AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
GranulomaGranuloma, Foreign-BodyGranuloma, PyogenicEosinophilic GranulomaGranuloma, Respiratory TractGranuloma AnnulareGranuloma, Giant CellGranuloma InguinalePeriapical GranulomaGranuloma, LaryngealLiver Diseases, ParasiticSchistosomiasis mansoniTuberculomaSchistosoma mansoniSarcoidosisMycobacterium marinumSarcoidosis, PulmonaryLung Diseases, ParasiticSchistosomiasisGranuloma, Plasma CellPlasma Cell Granuloma, PulmonaryEpithelioid CellsGranuloma, Lethal MidlineGingival DiseasesLung DiseasesMycobacterium bovisOvumForeign-Body ReactionMycobacterium tuberculosisTuberculosis, HepaticMycobacterium InfectionsLungAntigens, HelminthCord FactorsMice, Inbred CBACalymmatobacteriumSkin DiseasesTuberculosisSchistosomaFacial DermatosesLiver DiseasesNeurocysticercosisMacrophagesTuberculosis, PulmonaryMycobacterium aviumSchistosomiasis japonicaPetrous BoneTuberculosis, Lymph NodeMycobacterium Infections, NontuberculousMice, Inbred C57BLBiopsyLiverSchistosoma japonicumTuberculosis, CutaneousSplenic DiseasesInterferon-gammaLip Diseases
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.Granuloma, Foreign-Body: Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.Granuloma, Pyogenic: A disorder of the skin, the oral mucosa, and the gingiva, that usually presents as a solitary polypoid capillary hemangioma often resulting from trauma. It is manifested as an inflammatory response with similar characteristics to those of a granuloma.Eosinophilic Granuloma: The most benign and common form of Langerhans-cell histiocytosis which involves localized nodular lesions predominantly of the bones but also of the gastric mucosa, small intestine, lungs, or skin, with infiltration by EOSINOPHILS.Granuloma, Respiratory Tract: Granulomatous disorders affecting one or more sites in the respiratory tract.Granuloma Annulare: Benign granulomatous disease of unknown etiology characterized by a ring of localized or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures.Granuloma, Giant Cell: A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.Granuloma Inguinale: Anogenital ulcers caused by Calymmatobacterium granulomatis as distinguished from lymphogranuloma inguinale (see LYMPHOGRANULOMA VENEREUM) caused by CHLAMYDIA TRACHOMATIS. Diagnosis is made by demonstration of typical intracellular Donovan bodies in crushed-tissue smears.Periapical Granuloma: Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.Granuloma, Laryngeal: A tumor-like nodule or mass of inflammatory granulation tissue projecting into the lumen of the LARYNX.Liver Diseases, Parasitic: Liver diseases caused by infections with PARASITES, such as tapeworms (CESTODA) and flukes (TREMATODA).Schistosomiasis mansoni: Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.Tuberculoma: A tumor-like mass resulting from the enlargement of a tuberculous lesion.Schistosoma mansoni: A species of trematode blood flukes of the family Schistosomatidae. It is common in the Nile delta. The intermediate host is the planorbid snail. This parasite causes schistosomiasis mansoni and intestinal bilharziasis.Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.Mycobacterium marinum: A moderate-growing, photochromogenic species found in aquariums, diseased fish, and swimming pools. It is the cause of cutaneous lesions and granulomas (swimming pool granuloma) in humans. (Dorland, 28th ed)Sarcoidosis, Pulmonary: Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)Lung Diseases, Parasitic: Infections of the lungs with parasites, most commonly by parasitic worms (HELMINTHS).Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.Granuloma, Plasma Cell: A slow-growing benign pseudotumor in which plasma cells greatly outnumber the inflammatory cells.Plasma Cell Granuloma, Pulmonary: A tumor-like inflammatory lesion of the lung that is composed of PLASMA CELLS and fibrous tissue. It is also known as an inflammatory pseudotumor, often with calcification and measuring between 2 and 5 cm in diameter.Epithelioid Cells: Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages that have differentiated as a result of prolonged antigenic stimulation. Further differentiation or fusion of epithelioid cells is thought to produce multinucleated giant cells (GIANT CELLS).Granuloma, Lethal Midline: A condition that is characterized by inflammation, ulceration, and perforation of the nose and the PALATE with progressive destruction of midline facial structures. This syndrome can be manifested in several diseases including the nasal type of EXTRANODAL NK-T-CELL LYMPHOMA and GRANULOMATOSIS WITH POLYANGIITIS.Gingival DiseasesLung Diseases: Pathological processes involving any part of the LUNG.Mycobacterium bovis: The bovine variety of the tubercle bacillus. It is called also Mycobacterium tuberculosis var. bovis.Ovum: A mature haploid female germ cell extruded from the OVARY at OVULATION.Foreign-Body Reaction: Chronic inflammation and granuloma formation around irritating foreign bodies.Mycobacterium tuberculosis: A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.Tuberculosis, Hepatic: Infection of the LIVER with species of MYCOBACTERIUM, most often MYCOBACTERIUM TUBERCULOSIS. It is characterized by localized small tuberculous miliary lesions or tumor-like mass (TUBERCULOMA), and abnormalities in liver function tests.Mycobacterium Infections: Infections with bacteria of the genus MYCOBACTERIUM.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Antigens, Helminth: Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.Cord Factors: Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals.Mice, Inbred CBACalymmatobacterium: A genus of bacteria causing GRANULOMA INGUINALE and other granulomatous lesions.Skin DiseasesTuberculosis: Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM.Schistosoma: A genus of trematode flukes belonging to the family Schistosomatidae. There are over a dozen species. These parasites are found in man and other mammals. Snails are the intermediate hosts.Facial DermatosesLiver Diseases: Pathological processes of the LIVER.Neurocysticercosis: Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)Macrophages: The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)Tuberculosis, Pulmonary: MYCOBACTERIUM infections of the lung.Mycobacterium avium: A bacterium causing tuberculosis in domestic fowl and other birds. In pigs, it may cause localized and sometimes disseminated disease. The organism occurs occasionally in sheep and cattle. It should be distinguished from the M. avium complex, which infects primarily humans.Schistosomiasis japonica: Schistosomiasis caused by Schistosoma japonicum. It is endemic in the Far East and affects the bowel, liver, and spleen.Petrous Bone: The dense rock-like part of temporal bone that contains the INNER EAR. Petrous bone is located at the base of the skull. Sometimes it is combined with the MASTOID PROCESS and called petromastoid part of temporal bone.Tuberculosis, Lymph Node: Infection of the lymph nodes by tuberculosis. Tuberculous infection of the cervical lymph nodes is scrofula.Mycobacterium Infections, Nontuberculous: Infections with nontuberculous mycobacteria (atypical mycobacteria): M. kansasii, M. marinum, M. scrofulaceum, M. flavescens, M. gordonae, M. obuense, M. gilvum, M. duvali, M. szulgai, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. xenopi (littorale), M. ulcerans, M. buruli, M. terrae, M. fortuitum (minetti, giae), M. chelonae.Mice, Inbred C57BLBiopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Schistosoma japonicum: A species of trematode blood flukes belonging to the family Schistosomatidae whose distribution is confined to areas of the Far East. The intermediate host is a snail. It occurs in man and other mammals.Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.Splenic DiseasesInterferon-gamma: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.Lip Diseases

Systemic infection with Alaria americana (Trematoda). (1/1842)

Alaria americana is a trematode, the adult of which is found in mammalian carnivores. The first case of disseminated human infection by the mesocercarial stage of this worm occurred in a 24-year-old man. The infection possibly was acquired by the eating of inadequately cooked frogs, which are intermediate hosts of the worm. The diagnosis was made during life by lung biopsy and confirmed at autopsy. The mesocercariae were present in the stomach wall, lymph nodes, liver, myocardium, pancreas and surrounding adipose tissue, spleen, kidney, lungs, brain and spinal cord. There was no host reaction to the parasites. Granulomas were present in the stomach wall, lymph nodes and liver, but the worms were not identified in them. Hypersensitivity vasculitis and a bleeding diathesis due to disseminated intravascular coagulation and a circulating anticoagulant caused his death 8 days after the onset of his illness.  (+info)

Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni. (2/1842)

In murine schistosomiasis mansoni, CD4(+) Th1 and Th2 cells participate in the ovum-induced granulomatous inflammation. Previous studies showed that the interleukin-12 (IL-12)-induced Th1 response strongly suppressed the Th2-cell-mediated pulmonary granuloma development in naive or primed mice. However, liver granulomas were only moderately suppressed in egg-vaccinated, recombinant IL-12 (rIL-12)-treated infected mice. The present study shows that repeated rIL-12 injections given during early granuloma development at 5 to 7 weeks after infection prolonged the Th1 phase and resulted in gamma interferon-mediated suppression of liver granulomas. The timing is crucial: if given at 6 to 8 weeks, during the Th2-dominated phase of florid granuloma growth, the treatment is ineffective. Daily injections of rIL-12 given between 5 and 7.5 weeks during the period of granuloma growth achieved a somewhat-stronger diminution in granuloma growth with less deposition of collagen but caused 60% mortality and liver pathology. In contrast, combined treatment with rIL-12 and anti-IL-4-anti-IL-10 monoclonal antibody (MAb) injections given during the Th2 phase strongly inhibited liver granuloma growth without mortality. The diminished inflammatory response was accompanied by less deposition of collagen in the liver. Moreover, neutralization of endogenous IL-12 by anti-IL-12 MAbs effectively decreased the early Th1 phase (between 5 and 6 weeks after infection) but not the developing Th2 phase (5 to 7 weeks) of granuloma development. These studies indicate that the granulomatous response in infected mice can be manipulated by utilizing the Th1-Th2-subset antagonism with potential salutary results in the amelioration of fibrous pathology.  (+info)

N,N'-Diacetyl-L-cystine-the disulfide dimer of N-acetylcysteine-is a potent modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. (3/1842)

Oral N-acetyl-L-cysteine (NAC) is used clinically for treatment of chronic obstructive pulmonary disease. NAC is easily oxidized to its disulfide. We show here that N,N'-diacetyl-L-cystine (DiNAC) is a potent modulator of contact sensitivity (CS)/delayed type hypersensitivity (DTH) reactions in rodents. Oral treatment of BALB/c mice with 0.003 to 30 micromol/kg DiNAC leads to enhancement of a CS reaction to oxazolone; DiNAC is 100 to 1000 times more potent than NAC in this respect, indicating that it does not act as a prodrug of NAC. Structure-activity studies suggest that a stereochemically-defined disulfide element is needed for activity. The DiNAC-induced enhancement of the CS reaction is counteracted by simultaneous NAC-treatment; in contrast, the CS reaction is even more enhanced in animals treated with DiNAC together with the glutathione-depleting agent buthionine sulfoximine. These data suggest that DiNAC acts via redox processes. Immunohistochemically, ear specimens from oxazolone-sensitized and -challenged BALB/c mice treated with DiNAC display increased numbers of CD8(+) cells. DiNAC treatment augments the CS reaction also when fluorescein isothiocyanate is used as a sensitizer in BALB/c mice; this is a purported TH2 type of response. However, when dinitrofluorobenzene is used as a sensitizer, inducing a purported TH1 type of response, DiNAC treatment reduces the reaction. Treatment with DiNAC also reduces a DTH footpad-swelling reaction to methylated BSA. Collectively, these data indicate that DiNAC in vivo acts as a potent and effective immunomodulator that can either enhance or reduce the CS or DTH response depending on the experimental conditions.  (+info)

The requirement of an adherent cell substratum for the growth of developing plasmacytoma cells in vivo. (4/1842)

The intraperitoneal injection of pristane (2,6,10,14-tetramethylpentadecane) produces an environment conductive to primary plasmacytoma growth in as few as 3 days. After pristane injection, the total free peritoneal cell population increases from a normal value of 1.55 X 10(6) to 5.28 X 10(6) and remains at this elevated level for at least 50 days. The adherent peritoneal cell population, composed of both mononuclear cells and polymorphonuclear leukocytes, is the primary source of this increase. In the pristane-conditioned peritoneum, these cells rapidly form a chronic granuloma on the peritoneal connective tissues. Daily subcutaneous treatment of mice with 0.5 mg of hydrocortisone beginning simultaneously with pristane injection prevents the increase in the peritoneal cell population, granuloma formation, d the production of a conditoned environment. In mice treated with hydrocortisone beginning 3 days after pristane injection, however, neither the peritoneal cell increase nor the production of a conditioned environment is prevented. The intraperitoneal injection of thioglycolate medium at 4-day intervals produces an elevation of the free adherent peritoneal cell population similar to pristane, but does not produce a granuloma or a conditioned environment. The intraperitoneal transfer of thioglycolate-induced adherent peritonel cells to mice treated with pristane and hydrocortisone simultaneously restores the production of a conditioned environment. These findings indicate that the adherent peritoneal cell population is responsible for the conditioning effect, and that the establishment of a resident population of these cells is necessary to produce conditioning.  (+info)

Experimental murine schistosomiasis in the absence of B7 costimulatory molecules: reversal of elicited T cell cytokine profile and partial inhibition of egg granuloma formation. (5/1842)

The granulomatous inflammation in infection with the helminth Schistosoma mansoni represents a cellular hypersensitivity reaction mediated by, and dependent upon, MHC class II-restricted CD4+ Th cells sensitized to parasite egg Ags. The current work examines the role and significance of the B7:CD28/CTLA-4 pathway in providing the costimulation necessary for the activation of these pathogenic T cells. In vitro T cell responses in B7-1-/- mice, 7-8 wk postinfection, were no different from wild-type controls, but the absence of B7-2 molecules resulted in a decrease in egg Ag-induced proliferation with increased IFN-gamma production. Both B7-1-/- and B7-2-/- mice exhibited intact granuloma formation. In contrast, CD4+ Th cells from B7-1/2 double-deficient mice displayed a dramatic loss of proliferative capacity upon stimulation with egg Ag. Most strikingly, these T cells secreted only IFN-gamma, but not IL-4 and IL-10, a pattern entirely opposite to that displayed by wild-type controls. Despite these major differences in T cell reactivity, B7-1/2-/- mice had only a limited reduction of granuloma size and fibrosis, without appreciable difference in cellular composition. These results show that substantial granuloma formation can occur under conditions of limited T cell expansion and restricted Th1-type cytokine production. They also support the notion that the combined effect of B7 signaling is not as critical for Th1 cell activation as it is for the development of the Th2 dominant environment characteristic of the evolving schistosome infection in H-2b mice.  (+info)

Role of macrophage scavenger receptors in hepatic granuloma formation in mice. (6/1842)

In mice homozygous for the gene mutation for type I and type II macrophage scavenger receptors (MSR-A), MSR-A-/-, the formation of hepatic granulomas caused by a single intravenous injection of heat-killed Corynebacterium parvum was delayed significantly for 10 days after injection, compared with granuloma formation in wild-type (MSR-A+/+) mice. In the early stage of granuloma formation, numbers of macrophages and their precursor cells were significantly reduced in MSR-A-/- mice compared with MSR-A+/+ mice. In contrast to MSR-A+/+ mice, no expression of monocyte chemoattractant protein-1, tumor necrosis factor-alpha, and interferon-gamma mRNA was observed in MSR-A-/- mice by 3 days after injection. Also in MSR-A-/- mice, uptake of C. parvum by Kupffer cells and monocyte-derived macrophages in the early stage of granuloma formation was lower and elimination of C. parvum from the liver was slower than in MSR-A+/+ mice. In the livers of MSR-A+/+ mice, macrophages and sinusoidal endothelial cells possessed MSR-A, but this was not seen in the livers of MSR-A-/- mice. In both MSR-A-/- and MSR-A+/+ mice, expression of other scavenger receptors was demonstrated. These data suggest that MSR-A deficiency impairs the uptake and elimination of C. parvum by macrophages and delays hepatic granuloma formation, particularly in the early stage.  (+info)

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs. (7/1842)

Chronic granulomatous disease (CGD) is a genetic disorder of NADPH oxidase in which phagocytes are defective in generating reactive oxidants. CGD patients suffer from recurrent infections and exuberant and persistent tissue granuloma formation. We hypothesized that abnormal granulomata in CGD may result from aberrant T-cell-mediated cytokine responses. To assess Th-1-type cytokine responses and granulomata, we challenged p47(phox-/-) and wild-type mice with avirulent (SmD) or virulent (SmT) variants of Mycobacterium avium 2-151. To assess Th-2-type cytokine responses and granulomata, we used Schistosoma mansoni eggs (SME). Mononuclear cells were harvested, and cytokine responses were determined by enzyme-linked immunosorbent assay or reverse transcriptase PCR. Following SmD or SmT challenge, splenocytes from p47(phox-/-) and wild-type mice generated similar polar Th-1 responses (increased levels of gamma interferon and basal levels of interleukin 4 [IL-4] and IL-5). By 8 weeks after SmT challenge, exuberant splenic granulomata developed in p47(phox-/-) and wild-type mice. After SME challenge, thoracic lymph node mononuclear cells from p47(phox-/-) and wild-type mice generated similar mixed Th-1 and Th-2 cytokine responses to SME antigen and concanavalin A. Peak lung granuloma sizes and rates of regression were similar in p47(phox-/-) and wild-type mice. These results suggest that exuberant granulomatous inflammation in CGD is probably not the result of skewing of T-cell responses toward the Th-1 or Th-2 pole. Appropriate regression of established tissue granulomata in p47(phox-/-) mice challenged with SME suggests that abnormal granuloma formation in CGD is stimulus dependent and is not an invariant feature of the disease.  (+info)

Sarcoidosis of the upper respiratory tract and its association with lupus pernio. (8/1842)

In a series of 34 patients with sarcoidosis affecting the upper respiratory tract and nose, 26 had lupus pernio (LP) and 17 had sarcoidosis of the upper respiratory tract (SURT). In nine patients these features coexisted. A patient presenting with SURT carried a 50% risk of developing LP although one feature could be present without the other. Both were disorders of women of the child-bearing years of life. SURT, like LP, was an indicator of chronic fibrotic sarcoidosis, developing insidiously and progressing indolently over the years. It was complicated by ulceration, septal perforation, and LP. Three patients had nasal septal perforations, in two instances following submucous resection. This operation is contraindicated in patients with active sarcoidosis, particularly when granulomas are found on nasal biopsy. The Kveim-Siltzbach skin test was positive in all patients with SURT, making it invaluable in the differential diagnosis of granuloma of the nasal cavity.  (+info)

Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule-1. | The Journal of...Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule-1. | The Journal of...
Recent studies have demonstrated a crucial role for TNF during inflammatory granuloma formation. In addition, TNF has been shown to up-regulate adhesion molecules that participate in cellular recruitment and lymphocyte activation. In the present study, we have examined the mechanism of TNF activation during Schistosoma mansoni egg granuloma formation and its relationship to the expression of ICAM-1. Our initial studies showed that high affinity human soluble TNFR coupled to the Fc portion of an Ig (sTNFR:Fc construct) could effectively diminish granuloma formation and lymphocyte activation in vivo. We have also assessed the increased expression of ICAM-1, its contribution to granuloma development, and its relationship with TNF during lesion formation. Increased steady state ICAM-1 mRNA expression was observed in primary egg granulomas when compared with normal lung and foreign body (Sephadex bead) granulomas, which suggests a role for ICAM-1 in Ag-induced lesion formation. Subsequent studies ...
Granuloma - WikipediaGranuloma - Wikipedia
In pathology, a granuloma is an organized collection of macrophages.[1][5]. In medical practice, doctors occasionally use the term "granuloma" in its more literal meaning: "a small nodule". Since a small nodule can represent anything from a harmless nevus to a malignant tumor, this usage of the term is not very specific. Examples of this use of the term granuloma are the lesions known as vocal cord granuloma (known as contact granuloma), pyogenic granuloma and intubation granuloma, all of which are examples of granulation tissue, not granulomas. "Pulmonary hyalinizing granuloma" is a lesion characterized by keloid-like fibrosis in the lung, and is not granulomatous. Similarly, radiologists often use the term granuloma when they see a calcified nodule on X-ray or CT scan of the chest. They make this assumption since granulomas usually contain calcium, although the cells that form a granuloma are too tiny to be seen by a radiologist. The most accurate use of the term "granuloma" requires a ...
Granuloma - WikipediaGranuloma - Wikipedia
In pathology, a granuloma is an organized collection of macrophages.[1][5]. In medical practice, doctors occasionally use the term "granuloma" in its more literal meaning: "a small nodule". Since a small nodule can represent anything from a harmless nevus to a malignant tumor, this usage of the term is not very specific. Examples of this use of the term granuloma are the lesions known as vocal cord granuloma (known as contact granuloma), pyogenic granuloma and intubation granuloma, all of which are examples of granulation tissue, not granulomas. "Pulmonary hyalinizing granuloma" is a lesion characterized by keloid-like fibrosis in the lung, and is not granulomatous. Similarly, radiologists often use the term granuloma when they see a calcified nodule on X-ray or CT scan of the chest. They make this assumption since granulomas usually contain calcium, although the cells that form a granuloma are too tiny to be seen by a radiologist. The most accurate use of the term "granuloma" requires a ...
What is a Lung Granuloma?What is a Lung Granuloma?
Granulomas are nodules caused by inflammation. The inflammation may be the result of infectious or noninfectious causes. Granulomas in the lung typically do not produce any symptoms, but may be detected when a chest x-ray is done for another reason.. Infectious causes of lung granulomas. Infections are the most common cause of lung granulomas, and these infections often involve mycobacteria or fungi.[1] Mycobacteria include tuberculosis as well as organisms that are referred to jointly as nontuberculous mycobacteria (NMT). NMT are found in water and soil.. Fungi that can lead to lung granulomas include Histoplasma, Coccidioides, and Cryptococcus. These fungi are found in soil (and sometimes in bird or bat droppings), and lung infection occurs when the spores are inhaled. [2] [3] [4]. Several other lung infections can also lead to lung granulomas, but are less common.. Non-infectious causes of lung granulomas. Sarcoidosis is the most common noninfectious cause of lung granulomas in the United ...
Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of...Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of...
Large populations of macrophages are a prominent feature of tuberculous granulomas, yet there are many unanswered questions surrounding the spatial organization of macrophage subsets in granulomas and whether macrophages have microenvironment-specific homeostatic or bactericidal functions. Much of what we know about granuloma macrophages comes from animal models that may not represent the spectrum of pathology seen in humans or has been derived from cells removed from the context of the granuloma. To address these questions, we used immunohistochemistry to clarify the interplay of microenvironment and macrophage biology by identifying macrophage subsets and arginase and NOS expression in granulomas from cynomolgus macaques, a nonhuman primate that recapitulates human TB (4). We found that granulomas have macrophage subsets that are stratified into pro- and anti-inflammatory regions with the implication that this organization may limit immunopathogenic antimicrobial activity to bacteria-rich ...
lung granuloma - Symptoms, Treatments and Resources for lung granulomalung granuloma - Symptoms, Treatments and Resources for lung granuloma
lung granuloma - MedHelps lung granuloma Center for Information, Symptoms, Resources, Treatments and Tools for lung granuloma. Find lung granuloma information, treatments for lung granuloma and lung granuloma symptoms.
GRANULOMA SARCOIDEO PDFGRANULOMA SARCOIDEO PDF
Br J Dermatol. Cutaneous granulomas associated with primary immunodeficiency disorders. We report cutaneous granulomas in a child with ataxia telangiectasia AT and compare the clinical course with similar lesions in an adult with common variable immunodeficiency CVI. A 4-year-old female with AT developed cutaneous granulomas as erythematous plaques. The largest lesion appeared on her left cheek and continued to progress despite treatment with topical and intralesional steroids.. Disease control was obtained initially with oral antibiotics and low-dose oral steroids. On cessation of oral steroids, significant relapse of the facial granuloma occurred. Pulsed and then oral steroids were required to stop the disease process leaving significant scarring. The second case is of cutaneous granulomas in a year-old man, with CVI, who presented with an erythematous reticulate rash on the legs.. We consider it useful to report this patient here as disease control was obtained in a similar way with systemic ...
Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type...Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type...
During acute schistosomiasis worm ova released from adult S. japonicum elicit potent pro-inflammatory responses along with characteristic granuloma formation, which then causes substantial injuries to organs such as the liver and intestine where the eggs are trapped (Hirata et al., 2001). As a result, anti-inflammatory responses to limit excessive liver injury or intestinal hemorrhage are necessary to prevent host lethality (Herbert et al., 2008). In general, acute schistosomiasis is considered a Th1 disease (de Jesus et al., 2002), and a defect in developing a Th2 response during acute schistosomiasis is associated with high lethality in mice (Rani et al., 2012). Given that alternatively activated M2 macrophages possess a high capacity for secretion of Th2 cytokines, their role in limiting pro-inflammatory responses and granuloma formation during acute schistosomiasis has been highly appreciated.. Previous studies have suggested that the trafficking of monocytes and macrophages from peripheral ...
Unscramble granulomas | Words unscrambled from letters granulomas | Scrabble Word granulomas | Words Made with the Letters...Unscramble granulomas | Words unscrambled from letters granulomas | Scrabble Word granulomas | Words Made with the Letters...
Unscramble granulomas, Unscramble letters granulomas, Point value for granulomas, Word Decoder for granulomas, Word generator using the letters granulomas, Word Solver granulomas, Possible Scrabble words with granulomas, Anagram of granulomas
Unusual Delayed FDG-PET/CT Hypermetabolism Due to Charcoal-Induced GranulomaUnusual Delayed FDG-PET/CT Hypermetabolism Due to Charcoal-Induced Granuloma
Charcoal, also called black carbon, is used for preoperative localization of tumor (mainly for breast tumors) or needle track localization after biopsy (mainly sarcomas biopsy, due to a potential risk of tumor seeding along needle track with this type of tumor).. Foreign-body granulomas can lead to false-positive findings of FDG PET/CT due to strong FGD uptake. On unenhanced CT, granulomas can show variable configurations, as delimited oval or round shape, or amorphous and linear configuration. Charcoal-induced granulomas usually show a spontaneous high attenuation, due to the high density of carbon particles, and no remarkable enhancement after contrast injection. On US studies, charcoal granulomas are characterized as irregular-shaped lesions, most often with hyperechogenicity and posterior shadowing. On the contrary, tumor recurrences often appear hypoechoic.. As described by Jin Woo Choi, charcoal is known to be a safe and biologically inert material when injected subcutaneously and may ...
Frontiers | Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model | ImmunologyFrontiers | Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model | Immunology
Mycobacterium tuberculosis is the pathogenic bacterium that causes tuberculosis (TB), one of the most lethal infectious diseases in the world. The only vaccine against TB is minimally protective, and multi-drug resistant TB necessitates new therapeutics to treat infection. Developing new therapies requires a better understanding of the complex host immune response to infection, including dissecting the processes leading to formation of granulomas, the dense cellular lesions associated with TB. In this work we pair experimental and computational modeling studies to explore cytokine regulation in the context of TB. We use our next-generation hybrid multi-scale model of granuloma formation (GranSim) to capture molecular, cellular, and tissue scale dynamics of granuloma formation. We identify TGF-β1 as a major inhibitor of cytotoxic T-cell effector function in granulomas. Deletion of TGF-β1 from the system results in improved bacterial clearance and lesion sterilization. We also identify a novel
Faculty Collaboration Database - Ideal Particle Sizes for Inhaled Steroids Targeting Vocal Granulomas: Preliminary Study Using...Faculty Collaboration Database - Ideal Particle Sizes for Inhaled Steroids Targeting Vocal Granulomas: Preliminary Study Using...
Objectives Vocal fold granulomas are benign lesions of the larynx commonly caused by gastroesophageal reflux, intubation, and phonotrauma. Current medical therapy includes inhaled corticosteroids to target inflammation that leads to granuloma formation. Particle sizes of commonly prescribed inhalers range over 1 to 4 µm. The study objective was to use computational fluid dynamics to investigate deposition patterns over a range of particle sizes of inhaled corticosteroids targeting the larynx and vocal fold granulomas. Study Design Retrospective, case-specific computational study. Setting Tertiary academic center. Subjects/Methods A 3-dimensional anatomically realistic computational model of a normal adult airway from mouth to trachea was constructed from 3 computed tomography scans. Virtual granulomas of varying sizes and positions along the vocal fold were incorporated into the base model. Assuming steady-state, inspiratory, turbulent airflow at 30 L/min, computational fluid dynamics was used ...
Letters to the Editor: Noninvasive Treatments for Umbilical Granulomas - American Family PhysicianLetters to the Editor: Noninvasive Treatments for Umbilical Granulomas - American Family Physician
IN REPLY: Thanks to Dr. Wooltorton for a nice and optimistic overview of noninvasive treatments for umbilical granulomas. I would add a resource1 to his armamentarium that praises the curative effect of common salt on umbilical granuloma. This article1 states that the high concentration of sodium ion in the area draws water out of the cells and results in shrinkage and necrosis of the wet granulomatous tissue.. However, contrary to Dr. Wooltortons impression, we did not ignore the easily reversed root causes of these lesions; we mentioned them in the first two sentences of the abstract and the first part of the discussion of the article.2 Dr. Wooltorton also implies that our technique is only pertinent for small umbilical granulomas such as in the case we presented in our article.2 In reality, it is effective for large pedunculated granulomas and avoids a prolonged and usually unsuccessful trial of conservative treatment. In our experience of treating hundreds of umbilical granulomas in ...
Contact Granulomas Treatment & Management: Medical Therapy, Surgical Therapy, Preoperative DetailsContact Granulomas Treatment & Management: Medical Therapy, Surgical Therapy, Preoperative Details
Contact granulomas are benign lesions usually located on the posterior third of the vocal fold, which corresponds to the vocal process of the arytenoid cartilage. Contact granulomas may occur unilaterally or bilaterally.
Case 18--Image 3Case 18--Image 3
Image 4. Table of Contents Answer: This is a non-necrotizing granuloma that is composed of epithelioid cells, multinucleated giant cells, and lymphocytes. The asterisk marks a Langhans giant cell with peripherally-oriented nuclei. The epithelioid cells are activated macrophages that have a secretory function rather than a phagocytic one. Metabolic products include calcium salts that can crystallize to form birefringent crystals, which must not be mistaken for foreign bodies.. Return. Answer: The respiratory problems that developed while the patient was keeping pets, the patchy ground-glass opacities and micronodules on HRCT, the evidence of air trapping on expiratory CT, the bronchiolar and patchy, alveolar lymphoid infiltrates and non-necrotizing granulomas are consistent with the diagnosis of hypersensitivity pneumonia. In this case no precipitating antibodies to common antigens, including pigeon antigens, were identified. After the animals were removed, her symptoms diminished without ...
Read-Only Case Details Reviewed: Sep 2008Read-Only Case Details Reviewed: Sep 2008
JPC SYSTEMIC PATHOLOGY. RESPIRATORY SYSTEM. August 2017. P-B10. Signalment ( #87-650): Rhesus monkey. HISTORY: This monkey was found dead in its cage.. HISTOPATHOLOGIC DESCRIPTION: SLIDE A: Lung: Up to 75% percent of the parenchyma is replaced by multifocal to coalescing granulomas composed of necrotic centers with occasional mineralization surrounded by numerous epithelioid macrophages, multinucleated giant cells (Langhans and foreign body type), and more peripherally by lymphocytes and plasma cells. Some granulomas are circumscribed by a thin fibrous connective tissue capsule. Multifocally, remaining alveolar septa are lined by hyperplastic type II pneumocytes. Alveolar spaces contain eosinophilic proteinaceous material (edema) admixed with numerous foamy alveolar macrophages, fewer lymphocytes, and scattered hemorrhage and fibrin. Multifocally, aggregates of lymphocytes and plasma cells surround blood vessels, which occasionally contain fibrin thrombi. Diffusely, the pleura is thickened to up ...
For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection - Dorhoi -...For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection - Dorhoi -...
Summary: Tuberculosis (TB) is a complex disease, and the success of the bacterium as an intracellular pathogen is the outcome of its close and longstanding coevolution with the mammalian host. The dialogue between Mycobacterium tuberculosis and the host is becoming understandable at the molecular, cellular, and tissue level. This has led to the elucidation of the (i) interaction between pattern recognition receptors and pathogen-associated molecular patterns, (ii) cross-talk between immune cells, and (iii) mechanisms underlying granuloma development. Disease as an eventual but not a necessary consequence of infection results from a sensitive balance between protective immunity and destructive pathology. Early events, governed largely by conserved mechanisms of host recognition, impact not only on type and course of adaptive immunity but also on lung parenchymal function. New interpretations of how these responses shape the lung environment and direct granuloma development emphasize that the ...
Central giant-cell granuloma - WikipediaCentral giant-cell granuloma - Wikipedia
Central giant-cell granuloma (CGCG) is a benign condition of the jaws. It is twice as likely to affect women and is more likely to occur in 20- to 40-year-old people. Central giant-cell granulomas are more common in the mandible and often cross the midline. CGCG lesions are found more commonly in the anterior of the maxilla and the mandible in younger people (before age 20). They are characterized by large lesions that expand the cortical plate and can resorb roots and move teeth. They are composed of multi-nucleated giant cells. CGCG has a slight predilection for females. Radiographically : It appears as multilocular radiolucencies of bone.The margin of the lesion has scalloped appearance and is well demarcated. Resorption and divergence of roots is also seen. There are two types of CGCGs, non-aggressive and aggressive. The former has a slow rate of growth and thus less likely to resorb roots and perforate the cortical plate. The aggressive form has rapid growth and thus is much more likely to ...
Data Availability StatementAll relevant data are within the paper. or NTB. - BRAF inhibitors on Immune-based antitumor therapyData Availability StatementAll relevant data are within the paper. or NTB. - BRAF inhibitors on Immune-based antitumor therapy
Data Availability StatementAll relevant data are within the paper. or NTB. Finally, the circulating levels of all of the angiogenic elements examined were considerably reduced following effective chemotherapy. Conclusion As a result, our data demonstrate that PTB can be connected with elevated degrees of circulating angiogenic elements, probably reflecting vascular and endothelial dysfunction. Furthermore, a few of these circulating angiogenic elements could confirm useful as biomarkers to monitor disease intensity, bacterial burden and therapeutic responses. Intro Granulomatous inflammation can be characteristic of several autoimmune and infectious illnesses [1,2]. The tuberculous granuloma, a central feature in mycobacterial disease, may be the hallmark framework of tuberculosis (TB) disease and disease [1,2]. These granulomas are often seen as a the concomitant advancement of hypoxia, which functions as stimulus for vascularization [3]. Vascularization in animal types of TB offers been proven ...
Is granuloma associated with any other diseases? | Reference.comIs granuloma associated with any other diseases? | Reference.com
Granulomas are most commonly associated with infections, especially the fungal infection histoplasmosis, states Mayo Clinic. They are also associated with a primary immunodeficiency disease known as...
Benign granuloma of thyroid | Article about benign granuloma of thyroid by The Free DictionaryBenign granuloma of thyroid | Article about benign granuloma of thyroid by The Free Dictionary
Looking for benign granuloma of thyroid? Find out information about benign granuloma of thyroid. A discrete nodular lesion of inflammatory tissue in which granulation is significant. a focal growth of inflammatory origin in the cells of young connective... Explanation of benign granuloma of thyroid
Granuloma Formation around Filarial Larvae Triggered by Host Responses to an Excretory/Secretory Antigen | Infection and...Granuloma Formation around Filarial Larvae Triggered by Host Responses to an Excretory/Secretory Antigen | Infection and...
Over the past several years, our lab has been attempting to determine the mechanism by which inbred strains of mice, which we use as model mammalian hosts, respond to experimental filarial infections. The outcome of these studies indicates that an important host defense mechanism is the formation of multicellular aggregates of leukocytes called granulomas around incoming infectious larvae. Our previous studies indicated an important role for T cells (for the recruitment of a robust population of leukocytes and for activating macrophages along the alternative pathway of activation), B lymphocytes (particularly the B1 subset), and macrophages and eosinophils (for participating in the granulomas). We have demonstrated the crucial importance of antifilarial antibodies of the IgM isotype in binding to the surface of the larvae and facilitating the adhesion of activated macrophages to the larvae. We have further shown that the in vitro cytoadherence assay is a good surrogate for in vivo granuloma ...
Biology-Online • View topic - The Fiber DiseaseBiology-Online • View topic - The Fiber Disease
Both divinyl benzene copolymer (plastic) beads and schistosome eggs produce inflammatory reactions after intravenous deposition into the lung of a mouse. As reported previously, the schistosome egg granuloma is an immunologic reaction of the delayed hypersensitivity type; this inflammatory process is prevented by immunosuppressive measures, and characteristically demonstrates an anamnestic response. In contradistinction, the plastic bead granuloma appears to be characteristic of a foreign body reaction; it is unaffected by immunosuppressive measures and does not demonstrate an anamnestic response with repeated exposure. The data in this report suggest that the granuloma formation around plastic beads is a nonimmunologic reaction induced by chemical mediators of inflammation. This proposal is supported by the following findings: the plastic beads activate Hageman factor in normal human and mouse plasma; the plastic beads induce vascular permeability-enhancing activity as measured in guinea pig ...
Upregulation of IL-17A, CXCL9 and CXCL10 in Early-Stage Granulomas Induced by Mycobacterium bovis in Cattle - Surrey Research...Upregulation of IL-17A, CXCL9 and CXCL10 in Early-Stage Granulomas Induced by Mycobacterium bovis in Cattle - Surrey Research...
Science & Technology, Life Sciences & Biomedicine, Infectious Diseases, Veterinary Sciences, INFECTIOUS DISEASES, VETERINARY SCIENCES, tuberculosis, Mycobacterium bovis, cytokine, laser capture microdissection, qPCR, TUBERCULOUS GRANULOMA, GENE-EXPRESSION, PULMONARY GRANULOMAS, EFFECTOR FUNCTION, IMMUNE-RESPONSES, INFECTED CATTLE, GUINEA-PIGS, IN-VITRO, PATHOLOGY, CELLS ...
Lung Cancer - FreebooksLung Cancer - Freebooks
The DailyKos one of always could be embiggened him didnt take 4 phase lung cancer me and. An early stage cancer offers a better change of long-term survival than a late-stage cancer. In some cases however the underlying pathology of multiple ill-defined densities is interstitial disease, like in the alveolar form of sarcoidosis in which the granulomas are very small and fill up the alveoli. Youll learn what to do to counteract those causes. However, selecting ever-smokers for screening using individualized lung cancer risk calculations may be more effective and efficient than current USPSTF recommendations ...
Rainbow Wildlife Rescue: Avian Diseases ReferenceRainbow Wildlife Rescue: Avian Diseases Reference
GASTROINTESTINAL DISEASES OF BIRDS. James K Morrisey, DVM, DABVP (Avian). Diseases of the Oral Cavity. The oropharynx is a common site for a variety of lesions in birds. A thorough examination of the oral cavity is usually not possible in the awake parrot, however, a quick visual examination can be performed and the pet sedated if lesions are noted. Other species such as raptors, passerines, and columbiformes are more easily examined while awake. Clinical signs associated with oropharyngeal diseases vary, but may include halitosis, anorexia, inappetance, dysphagia, rubbing of the beak, or gaping.. Plaques or granulomas are a clinical sign common with several diseases including bacterial infections, yeast infections, hypovitaminosis A, parasitic diseases, and viral diseases. Cytology and culture of the lesion will help to determine the cause. Cytological samples may be collected by rubbing a sterile cotton-tipped applicator along the lesion and then rubbing the sample on a clean slide. Several ...
GRANULOMA GRAVIDICO PDFGRANULOMA GRAVIDICO PDF
... - control of pregnancy granuloma. . Avaliação clínica de acompanhamento após dois anos de controle de granuloma gravídico. . Luis Eduardo Rilling Nova.
Garnering Information on Granulomas | ScienceGarnering Information on Granulomas | Science
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neutralized calcified granuloma in brain - Neurology - MedHelpneutralized calcified granuloma in brain - Neurology - MedHelp
Dear doctor, Im 21yrs old.I dont have any health reoccuring disorders.. I have neutralized calcified granuloma at right hemisphere of my brain.. why is it formed?How it neutralized?how it long...
Новости - страница 4Новости - страница 4
CHEST 2013; 144(3):813-824 Clinical and Pathologic Analysis of 131 Patients With Completely Resected Nodules Background: The cause of pulmonary necrotizing granulomas is often unclear, even after histologic examination. Our aim was to determine the clinical signifi cance of histologically unexplained necrotizing granulomas. Methods: Pulmonary necrotizing granulomas surgically resected at the Mayo Clinic (1994-2004) / прочети повече ...
Granuloma, Respiratory Tract | Profiles RNSGranuloma, Respiratory Tract | Profiles RNS
This graph shows the total number of publications written about "Granuloma, Respiratory Tract" by people in this website by year, and whether "Granuloma, Respiratory Tract" was a major or minor topic of these publications ...
removal of stitch granulomaremoval of stitch granuloma
My doc did a 49020 but also removed a stitch granuloma that was the cause of the problem. Is the granuloma removal included in the 49020 or do I code
Silica Granuloma of Eyelid and Ocular Adnexa | JAMA Ophthalmology | JAMA NetworkSilica Granuloma of Eyelid and Ocular Adnexa | JAMA Ophthalmology | JAMA Network
• Seven cases of subcutaneous epithelioid granulomas caused by silica and involving the eyelids and periorbital region are described. Histologically, all cases
Granuloma gluteale infantum | DermNet NZGranuloma gluteale infantum | DermNet NZ
Granuloma gluteale infantum, infantile gluteal granulomata, vegetating bromidism. Authoritative facts about the skin from DermNet New Zealand.
Lick Granuloma in DogsLick Granuloma in Dogs
Lick Granuloma or Acral Lick Dermatitis is a real challenge for us in the veterinary world. . .at least it was for me until I entered the Alternative Medicine world and found the core cause of this problem. Let me show you how to fix this without spending hundreds of dollars and wasting lots of time. . .
Contact granuloma - LaryngopediaContact granuloma - Laryngopedia
A contact granuloma is a benign tissue reaction or growth, typically on the posterior third of the vocal cord, that occurs in response to injury.
Ciszta vagy granuloma eltávolításCiszta vagy granuloma eltávolítás
Az elhalt vagy gyökérkezelt fogak gyökércsúcsán ciszta vagy granuloma alakulhat ki. Ezen gócok mielőbbi eltávolítása kiemelkedően fontos. Tudjon meg többet!
new research findings two: Dirty Vaccines Every Human Vaccine Tested Was Contaminated With Meals and Debris in New Studynew research findings two: Dirty Vaccines Every Human Vaccine Tested Was Contaminated With Meals and Debris in New Study
As with anything small and foreign, its reaction to vaccine ingredients is potent, poorly understood, unpredictable, and as the Italian researchers say, may be "undesirable." The immune system may dispatch an army of large white blood cells called macrophages to engulf the foreign bodies and contain them in swellings and granulomas at the injection site. But if the contaminants are swept away in the bloods circulation to any distant site or organ including the microbiota, which regulate numerous functions including the immune system, their effect could be felt long after they covertly entered the body. ...
caseous granulomatous inflammation - Forum on Opportunistic Infections - TheBody.comcaseous granulomatous inflammation - Forum on Opportunistic Infections - TheBody.com
Caseous means cheese-like; granulomatous inflammation describes the arrangement in tissue of certain types of white blood cells in response to certain kinds of infections caused by mycobacteria or...
Transient hepatic fibrin-ring granulomas in a patient with acute hepatitis A - Yamamoto - 2008 - Liver - Wiley Online LibraryTransient hepatic fibrin-ring granulomas in a patient with acute hepatitis A - Yamamoto - 2008 - Liver - Wiley Online Library
If you are a society or association member and require assistance with obtaining online access instructions please contact our Journal Customer Services team ...
Granuloma InguinaleCME ActivityGranuloma InguinaleCME Activity
StatPearls and ETSU adhere to ACCME Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and ETSU that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved, and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.. The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patients medical condition.. ...
Granuloma - WikiMDGranuloma - WikiMD
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer ...
How to treat umbilical granuloma?How to treat umbilical granuloma?
Hello Doctor, I am 25 yrs old and married for the past 4 months. I have a |b|discharge from my navel|/b| for a year or so now. Its very smelly and yellow in color. I went to a surgeon who said that it was not cleaned properly and gave me betatdine solution. After applying it stopped for some days but then it has again started. Please let me know why this is happening and is it very serious? Also let me know whether I should consult a gynaecologist. Thanks, Priya
Expansively Hemorrhagic Foreign Body Granuloma at the Pelvis Caused by Microscopic MaterialsExpansively Hemorrhagic Foreign Body Granuloma at the Pelvis Caused by Microscopic Materials
A foreign body granuloma is a mass lesion consisting of a foreign body with host reaction. Its diagnosis is not always easy in respect of its similarity to soft tissue sarcoma. The most common foreign body is surgical sponge which can be detectable macroscopically. We present a foreign body granuloma in the left buttock caused by microscopic surgical materials that developed into a large lesion. An 80-year-old man with a history of surgery for dislocation of the left hip 20 years earlier, presented with a slowly growing mass that had expanded rapidly over the preceding 2 months. Histological examination revealed organizing granulation tissue surrounding the scattered foreign materials. One should be aware of foreign body granuloma at previously operated sites even without a retained macroscopic gauze sponge.
Granuloma | SemlerGranuloma | Semler
Usually a small red, oozing and bleeding bump, pyogenic granulomas appear as an overgrowth of tissue caused by irritation, physical trauma or hormonal factors. The most common locations for pyogenic granulomas are the head, neck, upper trunk, hands and feet. Although pyogenic granulomas are benign growths, sometimes cancer can mimic these nodules so your physician will likely order a biopsy to be safe. Children, pregnant women, and those taking certain medications have a higher chance of developing a pyogenic granuloma. ...
Peripheral giant-cell granuloma - WikipediaPeripheral giant-cell granuloma - Wikipedia
Peripheral giant-cell granuloma (PGCG) is an oral pathologic condition that appears in the mouth as an overgrowth of tissue due to irritation or trauma. Because of its overwhelming incidence on the gingiva, the condition is associated with two other diseases, though not because they occur together. Instead, the three are associated with each other because they appear frequently on gingiva: pyogenic granuloma and peripheral ossifying fibroma. Because of its similar microscopic appearance to the bony lesions called central giant-cell granulomas, peripheral giant-cell granulomas are considered by some researchers to be a soft tissue equivalent. The appearance of peripheral giant-cell granulomas is similar to pyogenic granulomas. The color ranges from red to bluish-purple, but is usually more blue in comparison to pyogenic granulomas. It can be sessile or pedunculated with the size usually being less than 2 cm. There is a gender difference with 60% of the disease occurring in females. The prevalence ...
Huggies Baby: GranulomaHuggies Baby: Granuloma
Granuloma - A granuloma is a little breadth of deepening in tissue due to injury, such as from an infection. Granulomas a lot of frequently appear in the lungs but can action in added locations of the physique as fit. Typically, a granuloma encompasses alone a tiny allotment of the tissue. For the a lot of part, a being with a granuloma does not acquaintance any signs or symptoms. Granulomas can be acquired by a array of biologic, actinic and concrete irritants of tissue. The a lot of accepted could could could cause of granuloma is histoplasmosis, a fungal infection that primarily affects the lungs. A lot of humans with pulmonary histoplasmosis never doubtable that they accept the disease ...
Allergic granulomatous angiitis synonyms, allergic granulomatous angiitis antonyms - FreeThesaurus.comAllergic granulomatous angiitis synonyms, allergic granulomatous angiitis antonyms - FreeThesaurus.com
Synonyms for allergic granulomatous angiitis in Free Thesaurus. Antonyms for allergic granulomatous angiitis. 4 words related to angiitis: angiopathy, inflammation, redness, rubor. What are synonyms for allergic granulomatous angiitis?
Histopathological and immunohistochemical characterisation of hepatic granulomas in Leishmania donovani-infected BALB/c mice: a...Histopathological and immunohistochemical characterisation of hepatic granulomas in Leishmania donovani-infected BALB/c mice: a...
The histopathological hallmark of hepatic resistance to visceralizing species of Leishmania is the development of functional granulomas [10, 11, 14]. Here we used IHC as a tool to characterise the different cells involved in the hepatic granuloma development at different stages of experimental VL in BALB/c mice, complemented by quantitative image analysis and detection of Leishmania antigen.. Immunohistochemical methods described here are a powerful tool to characterise host responses to infection in situ in mouse models of Leishmania spp. infection. These have also been used in other granulomatous diseases that share some, though not all properties with VL [15-18]. Additionally these techniques can be utilised to evaluate the cellular mechanism of new vaccines, drugs and treatment regimens [19-21]. Therefore this study provides in depth insights into the cellular dynamics of experimental VL in a context relevant to advancing health.. In agreement with previous studies [22, 23], we observed that ...
Medical Pictures Info - GranulomaMedical Pictures Info - Granuloma
Granuloma is a term in medical dictionary for a minute collection of immune cells which are known as macrophages. Granulomas figure while the immune system tries to wall off substances which it recognizes as foreign body but is not capable to remove. Such substances comprise infectious organisms like bacteria and fungi and other materials like sutureas well as keratin fragments. So, a granuloma is a particular kind of inflammation that can take place in a wide various kind of diseases. The adjective granulomatous means distinguishing by granulomas. All granulomas may contain extra cells and matrix. These contain neutrophils, lymphocytes, multinucleated giant cells, eosinophils, fibroblasts and collagen (fibrosis).. ...
Pyogenic Granuloma. Free Professional Reference | PatientPyogenic Granuloma. Free Professional Reference | Patient
Pyogenic Granuloma is also known as lobular capillary haemangioma and Pyogenic granulomata. Pyogenic Granuloma are common benign vascular lesions of the skin and mucosa.
Symptoms: Ear Fullness and Pressure : The Hearing JournalSymptoms: Ear Fullness and Pressure : The Hearing Journal
There are two theories for the development of a cholesterol granuloma. In the obstruction-vacuum theory, Eustachian tube dysfunction is thought to cause mucosal edema, which can result in repeated episodes of bleeding and subsequent formation of cysts surrounding the blood. The cysts gradually expand.. In the exposed marrow theory, on the other hand, hyperplastic mucosa is thought to invade underlying bone and expose the bone marrow, which, in turn, bleeds.. Either way, a combination of trapped blood and a surrounding chronic inflammatory response lead to the formation of a cholesterol granuloma. In our patient, the etiology is most likely related to Eustachian tube obstruction caused by previous surgery and radiation for a trigeminal schwannoma.. Histologically, cholesterol granulomas contain yellow-brown fluid consisting of cholesterol crystals, red blood cells, and blood break-down products.. Cholesterol granulomas are surrounded by a fibrous tissue capsule and can be located in any part of ...
Figure - Mycobacterium intermedium Granulomatous Dermatitis from Hot Tub Exposure - Volume 12, Number 5-May 2006 - Emerging...Figure - Mycobacterium intermedium Granulomatous Dermatitis from Hot Tub Exposure - Volume 12, Number 5-May 2006 - Emerging...
Nontuberculous mycobacteria, which are widespread in the environment, frequently cause opportunistic infections in immunocompromised patients. We report the first case of a patient with chronic granulomatous dermatitis caused by a rarely described organism, Mycobacterium intermedium. The infection was associated with exposure in a home hot tub.
Interstitial Granulomatous Dermatitis (Interstitial granulomatous dermatitis with arthritis, Ackermans syndrome, Ackermans...Interstitial Granulomatous Dermatitis (Interstitial granulomatous dermatitis with arthritis, Ackerman's syndrome, Ackerman's...
We offer clinical cancer updates, treatment guidance, and research news to the oncology nursing community. Visit us often for drug therapy testing results, patient care information and more. Download our FREE app today.
Sarcoidosis | Health Encyclopedia | FloridaHealthFinder.govSarcoidosis | Health Encyclopedia | FloridaHealthFinder.gov
The exact cause of sarcoidosis is unknown. What is known is that when a person has the disease, tiny clumps of abnormal tissue (granulomas) form in certain organs of the body. Granulomas are clusters of immune cells.. The disease can affect almost any organ. It most commonly affects the lungs.. Doctors think that having certain genes makes it more likely for a person to develop sarcoidosis. Things that may trigger the disease include infections with bacteria or viruses. Contact with dust or chemicals may also be triggers.. The disease is more common in African Americans and Caucasians of Scandinavian heritage. More women than men have the disease.. The disease often begins between ages 20 and 40. Sarcoidosis is rare in young children.. A person with a close blood relative who has sarcoidosis is nearly five times as likely to develop the condition. ...
Neurosarcoidosis: Background, Pathophysiology, EtiologyNeurosarcoidosis: Background, Pathophysiology, Etiology
Sarcoidosis is a multisystem disease process of unknown etiology whose pathogenesis involves formation of an inflammatory lesion known as a granuloma. Histologically, noncaseating granulomas are prominent in biopsies from lymph nodes or affected organs.
The Infections In Which Granulomas May Be Seen Are: Tuberculosis: In This Condition, The Granulomas Of Tuberculosis Contain...The Infections In Which Granulomas May Be Seen Are: Tuberculosis: In This Condition, The Granulomas Of Tuberculosis Contain...
We all have, sometime or the other, used and benefited from In this condition, the granulomas of tuberculosis contain caseating tubercles. Candidates last name was one of our best rated employees and proved and photos, while rendering additional options for sharing text, links, music, videos, and quotes. Dreamweaver CC comes with a completely amazing CSS Designer, that not only allows you to add and edit effects using a visual the mouth of jellyfish that are surrounded by the tentacles. For example, a sassafras tree leaf has tips for logical domain names tactics three lobes, but is will strike you the most is the bond shared by Atticus, a single parent, and his children, Scout and Jim. Initially, if you are starting on a limited and rather low will appear pixelated when you upload them on your site. This software helps you organize various pages on your birth date, phone number, email address, provocative pictures, etc.. Although the Apple iPhone comes preloaded with a whole lot of ...
Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissueModeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue
The widely used animal models for tuberculosis ( TB) display fundamental differences from human TB. Therefore, a validated model that recapitulates human lung TB is attractive for TB research. Here, we describe a unique method for establishment of TB infection in an experimental human lung tissue model. The model is based on cell lines derived from human lungs and primary macrophages from peripheral blood, and displays characteristics of human lung tissue, including evenly integrated macrophages throughout the epithelium, production of extracellular matrix, stratified epithelia and mucus secretion. Establishment of experimental infection in the model tissue with Mycobacterium tuberculosis, the bacterium that causes TB, resulted in clustering of macrophages at the site of infection, reminiscent of early TB granuloma formation. We quantitated the extent of granuloma formation induced by different strains of mycobacteria and validated our model against findings in other TB models. We found that ...
Pyogenic granuloma - Coordinated HealthPyogenic granuloma - Coordinated Health
Pyogenic granulomas are small, raised, red bumps on the skin. The bumps have a smooth surface and may be moist. They bleed easily because of the high number of blood vessels at the site.. ...
Treatment of Vocal Fold GranulomaTreatment of Vocal Fold Granuloma
Physicians have recently begun using a medical formulation of botulinum toxin, type A to treat vocal fold granulomas caused by overly forceful contact from vocal misuse or overuse. Botulinum toxin, type A, is injected into the muscle of the vocal fold to temporarily limit its mobility and thus decrease injury from forceful contact of vocal folds during voice misuse. This then leads to a decrease in irritation and inflammation allowing the granuloma to heal, as well as prevent new granuloma formation. Since the effects of botulinum toxin, type A injections are short-lasting (three to five months), they sometimes must be performed several times to achieve a desired result.. Injections of medical formulation of botulinum toxin, type A, for granuloma should be performed by a skilled otolaryngologist. (For more information, see Voice Care Team and Spasmodic Dysphonia.). ...
Midline Granuloma | Annals of Internal Medicine | American College of PhysiciansMidline Granuloma | Annals of Internal Medicine | American College of Physicians
To the editor: We were interested to read the paper, "Radiation Therapy of Midline Granuloma" by Fauci, Johnson, and Wolff (Ann Intern Med 84:140-147, 1976). They report, however, a concept and experience at variance with ours. Granulomatous lesions of the nose, as we have seen them, have usually been conveniently classifiable as either necrotizing granuloma with vasculitis consistent with Wegeners granulomatosis, polymorphic reticulosis ( 1 ), specific infectious granuloma, or lymphoma. The non-specific pathologic features referred to in the paper have suggested to us either that the biopsy was inadequate or that the disease process has not yet evolved into ...
Chapter 8 - Skin Cancer 909Chapter 8 - Skin Cancer 909
These are both vascular lesions, the former probably some form of hamartoma, the latter an abnormal vascular response to trauma. Haemangiomas such as the bright red Campbell de Morgan spots are extremely common and rarely get confused with anything more sinister. However in later life many people develop vascular papules or nodules that can mimic melanoma. If you can confidently remove the blood by pressure (and often the lesion will collapse and shrink temporarily in volume after you do this) you do not need to worry further. If not, you need advice. One variety referred to as a venous lake, is commonly seen on the lips, is easily compressible and is often confused with melanotic macules of the lips (which are not compressible).. Pyogenic granulomas are best viewed as a vascular proliferation in response to wounding, in which the vascular granulation tissue continues to grow inappropriately. They can occur in patients of any age, and at any body site but are most common on the fingers in the ...
Schistosomiasis granuloma formation - Schistosomiasis granuloma formationSchistosomiasis granuloma formation - Schistosomiasis granuloma formation
Afecțiunile fungice ale pielii, de regulă, sunt supuse numai tratamentului medicamentos, în timp ce se iau măsuri terapeutice anterioare, probabilitatea complicațiilor este mult mai mică. Goal: Evaluation of the impact of vitamin D deficiency on phospho-calcic metabolism and bone health in correlation with genetic factors in children and adolescents, ways of correction.
Granuloma formation induced by spines of the cactus, Opuntia a...Granuloma formation induced by spines of the cactus, Opuntia a...
Granuloma formation induced by spines of the cactus, Opuntia acanthocarpa.: Embedded cactus spines may cause immediate pain due to mechanical damage, be a sourc
More on Granuloma Annulare | Patient CareMore on Granuloma Annulare | Patient Care
For 1 month, a 25-year-old woman had experienced discomfort in and around the left eye and diplopia. She was in good health; she reported no weight loss, excessive nervousness, heat intolerance, decreased strength, changes in the texture of hair or skin, or altered bowel habits. There was no personal or family history of goiter or other thyroid disease. 1
More on Granuloma Annulare | Patient Care OnlineMore on Granuloma Annulare | Patient Care Online
For 1 month, a 25-year-old woman had experienced discomfort in and around the left eye and diplopia. She was in good health; she reported no weight loss, excessive nervousness, heat intolerance, decreased strength, changes in the texture of hair or skin, or altered bowel habits. There was no personal or family history of goiter or other thyroid disease.
GRANULOMA LETAL DE LA LINEA MEDIA PDFGRANULOMA LETAL DE LA LINEA MEDIA PDF
... - lymphomatoid granulomatosis a multisystem disease involving . maligno de la linea media, reticulosis polimorfa, granuloma letal de la linea media y.
DermIS - Granuloma Pyogenicum (information on the diagnosis)DermIS - Granuloma Pyogenicum (information on the diagnosis)
Pyogenic granuloma is a benign proliferative vascular tumour of the skin and mucous membrane that often follows a minor injury or infection. The tumour is usually solitary and preferentially located on the fingers, hands, forearms and face. It presents as a small erythematous papule that enlarges and often becomes pedunculated. Pyogenic granulomas bleed easily on minor trauma. Infection and ulceration with accompanying purulent exsudate may occur. ...
Headache, falling unconscious. CT scan showed calcified granuloma in left lobe. Serious? - Doctors insight on HealthcareMagicHeadache, falling unconscious. CT scan showed calcified granuloma in left lobe. Serious? - Doctor's insight on HealthcareMagic
Question - Headache, falling unconscious. CT scan showed calcified granuloma in left lobe. Serious?. Ask a Doctor about diagnosis, treatment and medication for Calcified granulomas, Ask a Neurologist
Child has umbilical granuloma, oozing, treated with silver nitrate. Can it wait? - Doctors insight on HealthcareMagicChild has umbilical granuloma, oozing, treated with silver nitrate. Can it wait? - Doctor's insight on HealthcareMagic
Question - Child has umbilical granuloma, oozing, treated with silver nitrate. Can it wait?. Ask a Doctor about diagnosis, treatment and medication for Umbilical granuloma, Ask a Pediatrician
Granuloma, Sterile in Lacey, WA | Dermatology Clinic for AnimalsGranuloma, Sterile in Lacey, WA | Dermatology Clinic for Animals
Granuloma, Sterile - Also Known As: Sterile granuloma, sterile pyogranuloma Transmission or Cause: Unknown, but thought to be an immune-mediated disease. Affected Animals:
Sarcoidosis 2001 | Postgraduate Medical JournalSarcoidosis 2001 | Postgraduate Medical Journal
Granulomas form by a stepwise series of events, starting when T helper cells recognise protein peptides presented to them by antigen presenting cells bearing histocompatibility class II molecules. Immunological reactivity or inflammation attract monocyte macrophages which fuse to form multinucleated giant cells and onwards to epithelioid cells. Granuloma formation is aided by a cavalcade of chemotactic factors; Th1 cells induce interleukin (IL)-2, interferon gamma, and tumour necrosis factor (TNF) with the help of IL-12 and costimulator B7. The resulting exuberant granuloma formation is associated with active cell mediated hypersensitivity and tissue destruction. This framework is also remodelled by chemokines, adhesion molecules, matrix receptors of the integrin family, costimulators B7 and CD28, IL-12, and RANTES (regulated on activation normal T cells as secreted).. Bronchoalveolar fluid (BALF) reveals this macrophage class II-CD4Th1 cell synergy with its awesome cytokine cascade. Angiotensin ...
Pet Portal : Southern Paws Animal HospitalPet Portal : Southern Paws Animal Hospital
How Is This Condition Diagnosed?. A lick granuloma is usually diagnosed by the appearance of the lesion and a history of the dog licking or chewing at the area. To determine the cause of the licking, your veterinarian may perform a number of tests, including skin scrapes (gently scraping the surface of the skin with a dull instrument to identify mites), skin cultures, skin biopsies (tissue samples), and blood work. He or she may also recommend a radiograph (x-ray) to see if there is a foreign body under the skin or if there has been trauma to the bone or joint beneath the lesion.. How Is a Lick Granuloma Treated?. Treatment for lick granuloma can take many months and usually requires some patience. If an underlying condition has been identified, treatment of this condition should help resolve the granuloma. Treatment may include medications such as antibiotics, antifungals, parasite treatment, antihistamines, pain medication, hormone supplements, or topical steroids.. Of course, preventing the ...
Susceptibility to tuberculosis: composition of tuberculous granulomas in Thorbecke and outbred New Zealand White rabbits | MetaSusceptibility to tuberculosis: composition of tuberculous granulomas in Thorbecke and outbred New Zealand White rabbits | Meta
Lymph nodes are part of the immune system and are spread throughout the body, draining lymph from various organs. Generating a spatial atlas of healthy human lymph nodes through single cell transcriptomics will gain insight into their complex biology. Discover the latest research on inferring cell interactions in human lymph nodes here. ...
Role of Cytokines in the Formation and Downregulation of Hepatic Circumoval Granulomas and Hepatic Fibrosis in Schistosoma...Role of Cytokines in the Formation and Downregulation of Hepatic Circumoval Granulomas and Hepatic Fibrosis in Schistosoma...
The granulomas around Schistosoma mansoni eggs cause most of the pathology of S. mansoni infections in immunologically competent a...
Videos - Hepatic Granulomas - Calcified | DrugsUpdate IndiaVideos - Hepatic Granulomas - Calcified | DrugsUpdate India
drugsupdate.com - Indias leading online platform for Doctors and health care professionals. Updates on Drugs, news, journals, 1000s of videos, national and international events, product-launches and much more...Latest drugs in India, drugs, drugs update, drugs update
Granulomas Following Subcutaneous Injection With AluminumGranulomas Following Subcutaneous Injection With Aluminum
Aluminum--based adjuvants induce persistent, sterile, subcutaneous granulomas with macrophage-driven translocation of aluminum to regional lymph nodes in sheep.
Chickenpox in unexplained pulmonary necrotizing granulomas<...Chickenpox in unexplained pulmonary necrotizing granulomas<...
TY - JOUR. T1 - Chickenpox in unexplained pulmonary necrotizing granulomas. AU - Rossi, Giulio. AU - Graziano, Paolo. AU - Cavazza, Alberto. PY - 2014/2. Y1 - 2014/2. UR - http://www.scopus.com/inward/record.url?scp=84893701466&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84893701466&partnerID=8YFLogxK. U2 - 10.1378/chest.13-2394. DO - 10.1378/chest.13-2394. M3 - Article. C2 - 24493548. AN - SCOPUS:84893701466. VL - 145. SP - 433. EP - 434. JO - Chest. JF - Chest. SN - 0012-3692. IS - 2. ER - ...
Quick Answer: Do Granulomas Bleed? - caramenggugurkankandungann.comQuick Answer: Do Granulomas Bleed? - caramenggugurkankandungann.com
Granuloma annulare is a rash that often looks like a ring of small pink, purple or skin-coloured bumps. It usually appears on the back of the hands, feet, elbows or ankles. The rash is not usually painful, but it can be slightly itchy. Its not contagious and usually gets better on its own within a few months ...
John Mayer Vocal Granuloma Surgery- Cancelled TourJohn Mayer Vocal Granuloma Surgery- Cancelled Tour
Dr. Reena Gupta, laryngologist (voice specialist), discusses vocal granuloma in light of John Mayers struggle after vocal surgery.
EOSINOTHILIC GRANULOMAEOSINOTHILIC GRANULOMA
Im trying to get more information on a disease or virus that affects the lungs called Eosinothilic Granuloma. The doctors and the American Lung Association dont know that much. Please e-mail me at Wendy_Harris at Harvard. edu ...
Pulmonary PathologyPulmonary Pathology
The histologic hallmark is caseating granulomata with Langhans type giant cells. The granuloma is a rounded collection of macrophages and lymphocytes containing multinucleated giant cells, the nuclei of which are arranged at the periphery in a horse-shoe shape.. ...
Treatment of rheumatoid arthritis | The BMJTreatment of rheumatoid arthritis | The BMJ
Is blockade of TNF-α the complete answer to treatment of rheumatoid arthritis? In terms of toxicity, anti-TNF-α agents fortunately have only produced side effects in line with their mode of action; infections are increased, and latent tuberculosis can be activated (partly by the known action of antitumour necrosis factor monoclonals on granulomas).22 It is, however, possible to screen and minimise the reactivation of tuberculosis with prophylaxis. Other problems include inducing antibodies against the drugs themselves and also switching to autoantibody production as is seen with Th2 cells. A greater problem is the need for ongoing therapy, which entails giving protein long term to patients, although it can now be a fully human monoclonal protein. Over time a finite loss of response occurs. Both a primary and a secondary non-response have been proposed for this complex mechanism.23 This is a particular problem in patients currently approved for therapy by the National Institute of Health and ...
Sterilization through Vaccination - Page 2 - Lawful Path ForumsSterilization through Vaccination - Page 2 - Lawful Path Forums
As with anything small and foreign, its reaction to vaccine ingredients is potent, poorly understood, unpredictable, and as the Italian researchers say, may be "undesirable." The immune system may dispatch an army of large white blood cells called macrophages to engulf the foreign bodies and contain them in swellings and granulomas at the injection site. But if the contaminants are swept away in the bloods circulation to any distant site or organ including the microbiota, which regulate numerous functions including the immune system, their effect could be felt long after they covertly entered the body ...
Sarcoid arthropathySarcoid arthropathy
Sarcoidosis, a multisystem disorder of unknown etiology, is characterized pathologically by the presence of noncaseating granulomas in affected organs (see). It typically affects young adults, and, although any organ may be affected, the disorder com
Health Care - Injectables - Chlamydia Bacterin Product Details - Sheepman Supply - Livestock Supply HeadquartersHealth Care - Injectables - Chlamydia Bacterin Product Details - Sheepman Supply - Livestock Supply Headquarters
For vaccinating healthy, susceptible sheep against Chlamydia Psittaci, a group of micro-organisms that cause enzootic abortion in ewes (EAE). Ewes should be vaccinated 60 days prior to breeding. Administer second dose 30 days later. Re-vaccinate anually. This vaccine may cause a granuloma at the site of injection. 60 day slaughter withdrawal. Note: This item is a refrigerated pharmaceutical. Please see our Shipping page for important information. ...
Identification of mycobacterial antigens activating and suppressing T-lymphocyte responses<...Identification of mycobacterial antigens activating and suppressing T-lymphocyte responses<...
TY - GEN. T1 - Identification of mycobacterial antigens activating and suppressing T-lymphocyte responses. AU - Ellner, J. J.. PY - 1989. Y1 - 1989. UR - http://www.scopus.com/inward/record.url?scp=0024836075&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0024836075&partnerID=8YFLogxK. M3 - Conference contribution. AN - SCOPUS:0024836075. SN - 0444813497. SP - 3. EP - 21. BT - Basic mechanisms of granulomatous inflammation: proceedings of the International Symposium on basic mechanisms of granulomatous inflammation. ICS851. A2 - Yoshida, T.. A2 - Torisu, M.. A2 - Yoshida, T.. A2 - Torisu, M.. PB - Elsevier Science Publishers B.V.. T2 - The International Symposium on basic mechanisms of granulomatous inflammation. Y2 - 28 November 1988 through 29 November 1988. ER - ...
Granulomatous (Crohns) Disease of the Upper Gastrointestinal Tract: A Study of 22 Patients with Mucosal GranulomasGranulomatous (Crohn's) Disease of the Upper Gastrointestinal Tract: A Study of 22 Patients with Mucosal Granulomas
We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.. ...
2009 Group 8 Project - CellBiology2009 Group 8 Project - CellBiology
Abscess - a localised collection of pus Eosinophilia - increased numbers of eosinophils circulating in the blood Fibrosis - the extensive deposition of connective tissue, particularly collagen, in an organ or tissue, that occurs as a part of the reparative process after substantial tissue destruction Gliosis - the process of repair and scar formation in the brain Granuloma - a focal collection of chronic inflammatory immune cells which forms when the immune system tries to wall of foriegn material but cannot eliminate. Necrosis is often found within the centre of a granuloma Hypoxic - an oxygen deficiency to the tissues or organs of the body Infarct - a circumscribed area of necrosis in a tissue or organ resulting from obstruction to blood flow Inflammation - a local response to cellular injury that serves as a mechanism to eliminate noxious agents and of damaged tissue and protect from further injury; may be acute or chronic - however when unqualified the term usually tends to refer to acute ...
2009 Group 8 Project - CellBiology2009 Group 8 Project - CellBiology
Abscess - a localised collection of pus Eosinophilia - increased numbers of eosinophils circulating in the blood Fibrosis - the extensive deposition of connective tissue, particularly collagen, in an organ or tissue, that occurs as a part of the reparative process after substantial tissue destruction Gliosis - the process of repair and scar formation in the brain Granuloma - a focal collection of chronic inflammatory immune cells which forms when the immune system tries to wall of foriegn material but cannot eliminate. Necrosis is often found within the centre of a granuloma Hypoxic - an oxygen deficiency to the tissues or organs of the body Infarct - a circumscribed area of necrosis in a tissue or organ resulting from obstruction to blood flow Inflammation - a local response to cellular injury that serves as a mechanism to eliminate noxious agents and of damaged tissue and protect from further injury; may be acute or chronic - however when unqualified the term usually tends to refer to acute ...
Granuloma InguinaleCME ActivityGranuloma InguinaleCME Activity
The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.. CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential ...
Vascular anomalyVascular anomaly
Interferon gammaInterferon gamma
Dog skin disordersDog skin disorders
Field stainField stain
Converse techniqueConverse technique
Morten Ansgar KveimMorten Ansgar Kveim
Charles DonovanCharles Donovan
Index of oral health and dental articlesIndex of oral health and dental articles
HistiocyteHistiocyte
PAS diastase stainPAS diastase stain
Domenico MajocchiDomenico Majocchi
NecrosisNecrosis
BlastomycosisBlastomycosis
Chest radiographChest radiograph
Merck stitch methodMerck stitch method
CryptitisCryptitis
GlochidGlochid
Inflammatory myofibroblastic tumourInflammatory myofibroblastic tumour
Testicular immunologyTesticular immunology
Idiopathic granulomatous hepatitisIdiopathic granulomatous hepatitis
Staphylococcal scalded skin syndromeStaphylococcal scalded skin syndrome
AbscessAbscess
Post-vasectomy pain syndromePost-vasectomy pain syndrome
Tattoo medical issuesTattoo medical issues
SarcoidosisSarcoidosis
Schistosoma haematobiumSchistosoma haematobium
Granulomatosis with polyangiitisGranulomatosis with polyangiitis
Xanthogranulomatous inflammationXanthogranulomatous inflammation
Gumma (pathology)Gumma (pathology)
List of infectious diseasesList of infectious diseases
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
GranulomaGranuloma, Foreign-BodyGranuloma, PyogenicEosinophilic GranulomaGranuloma, Respiratory TractGranuloma AnnulareGranuloma, Giant CellGranuloma InguinalePeriapical GranulomaGranuloma, LaryngealLiver Diseases, ParasiticSchistosomiasis mansoniTuberculomaSchistosoma mansoniSarcoidosisMycobacterium marinumSarcoidosis, PulmonaryLung Diseases, ParasiticSchistosomiasisGranuloma, Plasma CellPlasma Cell Granuloma, PulmonaryEpithelioid CellsGranuloma, Lethal MidlineGingival DiseasesLung DiseasesMycobacterium bovisOvumForeign-Body ReactionMycobacterium tuberculosisTuberculosis, HepaticMycobacterium InfectionsLungAntigens, HelminthCord FactorsMice, Inbred CBACalymmatobacteriumSkin DiseasesTuberculosisSchistosomaFacial DermatosesLiver DiseasesNeurocysticercosisMacrophagesTuberculosis, PulmonaryMycobacterium aviumSchistosomiasis japonicaPetrous BoneTuberculosis, Lymph NodeMycobacterium Infections, NontuberculousMice, Inbred C57BLBiopsyLiverSchistosoma japonicumTuberculosis, CutaneousSplenic DiseasesInterferon-gammaLip Diseases
granuloma or cancer?? - Dental Health - MedHelpgranuloma or cancer?? - Dental Health - MedHelp
removal of stitch granulomaremoval of stitch granuloma
Granuloma - WikipediaGranuloma - Wikipedia
neutralized calcified granuloma in brain - Neurology - MedHelpneutralized calcified granuloma in brain - Neurology - MedHelp
Is granuloma associated with any other diseases? | Reference.comIs granuloma associated with any other diseases? | Reference.com
Lick Granuloma in DogsLick Granuloma in Dogs
What is a Lung Granuloma?What is a Lung Granuloma?
How to treat umbilical granuloma?How to treat umbilical granuloma?
Granuloma gluteale infantum | DermNet NZGranuloma gluteale infantum | DermNet NZ
Letters to the Editor: Noninvasive Treatments for Umbilical Granulomas - American Family PhysicianLetters to the Editor: Noninvasive Treatments for Umbilical Granulomas - American Family Physician
Garnering Information on Granulomas | ScienceGarnering Information on Granulomas | Science
Transient hepatic fibrin-ring granulomas in a patient with acute hepatitis A - Yamamoto - 2008 - Liver - Wiley Online LibraryTransient hepatic fibrin-ring granulomas in a patient with acute hepatitis A - Yamamoto - 2008 - Liver - Wiley Online Library
Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule-1. | The Journal of...Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule-1. | The Journal of...
Granuloma Formation around Filarial Larvae Triggered by Host Responses to an Excretory/Secretory Antigen | Infection and...Granuloma Formation around Filarial Larvae Triggered by Host Responses to an Excretory/Secretory Antigen | Infection and...
Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type...Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type...
Lick granuloma - WikipediaLick granuloma - Wikipedia
Granuloma Inguinale | Summary | NNDSSGranuloma Inguinale | Summary | NNDSS
Granuloma - WikipediaGranuloma - Wikipedia
Granuloma Inguinale | 1997 Case DefinitionGranuloma Inguinale | 1997 Case Definition
Eosinophilic granuloma | pathology | Britannica.comEosinophilic granuloma | pathology | Britannica.com
Necrotizing granuloma: MedlinePlus Medical EncyclopediaNecrotizing granuloma: MedlinePlus Medical Encyclopedia
Granuloma annulare: MedlinePlus Medical EncyclopediaGranuloma annulare: MedlinePlus Medical Encyclopedia
Granuloma Inguinale (Donovanosis)Granuloma Inguinale (Donovanosis)
Granuloma Inguinale (Donovanosis) - 2015 STD Treatment GuidelinesGranuloma Inguinale (Donovanosis) - 2015 STD Treatment Guidelines
Granuloma annulare - WikipediaGranuloma annulare - Wikipedia
What causes eosinophilic granuloma (histiocytosis X)?What causes eosinophilic granuloma (histiocytosis X)?
Granuloma, Respiratory Tract[mh] - PubMed - NCBI"Granuloma, Respiratory Tract"[mh] - PubMed - NCBI
Warts and Granuloma Annulare | The BMJWarts and Granuloma Annulare | The BMJ
Causes of Pyogenic GranulomaCauses of Pyogenic Granuloma
EOSINOTHILIC GRANULOMAEOSINOTHILIC GRANULOMA
What are risk factors for granuloma annulare?What are risk factors for granuloma annulare?
Majocchi Granuloma: Background, Pathophysiology, EtiologyMajocchi Granuloma: Background, Pathophysiology, Etiology
Laryngeal granuloma definition | Drugs.comLaryngeal granuloma definition | Drugs.com
Lipophagic granuloma definition | Drugs.comLipophagic granuloma definition | Drugs.com
Lethal midline granuloma - Everything2.comLethal midline granuloma - Everything2.com
Granuloma Annulare | Johns Hopkins MedicineGranuloma Annulare | Johns Hopkins Medicine
Granuloma Faciale: Background, Pathophysiology, EtiologyGranuloma Faciale: Background, Pathophysiology, Etiology
Re: [Felvtalk] Eosinophilic granuloma in Spankys nasal passageRe: [Felvtalk] Eosinophilic granuloma in Spanky's nasal passage
The ultrastructure of granuloma annulare | SpringerLinkThe ultrastructure of granuloma annulare | SpringerLink
Ein Fall von Granuloma fungoides | SpringerLinkEin Fall von Granuloma fungoides | SpringerLink
Pyogenic Granuloma: Causes, Diagnosis, and TreatmentsPyogenic Granuloma: Causes, Diagnosis, and Treatments
Granuloma InguinaleGranuloma Inguinale
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
GranulomaGranuloma, Foreign-BodyGranuloma, PyogenicEosinophilic GranulomaGranuloma, Respiratory TractGranuloma AnnulareGranuloma, Giant CellGranuloma InguinalePeriapical GranulomaGranuloma, LaryngealLiver Diseases, ParasiticSchistosomiasis mansoniTuberculomaSchistosoma mansoniSarcoidosisMycobacterium marinumSarcoidosis, PulmonaryLung Diseases, ParasiticSchistosomiasisGranuloma, Plasma CellPlasma Cell Granuloma, PulmonaryEpithelioid CellsGranuloma, Lethal MidlineGingival DiseasesLung DiseasesMycobacterium bovisOvumForeign-Body ReactionMycobacterium tuberculosisTuberculosis, HepaticMycobacterium InfectionsLungAntigens, HelminthCord FactorsMice, Inbred CBACalymmatobacteriumSkin DiseasesTuberculosisSchistosomaFacial DermatosesLiver DiseasesNeurocysticercosisMacrophagesTuberculosis, PulmonaryMycobacterium aviumSchistosomiasis japonicaPetrous BoneTuberculosis, Lymph NodeMycobacterium Infections, NontuberculousMice, Inbred C57BLBiopsyLiverSchistosoma japonicumTuberculosis, CutaneousSplenic DiseasesInterferon-gammaLip Diseases
LesionsPyogenic granulomaInflammatoryInflammationPeripheral giant-celLesionBenignFeatures of granulomaTuberculosisPathologyDiagnosisNecrosisContact granulomaUmbilical granulomaHepaticSarcoidosisRelapsePlaquesLungInfectiousCutaneousCommonlyOccursTypicallyTissueInfectionFormationRarelyPyogenicumLymphocytesAntigenicSymptomsProducesPosteriorImmunologyTreatmentNodulesOccur
Lesions6
  • Examples of this use of the term granuloma are the lesions known as vocal cord granuloma (known as contact granuloma ), pyogenic granuloma and intubation granuloma, all of which are examples of granulation tissue , not granulomas. (wikipedia.org)
  • Granuloma gluteale infantum lesions are typically resistant to treatments with barrier creams , antifungal agents , and topical steroids . (dermnetnz.org)
  • On US studies, charcoal granulomas are characterized as irregular-shaped lesions, most often with hyperechogenicity and posterior shadowing. (jbsr.be)
  • We report cutaneous granulomas in a child with ataxia telangiectasia AT and compare the clinical course with similar lesions in an adult with common variable immunodeficiency CVI. (recardo.ru)
  • In either of these lesions, root canal resection is commonly used, which means that the cyst or granuloma is cleaned by the oral surgery method and the root tip is removed from which the process is started. (volomdental.hu)
  • Objectives Vocal fold granulomas are benign lesions of the larynx commonly caused by gastroesophageal reflux, intubation, and phonotrauma. (mcw.edu)
Pyogenic granuloma7
Inflammatory6
  • In terms of the underlying cause, the difference between granulomas and other types of inflammation is that granulomas form in response to antigens that are resistant to "first-responder" inflammatory cells such as neutrophils and eosinophils . (wikipedia.org)
  • Granuloma gluteale infantum may result in post- inflammatory hyperpigmentation and atrophic scarring. (dermnetnz.org)
  • Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule-1. (jimmunol.org)
  • Recent studies have demonstrated a crucial role for TNF during inflammatory granuloma formation. (jimmunol.org)
  • Acute schistosomiasis is characterized by pro-inflammatory responses against tissue- or organ-trapped parasite eggs along with granuloma formation. (biologists.org)
  • Consequently, FDG-PET hyperintensity due to charcoal-induced granuloma is very rarely observed, because initial FDG-PET/CT performed just after charcoal subcutaneous injection does not show any early inflammatory reaction, and most often tumor and needle tract are surgically removed before later PET-CT follow-up. (jbsr.be)
Inflammation3
  • A granuloma is a structure formed during inflammation that is found in many diseases. (wikipedia.org)
  • However, at longer term, charcoal particles will be ingested and slowly degraded by macrophages, inducing progressive inflammation reaction and, if it remains in situ for more than six months, substantial foreign body granulomas. (jbsr.be)
  • Current medical therapy includes inhaled corticosteroids to target inflammation that leads to granuloma formation. (mcw.edu)
Peripheral giant-cel1
  • Peripheral giant cell granuloma associated with dental implants: Black female patient, aged 20 years, after 6 months of orthodontic treatment presented to grannuloma private clinic complaining of gingival changes. (beyond-personal-training.com)
Lesion5
  • Pulmonary hyalinizing granuloma" is a lesion characterized by keloid -like fibrosis in the lung, and is not granulomatous. (wikipedia.org)
  • We have also assessed the increased expression of ICAM-1, its contribution to granuloma development, and its relationship with TNF during lesion formation. (jimmunol.org)
  • Increased steady state ICAM-1 mRNA expression was observed in primary egg granulomas when compared with normal lung and foreign body (Sephadex bead) granulomas, which suggests a role for ICAM-1 in Ag-induced lesion formation. (jimmunol.org)
  • In addition, passive immunization of mice with anti-ICAM-1 mAb during primary granuloma formation resulted in an attenuation of lesion development as compared with lesion development in a control Ab-treated group. (jimmunol.org)
  • The aim of this case report was to present a clinic case of gravidarum granuloma in the region of lower lingual gingiva, adjacent to an osseointegrated implant in a year-old woman, with 3 months of gestation, who had the lesion since the beginning of her pregnancy. (beyond-personal-training.com)
Benign2
Features of granuloma1
Tuberculosis1
Pathology1
Diagnosis1
Necrosis2
Contact granuloma5
Umbilical granuloma6
Hepatic1
  • Mice deficient in Cx3cr1 were protected from granuloma formation and hepatic injury induced by Schistosoma japonicum eggs, as manifested by reduced body weight loss and attenuated hepatomegaly along with preserved liver function. (biologists.org)
Sarcoidosis3
  • The antigen causing the formation of a granuloma is most often an infectious pathogen or a substance foreign to the body, but sometimes the offending antigen is unknown (as in sarcoidosis ). (wikipedia.org)
  • Pulmonary arterial hypertension occurs by two mechanisms in cardiac sarcoidosis: reduced left heart function due to granulomas weakening the heart muscle or from impaired blood flow. (recardo.ru)
  • It also frequently causes an increase in 1,dihydroxy vitamin D, the active metabolite of vitamin D , which is usually hydroxylated within the kidney, but in sarcoidosis patients, hydroxylation of vitamin D can occur outside the kidneys, namely inside the immune cells found in the granulomas the condition produces. (recardo.ru)
Relapse1
  • On cessation of oral steroids, significant relapse of the facial granuloma occurred. (recardo.ru)
Plaques1
Lung2
Infectious1
Cutaneous3
Commonly1
Occurs1
Typically2
Tissue4
  • The most accurate use of the term "granuloma" requires a pathologist to examine surgically removed and specially colored (stained) tissue under a microscope. (wikipedia.org)
  • A granuloma is a patch of inflamed tissue that has various causes, depending on its location in the body, but is most often caused by a fungal infection, a. (reference.com)
  • Very occasionally, when a bit of the granuloma detaches (see below), a person may cough up blood or a tiny piece of tissue. (laryngopedia.com)
  • If symptoms at any time during this wait are unacceptable (not usually the case), then the granuloma can be treated with laser ablation in a videoendoscopy laboratory or steroid injection into the abnormal tissue. (laryngopedia.com)
Infection3
  • Granulomas usually form in reaction to a low-grade, superficial skin infection in periumbilical crevasses and flourish in the moist environment afforded by today's large "super-absorbent" diapers that often cover up the area. (aafp.org)
  • In previous studies using a murine model of filarial infection, granuloma formation was found to be a most important host-protective mechanism. (asm.org)
  • We recommend the use of broad-spectrum antibiotics in conjunction with systemic steroids for progressive granulomas, as these patients are immunosuppressed and infection with an unidentified organism cannot be excluded. (recardo.ru)
Formation12
  • What causes formation of granuloma? (reference.com)
  • In the present study, we have examined the mechanism of TNF activation during Schistosoma mansoni egg granuloma formation and its relationship to the expression of ICAM-1. (jimmunol.org)
  • Our initial studies showed that high affinity human soluble TNFR coupled to the Fc portion of an Ig (sTNFR:Fc construct) could effectively diminish granuloma formation and lymphocyte activation in vivo. (jimmunol.org)
  • Subsequent studies have demonstrated that sTNFR:Fc treatment down-regulated granuloma formation and ICAM-1 expression, thus suggesting one mechanism of TNF involvement in granuloma formation was through the induction of ICAM-1. (jimmunol.org)
  • These data demonstrate that both TNF and ICAM-1 participate in lymphocyte activation and granuloma formation and suggest that one mechanism of TNF in granuloma development is through TNF-induced ICAM-1 expression. (jimmunol.org)
  • We have also shown that in vitro cytoadherence is a surrogate for the formation of antifilarial granulomas in vivo and that it requires "alternatively activated" host cells and a source of antifilarial antibody. (asm.org)
  • This and other aspects of the kinetics of formation of granulomas have led us to propose that granuloma formation is one, if not the most important, mechanism by which mammals defend themselves against large extracellularly dwelling pathogens. (asm.org)
  • A mutant mouse strain that has been particularly helpful in dissecting the mechanism of granuloma formation has been the secretory IgM knockout mouse (secIgM −/− mouse) ( 2 , 3 ). (asm.org)
  • This observation alerted us to the critical role of circulating antifilarial antibodies, particularly of the IgM isotype, in granuloma formation. (asm.org)
  • In the course of these studies, we found that the adherence of alternatively activated macrophages and eosinophils to infective larvae provides an in vitro surrogate for granuloma formation in vivo . (asm.org)
  • Here, we describe studies in Cx3cr1 −/− mice and demonstrate the role of Cx3cr1 in the pathoetiology of granuloma formation during acute schistosomiasis. (biologists.org)
  • If, however, a person's symptoms are too troublesome to wait for months, then the granuloma can be surgically removed, but while still leaving part of the stalk or base projecting from the surface, so as to avoid re-injuring the cartilage and perichondrium, which would provoke the formation of another granuloma. (laryngopedia.com)
Rarely1
  • A similar disorder, named granuloma gluteale adultorum, is rarely observed in bed-ridden adults with incontinence ( incontinence-associated dermatitis ). (dermnetnz.org)
Pyogenicum1
Lymphocytes1
  • Mice that are deficient in T lymphocytes (such as TCR α β knockout mice) ( 15 ), B1 B lymphocytes (such as CBA/N mice) ( 9 ), or both (such as SCID mice) ( 8 ) fail to form such granulomas. (asm.org)
Antigenic1
  • These data confirm that BmALT-2 is the antigenic target of granuloma-mediated killing of B. pahangi L3. (asm.org)
Symptoms2
  • If a calcified granuloma is causing symptoms, surgery may be necessary to remove it, according to Mayo Clinic. (reference.com)
  • Some individuals with contact granulomas have no symptoms whatsoever and only discover they have a granuloma while being examined for some other reason. (laryngopedia.com)
Produces1
Posterior1
  • Conclusion As the virtual granuloma size increased and the location became more posterior, glottic deposition and ideal particle size generally increased. (mcw.edu)
Immunology1
  • In cases of CGD, granulomas may develop due to the body's wounds being unable to properly heal, notes the American Academy of Allergy, Asthma and Immunology. (reference.com)
Treatment4
  • What is the treatment and outcome for granuloma gluteale infantum? (dermnetnz.org)
  • 1. Lotan G, Klin B, Efrati Y. Double-ligature: a treatment for pedunculated umbilical granulomas in children. (aafp.org)
  • 2 In reality, it is effective for large pedunculated granulomas and avoids a prolonged and usually unsuccessful trial of conservative treatment. (aafp.org)
  • Despite Dr. Wooltorton's observations, we still consider the double-ligature technique to be an attractive option for the treatment of pedunculated umbilical granulomas in children, when the conservative treatments fail. (aafp.org)
Nodules2
  • Granuloma gluteale infantum is a rare form of napkin dermatitis in which there are reddish-purple nodules in the napkin (diaper) area of infants. (dermnetnz.org)
  • Granuloma gluteale infantum is characterised by asymptomatic firm erythematous or violaceous nodules. (dermnetnz.org)
Occur1
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