Clindamycin: An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.Streptomyces: A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Fermentation: Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Erythromycin: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.Lincomycin: An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.Drug Resistance, Bacterial: The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Antibiotic Prophylaxis: Use of antibiotics before, during, or after a diagnostic, therapeutic, or surgical procedure to prevent infectious complications.Drug Resistance, Microbial: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Bacteria, AnaerobicMacrolides: A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.Bacteroides fragilis: Gram-negative bacteria occurring in the lower intestinal tracts of man and other animals. It is the most common species of anaerobic bacteria isolated from human soft tissue infections.Staphylococcus aureus: Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).Aminoglycosides: Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS.Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.Tetracycline: A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.Bacterial Infections: Infections by bacteria, general or unspecified.Staphylococcal Infections: Infections with bacteria of the genus STAPHYLOCOCCUS.Penicillins: A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)Bacteroides Infections: Infections with bacteria of the genus BACTEROIDES.Streptococcal Infections: Infections with bacteria of the genus STREPTOCOCCUS.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Lincosamides: A family of LINCOMYCIN-related glycosides that contain a pyrrolidine ring linked via an amide-bond to a pyranose moiety. Individual members of this family are defined by the arrangement of specific constituent groups on the lyncomycin molecule. Many lincosamides are ANTIBIOTICS produced by a variety STREPTOMYCES species.Cefoxitin: A semisynthetic cephamycin antibiotic resistant to beta-lactamase.Staphylococcus: A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.Drug Resistance, Multiple, Bacterial: The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Anti-Infective Agents: Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.Antibiotics, Antineoplastic: Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms.Ketolides: Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.Gram-Positive Bacteria: Bacteria which retain the crystal violet stain when treated by Gram's method.beta-Lactams: Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.Streptococcus pyogenes: A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.Bacteroides: A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Virginiamycin: A cyclic polypeptide antibiotic complex from Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. It consists of 2 major components, VIRGINIAMYCIN FACTOR M1 and virginiamycin Factor S1. It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.Penicillin Resistance: Nonsusceptibility of an organism to the action of penicillins.Azithromycin: A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.Abscess: Accumulation of purulent material in tissues, organs, or circumscribed spaces, usually associated with signs of infection.Chloramphenicol: An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)Bacterial Proteins: Proteins found in any species of bacterium.Clostridium difficile: A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.Leucomycins: An antibiotic complex produced by Streptomyces kitasatoensis. The complex consists of a mixture of at least eight biologically active components, A1 and A3 to A9. Leucomycins have both antibacterial and antimycoplasmal activities.Tobramycin: An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the PSEUDOMONAS species. It is a 10% component of the antibiotic complex, NEBRAMYCIN, produced by the same species.Cephalosporins: A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.Lactams: Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.Bacteria, AerobicStreptococcus pneumoniae: A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.Streptococcus agalactiae: A bacterium which causes mastitis in cattle and occasionally in man.Acne Vulgaris: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.Methicillin-Resistant Staphylococcus aureus: A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.Enterocolitis, Pseudomembranous: An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.Kanamycin: Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Methicillin Resistance: Non-susceptibility of a microbe to the action of METHICILLIN, a semi-synthetic penicillin derivative.Drug Utilization: The utilization of drugs as reported in individual hospital studies, FDA studies, marketing, or consumption, etc. This includes drug stockpiling, and patient drug profiles.Aza CompoundsCulture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.Fluoroquinolones: A group of QUINOLONES with at least one fluorine atom and a piperazinyl group.Streptomycin: An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.Surgical Wound Infection: Infection occurring at the site of a surgical incision.Staphylococcal Skin Infections: Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS.Oxazolidinones: Derivatives of oxazolidin-2-one. They represent an important class of synthetic antibiotic agents.Community-Acquired Infections: Any infection acquired in the community, that is, contrasted with those acquired in a health care facility (CROSS INFECTION). An infection would be classified as community-acquired if the patient had not recently been in a health care facility or been in contact with someone who had been recently in a health care facility.Vaginosis, Bacterial: Polymicrobial, nonspecific vaginitis associated with positive cultures of Gardnerella vaginalis and other anaerobic organisms and a decrease in lactobacilli. It remains unclear whether the initial pathogenic event is caused by the growth of anaerobes or a primary decrease in lactobacilli.OsteomyelitisStreptogramin B: A specific streptogramin group B antibiotic produced by Streptomyces graminofaciens and other bacteria.Cefazolin: A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.Streptococcus: A genus of gram-positive, coccoid bacteria whose organisms occur in pairs or chains. No endospores are produced. Many species exist as commensals or parasites on man or animals with some being highly pathogenic. A few species are saprophytes and occur in the natural environment.Cross Infection: Any infection which a patient contracts in a health-care institution.Thienamycins: Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.Colony Count, Microbial: Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.Gram-Negative Bacteria: Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.Methicillin: One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.Cephalexin: A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Fosfomycin: An antibiotic produced by Streptomyces fradiae.Ceftriaxone: A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Acetamides: Derivatives of acetamide that are used as solvents, as mild irritants, and in organic synthesis.Vaginal Creams, Foams, and Jellies: Medicated dosage forms for topical application in the vagina. A cream is a semisolid emulsion containing suspended or dissolved medication; a foam is a dispersion of a gas in a medicated liquid resulting in a light, frothy mass; a jelly is a colloidal semisolid mass of a water soluble medicated material, usually translucent.Pharyngitis: Inflammation of the throat (PHARYNX).Trimethoprim-Sulfamethoxazole Combination: This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.Rifampin: A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)Penicillin V: A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.Gram-Positive Bacterial Infections: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.Soft Tissue Infections: Infections of non-skeletal tissue, i.e., exclusive of bone, ligaments, cartilage, and fibrous tissue. The concept is usually referred to as skin and soft tissue infections and usually subcutaneous and muscle tissue are involved. The predisposing factors in anaerobic infections are trauma, ischemia, and surgery. The organisms often derive from the fecal or oral flora, particularly in wounds associated with intestinal surgery, decubitus ulcer, and human bites. (From Cecil Textbook of Medicine, 19th ed, p1688)Streptogramins: A class of natural cyclic peptide antibiotics produced by certain subspecies of STREPTOMYCES. They include two structurally unrelated components, STREPTOGRAMIN GROUP A and STREPTOGRAMIN GROUP B, which generally act synergistically to inhibit bacterial growth.Clostridium Infections: Infections with bacteria of the genus CLOSTRIDIUM.Sarcina: A genus of gram-positive, anaerobic bacteria whose organisms divide in three perpendicular planes and occur in packets of eight or more cells. It has been isolated from soil, grains, and clinical specimens.Pseudomonas aeruginosa: A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.Cloxacillin: A semi-synthetic antibiotic that is a chlorinated derivative of OXACILLIN.Cephalothin: A cephalosporin antibiotic.Keratolytic Agents: Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.Moxalactam: Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.beta-Lactamases: Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.Amoxicillin: A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.Roxithromycin: Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.Doxycycline: A synthetic tetracycline derivative with similar antimicrobial activity.Imipenem: Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.Piperacillin: Semisynthetic, broad-spectrum, AMPICILLIN derived ureidopenicillin antibiotic proposed for PSEUDOMONAS infections. It is also used in combination with other antibiotics.Tetracyclines: Closely congeneric derivatives of the polycyclic naphthacenecarboxamide. (Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1117)Genes, Bacterial: The functional hereditary units of BACTERIA.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Fusidic Acid: An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.Floxacillin: Antibiotic analog of CLOXACILLIN.Amikacin: A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.Chemistry: A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.Chemical Phenomena: The composition, conformation, and properties of atoms and molecules, and their reaction and interaction processes.QuinolinesCephamycins: Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms.Cefotaxime: Semisynthetic broad-spectrum cephalosporin.Carbenicillin: Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.Enterococcus: A genus of gram-positive, coccoid bacteria consisting of organisms causing variable hemolysis that are normal flora of the intestinal tract. Previously thought to be a member of the genus STREPTOCOCCUS, it is now recognized as a separate genus.Miocamycin: A macrolide antibiotic that has a wide antimicrobial spectrum and is particularly effective in respiratory and genital infections.Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.Methyltransferases: A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1.
... intact blood group substance with suboptimal glucose, or completely hydrolyzed blood group substance. The blood group A- ... The selection effect of antibiotics on C. tertium may occur in cases where patients have had prior exposure to β-lactam ... clindamycin; and metronidazole; but it is susceptible to vancomycin, trimethoprim-sulfamethoxazole, and ciprofloxacin. ... It has been established that C. tertium elaborates enzymes directed against blood group A antigen in the presence of ...
... a course of oral antibiotics is often prescribed,. Common antibiotics used are from the β-lactam antibiotic group, clindamycin ... Also immediate treatment avoids overuse of antibiotics (preventing antibiotic resistance). However, surgery is sometimes ... delayed in an area of acute infection, with the help of pain relief and antibiotics, for the following reasons: Reduces the ...
Other antibiotics common for the treatment of STDs include clindamycin or trinidazole. The word leukorrhea comes from Greek ... Leukorrhea is also caused by trichomonads, a group of parasitic protozoan, specifically Trichomonas vaginalis. Common symptoms ... Treatment may include antibiotics, such as metronidazole. ...
The antibiotics chloramphenicol, clindamycin, and tetracycline have been known to inactivate aminoglycosides in general by ... Another group of beta-lactams, the cephalosporins, can increase the nephrotoxicity of aminoglycoside as well as randomly ... "The Journal of Antibiotics. 25 (12): 695-708. doi:10.7164/antibiotics.25.695. ISSN 0021-8820. PMID 4568692. Archived from the ... Amikacin evades attacks by all antibiotic-inactivating enzymes that are responsible for antibiotic resistance in bacteria, ...
Despite the emergence of antibiotics as a treatment for group A β-hemolytic streptococcus, infection of GAS is an increasing ... Treatment with ampicillin/sulbactam, amoxicillin/clavulanic acid, or clindamycin is appropriate if deep oropharyngeal abscesses ... Group A Streptococcus Working Group (2004). "Interim UK guidelines for management of close community contacts of invasive group ... "Group A Strep". CDC.gov. CDC. Retrieved 7 December 2014. "Group A Strep". CDC.gov. CDC. Retrieved 7 December 2014. Good MF, ...
A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a ... Lincomycin is an antibiotic classified as a constituent of the lincosamide group, which typically feature a 6,8-dideoxy-6- ... Condensation of the carboxyl group on the propylproline with the amine group of the methylthiolincosamide via an amide bond is ... 42 (3): 475-8. doi:10.7164/antibiotics.42.475. PMID 2708143. Kuo MS, Yurek DA, Coats JH, Chung ST, Li GP (November 1992). " ...
... appear to be higher than with some groups of antibiotics such as cephalosporins but lower than with others such as clindamycin ... Rates of side effects appear to be higher than some groups of antibiotics such as cephalosporins but lower than others such as ... Compared to other antibiotics some studies find a higher rate of side effects while others find no difference. In trials most ... Ciprofloxacin is an antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra ...
This group includes: Chloramphenicol Clindamycin Ethambutol Lincosamides Macrolides Nitrofurantoin Novobiocin Oxazolidinone ... Bacteriostatic antibiotics limit the growth of bacteria by interfering with bacterial protein production, DNA replication, or ... However, there is not always a precise distinction between them and bactericidal antibiotics; high concentrations of some ... Depending on their application, bacteriostatic antibiotics, disinfectants, antiseptics and preservatives can be distinguished. ...
This is why adding an antibiotic like clindamycin, which acts ribosomally, kills some of the bacterial and returns them to the ... such as with Group A Strep), bacteria may be in the stationary phase of growth. In this instance since no bacteria are actively ... Ikeda, Y; Fukuoka, Y; Motomura, K; Yasuda, T; Nishino, T (January 1990). "Paradoxical activity of beta-lactam antibiotics ... Stevens, DL; Gibbons, AE; Bergstrom, R; Winn, V (July 1988). "The Eagle effect revisited: efficacy of clindamycin, erythromycin ...
Usually treatment is with an antibiotic, such as clindamycin or metronidazole. These medications may also be used in the second ... Rates vary considerably between ethnic groups within a country. While BV like symptoms have been described for much of recorded ... Treatment is typically with the antibiotics metronidazole or clindamycin. They can be either given by mouth or applied inside ... When clindamycin is given to pregnant women symptomatic with BV before 22 weeks of gestation the risk of pre-term birth before ...
In general, penicillin is the antibiotic of choice for treatment of GBS infections. Erythromycin or clindamycin should not be ... UK Group B Strep Association] UK  Ontario Midwives Group B Strep International CDC-Group B Strep (GBS) Group B Strep ... antibiotics for prevention and treatment" states: "Intrapartum Antibiotic Prophylaxis should be offered if group B ... PHLS Group B Streptococcus Working Group. (2004). "Group B streptococcal disease in UK and Irish infants younger than 90 days ...
... prophylactic antibiotics may also be given prior to dental procedures such as penicillin or clindamycin for penicillin allergic ... HACEK group of microorganisms and fungi are seen less frequently in North America. The viridians group include S.oralis, S. ... High-dose antibiotics are administered by the intravenous route to maximize diffusion of antibiotic molecules into vegetation(s ... Treatment is generally with intravenous antibiotics. The choice of antibiotics is based on the blood cultures. Occasionally ...
Antibiotics are limited in their ability to prevent these infections since there are a variety of subtypes of group A ... In those cases it is appropriate to choose clindamycin or erythromycin instead. Tonsillectomy, although once a reasonable ... One method is long term use of antibiotics to prevent future group A streptococcal infections. This method is only indicated ... Scarlet fever is a disease which can occur as a result of a group A streptococcus (group A strep) infection. The signs and ...
... is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections ... It is obtained by 7(S)-chloro-substitution of the 7(R)-hydroxyl group of lincomycin. The synthesis of clindamycin was first ... The topically used clindamycin phosphate is a phosphate-ester prodrug of clindamycin. Clindamycin has a primarily ... Clindamycin University of Michigan. Retrieved July 31, 2009 Wilson, Daniel N. "Ribosome-targeting antibiotics and mechanisms of ...
If the tonsillitis is caused by group A streptococcus, then antibiotics are useful, with penicillin or amoxicillin being ... who fail penicillin therapy may respond to treatment effective against beta-lactamase producing bacteria such as clindamycin or ... The diagnosis of group A beta-hemolytic streptococcus (GABHS) tonsillitis can be confirmed by culture of samples obtained by ... 2006). "Group A streptococcal infections". Red Book: 2006 Report of the Committee on Infectious Diseases (Red Book Report of ...
Antibiotic of quinolone group. clamoxyquine - Antiparasitic to treat salmonids for infection with the myxozoan parasite, ... clenbuterol - A decongestant and bronchodilator used for the treatment of recurrent airway obstruction in horses clindamycin - ... cefovecin - Cephalosporin-class antibiotic used to treat skin infections in dogs and cats. cefpodoxime - Antibiotic cephalexin ... clavamox antibiotic- oral, used to treat skin and other infections. clavaseptin oral crushed and mixed with food or a treat for ...
... endometritis is excessive and in uncomplicated cases can resolve after 2 weeks of clindamycin and gentamicin IV antibiotic ... Group B Streptococcus), Mycoplasma hominis, tuberculosis, and various viruses. Most of these agents are capable of causing ... There is not enough evidence for the use of prophylactic antibiotics to prevent endometritis after manual removal of placental ... Pyometra is treated with antibiotics, according to culture and sensitivity. Maternal death Puerperal fever "endometritis" at ...
Subgroup G01 is part of the anatomical group G Genito-urinary system and sex hormones. Codes for veterinary use (ATCvet codes) ... combinations QG01AA90 Tetracycline QG01AA91 Gentamicin QG01AA99 Antibiotics, combinations G01AB01 Acetarsol G01AC01 ... G01AA05 Chloramphenicol G01AA06 Hachimycin G01AA07 Oxytetracycline G01AA08 Carfecillin G01AA09 Mepartricin G01AA10 Clindamycin ...
... and clindamycin, causes the normal bacterial flora of the bowel to be altered. In particular, when the antibiotic kills off ... In 2005, molecular analysis led to the identification of the C. difficile strain type characterized as group BI by restriction ... Antibiotic treatment of CDIs may be difficult, due both to antibiotic resistance and physiological factors of the bacteria ( ... C. difficile does not often occur in people who are not taking antibiotics so limiting use of antibiotics decreases the risk. ...
"Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae ... Second-line agents include macrolides and clindamycin, although increasing resistance, due to both efflux and target ... large-colony-forming group C and group G streptococcus of human origin, and certain large-colony-forming group C, G and L ... the S.anginosus group being VP positive. Streptococcus equi contains Lancefield group C, and Streptococcus canis harbours group ...
A quinolone antibiotic is any member of a large group of broad-spectrum bactericides that share a bicyclic core structure ... clindamycin, sulfonamides, or vancomycin. Fluoroquinolones prolong the heart's QT interval by blocking voltage-gated potassium ... Overuse of these antibiotics will eventually render them useless for treating antibiotic-resistant infections, for which broad- ... Susceptible groups of patients, such as children and the elderly, are at greater risk of adverse reactions during therapeutic ...
... these exotoxins are the bacterial equivalent of antibiotics such as clindamycin.) Some exotoxins act directly at the ribosome ... Another group of intracellular toxins is the AB toxins. The 'B'-subunit (binding) attaches to target regions on cell membranes ... of this A-subunit activity is called ADP-ribosylation in which the A-subunit catalyzes the addition of an ADP-ribose group onto ...
Zimbelman J, Palmer A, Todd J (1999). "Improved outcome of clindamycin compared with beta-lactam antibiotic treatment for ... Jim Henson, d. 1990, contracted the syndrome due to group A streptococcal infection and subsequently died from it. Nan C. ... Antibiotic treatment should cover both S. pyogenes and S. aureus. This may include a combination of cephalosporins, penicillins ... The addition of clindamycin or gentamicin reduces toxin production and mortality. With proper treatment, people usually recover ...
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"Clindamycin" (PDF). Davis. 2017. Retrieved March 24, 2017.. [permanent dead link] *^ "Symptoms and Complications". Centers for ... Competence in S. pneumoniae is induced by DNA-damaging agents such as mitomycin C, fluoroquinolone antibiotics (norfloxacin, ... "Critical decline in pneumococcal disease and antibiotic resistance in South Africa". NICD. Retrieved 20 July 2015.. ... This condition is called pneumonia. It is susceptible to clindamycin. ...
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- Which antibiotics are best for tooth infection cephalexin or clindamycin? (drugs.com)
- What antibiotic is good for tooth infection? (drugs.com)
- This means that if you get a bacterial infection again, clindamycin may not work to treat it. (medicalnewstoday.com)
- Antibiotics are most often prescribed as a precaution since drains can be a source for infection by creating open channels to outside contaminants. (clinicaltrials.gov)
- The investigators hypothesize that the use of 24-hour perioperative antibiotics in TE or AF based immediate breast reconstruction with closed suction drainage, does not result in an increased infection rate compared to prolonged postoperative antibiotic administration. (clinicaltrials.gov)
- Clindamycin might be used to prevent an infection in the heart before a dental procedure, too, especially for people who may be allergic to or unable to take penicillin. (everydayhealth.com)
- In this retrospective cohort study, patients were included who received clindamycin-rifampin combination therapy to treat a periprosthetic hip or knee infection by Staphylococcus aureus or coagulase-negative staphylococci. (biomedcentral.com)
- Combined therapy with clindamycin and rifampin is a safe, well tolerated and effective regimen for the treatment of staphylococcal periprosthetic infection. (biomedcentral.com)
- In these cases, many clinicians begin empiric therapy with amoxicillin, but its spectrum of activity is lacking, because children in this group who do not have nonviral pneumonia usually have an infection caused by S pneumoniae and Mycoplasma species. (medscape.com)
- Group B streptococcal (GBS) infection remains the most common cause of neonatal early-onset sepsis and a significant cause of late-onset sepsis among young infants. (aappublications.org)
- Because of the risk of antibiotic -associated pseudomembranous colitis , as described in the BOXED WARNING , before selecting clindamycin the physician should consider the nature of the infection and the suitability of less toxic alternatives (e.g., erythromycin ). (rxlist.com)
- In patients with prosthetic joint implants, a January 2015 ADA clinical practice guideline , based on a 2014 systematic review states, "In general, for patients with prosthetic joint implants, prophylactic antibiotics are not recommended prior to dental procedures to prevent prosthetic joint infection. (ada.org)
- When a physician routinely prescribes antibiotics for viral infections, either in the hope of staving off a secondary bacterial infection or to placate a patient, another opportunity is created for resistant bacteria to survive while killing off both the pathogenic bacteria still sensitive to the antibiotic and normal gut flora as well. (hubpages.com)
- As the second most reportable bacterial infection, gonorrhea is becoming a greater public health issue due to its increasing resistance to antibiotics. (hubpages.com)
- CRE is responsible for the largest U.S. outbreak of antibiotic resistant infection reported in January 2014. (hubpages.com)
- However to determine the likely impact and the optimal strategy of antibiotic administration the colonization prevalence and neonatal infection rate for GBS in the target population should be known. (biomedcentral.com)
- Therefore, we systematically identified RCT and cohort studies on the issue published up to April 2016, and carried out a meta-analysis to explore the potential effect of intrapartum antibiotics for maternal GBS colonization on neonatal adverse outcomes (including GBS colonization, infection, and mortality). (frontiersin.org)
- Clindamycin is an antibiotic and treats infection. (rxwiki.com)
- Preseptal cellulitis is an eye infection which is commonly found in children of age group 4-7. (amazonaws.com)
- S. pyogenes TSS is defined as any group A beta-hemolytic streptococci (GABHS) infection associated with shock and organ failure. (merckmanuals.com)
- After consultation with a pediatric infectious disease specialist, however, the antibiotics were discontinued because of concerns about possible infection with other bacteria that had not been detected by culture and rapid tests. (contemporarypediatrics.com)
- Unlike group C beta-hemolytic streptococcal bacteremia, group G beta-hemolytic streptococcal bacteremia is not a zoonotic infection in Hong Kong. (asm.org)
- Which of these clinical scenarios has NOT been associated with perinatal group B strep infection in the perinate? (groupbstrepinternational.org)
- Antibiotic clindamycin cost will not treat a viral infection such as the flu or a common cold. (alpine-club.org.uk)
- The use of intrapartum antibiotics to prevent early-onset group B streptococcal (EOGBS) infection has left pediatricians in a quandary about the appropriate evaluation and treatment of infants at risk for this infection. (aappublications.org)
- Exposure to antibiotics during labor did not change the clinical spectrum of disease or the onset of clinical signs of infection within 24 hours of birth for term infants with EOGBS infection. (aappublications.org)
- A 48-hour stay is not required to monitor asymptomatic term infants exposed to intrapartum antibiotics for onset of GBS infection. (aappublications.org)
- 3,4 Attempts to decrease the incidence and severity of this potentially lethal infection have focused on preventing transmission from mother to infant during labor by administration of intrapartum antibiotics. (aappublications.org)
- We conducted a retrospective chart review of infants with EOGBS infection born from 1988 through 1996 in Southern California Kaiser Permanente Hospitals to evaluate the relationship between intrapartum antibiotic use and the clinical signs of infection and timing of onset of these signs in term infants with EOGBS infections. (aappublications.org)
- Soft tissue infections are typically produced by bacterial infection from Staphylococcus aureus or group A beta-hemolytic streptococci . (neurologyadvisor.com)
- In babies given antibiotics because of risk factors for infection or clinical indicators of possible infection, consider stopping the antibiotics at 36 hours if: the blood culture is negative, and the initial clinical suspicion of infection was not strong, and the baby's clinical condition is reassuring with no clinical indicators of possible infection, and the levels and trends of C-reactive protein concentration are reassuring. (nice.org.uk)
- Although C. difficile infection is commonly associated with antibiotic use, the precise alterations to the microbiota associated with this loss in function are unknown. (asm.org)
- Whether you ve had a sinus infection or ear infection, a UTI or a cut that turned oozy and red, chances are you ve taken antibiotics. (care2.com)
- So not only could the bacterium causing your infection outsmart the antibiotic you re taking, but also you could transmit it to someone who isn t even taking an antibiotic. (care2.com)
- One possible reason: Doctors routinely write an RX for antibiotics even if they aren t sure a patient has a bacterial infection. (care2.com)
- When that happens, the infection can recur, prompting the doctor to prescribe another antibiotic to knock it out. (care2.com)
- Clindamycin works by killing or stopping the growth of bacteria causing your infection. (nps.org.au)
- Any group A streptococcal infection may be associated with strep TSS, though necrotizing infections of the fascia and muscle are most common. (renalandurologynews.com)
- Persistent AOM occurs when there are persistent features of a middle-ear infection during antibiotic treatment or when a relapse occurs within 1 month of completion of therapy. (uspharmacist.com)
- People who are at particular risk of developing MRSA are those who are in close contact with someone with a MRSA infection, have taken antibiotics during the past month, and have a history of a MRSA infection. (skinsight.com)
- It is important to finish all of the antibiotics, even if the infection appears to be healed. (skinsight.com)
- Irrigation with a combined G + C antibiotic irrigation significantly reduces the incidence of surgical site infection after OVHR with mesh. (ingentaconnect.com)
- Different types of antibacterials (except drugs included in the group of beta-lactam antibiotics) can be used to treat resistant staph infection. (ahefv.com)
- When treating MRSA, it is important to choose antibiotics that work, help quickly get rid of the infection and prevent transmission of dangerous bacteria from an infected person to healthy people. (ahefv.com)
- All the listed antibiotics for MRSA really work and help quickly to stop the development of infection. (ahefv.com)
- That is why dentists prescribe antibiotics to prevent the spread of the infection. (allhealthsite.com)
- Sometimes the dentist prescribes antibiotics to get the infection under control before treating the abscessed tooth. (allhealthsite.com)
- Abscessed tooth is a result of bacterial infection, so one of the best ways to combat it is through the use antibiotics like amoxicillin, metronidazole, clindamycin, co-amoxiclav, and penicillin. (allhealthsite.com)
- Clindamycin works by stopping bacteria from multiplying. (medicalnewstoday.com)
- Clindamycin is an antibiotic that stops the growth of acne-causing bacteria. (thefreelibrary.com)
- Clindamycin changes the balance of microorganisms in your intestines, allowing growth of bacteria called Clostridium difficile (C. difficile) . (everydayhealth.com)
- Antibiotics also may be prescribed to kill bacteria and reduce inflammation. (encyclopedia.com)
- Metronidazole is an imidazole ring-based antibiotic active against various anaerobic bacteria and protozoa. (medscape.com)
- Antibiotics, those wonder drugs of years past, have been misused and overused leading to bacteria with the ability to withstand the strongest medications doctors have to throw at them. (hubpages.com)
- When a patient does not complete a course of antibiotics, those bacteria remaining are less sensitive to that agent. (hubpages.com)
- Bringing a new antibiotic to market can easily cost up to $1 billion for something that can only be used for short periods of time and to which bacteria will eventually become resistant. (hubpages.com)
- To reduce the development of drug-resistant bacteria and maintain the effectiveness of clindamycin in 5% dextrose injection and other antibacterial drugs, clindamycin in 5% dextrose injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
- Erythromycins, also called macrolides, are a group of antibiotics , medicines that kill bacteria or prevent their growth. (healthofchildren.com)
- First, many strains of bacteria are becoming resistant to even our strongest antibiotics and are causing deadly infections. (healthimpactnews.com)
- According to a landmark "Antibiotic Resistance Threat Report" published by the CDC earlier this year, 2 million American adults and children become infected with antibiotic-resistant bacteria each year, and at least 23,000 of them die as a direct result of those infections. (healthimpactnews.com)
- Hospitals here are not required to report outbreaks of antibiotic-resistant bacteria, unlike in the EU where they are at least making efforts to track them. (healthimpactnews.com)
- ESBLs are enzymes produced by certain types of bacteria, which renders the bacteria resistant to the antibiotics used to treat them. (healthimpactnews.com)
- However, little is known about the relative importance of the various species and thus the source of bacteria causing bacteremia, the usefulness of commercial kits in identifying the species, and the factors that determine the outcome for patients with group G beta-hemolytic streptococcal bacteremia. (asm.org)
- This antibiotic is able to kill bacteria by stopping the production of the vital proteins the bacteria needs to survive. (dutypharmacy.com)
- People could be exposed to antibiotic-resistant bacteria from breathing the air from concentrated swine feeding facilities, according to researchers at the Johns Hopkins Bloomberg School of Public Health. (jhsph.edu)
- They detected bacteria resistant to at least two antibiotics in air samples collected from inside a large-scale swine operation in the Mid-Atlantic region of the United States. (jhsph.edu)
- Until now, little research has been conducted regarding the presence of antibiotic-resistant bacteria in the air within industrial swine facilities. (jhsph.edu)
- The study adds to the understanding of various pathways in which humans can be exposed to antibiotic-resistant bacteria, such as consumption of retail pork products and contact with or ingestion of soil, surface water and groundwater near production operations. (jhsph.edu)
- Eating retail pork products is not the only pathway of exposure for the transfer of antibiotic-resistant bacteria from swine to humans. (jhsph.edu)
- Chapin explained that the use of antibiotics in industrial animal production has a significant impact on the emergence of antibiotic-resistant bacteria that threaten human health. (jhsph.edu)
- The airborne bacteria samples that were found to be multidrug-resistant were: Enterococcus, coagulase negative staphylococci and viridans group streptococci. (jhsph.edu)
- The researchers believe workers at concentrated animal feeding operations are at greatest risk for airborne exposure to antibiotic-resistant bacteria. (jhsph.edu)
- These research findings add another piece to our understanding of human exposure to antibiotic-resistant bacteria," said Kellogg Schwab, PhD, assistant professor in the Bloomberg School of Public Health's Department of Environmental Health Sciences and the study's corresponding author. (jhsph.edu)
- Finding and documenting the multiple environmental pathways of exposure are critical to finding solutions to the growing, serious problem of antibiotic-resistant bacteria in humans. (jhsph.edu)
- But precisely because antibiotics are the go-to drug for doctors and patients alike, the medications are in danger of losing their ability to kill bacteria. (care2.com)
- For decades, pharmaceutical companies routinely developed new antibiotics that enabled us to stay one step ahead of antibiotic resistant bacteria. (care2.com)
- Because the more you or a family member or friend use antibiotics, the greater the likelihood bacteria will become resistant to one or more of the drugs. (care2.com)
- According to WHO, antibiotic resistance to bacteria that cause life-threatening infections such as pneumonia, bloodstream infections and infections in newborns and ICU patients has spread to all regions of the world. (care2.com)
- Excessive use of penicillin antibiotics over the years has led to the development of stronger strains of bacteria that are no longer killed by penicillin-type antibiotics. (skinsight.com)
- Methicillin-resistant Staphylococcus aureus (MRSA) is a strain of staph bacteria that is resistant to penicillin and standard penicillin-related antibiotics. (skinsight.com)
- This helps to specifically identify the bacteria and choose the correct antibiotics. (skinsight.com)
- Clindamycin oral capsule is a prescription medication that's available as the brand-name drug Cleocin. (medicalnewstoday.com)
- What Is Clindamycin (Cleocin)? (everydayhealth.com)
- Clindamycin is the generic name of the prescription drug Cleocin, which is an antibiotic used to treat certain serious bacterial infections. (everydayhealth.com)
- Clindamycin was first approved by the Food and Drug Administration (FDA) under the brand name Cleocin in 1970, and was manufactured by Pharmacia and Upjohn (now Pfizer). (everydayhealth.com)
- It comes in lotion, cream, or gel form under the name Cleocin T or clindamycin phosphate. (everydayhealth.com)
- CLEOCIN PHOSPHATE Sterile Solution in vials contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. (rxlist.com)
- CLEOCIN PHOSPHATE IV Solution in the GALAXY plastic container for intravenous use is composed of clindamycin phosphate equivalent to 300, 600 and 900 mg of clindamycin premixed with 5% dextrose as a sterile solution. (rxlist.com)
- What are the precautions when taking clindamycin (Cleocin I.V. (rxlist.com)
- Cleocin is prescribed for the treatment of bacterial infections provoked by anaerobic microorganisms that are sensitive to its active component - Clindamycin. (dutypharmacy.com)
- Cleocin, or Clindamycin, as it is also known, is a semi-synthetic lincosamide antibiotic that contains Clindamycin hydrochloride, a hydrated hydrochloride salt of clindamycin. (dutypharmacy.com)
- Join the ' Infections ' group to help and get support from people like you. (drugs.com)
- Our support group for Infections has 1,499 questions and 851 members. (drugs.com)
- Clindamycin-resistant strains have caused more than 40% of In adults, GBS causes infections among pregnant women, GBS infections, limiting prevention and treatment options for older adults, and people with certain medical conditions, people with severe penicillin allergy. (cdc.gov)
- However, clindamycin-resistant germs cause v asiv more than 40% of GBS infections. (cdc.gov)
- Clindamycin is used to treat certain bacterial infections. (medicalnewstoday.com)
- WHO convened a Guideline Development Group (GDG) meeting on recommendations on prevention and treatment of maternal peripartum infections in September 2015, where this recommendation was developed. (who.int)
- Therefore, your doctor should only prescribe clindamycin for serious infections that other drugs won't treat. (everydayhealth.com)
- Amikacin is an antibiotic used for a number of bacterial infections . (wikipedia.org)
- No infectious complications occurred in the moxalactam group whereas five infections occurred in four patients in the gentamicin plus clindamycin group (p less than 0.05). (biomedsearch.com)
- What are the IDSA guidelines for the treatment of group A streptococcal (GAS) infections? (medscape.com)
- Pathogenesis of group A streptococcal infections. (medscape.com)
- The new CSA guideline clearly states that for most patients, prophylactic antibiotics are not indicated before dental procedures to prevent [prosthetic joint infections]. (ada.org)
- Because clindamycin in 5% dextrose injection therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the INDICATIONS AND USAGE section. (nih.gov)
- However, macrolide and lincosamide antimicrobial drugs, such as erythromycin and clindamycin, are often used to treat GBS infections in patients allergic or suspected to be allergic to β-lactam drugs. (cdc.gov)
- Clindamycin is a prescription medication used to treat acne and vaginal infections. (rxwiki.com)
- Clindamycin can make erythromycin less effective and usually these medications should not be combined, especially when treating serious infections. (rxwiki.com)
- A trend towards reduced early-onset neonatal sepsis and reduced maternal infections in the late labour induction group was found in a sub-group analysis. (who.int)
- These antibiotics were selected initially for their broad-spectrum coverage of infections related to the oropharynx. (contemporarypediatrics.com)
- Comparative effectiveness of antibiotic treatment strategies for pediatric skin and soft-tissue infections. (alpine-club.org.uk)
- 14,15 Given that 10% to 25% of pregnant women may be treated with antibiotics during labor, 16 decisions about the evaluation and treatment of infants at risk for GBS infections affect a large number of newborns and may have substantial implications for hospital expenditures and resource allocation. (aappublications.org)
- Using antibiotics in animals can decrease the effectiveness of the same antibiotics used to combat human infections. (jhsph.edu)
- All of these drugs (or their human drug counterparts) are important antibiotics in the treatment of human infections. (jhsph.edu)
- Ciprofloxacin is an antibiotic used to treat a number of bacterial infections. (dbpedia.org)
- For some infections it is used in addition to other antibiotics. (dbpedia.org)
- Clinical practice guidelines recommend a topical antibiotic for 5 to 7 days when treating uncomplicated impetigo infections with limited and localized lesions. (cfp.ca)
- however, resistance still occurs with overuse, and topical antibiotics should be reserved for skin infections, like impetigo, and not for noninfectious scratches or rashes. (cfp.ca)
- According to the Centers for Disease Control and Prevention (CDC), more than two million Americans develop antibiotic-resistant infections every year and at least 23,000 die. (care2.com)
- Clindamycin will not work against viral infections such as colds or flu. (nps.org.au)
- if you take medicines, which can impair hearing, especially aminoglycosides (group of medicine to treat some infections). (medicines.org.uk)
- Non-group A streptococci have also been implicated from mild to serious infections. (antimicrobe.org)
- This chapter discusses the antimicrobial treatment of pyogenic groups C and G, and the VG S. It will not discuss the treatment of infections caused by S. pyogenes . (antimicrobe.org)
- While resistant to penicillin and penicillin-related antibiotics, most CA-MRSA infections can be successfully treated with many other antibiotics. (skinsight.com)
- So we wanted to target a group of elementary school children since they are really the primary population that gets strep infections. (learner.org)
- It should be noted that about half of all drugs used to treat bacterial infections are beta-lactam antibiotics. (ahefv.com)
- Therefore, to choose antibiotics for MRSA is much more difficult than for the treatment of other types of bacterial infections. (ahefv.com)
- The introduction of intrapartum antibiotics in the developing world could reduce the number of infants who die from neonatal sepsis each year. (biomedcentral.com)
- Some 30% of parturients with at least one risk factor for neonatal disease received intrapartum antibiotics. (diva-portal.org)
- The use of intrapartum antibiotics was limited in parturients with obstetric risk factors for early onset group B streptococcal disease. (diva-portal.org)
- All of the infants exposed to intrapartum antibiotics became ill within the first 24 hours of life. (aappublications.org)
- A combination of clindamycin and gentamicin is recommended for the treatment of postpartum endometritis. (who.int)
- In the majority of studies that demonstrated benefits of clindamycin and gentamicin over other regimens, clindamycin was administered as 600 mg IV every six to eight hours, and gentamicin was administered as 1-1.5 mg/kg or 60-80 mg IV or IM every eight hours. (who.int)
- A prospective randomized study of moxalactam versus gentamicin and clindamycin in penetrating abdominal trauma. (biomedsearch.com)
- We conducted a randomized, prospective study of moxalactam versus gentamicin plus clindamycin in 42 patients with penetrating abdominal trauma. (biomedsearch.com)
- Patients were randomized to receive intravenously either 2 grams of moxalactam every 12 hours or 80 milligrams of gentamicin every eight hours and 600 milligrams of clindamycin every six hours. (biomedsearch.com)
- Twenty patients received moxalactam and 22 received gentamicin plus clindamycin. (biomedsearch.com)
- The total pharmacy cost of a five day course of moxalactam plus a single dose of vitamin K is $204.67 compared with $226.00 for a similar course of gentamicin plus clindamycin. (biomedsearch.com)
- moxalactam is safe in the doses used when combined with vitamin K, and 3, moxalactam is more cost-effective than gentamicin plus clindamycin dual antibiotic therapy. (biomedsearch.com)
- Patients were divided into three groups, receiving no antibiotic irrigation (Grp 1, n = 260), gentamicin alone (Grp 2, n = 263), or gentamicin + clindamycin (G + C) irrigation (Grp 3, n = 299). (ingentaconnect.com)
- Almost all antibiotics , including clindamycin, can cause Clostridium difficile-associated diarrhea . (medicalnewstoday.com)
- Clostridium tertium bacteremia can cause fever, and directed antibiotic therapy is indicated. (wikipedia.org)
- Clostridium difficile - associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin in 5% dextrose injection and may range in severity from mild diarrhea to fatal colitis. (nih.gov)
- Clostridium difficile is the causative agent of antibiotic-associated diarrhea and pseudomembranous colitis, diseases generally associated with exposure to antibiotics. (asm.org)
- This drug is also not appropriate for patients with certain intestinal problems, such as Crohn disease, antibiotic-associated colitis, ulcerative colitis, Clostridium difficile-associated diarrhea, and others. (dutypharmacy.com)
- Detection of antibiotic resistance toxigenic Clostridium difficile in processed retail lettuce Han, Yi;King, Joan;Janes, Marlene E 2018-03-01 00:00:00 Objectives: Clostridium difficile is the major cause of infectious diarrhoea in humans after antimicrobial treatment. (deepdyve.com)
- These enzymes methylate the bacterial ribosome at the binding site for macrolide, lincosamide, and streptogramin B (MLS B ) antibiotics, thus inhibiting antibiotic activity. (asm.org)
- Erythromycin is a member of the macrolide-lincosamide-streptogramin B (MLS) group of protein synthesis inhibitors ( 11 , 16 ). (asm.org)
- Plastic surgery patients without closed suction drainage devices are usually not placed on prolonged postoperative antibiotics. (clinicaltrials.gov)
- Using the above data and the current protocol, the investigators will investigate the optimal antibiotic discontinuation period for these patients. (clinicaltrials.gov)
- Currently at Stony Brook University Medical Center, patients normally receive 24 hours of IV Cefazolin, followed by postoperative antibiotic prescription for Cefadroxil. (clinicaltrials.gov)
- A study by Tagarro et al that included 60 randomized children with community-acquired pneumonia and pleural effusion reported that patients receiving dexamethasone along with antibiotics had a shorter time to recovery than the placebo group. (medscape.com)
- In patients who require a systemic antibiotic, evidence suggests that the newer regimen of 20-50 mg q12h of doxycycline is as effective as the older regimen of 100 mg of doxycycline. (medscape.com)
- Cure rate was 78% (14/18) in the DAIR patients and 94% (17/18) in the revision group. (biomedcentral.com)
- Five patients (14%) discontinued clindamycin-rifampin due to side effects. (biomedcentral.com)
- Of the 31 patients completing the clindamycin-rifampin regimen 29 patients (94%) were cured. (biomedcentral.com)
- For those without hollow viscus injury, only those patients receiving a minimum of three days of antibiotics were evaluated. (biomedsearch.com)
- A single intramuscular dose of 10 milligrams of vitamin K was also administered to all patients in the moxalactam group. (biomedsearch.com)
- Eight patients in each group sustained injuries to the small intestine or colon, or both. (biomedsearch.com)
- The selection effect of antibiotics on C. tertium may occur in cases where patients have had prior exposure to β-lactam antibiotics. (wikipedia.org)
- CDAD must be considered in all patients who present with diarrhea following antibiotic use. (rxlist.com)
- After intramuscular injection of clindamycin phosphate, peak concentrations of active clindamycin are reached within 3 hours in adults and 1 hour in pediatric patients. (nih.gov)
- Serum concentrations of clindamycin can be maintained above the in vitro minimum inhibitory concentrations for most indicated organisms by administration of clindamycin phosphate every 8 to 12 hours in adults and every 6 to 8 hours in pediatric patients, or by continuous intravenous infusion. (nih.gov)
- however, the serum elimination half-life of active clindamycin is about 3 hours in adults and 2½ hours in pediatric patients. (nih.gov)
- In the eczema patients, scores on a scale used to measure pruritus were reduced by between 24 and 33 per cent (depending on the dose given) one week after treatment with CIM331, compared to a nine per cent reduction in the placebo group. (bad.org.uk)
- The test group consisted of 25 patients with tonsillectomy. (springer.com)
- The control group included 25 patients with otorhinolarynologic surgery without involvement of the oral cavity. (springer.com)
- Little is known about the relative importance of the four species of Lancefield group G beta-hemolytic streptococci in causing bacteremia and the factors that determine the outcome for patients with group G beta-hemolytic streptococcal bacteremia. (asm.org)
- From 1997 to 2000, 75 group G beta-hemolytic streptococcal strains were isolated from the blood cultures of 66 patients. (asm.org)
- Fifty-eight patients (88%) had community-acquired group G streptococcal bacteremia. (asm.org)
- It has been reported that diabetes mellitus (DM), malignancy, cardiovascular disease, bone and joint diseases, and cirrhosis are the major underlying diseases in patients with group G beta-hemolytic streptococcal bacteremia ( 2 , 8 , 10 , 16 , 19 ). (asm.org)
- The cure rates for TMP-SMX and clindamycin were similar among patients who had cellulitis as the sole lesion type. (alpine-club.org.uk)
- The data described below reflect exposure to Clindesse (clindamycin phosphate) in 368 patients. (rxlist.com)
- All patients received 100 mg clindamycin phosphate cream intravaginally in a single dose. (rxlist.com)
- Of the 368 women treated with a single dose of Clindesse (clindamycin phosphate) , 1.6% of the patients discontinued therapy due to adverse reactions. (rxlist.com)
- Adverse reactions occurred in 126 of 368 patients (34%) treated with Clindesse (clindamycin phosphate) and in 32 of 85 patients (38%) treated with placebo. (rxlist.com)
- Adverse reactions occurring in ≥ 1% of patients receiving Clindesse (clindamycin phosphate) in the three clinical studies are shown in Table 1. (rxlist.com)
- 5 One small RCT with 49 patients compared a topical antibiotic with a topical antibiotic plus an oral antibiotic and failed to show a benefit with dual therapy. (cfp.ca)
- 5 Regarding which topical antibiotic to use, mupirocin and fusidic acid had similar efficacy based on 4 RCTs with 440 patients. (cfp.ca)
- This is especially important in many hospital settings where patients are not only exposed to various types and degrees of perturbations, such as antibiotics, diet changes, and chemotherapy, but they are also exposed to C. difficile spores from their environment ( 5 ). (asm.org)
- That s because lots of patients demand an antibiotic, convinced it s the only thing that will help them feel better. (care2.com)
- IV antibiotics are used to treat severe MRSA in patients who have failed to respond to other drugs. (ahefv.com)
- Unfortunately, not all patients with MRSA manage to cure a dangerous infectious disease after the first course of antibiotic therapy. (ahefv.com)
- Therefore, many patients have to use cheap oral antibiotics for MRSA treatment. (ahefv.com)
- However, patients should be reminded that use of this antibiotic may result to vomiting, abdominal pain, diarrhea and itching. (allhealthsite.com)
- Fifty patients (38.8%) had antibiotics determined by MCBT. (hindawi.com)
- Patients given antibiotics based on MCBT had significantly lower rates of septicaemia and lower rates of empyema. (hindawi.com)
- The conventional manner of managing patients who are colonised with these microorganisms is to empirically treat them with combinations of antibiotics in the peritransplant period. (hindawi.com)
- The same result is expected by the use and misuse of antibiotics used in the clinical veterinary practice. (frontiersin.org)
- Similar to the remark regarding the treatment for chorioamnionitis, the GDG suggested that antibiotic treatment should continue for at least 24-48 hours after complete resolution of clinical signs and symptoms (e.g. fever, uterine tenderness, purulent lochia, leucocytosis). (who.int)
- Clindamycin has been well established as antistaphylococcal therapy, but very few clinical data are available about its use in combination with rifampin for PJI. (biomedcentral.com)
- When an organism expressing iMLS B resistance is tested according to Clinical and Laboratory Standards Institute (CLSI) methods with a 15-μg erythromycin disk placed close to a 2-μg clindamycin disk, the zone of inhibition around the clindamycin disk is flattened to form a "D" shape (positive D-test), whereas in the MS phenotype, the clindamycin zone remains circular ( 7 ). (asm.org)
- In children who have features suggesting a bacterial etiology (eg, an infiltrate on chest radiograph and/or positive findings at sputum Gram stain), the administration of antibiotics may be good clinical practice. (medscape.com)
- Clinical practice guideline for the diagnosis and management of group a streptococcal pharyngitis: 2012 update by the infectious diseases society of america. (medscape.com)
- Kaplan EL, Chhatwal GS, Rohde M. Reduced ability of penicillin to eradicate ingested group A streptococci from epithelial cells: clinical and pathogenetic implications. (medscape.com)
- Addition of clindamycin (CLI) is recommended, although clinical evidence is lacking. (uzh.ch)
- the API system (bioMerieux Vitek), and the ATB Expression system (bioMerieux Vitek) are commonly used for microbial identification of beta-hemolytic streptococci in the clinical laboratory, none of these systems contains all four group G beta-hemolytic streptococci in the database. (asm.org)
- Clindesse (clindamycin phosphate) was studied in three clinical studies: placebo-controlled (n=85), active-controlled (n=263), and single-arm (n=20). (rxlist.com)
- Natural products serve as chemical blueprints for most antibiotics in clinical use. (nature.com)
- The evolutionary process by which these molecules arise is inherently accompanied by the co-evolution of resistance mechanisms that shorten the clinical lifetime of any given class of antibiotics 1 . (nature.com)
- Here, we report the effects of widely used antibiotics (clindamycin, ciprofloxacin, amoxicillin, and minocycline) with different modes of action on the ecology of both the gut and the oral microbiomes in 66 healthy adults from the United Kingdom and Sweden in a two-center randomized placebo-controlled clinical trial. (asm.org)
- This is the method used by many clinical laboratories from Group A Streptococci (GABHS) in many clinical laboratories. (antimicrobe.org)
- The purpose of this review is to summarize the currently accepted taxonomic classification of this group of organisms, examine the state of the art for identification of the VGS, and then focus on the pediatric clinical manifestations associated with the VGS. (pubmedcentralcanada.ca)
- These cases are predominantly normoandrogenic and have some clinical differences when compared with the most common group, the adolescent. (clinicaltrials.gov)
- [ 20 ] Many centers continue with intravenous antibiotics at least 48 hours after the patient is afebrile and the chest drain is removed. (medscape.com)
- This rationale does not preclude the clinician from giving an initial intravenous (IV) dose of antibiotics in the emergency department and then sending the patient home on oral agents, if the patient's condition warrants this action. (medscape.com)
- By the end of short-term intravenous infusion, peak serum concentrations of active clindamycin are reached. (nih.gov)
- Clindamycin Injection, USP for intramuscular and intravenous use, contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. (nih.gov)
- The patient was treated with intravenous ceftriaxone and clindamycin for 7 days. (contemporarypediatrics.com)
- He was discharged home, where intravenous clindamycin therapy was to be continued for 4 weeks. (contemporarypediatrics.com)
- The key management points are prompt administration of appropriate antibiotics, intravenous fluid replacement and source control. (renalandurologynews.com)
- Strains from 15 species were found resistant or multiresistant against 15 antimicrobial agents, representing all categories of antibiotics. (frontiersin.org)
- We also evaluated antimicrobial drug resistance and found that ST-459 strains were resistant to clindamycin and erythromycin, whereas strains of other STs were, for the most part, susceptible to these antimicrobial drugs. (cdc.gov)
- Lancefield groups A, B, C, and G streptococci are the major groups of beta-hemolytic streptococci that cause bacteremia. (asm.org)
- The major reservoir for group A and B streptococci is humans, whereas most group C beta-hemolytic streptococcal bacteremias in Hong Kong are of animal origin ( 28 ). (asm.org)
- In one study, group G streptococci were shown to be the most common cause of beta-hemolytic streptococcal bacteremia ( 16 ). (asm.org)
- Erysipelas, similar to cellulitis, may result from introduction of group A beta-hemolytic streptococci through breaks in the skin or in nearby sites. (neurologyadvisor.com)
- Perianal streptococcal dermatitis is a bright red, sharply demarcated rash that is caused by group A beta-hemolytic streptococci. (aafp.org)
- Perianal streptococcal dermatitis is caused by group A beta-hemolytic streptococci and occurs mainly in children between six months and 10 years of age. (aafp.org)
- 4 Notable changes in the 2010 revision addressed the use of IAP for women in preterm labor and those with preterm prelabor rupture of membranes (PROM), the choice of specific antibiotics for IAP, and the use of nucleic acid amplification tests (NAATs) to identify maternal GBS colonization. (aappublications.org)
- The aim of this study was to describe the GBS colonization rate, serotype distribution and antibiotic sensitivity profile in a rural population in South East Asia. (biomedcentral.com)
- It was previously shown that C57BL/6 mice treated with cefoperazone ( 3 , 7 ), tigecycline ( 8 ), clindamycin ( 9 ), or clindamycin in combination with a five-antibiotic cocktail ( 2 ) had decreased colonization resistance. (asm.org)
- Following a 7 day course of antibiotics, obtain a test of cure and record GBS colonization in the medical record because this woman requires IAP. (oncologynurseadvisor.com)
- Increased compliance in the use of topical sunscreens is obtained by combining a topical sunscreen agent in a formulation containing an antibacterial medication such as azelaic acid or an antibiotic. (google.es)
- Here we report the design, synthesis, and antibacterial evaluation of group A streptogramin antibiotics with extensive structural variability. (nature.com)
- how much does clindamycin cream cost vaginal cream is used to treat bacterial vaginosis. (alpine-club.org.uk)
- Clindesse (clindamycin phosphate) does not comply with the pH test of the USP monograph for clindamycin phosphate vaginal cream. (rxlist.com)
- Clindesse (clindamycin phosphate) Vaginal Cream, 2% , is available in cartons containing one single-dose, pre-filled disposable applicator ( NDC 64011-124-08). (rxlist.com)
- Each applicatorful of 5 grams of vaginal cream contains approximately 100 mg of clindamycin phosphate. (bioportfolio.com)
- Following a once a day intravaginal dose of 100 mg of clindamycin phosphate vaginal cream 2%, administered to 6 healthy female volunteers for 7 days, approximately 5% (range 0.6% to 11%) of the administered dose was absorbed systemically. (bioportfolio.com)
- Clindamycin phosphate vaginal cream 2%, can be used to treat non-pregnant women and pregnant women during the second and third trimester. (bioportfolio.com)
- Maternal management is addressed in ACOG Committee Opinion No. 782, "Prevention of Group B Streptococcal Early-Onset Disease in Newborns. (aappublications.org)
- There was an increased risk of caesarean section and duration of maternal stay in hospital with the use of antibiotics probably due to more hypertension and pre-eclampsia in the mothers of this group. (who.int)
- However, due to increasing problems with bacterial resistance and the risk of maternal anaphylaxis with antibiotic use, it is important to assess the evidence addressing risks and benefits in order to ensure judicious use of antibiotics. (who.int)
- To assess the effects of antibiotics administered prophylactically to women with PROM at 36 weeks' gestation or beyond, on maternal, fetal and neonatal outcomes. (who.int)
- Caesarean section was increased with the use of antibiotics (RR 1.33, 95% CI 1.09 to 1.61) as was duration of maternal stay in hospital (mean difference (MD) 0.06 days, 95% CI 0.01 to 0.11), largely owing to one study of 1640 women where repeat caesarean section, increased baseline hypertension and pre-eclampsia were evident in the antibiotic group, despite random allocation and allocation concealment. (who.int)
- which were erythromycin nonsusceptible but clindamycin susceptible were tested using the D-test performed at both 15-mm and 22-mm disk separations and compared with genotyping as the "gold standard. (asm.org)
- isolate as clindamycin susceptible. (asm.org)
- Is the isolate susceptible to clindamycin and erythromycin? (cdc.gov)
- However, some Group C Streptococci (GCS) are susceptible to bacitracin and may result in misidentification if Lancefield serologic typing is not performed. (antimicrobe.org)
- In the present study, we evaluated the efficacy and safety of a clindamycin-rifampin combination therapy regimen for the management of PJI caused by Staphylococcus species. (biomedcentral.com)
- The mean injury severity score was 22.6 and 21.2 in the single and double antibiotic regimen, respectively. (biomedsearch.com)
- in cases where antibiotics are deemed necessary, it is most appropriate that the orthopedic surgeon recommend the appropriate antibiotic regimen and, when reasonable, write the prescription. (ada.org)
- The novel therapy regimen adds a topical fixed-dose combination of a retinoid and an anti-bacterial agent, such as BPO, to a course of oral antibiotic therapy. (google.com)
- Where can i buy clindamycin phosphate topical lotion was given as two 150-mg tablets three times daily. (alpine-club.org.uk)
- Can topical antibiotics be used to treat impetigo? (cfp.ca)
- 5 There was also no evidence to support the combined use of a topical and an oral antibiotic for impetigo. (cfp.ca)
- In addition to being as effective as oral antibiotics, topical antibiotics have less systemic absorption and therefore less risk of adverse events. (cfp.ca)
- Influence of Disk Separation Distance on Accuracy of the Disk Approximation Test for Detection of Inducible Clindamycin Resistance in Staphylococcus spp. (asm.org)
- We undertook this study to assess the accuracy of the clindamycin-erythromycin disk approximation test (D-test) for detection of inducible clindamycin resistance in Staphylococcus spp. (asm.org)
- It is thus recommended by most experts that clindamycin therapy be avoided for Staphylococcus sp. (asm.org)
- Before starting antibiotic therapy, it is necessary to find out what tissues and organs are already infected with Staphylococcus aureus. (ahefv.com)
- Staph aureus (rarely MRSA or PVL), streptococci like group A and coliforms. (brainscape.com)
- Johnson, C. C. & Tunkel, A. R. (2000) Viridans streptococci and groups C and G streptococci. (springer.com)
- Lancefield, R. C. (1933) A serological differentiation of human and other groups of hemolytic streptococci. (springer.com)
- Stollerman, G. H. (1993) Variation in group A streptococci and the prevalence of rheumatic fever: a half-century vigil. (springer.com)
- Lancefield, R. C. (1962) Current knowledge of type-specific M antigens of group A streptococci. (springer.com)
- Cellulitis without an associated purulent lesion should be treated with antibiotics directed at CA-MRSA, MSSA, and group A b-hemolytic streptococci. (clinicaladvisor.com)
- Group B ( S. agalactiae ), Group C and G streptococci, and viridans group streptococci (VGS) are known to colonize human respiratory, gastrointestinal, and genitourinary tracts. (antimicrobe.org)
- Traditionally, streptococci are classified by the use of Lancefield group antigens and by hemolysis on blood agar. (antimicrobe.org)
- Large colony group C streptococci are usually resistant to bacitracin. (antimicrobe.org)
- The viridans group streptococci (VGS) are a heterogeneous group of organisms that can be human commensals, colonizing the gastrointestinal and genitourinary tracts in addition to the oral mucosa. (pubmedcentralcanada.ca)
- The viridans group streptococci (VGS) are a heterogeneous group of organisms that can be both commensal flora and pathogens in humans. (pubmedcentralcanada.ca)
- Acquired staphylococcal resistance to lincosamides such as clindamycin is largely mediated by ribosomal methylases encoded by one of several erm genes. (asm.org)
- As an inhibitor of protein synthesis, sildenafil citrate 100mg buy online clindamycin purchase binds to the 50s ribosomal subunit and is reported to inhibit peptidyltransferase and therfore affecting the process of peptide chain initiation. (alpine-club.org.uk)
- The antibiotic binds preferentially to the 50S ribosomal subunit and affects the process of peptide chain initiation. (bioportfolio.com)
- The fact that she also used natural product antibiotics to stabilize ribosomal structure added to my magnitude of admiration. (scienceblogs.com)
- Due to the spread of resistance, antibiotic exposure receives increasing attention. (asm.org)
- Feces and saliva were collected at baseline, immediately after exposure, and 1, 2, 4, and 12 months after administration of antibiotics or placebo. (asm.org)
- Additionally, exposure to different antibiotics enriched genes associated with antibiotic resistance. (asm.org)
- With respect to the study carried out to investigate the capability of ALS-4 to induce antibiotic resistance in S. aureus after prolonged exposure, USA300-LAC was cultured in 3 different conditions for 10 days. (newsmaker.com.au)
- 46% preferred to continue antibiotics until drain removal, while 52% preferred a specific postoperative day, most commonly day 5 or 7. (clinicaltrials.gov)
- In a hospitalized patient with complicated parapneumonic effusion, antibiotics are commonly administered intravenously while a thoracostomy tube is present and the patient is febrile. (medscape.com)
- Thereafter, oral antibiotics are commonly continued for 2-4 weeks. (medscape.com)
- This group has been poorly defined for many years because of the paucity of commonly queried substrates hydrolyzed by the group. (pubmedcentralcanada.ca)
- Clindamycin in 5% dextrose injection in bottles contains clindamycin phosphate equivalent to 300, 600 and 900 mg of clindamycin premixed with 5% dextrose as a sterile solution. (nih.gov)
- Each mL contains clindamycin phosphate equivalent to 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as preservative. (nih.gov)
- Clindesse is a semi-solid, white cream, which contains clindamycin phosphate, USP, at a concentration equivalent to 20 mg clindamycin base per gram. (rxlist.com)
- After four weeks, the reduction in the pruritus score was between 45 and 50 per cent in the CIM331 group compared to 20 per cent in the placebo group. (bad.org.uk)
- All randomised trials that compared outcomes for women and infants when antibiotics were administered prophylactically for prelabour rupture of the membranes at or near term, with outcomes for controls (placebo or no antibiotic). (who.int)
- Seven randomized controlled trials have evaluated the effect of various antibiotic treatments versus placebo on pregnancy outcomes among women with BV: Three studies enrolled only high-risk women (primarily history of prior preterm delivery), two reported results separately for women with and without a prior history of preterm delivery, and two enrolled average-risk women. (ispub.com)
- 55. The composition of claim 1 , wherein the composition comprises clindamycin, niacinamide, and azelaic acid. (freepatentsonline.com)
- 56. The composition of claim 1 , wherein the composition comprises clindamycin, zinc pyrithione, and azelaic acid. (freepatentsonline.com)
- 58. A composition comprising between 4% w/w and 20% w/w azelaic acid, between 0.01% w/w and 2% w/w zinc pyrithione, and between 0.5% w/w and 1.5% w/w clindamycin. (freepatentsonline.com)
- 60. A composition comprising between 0.02% w/w and 0.14% w/w tretinoin, between 4% w/w and 20% w/w azelaic acid, and between 0.5% w/w and 1.5% w/w clindamycin. (freepatentsonline.com)
- 62. A composition comprising between 0.1% w/w and 25% w/w azelaic acid, between 2% w/w and 6% w/w niacinamide, and between about 0.5% w/w and 1.5% w/w clindamycin. (freepatentsonline.com)
- The rate of inducible clindamycin resistance was 96.3% for S. aureus and 33.8% for CoNS spp. (asm.org)
- This novel mechanism is significantly different from the bactericidal approach found in currently marketed antibiotics used to treat S. aureus, which are experiencing increasing drug resistance issues2. (newsmaker.com.au)
- Additionally, according to the CDC guideline report, in vitro resistance to both clindamycin and erythromycin has been increasing, with reports published from 2006 to 2009 finding GBS resistance ranging from 25% to 32% for erythromycin and from 13% to 20% for clindamycin ( 6 ). (asm.org)
- In vitro studies in human liver and intestinal microsomes indicated that clindamycin is predominantly metabolized by Cytochrome P450 3A4 (CYP3A4), with minor contribution from CYP3A5, to form clindamycin sulfoxide and a minor metabolite, N-desmethylclindamycin. (nih.gov)
- Clindamycin injection may contain an ingredient that can cause serious side effects or death in very young or premature babies. (alpine-club.org.uk)
- This leaflet answers some common questions about clindamycin injection. (nps.org.au)
- Your doctor has weighed the risks of you taking clindamycin injection against the benefits this medicine is expected to have for you. (nps.org.au)
- Your doctor may have prescribed CLINDAMYCIN MYLAN injection for another reason. (nps.org.au)