A species of halophilic archaea found in the Dead Sea.
A species of halophilic archaea found in the Mediterranean Sea. It produces bacteriocins active against a range of other halobacteria.
An order of extremely halophilic archaea, in the kingdom EURYARCHAEOTA. They occur ubiquitously in nature where the salt concentration is high, and are chemoorganotrophic, using amino acids or carbohydrates as a carbon source.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in archaea.
Ribonucleic acid in archaea having regulatory and catalytic roles as well as involvement in protein synthesis.
Proteins found in any species of archaeon.
A family of extremely halophilic archaea found in environments with high salt concentrations, such as salt lakes, evaporated brines, or salted fish. Halobacteriaceae are either obligate aerobes or facultative anaerobes and are divided into at least twenty-six genera including: HALOARCULA; HALOBACTERIUM; HALOCOCCUS; HALOFERAX; HALORUBRUM; NATRONOBACTERIUM; and NATRONOCOCCUS.
The functional genetic units of ARCHAEA.
One of the three domains of life (the others being BACTERIA and Eukarya), formerly called Archaebacteria under the taxon Bacteria, but now considered separate and distinct. They are characterized by: (1) the presence of characteristic tRNAs and ribosomal RNAs; (2) the absence of peptidoglycan cell walls; (3) the presence of ether-linked lipids built from branched-chain subunits; and (4) their occurrence in unusual habitats. While archaea resemble bacteria in morphology and genomic organization, they resemble eukarya in their method of genomic replication. The domain contains at least four kingdoms: CRENARCHAEOTA; EURYARCHAEOTA; NANOARCHAEOTA; and KORARCHAEOTA.
Deoxyribonucleic acid that makes up the genetic material of archaea.
Structures within the nucleus of archaeal cells consisting of or containing DNA, which carry genetic information essential to the cell.
The genetic complement of an archaeal organism (ARCHAEA) as represented in its DNA.
A genus of HALOBACTERIACEAE distinguished from other genera in the family by the presence of specific derivatives of TGD-2 polar lipids. Haloarcula are found in neutral saline environments such as salt lakes, marine salterns, and saline soils.
A genus of extremely halophilic HALOBACTERIACEAE which are chemoheterotropic and strictly aerobic. They are found in neutral saline environments such as salt lakes (especially the Dead Sea) and marine salterns.
A trans-carotenoid pigment widely distributed in nature. The compound is used as an oral suntanning agent and as a food and drug coloring agent. Oral ingestion of the compound causes canthaxanthin retinopathy.
A species of halophilic archaea found in salt lakes. Some strains form a PURPLE MEMBRANE under anaerobic conditions.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
An important enzyme in the glyoxylic acid cycle which reversibly catalyzes the synthesis of L-malate from acetyl-CoA and glyoxylate. This enzyme was formerly listed as EC 4.1.3.2.
A genus of HALOBACTERIACEAE whose growth requires a high concentration of salt. Binary fission is by constriction.
A glucose dehydrogenase that catalyzes the oxidation of beta-D-glucose to form D-glucono-1,5-lactone, using NAD as well as NADP as a coenzyme.
The small subunit of archaeal RIBOSOMES. It is composed of the 16S RIBOSOMAL RNA and about 28 different RIBOSOMAL PROTEINS.
Phosphoric acid esters of dolichol.
A transfer RNA which is specific for carrying tryptophan to sites on the ribosomes in preparation for protein synthesis.
A ubiquitous sodium salt that is commonly used to season food.
Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.
Fatty acid biopolymers that are biosynthesized by microbial polyhydroxyalkanoate synthase enzymes. They are being investigated for use as biodegradable polyesters.
A transfer RNA which is specific for carrying proline to sites on the ribosomes in preparation for protein synthesis.
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.
Degree of saltiness, which is largely the OSMOLAR CONCENTRATION of SODIUM CHLORIDE plus any other SALTS present. It is an ecological factor of considerable importance, influencing the types of organisms that live in an ENVIRONMENT.
I'm sorry for any confusion, but the term "Oklahoma" is a geographical location and not a medical condition or term, therefore it doesn't have a medical definition. It is a state in the South Central region of the United States.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Magnesium chloride. An inorganic compound consisting of one magnesium and two chloride ions. The compound is used in medicine as a source of magnesium ions, which are essential for many cellular activities. It has also been used as a cathartic and in alloys.
The process by which a DNA molecule is duplicated.

The ShBle resistance determinant from Streptoalloteichus hindustanus is expressed in Haloferax volcanii and confers resistance to bleomycin. (1/22)

We have designed a gene cassette for expression of the bleomycin-resistance protein from Streptoalloteichus hindustanus (ShBle) in the extremely halophilic archaeon Haloferax volcanii, and shown that transformed haloarchaea are resistant to bleomycin. Recombinant ShBle was purified by a one-step affinity-chromatography procedure as a correctly folded, dimeric protein. ShBle thus provides a useful haloarchaeal selectable marker and represents the first non-halophilic and soluble heterologous protein to be expressed in the Haloarchaea.  (+info)

Puromycin-rRNA interaction sites at the peptidyl transferase center. (2/22)

The binding site of puromycin was probed chemically in the peptidyl-transferase center of ribosomes from Escherichia coli and of puromycin-hypersensitive ribosomes from the archaeon Haloferax gibbonsii. Several nucleotides of the 23S rRNAs showed altered chemical reactivities in the presence of puromycin. They include A2439, G2505, and G2553 for E. coli, and G2058, A2503, G2505, and G2553 for Hf. gibbonsii (using the E. coli numbering system). Reproducible enhanced reactivities were also observed at A508 and A1579 within domains I and III, respectively, of E. coli 23S rRNA. In further experiments, puromycin was shown to produce a major reduction in the UV-induced crosslinking of deacylated-(2N3A76)tRNA to U2506 within the P' site of E. coli ribosomes. Moreover, it strongly stimulated the putative UV-induced crosslink between a streptogramin B drug and m2A2503/psi2504 at an adjacent site in E. coli 23S rRNA. These data strongly support the concept that puromycin, along with other peptidyl-transferase antibiotics, in particular the streptogramin B drugs, bind to an RNA structural motif that contains several conserved and accessible base moieties of the peptidyl transferase loop region. This streptogramin motif is also likely to provide binding sites for the 3' termini of the acceptor and donor tRNAs. In contrast, the effects at A508 and A1579, which are located at the exit site of the peptide channel, are likely to be caused by a structural effect transmitted along the peptide channel.  (+info)

Use of a halobacterial bgaH reporter gene to analyse the regulation of gene expression in halophilic archaea. (3/22)

The bgaH reading frame encoding a beta-galactosidase of 'Haloferax alicantei' was used as a reporter gene to investigate three different promoter regions derived from gvpA genes of Haloferax mediterranei (mc-gvpA) and Halobacterium salinarum (c-gvpA and p-gvpA) in Haloferax volcanii transformants. The fusion of bgaH at the start codon of each gvpA reading frame (A1-bgaH fusion genes) caused translational problems in some cases. Transformants containing constructs with fusions further downstream in the gvpA reading frame (A-bgaH) produced beta-galactosidase, and colonies on agar plates turned blue when sprayed with X-Gal. The beta-galactosidase activities quantified by standard ONPG assays correlated well with the mRNA data determined with transformants containing the respective gvpA genes: the cA-bgaH fusion gene was completely inactive, the mcA-bgaH transformants showed low amounts of products, whereas the pA-bgaH fusion gene was constitutively expressed in the respective transformants. The transcription of each A-bgaH gene was activated by the homologous transcriptional activator protein GvpE. The cGvpE, pGvpE and mcGvpE proteins were able to activate the promoter of pA-bgaH and mcA-bgaH, whereas the promoter of cA-bgaH was only activated by cGvpE. Among the three GvpE proteins tested, cGvpE appeared to be the strongest transcriptional activator.  (+info)

Post-translational modification of the S-layer glycoprotein occurs following translocation across the plasma membrane of the haloarchaeon Haloferax volcanii. (4/22)

The halophilic archaeon Haloferax volcanii is surrounded by a protein shell solely comprised of the S-layer glycoprotein. While the gene sequence and glycosylation pattern of the protein and indeed the three-dimensional structure of the surface layer formed by the protein have been described, little is known of the biosynthesis of the S-layer glycoprotein. In the following, pulse-chase radiolabeling and cell-fractionation studies were employed to reveal that newly synthesized S-layer glycoprotein undergoes a maturation step following translocation of the protein across the plasma membrane. The processing step, detected as an increase in the apparent molecular mass of the S-layer glycoprotein, is unaffected by inhibition of protein synthesis and is apparently unrelated to glycosylation of the protein. Maturation requires the presence of magnesium ions, involved in membrane association of the S-layer glycoprotein, and results in increased hydrophobicity of the protein as revealed by enhanced detergent binding. Thus, along with protein glycosylation, additional post-translational modifications apparently occur on the external face of the haloarchaeal plasma membrane, the proposed topological homologue of the lumenal face of the eukaryal endoplasmic reticulum membrane.  (+info)

Haloferax alexandrinus sp. nov., an extremely halophilic canthaxanthin-producing archaeon from a solar saltern in Alexandria (Egypt). (5/22)

An extremely halophilic red micro-organism designated strain TM(T) was isolated from a solar saltern in Alexandria, Egypt. The micro-organism stains gram-negative, is very pleomorphic, non-motile and strictly aerobic and requires at least 10 g NaCl l(-1) for growth. The growth optimum is 250 g NaCl l(-1). Growth is also observed over a wide range of MgSO4 concentrations (10-40 g l(-1)). Aerobic reduction of nitrate without gas production was detected. Cells grew aerobically in a minimal salts medium containing ammonium chloride and glucose. Strain TM(T) produced acid from fructose, glucose, rhamnose, maltose and glycerol. The G+C content of the DNA was 59.5+/-0.3 mol %. On the basis of polar lipid analysis, the isolate belonged to the genus Haloferax. Analysis of the 16S rDNA sequence showed the highest similarity (>99%) to be to the type strain Haloferax volcanii. Although the spectrum of antibiotic susceptibility was similar to that of validly described species of the genus Haloferax, the strain could be distinguished from them by its different response to josamycin and rifampicin. Strain TM(T) is unique within the genus Haloferax in producing canthaxanthin. Comparative analysis of phenotypic properties and DNA-DNA hybridization between strain TM(T) and Haloferax species supported the conclusion that TM(T) is a novel species within this genus, for which the name Haloferax alexandrinus sp. nov. is proposed. The type strain is TM(T) (= JCM 10717T = IFO 16590T).  (+info)

Lipid modification of proteins in Archaea: attachment of a mevalonic acid-based lipid moiety to the surface-layer glycoprotein of Haloferax volcanii follows protein translocation. (6/22)

Once the newly synthesized surface (S)-layer glycoprotein of the halophilic archaeaon Haloferax volcanii has traversed the plasma membrane, the protein undergoes a membrane-related, Mg(2+)-dependent maturation event, revealed as an increase in the apparent molecular mass and hydrophobicity of the protein. To test whether lipid modification of the S-layer glycoprotein could explain these observations, H. volcanii cells were incubated with a radiolabelled precursor of isoprene, [(3)H]mevalonic acid. In Archaea, isoprenoids serve as the major hydrophobic component of archaeal membrane lipids and have been shown to modify other haloarchaeal S-layer glycoproteins, although little is known of the mechanism, site or purpose of such modification. In the present study we report that the H. volcanii S-layer glycoprotein is modified by a derivative of mevalonic acid and that maturation of the protein was prevented upon treatment with mevinolin (lovastatin), an inhibitor of mevalonic acid biosynthesis. These findings suggest that lipid modification of S-layer glycoproteins is a general property of halophilic archaea and, like S-layer glycoprotein glycosylation, lipid-modification of the S-layer glycoproteins takes place on the external cell surface, i.e. following protein translocation across the membrane.  (+info)

Novel polar lipids of halophilic eubacterium Planococcus H8 and archaeon Haloferax volcanii. (7/22)

As part of a study to identify novel lipids with immune adjuvant activity, a structural comparison was made between the polar lipids from two halophiles, an archaeon Haloferax volcanii and a eubacterium Planococcus H8. H. volcanii polar lipid extracts consisted of 44% archaetidylglycerol methylphosphate, 35% archaetidylglycerol, 4.7% of archaeal cardiolipin, 2.5% archaetidic acid, and 14% sulfated glycolipids 1 and 2. Nuclear magnetic resonance (NMR) and Fast atom bombardment mass spectrometry (FAB MS) data determined the glycolipids to be 6-HSO(3)-D-Man(p)-alpha1-2-D-Glc(p)-alpha1,1-[sn-2,3-di-O-phytanylglycerol] and a novel glycocardiolipin 6'-HSO(3)-D-Man(p)-alpha1-2-D-Glc(p)-alpha1,1-[sn-2,3-di-O-phytanylglycerol]-6-[p hospho-sn-2,3-di-O-phytanylglycerol]. The polar lipids of Planococcus H8 consisted of 49% saturated phosphatidylglycerol and cardiolipin (9:1, w/w), and surprisingly 51% of the photosynthetic membrane lipid sulfoquinovosyldiacylglycerol (SQDG). This study documents archaeal cardiolipin and a novel glycocardiolipin in H. volcanii (lacking purple membrane), and is the first report of SQDG in a non-photosynthetic, halophilic bacterium.  (+info)

Combined use of cultivation-dependent and cultivation-independent methods indicates that members of most haloarchaeal groups in an Australian crystallizer pond are cultivable. (8/22)

Haloarchaea are the dominant microbial flora in hypersaline waters with near-saturating salt levels. The haloarchaeal diversity of an Australian saltern crystallizer pond was examined by use of a library of PCR-amplified 16S rRNA genes and by cultivation. High viable counts (10(6) CFU/ml) were obtained on solid media. Long incubation times (> or =8 weeks) appeared to be more important than the medium composition for maximizing viable counts and diversity. Of 66 isolates examined, all belonged to the family Halobacteriaceae, including members related to species of the genera Haloferax, Halorubrum, and Natronomonas. In addition, isolates belonging to a novel group (the ADL group), previously detected only as 16S rRNA genes in an Antarctic hypersaline lake (Deep Lake), were cultivated for the first time. The 16S rRNA gene library identified the following five main groups: Halorubrum groups 1 and 2 (49%), the SHOW (square haloarchaea of Walsby) group (33%), the ADL group (16%), and the Natronomonas group (2%). There were two significant differences between the organisms detected in cultivation and 16S rRNA sequence results. Firstly, Haloferax spp. were frequently isolated on plates (15% of all isolates) but were not detected in the 16S rRNA sequences. Control experiments indicated that a bias against Haloferax sequences in the generation of the 16S rRNA gene library was unlikely, suggesting that Haloferax spp. readily form colonies, even though they were not a dominant group. Secondly, while the 16S rRNA gene library identified the SHOW group as a major component of the microbial community, no isolates of this group were obtained. This inability to culture members of the SHOW group remains an outstanding problem in studying the ecology of hypersaline environments.  (+info)

I apologize for any confusion, but "Haloferax volcanii" is not a medical term or concept. It is actually a species of archaea (single-celled microorganisms) that is commonly found in extremely salty environments, such as salt lakes and salt mines. The name "Haloferax volcanii" refers to the fact that this organism is halophilic (salt-loving) and was first isolated from a volcanic site.

Here is a brief scientific definition of "Haloferax volcanii":

Haloferax volcanii is a species of halophilic archaea belonging to the family Haloferacaceae. It is a rod-shaped, motile organism that is commonly found in hypersaline environments such as salt lakes and salt mines. The optimum growth temperature for H. volcanii is around 45°C, and it can tolerate a wide range of salinities (up to 3 M NaCl). It has a relatively large genome (around 4 Mb) that contains many genes involved in DNA repair and stress response, making it well-adapted to life in extreme environments. H. volcanii is also known for its ability to form stable triparental mating structures, which are used in genetic studies of archaea.

'Haloferax mediterranei' is not a medical term, but a species name in the field of microbiology. It refers to a type of archaea (a single-celled microorganism) that is halophilic, meaning it thrives in high-salt environments. The species was first isolated from a solar saltern in Alicante, Spain, and is known for its ability to produce and degrade various biopolymers, making it of interest in biotechnological applications. It's not directly related to human health or medicine, but understanding the diversity and characteristics of different microorganisms can have broader implications for fields such as environmental science and infectious disease research.

Halobacteriales is an order of archaea, a domain of single-celled microorganisms. These organisms are often referred to as extremophiles because they thrive in environments with high salt concentrations, such as salt lakes, salt pans, and solar salterns. In fact, many members of Halobacteriales require salt concentrations of at least 15-20% (w/v) to grow optimally.

Members of this order are characterized by their ability to produce a pigment called bacteriorhodopsin, which is used in a process called phototrophy to generate energy from light. This is unusual because most archaea and bacteria rely on chemosynthesis for energy production. Halobacteriales also have unique cell membranes that contain ether lipids, making them more resistant to extreme conditions.

Some notable members of Halobacteriales include Halobacterium salinarum and Haloferax volcanii, which are commonly used in laboratory research due to their ability to grow quickly and easily under controlled conditions. These organisms have contributed significantly to our understanding of archaeal biology and evolution.

Gene expression regulation in archaea refers to the complex cellular processes that control the transcription and translation of genes into functional proteins. This regulation is crucial for the survival and adaptation of archaea to various environmental conditions.

Archaea, like bacteria and eukaryotes, use a variety of mechanisms to regulate gene expression, including:

1. Transcriptional regulation: This involves controlling the initiation, elongation, and termination of transcription by RNA polymerase. Archaea have a unique transcription machinery that is more similar to eukaryotic RNA polymerases than bacterial ones. Transcriptional regulators, such as activators and repressors, bind to specific DNA sequences near the promoter region to modulate transcription.
2. Post-transcriptional regulation: This includes processes like RNA processing, modification, and degradation that affect mRNA stability and translation efficiency. Archaea have a variety of RNA-binding proteins and small non-coding RNAs (sRNAs) that play crucial roles in post-transcriptional regulation.
3. Translational regulation: This involves controlling the initiation, elongation, and termination of translation by ribosomes. Archaea use a unique set of translation initiation factors and tRNA modifications to regulate protein synthesis.
4. Post-translational regulation: This includes processes like protein folding, modification, and degradation that affect protein stability and function. Archaea have various chaperones, proteases, and modifying enzymes that participate in post-translational regulation.

Overall, gene expression regulation in archaea is a highly dynamic and coordinated process involving multiple layers of control to ensure proper gene expression under changing environmental conditions.

Archaeal RNA refers to the Ribonucleic acid (RNA) molecules that are present in archaea, which are a domain of single-celled microorganisms. RNA is a nucleic acid that plays a crucial role in various biological processes, such as protein synthesis, gene expression, and regulation of cellular activities.

Archaeal RNAs can be categorized into different types based on their functions, including:

1. Messenger RNA (mRNA): It carries genetic information from DNA to the ribosome, where it is translated into proteins.
2. Transfer RNA (tRNA): It helps in translating the genetic code present in mRNA into specific amino acids during protein synthesis.
3. Ribosomal RNA (rRNA): It is a structural and functional component of ribosomes, where protein synthesis occurs.
4. Non-coding RNA: These are RNAs that do not code for proteins but have regulatory functions in gene expression and other cellular processes.

Archaeal RNAs share similarities with both bacterial and eukaryotic RNAs, but they also possess unique features that distinguish them from the other two domains of life. For example, archaeal rRNAs contain unique sequence motifs and secondary structures that are not found in bacteria or eukaryotes. These differences suggest that archaeal RNAs have evolved to adapt to the extreme environments where many archaea live.

Overall, understanding the structure, function, and evolution of archaeal RNA is essential for gaining insights into the biology of these unique microorganisms and their roles in various cellular processes.

Archaeal proteins are proteins that are encoded by the genes found in archaea, a domain of single-celled microorganisms. These proteins are crucial for various cellular functions and structures in archaea, which are adapted to survive in extreme environments such as high temperatures, high salt concentrations, and low pH levels.

Archaeal proteins share similarities with both bacterial and eukaryotic proteins, but they also have unique features that distinguish them from each other. For example, many archaeal proteins contain unusual amino acids or modifications that are not commonly found in other organisms. Additionally, the three-dimensional structures of some archaeal proteins are distinct from their bacterial and eukaryotic counterparts.

Studying archaeal proteins is important for understanding the biology of these unique organisms and for gaining insights into the evolution of life on Earth. Furthermore, because some archaea can survive in extreme environments, their proteins may have properties that make them useful in industrial and medical applications.

Halobacteriaceae is a family of Archaea, a domain of single-celled organisms. These microorganisms are extremely halophilic, meaning they require high concentrations of salt to survive and grow. They are typically found in environments such as salt lakes, salt pans, and other saline habitats.

The cells of Halobacteriaceae are usually rod-shaped or irregularly shaped, and they can form pink, red, or purple colorations in their natural environments due to the presence of carotenoid pigments and retinal-based proteins called bacteriorhodopsins. These proteins function as light-driven proton pumps, allowing the cells to generate a proton gradient and create ATP, which is their primary energy source.

Halobacteriaceae are also known for their ability to survive in extreme conditions, such as high temperatures, radiation, and desiccation. They have evolved unique adaptations to cope with these harsh environments, making them a fascinating subject of study in the field of extremophile microbiology.

I'm happy to help! However, I believe there might be a slight mistake in your question. "Archaeal" is not a term used to describe genes but rather a group of single-celled organisms that are classified as archaea.

Archaea are one of the three domains of life, along with bacteria and eukaryotes (which include plants, animals, and fungi). Archaea are unique because they share characteristics with both bacteria and eukaryotes, but they also have many features that are distinctly their own. For example, archaea have a different cell membrane structure than bacteria and eukaryotes, which allows them to thrive in extreme environments such as hot springs, salt mines, and deep-sea vents.

Genes, on the other hand, are segments of DNA that contain the instructions for making proteins or performing other important functions in an organism's cells. All living organisms, including archaea, have genes that are passed down from generation to generation. Archaeal genes are made up of the same four nucleotides (A, T, C, and G) as bacterial and eukaryotic genes, and they code for proteins and RNA molecules that are essential for the survival and reproduction of archaea.

So, to summarize, there is no specific definition for "Archaeal genes" because "archaeal" is not a term used to describe genes. However, we can say that archaeal genes are segments of DNA that contain the instructions for making proteins and performing other important functions in archaea.

Archaea are a domain of single-celled microorganisms that lack membrane-bound nuclei and other organelles. They are characterized by the unique structure of their cell walls, membranes, and ribosomes. Archaea were originally classified as bacteria, but they differ from bacteria in several key ways, including their genetic material and metabolic processes.

Archaea can be found in a wide range of environments, including some of the most extreme habitats on Earth, such as hot springs, deep-sea vents, and highly saline lakes. Some species of Archaea are able to survive in the absence of oxygen, while others require oxygen to live.

Archaea play important roles in global nutrient cycles, including the nitrogen cycle and the carbon cycle. They are also being studied for their potential role in industrial processes, such as the production of biofuels and the treatment of wastewater.

Archaeal DNA refers to the genetic material present in archaea, a domain of single-celled microorganisms lacking a nucleus. Like bacteria, archaea have a single circular chromosome that contains their genetic information. However, archaeal DNA is significantly different from bacterial and eukaryotic DNA in terms of its structure and composition.

Archaeal DNA is characterized by the presence of unique modifications such as methylation patterns, which help distinguish it from other types of DNA. Additionally, archaea have a distinct set of genes involved in DNA replication, repair, and recombination, many of which are more similar to those found in eukaryotes than bacteria.

One notable feature of archaeal DNA is its resistance to environmental stressors such as extreme temperatures, pH levels, and salt concentrations. This allows archaea to thrive in some of the most inhospitable environments on Earth, including hydrothermal vents, acidic hot springs, and highly saline lakes.

Overall, the study of archaeal DNA has provided valuable insights into the evolutionary history of life on Earth and the unique adaptations that allow these organisms to survive in extreme conditions.

Archaeal chromosomes refer to the genetic material present in Archaea, a domain of single-celled microorganisms. Like bacteria and eukaryotes, Archaea have their genetic material organized into a single circular chromosome, which is typically smaller than bacterial chromosomes. The archaeal chromosome contains all the genetic information necessary for the organism's survival, including genes coding for proteins, RNA molecules, and regulatory elements that control gene expression.

Archaeal chromosomes are structurally similar to bacterial chromosomes, with a histone-like protein called histone-like protein A (HLP) that helps compact the DNA into a more condensed form. However, archaeal chromosomes also share some features with eukaryotic chromosomes, such as the presence of nucleosome-like structures and the use of similar mechanisms for DNA replication and repair.

Overall, archaeal chromosomes are an important area of study in molecular biology, as they provide insights into the evolution and diversity of life on Earth.

An archaeal genome refers to the complete set of genetic material or DNA present in an archaea, a single-celled microorganism that is found in some of the most extreme environments on Earth. The genome of an archaea contains all the information necessary for its survival, including the instructions for building proteins and other essential molecules, as well as the regulatory elements that control gene expression.

Archaeal genomes are typically circular in structure and range in size from about 0.5 to over 5 million base pairs. They contain genes that are similar to those found in bacteria and eukaryotes, as well as unique genes that are specific to archaea. The study of archaeal genomes has provided valuable insights into the evolutionary history of life on Earth and has helped scientists understand the adaptations that allow these organisms to thrive in such harsh environments.

"Haloarcula" is a genus of archaea, which are single-celled microorganisms that lack a nucleus and other membrane-bound organelles. This genus belongs to the family Halobacteriaceae and is characterized by its ability to thrive in extremely salty environments, such as salt lakes and salt mines. The cells of Haloarcula species are typically pink or red due to the presence of carotenoid pigments, which help protect the organisms from high levels of solar radiation.

Haloarcula species are heterotrophic, meaning they obtain energy by consuming organic matter. They are also aerobic, requiring oxygen to grow and metabolize nutrients. Like other members of the domain Archaea, Haloarcula species have a unique cell wall structure and genetic material that is distinct from bacteria and eukaryotes.

It's important to note that "Haloarcula" is a medical definition in the sense that it refers to a specific genus of archaea that can have implications for human health, particularly in the context of environmental health and microbial ecology. However, Haloarcula species are not typically associated with human diseases or infections.

"Haloferax" is a genus of halophilic archaea, which are organisms that thrive in highly saline environments. Members of this genus are typically found in salt lakes, salt pans, and other hypersaline habitats. They are characterized by their ability to grow optimally at sodium chloride concentrations of around 2-3 M (10-15% w/v), which is roughly ten times the salinity of seawater.

The name "Haloferax" comes from the Greek words "halos," meaning salt, and "phorax," meaning carrier or bearer, reflecting their ability to thrive in high-salt environments. These archaea are known for their versatility in terms of energy metabolism, as they can grow either aerobically or anaerobically using various electron donors and acceptors. They also play a significant role in the global nitrogen cycle, as some species are capable of denitrification and nitrate reduction.

It is important to note that "Haloferax" is not a medical term per se but rather a taxonomic designation for a group of archaea with specific ecological and physiological characteristics. However, understanding the biology and ecology of these organisms can contribute to our broader knowledge of microbial diversity, evolution, and adaptation to extreme environments.

Canthaxanthin is a type of carotenoid, which is a class of pigments that are naturally occurring in certain plants and animals. It has a yellow-to-reddish color and is used as a food additive (coloring agent) and as a dietary supplement. In the medical field, canthaxanthin has been studied for its potential effects on skin conditions such as sun sensitivity and keratosis; however, its use in these contexts is not widely accepted or recommended due to limited evidence of effectiveness and potential safety concerns.

"Halobacterium salinarum" is not a medical term, but a scientific name for a type of archaea (single-celled microorganism) that is commonly found in extremely salty environments, such as salt lakes and solar salterns. It is often used as a model organism in research related to archaea and extremophiles.

Here's a brief scientific definition:

"Halobacterium salinarum" is a species of halophilic archaea belonging to the family Halobacteriaceae. It is a rod-shaped, gram-negative organism that requires high salt concentrations (in the range of 15-25%) for growth and survival. This archaeon is known for its ability to produce bacteriorhodopsin, a light-driven proton pump, which gives it a purple color and allows it to generate energy through phototrophy in addition to being chemotrophic. It is also capable of forming endospores under conditions of nutrient deprivation.

Molecular sequence data refers to the specific arrangement of molecules, most commonly nucleotides in DNA or RNA, or amino acids in proteins, that make up a biological macromolecule. This data is generated through laboratory techniques such as sequencing, and provides information about the exact order of the constituent molecules. This data is crucial in various fields of biology, including genetics, evolution, and molecular biology, allowing for comparisons between different organisms, identification of genetic variations, and studies of gene function and regulation.

Malate Synthase is a key enzyme in the gluconeogenesis pathway and the glyoxylate cycle, which are present in many organisms including plants, bacteria, and parasites. The glyoxylate cycle is a variation of the citric acid cycle (Krebs cycle) that allows these organisms to convert two-carbon molecules into four-carbon molecules, bypassing steps that require oxygen.

Malate Synthase catalyzes the reaction between glyoxylate and acetyl-CoA to produce malate, a four-carbon compound. This enzyme plays a crucial role in enabling these organisms to utilize fatty acids as a carbon source for growth and energy production, particularly under conditions where oxygen is limited or absent. In humans, Malate Synthase is not typically found, but its presence can indicate certain parasitic infections or metabolic disorders.

Halobacterium is a genus of extremely halophilic archaea, which means they require a high salt concentration to grow. They are often found in salt lakes, salt pans, and other hypersaline environments. These microorganisms contain bacteriorhodopsin, a light-driven proton pump, which gives them a purple color and allows them to generate ATP using light energy, similar to photosynthesis in plants. Halobacteria are also known for their ability to survive under extreme conditions, such as high temperatures, radiation, and desiccation.

Glucose 1-Dehydrogenase (G1DH) is an enzyme that catalyzes the oxidation of β-D-glucose into D-glucono-1,5-lactone and reduces the cofactor NAD+ into NADH. This reaction plays a role in various biological processes, including glucose sensing and detoxification of reactive carbonyl species. G1DH is found in many organisms, including humans, and has several isoforms with different properties and functions.

A ribosome is a complex molecular machine found in all living cells that translates messenger RNA (mRNA) into proteins. Ribosomes are composed of two subunits: a small subunit and a large subunit. The small subunit is responsible for recognizing and binding to the mRNA, as well as decoding the genetic information it contains.

Archaeal ribosomes are similar in structure and function to eukaryotic ribosomes, but they have some distinct differences in their composition and sequence. Archaeal small ribosomal subunits, like those of bacteria, are composed of a 16S rRNA molecule and approximately 20 proteins. However, the archaeal small ribosomal subunit has a unique structure and composition that is distinct from both bacterial and eukaryotic small ribosomal subunits.

The small ribosomal subunit of Archaea is referred to as the "small, archaeal" subunit. It plays a crucial role in the initiation of protein synthesis by recognizing and binding to the Shine-Dalgarno sequence in the mRNA, which helps position the start codon for translation. The small, archaeal ribosomal subunit also contains the decoding center, where the genetic information in the mRNA is translated into a corresponding amino acid sequence during protein synthesis.

Overall, the small, archaeal ribosomal subunit is an essential component of the archaeal translational machinery, responsible for accurately and efficiently decoding genetic information and initiating the synthesis of new proteins.

Dolichol phosphates are a type of lipid molecule that play a crucial role in the process of protein glycosylation within the endoplasmic reticulum of eukaryotic cells. Glycosylation is the attachment of carbohydrate groups, or oligosaccharides, to proteins and lipids.

Dolichol phosphates consist of a long, isoprenoid hydrocarbon chain that is attached to two phosphate groups. The hydrocarbon chain can vary in length but typically contains between 10 and 20 isoprene units. These molecules serve as the anchor for the oligosaccharides during the glycosylation process.

In the first step of protein glycosylation, an oligosaccharide is synthesized on a dolichol phosphate molecule through the sequential addition of sugar residues by a series of enzymes. Once the oligosaccharide is complete, it is transferred to the target protein in a process called "oligosaccharyltransferase" (OST)-mediated transfer. This transfer results in the formation of a glycoprotein, which can then undergo further modifications as it moves through the secretory pathway.

Defects in dolichol phosphate metabolism have been linked to various genetic disorders, such as congenital disorder of glycosylation (CDG) types Ib and Id, which are characterized by abnormal protein glycosylation and a wide range of clinical manifestations, including developmental delay, neurological impairment, and multi-systemic involvement.

Transfer RNA (tRNA) for tryptophan (Trp) is a specific type of tRNA molecule that plays a crucial role in protein synthesis. In the process of translation, genetic information from messenger RNA (mRNA) is translated into a corresponding sequence of amino acids to form a protein.

Tryptophan is one of the twenty standard amino acids found in proteins. Each tRNA molecule carries a specific amino acid that corresponds to a particular codon (a sequence of three nucleotides) on the mRNA. The tRNA with tryptophan attached to it recognizes and binds to the mRNA codon UGG, which is the only codon that specifies tryptophan in the genetic code.

The tRNA molecule has a characteristic cloverleaf-like structure, composed of a stem region made up of base pairs and loop regions containing unpaired nucleotides. The anticodon loop contains the complementary sequence to the mRNA codon, allowing for specific recognition and binding. The other end of the tRNA molecule carries the amino acid, in this case tryptophan, which is attached via an ester linkage to a specific nucleotide called the 3'-end of the tRNA.

In summary, tRNA (Trp) is a key player in protein synthesis, responsible for delivering tryptophan to the ribosome during translation, where it can be incorporated into the growing polypeptide chain according to the genetic information encoded in mRNA.

Sodium Chloride is defined as the inorganic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. It is commonly known as table salt or halite, and it is used extensively in food seasoning and preservation due to its ability to enhance flavor and inhibit bacterial growth. In medicine, sodium chloride is used as a balanced electrolyte solution for rehydration and as a topical wound irrigant and antiseptic. It is also an essential component of the human body's fluid balance and nerve impulse transmission.

"Gene knockout techniques" refer to a group of biomedical research methods used in genetics and molecular biology to study the function of specific genes in an organism. These techniques involve introducing a deliberate, controlled genetic modification that results in the inactivation or "knockout" of a particular gene. This is typically achieved through various methods such as homologous recombination, where a modified version of the gene with inserted mutations is introduced into the organism's genome, replacing the original functional gene. The resulting organism, known as a "knockout mouse" or other model organisms, lacks the function of the targeted gene and can be used to study its role in biological processes, disease development, and potential therapeutic interventions.

Polyhydroxyalkanoates (PHAs) are naturally occurring, biodegradable polyesters accumulated by some bacteria as intracellular granules under conditions of limiting nutrients, typically carbon source excess and nutrient deficiency. They serve as a form of energy reserve and can be produced from renewable resources such as sugars, lipids, or organic acids. PHAs have potential applications in various fields including packaging, agriculture, pharmaceuticals, and medicine due to their biodegradability and biocompatibility.

Transfer RNA (tRNA) is a type of RNA molecule that plays a crucial role in protein synthesis, the process by which cells create proteins. In protein synthesis, tRNAs serve as adaptors, translating the genetic code present in messenger RNA (mRNA) into the corresponding amino acids required to build a protein.

tRNAs have a distinct cloverleaf-like secondary structure and a compact L-shaped tertiary structure. Each tRNA molecule contains a specific anticodon triplet nucleotide sequence that can base-pair with a complementary codon in the mRNA during translation. At the other end of the tRNA, there is an amino acid attachment site where the corresponding amino acid is covalently attached through the action of aminoacyl-tRNA synthetase enzymes.

Pro (also known as proline) is a specific amino acid that can be carried by certain tRNAs during protein synthesis. Therefore, in a medical definition context, 'RNA, Transfer, Pro' would refer to the transfer RNA molecule(s) specifically responsible for carrying and delivering proline during protein synthesis. This tRNA is typically denoted as tRNA^Pro^ or tRNA-Pro, with the superscript indicating the specific amino acid it carries.

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a bacterial defense system that confers resistance to foreign genetic elements such as plasmids and phages, by incorporating short sequences of the invasive genetic material into their own genome. These sequences are then used to recognize and destroy subsequent invasions by identical or similar genetic elements. The CRISPR system consists of two main components: the CRISPR array, which contains the repeats and spacers, and the Cas (CRISPR-associated) proteins, which provide the enzymatic activity for interference.

The CRISPR array is a stretch of DNA in the bacterial genome that contains repetitive sequences interspaced with unique sequences known as "spacers". The repeats are typically palindromic, meaning they read the same backwards as forwards, and are usually 24-48 base pairs long. The spacers are derived from the genetic material of previous invasions by viruses or plasmids, and are used to recognize and target similar sequences in future invaders.

The Cas proteins associated with the CRISPR array provide the enzymatic activity for interference. They can be classified into several different types based on their sequence and domain organization. The most well-studied type is Cas9, which uses a guide RNA derived from the CRISPR array to recognize and cleave specific sequences in the target DNA. This system has been harnessed as a powerful tool for genome editing in various organisms, including humans.

In summary, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a bacterial defense system that confers resistance to foreign genetic elements by incorporating short sequences of the invasive genetic material into their own genome and using them to recognize and destroy subsequent invasions by identical or similar genetic elements. The CRISPR system consists of two main components: the CRISPR array, which contains the repeats and spacers, and the Cas (CRISPR-associated) proteins, which provide the enzymatic activity for interference.

Salinity is not a term that has a specific medical definition. However, in general terms, salinity refers to the level of salt or sodium content in a substance, usually measured in parts per thousand (ppt). In a medical context, salinity might be discussed in relation to things like the body's fluid balance or the composition of certain bodily fluids, such as sweat or tears.

It is worth noting that in some cases, high salinity levels can have negative effects on health. For example, consuming water with very high salt content can lead to dehydration and electrolyte imbalances, which can be dangerous. Similarly, exposure to high-salinity environments (such as seawater) can cause skin irritation and other problems in some people. However, these are not direct medical definitions of salinity.

I'm sorry for any confusion, but "Oklahoma" is not a medical term or condition. It is a state in the south central region of the United States. If you have any questions about medical terminology or health-related topics, I would be happy to try and help answer them!

An amino acid sequence is the specific order of amino acids in a protein or peptide molecule, formed by the linking of the amino group (-NH2) of one amino acid to the carboxyl group (-COOH) of another amino acid through a peptide bond. The sequence is determined by the genetic code and is unique to each type of protein or peptide. It plays a crucial role in determining the three-dimensional structure and function of proteins.

Magnesium Chloride is an inorganic compound with the chemical formula MgCl2. It is a white, deliquescent solid that is highly soluble in water. Medically, magnesium chloride is used as a source of magnesium ions, which are essential for many biochemical reactions in the human body.

It can be administered orally, intravenously, or topically to treat or prevent magnesium deficiency, cardiac arrhythmias, seizures, and preterm labor. Topical application is also used as a mineral supplement and for skin care purposes due to its moisturizing properties. However, high doses of magnesium chloride can have side effects such as diarrhea, nausea, and muscle weakness, and should be used under medical supervision.

DNA replication is the biological process by which DNA makes an identical copy of itself during cell division. It is a fundamental mechanism that allows genetic information to be passed down from one generation of cells to the next. During DNA replication, each strand of the double helix serves as a template for the synthesis of a new complementary strand. This results in the creation of two identical DNA molecules. The enzymes responsible for DNA replication include helicase, which unwinds the double helix, and polymerase, which adds nucleotides to the growing strands.

... antrum, Haloferax opilio, Haloferax rutilus and Haloferax viridis were isolated from Romanian salt lakes and first ... PubMed references for Haloferax PubMed Central references for Haloferax Google Scholar references for Haloferax Haloferax at ... Haloferax litoreum, Haloferax marinisediminis and Haloferax marinum were first published in 2021, but are not accepted as of ... Haloferax marisrubri and Haloferax profundi were first published in 2020, but is not accepted as of 2022. Haloferax ...
... is a species of organism in the genus Haloferax in the Archaea. Microbiologist Benjamin Elazari Volcani ... Haloferax volcanii is noteworthy because it can be cultured without much difficulty, rare for an extremophile. H. volcanii is ... The conditions Haloferax volcanii survives in, high salinity and high radiation, are very similar to the conditions found on ... and Haloferax gen.nov". Syst. Appl. Microbiol. 8 (1-2): 89-99. doi:10.1016/s0723-2020(86)80155-2. Walsh, James C.; Angstmann, ...
"Haloferax elongans sp. nov. and Haloferax mucosum sp. nov., isolated from microbial mats from Hamelin Pool, Shark Bay, ... Haloferax elongans is a species of archaea in the family Haloferacaceae. Allen, M. A.; Goh, F.; Leuko, S.; Echigo, A.; Mizuki, ... "Species: Haloferax elongans". LPSN. 2022-12-05. Retrieved 2022-12-05. v t e (Articles with short description, Short description ...
... is a species of archaea in the family Haloferacaceae. The species was described in 2013. "Species: ... Saralov, Alexander I.; Baslerov, Roman V.; Kuznetsov, Boris B. (2013-03-23). "Haloferax chudinovii sp. nov., a halophilic ...
... is a species of archaea in the family Haloferacaceae. Asker, Dalal; Ohta, Yoshiyuki (2002-05-01). " ... "Haloferax alexandrinus sp. nov., an extremely halophilic canthaxanthin-producing archaeon from a solar saltern in Alexandria ( ...
2008). "Haloferax elongans sp. nov. and Haloferax mucosum sp. nov., isolated from microbial mats from Hamelin Pool, Shark Bay, ... When this species was discovered, the genus Haloferax comprised Haloferax volcanii, H. mediterranei, H. denitrificans, H. ... Haloferax larsenii is a gram-negative, aerobic, neutrophilic, extremely halophilic archaeon. It was named in honor of Professor ... Haloferax larsenii was isolated from a solar saltern in the Zhoushan archipelago, Zhejiang Province, China. The researchers who ...
... is a species of archaea in the family Haloferacaceae. Elshahed, Mostafa S.; Savage, Kristen N.; Oren, ... "Species: Haloferax sulfurifontis". LPSN. 2022-12-05. Retrieved 2022-12-05. v t e (Articles with short description, Short ... Aharon; Gutierrez, M. Carmen; Ventosa, Antonio; Krumholz, Lee R. (2004-11-01). "Haloferax sulfurifontis sp. nov., a halophilic ...
... is a halophilic archaeon in the family of Haloferacaceae. "LPSN - List of Prokaryotic names with Standing ...
... is a species of archaea in the family Haloferacaceae. Juez, Guadalupe; Rodriguez-Valera, F.; Ventosa, ... and Haloferax gibbonsii spec, nov., Two New Species of Extremely Halophilic Archaebacteria". Systematic and Applied ...
... is a species of archaea in the family Haloferacaceae. Page Species: Haloferax denitrificans on "LPSN - ...
"Haloferax elongans sp. nov. and Haloferax mucosum sp. nov., isolated from microbial mats from Hamelin Pool, Shark Bay, ... Haloferax mucosum is a species of archaea in the family Haloferacaceae. Allen, M. A.; Goh, F.; Leuko, S.; Echigo, A.; Mizuki, T ... "Species: Haloferax mucosum". LPSN. 2022-12-05. Retrieved 2022-12-05. v t e (Articles with short description, Short description ...
... is a species of archaea in the family Haloferacaceae. Enache, Madalin; Itoh, Takashi; Kamekura, Masahiro; ... Teodosiu, Gabriela; Dumitru, Lucia (2007-02-01). "Haloferax prahovense sp. nov., an extremely halophilic archaeon isolated from ...
Like Haloferax volcanii, it performs cell division through the formation of an FtsZ ring. Haloferax mediterranei produces a ... Haloferax mediterranei is a species of archaea in the family Haloferacaceae. Haloferax mediterranei was discovered in 1983 in ... The species was initially named Halobacterium mediterranei, then renamed Haloferax mediterranei in 1986. Haloferax mediterranei ... Haloferax mediterranei is the fastest-growing archaeon in the Halobacteriales family, with generation times as low as 1.2 hours ...
Haloferax volcanii The Halobacterium NRC-1 genome is 2,571,010 bp compiled into three circular replicons. More specifically, it ... Haloferax denitrificans Halobacterium distributum > Halorubrum distributum Halobacterium halobium > Halobacterium salinarum ... Halobacterium lacusprofundi > Halorubrum lacusprofundi Halobacterium mediterranei > Haloferax mediterranei Halobacterium ...
Gutierrez MC, Kamekura M, Holmes ML, Dyall-Smith ML, Ventosa A (December 2002). "Taxonomic characterization of Haloferax sp ... H. alicantei") strain Aa 2.2: description of Haloferax lucentensis sp. nov". Extremophiles. 6 (6): 479-83. doi:10.1007/s00792- ... Haloferax, Halogeometricum, Halococcus, Haloterrigena, Halorubrum, Haloarcula, and Halobacterium. However, the viable counts in ... "Production of halophilic proteins using Haloferax volcanii H1895 in a stirred-tank bioreactor". Applied Microbiology and ...
2016 Haloferax Torreblanca et al. 1986 Halogeometricum Montalvo-Rodriguez et al. 1998 (Halosarcina) Halogranum Cui et al. 2010 ...
Torreblanca M, Meseguer I, Rodríguez-Valera F (1989). "Halocin H6, a bacteriocin from Haloferax gibbonsii". Journal of General ... Platas G, Meseguer I, Amils R (1996). "Optimization of the production of a bacteriocin from Haloferax mediterranei Xia3". ... Platas G, Meseguer I, Amils R (2002). "Purification and biological characterization of halocin H1 from Haloferax mediterranei ... Perez, AM (2000). Growth physiology of Haloferax mediterranei R4 and purification of halocin H4. Flagstaff, Arizona: Northern ...
Halobacterium salinarum and Haloferax volcanii, model Haloarchaea. The former has a reputation in the study of DNA repair. The ...
The name Haloferacaceae is derived from the Latin term Haloferax, referring to the type genus of the family and the suffix "- ... The type genus of this family is Haloferax. Its biochemical characteristics are the same as the order Haloferacales. ... Together, Haloferacaceae refers to a family whose nomenclatural type is the genus Haloferax. As of 2021, Haloferacaceae ...
The type genus of this order is Haloferax. The name Haloferacales is derived from the Latin term Haloferax, referring to the ... Together, Haloferacales refers to an order whose nomenclatural type is the genus Haloferax. Members are halophiles and can be ...
March 2010). Friedberg I (ed.). "The complete genome sequence of Haloferax volcanii DS2, a model archaeon". PLOS ONE. 5 (3): ...
... a serine proteinase from the halophilic archaeon Haloferax mediterranei; gene cloning, expression and structural studies". ...
Likewise, the archaeon Haloferax volcanii uses recombination-dependent initiation to duplicate its genome when its endogenous ... "Genetic and physical mapping of DNA replication origins in Haloferax volcanii". PLOS Genetics. 3 (5): e77. doi:10.1371/journal. ...
"Voltage-dependent porin-like ion channels in the archaeon Haloferax volcanii". The Journal of Biological Chemistry. 272 (2): ...
Giménez MI, Cerletti M, De Castro RE (2015). "Archaeal membrane-associated proteases: insights on Haloferax volcanii and other ...
In the archaeal model species Haloferax volcanii, archaeosortase A belongs to a fairly large collection of identified membrane- ... Giménez MI, Cerletti M, De Castro RE (2015). "Archaeal membrane-associated proteases: insights on Haloferax volcanii and other ... The best characterized archaeosortase target is the Haloferax volcanii S-layer glycoprotein, an extensively modified protein ... "Haloferax volcanii archaeosortase is required for motility, mating, and C-terminal processing of the S-layer glycoprotein". Mol ...
... involvement in ammonium assimilation in Haloferax mediterranei". Extremophiles. 18 (1): 147-159. doi:10.1007/s00792-013-0606-9 ...
"Purification and characterization of aspartate aminotransferase from the halophile archaebacterium Haloferax mediterranei". The ...
"Long stretches of short tandem repeats are present in the largest replicons of the Archaea Haloferax mediterranei and Haloferax ... Mojica described the complete gene sequence repeats in the archaeal organisms Haloferax and Haloarcula species, and studied ... "Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites". Molecular ... "Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites". Molecular ...
Mojica, F. J.; Juez, G.; Rodríguez-Valera, F (1993). "Transcription at different salinities of Haloferax mediterranei sequences ...
Haloferax antrum, Haloferax opilio, Haloferax rutilus and Haloferax viridis were isolated from Romanian salt lakes and first ... PubMed references for Haloferax PubMed Central references for Haloferax Google Scholar references for Haloferax Haloferax at ... Haloferax litoreum, Haloferax marinisediminis and Haloferax marinum were first published in 2021, but are not accepted as of ... Haloferax marisrubri and Haloferax profundi were first published in 2020, but is not accepted as of 2022. Haloferax ...
Haloferax volcanii, part of the family of single-celled organisms called archaea that until recently were thought to be a type ... Haloferax volcanii, part of the family of single-celled organisms called archaea that until recently were thought to be a type ... The salt-loving Haloferax volcanii studied in the current paper originates from the Dead Sea. The discovery comes in the same ... This is how they resemble Haloferax volcanii. One of the other hallmarks of cancer cells is that grow faster than ordinary ...
Haloferax volcanii immersed liquid biofilms develop independently of known biofilm machineries and exhibit rapid honeycomb ... Haloferax volcanii immersed liquid biofilms develop independently of known biofilm machineries and exhibit rapid honeycomb ... Haloferax volcanii immersed liquid biofilms develop independently of known biofilm machineries and exhibit rapid honeycomb ... Haloferax volcanii immersed liquid biofilms develop independently of known biofilm machineries and exhibit rapid honeycomb ...
The present study sought to identify dolichol phosphate reductases in the halophilic archaeon, Haloferax volcanii. Homology- ... Haloferax volcanii." Biochim Biophys Acta, vol. 1821, no. 6, June 2012, pp. 923-33. Pubmed, doi:10.1016/j.bbalip.2012.03.002. ... Haloferax volcanii." Biochim Biophys Acta 1821, no. 6 (June 2012): 923-33. https://doi.org/10.1016/j.bbalip.2012.03.002. ... Haloferax volcanii. Biochim Biophys Acta, 1821(6), 923-933. https://doi.org/10.1016/j.bbalip.2012.03.002 ...
Find proteins for D4GZE7 (Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / ... Crystal structure of the ubiquitin-like small archaeal modifier protein 2 from Haloferax volcanii.. Li, Y., Maciejewski, M.W., ... The discovery of ubiquitin-like small archaeal modifier protein 2 (SAMP2) that forms covalent polymeric chains in Haloferax ... The discovery of ubiquitin-like small archaeal modifier protein 2 (SAMP2) that forms covalent polymeric chains in Haloferax ...
Significantly, the Haloferax mediterranei ferredoxin was shown to be a highly thermostable protein. It was stable up to 60 °C ... Significantly, the Haloferax mediterranei ferredoxin was shown to be a highly thermostable protein. It was stable up to 60 °C ... N2 - Haloferax mediterranei is a halophilic archaeon that can grow using nitrate as the sole nitrogen source. A ferredoxin that ... Significantly, the Haloferax mediterranei ferredoxin was shown to be a highly thermostable protein. It was stable up to 60 °C ...
Methods and Results: Haloferax alexandrinus GUSF-1 (KF796625) during growth in the presence of 5 mmol L sup(-1) of selenite ... Significance and Impact of Study: There are no reports on conversion of selenite to Se sup(0) among the Haloferax genera, and ... Aim: To investigate the ability of Haloferax alexandrinus GUSF-1 (KF796625) to biosynthesize non-toxic elemental selenium (Se ... Conversion of selenite by Haloferax alexandrinus GUSF-1 (KF796625) to pentagonal selenium nanoforms which in vitro modulates ...
Haloferax volcanii ATCC 29605. 1.1.1.401. Identification and characterization of 2-keto-3-deoxy-L-rhamnonate dehydrogenase ...
Genomic Descr!ption and Characterization of Haloferax litoreum sp. nov., Haloferax marinisediminis sp. nov., and Haloferax ...
Gene Expression of Haloferax volcanii on Intermediate and Abundant Sources of Fixed Nitrogen ...
Haloferax mediterranei was utilized to produce poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). Byproduct streams from a ... Haloferax mediterranei was utilized to produce poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). Byproduct streams from a ... Haloferax mediterranei is an extreme halophilic archaeon that can maintain robust pure microbial culture in unsterile ... Wang, K.; Zhang, R. Production of Polyhydroxyalkanoates (PHA) by Haloferax Mediterranei from Food Waste Derived Nutrients for ...
"Biofilms formed by the archaeon Haloferax volcanii exhibit cellular differentiation and social motility, and facilitate ... "Biofilms formed by the archaeon Haloferax volcanii exhibit cellular differentiation and social motility, and facilitate ...
NRC-1, Haloferax volcanii DS2, Haloquadratum walsbyi DSM 16790, Natronomonas pharaonis DSM 2160 and Salinibacter ruber DSM ... NRC-1, Haloferax volcanii DS2, Haloquadratum walsbyi DSM 16790, Natronomonas pharaonis DSM 2160 and Salinibacter ruber DSM ... including Haloferax volcanii (Mullakhanbhai and Larsen, 1975), Haloarcula marismortui (Oren et al., 1990), Halorubrum sodomense ...
Archaea Haloferax volcanii. 6. Hours. 106684. Jantzer K, Zerulla K.... Range of salinities on which growth is possible Archaea ... Haloferax volcanii. 12 to 24. %. 106141. Allers T. Overexpression.... Motility speed of archaea Halobacterium halobium Archaea ...
CetZ1 from Haloferax volcanii - GDP bound monomer. 4ck5. Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain ... CetZ2 from Haloferax volcanii - GTPgS bound protofilament. 4b46. ...
Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites. Mol ...
0146 from Haloferax volcanii, are archaeal homologs of bacterial phosphatidylserine decarboxylases (PssD) ... 129 Haloferax WP_004058516 83 TDVHVNRAPVSGTVSDVTHRPGAHKPAFSKDSDRNERVDITVDSDd---------------------------------- 128 Haloferax ... gEYEVSLIAGAFARRIHSYVAPGDELVRGQKLGHIDFGSRADVLLPPEYGSEDVIVEKGESVRAGETVLAR 200 Haloferax WP_004058516 129 --------gDYEVSLIAGAFARRI ... 008091193 3 FAPGYRRFALPAFVGAALASFVFPPLGAVLLAVGAFVLWFFRDPERSPPdEPGVVSPADGHVSVIRVEDGRVRVGVFMNV 82 Haloferax WP_004058516 3 FAPGYR ...
Currently we are working on the following projects using the halophilic archaea Haloferax volcanii, Natrialba magadii, ...
Aktivierung und Reprimierung der Gasvesikelbildung in Haloferax mediterranei. Technische Universität. Ph.D. Thesis, Primary ...
MicroLife article feature: Revealing the small proteome of Haloferax volcanii by combining ribosome profiling and small-protein ...
Golberg and Gozins technology uses microorganisms called Haloferax mediterranei, which could be harvested in very salty water ...
The enzyme from the archaeon Haloferax volcanii is specific for NAD+. cf. EC 1.1.1.363, glucose-6-phosphate dehydrogenase [NAD( ... Pickl, A. and Schonheit, P. The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel ...
Haloferax volcanii. Substrates and Products (Substrate). Substrates. Comment Substrates. Organism. Products. Comment (Products) ... Haloferax volcanii. dimethyl sulfoxide. 4°C, 72 h, retains 74% of its original activity following incubation with 5% (v/v) ... Haloferax volcanii. Methanol. 4°C, 72 h, retains 70% of its original activity following incubation with 5% (v/v) acetonitrile, ... Haloferax volcanii. Glycerol. stabilizing and cryoprotecting additive for the preservation of the enzyme over a short-time ...
Haloferax mucosum [1]. Halógeno [1]. Hamlet [1]. Hap [1]. haplogrupos mitocondriales [1]. ...
Das CRISPR-Cas-System von Haloferax volcanii: CRISPRi und Autoimmunität Stachler, Aris-Edda (2017) Dissertation ...
Haloferax Torreblanca et al. 1986 emend. Oren et al. 2009. (Part 3) ...
and Haloferax gibbonsii spec. nov., two new species of extremely halophilic archaebacteria. Syst Appl Microbiol 8:75-79 [ ...
Production of Polyhydroxyalkanoates from Hydrolysed Rapeseed Meal by Haloferax mediterranei. Khamplod, T., Wongsirichot, P. & ...
Haloferax volcanii ATCC 29605 D4GYH1_1-243 Glucose-1-phosphate uridylyltransferase Helicobacter pylori ATCC 700392 O25363_1-273 ...
Haloferax volcanii. Archaea. -. - -. O25158_HELPY. D-3-phosphoglycerate dehydrogenase. SERA. Helicobacter pylori 26695. ...
  • Haloferax mediterranei is a halophilic archaeon that can grow using nitrate as the sole nitrogen source. (uea.ac.uk)
  • Significantly, the Haloferax mediterranei ferredoxin was shown to be a highly thermostable protein. (uea.ac.uk)
  • Haloferax mediterranei was utilized to produce poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). (mdpi.com)
  • Golberg and Gozin's technology uses microorganisms called Haloferax mediterranei, which could be harvested in very salty water like in the Dead Sea. (ifcj.org)
  • In a sister species of archaea called Haloferax mediterranei, origins cannot be eliminated. (ukri.org)
  • This means that Haloferax mediterranei needs origins, while Haloferax volcanii can instead use recombination to start DNA replication. (ukri.org)
  • We propose that Haloferax volcanii has critical genes that are missing from Haloferax mediterranei, or vice versa. (ukri.org)
  • We will test these Haloferax species to see if their origins can be eliminated (as in Haloferax volcanii) or if they are essential (as in Haloferax mediterranei). (ukri.org)
  • Our results contrast with those obtained in Haloferax mediterranei, where origin-dependent replication is strictly required. (ukri.org)
  • His Genome research incorporates elements of Haloferax mediterranei and Metagenomics. (research.com)
  • Replacement of p-gvpA with mc-gvpA (from Haloferax mediterranei) led to the synthesis of gas vesicles that were narrower and stronger. (port.ac.uk)
  • Haloferax massilisiensis or Haloferax massiliense was first published in 2016 and again in 2018 as human associated halophilic archaeon. (wikipedia.org)
  • Scholars@Duke publication: A predicted geranylgeranyl reductase reduces the ω-position isoprene of dolichol phosphate in the halophilic archaeon, Haloferax volcanii. (duke.edu)
  • The present study sought to identify dolichol phosphate reductases in the halophilic archaeon, Haloferax volcanii. (duke.edu)
  • In the archaeon Haloferax volcanii, deletion of all origins or genes encoding initiator proteins leads to the initiation of replication by recombination - strikingly, this also leads to accelerated growth. (ukri.org)
  • Genome guided bioprospecting of extremely halophilic Haloferax sp. (unigoa.ac.in)
  • A rudimentary form of life, Haloferax volcanii , part of the family of single-celled organisms called archaea that until recently were thought to be a type of bacteria, is found in some of the harshest environments on earth. (science20.com)
  • Our research on DNA replication was carried out in Haloferax volcanii, a member of the archaea. (ukri.org)
  • Haloferax volcanii comes from the Dead Sea, we chose it because the enzymes that carry out DNA replication in archaea are similar to those in eukaryotes, such as human cells. (ukri.org)
  • Transformation experiments with Haloferax volcanii show that the amino acid sequence of the gas vesicle protein GvpA influences the morphology and strength of gas vesicles produced by halophilic archaea. (port.ac.uk)
  • Haloferax volcanii uses three origins to replicate its chromosome but when all origins are deleted, the cells grow faster. (ukri.org)
  • Haloferax has many copies of its chromosome, this is called polyploidy and helps it to survive when replication and cell division are not coordinated. (ukri.org)
  • Since it appears that origins are unnecessary in Haloferax volcanii , the scientists believe that replication origins in this organism could be an example of a 'selfish gene' - benefitting the origins by offering the chance to be continually replicated while offering no advantage to the organism itself. (science20.com)
  • The discovery of ubiquitin-like small archaeal modifier protein 2 (SAMP2) that forms covalent polymeric chains in Haloferax volcanii has generated tremendous interest in the function and regulation of this protein. (rcsb.org)
  • Members of this family, including founding member HVO_0146 from Haloferax volcanii, are archaeal homologs of bacterial phosphatidylserine decarboxylases (PssD). (nih.gov)
  • Pickl, A. and Schonheit, P. The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase - -The archaeal Zwischenferment. (enzyme-database.org)
  • Engineer Haloferax volcanii to produce butanol from glucose. (experiment.com)
  • As of 2022, 13 species are validly published under the genus Haloferax. (wikipedia.org)
  • Haloferax antrum, Haloferax opilio, Haloferax rutilus and Haloferax viridis were isolated from Romanian salt lakes and first proposed as new species in 2006. (wikipedia.org)
  • Haloferax berberensis was isolated in Algeria and proposed as new species in 2005. (wikipedia.org)
  • To simplify the search for these critical genes, we will study the genomes of these and up to 20 additional Haloferax species. (ukri.org)
  • Our colleagues in Romania have already discovered that salt lakes in Transylvania are a rich source of Haloferax species. (ukri.org)
  • Transcriptome studies of wild type Haloferax cells and the deletion mutant revealed up-regulation of six genes in the deletion strain, showing that the sRNA has a clearly defined function. (uni-stuttgart.de)
  • However, the study found that the Haloferax volcanii is able to spontaneously begin a chain reaction of replication all around its chromosomes even when its replication origins have been eliminated. (science20.com)
  • Loss of replication control leads to cancer cells making more than just two copies of their chromosomes, which is something they have in common with what the scientists observed in Haloferax volcanii . (science20.com)
  • Haloferax volcanii can use recombination to start DNA replication but this may be hazardous. (ukri.org)
  • This is similar to the faster growth we observe with origin-less Haloferax volcanii, which use an alternative mode of DNA replication. (ukri.org)
  • What we have discovered in Haloferax volcanii has parallels with cancer cells. (ukri.org)
  • The salt-loving Haloferax volcanii studied in the current paper originates from the Dead Sea. (science20.com)
  • Significance and Impact of Study: There are no reports on conversion of selenite to Se sup(0) among the Haloferax genera, and this study involving the formation of pentagonal SeNPs with capacity to modulate the formation of calcium oxalate crystals in haloarchaea is recorded as the first report and of significance in pharmaceutical research related to formulations abetting urinary calculi. (unigoa.ac.in)
  • Methods and Results: Haloferax alexandrinus GUSF-1 (KF796625) during growth in the presence of 5 mmol L sup(-1) of selenite formed insoluble brick-red particles. (unigoa.ac.in)
  • In taxonomy, Haloferax (common abbreviation: Hfx. (wikipedia.org)
  • Auch führt die gleichzeitige Anwesenheit von mcGvpD und mcGvpE in Haloferax volcanii-Transformanten zu einer starken Reduktion der mcGvpE-Menge und könnte somit den negativen Regulationsmechanismus der Gasvesikelbildung darstellen. (tu-darmstadt.de)
  • The pleomorphic archaeon Haloferax volcanii commonly forms discoid-shaped ('plate') cells in culture, but may also be present as rods, and can develop into motile rods in soft agar, or longer filaments in certain biofilms. (biorxiv.org)
  • The model haloarchaeon, Haloferax volcanii , when first isolated, was described as mainly disk-shaped cells, with cell shape and size varying significantly ( 1 ). (biorxiv.org)
  • Here, we adapt the ATAC-seq assay to archaea and use it to map the accessible landscape of the genome of the euryarchaeote Haloferax volcanii . (biomedcentral.com)
  • Applying orthogonal single-molecule footprinting methods, we quantify the absolute levels of physical protection of H. volcanii and find that Haloferax chromatin is similarly or only slightly more accessible, in aggregate, than that of eukaryotes. (biomedcentral.com)
  • In the haloarchaeon Haloferax volcanii , a series of Agl (archaeal glycosylation) proteins is responsible for the addition of an N-linked pentasaccharide to modified proteins, including the surface (S)-layer glycoprotein, the sole component of the surface layer surrounding the cell. (bgu.ac.il)
  • Here, for the first time in a member of the archaeal domain, we report a genome-wide assay of spontaneous mutations in the halophilic species Haloferax volcanii using a direct and unbiased method: mutation accumulation experiments combined with deep whole-genome sequencing. (elsevierpure.com)
  • Haloferax volcanii as immobilised whole cell biocatalyst: new applications for halophilic systems. (ukri.org)
  • The study, published in the journal Nature , centres on Haloferax volcanii - part of a family of single-celled organisms called archaea that until recently were thought to be a type of bacteria. (tgdaily.com)
  • The salt-loving Haloferax volcanii being studied by the Nottingham scientists originates from the Dead Sea. (tgdaily.com)
  • However, the Nottingham study, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Royal Society, found that the Haloferax volcanii is able to spontaneously begin a chain reaction of replication all around its chromosomes even when its replication origins have been eliminated. (tgdaily.com)
  • Since it appears that origins are unnecessary in Haloferax volcanii, the scientists believe that replication origins in this organism could be an example of a 'selfish gene' - benefitting the origins by offering the chance to be continually replicated while offering no advantage to the organism itself. (tgdaily.com)
  • 13. Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination. (nih.gov)
  • For example, the microbe Haloferax volcanii thrives here. (a-z-animals.com)
  • For the model archaeon Haloferax volcanii, this approach led to the identification of the largest archaeal glycoproteome described as yet, revealed the concurrence of two independent N-glycosylation pathways that can modify the same glycosylation sites, and indicated the involvement of glycosylation in crucial cellular processes such as cell shape determination. (rit.edu)
  • The haloarchaeon Haloferax volcanii was shown to contain 145 intergenic and 45 antisense sRNAs. (uni-frankfurt.de)
  • A bacterial riboswitch depending on theophylline was able to switch in the halophilic archaeon Haloferax volcanii , and lead to the translation depending on the theophylline concentration. (tu-darmstadt.de)
  • In contrast, a survey of the proteomes from various Euryarchaea (e.g., the halophile Haloferax volcanii , the hyperthermophiles Thermococcus gammatolerans and Pyrococcus furiosus , and the mesophile Methanococcus maripaludis ), did not reveal lysine methylation. (asmblog.org)
  • The enzyme, characterized from the archaeon Haloferax volcanii, specifically cleaves the ubiquitin-like small modifier proteins SAMP1 and SAMP2 from protein conjugates, hydrolyzing the isopeptide bond between a lysine residue of the target protein and the C-terminal glycine of the modifier protein. (expasy.org)
  • The application of Haloarchaeal Artificial Chromosomes for the analysis of the regulation of replicon copy numbers in the model species Haloferax volcanii will be introduced. (mpg.de)
  • His research in the fields of Promoter, Expression vector and Haloferax volcanii overlaps with other disciplines such as GvpA. (research.com)
  • My organism, Haloferax volcanii is up on the UCSC archaeal genome browser so I was considering trying to display the read pile up there. (seqanswers.com)
  • Archaea Haloferax volcanii N-glycosylation post-translational modification proteomic diversity Across evolution, analysis of the proteome reveals additional levels of complexity not predicted at the genome level. (silverchair.com)
  • Alice: Draft genome sequence of Haloferax sp. (embrapa.br)
  • Most representatives of the halophilic arachaeobacterial genera Halobacterium, Haloarcula and Haloferax tested were able to reduce dimethylsulfoxide (DMSO) to dimethylsulfide (DMS) and trimethylamine N-oxide (TMAO) to trimethylamine (TMA) under (semi)anaerobic conditions. (huji.ac.il)
  • Haloferax massilisiensis or Haloferax massiliense was first published in 2016 and again in 2018 as human associated halophilic archaeon. (wikipedia.org)
  • Familia de archaea extremadamente halofílica que se encuentra en ambientes con altas concentraciones de sal, como los lagos salados, salinas evaporadas o pescado salado. (bvsalud.org)
  • As of 2022, 13 species are validly published under the genus Haloferax. (wikipedia.org)
  • Organisms in the Haloferax genus are extreme halophiles that grow in environments with pH values between 4 and 12, and temperatures between 0°C and 60°C. In the present study, a draft of the first Haloferax sp. (embrapa.br)
  • DNA-DNA homology studies among strains of Haloferax and other halobacteria. (riken.jp)
  • In addition we are developing molecular biology tools based on CRISPR-Cas for application in Haloferax like the gene repression tool CRISPRi. (uni-ulm.de)
  • Haloferax marisrubri and Haloferax profundi were first published in 2020, but is not accepted as of 2022. (wikipedia.org)
  • Haloferax encodes a type I-B CRISPR-Cas system with eight Cas proteins (Cas1-Cas8b) and three CRISPR RNA locis. (uni-ulm.de)
  • Our results provide the first comprehensive maps of chromatin accessibility and active transcription in Haloferax across conditions and thus a foundation for future functional studies of archaeal chromatin. (biomedcentral.com)
  • The revised Student Handout for the Haloferax version begins with the driving question and a page that introduces students to DNA and its functions in order to motivate interest in the extraction of DNA that follows. (serendipstudio.org)