Spinal Fusion: Operative immobilization or ankylosis of two or more vertebrae by fusion of the vertebral bodies with a short bone graft or often with diskectomy or laminectomy. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p236; Dorland, 28th ed)Spinal Cord: A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.Scoliosis: An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed)Lumbar Vertebrae: VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).Spinal DiseasesOrthopedic Fixation Devices: Devices which are used in the treatment of orthopedic injuries and diseases.Bone Transplantation: The grafting of bone from a donor site to a recipient site.Membrane Fusion: The adherence and merging of cell membranes, intracellular membranes, or artificial membranes to each other or to viruses, parasites, or interstitial particles through a variety of chemical and physical processes.Graft Survival: The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.Spine: The spinal or vertebral column.Cell Fusion: Fusion of somatic cells in vitro or in vivo, which results in somatic cell hybridization.Pseudarthrosis: A pathologic entity characterized by deossification of a weight-bearing long bone, followed by bending and pathologic fracture, with inability to form normal BONY CALLUS leading to existence of the "false joint" that gives the condition its name. (Dorland, 27th ed)Ilium: The largest of three bones that make up each half of the pelvic girdle.Spinal Stenosis: Narrowing of the spinal canal.Laminectomy: A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.Bone Screws: Specialized devices used in ORTHOPEDIC SURGERY to repair bone fractures.Thoracic Vertebrae: A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.Recombinant Fusion Proteins: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.Bone Substitutes: Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.Spondylolisthesis: Forward displacement of a superior vertebral body over the vertebral body below.Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.Kyphosis: Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.Internal Fixators: Internal devices used in osteosynthesis to hold the position of the fracture in proper alignment. By applying the principles of biomedical engineering, the surgeon uses metal plates, nails, rods, etc., for the correction of skeletal defects.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Ceramics: Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Sacrum: Five fused VERTEBRAE forming a triangle-shaped structure at the back of the PELVIS. It articulates superiorly with the LUMBAR VERTEBRAE, inferiorly with the COCCYX, and anteriorly with the ILIUM of the PELVIS. The sacrum strengthens and stabilizes the PELVIS.Injections, Spinal: Introduction of therapeutic agents into the spinal region using a needle and syringe.Spondylosis: A degenerative spinal disease that can involve any part of the VERTEBRA, the INTERVERTEBRAL DISK, and the surrounding soft tissue.Spondylolysis: Deficient development or degeneration of a portion of the VERTEBRA, usually in the pars interarticularis (the bone bridge between the superior and inferior facet joints of the LUMBAR VERTEBRAE) leading to SPONDYLOLISTHESIS.Intervertebral Disc Displacement: An INTERVERTEBRAL DISC in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.Bone Regeneration: Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.Spinal Nerves: The 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment. The spinal nerve plexuses and the spinal roots are also included.Spinal Cord Diseases: Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.Meningomyelocele: Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)Cervical Vertebrae: The first seven VERTEBRAE of the SPINAL COLUMN, which correspond to the VERTEBRAE of the NECK.Intervertebral Disc: Any of the 23 plates of fibrocartilage found between the bodies of adjacent VERTEBRAE.Viral Fusion Proteins: Proteins, usually glycoproteins, found in the viral envelopes of a variety of viruses. They promote cell membrane fusion and thereby may function in the uptake of the virus by cells.Anesthesia, Spinal: Procedure in which an anesthetic is injected directly into the spinal cord.Gene Fusion: The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.Spinal Curvatures: Deformities of the SPINE characterized by abnormal bending or flexure in the vertebral column. They may be bending forward (KYPHOSIS), backward (LORDOSIS), or sideway (SCOLIOSIS).Tuberculosis, Spinal: Osteitis or caries of the vertebrae, usually occurring as a complication of tuberculosis of the lungs.Spinal Nerve Roots: Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.Spinal Cord Neoplasms: Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.Spinal Canal: The cavity within the SPINAL COLUMN through which the SPINAL CORD passes.Prostheses and Implants: Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.Spinal Cord Compression: Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Osteogenesis: The process of bone formation. Histogenesis of bone including ossification.Calcium Phosphates: Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.Decompression, Surgical: A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)Spinal NeoplasmsLow Back Pain: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Hospital Medicine: The branch of medicine concerned with the delivery of comprehensive medical care to hospitalized patients. Practitioners include physicians and non-physician providers who engage in clinical care, teaching, research, or leadership in the field of general hospital medicine.(from http://www.hospitalmedicine.org/AM/Template.cfm?Section=Hospitalist_Definition)Oncogene Proteins, Fusion: The GENETIC TRANSLATION products of the fusion between an ONCOGENE and another gene. The latter may be of viral or cellular origin.Spinal Fractures: Broken bones in the vertebral column.Transplantation, Autologous: Transplantation of an individual's own tissue from one site to another site.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.Pain Measurement: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.Bone Demineralization Technique: Removal of mineral constituents or salts from bone or bone tissue. Demineralization is used as a method of studying bone strength and bone chemistry.Diskectomy: Excision, in part or whole, of an INTERVERTEBRAL DISC. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.Lumbosacral Region: Region of the back including the LUMBAR VERTEBRAE, SACRUM, and nearby structures.Cost Allocation: The assignment, to each of several particular cost-centers, of an equitable proportion of the costs of activities that serve all of them. Cost-center usually refers to institutional departments or services.Bone Morphogenetic Protein 2: A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into OSTEOBLASTS.Pain, Postoperative: Pain during the period after surgery.Spondylitis: Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)Orthopedic Procedures: Procedures used to treat and correct deformities, diseases, and injuries to the MUSCULOSKELETAL SYSTEM, its articulations, and associated structures.Back Pain: Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.Spinal Injuries: Injuries involving the vertebral column.Polytetrafluoroethylene: Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.Blood Loss, Surgical: Loss of blood during a surgical procedure.Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)Surgical Wound Infection: Infection occurring at the site of a surgical incision.Intervertebral Disc Degeneration: Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.Absorbable Implants: Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)Postoperative Care: The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)Braces: Orthopedic appliances used to support, align, or hold parts of the body in correct position. (Dorland, 28th ed)Spinal Cord Ischemia: Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.Electric Stimulation Therapy: Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.Disability Evaluation: Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Ganglia, Spinal: Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.X-Ray Microtomography: X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.Neuromuscular Diseases: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Traction: The pull on a limb or a part thereof. Skin traction (indirect traction) is applied by using a bandage to pull on the skin and fascia where light traction is required. Skeletal traction (direct traction), however, uses pins or wires inserted through bone and is attached to weights, pulleys, and ropes. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed)Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Preoperative Period: The period before a surgical operation.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Stockings, Compression: Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.Biomechanical Phenomena: The properties, processes, and behavior of biological systems under the action of mechanical forces.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Vascular Patency: The degree to which BLOOD VESSELS are not blocked or obstructed.Motor Neurons: Neurons which activate MUSCLE CELLS.Orthopedics: A surgical specialty which utilizes medical, surgical, and physical methods to treat and correct deformities, diseases, and injuries to the skeletal system, its articulations, and associated structures.Paraplegia: Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.Polyethylene Terephthalates: Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.Bone Morphogenetic Proteins: Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.Saphenous Vein: The vein which drains the foot and leg.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Kidney Transplantation: The transference of a kidney from one human or animal to another.Blood Vessel Prosthesis Implantation: Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.Range of Motion, Articular: The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.Oncogene Fusion: The GENETIC RECOMBINATION of the parts of two or more GENES, including an ONCOGENE as at least one of the fusion partners. Such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS.Fracture Healing: The physiological restoration of bone tissue and function after a fracture. It includes BONY CALLUS formation and normal replacement of bone tissue.Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Bone Remodeling: The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.Alendronate: A nonhormonal medication for the treatment of postmenopausal osteoporosis in women. This drug builds healthy bone, restoring some of the bone loss as a result of osteoporosis.Veins: The vessels carrying blood away from the capillary beds.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Hematoma, Epidural, Spinal: A rare epidural hematoma in the spinal epidural space, usually due to a vascular malformation (CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS) or TRAUMA. Spontaneous spinal epidural hematoma is a neurologic emergency due to a rapidly evolving compressive MYELOPATHY.Posterior Horn Cells: Neurons in the SPINAL CORD DORSAL HORN whose cell bodies and processes are confined entirely to the CENTRAL NERVOUS SYSTEM. They receive collateral or direct terminations of dorsal root fibers. They send their axons either directly to ANTERIOR HORN CELLS or to the WHITE MATTER ascending and descending longitudinal fibers.Primary Graft Dysfunction: A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Weight-Bearing: The physical state of supporting an applied load. This often refers to the weight-bearing bones or joints that support the body's weight, especially those in the spine, hip, knee, and foot.Spinal Muscular Atrophies of Childhood: A group of recessively inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)Liver Transplantation: The transference of a part of or an entire liver from one human or animal to another.Transplants: Organs, tissues, or cells taken from the body for grafting into another area of the same body or into another individual.Cost-Benefit Analysis: A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Fractures, Bone: Breaks in bones.Spinal Cord Regeneration: Repair of the damaged neuron function after SPINAL CORD INJURY or SPINAL CORD DISEASES.Activities of Daily Living: The performance of the basic activities of self care, such as dressing, ambulation, or eating.Wound Healing: Restoration of integrity to traumatized tissue.Analgesia, Patient-Controlled: Relief of PAIN, without loss of CONSCIOUSNESS, through ANALGESIC AGENTS administered by the patients. It has been used successfully to control POSTOPERATIVE PAIN, during OBSTETRIC LABOR, after BURNS, and in TERMINAL CARE. The choice of agent, dose, and lockout interval greatly influence effectiveness. The potential for overdose can be minimized by combining small bolus doses with a mandatory interval between successive doses (lockout interval).Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Recovery of Function: A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.Quadriplegia: Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.Nerve Regeneration: Renewal or physiological repair of damaged nerve tissue.Green Fluorescent Proteins: Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Outcome Assessment (Health Care): Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).Hospital Costs: The expenses incurred by a hospital in providing care. The hospital costs attributed to a particular patient care episode include the direct costs plus an appropriate proportion of the overhead for administration, personnel, building maintenance, equipment, etc. Hospital costs are one of the factors which determine HOSPITAL CHARGES (the price the hospital sets for its services).Cell Line: Established cell cultures that have the potential to propagate indefinitely.Trigeminal Nucleus, Spinal: Nucleus of the spinal tract of the trigeminal nerve. It is divided cytoarchitectonically into three parts: oralis, caudalis (TRIGEMINAL CAUDAL NUCLEUS), and interpolaris.
... and beta-tricalcium phosphate mixed with bone marrow aspirate as a bone graft substitute for posterolateral spinal fusion". ... It can be used as a tissue replacement for repairing bony defects when autogenous bone graft is not feasible or possible. It ... Moore DC, Chapman MW, Manske D (1987). "The evaluation of a biphasic calcium phosphate ceramic for use in grafting long-bone ... It may also be combined with autologous materials for a bone graft. Porous beta-Tricalcium phosphate scaffolds are employed as ...
Management of scoliosis
New implants that aim to delay spinal fusion and to allow more spinal growth in young children have been developed. For the ... Thoracoplasty may also be performed to obtain bone grafts from the ribs instead of the pelvis, regardless of whether a rib hump ... In general, modern spinal fusions have good outcomes with high degrees of correction and low rates of failure and infection. ... Spinal fusion is the most widely performed surgery for scoliosis. In this procedure, bone [either harvested from elsewhere in ...
Posterolateral fusion for isthmic spondylolisthesis in adults: Analysis of fusion rate and clinical results. Journal of Spinal ... The bone grafts complete their fusion in 4-8 months following the surgery, securing the spine in the correct position. The ... There are two main types of surgery for this condition: Spinal fusion: This procedure is recommended when a set of vertebrae ... to control and limit spinal movement, and reduce stress on the injured spinal segment. Bracing immobilizes the spine in a ...
Fred H. Albee
Albee discovered a method for using bone instead of metal to perform a spinal fusion for infected vertebrae. He perfected his ... He later applied the principles of grafting, and guarding a tree from outside disruptions, to his bone grafting operations. ... Albee was born on a farm in the township of Alna, Maine, on a Friday the 13th, and learned how to do tree grafting from his ... Albee's 1915 textbook, Bone Graft Surgery, came out as the War ended its second year. At least 70 percent of war wounds in ...
There are many types of spinal fusion and each technique involves using bone grafting-either from the patient (autograft), ... Interbody Fusion is a graft where the entire intervertebral disc between vertebrae is removed and a bone graft is placed in the ... Spinal fusion is most commonly performed to relieve the pain and pressure on the spinal cord that results when a disc ( ... Lumbar and cervical spinal fusions are more commonly performed than thoracic fusions. Degeneration happens more frequently ...
Sacroiliac joint dysfunction
A fixation of the joint (screws or similar hardware only, without the use of bone grafting) is more common than a spinal fusion ... There is also a notable incidence of lumbar spinal fusion patients that present with sacroiliac pain and hypermobility, ... Mixter, WJ; Barr, JS (1934). "Rupture of the Intervertebral Disc with Involvement of the Spinal Canal". N Engl J Med. 211: 210- ... Clinical studies have found up to 75% of post-lumbar fusion patients develop SI joint degeneration within five years of surgery ...
Icahn School of Medicine at Mount Sinai
... for spinal fusion in Money Magazine Diane E. Meier, geriatrician and MacArthur Fellow, 2008 David Muller, co-founder of the ... and Graft-Vs.-Host Disease: Immunology, Pathophysiology, and Treatment (1990), and the Director of Mount Sinai Hospital's ... United States to perform minimally invasive aortic aneurysm surgery and one of the first to perform a successful stent graft ...
... replacement Reconstruction due to cancer or trauma Ridge augmentation in dental procedures Shoulder repair Spinal fusion ... and the term homovital graft might be used in reference to grafts whose cells must continue to grow and reproduce for the graft ... These grafts persist however as homostatic grafts and are completely replaced by host tissues in time.) "Composite Tissue ... Unlike allografts, such grafts do not corporate into the body. As with many operations, allotransplantation also has some side ...
Anterior cervical discectomy and fusion
The slow process of the bone graft joining the vertebrae together is called "fusion". Sometimes a titanium plate is screwed on ... Anterior cervical discectomy and fusion (ACDF) is a surgical procedure to treat nerve root or spinal cord compression by ... The disc material, pressing on the spinal nerve or spinal cord, is then completely removed. The intervertebral foramen, the ... The patient may be advised to wear a neck brace or collar (for up to 8 weeks) that serves to ensure proper spinal alignment. ...
... spinal fusion surgery may be performed. Spinal fusion is a procedure in which bone grafts and metal hardware is used to fix ... A mutli-level laminectomy can be done to widen the spinal canal in the case of spinal stenosis. A foraminotomy or foraminectomy ... Non-radicular back pain is most commonly caused by injury to the spinal muscles or ligaments, degenerative spinal disease, or a ... Causes of neurological deficits can include spinal disc herniation, spinal stenosis, degenerative disc disease, tumor, ...
List of MeSH codes (E04)
... spinal fusion MeSH E04.555.110 --- arthroplasty MeSH E04.555.110.110 --- arthroplasty, replacement MeSH E04.555.110.110.054 ... bone-patellar tendon-bone graft MeSH E04.555.200 --- diskectomy MeSH E04.555.200.200 --- diskectomy, percutaneous MeSH E04.555. ... bone-patellar tendon-bone graft MeSH E04.936.450.475 --- heart transplantation MeSH E04.936.450.475.450 --- heart-lung ...
Spinal fusion is an example of adjacent vertebrae connected allowing them to grow together into one piece. modifying the ... Although grafting is often used in cosmetic surgery, it is also used in other surgery. Grafts may be taken from one area of the ... Spinal anesthesia may be used when the surgical site is too large or deep for a local block, but general anesthesia may not be ... With local and spinal anesthesia, the surgical site is anesthetized, but the patient can remain conscious or minimally sedated ...
Spinal fusion was one of the five most common OR procedures performed in every age group except infants younger than 1 year and ... Orthopaedic Surgeons American Osteopathic Board of Orthopedic Surgery Arbeitsgemeinschaft für Osteosynthesefragen Bone grafting ... Shoulder arthroscopy and debridement Lumbar spinal fusion Repair fracture of the distal part of radius Low back intervertebral ... Though, as the name implies, the discipline was initially developed with attention to children, the correction of spinal and ...
ICD-9-CM Volume 3
Spinal fusion (81.1) Arthrodesis and arthroereisis of foot and ankle (81.2) Arthrodesis of other joint (81.3) Refusion of spine ... Full-thickness skin graft to hand (86.62) Other skin graft to hand (86.63) Full-thickness skin graft to other sites (86.64) ... Diagnostic procedures on spinal cord and spinal canal structures (03.31) Spinal tap (04) Operations on cranial and other nerves ... Operations on spinal cord and spinal canal structures (03.0) Exploration and decompression of spinal canal structures (03.09) ...
Degenerative disc disease
"Mesoblast files spinal fusion IND". Australian Life Scientist. 2006-11-27. Archived from the original on 2009-01-08. Retrieved ... A bone graft, and in some cases a metal plate and screws, is used to stabilize the spine. Dynamic Stabilisation: Following a ... Spinal laminectomy: A procedure for treating spinal stenosis by relieving pressure on the spinal cord. A part of the lamina is ... The spinal canal is then reconstructed to make more room for the spinal cord. Laminotomy: A procedure that removes only a small ...
Robert Thomas Grotz
"Linearly expanding spine cage for enhanced spinal fusion". United States patent and Trademark Office US7,819,921. Retrieved ... "Selectively expanding spine cage with enhanced bone graft infusion". United States patent and Trademark Office US9,028,550. ... "Linearly expanding spine cage for enhanced spinal fusion". United States patent and Trademark Office US7,819,921. Retrieved ... "Linearly expanding spine cage for enhanced spinal fusion". United States patent and Trademark Office US7,722,674. Retrieved ...
This bone graft holds the remaining vertebrae apart. As it heals, the vertebrae grow together and fuse. "Cervical Corpectomy". ... When the vertebral body has been removed, the surgeon performs a vertebral fusion. Because a space in the column remains from ... usually as a way to decompress the spinal cord and nerves. Corpectomy is often performed in association with some form of ...
Spinal fusion is an example of adjacent vertebrae connected allowing them to grow together into one piece. ... Although grafting is often used in cosmetic surgery, it is also used in other surgery. Grafts may be taken from one area of the ... Spinal anesthesia may be used when the surgical site is too large or deep for a local block, but general anesthesia may not be ... grafts - may be severed pieces of tissue cut from the same (or different) body or flaps of tissue still partly connected to the ...
However, once the fusion is solidified, most patients can return to their usual lifestyle within one to two years. Spinal ... Normally, the damaged discs between the troubled vertebrae (wedged vertebrae) are removed and replaced with bone grafting from ... Scheuermann's disease can be successfully corrected with surgical procedures, almost all of which include spinal fusion and ... It causes backache and spinal curvature. In very serious cases it may cause internal problems and spinal cord damage, but these ...
Scott Spann (surgeon)
After a surgery that included an anterior and posterior fusion, an iliac bone graft and a Harm's Cage insertion, he underwent ... Scott Spann developed a company called Pantheon Spinal. Pantheon Spinal is a surgical device company dedicated to bringing ... Pantheon Spinal endeavors to redefine the way lateral access spinal surgery is performed - thus promoting better surgical ... Westlake Orthopaedics Spine & Sports Scott Spann MD Pantheon Spinal Starting a Device Company: 3 Steps from Dr. Scott Spann in ...
Paul O'Neill (rock producer)
Wikipedia:WikiProject Medicine/Cochrane/Cochrane Review List/Musculoskeletal, Oral, Skin and Sensory
Staples versus sutures for closing leg wounds after vein graft harvesting for coronary artery bypass surgery PMID 20464762 ... Positioning and spinal bracing for pain relief in metastatic spinal cord compression in adults PMID 26400848 https://doi.org/ ... Single or double-level anterior interbody fusion techniques for cervical degenerative disc disease PMID 21249667 https://doi. ... Skin grafting and tissue replacement for treating foot ulcers in people with diabetes PMID 26866804 https://doi.org/10.1002/ ...
Spinal fusion was one of the five most common OR procedures performed in every age group except infants younger than 1 year and ... Though, as the name implies, the discipline was initially developed with attention to children, the correction of spinal and ... such as John Hunter's research on tendon healing and Percival Pott's work on spinal deformity steadily increased the range of ... Bone grafting. *Orthotics. *List of orthopedic implants. ReferencesEdit. *^ Bois-Regard, Nicolas Andry de; Library, Classics of ...
... and the term homovital graft might be used in reference to grafts whose cells must continue to grow and reproduce for the graft ... Spinal fusion. *Urological procedures. *Skin transplants. *Corneal transplants. *Heart transplants. *Heart valves ... These grafts persist however as homostatic grafts and are completely replaced by host tissues in time.) ... W. P. Longmire, J. National Cancer Institute 14, 669: The term homostatic graft might be applied to inert tissues such as bone ...
Spinal fusion was one of the five most common OR procedures performed in every age group except infants younger than 1 year and ... Though, as the name implies, the discipline was initially developed with attention to children, the correction of spinal and ... such as John Hunter's research on tendon healing and Percival Pott's work on spinal deformity steadily increased the range of ... Bone grafting. *Computer Assisted Orthopedic Surgery. *Gait analysis. *Halo Brace. *Hand surgery ...
Cell grafting. Cell grafting in the early stages of embryo development has provided crucial information on cell fates and ... While the cells that remain as the neural tube form the brain and spinal cord, the other cells that were part of the neural ... With the neural plate having folded into a tube, the neural folds come together to complete the fusion of the neural tube. This ... Grafting experiments done in Xenopus and chicken embryos show the neural plate's capability to induce other regions of cells, ...
Icahn School of Medicine at Mount Sinai
Sean E. McCance, Clinical Professor of Orthopaedics and listed as one of the "Best Doctors" for spinal fusion in Money Magazine ... Steven J. Burakoff, cancer specialist, author of both Therapeutic Immunology (2001) and Graft-Vs.-Host Disease: Immunology, ... and one of the first to perform a successful stent graft procedure ...
"Comparison of perioperative outcomes and cost of spinal fusion for cervical trauma: weekday versus weekend admissions". Spine ( ... "Impact of nighttime and weekend liver transplants on graft and patient outcomes". Liver Transpl. 18: 558-65. doi:10.1002/lt. ... "Impact of nighttime and weekend liver transplants on graft and patient outcomes". Liver Transpl. 18: 558-65. doi:10.1002/lt. ... "The impact of weekend hospital admission on the timing of intervention and outcomes after surgery for spinal metastases". ...
... which can partially obstruct the flow of cerebro-spinal fluid from the neurocranium to the spinal cord. The Chiari ... The features of craniosynostosis' particular phenotype are determined by which suture is closed. The fusion of this suture ... A bone graft is placed in between the two halves of the supraorbital bars, thereby increasing the width between the orbits. ... A compensatory mechanism involves the movement of cerebrospinal fluid from the cranial vault towards the spinal cord. The ...
Olfactory ensheathing cells
Role in spinal cord injuriesEdit. Traumatic spinal cord damage causes a permanent loss of motor and sensory functions in the ... Transplantation of stem cells is also known to cause toxicity and graft-versus-host disease (GVHD). Apoptotic cells have been ... "CD46 on glial cells can function as a receptor for viral glycoprotein-mediated cell-cell fusion". Glia. 52 (3): 252-8. doi ... Transplantation of OECs into the spinal cord has become a possible therapy for spinal cord damage and other neural diseases in ...
Research comparing the effects of ankle replacement against ankle fusion (the TARVA study) is ongoing in the United Kingdom, in ... This procedure is becoming the treatment of choice for patients, replacing the conventional use of arthrodesis, i.e. fusion of ... "Prospective Controlled Trial of STAR Total Ankle Replacement Versus Ankle Fusion: Initial Results". Foot & Ankle International ...
سرطان پروستات - ویکیپدیا، دانشنامهٔ آزاد
Spinal cord compression can occur with metastases to the spine and can be treated with steroids, surgery, or radiation therapy ... In men who are candidates for active surveillance, fusion MR/US guided prostate biopsy detected 33% of cancers compared to 7% ... and AR into isolated samples of basal and luminal cells and grafted the treated tissue into mice. After 16 weeks, none of the ... Prostate cancer in the spine can also compress the spinal cord, causing tingling, leg weakness and urinary and fecal ...
Acute lymphoblastic leukemia
... also known as a spinal tap) can determine whether the spinal column and brain have been invaded. Brain and spinal column ... Examples of this include the ETV6-RUNX1 fusion gene that combines two factors that promote blood cell development and the BCR- ... The evidence is very uncertain about the therapeutic effect of mesenchymal stromal cells to treat graft-versus-host diseases ... The result is the combination of two usually separate proteins into a new fusion protein. This protein can have a new function ...
Anterior cruciate ligament reconstruction
Choice of graft. Type. Typically, age and lifestyle help determine the type of graft used for ACL reconstruction.[ ... Spinal fusion. *Intervertebral discs *Discectomy. *Annuloplasty. *Arthroplasty. Upper extremity. *Shoulder surgery *Shoulder ... Types of grafts. Grafts are inserted through a tunnel that is drilled through the shin bone (tibia) and thigh bone (femur ... With a hamstring graft, this number doubles, decreasing the risk of re-injury. The stiffness of a hamstring graft-quadruple ...
Spinal cord injuries are one of the most common traumas brought into veterinary hospitals. Spinal injuries occur in two ... Another stem-cell therapy called Prochymal, was conditionally approved in Canada in 2012 for the management of acute graft-vs- ... Brain and spinal cord injury. Stroke and traumatic brain injury lead to cell death, characterized by a loss of neurons ... Clinical and animal studies have been conducted into the use of stem cells in cases of spinal cord injury. ...
... which can partially obstruct the flow of cerebro-spinal fluid from the neurocranium to the spinal cord. The Chiari malformation ... The fusion of this suture causes a certain change in the shape of the skull; a deformity of the skull. Virchow's law dictates ... A bone graft is placed in between the two halves of the supraorbital bars, thereby increasing the width between the orbits. The ... New insights have given fuel to a debate whether there might be an intrinsic factor causing the premature fusion of the sutures ...
ಶಸ್ತ್ರಚಿಕಿತ್ಸೆ - ವಿಕಿಪೀಡಿಯ
Dual-energy X-ray absorptiometry
Femoral head ostectomy
Dual-energy X-ray absorptiometry
Ostra białaczka szpikowa, wolna encyklopedia
An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion ... The role of pattern-recognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell ... Immunohistochemistry and spinal projections of the reticular formation in the northern leopard frog, Rana pipiens.. „J Comp ... Mechanisms of the graft-versus-leukemia reaction. „Stem Cells". 15 (4), s. 248-58, 1997. DOI: 10.1002/stem.150248. PMID: ...
Spinal cord compression can occur with metastases to the spine and can be treated with steroids, surgery, or radiation therapy ... In men who are candidates for active surveillance, fusion MR/US guided prostate biopsy detected 33% of cancers compared to 7% ... and AR into isolated samples of basal and luminal cells and grafted the treated tissue into mice. After 16 weeks, none of the ... TMPRSS2-ETS gene family fusion, specifically TMPRSS2-ERG or TMPRSS2-ETV1/4 promotes cancer cell growth. Two large genome-wide ...
Comb PEGs have multiple PEG chains normally grafted onto a polymer backbone. The numbers that are often included in the names ... PEG is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene ... The possibility that PEG could be used to fuse nerve cells is being explored by researchers studying spinal cord injury. ... graft-Poly(ethylene glycol) in Aqueous Glycerol Mixtures". Tribology Letters. 37 (3): 541-552. doi:10.1007/s11249-009-9549-9. ...
Rejection of cutaneous grafts or transplantable tumors may be delayed. In addition, infection will increase the sensivity of ... It is then endocytosed into a vesicle inside the host cell and creates a fusion of the virus and vesicle membranes. The ... "a viral infection of the membranes surrounding the brain and spinal cord and of the cerebrospinal fluid". The name is based on ...
Bone Graft in Spinal Fusion Surgery
... bone graft provides a foundation or scaffold for the patients body to grow new bone. ... Bone graft doesnt heal or fuse the spine immediately; instead, ... The Role of Bone Graft in Spinal Fusion Surgery. Written by D. ... Bone graft refers to the use of bone in spinal fusion surgery. The purpose of a spinal fusion (arthrodesis) procedure is to ... Scaffold for New Bone Growth and Spinal Fusion. Bone graft doesnt heal or fuse the spine immediately; instead, bone graft ...
Bone Graft for Spinal Fusion Surgery
... but new biomedical materials are advancing the case for bone graft substitutes. ... Autograft and allograft are frequently used bone graft types for spinal fusion surgery, ... Spinal fusion is a very common back and neck surgery. In simplest terms, the goal of a spinal fusion is to fuse 2 spinal bones ... human bone autografts and allografts are the most common bone graft options for spinal fusion patients. However, bone graft ...
I had Spinal fusion l4 l5. Double bone graft to my facet joint in 2010. Now ive severe nerve damage?
Home › Q & A › Questions › I had Spinal fusion l4 l5..... I had Spinal fusion l4 l5. Double bone graft to my facet joint in ... muscle spasm, pain, neuralgia, nerves, bones, nerve, spinal fusion, bone. Details:. Ive always been active,for many years Ive ... I have had an anterior C4-6 fusion w/screws, plate and bone graft and a posterior scoliosis surgery?. Posted 11 Jan 2011 • 2 ... What dose of Celebrex is used for chronic low back pain one year after lumbar spinal fusion?. Posted 21 Jan 2017 • 2 answers ...
Additive Manufacturing and Bone Graft Enhancers in Spinal Fusion: An HSS Journal® Webinar | Orthogate
Cunningham will speak about the importance of surface technology and new strategies in enhancing spinal fusion. You... ... Additive Manufacturing and Bone Graft Enhancers in Spinal Fusion: An HSS Journal® Webinar ... Additive Manufacturing and Bone Graft Enhancers in Spinal Fusion: An HSS Journal® Webinar ... presents this webinar focused on innovative technologies in spinal fusion available today, including 3D printing and bone graft ...
Acute and Chronic Complications of Intracortical Iliac Crest Bone Grafting Versus the Traditional Corticocancellous Technique...
... it is known to cause significant graft-site morbidity. Unlike the traditional corticocancellous allograft, the intracortical ... Abstract Although autologous bone graft from the iliac crest is the gold standard for most spinal fusion applications, ... autologous bone grafting has become the most commonly used source of graft and is the gold standard for most spinal fusion ... autologous bone grafting has become the most commonly used source of graft and is the gold standard for most spinal fusion ...
Spinal Fusion: Understanding Bone Graft
... To fuse the spine, very small pieces of extra bone are needed. Called bone graft, this ... Bone graft comes from a bone bank or from your own body. Your surgeon will choose the type of graft thats best for you. ... The bone is also treated before it is used as a graft. The risk of getting a disease from bone graft is very slight. ... Bone may be taken through the incision made for your fusion, or through a separate incision. The area the bone is taken from ...
Bone Grafting - Spine Surgery - Infuse Bone Graft Evidence | Medtronic
... level 1 clinical evidence and preclinical evidence demonstrating the effectiveness and economic impact of Infuse Bone Graft ... Infuse™ Bone Graft/Perimeter™ Interbody Fusion Device. Infuse™ Bone Graft/Clydesdale™ Spinal System. Infuse™ Bone Graft/ ... Oblique Lateral Spinal System. The Infuse™ Bone Graft/Medtronic Interbody Fusion Device is indicated for spinal fusion ... Infuse™ Bone Graft/LT-Cage™ Lumbar Tapered Fusion Device. Infuse™ Bone Graft/Inter Fix™ Threaded Fusion Device. Infuse™ Bone ...
Bone Grafting - Spine and Orthopaedic - What Is It | Medtronic
... a procedure performed to replace bone or augment bone healing during orthopedic reconstruction and spinal fusion. ... BONE HEALING: SPINAL FUSION. Bone grafting is used with several common spinal fusion procedures, including:. *Fusion in the ... Possible Side Effects of Spinal Fusion with Bone Grafting. As with any surgery, surgical treatment is not without risk. A ... Bone grafts encourage bone formation to stabilize the spine and achieve the spinal fusion. ...
Spinal Fusion Ohio | Bone Grafting | Lumbar Spine Problems Ohio
Spinal fusion is a surgical procedure used to join two or more vertebrae together using a bone graft. Treatment for lumbar ... Spinal Fusion. What is a Decompression? :: What is a Spinal Fusion? :: Screws and Rods? :: Bone graft? ... Why is Spinal Fusion Done? Spinal fusion is done for many reasons. Most common reason is for severe arthritis in the neck or ... What is Spinal Fusion?. Spinal fusion is a surgical procedure used to join two or more vertebrae together. In a normal spine, ...
Is Topamax hurtful to someone that breaks bones or has oestoporosis?
Spinal Fusion with Implants: Bone Graft or Prosthetic? | Manfred F. Ricciardelli Jr., LLC
European Markets for Bone Graft Substitute Products for Spinal Fusion | Medical Device Market Research
The European market for bone graft substitute products for spinal fusion is projected to experience significant growth over the ... The European market for bone graft substitute products for spinal fusion is projected to experience significant growth over the ... In 2010, the value of the European market for bone graft substitute products for spinal fusion totaled approximately $177.1 ... Methodology Exhibit ES-1: Europe, Bone Graft Substitute Products for Spinal Fusion, Combined Market Forecast, 2010-2016 1. ...
Bone Grafts and Substitutes Market expected to reach USD 3.48 Billion Globally in 2023: Transparency Market Research
7, 2015-- According to a new market report published by Transparency Market Research Bone Grafts and Substitutes Market- Global ... Industry Analysis, Size, Share, Growth, Trends and Forecast, 2015- 2023, the global bone grafts and substitutes market was ... Synthetic bone grafts are majorly used in long bone and spinal fusion procedures. The spinal fusion application segment ... Bone grafts and substitutes are used in various application areas such as spinal fusion, foot and ankle, long bone, dental, ...
What bone graft alternatives are available for use in anterior spinal fusion procedures - Spine Secrets
What bone graft alternatives are available for use in anterior spinal fusion procedures. Fri, 02 May 2014 , Spine Secrets ... Both autograft and allograft bone graft have been reported to provide reasonable fusion rates in the anterior spinal column. ... Use of anterior and/or posterior spinal instrumentation can improve fusion rates when structural allograft bone grafts are used ... of fusion obtained with autograft must be weighed against the morbidity of harvesting large sections of autogenous bone graft ...
Patent US5824084 - Method of preparing a composite bone graft - Google Patents
The improved composite graft includes an enriched population of connective tissue progenitor cells and a greater number of ... The present invention also relates to a kit including the apparatus used for preparing the composite bone graft. ... The invention also relates to an improved composite bone graft prepared according to the present method. ... implantable substrate to provide a composite bone graft having an enriched population of connective tissue progenitor cells. ...
Spinal Fusion Surgery | Scoliosis and Spine Program | CHKD | Norfolk, VA
... spinal fusion surgery at CHKD is recommended when bracing or casting has been unable to stop the progression of a spinal curve ... What is bone grafting?. Bone grafting is used to help fuse the spine in the correct position. The source for the bone graft is ... What is posterior spinal fusion surgery?. A posterior spinal fusion is when an incision is made along the back. After the ... What is anterior spinal fusion surgery?. Anterior spinal fusion surgery is when the surgeon has to approach the spine from the ...
Ways To Perform Cervical Spinal Fusion & Its Associated Risks
Know more about Risks involved in cervical spinal fusion. ... Cervical spinal fusion is a technique used to stabilize the ... Bone graft. This method involves simulating the growth of a new bone by joining two adjacent bones in the vertebrae. The ... Risks involved in Cervical spinal fusion. There are a few risks associated with a cervical spinal fusion, and at times, there ... A cervical spinal fusion is also used as a follow-up treatment for spinal stenosis, disc hernia, rheumatoid arthritis, and ...
Bone Graft Materials Observational Registry - Full Text View - ClinicalTrials.gov
Spinal Fusion Patients who undergo a planned spinal fusion procedure requiring approved bone grafting materials (e.g., bone ... A Prospective Patient Registry for Bone Graft Substitutes in Spinal Fusion: Patient Outcomes and Use in Clinical Practice. ... Device: Bone graft substitute, autograft or allograft spine fusion surgery utilizing any commercially available bone graft ... Spinal Deformity Cervical Myelopathy Failed Back Surgery Syndrome Spinal Cord Neoplasms Device: Bone graft substitute, ...
Global Bone Graft Substitutes Market 2017 by top Manufacturers -... - FMR News
Report studies Bone Graft Substitutes in Global market that focuses on the top Manufacturers, Market Segment by Countries, ... 1.3 Bone Graft Substitutes Segment By Procedure Type. 1.3.1 Spinal Fusion. 1.3.2 Trauma Surgery. 1.3.3 Large-Joint Revision and ... global bone graft substitutes marketglobal bone graft substitutes market shareglobal bone graft substitutes market trendglobal ... 1 Bone Graft Substitutes Market Overview. 1.1 Product Overview and Scope of Bone Graft Substitutes. 1.2 Bone Graft Substitutes ...
Spinal Fusion - OrthoInfo - AAOS
Spinal fusion is a surgical procedure used to correct problems with the small bones of the spine (vertebrae). It is essentially ... Bone Grafting. All spinal fusions use some type of bone material, called a bone graft, to help promote the fusion. Generally, ... Fusion will take away some spinal flexibility, but most spinal fusions involve only small segments of the spine and do not ... To help you understand the main terms and abbreviations regarding spinal fusion, a glossary has been developed: Spinal Fusion ...
Patent US6676703 - Spinal fusion implant - Google Patents
An improved prosthetic implant for forming a rigid structure between adjoining vertebrae in a spinal column. The prosthetic ... Spinal implant having a passage for enhancing contact between bone graft material and cortical endplate bone. ... Systems and methods for spinal fusion. US8821553. Apr 19, 2006. Sep 2, 2014. X-Spine Systems, Inc.. Spinal fusion system ... Spinal implant adjustment. US20060195100 *. Apr 19, 2006. Aug 31, 2006. X-Spine Systems, Inc.. Spinal fusion system utilizing ...
Patent US7291149 - Method for inserting interbody spinal fusion implants - Google Patents
... forming a bore from the anterior or posterior aspect of the spinal column across a distracted disc space between the adjacent ... vertebral bodies and into the adjacent vertebral bodies, and inserting into the bore the spinal implant having opposed arcuate ... The present invention is directed to methods of inserting a variety of interbody spinal fusion implants across a disc space ... Itoman, M., et al.; Banked Bone Grafting for Bone Defect Repair-Clinical Evaluation of Bone Union and Graft Incorporation; J. ...
Human perivascular stem cell-based bone graft substitute induces rat spinal fusion. | MRC Centre for Regenerative Medicine
Human perivascular stem cell-based bone graft substitute induces rat spinal fusion. Title. Human perivascular stem cell-based ... All hPSC treatment groups induced successful spinal fusion, assessed by manual palpation and microcomputed tomography. ... it is not known whether hPSCs would be efficacious in a spinal fusion model. To investigate, we evaluated the osteogenic ... of freshly sorted hPSCs without culture expansion and differentiation in a rat model of posterolateral lumbar spinal fusion. We ...
Bone Graft: Purpose, Procedure & Risks
Bone grafting, or transplanting of bone tissue, is used to fix damaged bones or problem joints. Its also used for growing bone ... Spinal Fusion Surgery. Spinal fusion is a procedure that permanently joins two vertebrae into one solid bone. It treats ... After bone grafting. Recovery from bone grafts depends on the size of the graft and other variables. Typical recovery can take ... What is a bone graft?. A bone graft is a surgical procedure used to fix problems with bones or joints. Bone grafting, or ...
Effect of bone graft characterist... preview & related info | Mendeley
There is little information about the influence of bone graft size, position and elasticity on the mechanical behavior of the ... Spinal Fusion/standards. *Stress, Mechanical. *Support, Non-U.S. Govt. Get free article suggestions today. Mendeley saves you ... Though larger grafts lead to less contact pressure, it is difficult to judge the quality of different bone graft positions. In ... Cross-sectional area, position, and elastic modulus of the graft were varied in this study. Bone grafts, especially very stiff ...
fibrovascular Archives - AAPC Knowledge Center
IS ILIAC CREST BONE GRAFT STILL THE GOLD STANDARD IN SPINAL... : Spine Journal Meeting Abstracts
IS ILIAC CREST BONE GRAFT STILL THE GOLD STANDARD IN SPINAL FUSION SURGERY? A SURVEY OF SPINE SURGEONS: SP7.. Aubin, M. MD; Eck ... IS ILIAC CREST BONE GRAFT STILL THE GOLD STANDARD IN SPINAL FUSION SURGERY? A SURVEY OF SPINE SURGEONS: SP7. ... Is Iliac Crest Bone Graft Still the Gold Standard in Spinal Fusion Surgery? A Survey of Spine Surgeons: Paper #99 ... bone graft substitutes represent an acceptable alternative and that ICBG may no longer be the gold standard in spinal fusion ...
Patent US5697932 - Bone graft delivery system and method - Google Patents
A trial prosthesis is used to shape the bone graft within the canal for the prosthesis. Space for a cement mantle can be left ... The hollow tube is withdrawn from the medullary canal while the plunger is pushed into the canal, resulting in bone graft ... The hollow tube, bone graft and plunger assembly are inserted into the medullary canal which has been prepared for the assembly ... A surgical technique for the delivery of bone graft to a medullary canal and implantation of a prosthetic device includes ...
Spinal fusion - Mayo Clinic
Fusion. To fuse the vertebrae together permanently, the surgeon places the bone graft material between the vertebrae. Metal ... Your doctor may recommend spinal fusion to treat:. *Deformities of the spine. Spinal fusion can help correct spinal deformities ... Fusion from back of neck. Fusion from back of neck. When spinal fusion is performed from the back of the neck (posterior ... After spinal fusion. A hospital stay of two to three days is usually required following spinal fusion. Depending on the ...
Acrylic cages are good alternatives to bone graft and PEEK in anterior cervical discectomy and fusion - Spinal News...
Acrylic cages are good alternatives to bone graft and PEEK in anterior cervical discectomy and fusion. 24th March 2015. 223 ... Alex Vaccaro, incoming Editor-in-Chief of the Journal of Spinal Disorders and Techniques, told Spinal News International that " ... are as clinically effective as PEEK cages and bone graft in promoting fusion following an anterior cervical discectomy (ACDF). ... although there are many options for restoring physiologic disc height and enhancing spinal fusion, they believed that "the ...
SurgicalSpineScoliosisInstrumentationAutograftSubstitutes marketInterbodyStenosisSurgeriesSurgeonsScoliosisProcedureInfuse Bone GraftPosterior spinalVertebrae togetherTypes of boneSynthetic boneSubstituteAllograftsCordAllograft BoneReconstructionAutogenous boneFuseImplantsAnterior cervicalVertebralType of graftInfectionFilled with bone graftPreparing the bone graftInstabilitySurgeonFractureProceduresStabilize the spinePatientsCervical fusion2017IntervertebralCost of bone graftsAutologousLumbar spinal fusion
- Surgical Outcomes, Complications, and Long-Term Functionality for Free Vascularized Fibula Grafts in the Pediatric Population: A 17-Year Experience and Systematic Review of the Literature J Reconstr Microsurg. (usc.edu)
- Surgical technique for balancing posterior spinal fusions to the pelvis using the T square of Tolo J Pediatr Orthop. (usc.edu)
- Autograft is considered the gold standard of bone grafts because it contains the patient's bone cells, proteins, and calcified matrix, all of which help to stimulate healing of the fusion. (spineuniverse.com)
- The advantages of autograft include a greater chance for fusion success and negligible risk of disease transmission. (spineuniverse.com)
- Allograft bone does not contain living bone cells and therefore is not as effective at stimulating fusion compared to autograft bone. (spineuniverse.com)
- Autograft (your own bone) and allograft (donor bone) are 2 types your surgeon may use during spinal fusion surgery. (spineuniverse.com)
- Autograft and allograft are currently the most frequently used bone graft types for spinal fusion surgery, but new biomedical materials are advancing the case for bone graft substitutes. (spineuniverse.com)
- Real bone refers to bone graft coming from your own body (known as autograft or autogenous) or harvested from a cadaver donor (called allograft). (spineuniverse.com)
- Autograft bone graft is taken from your own body, most likely from your hip (really the pelvis), ribs, or leg. (spineuniverse.com)
- Local autograft comes from the vertebra itself and may be from removed bone spurs , lamina, or parts of the spinous process removed during fusion surgeries that remove bone to decompress pinched nerves. (spineuniverse.com)
- Autograft bone is the most popular type of bone graft because it has no risk of disease transmission, and your body accepts the transplant well because the bone is coming from your own body. (spineuniverse.com)
- While the benefits of autograft are numerous and hard for bone graft substitutes to replicate, there are some drawbacks. (spineuniverse.com)
- Clinical data compared patients who received Infuse Bone Graft versus autograft for lumbar fusion. (medtronic.com)
- Infuse Bone Graft results indicate it heals patients as well as autograft. (medtronic.com)
- Traditional lumbar fusion using autograft presents many limitations. (medtronic.com)
- To weigh autograft against Infuse Bone Graft used in conjunction with an LT-Cage™ device (at a single level), a prospective, randomized clinical trial compared the two. (medtronic.com)
- Infuse Bone Graft matched the ability of autograft to reduce pain and disability. (medtronic.com)
- Infuse Bone Graft eliminates hip pain and the complications related to autograft bone harvest. (medtronic.com)
- Both autograft and allograft bone graft have been reported to provide reasonable fusion rates in the anterior spinal column. (mitchmedical.us)
- The high rate of fusion obtained with autograft must be weighed against the morbidity of harvesting large sections of autogenous bone graft from the pelvis. (mitchmedical.us)
- A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and 'real world' use of approved and commercially available bone graft substitutes, autograft and allograft. (clinicaltrials.gov)
- Patients who undergo a planned spinal fusion procedure requiring approved bone grafting materials (e.g., bone grft substitutes, allograft or autograft). (clinicaltrials.gov)
- This type of graft is called an autograft. (aaos.org)
- Autograft is considered as the gold standard in bone grafting. (nih.gov)
- Due to the disadvantages of iliac crest bone and the poor bone quality of autograft gained from decompression surgery, alternative filling materials for posterior lumbar interbody fusion cages have been developed. (nih.gov)
- There are many types of spinal fusion and each technique involves using bone grafting -either from the patient ( autograft ), donor ( allograft ), or artificial bone substitutes-to help the bones heal together. (wikipedia.org)
- The purpose of this review was to compare the efficacy and safety of synthetic bone graft substitutes versus autograft or allograft for the treatment of lumbar and cervical spinal degenerative diseases. (thejns.org)
- Multiple major medical reference databases were searched for studies that evaluated spinal fusion using synthetic bone graft substitutes (either alone or with an autograft or allograft) compared with autograft and allograft. (thejns.org)
- The cells are then combined with another type of graft-such as local bone autograft, allograft, or synthetic bone-to speed the healing process. (orthoinfo.org)
- Decreasing the quantity of autograft significantly reduced the fusion rate. (lww.com)
- The data indicated that Augment products and the current standard of care, iliac crest autograft, are equivalent in this model of interbody spine fusion. (lww.com)
- An HS, Simpson JM, Glover JM, Stephany J (1995) Comparison between allograft plus demineralized bone matrix versus autograft in anterior cervical fusion. (springer.com)
- Barlocher CB, Barth A, Krauss JK, Binggeli R, Seiler RW (2002) Comparative evaluation of microdiscectomy only, autograft fusion, polymethylmethacrylate interposition, and threaded titanium cage fusion for treatment of single-level cervical disc disease: a prospective randomized study in 125 patients. (springer.com)
- Typically, the graft will include your bone shavings (autograft) and a synthetic BMP. (mayfieldclinic.com)
- This bone graft material will help in filling gaps in the skeletal system and can be used on its own or in combination with allograft or autograft. (medgadget.com)
- Based on type, it is segmented into bone morphogenetic protein, synthetic bone grafts, demineralized bone matrix, autograft and others. (medgadget.com)
- Albany - NY, Sept. 7, 2015 (GLOBE NEWSWIRE) -- According to a new market report published by Transparency Market Research Bone Grafts and Substitutes Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2015 - 2023 , the global bone grafts and substitutes market was valued at USD 2.35 billion in 2014 and is anticipated to expand at a CAGR of 4.5% from 2015 to 2023 to reach USD 3.48 billion in 2023. (cnbc.com)
- Factors such as rapid technological changes from autografts to allografts and penetration of synthetic and tissue engineered bone grafts in the market are propelling the growth of the bone grafts and substitutes market. (cnbc.com)
- Moreover, increasing demand from customers and rising industry standards are spurring the growth of the global bone grafts and substitutes market. (cnbc.com)
- Thus, these factors are expected to drive the global bone grafts and substitutes market during the forecast period from 2015 to 2023. (cnbc.com)
- Bone graft substitutes is the fastest growing segment of the global bone grafts and substitutes market. (cnbc.com)
- The market intelligence publication delves into the condition of the global Synthetic Bone Graft Substitutes market. (openpr.com)
- An in-depth examination of the existing market state, past progress, and forthcoming prospects of the global Synthetic Bone Graft Substitutes market has been presented in the research report. (openpr.com)
- The research publication also reports the chief strategies, key market shares, and product portfolio of the principal participants in work in the global Synthetic Bone Graft Substitutes market. (openpr.com)
- The study furthermore deals with the key geographical subdivisions of the global Synthetic Bone Graft Substitutes market and provides details about their previous and existing shares. (openpr.com)
- The trends leading in the global Synthetic Bone Graft Substitutes market have also been emphasized in the research report. (openpr.com)
- The global Synthetic Bone Graft Substitutes market has been methodically inspected with regards to the equivalent market segments and estimation period. (openpr.com)
- Each year within the distinct timeline has been briefly measured in terms of the value of the produce in the regional as well as global Synthetic Bone Graft Substitutes market. (openpr.com)
- To give a clear idea of the global Synthetic Bone Graft Substitutes market, the vendor landscape has been extensively gauged and also put into understanding along with the value chain analysis. (openpr.com)
- Among geographical regions, North America contributes the maximum share in the bone grafts and substitutes market, owing to the increasing research and development activities in the field of bone grafting, which results in development of innovative bone grafts in the region. (coherentmarketinsights.com)
- The global bone grafts and substitutes market was valued at US$ 2,640.1 million in 2016 and is expected to witness a robust CAGR of 5.5 % over the forecast period (2017 - 2025). (coherentmarketinsights.com)
- Fact.MR has announced the addition of the Injectable Bone Graft Substitutes Market Forecast, Trend Analysis & Competition Tracking - Global Review 2018 to 2028"report to their offering. (ukprwire.com)
- The global injectable bone graft substitutes market is segmented on the basis of type, application, and end users. (ukprwire.com)
- Geographically, the global injectable bone graft substitutes market is segmented into various regions such as North America, Latin America, Europe, Asia-Pacific excluding Japan (APEJ), Japan, and the Middle East and Africa (MEA). (ukprwire.com)
- North America is expected to represent a leading revenue contributor in the global Injectable Bone Graft Substitutes Market owing to increasing inclination of patients towards minimally invasive treatment procedure. (ukprwire.com)
- High geographical presence of leading players in the region is also driving the injectable bone graft substitutes market. (ukprwire.com)
- In addition, Europe is expected to account for the second large share in the global injectable bone graft substitutes market throughout the forecast period. (ukprwire.com)
- Market Research Future (MRFR)'s latest study reveals that the Global Bone Graft Substitutes Market is expected to expand at 6.52% CAGR during the forecast period 2017 to 2027. (medgadget.com)
- The factors that are responsible for dictating the growth trajectory of the bone graft substitutes market during the projection period are high demand in military medical units, increasing orthopedic problems, rising need for reconstructive orthopedic treatments, etc. (medgadget.com)
- Research and Markets has announced the addition of the 'Bone Grafts And Substitutes Market Analysis By Material, By Application Forecasts To 2024' report to their offering. (prnewswire.co.uk)
- The global bone graft and substitutes market is expected to reach over USD 3.6 billion by 2024, growing at an estimated CAGR of 5.2% from 2016 to 2024. (prnewswire.co.uk)
- The present invention is directed to methods of inserting a variety of interbody spinal fusion implants across a disc space between adjacent vertebral bodies. (google.ca)
- Synthetic materials are FDA-approved for anterior lumbar interbody fusion surgeries. (spine-health.com)
- The prospective, single-blind randomised controlled clinical study enrolled a total of 64 patients who were randomly allocated to undergo ACDF either with acrylic interbody fusion cage filled with bone substitute (n=32) or PEEK cage (n=32). (spinalnewsinternational.com)
- An artificial interbody spinal implant adapted for placement across an intervertebral space formed across the height of a disc space between two adjacent vertebral bodies is disclosed. (google.es)
- 2. The method of claim 1 , wherein the providing the pair of interbody spinal implants includes providing the pair of implants where the junction of the exterior facing side wall and the leading end of each implant is adapted so as not to substantially extend beyond the outer dimensions of the vertebral bodies when inserted within the implantation space. (google.es)
- 5. The method of claim 3 , wherein the providing the pair of interbody spinal implants includes providing the implant with the first distance being less than the third distance. (google.es)
- An improved method for anterior interbody fusion to form a fused bone segment having a predetermined. (google.com.au)
- Interbody cage fusion uses a hollow threaded titanium or carbon fiber cylinder to fuse two vertebrae together. (medlineplus.gov)
- Both patients underwent successful removal of the implant and revision to titanium posterior spinal fusion and interbody fusion without further complication. (thejns.org)
- University of Maryland Spine Center: "A Patient's Guide to Anterior Lumbar Interbody Fusion. (webmd.com)
- The results of anterior interbody fusion of the cervical spine. (springer.com)
- Anterior interbody lumbar spine fusion, analysis of Mayo Clinic Series. (springer.com)
- did C4-5 interbody fusion for cervical stenosis. (medhelp.org)
- The objective of the study was to determine interbody spine fusion with Augment Bone Graft and Augment Injectable Bone Graft implanted within a polyetheretherketone spacer. (lww.com)
- I had posterior interbody fusion (bars and screws etc. (healthboards.com)
- Bishop RC, Moore KA, Hadley MN (1996) Anterior cervical interbody fusion using autogeneic and allogeneic bone graft substrate: a prospective comparative analysis. (springer.com)
- Boden SD, Zdeblick TA, Sandhu HS, Heim SE (2000) The use of rhBMP-2 in interbody fusion cages. (springer.com)
- Boker DK, Schultheiss R, Probst EM (1989) Radiologic long-term results after cervical vertebral interbody fusion with polymethyl methacrylat (PMMA). (springer.com)
- Based on product, the market is segmented into thoracolumbar devices, cervical fusion devices, and interbody fusion devices. (openpr.com)
- However, the interbody fusion devices segment is projected to manifest the fastest CAGR of 3.6% during the forecast period. (openpr.com)
- The interbody fusion devices segment is further divided into non-bone interbody fusion devices and bone interbody fusion devices. (openpr.com)
- The non-bone interbody fusion devices segment held more than two-thirds of the total market share in 2015. (openpr.com)
- AxiaLIF stands for axial lumbar interbody fusion . (mayfieldclinic.com)
- In November 2018, Bio2 Technologies, an orthopedic company, has received approval from FDA for evaluation of its Vitrium bioactive glass as a cervical interbody fusion device. (medgadget.com)
- A cervical spinal fusion is also used as a follow-up treatment for spinal stenosis, disc hernia, rheumatoid arthritis, and other types of spinal deformities. (medicalhealthtests.com)
- Other common pathological conditions that are treated by spinal fusion include spinal stenosis , spondylolisthesis , spondylosis , spinal fractures , scoliosis , and kyphosis . (wikipedia.org)
- The greatest benefit appears to be in spondylolisthesis , while evidence is less good for spinal stenosis . (wikipedia.org)
- Other common causes include disc herniation, spinal stenosis, trauma, and spinal tumors. (wikipedia.org)
- Spinal stenosis results from bony growths ( osteophytes ) or thickened ligaments that cause narrowing of the spinal canal over time. (wikipedia.org)
- As a follow-up procedure to treat spinal stenosis , a herniated disc , the effects of rheumatoid arthritis , an infection, tumors, or spinal deformities. (healthwise.net)
- In Denmark the current surgical standard is the use of non-instrumented fusion in treating elderly patients with spinal stenosis and concomitant degenerative olisthesis. (medindia.net)
- Nonsurgical treatment does not relieve pain, and severe nerve compression symptoms of spinal stenosis (such as numbness or weakness) are getting worse. (cigna.com)
- However, bone graft substitutes are widely used and account for more than 2 million surgeries annually worldwide, according to a 2015 review of bone graft substitutes published in World Journal of Orthopedics . (spineuniverse.com)
- However, when your own bone quantity and/or quality are not enough alone to assist in these types of surgeries, other bone grafting options must be considered. (medtronic.com)
- Spinal fusion is one of the most common surgeries done in the neck or back. (orthoinfo.org)
- As the need to conduct trauma and orthopedic surgeries persist, manufacturers are developing a range of bone grafts or bone graft substitutes to stimulate insufficient or impaired bone regeneration. (ukprwire.com)
- Third, the tubular instruments do not cut through any back muscles like other fusion surgeries. (mayfieldclinic.com)
- How many spinal surgeries has my surgeon performed and has he or she had good results? (aaos.org)
- Utilization of BGS was observed to be the highest in spinal fusion surgeries among other applications. (prnewswire.co.uk)
- Increased demand for spinal fusion surgeries owing to the surging geriatric population coupled with the demand for minimally invasive surgeries is the foremost factor spurring the demand for BGS in spinal fusion surgeries. (prnewswire.co.uk)
- Spine surgeons can use bone graft to stop motion between two or more vertebral bodies, stabilize a corrected spinal deformity, or repair spinal fractures. (spineuniverse.com)
- There are several bone graft options available to surgeons and the choice of which to use is dependent on many factors. (cincinnatispinesurgeon.com)
- According to the American Academy of Orthopaedic Surgeons, the ideal bone graft substitute (BGS) is biocompatible, easy to use, osteoinductive, osteoconductive, structurally similar to bone, and cost effective. (cnbc.com)
- Some surgeons refuse to do elective bone grafting procedures on people who smoke. (healthline.com)
- This survey emphasizes the significance of donor site morbidity amongst spine surgeons when selecting bone graft material. (lww.com)
- Surgeons perform spinal fusion while you're under general anesthesia so you're unconscious during the procedure. (mayoclinic.org)
- Spine surgeons choose Acuity Surgical for spinal implant solutions. (spine.org)
- In spinal fusion procedures, surgeons use bone graft to join and stabilize vertebrae. (medindia.net)
- In a spinal fusion , surgeons weld together adjacent vertebrae with a bone graft. (scpr.org)
- Feb 2019- Sirakoss Ltd received CE mark clearance for its Osteo, the bone graft substitute which is nanosynthetic in nature intended to augment the healing of patients and offer surgeons with an advanced bone fracture solution. (medgadget.com)
- For a long time now, surgeons have used an approach called the anterior cervical discectomy and fusion (ACDF). (spineuniversity.com)
- According to the American Academy of Orthopaedic Surgeons, approximately a quarter-million spinal fusions are performed each year, half on the upper and half on the lower spine. (surgeryencyclopedia.com)
- Founded on the basis of combining quality engineering with surgeon innovation, the company provides surgeons with the highest quality medical devices for the treatment of complex orthopedic and neurological spinal disorders. (medindia.net)
- Because not all spinal surgeons treat scoliosis patients, it is important to ask your surgeon if treating scoliosis is an important part of his or her practice. (aaos.org)
- Many spinal conditions cause instability and/or pain (eg, degenerative disc disease, scoliosis , trauma) and require treatment with a spinal fusion. (spineuniverse.com)
- Patients with severe scoliosis or kyphosis also may need a fusion to correct the spinal deformity. (cincinnatispinesurgeon.com)
- Spinal fusion can help correct spinal deformities, such as a sideways curvature of the spine (scoliosis). (mayoclinic.org)
- Exclusion criteria were revisions, neuromuscular scoliosis, ankylosing spondylitis, and patients who had both BMP and ICBG used for fusion. (elsevier.com)
- The thoracic spine is more immobile, so most fusions are performed due to trauma or deformities like scoliosis and kyphosis . (wikipedia.org)
- The purpose of a spinal fusion (arthrodesis) procedure is to link or weld bones together. (spineuniverse.com)
- A bone graft harvesting procedure presents a separate set of surgical risks, including: post-operative pain, nerve injury, or surgical wound problems. (spineuniverse.com)
- The results also show that Infuse Bone Graft saved hospitals money by avoiding this secondary procedure. (medtronic.com)
- With an allograft, synthetic, or growth factors, patients can avoid the need to have bone harvested for a trauma procedure or spinal fusion. (medtronic.com)
- Spinal fusion is a surgical procedure used to join two or more vertebrae together. (cincinnatispinesurgeon.com)
- It is critical to quit smoking before any fusion procedure. (cincinnatispinesurgeon.com)
- To perform a cervical spinal fusion procedure, the surgeon will need to make an incision in the neck. (medicalhealthtests.com)
- Spinal fusion is a surgical procedure used to correct problems with the small bones in the spine (vertebrae). (aaos.org)
- This procedure involves removing bone and diseased tissues that are putting pressure on spinal nerves. (aaos.org)
- If you are having a decompression procedure, the surgeon may harvest your bone from the site of the decompression and use it as the graft. (aaos.org)
- A bone graft is a surgical procedure used to fix problems with bones or joints. (healthline.com)
- Spinal fusion is a procedure that permanently joins two vertebrae into one solid bone. (healthline.com)
- Spinal fusion is generally a safe procedure. (mayoclinic.org)
- Spinal fusion is a surgical procedure in which two or more vertebrae are permanently joined into one solid bone with no space between them. (healthline.com)
- A spinal fusion procedure may also include a discectomy. (healthline.com)
- Since each surgeon faces difficulties to select the most suitable bone graft or bone graft substitute for each trauma and orthopedic surgical procedure that requires bone grafting. (ukprwire.com)
- Anterior cervical discectomy with fusion is a common surgical procedure for patients suffering pain and/or neurological deficits and unresponsive to conservative management. (springer.com)
- Spinal fusion is not a common procedure. (medibank.com.au)
- A procedure to release pressure on the spinal cord and nerves that travel into the legs . (upmc.com)
- A procedure on the cervical spine to remove herniated disk material that is placing pressure on the nerves that travel into the arms or spinal cord . (upmc.com)
- Spinal fusion is a procedure that promotes the fusing, or growing together, of two or more vertebrae in the spine. (surgeryencyclopedia.com)
- There are a variety of specialized techniques that can be used in spinal fusion, although the basic procedure is the same. (cigna.com)
- If you have a spinal fusion, you'll get general anesthesia before the procedure. (kidshealth.org)
Infuse Bone Graft14
- 143 patients were treated with Infuse Bone Graft. (medtronic.com)
- The results indicated at 24 months, Infuse Bone Graft fusion rate was 94.5%, a higher percentage than the 88.7% fusion rate of the control group (though statistically equivalent). (medtronic.com)
- Compared to preoperative scores, Infuse bone graft patients indicated a 55% improvement on average. (medtronic.com)
- A statistically significant decrease was realized in blood loss among Infuse Bone Graft patients. (medtronic.com)
- The Medtronic Infuse Bone Graft has been linked to life-threatening complications in patients who were given Medtronic off-label . (lawyersandsettlements.com)
- Send your Medtronic Infuse Bone Graft claim to a lawyer who will review your claim at NO COST or obligation. (lawyersandsettlements.com)
- Lawyers for plaintiffs in the Medtronic Infuse Bone Graft litigation believe that injuries received from this product, dating back to as early as 2003, may still be able to file a claim. (lawyersandsettlements.com)
- The Medtronic Infuse Bone Graft is not approved for any other uses but it has been used off-label in cervical spine (neck) procedures. (lawyersandsettlements.com)
- In 2002 the FDA granted Medtronic approval for its Infuse Bone Graft, but for limited use in the lumbar spine, or lower back, and for some oral and dental procedures. (lawyersandsettlements.com)
- Specifically, the agency approved the Infuse Bone Graft to treat degenerative disc disease and open fractures on the tibia. (lawyersandsettlements.com)
- The FDA also approved Medtronic Infuse Bone Graft for use in sinus augmentation and localized alveolar ridge augmentation. (lawyersandsettlements.com)
- In the wake of at least 38 reports of complications, In July 2008, the FDA issued a warning concerning off-label Medtronic Infuse Bone Graft use, stating that risks were associated with the use of the bone graft on the cervical spine. (lawyersandsettlements.com)
- The Wall Street Journal also said that Medtronic paid approximately $800,000 over three years to a surgeon who was accused of fabricating a study that reported positive results for the Infuse Bone Graft. (lawyersandsettlements.com)
- Meanwhile, the FDA was reportedly concerned about Medtronic off-label use of the Infuse Bone Graft before the product was even approved, according to The Wall Street Journal . (lawyersandsettlements.com)
- Use of anterior and/or posterior spinal instrumentation can improve fusion rates when structural allograft bone grafts are used. (mitchmedical.us)
- A posterior spinal fusion is when an incision is made along the back. (chkd.org)
- Research has shown the early mobilization after a posterior spinal fusion provides a patient with the ability to get back to being a kid quickly. (chkd.org)
- Depending on whether your surgeon approaches your spine from the front (anterior spinal fusion) or from the back (posterior spinal fusion), the vertebrae will be fastened together either with a metal plate or with rods and screws. (mayoclinic.org)
- I had my posterior spinal fusion April 29, 2009. (healthboards.com)
- In simplest terms, the goal of a spinal fusion is to fuse 2 spinal bones (vertebrae) together, creating 1 solid bone and restoring spinal stability or restoring alignment. (spineuniverse.com)
- Called bone graft, this bone acts as the "cement" that fuses the vertebrae together. (va.gov)
- When spinal fusion is performed from the back of the neck (posterior cervical fusion), rods and screws are used to hold the vertebrae together. (mayoclinic.org)
- An apparatus and method for implanting an intervertebral cage containing a bone graft and fusing adjacent vertebrae together while maintaining or correcting the angular alignment and balance of the spine. (google.com.au)
- Additional hardware (screws, plates, or cages) is often used to hold the bones in place while the graft fuses the two vertebrae together. (wikipedia.org)
- These grafts will regenerate, grow into the bone, and fuse the vertebrae together. (medlineplus.gov)
Types of bone6
- This article will review the different types of bone graft available today. (spineuniverse.com)
- Below you can learn about the different types of bone grafts. (spineuniverse.com)
- In general, these types of bone graft are a synthetic or a manipulated type of a naturally-occurring product. (spine-health.com)
- The market is primarily segmented according to its applications, types of harvesting and fixation devices and the types of bone grafts. (marketresearch.com)
- Your surgeon will also explain the various types of bone graft. (mayfieldclinic.com)
- There are many types of bone graft used in spinal fusion. (aaos.org)
- The bone graft substitutes segment has been further classified into synthetic bone grafts, bone morphogenetic protein (BMP), and others. (cnbc.com)
- The bone graft substitutes segment comprises synthetic bone grafts, bone morphogenetic proteins (BMP), and others. (cnbc.com)
- This new report from Medtech Insight/Elsevier Business Intelligence provides market forecasts and analysis of the European market for bone graft substitute products including bone morphogenetic proteins, demineralized bone matrix, and synthetic bone graft substitutes. (lsintel.com)
- Synthetic Bone Graft Substitutes a. (lsintel.com)
- The research report provides an intrusive insight into the global market for Synthetic Bone Graft Substitutes based on principal parameters such as technology, end user, products, applications, and geographical segments. (openpr.com)
- The assessed volume and revenue progress of the global market for Synthetic Bone Graft Substitutes over the coming years has also been stated in the market intellect publication. (openpr.com)
- The US market for Bone Graft Substitutes is also analyzed by the following segments: Standard Allografts, Machined Bone Allografts, Demineralized Bone Matrix (DBM), Bone Morphogenetic Protein (BMP), Stem Cell Based Bone Grafts, and Synthetic Bone Grafts. (marketpublishers.com)
- The bone graft may also be a synthetic bone or an allograft, which is a bone from a bone bank. (healthline.com)
- Synthetic bone grafts are made from calcium materials and are often called "ceramics. (orthoinfo.org)
- The market growth is driven by unhealthy lifestyle choices leading to increasing degenerative joint diseases, various technological advancements in bone grafting techniques and the evolution of sophisticated biocompatible synthetic bone grafts. (marketresearch.com)
- Dr. Hyun Bae, MD, Chief Medical Officer of Prosidyan, commented, "With FIBERGRAFT we now finally have the next generation of synthetic bone grafting for spine. (pr.com)
- Synthetic bone grafts have been stagnant for twenty years using the same porous technology. (pr.com)
- FIBERGRAFT is the exclusive synthetic bone graft which uses bioactive glass fibers to provide direct connectivity. (pr.com)
- This is a paradigm shift in synthetic bone grafting. (pr.com)
- There are very few synthetic bone grafts with FDA clearance for postero-lateral spinal fusion. (pr.com)
- Prosidyan's flagship product, FIBERGRAFT BG Morsels, a synthetic bone graft substitute, has been in the market for over 18 months. (pr.com)
- About Prosidyan: Prosidyan is the creator and supplier of the next generation in synthetic bone grafting through its proprietary manufacturing process utilizing microscopic fibers of bioactive glass. (pr.com)
- What is a Bone Graft Substitute? (spineuniverse.com)
- The European market for bone graft substitute products for spinal fusion is projected to experience significant growth over the next half-decade due to a number of factors, particularly an increased prevalence of degenerative disc disease. (lsintel.com)
- Human perivascular stem cell-based bone graft substitute induces rat spinal fusion. (ed.ac.uk)
- I asked a doctor on our Board to weigh in, and he offered a third choice: Consider using a bone graft substitute instead. (spine-health.com)
- In his years of experience as a doctor, using a bone graft substitute along with a titanium cage has allowed this surgeon to avoid subjecting his patients to potentially painful bone graft harvests or to other people's tissues (as in cadaver bone), and this type of graft has become his preference. (spine-health.com)
- The Europe Bone Graft Substitute for Spinal Fusion market size is $XX million USD in 2018 with XX CAGR from 2014 to 2018, and it is expected to reach $XX million USD by the end of 2024 with a CAGR of XX% from 2019 to 2024. (globalindustrymagazine.com)
- This report is an essential reference for who looks for detailed information on Europe Bone Graft Substitute for Spinal Fusion market. (globalindustrymagazine.com)
- In addition to the data part, the report also provides overview of Bone Graft Substitute for Spinal Fusion market, including classification, application, manufacturing technology, industry chain analysis and latest market dynamics. (globalindustrymagazine.com)
- There are several substances such as ceramics, calcium phosphates and other synthetic materials that have similar biomechanical properties and structure similar to that of cadaver bone and may be used as a bone graft substitute. (spine-health.com)
- The North America bone graft and substitute market is forecasted to rise at a CAGR of 5.39% over the projected period of 2018-2026. (marketresearch.com)
- Therefore, bone graft or bone graft substitute should have the properties such as the biocompatibility, osteoconductive, osteoinductive, and osteogenic properties, as well as the biomaterial should provide sufficient mechanical support to allow for an optimal biomechanical environment in which bone regeneration occur. (ukprwire.com)
- The global market for injectable bone graft substitute is segmented in terms of type, applications, and end users. (ukprwire.com)
- For example, arthroscopically assisted treatment with percutaneous internal fixation with injectable bone graft substitute is one of the reliable and minimally invasive methods to achieve union and scaphoid healing. (ukprwire.com)
- FIBERGRAFT BG Morsels is an ultra-porous Bone Graft Substitute, made entirely from 45S5 Bioactive Glass microfibers and microspheres, engineered for optimal biological response. (pr.com)
- FIBERGRAFT BG Morsels - Bone Graft Substitute is indicated only for bony voids or gaps that are not intrinsic to the stability of the bony structure. (pr.com)
- i-FACTOR Peptide Enhanced Bone Graft is a bone graft substitute material for use in the repair of bony voids or defects in orthopedic applications throughout the skeletal system (i.e., the spine and extremities). (medindia.net)
- The Global Bone Graft Substitute Market is expected to touch USD 5,031 million at a stellar 6.52% CAGR over the forecast period (2017-2027). (medgadget.com)
- In September 2018, Baxter International Inc., an American healthcare company, announced the receipt of FDA clearance for Actifuse Flow bone graft substitute to be used in orthopedic surgical procedures. (medgadget.com)
- Market Research Future report offers an all-inclusive segmental analysis of the bone graft substitute market on the basis type and application. (medgadget.com)
- Based on application, the bone graft substitute market is segmented into foot and ankle, dental, long bone, joint reconstruction, spinal fusion and others. (medgadget.com)
- Based on region, the bone graft substitute market covers growth opportunities and latest trends across North America, Europe, Asia Pacific and Middle East and Africa. (medgadget.com)
- US has a highly developed healthcare sector which is another key reason that is driving the bone graft substitute market in this region. (medgadget.com)
- Today, human bone autografts and allografts are the most common bone graft options for spinal fusion patients. (spineuniverse.com)
- The global bone grafts and substitutes (BGS) market has been categorized into allografts and bone graft substitutes. (cnbc.com)
- In the U.S., approximately one third of bone graft procedures use allografts, however risk of infection transmission is associated with its usage. (cnbc.com)
- Processed allografts represented 90% of all grafts used. (nih.gov)
- Autografting is now limited to revision operations after failed fusions, and to combined use at the junction with massive allografts. (nih.gov)
- Balabhadra RSV, Kim DH, Zhang H (2004) Anterior cervical fusion using dense cancellous allografts and dynamic plating. (springer.com)
- However, there are certain restraints in the market, which include the risk of disease transmission in allografts and xenograft, improper fixation and weak bonding, and risk of graft rejection. (medgadget.com)
- Continual efforts to develop improved allografts such as demineralized bone matrix grafts with greater osteoconductive and osteoinductive capabilities are anticipated to have a positive impact on the growth of the segment during the forecast period. (prnewswire.co.uk)
- Re: Spinal cord stimulation. (drugs.com)
- What is spinal cord monitoring? (chkd.org)
- These electrodes monitor the brain's ability to send and receive messages from the spinal cord and nerves. (chkd.org)
- Injury to the spinal cord or nerves. (medicalhealthtests.com)
- All dogs had evidence of dynamic soft tissue spinal cord compression, as indicated by flexion, extension, and traction myelographic views. (osti.gov)
- Pressure on the nerves as they exit the spinal cord ( radiculopathy ) causes pain in the area where the nerves originated (leg for lumbar pathology, arm for cervical pathology). (wikipedia.org)
- After an injury, to stabilize the neck and prevent a bone fracture from causing instability or damage to the spinal cord , which may result in paralysis . (healthwise.net)
- Nerve or spinal cord injury. (healthwise.net)
- Because this area is usually filled with fat, this presacral path to the disc can be made without disturbing the spinal cord and nerves. (mayfieldclinic.com)
- Anterior fusion is performed through the front of the spine to avoid the spinal cord and spinal nerves. (spineuniversity.com)
- While the shapes of individual vertebrae differ among these regions, each is essentially a short hollow tube containing the bundle of nerves known as the spinal cord. (surgeryencyclopedia.com)
- Individual nerves, such as those carrying messages to the arms or legs, enter and exit the spinal cord through gaps between vertebrae. (surgeryencyclopedia.com)
- The bulge can press against nerves located in the spinal cord or exiting from it, causing pain. (surgeryencyclopedia.com)
- Certain types of curvatures are associated with problems related to the spinal cord. (aaos.org)
- Processing of allograft bone (cadaver bone graft) can be manipulated (demineralized) to extract the proteins that stimulate bone formation. (spine-health.com)
- Should I have allograft bone used for my fusion or my own bone harvested? (aaos.org)
- Allograft bone is often mixed with the patient's own marrow blood to improve its bone fusion capability. (aaos.org)
- Fusion was assessed using radiograph and CT scans with sagittal and coronal reconstruction. (medtronic.com)
- Factors such as increasing procedural volume of spinal fusion and joint reconstruction due to rising geriatric population and launch of innovative products are the major factors supporting the growth of this segment. (cnbc.com)
- Bone grafts and substitutes are used in various application areas such as spinal fusion, foot and ankle, long bone, dental, joint reconstruction, and craniomaxillofacial procedures. (cnbc.com)
- Simply put, bone graft is an implantable material that helps in promoting bone healing, osseous reconstruction and bone formation owing to its osteoinductive, osteogenic and osteoconductive properties. (medgadget.com)
- DBM is usually considered a bone graft extender rather than a replacement because its ability to fuse the human spine alone is not proven. (spineuniverse.com)
- Bone grafting is used to help fuse the spine in the correct position. (chkd.org)
- Your surgeon will prepare the bone graft that will be used to fuse the two vertebrae. (healthline.com)
- After 3 to 6 months, the bone graft should fuse the two vertebrae, forming one solid piece of bone. (mayfieldclinic.com)
- A key point to remember is that these implants are only a supplement to aid the fusion process. (cincinnatispinesurgeon.com)
- Spinal Fusion with Implants: Bone Graft or Prosthetic? (mfrlawoffice.com)
- Failure of the fusion, breakage of metal implants (if used), or both. (healthwise.net)
- Anderson DG, Albert TJ (2002) Bone grafting, implants, and plating options for anterior cervical fusions. (springer.com)
- If this incision is made in the front of the neck, it is called as an anterior cervical spine fusion, and if it is made on the back of the neck, it is called as a posterior cervical spine fusion. (medicalhealthtests.com)
- Believe ICBG should no longer be the gold standard in anterior cervical fusions: SRS 58%, 56% CSRS (p=0.67, no significant difference between conferences). (lww.com)
- A study published ahead-of-print by the Journal of Spinal Disorders and Techniques suggests that novel acrylic cages, composed of polymethylmethacrylate (PMMA) and methacrylate, are as clinically effective as PEEK cages and bone graft in promoting fusion following an anterior cervical discectomy (ACDF). (spinalnewsinternational.com)
- Bone morphogenetic protein (rhBMP) should not be routinely used in any type of anterior cervical spine fusion, such as with anterior cervical discectomy and fusion . (wikipedia.org)
- A report of seventeen cases treated by Robinson anterior cervical discectomy and fusion. (springer.com)
- Anterior cervical fusion for degenerated or protruded discs. (springer.com)
- White AA, Southwick WO, DePonte RJ, Gainer JW, Hardy R. Relief of pain by anterior cervical fusion for spondylosis. (springer.com)
- Agrillo U, Mastronardi L, Puzzilli F (2002) Anterior cervical fusion with carbon fiber cage containing coralline hydroxyapatite: preliminary observations in 45 consecutive cases of soft-disc herniation. (springer.com)
- Angevine PD, Zivin JG, McCormick PC (2005) Cost-effectiveness of single-level anterior cervical discectomy and fusion for cervical spondylosis. (springer.com)
- Baskin DS, Ryan P, Sonntag V, Westmark R, Widmayer MA (2003) A prospective, randomized, controlled cervical fusion study using recombinant human bone morphogenetic protein-2 with the CORNERSTONE-SR allograft ring and the ATLANTIS anterior cervical plate. (springer.com)
- Boakye M, Mummaneni PV, Garrett M, Rodts G, Haid R (2005) Anterior cervical discectomy and fusion involving a polyetheretherketone spacer and bone morphogenetic protein. (springer.com)
- In the United States , i-FACTOR Peptide Enhanced Bone Graft was approved via a PMA in 2015 only for use in single level anterior cervical fusion procedures. (medindia.net)
- inserting into said bore said spinal implant having opposed arcuate portions in an angular relationship to one another along the length of said implant and oriented toward the adjacent vertebral bodies. (google.ca)
- 7. The method of claim 1 , wherein the distracting step includes the step of inserting a spinal distractor into the disc space between the adjacent vertebral bodies. (google.ca)
- 8. The method of claim 7 , further comprising the step of positioning a sleeve over said spinal distractor and into contact with the adjacent vertebral bodies. (google.ca)
- Fusion limits motion at the fused vertebral segments, whereas disc replacement tries to keep as much of the natural motion as possible. (spineuniversity.com)
Type of graft3
Filled with bone graft2
Preparing the bone graft1
- Spinal weakness or instability. (mayoclinic.org)
- This patient population presents a challenging environment to obtain fusion due to their mechanical instability and biology," said Dr. Andersen. (medindia.net)
- I was so desperate after almost three weeks that I found a neurosurgeon and orthopedist who said, 'You have spinal instability. (scpr.org)
- This may be done to improve posture, increase ability to ventilate the lungs, prevent pain, or treat spinal instability and reduce the risk of nerve damage. (surgeryencyclopedia.com)
- Sometimes, because of these disadvantages and the possibility the patient has poor quality bone, the surgeon decides to use another type of bone graft. (spineuniverse.com)
- To stimulate the bone fusion, a spine surgeon will use additional bone called bone graft . (spineuniverse.com)
- Your surgeon will decide whether it is a better choice for your fusion. (va.gov)
- Your surgeon will make an incision in the skin above where the graft is needed. (healthline.com)
- Once the graft is securely in place, your surgeon will close the incision or wound with stitches and bandage the wound. (healthline.com)
- During spinal fusion, your surgeon places bone or a bonelike material within the space between two spinal vertebrae. (mayoclinic.org)
- If you decide to proceed with spinal fusion, ask your surgeon what approach would be best for you. (mayoclinic.org)
- The technique your surgeon uses depends on the location of the vertebrae to be fused, the reason for the spinal fusion, and in some instances, your general health and body shape. (mayoclinic.org)
- If you're having a cervical fusion, your surgeon will often make a small incision in the horizontal fold of the front of your neck to expose the cervical spine. (healthline.com)
- If you are a candidate for spinal fusion, the surgeon will explain your options. (mayfieldclinic.com)
- The surgeon will choose what type of bone graft material to use. (spineuniversity.com)
- After the first year, you should consult with your surgeon and physical therapist to determine if the graft is strong enough to withstand chiropractic manipulation. (livestrong.com)
- The exact type of bone graft used will depend on many factors, the most important of which is surgeon preference and experience. (aaos.org)
- Bone grafting is majorly performed in cases of sinus lift, ridge augmentation, fracture repair, nerve repositioning, and dental implantation. (coherentmarketinsights.com)
- Bone grafting processes such as allogenic, autologous and synthetic substrates are contributing to modern fracture care and bone loss treatments in this region. (marketresearch.com)
- Bone graft is also used to heal wounds, treat complex fracture and others. (medgadget.com)
- According to a report by the Agency for Healthcare Research and Quality (AHRQ) , approximately 488,000 spinal fusions were performed during U.S. hospital stays in 2011 (a rate of 15.7 stays per 10,000 population), which accounted for 3.1% of all operating room procedures. (wikipedia.org)
- In some spinal fusion procedures, parts of the spinal bones are removed to relieve pressure on the nerve roots. (orthoinfo.org)
- On the basis of application, the spinal fusion segment held the largest revenue share in 2019 owing to the growing number of spinal fusion procedures and new product approvals for the same. (yahoo.com)
- The potential ability of bone grafting to repair the damage using natural mechanism can thus, be helpful and incorporated for bone healing procedures. (coherentmarketinsights.com)
- Preference for minimally invasive treatment procedures has encouraged manufacturers to develop injectable bone graft substitutes globally. (ukprwire.com)
- Since, minimally invasive treatment procedures reduces the duration of hospital stay and offers rapid wound healing benefits, which creates the high demand for the injectable bone graft substitutes. (ukprwire.com)
- Rise in geriatric population, increase in prevalence of spinal disorders, and shift toward invasive spine procedures are the major drivers of the global spinal fusion devices market. (openpr.com)
- This data from the IVANOS study is another significant milestone as we advance on our commitment to increase the level of clinical evidence evaluating our P-15 technology, and we are proud to be leading the effort to address the evidence gap around commercial bone grafts often used in spinal fusion procedures," said Glen Kashuba , chief executive officer of Cerapedics. (medindia.net)
Stabilize the spine5
- Bone graft can either be structural (it supports the spine, typically in place of a disc or bone that was removed) or onlay, meaning it is a mass of bone fragments that grow together to stabilize the spine and bridge the joint. (spineuniverse.com)
- Bone grafts encourage bone formation to stabilize the spine and achieve the spinal fusion. (medtronic.com)
- Spinal fusion may be used to stabilize the spine after removal of a damaged (herniated) disk. (mayoclinic.org)
- In general, spinal fusion is performed to decompress and stabilize the spine. (wikipedia.org)
- In some cases, spinal fusion will be done at the same time to stabilize the spine. (cigna.com)
- Patients with fractures in the spine (as a result of a car accident or falls from heights) also may need a spinal fusion. (cincinnatispinesurgeon.com)
- Our Anterior spinal fusion patients length or stay can also be unique to each patient. (chkd.org)
- Patients are well served to educate themselves on their bone graft choices and be part of the process of deciding about which bone graft option will be used in their body. (spine-health.com)
- Farrokhi et al write that "Clinical improvement, disk spacing height, intervertebral angle and fusion rate in the patients of the acrylic cage group was better than the PEEK cage group. (spinalnewsinternational.com)
- All 32 patients in the ICBG had A/P fusion. (elsevier.com)
- With the advent of new adjunctive therapy, the overall survival of patients harboring spinal column tumors has improved. (thejns.org)
- The mean time to fusion was 5.4 ± 1.4 months (range 3-9 months), whereas 16 of 272 patients died before the confirmation of solid fusion with a mean survival of 3.1 ± 2.1 months (range 0.5-6 months). (thejns.org)
- The Wall Street Journal (09/08/08) reported that FDA records showed approximately 200 adverse events where patients experienced serious complications after the bone graft was used off-label. (lawyersandsettlements.com)
- Patients with 1-level DS achieved estimated fusion rates of 40 percent (29/72) with i-FACTOR Peptide Enhanced Bone Graft versus 21 percent (17/80) with allograft. (medindia.net)
- Patients with 2-level DS achieved estimated fusion rates of 63 percent (34/54) with i-FACTOR Peptide Enhanced Bone Graft versus 18 percent (6/34) with allograft. (medindia.net)
- While spine fusion generally helps to eliminate certain types of pain, it has also been shown to decrease function by limiting the range of motion for patients in flexion, extension, rotation and lateral bending. (google.com)
- Spinal fusion is indicated in patients whose curves are more severe or are progressing rapidly. (surgeryencyclopedia.com)
- During that time, patients should avoid movements that bend, twist or put strain on the spinal bones and risk breaking the graft. (livestrong.com)
- A case report published in the 2009 'Journal of the Academy of Chiropractic Orthopedists' said that patients who experience continued pain after lumbar fusion responded well to a combination of spinal adjustment and distraction decompression. (livestrong.com)
- Adam Tanase, D.C., a St. Louis-area chiropractor, advises that while chiropractors should not use rotational methods, or "twist-and-pop," that fusion patients could benefit from other spinal manipulation techniques. (livestrong.com)
- Fusion patients could be at greater risk for injury, especially if the graft is not strong enough or if the chiropractor is not familiar with non-rotational methods for spinal manipulation. (livestrong.com)
- This is called an anterior approach and requires an incision in the lower abdomen for a lumbar fusion or in the front of the neck for a cervical fusion. (aaos.org)
- Radiographic evidence of bony cervical fusion was observed during a 9- to 24-week period in 6 of the 8 surviving dogs. (osti.gov)
- The overall quality of evidence evaluating the potential use and superiority of the synthetic biological materials for lumbar and cervical fusion in this systematic review was low or insufficient, largely due to the high potential for bias and small sample sizes. (thejns.org)
- When spinal fusion is performed in the cervical spine along with a discectomy, it's called cervical fusion. (healthline.com)
- For instance, Artoss, Inc., a U.S.- based company introduced a complete line of bone grafts in 2017, which incorporates use of nanotechnology in the production of these grafts. (coherentmarketinsights.com)
- For instance, in May 2017, the National Chemical Laboratory in India, developed two novel bone graft substitutes that are aimed towards augmenting and regenerating the bones that are lost during accident or injuries. (coherentmarketinsights.com)
- A description of a technique and evaluation of results in anterior spinal fusion for deranged intervertebral disc and spondylolisthesis. (springer.com)
- BOCA RATON, Fla., Aug. 19 The NEWTON(TM) Intervertebral Body Spacer System is comprised of a complete line of lumbar spinal spacers that allow anterior, posterior or lateral insertion angles to reach the intervertebral disc space. (medindia.net)
- Through the use of a minimal-exposure patent-pending tube system, the NEWTON(TM) devices are implanted into the intervertebral space to provide stabilization and facilitate fusion. (medindia.net)
Cost of bone grafts1
- In fact, arthrodesis of the spine has become the most common reason for autologous bone graft harvest. (healio.com)
- 3 Because of these properties, autologous bone grafting has become the most commonly used source of graft and is the gold standard for most spinal fusion applications. (healio.com)
- Many of them are autologous , where a piece of bone is taken from the person who is getting the bone graft (auto = self). (spineuniversity.com)