining at the abdominal wall, which developed six years after left ventricular aneurysmectomy. Following radiographic evaluation, which established the diagnosis, the Teflon pledgets and fistulous tract were successfully surgically removed. Prompt diagnosis depends on a high index of suspicion. Eradication of infection requires excision of infected material, which must be planned on an individual basis. (+info)Usefulness of fractional flow reserve to predict clinical outcome after balloon angioplasty. (5/4783)
BACKGROUND: After regular coronary balloon angioplasty, it would be helpful to identify those patients who have a low cardiac event rate. Coronary angiography alone is not sensitive enough for that purpose, but it has been suggested that the combination of optimal angiographic and optimal functional results indicates a low restenosis chance. Pressure-derived myocardial fractional flow reserve (FFR) is an index of the functional severity of the residual epicardial lesion and could be useful for that purpose. METHODS AND RESULTS: In 60 consecutive patients with single-vessel disease, balloon angioplasty was performed by use of a pressure instead of a regular guide wire. Both quantitative coronary angiography (QCA) and measurement of FFR were performed 15 minutes after the procedure. A successful angioplasty result, defined as a residual diameter stenosis (DS) <50%, was achieved in 58 patients. In these patients, DS and FFR, measured 15 minutes after PTCA, were analyzed in relation to clinical outcome. In those 26 patients with both optimal angiographic (residual DS by QCA /=0.90) results, event-free survival rates at 6, 12, and 24 months were 92+/-5%, 92+/-5%, and 88+/-6%, respectively, versus 72+/-8%, 69+/-8%, and 59+/-9%, respectively, in the remaining 32 patients in whom the angiographic or functional result or both were suboptimal (P=0.047, P=0.028, and P=0.014, respectively). CONCLUSIONS: In patients with a residual DS /=0.90, clinical outcome up to 2 years is excellent. Therefore, there is a complementary value of coronary angiography and coronary pressure measurement in the evaluation of PTCA result. (+info)An unusual family of benign "X" linked muscular dystrophy with cardiac involvement. (6/4783)
A family of benign X-linked muscular dystrophy is described. Two of the 3 affected members appear quite representative of Becker's dystrophy. A third shows no pseudohypertrophy, only gross atrophy, affecting proximal and distal muscles and also shows early onset contractures and electrocardiographic abnormalities and is in these ways much more representative of the variety described by Emery and Dreifuss (1966). Two of the cases have distinctly abnormal electrocardiograms with extensive and deep Q waves and abnormal R/S ratios and VI. Both these have shown progression of electrocardiographic abnormalities during a 2-year follow-up. The family is reported to document this very unusual occurrence. (+info)Intensive care management of stroke patients. (7/4783)
Two hundred eighty patients were admitted to an intensive care stroke unit over a one-year period. Subsequent investigation indicated that only 199 of these patients actually had cerebral ischemic or hemorrhagic lesions, 10 had other cerebrovascular lesions, and the remaining 71 patients had unrelated diseases, predominantly seizures. Detailed analysis of 103 stroke patients revealed an overall incidence of 59% hypertension, and 72% had hypertensive, ischemic or valvular heart disease. Fifty percent of the patients had various cardiac arrhythmias, some of which were responsible for the acute cerebrovascular lesion. Fourteen patients died during the acute phase, 11 from apparently irreversible cerebral selling, mainly due to cerebral hemorrhage. Secondary complications such as pneumonia, pulmonary embolism, pressure sores and urinary infection were almost nonexistent, but beneficial effects on the primary cerebral lesions were more difficult to demonstrate. (+info)Digitalis. (8/4783)
Cardiac glycosides have played a prominent role in the therapy of congestive heart failure since William Withering codified their use in his late 18th century monograph on the efficacy of the leaves of the common foxglove plant (Digitalis purpurea). Despite their widespread acceptance into medical practice in the ensuing 200 years, both the efficacy and the safety of this class of drugs continue to be a topic of debate. Moreover, despite the fact that the molecular target for the cardiac glycosides, the alpha-subunit of sarcolemmal Na+K+-ATPase (or sodium pump) found on most eukaryotic cell membranes, has been known for several decades, it remains controversial whether the sympatholytic or positive inotropic effects of these agents is the mechanism most relevant to relief of heart failure symptoms in humans with systolic ventricular dysfunction. Herein, we review the molecular and clinical pharmacology of this venerable class of drugs, as well as the manifestations of digitalis toxicity and their treatment. We also review in some detail recent clinical trials designed to examine the efficacy of these drugs in heart failure, with a focus on the Digoxin Investigation Group data set. Although, in our opinion, the data on balance warrant the continued use of these drugs for the treatment of symptoms of heart failure in patients already receiving contemporary multidrug therapy for this disease, the use of digitalis preparations will inevitably decline with the maturation of newer pharmacotherapies. (+info)
Have mild regurgitation. Want to use slendertone. Is this okay to use if I have cardiac problems?
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Congenital Heart Disease
Referrals - Prenatal diagnosis of congenital heart diseaseCongestiveHealthMutationsTreatmentsPatientsConditionsValveMetabolicRisksProgressionStructuralHealthyBloodCongestive Heart FSymptomsIschemicSkipPreventionDiabetesCardiovascular diseases2019ChestValvularMyocardial infarctionRheumatic DiseasesAffectsArrhythmiaAtrialChronicDeathsStrokesComplicationsCongenital heart disease inSearchAdult congenital heart dPerson'sAbnormal heartAdultsPeopleDiagnosisPalpitationsHypertensive heart dHigh cholesterolAmerican Heart AssocValve diseaseDevelopment of coronary arteryOccursBlood vessels of the heartRisk for heart diseasePulmonaryResearchersHealthyErectile DysfunctionTreatmentsCardiologyArtery DiseaseAtherosclerosis and heartSignsAortic
Congestive1
- Cardiovascular conditions such as congestive heart disease are extremely prevalent in many Western and Westernised countries, and may also be on the rise in developing countries. (evolving-science.com)
Health1
- therefore, somehow making it more widespread in the short term may have a positive effect on the global health burden that is cardiovascular disease. (evolving-science.com)
Mutations1
- A research team from the University of Pennsylvania set out to investigate the therapeutic potential of a strategy centred on mimicking these mutations to reduce heart disease risk in patients. (evolving-science.com)
Treatments1
- Therefore, ANGPTL3 is the newest biochemical target of interest for scientists interested in heart disease treatments. (evolving-science.com)
Patients1
- These factors are in turn related to certain genes that may determine the overall susceptibility to heart disease in some patients. (evolving-science.com)
Conditions1
- Conditions such as heart disease are strongly associated with arterial damage and obstruction with cholesterol plaques and the biochemical factors that may contribute to them. (evolving-science.com)
Valve3
- According to Structural Heart Disease Expert In India in this disease, our heart valve is leaky either due to irregularity of shape or by other functioning. (drravindersinghrao.com)
- But the major catheter process is adopted to block the hole and repairing the heart valve. (drravindersinghrao.com)
- Where it inflate the balloon which stops the hole inside the wall of the heart and valve. (drravindersinghrao.com)
Metabolic1
- These genes are responsible for processes such as the synthesis of 'pro-heart disease' lipoproteins (large molecules composed of amino acids and fats that may determine how well this fat is used as metabolic energy) or the pathologies that lead to cholesterol plaque formation. (evolving-science.com)
Risks1
- ANGPTL3 , which codes for angiopoietin-like protein 3, has been observed to be associated with the formation of low-density lipoproteins, which have been observed to be more likely to increase heart disease risks. (evolving-science.com)
Progression1
- These include gene-editing, which could modify the biochemical basis for heart disease risk or progression. (evolving-science.com)
Structural5
- As the word describe Structural Heart Disease which means a defect in the heart structure this is generally by birth. (drravindersinghrao.com)
- And sometimes a hole inside the heart by birth can also be the structural heart disease. (drravindersinghrao.com)
- Structural heart disease is very unpredictable some times they show symptoms or sometimes make it difficult to live. (drravindersinghrao.com)
- Treatment of structural heart disease involves various kinds of treatment according to the type of disease. (drravindersinghrao.com)
- As the word describe Structural Heart Disease which means a defect in the heart structure this. (drravindersinghrao.com)
Healthy1
- Lifestyle (physical activity, heart healthy/low sodium diet, etc. (wordpress.com)
Blood1
- In addition, ANGPTL3 may also be related to the increased concentrations of trigylcerides (partially-digested dietary fats) in the blood, another risk factor of cardiovascular diseases. (evolving-science.com)
Congestive Heart F6
- A pacemaker may also treat fainting spells (syncope), congestive heart failure, and hypertrophic cardiomyopathy. (webmd.com)
- They are a mainstay treatment for congestive heart failure. (webmd.com)
- In mild cases there may be no symptoms, while in advanced cases, valvular heart disease may lead to congestive heart failure and other complications. (hopkinsmedicine.org)
- Many of the symptoms are similar to those associated with congestive heart failure, such as shortness of breath and wheezing after limited physical exertion and swelling of the feet, ankles, hands or abdomen (edema). (hopkinsmedicine.org)
- Hypertensive, coronary, congenital, and other forms of cardiovascular disease, either singly or in combination, can lead to a state in which the heart is unable to expel sufficient blood for the metabolic demands of the body, ultimately resulting in congestive heart failure . (factmonster.com)
- 427.8) Other specified cardiac dysrhythmias (427.81) Sick sinus syndrome (427.89) Sinus bradycardia, NOS (427.9) Cardiac dysrhythmia unspecified Gallop rhythm (428) Heart failure (428.0) Congestive heart failure unspecified (428.1) Left heart failure Pulmonary edema, acute (428.2) Systolic heart failure (428.3) Diastolic heart failure (428.4) Heart failure, combined, unspec. (wikipedia.org)
Symptoms41
- Learn how to lower your chance for heart disease, ask your health provider questions about heart health, and make sure you know the symptoms of a heart attack. (cdc.gov)
- The symptoms of heart attack can be different in women vs. men, and are often misunderstood - even by some physicians. (goredforwomen.org)
- Only about 50% of African-American women are aware of the signs and symptoms of a heart attack. (goredforwomen.org)
- One day, he experienced what appeared to be textbook symptoms of a heart attack. (lymedisease.org)
- In addition to heart problems, other bizarre symptoms come and go. (lymedisease.org)
- The symptoms and signs of hypertensive heart disease will depend on whether or not it is accompanied by heart failure . (wikipedia.org)
- Women are more likely than men to have atypical heart attack symptoms such as neck and shoulder pain , abdominal pain , nausea , vomiting , fatigue , and shortness of breath . (medicinenet.com)
- Silent heart attacks (heart attacks with little or no symptoms) are more common among women than among men. (medicinenet.com)
- Because of the atypical nature of symptoms and the occasional difficulties in diagnosing heart attacks in women, women are less likely to receive aggressive thrombolytic therapy or coronary angioplasty , and are more likely to receive it later than men. (medicinenet.com)
- For more, please read the Heart Attack Symptoms - Different In Women! (medicinenet.com)
- Some people who have diabetic heart disease have no signs or symptoms of heart disease. (medlineplus.gov)
- Others have some or all of the symptoms of heart disease. (medlineplus.gov)
- You can also experience other symptoms, such as heart palpitations and unusual breathlessness. (www.nhs.uk)
- Coronary heart disease cannot be cured but treatment can help manage the symptoms and reduce the chances of problems, such as heart attacks. (www.nhs.uk)
- Valve disease symptoms can occur suddenly, depending upon how quickly the disease develops. (hopkinsmedicine.org)
- If it advances slowly, then your heart may adjust and you may not notice the onset of any symptoms easily. (hopkinsmedicine.org)
- Additionally, the severity of the symptoms does not necessarily correlate to the severity of the valve disease. (hopkinsmedicine.org)
- That is, you could have no symptoms at all, but have severe valve disease. (hopkinsmedicine.org)
- Diagnosis Just like any other heart disease, diabetic heart disease is diagnosed based on symptoms, medical and family histories, a physical examination and several tests. (issuu.com)
- Learn about heart disease, heart attack symptoms, and the signs of a heart attack. (medicinenet.com)
- Intermittent fasting (eating fewer meals a day or not eating occasionally) may reverse inflammation and improve symptoms of some diseases, such as asthma. (aarp.org)
- All these symptoms occur because the heart must work too hard to keep adequate blood flowing to the different parts of the body, like a mechanical pump with one or more valves leaking or too tight. (news-medical.net)
- These are symptoms of very late disease and require intensive management. (news-medical.net)
- After years of considering the symptoms of the disease to be the same for men and women, the medical industry has noted differences and begun to create awareness. (bellaonline.com)
- If you are concerned about any symptoms or looking for great resources regarding heart disease, go to womenheart.org. (bellaonline.com)
- In retrospect, Cox had no idea that her nausea and headache were heart attack symptoms. (tennessean.com)
- Meeting with a doctor can also provide clarity on any symptoms that could be heart related but that, as in Cox's case, may be masquerading as something else. (tennessean.com)
- Things like fatigue, weakness, shortness of breath, difficulty breathing at night or chest and stomach symptoms are often misconstrued as heart burn or dyspepsia, but could suggest heart disease," he says. (tennessean.com)
- The first stage of Lyme disease is the acute stage - the rash or the flu-like symptoms," Aucott told Healthline. (healthline.com)
- Knowing the symptoms of early-stage Lyme disease can help prevent later complications. (healthline.com)
- However, many individuals suffer heart attacks and have few, if any symptoms, especially women and diabetics. (bellaonline.com)
- When asked, people frequently do not recall ever having had symptoms suspicious for a heart attack, yet when further testing is done, it turns out that they have potentially serious underlying heart disease. (bellaonline.com)
- He denied any history of heart disease or recalling any symptoms consistent with a prior heart attack. (bellaonline.com)
- When portions of the heart muscle do not receive sufficient flow, symptoms such as shortness of breath, marked fatigue or chest pains may occur. (healthcentral.com)
- Such symptoms should not be ignored, especially in people at risk of heart disease by virtue of strong family history, habitual use of certain drugs (such as cocaine), and age (all people over the age of 40). (healthcentral.com)
- In the early stages of the disease, there are generally no symptoms. (healthcentral.com)
- Angina usually subsides quickly with rest, but over time, symptoms arise with less exertion, occur more frequently, have greater duration, and may eventually lead to a heart attack. (healthcentral.com)
- Once a person has symptoms of cardiovascular disease, damage has already been done to the body. (prweb.com)
- Once you get symptoms, more extensive and sometimes invasive tests, such as angiogram are needed to confirm the result and assess severity of damage to the arteries of the heart or elsewhere. (prweb.com)
- If you have a heart attack, you are more likely to survive if you know the signs and symptoms , call 9-1-1 right away, and get to a hospital quickly. (virginia.gov)
- If you have symptoms or risk factors for heart disease, be clear about them with your doctor. (uhc.com)
Ischemic9
- According to ICD-10, hypertensive heart disease (I11), and its subcategories: hypertensive heart disease with heart failure (I11.0) and hypertensive heart disease without heart failure (I11.9) are distinguished from chronic rheumatic heart diseases (I05-I09), other forms of heart disease (I30-I52) and ischemic heart diseases (I20-I25). (wikipedia.org)
- However, since high blood pressure is a risk factor for atherosclerosis and ischemic heart disease , death rates from hypertensive heart disease provide an incomplete measure of the burden of disease due to high blood pressure. (wikipedia.org)
- Ye S. (2013) Ischemic Heart Disease. (springer.com)
- 10. Date of download: 9/30/2015 From: Diagnosis of Stable Ischemic Heart Disease: Summary of a Clinical Practice Guideline From the American College of Physicians/American College of Cardiology Foundation/American Heart Association/American Association for Thoracic Surgery/Preventive Cardiovascular Nurses Association/Society of Thoracic SurgeonsAnn Intern Med. (slideshare.net)
- Coronary heart disease , also called coronary artery disease or ischemic heart disease , disease characterized by an inadequate supply of oxygen-rich blood to the heart muscle (myocardium) because of narrowing or blocking of a coronary artery by fatty plaques ( see atherosclerosis ). (britannica.com)
- Mortality From Ischemic Heart Disease. (nih.gov)
- Background Ischemic heart disease (IHD) has been considered the top cause of mortality globally. (nih.gov)
- Ischemic heart disease is a heart problem caused by heart arteries that are narrowed. (heart.org)
- The lack of oxygen caused by ischemic heart disease can product chest pain, discomfort known as angina pectoris or even a heart attack. (heart.org)
Skip1
- A study published in the Journal of the American College of Cardiology found that people who skip breakfast entirely or who eat poorly to start the day are at double the risk of developing hardened arteries, which can lead to heart disease. (aarp.org)
Prevention17
- Centers for Disease Control and Prevention. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- Qi presented the study findings at the 2018 American Heart Association's Epidemiology and Prevention, Lifestyle and Cardiometabolic Health Scientific Sessions in March. (reuters.com)
- Since its inception, the American Heart Association (AHA) has lead efforts in research, prevention and treatment of heart disease, providing knowledge-based solutions for people of all ages. (goredforwomen.org)
- This report examines the partnerships developed in Million Hearts, defines the practices and approaches to cardiovascular disease prevention that occurred as a result of the program, and provides suggestions for future Million Hearts activities. (rand.org)
- According to the Centers for Disease Control and Prevention (CDC), 52% of people with diabetes have arthritis, 53% with arthritis have high blood pressure, 66% with arthritis are overweight, and about 20% of people with arthritis smoke. (arthritis.org)
- Learn how non-invasive therapies are used in the prevention and treatment of this deadly disease. (selfgrowth.com)
- In principle, all people can take these 8 simple ways towards heart disease prevention. (selfgrowth.com)
- Read about heart disease diagnostic tests, treatments, and heart disease prevention. (medicinenet.com)
- America's Heart Attack Prevention Doc and author of The Whole Heart Solution. (huffingtonpost.com)
- The findings have meaning for a majority of adults in the USA: About two-thirds are overweight or obese , according the federal Centers for Disease Control and Prevention. (usatoday.com)
- Despite the decline in deaths over time, heart disease is still the leading cause of death in the U.S., killing more than 600,000 people per year, according to the Centers for Disease Control and Prevention (CDC). (foxnews.com)
- Prevention of heart attack requires a wide ranging approach and often radical change in lifestyle. (healthy.net)
- The Centers for Disease Control and Prevention (CDC) report that between 2001 and 2016, only 1 percent of confirmed Lyme disease cases in the United States involved carditis. (healthline.com)
- But Shanthi Mendis, an expert on chronic disease prevention at the Geneva-based WHO, noted that the United States was not alone in facing an obesity epidemic, and said lifestyle choices now directly affected the health of many of the world's people. (reuters.com)
- The bottom line is that long-range prevention of coronary artery disease has got to begin in childhood, or at least adolescence," says senior researcher Dr. Henry McGill, senior scientist emeritus, at Southwest Foundation for Biomedical Research in San Antonio, Texas. (go.com)
- The Centers for Disease Control and Prevention reports that the most common type of heart disease in the United States is coronary artery disease (CAD), which can lead to heart attack. (virginia.gov)
Diabetes25
- Addiction is a chronic disease similar to other chronic diseases such as type II diabetes, cancer, and cardiovascular disease. (drugabuse.gov)
- RA patients have to have high levels of inflammation plus other heart disease risk factors, such as high blood pressure or diabetes, before inflammation increases the risk of atherosclerosis. (arthritis.org)
- According to the American Heart Association, there are six independent risk factors for heart disease that you can modify or control: smoking, high cholesterol, high blood pressure, inactivity, obesity and diabetes. (arthritis.org)
- they are increased blood cholesterol , high blood pressure , smoking cigarettes, diabetes mellitus, and a family history of coronary heart disease at a young age. (medicinenet.com)
- If you have diabetes or pre-diabetes you have an increased risk for heart disease. (medlineplus.gov)
- Diabetes by itself puts you at risk for heart disease. (medlineplus.gov)
- Diabetic Heart Disease Diabetic heart disease refers to heart disease that develops in people who have diabetes. (issuu.com)
- People with diabetes are 2 to 4 times more likely to develop cardiovascular disease than people without diabetes. (issuu.com)
- Although it is more common in the elderly, serious cardiovascular disease may develop in people with diabetes who are even younger than 30. (issuu.com)
- examples include high blood pressure , elevated blood cholesterol levels, smoking , obesity , diabetes , unhealthy diet, and family history of early coronary heart disease (i.e., diagnosed in middle age). (britannica.com)
- Type 2 diabetes is linked to obesity and is also associated with increased risk of heart disease. (news-medical.net)
- A campaign has been launched to educate people with type 2 diabetes about heart disease and what they can do to reduce their risk. (healthline.com)
- There is a link between diabetes and heart disease and the results can be deadly. (healthline.com)
- So, the American Diabetes Association (ADA) and the American Heart Association (AHA) have partnered to both educate and motivate people with type 2 diabetes to minimize their risk for cardiovascular disease. (healthline.com)
- The new, multi-year awareness and education initiative is called Know Diabetes by Heart . (healthline.com)
- According to the AHA , adults with diabetes are two to four times more likely to die from cardiovascular disease than those without diabetes. (healthline.com)
- The public health impact and growing threat of diabetes and cardiovascular disease are too significant for any one organization to tackle alone," said Nancy Brown, chief executive officer of the American Heart Association in a press release . (healthline.com)
- Our collaboration with the American Diabetes Association and industry supporters is crucial for developing meaningful solutions and offering practical tools and information that can help those living with type 2 diabetes find inspiration and take action toward improving their health and decreasing their risk of heart disease," Brown added. (healthline.com)
- The connection between type 2 diabetes and heart disease begins with high glucose (blood sugar) levels. (healthline.com)
- The heart and blood vessels, stomach, nerves … as well as muscle and reproductive systems are all at risk with diabetes," Joy Cornthwaite, RD, diabetes educator at UTHealth/UT Physicians in Houston, Texas, told Healthline. (healthline.com)
- As someone living with type 2 diabetes, I empathize with the denial, worry, fear and even frustration that can accompany a diabetes diagnosis and the daily management of the disease," said Tracey D. Brown, chief executive officer of the ADA, in a press release . (healthline.com)
- Over the years, other research has linked coffee consumption with lower rates of heart attack, liver cancer and diabetes . (newscientist.com)
- Comparable data for heart failure, which is a different process not due to clogging of blood vessels but due to the heart wearing out as a result of diabetes, obesity and underlying high blood pressure, has not been coming down as fast, Barr told Reuters Health by phone. (foxnews.com)
- Two-thirds of U.S. adults and nearly one in three children are overweight or obese - a condition that increases their risk for diabetes, heart disease and other chronic illnesses. (reuters.com)
- If you have high cholesterol, high blood pressure, or diabetes, there are steps you can take to lower your risk for heart disease. (virginia.gov)
Cardiovascular diseases5
- An estimated 44 million women in the U.S. are affected by cardiovascular diseases. (goredforwomen.org)
- Cardiovascular diseases are the leading cause of death for Hispanic women, killing nearly 21,000 annually. (goredforwomen.org)
- Cardiovascular diseases are the leading cause of death for African-American women, killing over 48,000 annually. (goredforwomen.org)
- In an exclusive interview with EURACTIV journalists Henriette Jacobsen and Evan Lamos, EU Commissioner for Health Tonio Borg said that fighting cardiovascular diseases should be 'higher on the political agenda', as it is the number one killer disease in the EU. (euractiv.com)
- Many physicians probably recognize that patients with cardiovascular disease are at risk of kidney disease progression, but to my knowledge, this is the first study quantifying the contribution of different cardiovascular diseases to the development of kidney failure," co-author Kunihiro Matsushita, of Johns Hopkins Bloomberg School of Public Health, said in a press release. (upi.com)
20191
Chest8
- Women have a higher occurrence than men of chest pain that is not caused by heart disease , for example chest pain from spasm of the esophagus . (medicinenet.com)
- They also help ease chest pain caused by blocked blood vessels of the heart. (webmd.com)
- An AED, an automatic external defibrillator, is a device used to administer an electric shock through the chest wall to the heart. (webmd.com)
- No single test can diagnose diabetic heart disease, so your doctor may recommend some of the following tests: blood tests, chest X-ray, electrocardiogram (ECG), echocardiography, stress test and urinalysis. (issuu.com)
- If the deprivation is insufficient to cause infarction (death of a section of heart muscle), the effect may be angina pectoris (pain or discomfort in the chest). (britannica.com)
- A lead is imbedded in the inner wall from the right side of your heart and the ICD is generally placed in your upper left chest area below your collar bone. (medhelp.org)
- Most people are aware of chest discomfort on the left side of the chest which can be associated with shortness of breath, jaw pain, left arm pain, nausea, dizziness and sweating," says Dr. Sharmin Basher, assistant professor of medicine, general and preventive cardiology at the Vanderbilt Heart and Vascular Institute. (tennessean.com)
- Coronary heart disease - a condition which can lead to a myocardial infarction ( heart attack ) that may be fatal, or angina pectoris (chest pains). (conservapedia.com)
Valvular16
- Valvular heart disease is when any valve in the heart has damage or is diseased. (cdc.gov)
- About 2.5% of the U.S. population has valvular heart disease, but it is more common in older adults. (cdc.gov)
- About 13% of people born before 1943 have valvular heart disease. (cdc.gov)
- In 2017, there were 3,046 deaths due to rheumatic valvular heart disease and 24,811 deaths due to non-rheumatic valvular heart disease in the United States. (cdc.gov)
- Valvular heart disease is characterized by damage to or a defect in one of the four heart valves: the mitral, aortic, tricuspid or pulmonary. (hopkinsmedicine.org)
- The mitral and aortic valves are the ones most frequently affected by valvular heart disease. (hopkinsmedicine.org)
- In valvular heart disease, the valves become too narrow and hardened (stenotic) to open fully, or are unable to close completely (incompetent). (hopkinsmedicine.org)
- The severity of valvular heart disease varies. (hopkinsmedicine.org)
- Rheumatic fever may cause valvular heart disease. (hopkinsmedicine.org)
- Bacterial endocarditis , an infection of the inner lining of the heart muscle and heart valves (endocardium), is a cause of valvular heart disease. (hopkinsmedicine.org)
- Methysergide, a medication used to treat migraine headaches, and some diet drugs may promote valvular heart disease. (hopkinsmedicine.org)
- Radiation therapy (used to treat cancer) may be associated with valvular heart disease. (hopkinsmedicine.org)
- Timely administration of antibiotics may prevent the development of rheumatic fever which can cause valvular heart disease. (hopkinsmedicine.org)
- During your examination, the doctor listens for distinctive heart sounds, known as heart murmurs, which indicate valvular heart disease. (hopkinsmedicine.org)
- Researchers say the technique may be "ideal" for studying blood flow abnormalities in other forms of heart disease, including hypertension, valvular heart disease and cardiomypathies. (bbc.co.uk)
- Valvular heart disease - disease of one or more of the valves of the heart. (conservapedia.com)
Myocardial infarction3
- If the oxygen depletion is extreme, the effect may be a myocardial infarction ( heart attack ). (britannica.com)
- A heart attack, also called a myocardial infarction, occurs when a section of the heart muscle dies or gets damaged because of reduced blood supply. (virginia.gov)
- Too much plaque will reduce the flow of blood to the heart muscle, which eventually gives out in a heart attack ( myocardial infarction ). (conservapedia.com)
Rheumatic Diseases2
- As for people with OA, a study of 8,000 people in Finland, published in the Annals of Rheumatic Diseases , found that men with OA in even a single finger joint were 42% more likely to die of cardiovascular disease than those who didn't have OA. (arthritis.org)
- Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. (elsevier.com)
Affects8
- This brief fact sheet describes how heart disease affects minority women. (healthfinder.gov)
- Dr. Emily Senay joins Rene Syler to discuss how heart disease affects women differently than men, and what women should do to prevent it. (cbsnews.com)
- Lisa shows you how you can reduce your dependence on medication and achieve good heart health with food and physical activity, through blog posts such as the health benefits of folic acid for the heart, how high salt intake affects more than blood pressure, and steps to counteract metabolic syndrome through weight loss, physical activity, and following a Mediterranean diet . (medicalnewstoday.com)
- This will also help manage your weight which also affects your heart condition. (wikihow.com)
- The biggest misconception is that heart disease only affects people who have obvious risk factors, like obesity, smoking or high cholesterol," Houle says. (tennessean.com)
- Heart failure disproportionately affects low-income Americans and African Americans, he said. (foxnews.com)
- The main manifestation of Lyme carditis is it affects the electrical system of the heart," said Aucott. (healthline.com)
- It is an autosomal dominant disorder that affects bones in the arms and hands (the upper limbs) and may also cause heart problems. (wikipedia.org)
Arrhythmia3
- Cardioversion For many people with heart disease, drugs alone won't turn an arrhythmia into a normal heart rhythm. (webmd.com)
- Sudden arrhythmia death syndromes (SADS) are genetic heart rhythm abnormalities conditions that can cause sudden death in young, apparently healthy people - who are undiagnosed. (healthfinder.gov)
- An arrhythmia is an abnormal heart rhythm which may cause problems if untreated. (healthfinder.gov)
Atrial3
- A child may even "grow out" of some of the simpler heart defects, such as patent ductus arteriosus (PDA) or atrial septal defect (ASD), as these defects may resolve on their own as the child grows. (cincinnatichildrens.org)
- Another problem is atrial fibrillation or the lack of a regular atrial beat, as a result of atrial dilation which interferes with the proper function of the heart pacemaker in the left atrial wall. (news-medical.net)
- The syndrome includes an absent radial bone in the arms, an atrial septal defect, and a first degree heart block. (wikipedia.org)
Chronic5
- Evidence from adoption and twin studies demonstrate that addiction, like other chronic diseases, is a heritable disorder and that genes play a role in vulnerability to addiction. (drugabuse.gov)
- Chronic coronary artery disease. (springer.com)
- Learn about finding doctors and clinics specializing in pediatric cardiomyopathy, a chronic disease of the heart muscle. (healthfinder.gov)
- But when it gets out of control (and sticks around longer than needed), chronic inflammation has been linked to numerous conditions, including heart disease, Alzheimer's disease and some cancers. (aarp.org)
- Borg also announced that he is launching an EU summit on chronic diseases at the beginning of next year. (euractiv.com)
Deaths16
- In 2013 hypertensive heart disease resulted in 1.07 million deaths as compared with 630,000 deaths in 1990. (wikipedia.org)
- More than 50 percent of premature deaths in people with rheumatoid arthritis result from cardiovascular disease, according to a 2011 review of 24 mortality studies published in Nature Reviews Rheumatology . (arthritis.org)
- SCD is responsible for half of all heart disease deaths. (webmd.com)
- Heart disease is the cause of approximately half the deaths in the United States each year. (factmonster.com)
- Exposure to tobacco smoke contributes to about 34,000 premature heart disease deaths a year, according to the American Heart Association. (medicinenet.com)
- However, her team noticed an even more dramatic effect in deaths caused by cardiovascular disease. (newscientist.com)
- Dr. Mercola states that frequent sauna bathing will reduce the risk of heart-related deaths. (archive.org)
- The researchers used data on heart disease deaths among people age 35 and over in the U.S. collected in two year intervals, between 1973 and 2010, from more than 3,000 counties of the 48 contiguous states. (foxnews.com)
- Every county saw a decline in heart disease deaths. (foxnews.com)
- The average decline across the U.S. was 61 percent, but some counties only saw a decline of 9 percent while others cut heart disease deaths by 83 percent. (foxnews.com)
- At the beginning of the study, heart disease deaths were most common in the Northeast through Appalachia and into the Midwest. (foxnews.com)
- Since the 1970s, national attention on the dangers of cigarette smoking and uncontrolled high blood pressure has led to a significant decline in deaths from coronary heart disease and heart attack, but 'heart disease' includes other conditions which have not decreased as much, said Dr. Donald A. Barr of Stanford University School of Medicine in California, who wrote an editorial accompanying the new study. (foxnews.com)
- There were still meaningful declines in heart disease deaths in the South, Casper noted. (foxnews.com)
- Heart disease-related deaths are largely preventable, and with targeted public health efforts, it's possible to alleviate much of the heavy burden of this disease and close the geographic gap in declining heart disease death rates,' Casper said. (foxnews.com)
- A study by British scientists found that around half of those deaths could be averted if people ate healthier food and quit smoking, and experts warned there was no room for complacency when it came to heart health risks. (reuters.com)
- the age-adjusted annual death rate from heart disease plunged from 559 deaths (per 100,000) in 1960 to 240 in 2002, and it continues to fall. (conservapedia.com)
Strokes2
- As expected, overweight and obese people had more strokes and heart disease and were more likely to have high blood pressure and unhealthy cholesterol and blood glucose numbers. (usatoday.com)
- Once they had accounted for participants' age, race and other risk factors for heart disease, the researchers found those with the highest levels of PFOA were about twice as likely to report heart problems or strokes compared to those with low chemical levels. (reuters.com)
Complications6
- Hypertensive heart disease includes a number of complications of high blood pressure that affect the heart . (wikipedia.org)
- Lyme disease can go on to cause heart and other complications, but preventing tick bites and early treatment of infection can reduce those risks. (healthline.com)
- While carditis is treatable, Aucott said the more important public health issue is trying to recognize and treat Lyme disease earlier before complications like carditis occur. (healthline.com)
- People can also reduce their risk of Lyme disease and its complications by avoiding being bitten by a tick in the first place. (healthline.com)
- Each year about 785,000 Americans will have a first heart attack, once of the serious complications caused by CHD. (healthcentral.com)
- Choosing healthful meal and snack options can help you avoid heart disease and its complications. (virginia.gov)
Congenital heart disease in1
- With the rising incidence of congenital heart disease in adults, an understanding of the patient's physiology and anesthetic implications is critical for anesthesiologists. (springer.com)
Search1
- I am an integrative cardiologist and I search the medical literature for therapies for heart disease that compliment or replace conventional practice. (huffingtonpost.com)
Adult congenital heart d1
- Anesthesia and adult congenital heart disease. (springer.com)
Person's5
- Heart Transplant A person's diseased heart is replaced with a healthy donor's heart. (webmd.com)
- When a person's heart stops, blood stops circulating throughout the body. (webmd.com)
- Consumption of What is Unlawful Corrupts the Hearts and Prevents Supplications from Being Answered There is clearly a strong relationship between the soundness or corruption of a person's heart and his food and earnings. (islamweb.net)
- A person's heart becomes corrupt when he earns what is prohibited and dares to eat of it. (islamweb.net)
- Currently, doctors estimate a person's statistical chance of developing heart disease by looking at individual factors such as whether they smoke, their family history, weight, blood cholesterol and blood pressure. (prweb.com)
Abnormal heart4
- Except for his abnormal heart rhythm, called heart block. (lymedisease.org)
- Implantable Cardioverter Defibrillators (ICD) An ICD, or implantable cardioverter defibrillator, can treat abnormal heart rhythms. (webmd.com)
- Antiarrhythmics These drugs treat abnormal heart rhythms caused by irregular electrical activity of your heart. (webmd.com)
- Cialis should not be taken by men with angina or abnormal heart beats not controlled by medical treatment, or by men whose angina is triggered by sex. (netdoctor.co.uk)
Adults11
- In addition to other established associations between dental health and risk of disease, our findings suggest that middle-aged adults who have lost two or more teeth in recent past could be at increased risk for cardiovascular disease," Dr. Lu Qi of Tulane University in New Orleans said in a statement. (reuters.com)
- Among adults with 25 to 32 natural teeth at the beginning of the study, those who lost two or more teeth during follow-up had a 23 percent increased risk of coronary heart disease compared with those who didn't lose any teeth. (reuters.com)
- Adults with fewer than 17 natural teeth (vs. 25 to 32 natural teeth) at the outset were 25 percent more likely to develop coronary heart disease. (reuters.com)
- Those risks appear to culminate in another formidable figure: According to a National Health Interview Survey, one in four adults with any form of arthritis also has heart disease. (arthritis.org)
- Anesthetic implications of adults with congenital heart disease. (springer.com)
- ACC/AHA 2008 guidelines for the management of adults with congenital heart disease. (springer.com)
- The Congenital Heart Information Network offers this listing of local, regional, and national support groups throughout the globe for families and adults with congenital heart disease. (healthfinder.gov)
- This did not mean the children had heart disease, she clarified, merely that some of them exhibited risk factors associated with its development in adults. (telegraph.co.uk)
- Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. (elsevier.com)
- Our specialists care for adolescents and adults with congenital heart disease and value open and ongoing communication with referring pediatricians, internists and primary cardiologists. (massgeneral.org)
- For their research, Matsushita and his team examined data on 9,047 American adults who did not have signs of heart disease when they enrolled in a community-based study, following their health status for a median period of 17.5 years. (upi.com)
People26
- Imaging studies have shown evidence of tissue malfunction in the brains of those with addiction, and in the hearts of people with heart disease. (drugabuse.gov)
- People with gout also have a higher risk of heart attack and death from cardiovascular and coronary heart disease. (arthritis.org)
- Nitrates These are meds that treat angina in people with coronary artery disease. (webmd.com)
- That compared with only 29% of healthy people who had gum disease. (latimes.com)
- Although most of these episodes, called arrhythmias, are harmless and happen in healthy people free of heart disease, sometimes, however, arrhythmias can be serious or even fatal. (healthfinder.gov)
- Attempting to avoid calories and fats to prevent heart disease, people often eliminate nuts from their diet, even though they contain healthy fats and a large source of Mg. (medicalnewstoday.com)
- People with gum disease often have the same risk factors for heart disease. (medicinenet.com)
- Cardiovascular disease kills more people than any other disease and account for the largest share in health expenditure. (news-medical.net)
- People who drink 14 or more glasses of wine or beer a week have the lowest risk of a heart attack, according to new research. (decanter.com)
- In these people, consumption of 14 or more drinks a week was associated with the lowest risk of coronary heart disease," say the researchers from the Beth Israel Deaconess Medical Centre in Boston. (decanter.com)
- People who drink up to 30 units of alcohol a week are less likely to die of a heart attack than abstainers. (decanter.com)
- It found that people who consumed several cups of coffee every day were less likely to die of heart disease than those who shied away from the stuff. (newscientist.com)
- In 2006, a team of Canadian researchers discovered that people with a mutation in a gene involved in metabolising caffeine had higher rates of heart attack than people without the mutation. (newscientist.com)
- The mutation, a deletion of 25 letters of genetic code from the heart protein gene MYBPC3, is virtually restricted to people from the Indian subcontinent. (redorbit.com)
- The mutation was discovered five years ago in two Indian families with cardiomyopathy, but its significance only became apparent after almost 1500 people from many parts of India, some with heart disease and some without, were studied. (redorbit.com)
- While any problems with the heart - fatal or otherwise - are concerning, experts say that people shouldn't be overly alarmed about this condition, even people who live in tick-heavy states such as Vermont. (healthline.com)
- Coronary artery disease, the leading cause of death in America, claims the lives of hundreds of thousands of people each year. (bellaonline.com)
- They found that almost 200,000 lives could be saved if certain heart risk factors were cut, even modestly, in particular, Capewell said, "if people ate healthier food and stopped smoking. (reuters.com)
- That's because it's not clear what came first for people in the study - the higher chemical levels or the heart disease. (reuters.com)
- His team used data from 1,216 people in a national survey who had blood tests and answered questions about their history of a range of diseases in 1999 through 2003. (reuters.com)
- But it's still not clear from the findings that PFOA caused heart problems, or even that PFOA levels were higher than normal before people got sick. (reuters.com)
- High triglycerides signal uncontrolled blood glucose levels in diabetics, and they can signal coronary artery disease in some people. (cnn.com)
- About 250,000 people will die from their heart attack before they reach the hospital. (conservapedia.com)
- For people who survive a heart attack, about 20% of women and 16% of men will have another during the next four years. (conservapedia.com)
- In all, kidney disease kills more people -- an estimated 47,000 annually -- than breast or prostate cancer, per agency estimates. (upi.com)
- The study took place in Spain, where scientists randomly assigned 7,447 people who were either overweight, smokers, diabetic, or had any other heart disease risk factors to follow the Mediterranean diet or a low-fat one. (businessinsider.com)
Diagnosis4
- Each had the audacity to make a diagnosis over the phone, based purely on lab tests, and agreed unequivocally that I did not have Lyme disease. (lymedisease.org)
- Other conditions can share features with hypertensive heart disease and need to be considered in the differential diagnosis. (wikipedia.org)
- Women are more likely to encounter delays in establishing the diagnosis of heart attack than men. (medicinenet.com)
- Receiving a diagnosis of heart disease may make you feel upset, overwhelmed, and frustrated. (medicalnewstoday.com)
Palpitations1
- 3. If it is true that 'everyone' gets palpitations then how come when I ask my sister or my friends if they feel anything weird in their hearts like skipping or fluttering they always say no? (medhelp.org)
Hypertensive heart d1
- Hypertensive heart disease - heart disease caused by high blood pressure . (conservapedia.com)
High cholesterol7
- Heart disease is not caused by high cholesterol. (selfgrowth.com)
- This implies that the real culprit of cardiovascular disease has been low magnesium levels , while historically, experts have blamed a high-saturated fat diet and high cholesterol. (medicalnewstoday.com)
- This research follows on the heels of a study that came out only last week which found that young men in their 20s and 30s with high cholesterol are 2 to 3½ times more likely to die of heart disease, and have four to nine less years of life expectancy than men with healthier cholesterol levels. (go.com)
- Professor Barker said slow growth in the first year of life was probably related to poor nutrition and could make the body more prone to problems with high cholesterol - another risk factor for heart disease. (bbc.co.uk)
- High cholesterol levels in the blood are the main cause of heart disease. (medic8.com)
- Their reduced levels of oestrogen mean that they no longer receive the same protection against high cholesterol and coronary heart disease. (medic8.com)
- There are certain medical conditions which increase the risk of high cholesterol and heart disease. (medic8.com)
American Heart Assoc7
- CPR Cardiopulmonary resuscitation -- CPR -- is one link in what the American Heart Association calls the chain of survival. (webmd.com)
- Researchers at the Beth Israel Deaconess Medical Center in Boston, reported in Tuesday's issue of Circulation, the journal of the American Heart Association , that 3-D coronary magnetic resonance angiography (MRA) could soon become the standard for diagnosing coronary artery disease. (wired.com)
- The Support Network is the patient support website of the American Heart Association . (medicalnewstoday.com)
- Research published today in the Journal of the American Heart Association followed 353 men, aged 40-60, who had already had a heart attack. (decanter.com)
- The study is published in the latest issue of the Journal of the American Heart Association. (bbc.co.uk)
- A separate report from the American Heart Association (AHA) indicates that meditation may be an effective tool against heart disease when it is practiced in conjunction with proven approaches like lifestyle changes or medications. (aarp.org)
- The American Heart Association recommends keeping daily intake of cholesterol below 300 milligrams, and avoiding junk foods and fried foods. (go.com)
Valve disease7
- This is the most common cause of valve disease worldwide, but it is much less common in the United States, where most strep infections are treated early with antibiotics. (cdc.gov)
- Intravenous drug use can also lead to endocarditis and cause heart valve disease. (cdc.gov)
- Congenital heart valve disease is malformations of the heart valves, such as missing one of its leaflets. (cdc.gov)
- Valve Disease Treatment When your heart valve disease needs attention, it can be treated by traditional surgery or by balloon valvuloplasty, which doesn't require as much cutting. (webmd.com)
- However, RHD is classically a mixed valve disease, and the same valve shows different pathologic changes. (news-medical.net)
- Create healthcare diagrams like this example called Heart Valve Disease in minutes with SmartDraw. (smartdraw.com)
- Heart valve disease is a condition in which one or more of your heart valves don't work properly. (smartdraw.com)
Development of coronary artery1
- I think this technique will prove to be a valuable research tool in developing new medications to prevent the development of coronary artery disease," said Dr Schwitter. (bbc.co.uk)
Occurs6
- Learn what happens before, during and after a heart attack occurs. (medhelp.org)
- Rheumatic heart disease (RHD) is a long-term outcome of a condition called acute rheumatic fever (ARF) which typically occurs in childhood. (news-medical.net)
- Carditis occurs during stage 2, or early disseminated Lyme disease. (healthline.com)
- The lesion that occurs with Lyme disease is very characteristic," said Aucott. (healthline.com)
- Atresia occurs when a heart valve lacks an opening for blood to pass through. (smartdraw.com)
- Congenital heart disease (CHD), the most common disorder of congenital disease in humans, occurs in approximately 1% of live births [ 1 , 2 ]. (hindawi.com)
Blood vessels of the heart2
- Philips Medical Systems developed the technology, which uses magnets to display the blood vessels of the heart. (wired.com)
- Dr Juerg Schwitter, assistant professor of cardiology at the University of Zurich and author of the study, said: "With this approach we are able to assess the blood supply to the heart muscle and assess how well the blood vessels of the heart function. (bbc.co.uk)
Risk for heart disease5
- What is my risk for heart disease? (cdc.gov)
- This program informs you on risk factors, lifestyles, and eating habits to lower your risk for heart disease. (selfgrowth.com)
- Being overweight or obese can increase your risk for heart disease. (virginia.gov)
- Cigarette smoking greatly increases your risk for heart disease. (virginia.gov)
- If you do smoke, quitting will lower your risk for heart disease. (virginia.gov)
Pulmonary1
- The pulmonary valve controls the flow of blood from the heart to the lungs, and the aortic valve governs blood flow between the heart and the aorta, and thereby the blood vessels to the rest of the body. (hopkinsmedicine.org)
Researchers7
- Washington, 23 March 2001 (RFE/RL) -- A team of researchers concludes that walking at least one hour per week may lower a woman's risk of heart disease. (rferl.org)
- A test which has been used for 20 years to measure blood flow may also detect the early stages of heart disease, researchers have found. (bbc.co.uk)
- Researchers believe the technique can be used to develop new medication to fight heart disease. (bbc.co.uk)
- The researchers found that women who drank four to five cups per day were 34% less likely to die of heart disease, while men who had more than five cups a day were 44% less likely to die. (newscientist.com)
- Over the last 40 years, heart disease rates have dropped in the U.S. overall, but the changes varied widely by region, with the highest rates of the disease shifting from the Northeast to the South, researchers say. (foxnews.com)
- The researchers examined the infant and childhood growth of 4630 men of whom 357 were either admitted to hospital with coronary heart disease or who died of the disease. (bbc.co.uk)
- Researchers at the Centre for Eye Research Australia (CERA) are seeking to confirm that blood vessels in the retina at the back of the eye reflect changes in blood vessels in other parts of the body, especially the brain, kidneys and heart. (prweb.com)
Healthy18
- Healthy heart valve leaflets are able to fully open and close the valve during the heartbeat, but diseased valves might not fully open and close. (cdc.gov)
- Eat healthy, stay active, be smoke-free, and limit alcohol use to lower your chance for heart disease. (cdc.gov)
- What is a heart-healthy eating plan for me? (cdc.gov)
- A heart-healthy lifestyle is also advised to reduce the risks of high blood pressure, atherosclerosis and heart attack. (hopkinsmedicine.org)
- Heart healthy foods and exercise are key components to any cardiovascular program. (selfgrowth.com)
- How to Lower Cholesterol - Natural Ways to Lower Blood Pressure - The Best Way to Lose Weight Receive expert guidance via free and paid programs for a healthy heart and longer life naturally. (selfgrowth.com)
- Exercise , a balanced diet and avoiding high-risk activities like smoking are some of the best ways to keep your heart healthy," he said in a hospital news release. (medicinenet.com)
- Cathy Elton's blog What Would Cathy Eat focuses specifically on heart-healthy food. (medicalnewstoday.com)
- She developed heart-healthy vegetarian recipes that were still spicy, satisfying, adventurous, and tasty. (medicalnewstoday.com)
- Cathy even managed to continue eating apple pie by replacing lard with heart-healthy oils. (medicalnewstoday.com)
- Is a low-fat diet really that heart healthy after all? (medhelp.org)
- Fish oil, folic acid, vitamin C. Find out if these supplements are heart-healthy or overhyped. (medhelp.org)
- Lately, the Mediterranean diet - which incorporates heart-healthy foods typically used in M. (medhelp.org)
- While some heart conditions cannot be "reversed" per se, healthy lifestyle in combination with the expertise of ones' doctor and effectively manage and stabilize or slow the progression of heart disease. (wikihow.com)
- Eat a heart-healthy breakfast. (wikihow.com)
- A new study says that eating a healthy breakfast could help you avoid heart trouble down the road. (aarp.org)
- f you stick with a "healthy diet" you can lower your risk of heart disease. (healthy.net)
- Healthy blood fat levels are key to fighting heart disease. (cnn.com)
Erectile Dysfunction7
- Erectile Dysfunction: Harbinger of Heart Disease? (medscape.com)
- Erectile dysfunction is something that we haven't talked about much in the cardiology office, but we are finding that it is a harbinger of coronary artery diseases. (medscape.com)
- For instance, if you are a 70-year-old man with erectile dysfunction, your risk for coronary disease is increased one to 1.4 times, but if you are a 40-year-old man with erectile dysfunction your risk for coronary disease is 40 to 50 times higher. (medscape.com)
- Steve, just so I am hearing you correctly, you said that for a younger patient in his 40s, erectile dysfunction portends a risk 40 to 50 times higher than usual for coronary disease? (medscape.com)
- Heart disease is also associated with various factors that increase the likelihood of erectile dysfunction (ED) and make treatment more difficult. (netdoctor.co.uk)
- Not all treatments for erectile dysfunction are suitable for men with heart disease. (netdoctor.co.uk)
- Erectile dysfunction commonly exists in men with heart disease, but all treatments for ED are stated to be unsuitable for men with conditions that make sex inadvisable, such as severe heart conditions. (netdoctor.co.uk)
Treatments4
- Treatments include medications to treat heart damage or to lower your blood glucose ( blood sugar ), blood pressure, and cholesterol. (medlineplus.gov)
- Diabetics are disadvantaged by lower success rate in some heart disease treatments, such as coronary artery bypass grafting and angioplasty. (issuu.com)
- The problem is not the actual treatments, but whether sexual activity might put too much strain on the heart. (netdoctor.co.uk)
- In this context, physicians should be aware of cardiovascular disease as an important risk condition, and thereby minimize treatments that are toxic to the kidneys in such individuals," Junichi Ishigami, also aresearcher at Johns Hopkins, said. (upi.com)
Cardiology1
- Heart disease kills hundreds of thousands of Americans each year, but many of these conditions are preventable," said researcher Dr. David Slotwiner, chief of the division of cardiology at NewYork-Presbyterian Queens. (medicinenet.com)
Artery Disease8
- In fact, a 50-year-old woman faces a 46% risk of developing CAD and a 31% risk of dying from coronary artery disease . (medicinenet.com)
- An electrocardiogram , also called an ECG or EKG, to measure the electrical activity of the heart, regularity of heartbeats, thickening of heart muscle (hypertrophy) and heart-muscle damage from coronary artery disease. (hopkinsmedicine.org)
- Blood vessel disease also is called peripheral vascular disease or artery disease. (healthfinder.gov)
- Coronary Artery Disease (CAD), or atherosclerosis, involves the hardening of the blood vessels by fatty deposits called plaque. (healthfinder.gov)
- Another mummy with coronary artery disease, Princess Ahmose-Meryet-Amon, lived between 1580 and 1550 BC and is the oldest known case of human heart disease. (livescience.com)
- Is CABG the preferred method of revascularization in multivessel coronary artery disease? (cmaj.ca)
- Coronary heart disease (CHD)-also sometimes called coronary artery disease-is the most common form of cardiovascular disease, a group of disorders that involve the heart and blood vessels. (healthcentral.com)
- David H. Leake tells about the patented cure he learned about that reversed and eliminated his own coronary artery disease. (youtube.com)
Atherosclerosis and heart1
- High blood cholesterol directly raises the risk of atherosclerosis and heart disease. (news-medical.net)
Signs3
- There are numerous signs of a sickness of the heart. (islamweb.net)
- Houle agrees, noting that early signs of heart disease can actually mimic other conditions. (tennessean.com)
- For this, and other reasons, it is imperative that women know what to look for should they develop signs concerning for heart disease. (bellaonline.com)
Aortic3
- Any valve in the heart can become diseased, but the aortic valve is most commonly affected. (cdc.gov)
- As of July 2013[update], known heart-hand syndromes include Holt-Oram syndrome, Berk-Tabatznik syndrome, heart-hand syndrome type 3, brachydactyly-long thumb syndrome, patent ductus arteriosus-bicuspid aortic valve syndrome and heart hand syndrome, Slovenian type. (wikipedia.org)
- Holt-Oram syndrome, Brachydactyly-long thumb syndrome, Patent ductus arteriosus-bicuspid aortic valve syndrome and Heart-hand syndrome, Slovenian type are known to be autosomally dominant disorders. (wikipedia.org)
