Diabetes (disambiguation)

Diabetes (disambiguation)

Gestational diabetes6

• For example, a person with gestational diabetes mellitus (GDM) may continue to be hyperglycemic after delivery and may be determined to have, in fact, type 2 diabetes. (diabetesjournals.org)
• To examine possible markers for undiagnosed type 2 diabetes in early-onset gestational diabetes mellitus (GDM). (bioportfolio.com)
• Clinical Impact of the TCF7L2 Gene rs7903146 Type 2 Diabetes Mellitus Risk Polymorphism in Women with Gestational Diabetes Mellitus: Impaired Glycemic Control and Increased Need of Insulin Therapy. (bioportfolio.com)
• The single nucleotide polymorphism in TCF7L2 rs7903146 is associated with an increased risk of type 2 diabetes mellitus and gestational diabetes mellitus. (bioportfolio.com)
• and (iv) gestational diabetes mellitus. (springer.com)
• As far as pregnancy is concerned, we only need to address three types of diabetes: gestational diabetes mellitus (GDM), type 1 diabetes, and type 2 diabetes. (glowm.com)

Lipodystrophy16

• The comparison of studies is complicated by different measurement standards for lipodystrophy, the use of different race and ethnic groups, and a general lack of control groups. (thefreelibrary.com)
• Clinically, patients with severe lipodystrophy have severe insulin resistance and a group of unique features, such as severe hyperlipidemia, progressive liver disease, and increased metabolic rate ( table 1 ). (uptodate.com)
• The combination of these morphologic changes and antiretroviral-associated metabolic derangements has been referred to as the lipodystrophy syndrome ( Figures 1-4 ). (thebodypro.com)
• Evidence from human and animal studies substantiate the importance of adipose tissue, where too little, as in lipodystrophy ( 1 ), or too much, as in obesity ( 2 , 3 ), leads to insulin resistance and diabetes. (diabetesjournals.org)
• Insulin resistance and metabolic complications are less common than with other lipodystrophy subtypes. (beds.ac.uk)
• Lipodystrophy is a general term that defines a group of disorders that are characterized by generalized or partial loss of adipose tissue in different areas of the body. (mhmedical.com)
• An inherited metabolic disorder mainly affecting young female adults characterized by insulin resistance with glucose intolerance, hypertriglyceridemia, and partial lipodystrophy. (mhmedical.com)
• Familial Partial Lipodystrophy was first described in the medical literature in 1970s independently by three groups of physicians, including Drs Ozer, Kobberling, and Dunnigan. (mhmedical.com)
• Abstract Familial lipodystrophy is a rare genetic condition in which individuals have, besides metabolic changes and body fat deposits, a type of cardiomyopathy that has not been well studied. (bvsalud.org)
• Congenital generalized lipodystrophy (CGL) with autosomal recessive inheritance is a rare disease and is characterized by the lack of adipose tissue, severe insulin resistance, and early metabolic disturbances. (bvsalud.org)
• Lipodystrophy: The Metabolic Link of HIV Infection with Insulin-Resistance SyndromePaula Freitas1, Davide Carvalho1, Selma Souto1, Antonio Sarmento1 and Jose Luis Medina1 Department of Endocrinology, Centro Hospitalar Sao Joao and University of Porto Medical School, Porto, Portugal1. (amazonaws.com)
• Congenital generalized lipodystrophy (CGL), also known as Berardinelli-Seip syndrome, is an autosomal recessive disorder characterized by marked paucity of adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset of diabetes ( Garg, 2004 ).For a general description and a discussion of genetic heterogeneity of congenital generalized lipodystrophy, see CGL1 ( OMIM ). (mendelian.co)
• Congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, is a rare autosomal recessive disease characterized by a near absence of adipose tissue from birth or early infancy and severe insulin resistance. (mendelian.co)
• Generalized lipodystrophy is a disorder characterized by loss of adipose tissue and, usually, metabolic disturbance due to deficiency of hormones derived from these tissues, most importantly leptin. (symptoma.com)
• Acquired generalized lipodystrophy (AGL) causes variable extent of fat loss and is usually accompanied by diabetes mellitus, hepatic steatosis and fibrosis and hypertriglyceridemia. (symptoma.com)
• The profound metabolic benefits seen with leptin in numerous forms of leptin deficiency, including lipodystrophy, provide hope for the opportunity to identify selected subsets of patients who could benefit from leptin treatment. (bioscientifica.com)

Dyslipidemia13

• Obese patients with more visceral fat are more likely to suffer from type 2 diabetes mellitus, hypertension, dyslipidemia and obs. (bioportfolio.com)
• Following T2DM, dyslipidemia is known well for the main reason of vascular complication leading to atherosclerosis and impaired life expectancy in diabetes. (bioportfolio.com)
• The aims of this study were to examine the expression level of SCUBE2 in T2DM patients with dyslipidemia and its correlation with endothelial dysfunction marker, endothelin-1 (ET-1) in this group. (bioportfolio.com)
• DeFronzo [ 5 ] states that insulin resistance and Type II diabetes have been linked to clusters of cardiovascular and metabolic disorders including hypertension, obesity, glucose intolerance, dyslipidemia, and endothelial dysfunction. (hindawi.com)
• OBJECTIVE- Metabolic syndrome is characterized by the variable coexistence of obesity, hyperinsulinemia, insulin resistance, dyslipidemia, and hypertension. (diabetesjournals.org)
• Metabolic syndrome is characterized by the variable coexistence of excess of body fat, hyperinsulinemia (insulin resistance and glucose intolerance), dyslipidemia (high triglycerides and total cholesterol plasma levels), and hypertension ( 1 , 2 ). (diabetesjournals.org)
• median age, 36 years), the clinical and biochemical characteristics of NAFLD, and particularly its association with diabetes, dyslipidemia, hyperinsulinemia and/or with the increase of parameters of oxidative stress (blood levels of malonyldialdehyde, 4-hydroxynonenal and total plasma antioxidant capacity). (thedoctorsdoctor.com)
• RESULTS: Ninety percent of patients had an increased body mass index (BMI), 35% had dyslipidemia, 40% had sub-clinical diabetes (only 3% had overt diabetes), 60% had hyperinsulinemia, and more than 90% had enhanced levels of lipid peroxidation markers. (thedoctorsdoctor.com)
• CONCLUSIONS: Our data indicate that in our country, NAFLD may occur in young males with an increased BMI, with or without hyperinsulinemia, dyslipidemia and diabetes, generally associated with disorders of redox status, and that it may be differentiated from steatosis to steatohepatitis or cirrhosis only with a liver biopsy. (thedoctorsdoctor.com)
• Type 2 diabetes mellitus is characterizedby reduced postprandial adiponectin response: a possible link with diabeticpostprandial dyslipidemia. (biovendor.com)
• However, the widespread use of effective ART has coincided with increasing reports of metabolic abnormalities such as impaired glucose metabolism and insulin resistance, lactic acidosis, osteopenia, and dyslipidemia. (thebodypro.com)
• PCOS is associated with insulin resistance, type 2 diabetes mellitus, dyslipidemia, and visceral obesity. (springer.com)
• Metabolic abnormalities develop in adolescence or adulthood, leading to signs and symptoms that may include insulin resistance , dyslipidemia , diabetes, pancreatitis (or recurrent acute pancreatitis), liver steatosis , atherosclerosis, and an increased risk of heart disease. (cdc.gov)

Syndrome32

• 1,2 Attention has been paid to these rare disorders because they provide insight into several aspects of insulin action at the molecular level and advance our understanding of the more common insulin resistant disorders, such as polycystic ovarian syndrome 3 and type 2 diabetes mellitus. (springer.com)
• Acute, life-threatening consequences of uncontrolled diabetes are hyperglycemia with ketoacidosis or the nonketotic hyperosmolar syndrome. (diabetesjournals.org)
• With the increasing number of patients affected with metabolic diseases such as type 2 diabetes, obesity, atherosclerosis and insulin resistance, academic researchers and pharmaceutical companies are eager to better understand metabolic syndrome and develop new drugs for its treatment. (mdpi.com)
• Syndromes of extreme insulin resistance (SEIR) represent an extreme end of a spectrum disorder of insulin resistance due a defect either in the insulin receptor or downstream in the insulin signalling pathway [Leprechaunism, Rabson-Mendenhall syndrome (RMS), Type-A syndrome, lipoatrophic diabetes], or auto antibodies to insulin receptor/insulin. (jcrpe.org)
• Importantly, both LA in the lower part of the body and abdominal LH have been associated with metabolic changes akin to the metabolic syndrome, particularly dyslipidaemia and insulin resistance. (thefreelibrary.com)
• Additionally, insulin resistance involves an abnormal biological response of the body systems with regard to physiological levels of insulin, and this pathological feature of the disease is the key to the metabolic syndrome. (hindawi.com)
• It is well known that angiotensin (Ang) II is importantly involved in the metabolic syndrome. (diabetesjournals.org)
• CONCLUSIONS- These results show that Mas deficiency in FVB/N mice leads to dramatic changes in glucose and lipid metabolisms, inducing a metabolic syndrome-like state. (diabetesjournals.org)
• The metabolic syndrome pathogenesis is multifactorial and is related to central obesity, a sedentary lifestyle, an unbalanced diet, and genetic predisposition. (diabetesjournals.org)
• however, the molecular mechanisms underlying insulin resistance in metabolic syndrome are complex and not fully understood ( 4 ). (diabetesjournals.org)
• The renin-angiotensin (Ang) system (RAS) is an important link between metabolic syndrome and cardiovascular diseases. (diabetesjournals.org)
• Generalized lipoatrophy, also known as Lawrence-Seip syndrome, is a rare group of syndromes, either acquired or congenital, characterized by a near-complete absence of fat. (medscape.com)
• Altogether, adiponectin has the potential to become a clinically relevant parameter to be measured routinely in subjects at risk for type 2 diabetes, atherosclerosis and the metabolic syndrome. (biovendor.com)
• As the metabolic alterations coinciding with the availability of effective ART are similar to the features seen in the metabolic syndrome ("syndrome X"), one of the major concerns has been the potential for increased cardiovascular morbidity and mortality in this cohort. (thebodypro.com)
• 7 , 8 In addition, both the fat accumulation component and the fat depletion component of the syndrome are associated with substantial metabolic dysregulation that may have an impact on long-term cardiovascular morbidity and mortality in HIV-positive patients. (thebodypro.com)
• In this chapter, we will discuss the role of insulin resistance in the pathogenesis of PCOS, the risk of diabetes mellitus in this population, and the role of insulin-sensitizing agents, oral contraceptive pills, and antiandrogens in treating patients with polycystic ovary syndrome. (springer.com)
• wherein and n are defined in the description a salt, prodrug or complex thereof, which can be used for the treatment and/or prevention of syndrome X, obesity, hypertension, fatty liver, diabetes, hyperglycaemia, hyperinsulinemia and stenosis. (allindianpatents.com)
• Further, the invention relates to the use of the novel fatty acid analogues for the treatment and/or prevention of syndrome X, obesity, hypertension, fatty liver, diabetes, hyperglycaeinia, hyperinsulinemia and stenosis. (allindianpatents.com)
• There is an epidemic of obesity and the metabolic syndrome in the United States and across the world. (asnjournals.org)
• Several recent epidemiologic studies have shown that obesity and the metabolic syndrome are independent predictors of CKD. (asnjournals.org)
• In addition to diabetes and hypertension, several other mechanisms have been postulated to initiate and maintain kidney injury in patients with obesity and the metabolic syndrome. (asnjournals.org)
• This article reviews the recent epidemiologic data linking obesity and the metabolic syndrome to CKD and summarizes the potential mechanisms of renal injury in this setting, with a focus on the role of inflammation, lipotoxicity, and hemodynamic factors. (asnjournals.org)
• The metabolic syndrome, previously known as syndrome X and a major consequence of obesity, is also on the rise ( 6 ). (asnjournals.org)
• A central feature of the metabolic syndrome is insulin resistance, which results in hyperglycemia and hyperinsulinemia, and eventually leads to the development of diabetes ( 9 ). (asnjournals.org)
• Chronic inflammation is another feature of the metabolic syndrome, which, together with insulin resistance, results in complex metabolic derangements that contribute to the pathogenesis of hypertension, lipoprotein abnormalities, atherosclerosis, coronary artery disease, and other organ dysfunction ( 10 , 11 ). (asnjournals.org)
• Both obesity and the metabolic syndrome are associated with high mortality, mainly related to cardiovascular disease ( 12 , 13 ). (asnjournals.org)
• Overweight, obesity, and the metabolic syndrome have recently emerged as strong independent risk factors for chronic kidney disease (CKD) and ESRD. (asnjournals.org)
• This article reviews the epidemiology of CKD in relationship to obesity and the metabolic syndrome and the possible mechanisms of renal injury that is caused by obesity and obesity-initiated metabolic syndrome, with a focus on the role of inflammatory cytokines, abnormal lipid metabolism, and potential hemodynamic factors that remain largely underappreciated. (asnjournals.org)
• Hypertension and diabetes, two major consequences of obesity and the metabolic syndrome and certainly important contributors to CKD, are beyond the scope of this review. (asnjournals.org)
• CMR Short Reviews The Concept of CMR Historical background on global cardiometabolic risk, epidemiological aspects of obesity and type 2 diabetes, ABCs of cardiovascular disease risk factors, intra-abdominal adiposity, metabolic syndrome and contribution to cardiometabolic risk. (amazonaws.com)
• Elevated waist circumference, a crude anthropometric index of the absolute amount of intra-abdominal adipose tissue, better predicts the risk of developing the metabolic syndrome and related disorders than BMI. (amazonaws.com)
• The molecular mechanisms of body weight and body composition regulation have long been a research focus in the hopes of identifying tractable pathways for therapeutic interventions for obesity and diabetes, as well as related disorders such as nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) and polycystic ovary syndrome. (bioscientifica.com)

Management of Diabetes Mellitus2

• A Review of Basal-Bolus Therapy Using Insulin Glargine and Insulin Lispro in the Management of Diabetes Mellitus. (bioportfolio.com)
• Cinnamon has been used as a dietary component and in the management of diabetes mellitus. (bioportfolio.com)

Hypertension4

• Dominant negative mutation in human PPAR gamma associated with severe insulin resistance, diabetes mellitus, and hypertension. (springer.com)
• Hypertension and abnormalities of lipoprotein metabolism are often found in people with diabetes. (diabetesjournals.org)
• Apart from that, Type II diabetes has also been referred to as obesity-associated insulin resistance and implicated in the development of hypertension and atherosclerosis. (hindawi.com)
• 15 ) found that a higher BMI was a strong independent risk factor for ESRD even after adjustment for other major risk factors that are associated with ESRD, including smoking, baseline hypertension, and diabetes. (asnjournals.org)

Adipose7

• The lipodystrophic syndromes are a heterogeneous group of congenital or acquired disorders characterized by either complete or partial lack of adipose tissue (lipoatrophy) [ 1,2 ]. (uptodate.com)
• 13 , 14 Elevated levels of cytokines as well as macrophages capable of producing such cytokines have been reported in subcutaneous adipose tissue from lipoatrophic subjects. (thebodypro.com)
• Excessive adipose accumulation is a key pathological contributor to insulin resistance, which, in the presence of dysfunctional β-cell insulin secretion, leads to type 2 diabetes. (diabetesjournals.org)
• Regardless, there are numerous reports demonstrating regional adipose depot differences in gene regulation ( 12 , 13 , 14 , 15 ), lipolysis ( 16 , 17 ), response to weight loss ( 18 , 19 ), and even metabolic response to feeding ( 20 ). (diabetesjournals.org)
• However, adipocyte production in non-adipose tissues, such as skeletal muscle and bone marrow, is associated with chronic disease and aging. (ubc.ca)
• The main clinical manifestations were loss of adipose tissue, subcutaneous nodules, insulin-resistant diabetes, hypertriglyceridemia, and hepatic steatosis. (bvsalud.org)
• Given that abdominal obesity is one of the most prevalent forms of type 2 diabetes, therapeutic approaches should focus on reducing intra-abdominal adipose tissue. (amazonaws.com)

Pathogenesis6

• The investigators hypothesize that macrophages play a crucial role in the pathogenesis of atherosclerosis in patients with type 2 diabetes mellitus (T2DM). (bioportfolio.com)
• Many researchers agree that Type II diabetes is predominantly caused by impairment of the insulin-signalling pathway, even though the exact disease pathogenesis is yet to be understood. (hindawi.com)
• Diabetes is a chronic multisystem disease of complex and variable pathogenesis, associated with multiple long-term complications, predominately involving the vasculature. (scribd.com)
• Diabetes Mellitus And Its Complications Pathogenesis And Treatment Diabetes Mellitus And Its Complications Pathogenesis And Treatment by Angelika Foerster High sugar reading in 6 year old? (bestcities.eu)
• Home / Alternative medicine How to use natural remedies to control diabetes better Diabetes can be effectively managed with the help of methi (fenugreek) Pathogenesis of diabetes complications. (diabetestalk.net)
• Disrupted pancreatic β-cell function is a key event in the pathogenesis of diabetes mellitus, a metabolic disorder resulting in elevated blood sugar levels. (ubc.ca)

Disorders10

• As a rule, localized lipodystrophies are not associated with metabolic or systemic disorders, they tend to resolve spontaneously, and they have an excellent prognosis. (medscape.com)
• Insulin resistance is a key factor in metabolic disorders like hyperglycemia and hyperinsulinemia, which are promoted by obesity and may later lead to Type II diabetes mellitus. (hindawi.com)
• Diabetes mellitus is a group of diseases associated with various metabolic disorders, the main feature of which is chronic hyperglycemia due to insufficient insulin action. (springer.com)
• The long-term persistence of metabolic disorders can cause susceptibility to specific complications and also foster arteriosclerosis. (springer.com)
• subgroup A is diabetes in which a genetic abnormality has been identified, and subgroup B is diabetes associated with other pathologic disorders or clinical conditions. (springer.com)
• Therapy for Diabetes Mellitus and Related Disorders is the most comprehensive clinical reference work available on the disease. (scribd.com)
• All of these disorders collectively account for only 1% to 5% of cases of diabetes (see Part D of this chapter later on). (oncohemakey.com)
• Ensuring a correct diagnosis and defining the correct type of diabetes is important for choosing the most appropriate therapy, managing the expected complications, anticipating associated disorders, and predicting disease risk in relatives or reoccurrence in offspring. (oncohemakey.com)
• Part D: Other Specific Types of Diabetes Mellitus and Causes of Hyperglycemia, discusses diabetes in infants less than 6 months at diagnosis as well as the differential diagnosis of patients with an autosomal dominant or maternally transmitted patterns of diabetes inheritance as well as diabetes associated with medication or other endocrine disorders. (oncohemakey.com)
• The metabolic consequences of obesity and type 2 diabetes (T2D) were already a focus of the world's attention in 1994 when the discovery of leptin generated enormous enthusiasm for the potential to treat common (non-monogenic) obesity and its associated metabolic disorders with an adipokine hormone that regulated body weight as well as lipid and carbohydrate metabolism. (bioscientifica.com)

Hypertriglyceridemia1

• Hypertriglyceridemia , liver cirrhosis , diabetes mellitus , as well as cardiovascular complications are frequently observed. (symptoma.com)

Cases of diabetes mellitus1

• Relative insulin deficiency is the cause of most cases of diabetes mellitus. (tripod.com)

Abnormalities4

• The basis of the abnormalities in carbohydrate, fat, and protein metabolism in diabetes is deficient action of insulin on target tissues. (diabetesjournals.org)
• The extent of fat loss correlates with the severity of the metabolic abnormalities. (uptodate.com)
• Distressing morphologic changes in body habitus associated with these metabolic abnormalities are characterized by accumulation of fat in the abdomen (visceral fat compartment) and in the dorsocervical area of the neck, as well as by the depletion of fat in the face, buttocks, and extremities. (thebodypro.com)
• Furthermore, although some of the metabolic disturbances may be linked to one another, the interconnections among these metabolic abnormalities have yet to be elucidated. (thebodypro.com)

Meta-analysis of Randomized Clinic1

• Effects of Insulin Treatment with Glargine or Premixed Insulin Lispro Programs in Type 2 Diabetes Mellitus Patients: A Meta-analysis of Randomized Clinical Trials. (bioportfolio.com)

Classification2

• Greek: 'diabetes' - "siphon" or "to pass through" Latin: 'mellitus' - "honeyed" or "sweet"** * Diagnosis and Classification of Diabetes Mellitus. (slideplayer.com)
• Clark C Jr: Report of the Expert Committee on the diagnosis and classification of Diabetes Mellitus. (glowm.com)

HYPERINSULINEMIA3

• This group of syndromes shares severe insulin resistance and hyperinsulinemia with variable clinical manifestations. (springer.com)
• WO 99/58122 describes use of fatty acid analogues for the treatment and/or prevention of diabetes (both type I and II), and a method for the treatment or prevention of hyperglycaemia, hyperinsulinemia and reduced sensitivity to insulin. (allindianpatents.com)
• In the following list you will find some of the most common rare diseases related to Cardiomyopathy and Hyperinsulinemia that can help you solving undiagnosed cases. (mendelian.co)

Type of diabetes4

• Individuals at increased risk of developing this type of diabetes can often be identified by serological evidence of an autoimmune pathologic process occurring in the pancreatic islets and by genetic markers. (diabetesjournals.org)
• Assigning a type of diabetes to an individual often depends on the circumstances present at the time of diagnosis, and many diabetic individuals do not easily fit into a single class. (diabetesjournals.org)
• ICD-10-CM diabetes codes are combination codes that include the type of diabetes mellitus, body system affected, and the complications affecting that body system. (diabetestalk.net)
• ICD-10-CM Diabetes Mellitus Coding Examples ICD-10-CM diabetes codes are combinations codes that include the type of diabetes mellitus, body system affected, and the complications affecting that body system. (diabetestalk.net)

Hepatomegaly1

• This metabolic disorder is associated with heart problems (angina), cirrhosis and hepatomegaly, lipoatrophic diabetes, and pancreatitis. (mhmedical.com)

Genetic4

• Although Type II diabetes has been asserted to have a genetic linkage [ 4 ], the key here is insulin resistance, which can be exacerbated by lifestyle changes and unhealthy dietary intake [ 3 ]. (hindawi.com)
• Köbberling J. Genetic syndromes associated with lipoatrophic diabetes. (uptodate.com)
• According to diabetes 2 diet and exercise research your gut bacteria are the most accurate preditors for obesity compared to any other risk factors found what are the symptoms for diabetes in your genetic pool1. (amazonaws.com)
• Obesity is a chronic, multifactorial, and complex disease resulting from a long-term positive energy balance, in which both genetic and environmental factors are involved [ 3 , 4 ]. (pubmedcentralcanada.ca)

Glycemic control3

• In some individuals with diabetes, adequate glycemic control can be achieved with weight reduction, exercise, and/or oral glucose-lowering agents. (diabetesjournals.org)
• Other topics include glycemic control, diabetes complications and comorbidities, diabetes mellitus therapy in different patient groups, and much more. (scribd.com)
• The purpose of this study is to determine the efficacy and safety of SYR-472, once daily (QD), in subjects with type 2 diabetes mellitus who have not achieved glycemic control with diet and exercise, or by taking metformin. (clinicaltrials.gov)

Atherosclerosis3

• The present paper focuses on the current status of our knowledge regarding chronic inflammation, a link between obesity and CVDs, including heart diseases, vascular disease and atherosclerosis. (pubmedcentralcanada.ca)
• CVDs, including heart disease, vascular disease and atherosclerosis, are the most critical global health threat, contributing to more than one-third of the global morbidity. (pubmedcentralcanada.ca)
• In most cases, these clinical conditions result from atherosclerosis, which was once identified as a lipid-storage disease. (pubmedcentralcanada.ca)

Hepatic1

• E. : Generalized lipoatrophy, hepatic cirrhosis, disturbed carbohydrate metabolism and accelerated growth (lipoatrophic diabetes). (symptoma.com)

Disorder3

• Diabetes mellitus is a metabolic disorder signified by high levels of glucose in the blood and can be categorised into two main groups. (hindawi.com)
• Diabetes mellitus is associated with a broad range of clinical presentations, from being asymptomatic to ketoacidosis or coma, depending on the degree of metabolic disorder. (springer.com)
• Obesity, the most common nutritional disorder in industrialized countries, is associated with an increased mortality and morbidity of cardiovascular disease (CVD). (pubmedcentralcanada.ca)

T1DM5

• The association between type 1 diabetes mellitus (T1DM) and specific cardiovascular diseases (CVD) is uncertain. (bioportfolio.com)
• Type 1 Diabetes Mellitus (T1DM) is a well-studied autoimmune disease resulting in insulin deficiency due to selective β-cell destruction. (bioportfolio.com)
• 4 contact hour diabetes CEU course on type 1 diabetes mellitus (T1DM). (wildirismedicaleducation.com)
• Upon completion of this course, you will be better prepared to appropriately care for patients with type 1 diabetes mellitus (T1DM) by identifying its health effects and evidence-based treatment guidelines, as well as the actions necessary to manage the disease. (wildirismedicaleducation.com)
• The use of insulin is a mainstay of treatment for all individuals with type 1 diabetes mellitus (T1DM) and for many individuals with type 2 diabetes mellitus (T2DM). (dovepress.com)

T2DM4

• The purpose of this study was to compare the efficacy and safety of intensive insulin therapy (premixed insulin lispro vs. insulin glargine) in patients with type 2 diabetes mellitus (T2DM). (bioportfolio.com)
• Furthermore, data on type 2 diabetes mellitus (T2DM) in relation to risk of aortic valv. (bioportfolio.com)
• Thus, a new prediction marker in T2DM could help prevent the progression disease despite of metabolic control. (bioportfolio.com)
• To investigate the risk of mortality and hospitalization in individuals with post-pancreatitis diabetes mellitus (PPDM) compared with those with type 2 diabetes mellitus (T2DM). (bioportfolio.com)

GLUCOSE INTOLERANCE1

• Affected patients are insulin resistant and may develop glucose intolerance and diabetes mellitus after age 20 years. (mhmedical.com)

Diagnosis of diabetes5

• The same disease process can cause impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) without fulfilling the criteria for the diagnosis of diabetes. (diabetesjournals.org)
• Confirmation of chronic hyperglycemia is essential for the diagnosis of diabetes mellitus. (springer.com)
• Criteria for whom to screen and when are listed in Table 1.1.¹ Before 1997, the diagnosis of diabetes had been defined by the ADA as a fasting plasma glucose (FPG) ≥140 mg/dl (7.8 mmol/l) or a 2-hour PG during a 75-gram oral glucose tolerance test (OGTT) of ≥200 mg/dl (11.1 mmol/l). (scribd.com)
• The criteria for making the diagnosis of diabetes are the same, regardless of the etiology. (oncohemakey.com)
• In the absence of a preceding history of polydipsia and polyuria, a diagnosis of diabetes mellitus should not be made based on hyperglycemia documented during a serious illness. (oncohemakey.com)

Deficiency3

• A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. (bioportfolio.com)
• In one category, type 1 diabetes, the cause is an absolute deficiency of insulin secretion. (diabetesjournals.org)
• Type 1 diabetes is characterized by β-cell destruction, usually leading to absolute insulin deficiency. (slideplayer.com)

Mechanisms2

• Understanding these factors and their mechanisms may be essential for comprehending the progression of insulin resistance towards the development of diabetes mellitus. (hindawi.com)
• This study is designed to identify the mechanisms underlying peripheral edema formation with pioglitazone in patients with Type 2 diabetes. (clinicaltrials.gov)

Cardiovascular disease3

• Importantly, ATV is known to have a better lipid profile than EFV and LPV/r and an argument could therefore be made for its preferential use in patients at high risk for cardiovascular disease. (thefreelibrary.com)
• Both entities are associated with high mortality, mainly as a result of cardiovascular disease. (asnjournals.org)
• Among the evolving risk factors for cardiovascular disease, could you comment on the role of physical activity or inactivity? (amazonaws.com)

Placebo1

• Using a similar approach, the Diabetes Prevention Program randomly assigned 3,234 participants with IGT to a placebo with standard lifestyle recommendations, the antihyperglycemic agent metformin with standard lifestyle recommendations, or a lifestyle modification program designed to achieve and maintain a 7% body weight reduction (9). (amazonaws.com)

Children and Adolescents1

• About 10% have Type 1 DM 14.6 million diagnosed 6.2 million remain undiagnosed 41 million have pre-diabetes Lifetime risk for developing DM (Type 1 or 2) is 33 % in males and 39% in females for individuals born in 2000 Up to 45% of newly diagnosed cases of DM in US children and adolescents are type 2 AACE Diabetes Mellitus Guidelines, Endocr Pract. (slideplayer.com)

Diabetic9

• Family care topics include diabetes in pregnancy, diabetic ketoacidosis, childhood obesity, and type 2 diabetes in children. (scribd.com)
• Indeed, the presentation may be fulminant, accompanied by metabolic decompensation (i.e., diabetic ketoacidosis. (scribd.com)
• Type I diabetes also known as insulin-dependent diabetes is caused by the failure of the pancreas to produce enough insulin for prevention of spikes in blood sugar I am diabetic and I was drinking bitter gourd juice for almost a year. (bestcities.eu)
• Pre Diabetes 7 Day Meal Plan Eating 5 In order to do this while keeping your diabetes under control you must implement a diabetic diet system. (bestcities.eu)
• If the results are equivocal in order to formally assess the concentrating power of the kidneys Pre Diabetes How To Fix diabetic association of texas. (bestcities.eu)
• Diagnosis: A patient is seen for diabetic chronic kidney disease, stage 3. (diabetestalk.net)
• E11.22 Type 2 diabetes mellitus with diabetic chronic kidney disease N18.3 Chronic kidney disease, stage 3 (moderate) Z79.4 Long term (current) use of insulin Rationale: There is a combination code for the type 2 diabetes with chronic kidney disease, and the tabular instructs the coder to use an additional code to identify the stage of the chronic kidney disease. (diabetestalk.net)
• Diagnosis: A female patient with type 1 diabetes is seen for severe nonproliferative diabetic retinopathy with macular edema. (diabetestalk.net)
• Brittle Diabetes Icd 10 Fast Facts Sheet causes And Risk Factors Of Diabetes Type 2 diabetes controlling so you no longer have diet diabetic diabetes medications drug classes. (diabetestalk.net)

Form of diabetes2

• Diabetes mellitus type 1 (also known as type 1 diabetes) is a form of diabetes mellitus in which not enough insulin is produced. (diabetestalk.net)
• In males, insulin resistance progresses to a severe form of diabetes accompanied by pancreatic β cell failure. (jci.org)

People with diabetes1

• Nearly 100 of the world's leading medical researchers and clinicians share their expertise on the diagnosis, treatment, and care of people with diabetes mellitus. (scribd.com)

Acanthosis1

• Metabolic importance of acanthosis nigricans. (springer.com)

Prevalent2

• Obesity and type 2 diabetes mellitus are prevalent all over the world. (bioportfolio.com)
• In the other, much more prevalent category, type 2 diabetes, the cause is a combination of resistance to insulin action and an inadequate compensatory insulin secretory response. (diabetesjournals.org)

Development of diabetes2

• Several pathogenic processes are involved in the development of diabetes. (diabetesjournals.org)
• Their data suggested, furthermore, that the development of diabetes in the ob animal is a consequence of unlinked polygenes. (datapunk.net)

Disturbances1

• The causes of the metabolic disturbances and morphologic changes related to ART are not understood completely. (thebodypro.com)

Patients13

• Prevalence of early and late prematurity is similar among pediatric type 1 diabetes mellitus patients and the general population. (bioportfolio.com)
• Patients with diabetes have an increased incidence of atherosclerotic cardiovascular, peripheral arterial, and cerebrovascular disease. (diabetesjournals.org)
• Efficacy and safety of Cinnamon in Type 2 Diabetes Mellitus and Pre-diabetes patients: A Meta-analysis and Meta-regression. (bioportfolio.com)
• FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism. (medicalpark.com.tr)
• Transferring to insulin detemir from NPH insulin or insulin glargine in type 2 diabetes patients on basal-only therapy with oral antidiabetic drugs improves glycaemic control and reduces weight gain and risk of hypoglycaemia: 14-week follow-up data from PREDICTIVE. (medicalpark.com.tr)
• Our investigation was held to observe the main clinical, histological, and pathophysiological aspects of NAFLD in patients not exposed to any known cause of chronic liver disease. (thedoctorsdoctor.com)
• Acquired and congenital lipodystrophies may also be associated with proteinuric kidney diseases, and renal biopsy of patients with nephrotic range proteinuria has revealed focal segmental glomerulosclerosis or membranoproliferative glomerulonephritis [ 3,4 ]. (uptodate.com)
• Low serum adiponectin levels are found in patients with coronary artery disease. (biovendor.com)
• The purpose of this study is to measure microcirculation in type 2 diabetes patients with peripheral edema who are taking pioglitazone, once daily (QD). (clinicaltrials.gov)
• Levin K, Daa Schroeder H, Alford FP, Beck-Nielsen H. Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes. (pubmedcentralcanada.ca)
• ABSTRACT Objective The aim of this study was to verify the effects of glycemic index (GI) on body composition, and on inflammatory and metabolic markers concentrations in patients with type 2 diabetes. (bvsalud.org)
• SAN FRANCISCO Both lifestyle and metformin help to prevent diabetes in high-risk patients over the long run researchers reported here. (diabetestalk.net)
• 11 compared aspart to regular insulin in a study reported at the The majority of the pancreas lies in a retro peritoneal patency of cystic duct and its relation to primary tumour location may be obtained by performing a Diabetes Quality of Life (DQOL) Questionnaire of a diabetes quality-of-life measure for the measures of quality of life in patients with type I and Burning sensations (especially in the evening). (diabetestalk.net)

Lipoatrophy1

• The second group is defined by a lack of preceding inflammation and a common histologic pattern of involutional lipoatrophy. (medscape.com)

Symptoms10

• In the latter category, a degree of hyperglycemia sufficient to cause pathologic and functional changes in various target tissues, but without clinical symptoms, may be present for a long period of time before diabetes is detected. (diabetesjournals.org)
• These criteria were based on recommendations of a widely cited consensus document from the National Diabetes Data Group.² The cut points were selected because they identified a group of individuals who were subsequently at risk for developing symptoms of uncontrolled hyperglycemia. (scribd.com)
• This table lists symptoms that people with this disease may have. (cdc.gov)
• For most diseases, symptoms will vary from person to person. (cdc.gov)
• People with the same disease may not have all the symptoms listed. (cdc.gov)
• Do you have more information about symptoms of this disease? (cdc.gov)
• Individuals affected with this disease present a variety of symptoms ranging from cosmetic to life-threatening complications. (mhmedical.com)
• The signs and symptoms of Type 1 diabetes usually develop quickly especially in children over a period of weeks. (bestcities.eu)
• What is a normal blood sugar reading for an 8 year old boy I don't know early symptoms of diabetes? (bestcities.eu)
• The classic symptoms of diabetes include polydipsia, and unexplained weight loss. (glowm.com)

Autoimmune diseases2

• The present invention is directed to the use of the peptide compound Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH 2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. (patentsencyclopedia.com)
• The present invention is directed to the use of the peptide compound Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pm-Phe-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. (patentsencyclopedia.com)

Severity of the underlyin1

• Thus, the degree of hyperglycemia reflects the severity of the underlying metabolic process and its treatment more than the nature of the process itself. (diabetesjournals.org)

Pancreas1

• The first group (Type I) is often used to describe the onset of diabetes, which is triggered by the inability of the pancreas to produce sufficient amounts of insulin for glucose uptake and metabolism. (hindawi.com)

Chronic4

• BACKGROUND/AIMS: Studies on non-alcoholic fatty liver disease (NAFLD) have included chronic liver damage attributed to various causes. (thedoctorsdoctor.com)
• Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease. (thedoctorsdoctor.com)
• Steatohepatitis, of either alcoholic or nonalcoholic etiologies, is ultimately diagnosed by clinical-pathologic correlation and is characterized histologically by lesions that differ from the portal-based chronic inflammation and fibrosis of most other forms of chronic liver disease. (thedoctorsdoctor.com)
• The epidemic of obesity has been paralleled by an increase in the incidence of chronic kidney disease (CKD). (asnjournals.org)

Heterogeneous group of diseases1

• Lipodystrophies are a heterogeneous group of diseases clinically characterized by a congenital or acquired loss of fat in circumscribed, partial, or diffuse areas of the body. (medscape.com)

Pancreatic3

• Leney and Tavaré [ 1 ] report that the insufficiency of insulin in Type I diabetes results from the destruction of the autoimmune response, which disrupts the pancreatic β -cells. (hindawi.com)
• Type 1 diabetes is characterized by destruction of pancreatic β-cells. (springer.com)
• Type 1 diabetes (T1D) occurs from autoimmune destruction of pancreatic β-cells, which are responsible for the secretion of insulin. (scribd.com)

Insulin secretion2

• Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. (diabetesjournals.org)
• Type 2 diabetes is characterized by combinations of decreased insulin secretion and decreased insulin sensitivity (insulin resistance). (springer.com)

Susceptibility to Type II diabe1

• There have also been reported cases in the American population of increased susceptibility to Type II diabetes due to family history and lack of cardiorespiratory fitness [ 3 ]. (hindawi.com)