DeoxyriboseRibosemonophosphates: Ribose substituted in the 1-, 3-, or 5-position by a phosphoric acid moiety.Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.Pentoses: A class of carbohydrates that contains five carbon atoms.Aldehyde-Lyases: Enzymes that catalyze a reverse aldol condensation. A molecule containing a hydroxyl group and a carbonyl group is cleaved at a C-C bond to produce two smaller molecules (ALDEHYDES or KETONES). EC 4.1.2.Hydroxides: Inorganic compounds that contain the OH- group.Deoxyribonuclease IV (Phage T4-Induced): An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30.Deoxyribonucleosides: A purine or pyrimidine base bonded to DEOXYRIBOSE.Pyridoxal: The 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.Apurinic Acid: Hydrolysate of DNA in which purine bases have been removed.Ferrous Compounds: Inorganic or organic compounds that contain divalent iron.Free Radicals: Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.Zinostatin: An enediyne that alkylates DNA and RNA like MITOMYCIN does, so it is cytotoxic.Nogalamycin: An anthrocycline from a Streptomyces nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Ribose: A pentose active in biological systems usually in its D-form.DNA-(Apurinic or Apyrimidinic Site) Lyase: A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC 3.1.25.2.Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.PentosephosphatesEdetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.Nucleic Acid Conformation: The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.Nucleosides: Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)Oligonucleotides: Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)Deoxyribonucleotides: A purine or pyrimidine base bonded to a DEOXYRIBOSE containing a bond to a phosphate group.N-Glycosyl Hydrolases: A class of enzymes involved in the hydrolysis of the N-glycosidic bond of nitrogen-linked sugars.DNA Damage: Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.Glycolates: Derivatives of ACETIC ACID which contain an hydroxy group attached to the methyl carbon.Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.DNA Polymerase beta: A DNA repair enzyme that catalyzes DNA synthesis during base excision DNA repair. EC 2.7.7.7.Oligodeoxyribonucleotides: A group of deoxyribonucleotides (up to 12) in which the phosphate residues of each deoxyribonucleotide act as bridges in forming diester linkages between the deoxyribose moieties.Sugar AcidsFree Radical Scavengers: Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.Deoxyguanosine: A nucleoside consisting of the base guanine and the sugar deoxyribose.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Magnetic Resonance Spectroscopy: Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).Ferric Compounds: Inorganic or organic compounds containing trivalent iron.ThymineEndonucleases: Enzymes that catalyze the hydrolysis of the internal bonds and thereby the formation of polynucleotides or oligonucleotides from ribo- or deoxyribonucleotide chains. EC 3.1.-.DNA Repair-Deficiency Disorders: Disorders resulting from defective DNA REPAIR processes or the associated cellular responses to DNA DAMAGE.DNA Repair: The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.Endodeoxyribonucleases: A group of enzymes catalyzing the endonucleolytic cleavage of DNA. They include members of EC 3.1.21.-, EC 3.1.22.-, EC 3.1.23.- (DNA RESTRICTION ENZYMES), EC 3.1.24.- (DNA RESTRICTION ENZYMES), and EC 3.1.25.-.Xylitol: A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Dietary Carbohydrates: Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)Purines: A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.BooksPolymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Adenosine: A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.Phosphites: Inorganic salts or organic esters of phosphorous acid that contain the (3-)PO3 radical. (From Grant & Hackh's Chemical Dictionary, 5th ed)Pyrimidines: A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.Lesch-Nyhan Syndrome: An inherited disorder transmitted as a sex-linked trait and caused by a deficiency of an enzyme of purine metabolism; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE. Affected individuals are normal in the first year of life and then develop psychomotor retardation, extrapyramidal movement disorders, progressive spasticity, and seizures. Self-destructive behaviors such as biting of fingers and lips are seen frequently. Intellectual impairment may also occur but is typically not severe. Elevation of uric acid in the serum leads to the development of renal calculi and gouty arthritis. (Menkes, Textbook of Child Neurology, 5th ed, pp127)Purine-Nucleoside Phosphorylase: An enzyme that catalyzes the reaction between a purine nucleoside and orthophosphate to form a free purine plus ribose-5-phosphate. EC 2.4.2.1.Metabolome: The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.Metabolomics: The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.Phosphates: Inorganic salts of phosphoric acid.Purine Nucleosides: Purines with a RIBOSE attached that can be phosphorylated to PURINE NUCLEOTIDES.
Greenwood Publishing Group. 2007. p. 85. Krock, Lexi (22 April 2003). "Anatomy of Photo 51". NOVA online. PBS. Watson, James D ... The outside of the DNA chain has a backbone of alternating deoxyribose and phosphate molecules, and the base pairs, the order ... at King's College London in Sir John Randall's group. It was critical evidence in identifying the structure of DNA. James ... Crick, Francis (1953). "A Structure for Deoxyribose Nucleic Acid" (PDF). Nature. 171 (4356): 737-738. Bibcode:1953Natur.171.. ...
April 25 has since been declared "International DNA Day" and "World DNA Day" by several groups. Watson, James Dewey; Crick, ... Francis Harry Compton (1953-04-25). "Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid" (PDF). ...
A Structure for Deoxyribose Nucleic Acid" (PDF). Nature. London: Nature Publishing Group. 171 (4356): 737-738. Bibcode: ... Other processes that may promote cooperation include group selection, where cooperation provides benefits to a group of ... A set of alleles that is usually inherited in a group is called a haplotype. This can be important when one allele in a ... London: Nature Publishing Group on behalf of the Royal College of Ophthalmologists. 12 (3b): 541-547. doi:10.1038/eye.1998.143 ...
If the carbonyl group is an aldehyde, the monosaccharide is an aldose; if the carbonyl group is a ketone, the monosaccharide is ... Deoxyribose is a component of DNA. Lyxose is a component of lyxoflavin found in the human heart. Ribulose and xylulose occur in ... The aldehyde or ketone group of a straight-chain monosaccharide will react reversibly with a hydroxyl group on a different ... For example, deoxyribose, a component of DNA, is a modified version of ribose; chitin is composed of repeating units of N- ...
The 3´hydroxyl group in the deoxyribose ring of thymidine is replaced by an azido group which gives us zidovudine. The lack of ... hydroxyl group on the deoxyribose moiety. Once incorporated into the DNA chain, the absence of a 3´-hydroxyl group, which ... Insertion of a cyclopropyl group on its 6-amino nitrogen of the adenine ring increased lipophilicity and thus enhanced brain ... Dideoxynucleosides are analogues of nucleoside where the sugar ring lacks both 2´ and 3´-hydroxyl groups. Three years after the ...
dTMP consists of a phosphate group, the pentose sugar deoxyribose, and the nucleobase thymine. Unlike the other ...
One end of a DNA polymer contains an exposed hydroxyl group on the deoxyribose; this is known as the 3' end of the molecule. ... deoxyribose), a phosphate group, and one of the four bases adenine, cytosine, guanine, and thymine. Two chains of DNA twist ... Nature Publishing Group. 1 (1): 63. McCarthy D, Minner C, Bernstein H, Bernstein C (1976). "DNA elongation rates and growing ... Nature Publishing Group. 1 (1): 139. Nachman MW, Crowell SL (September 2000). "Estimate of the mutation rate per nucleotide in ...
The sugar in DNA is 2-deoxyribose, which is a pentose (five-carbon) sugar. The sugars are joined together by phosphate groups ... a sugar called deoxyribose, and a phosphate group. The nucleotides are joined to one another in a chain by covalent bonds ... end a terminal hydroxyl group. One major difference between DNA and RNA is the sugar, with the 2-deoxyribose in DNA being ... The group was able to encode 739 kilobytes of data into DNA code, synthesize the actual DNA, then sequence the DNA and decode ...
The 5'-phosphate group of one nucleotide is linked to the 3'-hydroxyl group of the next nucleotide, creating a backbone of ... DNA is defined by containing 2'-deoxy-ribose nucleic acid while RNA is defined by containing ribose nucleic acid. In some ... The general structure of a ribonucleotide consists of a phosphate group, a ribose sugar group, and a nucleobase, in which the ... Instead of a hydroxyl group at the second carbon in the ribose ring, it is replaced by a hydrogen atom. Both types of pentoses ...
... ribose or deoxyribose), a phosphate group, and a nucleobase. Nucleic acids are also generated within the laboratory, through ... If the sugar is a simple ribose, the polymer is RNA (ribonucleic acid); if the sugar is derived from ribose as deoxyribose, the ... In conventional nomenclature, the carbons to which the phosphate groups attach are the 3'-end and the 5'-end carbons of the ... They are composed of nucleotides, which are monomers made of three components: a 5-carbon sugar, a phosphate group and a ...
Each deoxyribonucleotide comprises three parts: a nitrogenous base, a deoxyribose sugar, and one phosphate group. The ... The phosphate groups bind to the 5' carbon of the sugar. When deoxyribonucleotides polymerize to form DNA, the phosphate group ... nitrogenous base is always bonded to the 1' carbon of the deoxyribose, which is distinguished from ribose by the presence of a ... proton on the 2' carbon rather than an -OH group. ...
Adenosine is adenine reacted with ribose as used in RNA and ATP; deoxyadenosine, adenine attached to deoxyribose, as is used to ... It forms adenosine triphosphate (ATP), a nucleoside triphosphate, when three phosphate groups are added to adenosine. Adenosine ... When connected into DNA, a covalent bond is formed between deoxyribose sugar and the bottom left nitrogen, so removing the ... Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose. ...
... combined with deoxyribose creates the nucleoside deoxythymidine, which is synonymous with the term thymidine. Thymidine ... can be phosphorylated with up to three phosphoric acid groups, producing dTMP (deoxythymidine monophosphate), dTDP, or dTTP ( ... Deoxyribose Deoxythymidine Nucleobase Pyrimidine Thymineless death Uracil Albrecht Kossel and Albert Neumann (1893) "Ueber das ...
DNA, however, requires deoxyribose, which is missing the 2'-hydroxyl (-OH group) on the ribose. The reaction to remove this -OH ... Unlike in purine synthesis, the sugar/phosphate group from PRPP is not added to the nitrogenous base until towards the end of ... Because of this, the two different groups are synthesized in different ways. However, all nucleotide synthesis requires the use ... A similar reaction can also be done with thymine and deoxyribose-1-phosphate. Deficiencies in enzymes involved in pyrimidine ...
... s are organized into two groups: Aldopentoses have an aldehyde functional group at position 1. Ketopentoses have a ... Ribose is a constituent of RNA, and the related molecule, deoxyribose, is a constituent of DNA. Phosphorylated pentoses are ... The aldehyde and ketone functional groups in these carbohydrates react with neighbouring hydroxyl functional groups to form ... The ring spontaneously opens and closes, allowing rotation to occur about the bond between the carbonyl group and the ...
The presence of an aldehyde group in a monosaccharide is indicated by the prefix aldo-. Similarly, a ketone group is denoted by ... and deoxyribose. Consumed fructose and glucose have different rates of gastric emptying, are differentially absorbed and have ... whose heads contain a positively charged group that is linked to the tail by a negatively charged phosphate group. Sterols, ... DNA uses the deoxynucleotides C, G, A, and T, while RNA uses the ribonucleotides (which have an extra hydroxyl(OH) group on the ...
The deoxyribose derivative found in DNA differs from ribose by having a hydrogen atom in place of the hydroxyl group at C2'. ... The "D-" in the name D-ribose refers to the stereochemistry of the chiral carbon atom farthest away from the aldehyde group (C4 ... It is related to deoxyribose, which is found in DNA. Phosphorylated derivatives of ribose such as ATP and NADH play central ... In the conventional numbering scheme for monosaccharides, the carbon atoms are numbered from C1' (in the aldehyde group) to C5 ...
... and one or more phosphate groups. In a nucleoside, the base is bound to either ribose or deoxyribose via a beta-glycosidic ... Thus, nucleosides can be phosphorylated by specific kinases in the cell on the sugar's primary alcohol group (-CH2-OH) to ... In addition, nucleotides can be broken down: inside the cell into nitrogenous bases, and ribose-1-phosphate or deoxyribose-1- ... Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of ...
... results from neighboring group participation. Stereoselective synthesis of deoxyribonucleosides directly from deoxyribose ... hydroxyl groups, removal of the 2'-hydroxyl group through a Barton deoxygenation, and deprotection. (9) A useful alternative to ... 8) Deoxyribose-derived electrophiles are unable to form the cyclic cation 1; as a result, the stereoselective synthesis of ... 4) 2-Deoxysugars are unable to form the cyclic cation intermediate 1 because of their missing benzoyl group; instead, under ...
The first phosphate group linked to the sugar is termed the α-phosphate, the second is the β-phosphate, and the third is the γ- ... The term nucleoside refers to a nitrogenous base linked to a 5-carbon sugar (either ribose or deoxyribose). Nucleotides are ... These enzymes covalently link the free -OH group on the 3' carbon of a growing chain of nucleotides to the α-phosphate on the 5 ... The nitrogenous base is linked to the 1' carbon through a glycosidic bond, and the phosphate groups are covalently linked to ...
However, unlike the natural deoxynucleotides substrates, NRTIs and NtRTIs lack a 3′-hydroxyl group on the deoxyribose moiety. ... NRTIs must be activated in the cell by the addition of three phosphate groups to their deoxyribose moiety, to form NRTI ...
In its composition, deoxythymidine is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base ... Deoxythymidine can be phosphorylated with one, two or three phosphoric acid groups, creating dTMP (deoxythymidine monophosphate ...
It is similar to guanosine, but with one hydroxyl group removed from the 2' position of the ribose sugar (making it deoxyribose ... Deoxyguanosine is composed of the purine nucleobase guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. ... If a phosphate group is attached at the 5' position, it becomes deoxyguanosine monophosphate. 8-Oxo-2'-deoxyguanosine "2'- ...
Alexander Todd determined that the backbone of a DNA molecule contained repeating phosphate and deoxyribose sugar groups. The ... Packaging of DNA is facilitated by the electrostatic charge distribution: phosphate groups cause DNA to have a negative charge ...
In the backbone of DNA the 5' carbon of one deoxyribose is linked to the 3' carbon of another by a phosphate group. The 5' ... carbon of this deoxyribose is again linked to the 3' carbon of the next, and so forth. When a molecule of DNA is double ... The numbers refer to the numbering of carbon atoms in the deoxyribose, which is a sugar forming an important part of the ...
This nucleotide contains the five-carbon succar deoxyribose, a nitrogenous base cried adenine, an ane phosphate group. ... Thegither, the deoxyribose an adenine mak up a nucleoside (speceefically, a deoxyribonucleoside) cried deoxyadenosine. Wi the ... ane phosphate group includit, whole structur is considered a deoxyribonucleotide (a nucleotide constituent o DNA) wi the name ...
Space Group: P 1 21 1. *Diffraction Data DOI: 3NDO Protein Diffraction ... Deoxyribose-phosphate aldolase. A, B. 231. Mycolicibacterium smegmatis. Mutation(s): 0 Gene Names: deoC, MSMEG_0922. EC: 4.1. ... Crystal structure of deoxyribose phosphate aldolase from mycobacterium smegmatis. *DOI: 10.2210/pdb3NDO/pdb ...
The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA ... THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ... Space Group: C 1 2 1 Unit Cell:. Length (Å). Angle (°). a = 87.26. α = 90.00. ...
It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.,p>,a href=/help ... Deoxyribose-phosphate aldolase (deoC). This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which ... Deoxyribose-phosphate aldolaseUniRule annotation. ,p>Manual validated information which has been generated by the UniProtKB ... sp,A0PVY3,DEOC_MYCUA Deoxyribose-phosphate aldolase OS=Mycobacterium ulcerans (strain Agy99) OX=362242 GN=deoC PE=3 SV=1 ...
... that is a constituent of DNA and differs from ribose in having a hydrogen atom instead of a hydroxyl group on one of its carbon ... deoxyribose synonyms, deoxyribose pronunciation, deoxyribose translation, English dictionary definition of deoxyribose. n. A ... deoxyribose. (diːˌɒksɪˈraɪbəʊs; -bəʊz) or desoxyribose. n. (Biochemistry) a pentose sugar obtained by the hydrolysis of DNA. ... deoxyribose. Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.. Related to deoxyribose: phosphodiester bond ...
It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.,p>,a href=/help ... Deoxyribose-phosphate aldolase (deoC). This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which ... Deoxyribose-phosphate aldolaseUniRule annotation. ,p>Manual validated information which has been generated by the UniProtKB ... sp,Q18C22,DEOC_PEPD6 Deoxyribose-phosphate aldolase OS=Peptoclostridium difficile (strain 630) OX=272563 GN=deoC PE=3 SV=1 ...
Deoxyribose is an aldopentose, which means a pentose sugar with an aldehyde functional group in position 1. An aldehyde group ... Deoxyribose, also known as D-Deoxyribose and 2-deoxyribose, is a pentose sugar (monosaccharide containing five carbon atoms) ... and a phosphate group. Levene had discovered ribose in 1909. Biological Importance of Deoxyribose. Deoxyribose and ribose ... is attached to the fifth carbon atom and a hydroxyl group. Deoxyribose is formed by the replacement of the hydroxyl group at ...
DNA, unlike RNA, lacks a hydroxyl (-OH) group at the 2 carbon. Since there is no hydroxyl group, DNA can only form ... Biological Importance of Deoxyribose[edit]. 2-deoxyribose, as well as ribose, derivatives are important in biological processes ... The structure of deoxyribose in DNA Deoxyribose is an aldopentose, meaning that it is a monosaccharide which contains five ... Deoxyribose Sugar[edit]. Typically, deoxyribonucleic acid is depicted as the nucleic acid that serves as the template for the ...
5 Carbon Sugar (Deoxyribose) Remember that the sugar Deoxyribose is a carbohydrate, it is in a ring and ends in -ose. Carbs ... Phosphate group The phosphorus (P) in the phosphate group is what helps determine what biomolecule this is a part of...remember ... 5 Carbon Sugar (Deoxyribose) Remember that the sugar Deoxyribose is a carbohydrate, it is in a ring and ends in -ose. Carbs ... Phosphate group The phosphorus (P) in the phosphate group is what helps determine what biomolecule this is a part of...remember ...
Involved in transferase activity, transferring glycosyl groups. Specific function:. May have a role in maintaining the ... Deoxyribose 1-phosphate. Description. Deoxyribose 1-phosphate belongs to the class of organic compounds known as pentoses. ... Deoxyribose 1-phosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Deoxyribose 1-phosphate ... Within humans, deoxyribose 1-phosphate participates in a number of enzymatic reactions. In particular, guanine and deoxyribose ...
Greenwood Publishing Group. 2007. p. 85. Krock, Lexi (22 April 2003). "Anatomy of Photo 51". NOVA online. PBS. Watson, James D ... The outside of the DNA chain has a backbone of alternating deoxyribose and phosphate molecules, and the base pairs, the order ... at Kings College London in Sir John Randalls group. It was critical evidence in identifying the structure of DNA. James ... Crick, Francis (1953). "A Structure for Deoxyribose Nucleic Acid" (PDF). Nature. 171 (4356): 737-738. Bibcode:1953Natur.171.. ...
April 25 has since been declared "International DNA Day" and "World DNA Day" by several groups. Watson, James Dewey; Crick, ... Francis Harry Compton (1953-04-25). "Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid" (PDF). ...
Deoxyribose (chemical compound) Deoxyribose, also called d-2-deoxyribose, five-carbon sugar component of DNA (q.v.; ... Ribose, also called D-ribose, five-carbon sugar found in RNA (ribonucleic acid), where it alternates with phosphate groups to ... deoxyribonucleic acid), where it alternates with phosphate groups to form the backbone of the DNA ... ...
OH group at the 3′-position of the deoxyribose. ... and a cleavable chemical group to cap the - ... viii) cleaving the cleavable chemical group capping the -OH group at the 3′-position of the deoxyribose to uncap the -OH group ... viii) cleaving the cleavable chemical group capping the -OH group at the 3′-position of the deoxyribose to uncap the -OH group ... viii) cleaving the cleavable chemical group capping the -OH group at the 3′-position of the deoxyribose to uncap the -OH group ...
The strands are made up of subunits called nucleotides, each containing a sugar (deoxyribose), a phosphate group, and one of ... Phosphate group: A grouping of one phosphorus atom and four oxygen atoms that occurs in a nucleotide. ... COPYRIGHT 2001 The Gale Group, Inc.. Nucleic Acids. Nucleic acids are a group of organic compounds that carry genetic ... The sugar in DNA, however, is 2′-deoxyribose.. In DNA, each base is linked by a β -glycosidic bond to the C1′ position of the 2 ...
These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. Deoxyribose 5- ... Deoxyribose 5-monophosphate. Description. Deoxyribose 5-monophosphate belongs to the class of organic compounds known as ... Showing metabocard for Deoxyribose 5-monophosphate (HMDB0059654). Jump To Section: IdentificationTaxonomyOntologyPhysical ... 1. Putative deoxyribose-phosphate aldolase. General function:. Involved in catalytic activity. Specific function:. Catalyzes a ...
Deoxyribose is the main building block of DNA and is found in every nucleotide that makes up the long chain of genetic ... A deoxyribose is different from a ribose because it is missing one oxygen atom and does not contain the alcohol group. The ... A: The backbone of the DNA molecule is made of a repeated pattern containing a sugar called deoxyribose and a phosphate group. ... A: Nucleotides contain either ribose, found in RNA, or deoxyribose, found in DNA. Deoxyribose is not synthesized in the cell, ...
Phosphate Group. Component of DNA or RNA nucleotide. Deoxyribose. A monosaccharide (sugar) found in each nucleotide in DNA. ...
... hydroxyl group of one nucleotide sugar to the 5′-hydroxyl group of the adjacent nucleotide sugar. These asymmetric ... In DNA the sugar is D-2-deoxyribose; in RNA the sugar is D-ribose. In DNA the purine bases are adenine (A) and guanine (G), and ... The circularity of the genetic map of E. coli was originally deduced from the overlapping, circularly permuted groups of linked ... They form an operon, a group of contiguous genes that is transcribed as a single unit and translated to produce the ...
A nucleotide contains three components: a phosphate group, a sugar and a nitrogenous base. The phosphate group and sugar are ... Deoxyribose has one fewer oxyge... Full Answer , Filed Under: * Molecular Biology & DNA ... A: The five-carbon sugar found in DNA nucleotides is called 2?-deoxyribose. It is similar to the ribose, a sugar found in RNA. ... In DNA, the sugar is deoxyribose; in RNA, the sugar is ribose. The sugar molecule then binds to one of several nitrogenous ...
hydroxyl group on the ribose sugar to deoxyribose, forming a deoxyribonucleotide (denoted dATP). All ribonucleotide reductase ... phosphate groups (triphosphate). The phosphoryl groups, starting with the group closest to the ribose, are referred to as the ... ribose). Three phosphate groups are attached at the 5 carbon atom of the pentose. ATP is also one of four monomers (. ... cation, almost always magnesium, which aids in stabilizing its highly charged phosphate groups. The presence of magnesium ...
Enzymes called peptidylarginine deiminases (PADs) hydrolyze the imine group of arginines and attach a keto group, so that there ... Nonpolar interactions between the histone and deoxyribose sugars on DNA. *Salt bridges and hydrogen bonds between side chains ... Recently it has been shown, that the addition of a serotonin group to the position 5 glutamine of H3, happens in serotonergic ... The addition of one, two, or many methyl groups to lysine has little effect on the chemistry of the histone; methylation leaves ...
... cycloimido groups, heterocycloimido groups, substituted amidino groups, heterocycloamidino groups, alkylcarbonylamino groups, ... in which R1 is methyl and R2 is deoxyribose. Thus, in such embodiments, the thymidine family member comprises thymidine or a ... arylcarbonylamino groups, substituted aminocarbonyl groups, alkoxycarbonyl groups, heteroaryl groups, cycloimido groups, ... One or more of the hydrocarbyl groups may be or may comprise a carbocyclic aryl group. Carbocyclic aryl groups are aryl groups ...
... deoxyribose phosphate (3?-dRP) termini resulting from an AP lyase cleavage and other related 3?-blocking groups, such as 3?- ... These are termed as AP lyases that cleave 3? to AP sites using a ?-elimination mechanism, leaving a 5?-phosphate group and a 3 ... Matsumoto, Y.. and Kim,K. (1995) Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair. Science, ... deoxyribose residue (long patch repair). Replication factor C, proliferating cell nuclear antigen and the structure-specific ...
Heredity PBL - Jose Roque, Kit Crews, David Garang, Caleb Habtegebriel by Caleb Habtegebriel | This newsletter was created with Smore, an online tool for creating beautiful newsletters for for educators, nonprofits, businesses and more
a nucleotide consisting of thymine, deoxyribose, and a phosphate group. It is a constituent of DNAAlso called: thymidine ...
  • The nucleobases are classified into two types: the purines, A and G, being fused five- and six-membered heterocyclic compounds, and the pyrimidines, the six-membered rings C and T. A fifth pyrimidine nucleobase, uracil (U), usually takes the place of thymine in RNA and differs from thymine by lacking a methyl group on its ring. (wikibooks.org)
  • Uracil has fundamentally the same structure as thymine, with the deletion of a methyl group at the 5' position. (sparknotes.com)