Obstruction of flow in biological or prosthetic vascular grafts.
The degree to which BLOOD VESSELS are not blocked or obstructed.
The vein which drains the foot and leg.
Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.
The vessels carrying blood away from the capillary beds.
The removal of a limb or other appendage or outgrowth of the body. (Dorland, 28th ed)
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.
Surgical insertion of BLOOD VESSEL PROSTHESES, or transplanted BLOOD VESSELS, or other biological material to repair injured or diseased blood vessels.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
The main artery of the thigh, a continuation of the external iliac artery.
Operative procedures for the treatment of vascular disorders.
The inferior part of the lower extremity between the KNEE and the ANKLE.
The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and foot. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
The tunnel in the lower anterior ABDOMINAL WALL through which the SPERMATIC CORD, in the male; ROUND LIGAMENT, in the female; nerves; and vessels pass. Its internal end is at the deep inguinal ring and its external end is at the superficial inguinal ring.
The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.
The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
A complication of INTERNAL MAMMARY-CORONARY ARTERY ANASTOMOSIS whereby an occlusion or stenosis of the proximal SUBCLAVIAN ARTERY causes a reversal of the blood flow away from the CORONARY CIRCULATION, through the grafted INTERNAL MAMMARY ARTERY (internal thoracic artery), and back to the distal subclavian distribution.
Elements of limited time intervals, contributing to particular results or situations.
An alternative to amputation in patients with neoplasms, ischemia, fractures, and other limb-threatening conditions. Generally, sophisticated surgical procedures such as vascular surgery and reconstruction are used to salvage diseased limbs.
Use of a balloon CATHETER to block the flow of blood through an artery or vein.
Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.
Formation and development of a thrombus or blood clot in the blood vessel.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye.
Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.
A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
The relationship of all the components of the masticatory system in normal function. It has special reference to the position and contact of the maxillary and mandibular teeth for the highest efficiency during the excursive movements of the jaw that are essential for mastication. (From Jablonski, Dictionary of Dentistry, 1992, p556, p472)
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.
System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.
The vessels carrying blood away from the heart.
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
Agents that prevent clotting.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)
The act of constricting.
The transference of a kidney from one human or animal to another.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
Contact between opposing teeth during a person's habitual bite.
Methods used to temporarily or permanently block the flow of BODY FLUIDS through various ducts and tubules throughout the body, including BLOOD VESSELS and LYMPHATIC VESSELS such as by THERAPEUTIC EMBOLIZATION or LIGATION.
The condition of an anatomical structure's being constricted beyond normal dimensions.
Radiography of the vascular system of the brain after injection of a contrast medium.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
The arterial blood vessels supplying the CEREBRUM.
Radiography of blood vessels after injection of a contrast medium.
A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
Pathological conditions of intracranial ARTERIES supplying the CEREBRUM. These diseases often are due to abnormalities or pathological processes in the ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; and POSTERIOR CEREBRAL ARTERY.
The circulation of blood through the BLOOD VESSELS of the BRAIN.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Restoration of blood supply to tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. It is primarily a procedure for treating infarction or other ischemia, by enabling viable ischemic tissue to recover, thus limiting further necrosis. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing REPERFUSION INJURY.
The transference of a part of or an entire liver from one human or animal to another.
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)
Organs, tissues, or cells taken from the body for grafting into another area of the same body or into another individual.
The plan and delineation of prostheses in general or a specific prosthesis.
Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.
The flow of BLOOD through or around an organ or region of the body.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.
The circulation of blood through the CORONARY VESSELS of the HEART.
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The veins and arteries of the HEART.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Dental occlusion in which the occlusal contact of the teeth on the working side of the jaw is accompanied by the harmonious contact of the teeth on the opposite (balancing) side. (From Jablonski, Dictionary of Dentistry, 1992, p556)
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Localized or diffuse reduction in blood flow through the vertebrobasilar arterial system, which supplies the BRAIN STEM; CEREBELLUM; OCCIPITAL LOBE; medial TEMPORAL LOBE; and THALAMUS. Characteristic clinical features include SYNCOPE; lightheadedness; visual disturbances; and VERTIGO. BRAIN STEM INFARCTIONS or other BRAIN INFARCTION may be associated.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Application of a ligature to tie a vessel or strangulate a part.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Non-cadaveric providers of organs for transplant to related or non-related recipients.
An occlusion resulting in overstrain and injury to teeth, periodontal tissue, or other oral structures.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Disease having a short and relatively severe course.
The return of a sign, symptom, or disease after a remission.
Transplantation of an individual's own tissue from one site to another site.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Central retinal vein and its tributaries. It runs a short course within the optic nerve and then leaves and empties into the superior ophthalmic vein or cavernous sinus.
Transplantation of tissue typical of one area to a different recipient site. The tissue may be autologous, heterologous, or homologous.
The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.
An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).
A dead body, usually a human body.
Procedures used to reconstruct, restore, or improve defective, damaged, or missing structures.
The procedure of removing TISSUES, organs, or specimens from DONORS for reuse, such as TRANSPLANTATION.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
The transference of a heart from one human or animal to another.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Transference of fetal tissue between individuals of the same species or between individuals of different species.
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
Methods of creating machines and devices.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.
The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
Material, usually gauze or absorbent cotton, used to cover and protect wounds, to seal them from contact with air or bacteria. (From Dorland, 27th ed)
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Pathological processes involving any part of the AORTA.
The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.
Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Branch of the common carotid artery which supplies the exterior of the head, the face, and the greater part of the neck.
The induction of prolonged survival and growth of allografts of either tumors or normal tissues which would ordinarily be rejected. It may be induced passively by introducing graft-specific antibodies from previously immunized donors, which bind to the graft's surface antigens, masking them from recognition by T-cells; or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.
Part of the arm in humans and primates extending from the ELBOW to the WRIST.
The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
The continuation of the subclavian artery; it distributes over the upper limb, axilla, chest and shoulder.
A technique in which tissue is rendered resistant to the deleterious effects of prolonged ISCHEMIA and REPERFUSION by prior exposure to brief, repeated periods of vascular occlusion. (Am J Physiol 1995 May;268(5 Pt 2):H2063-7, Abstract)
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
Partial or total replacement of all layers of a central portion of the cornea.
Exposure of myocardial tissue to brief, repeated periods of vascular occlusion in order to render the myocardium resistant to the deleterious effects of ISCHEMIA or REPERFUSION. The period of pre-exposure and the number of times the tissue is exposed to ischemia and reperfusion vary, the average being 3 to 5 minutes.
The transference of pancreatic islets within an individual, between individuals of the same species, or between individuals of different species.
A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.
Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.
Delivery of drugs into an artery.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
An immunological attack mounted by a graft against the host because of tissue incompatibility when immunologically competent cells are transplanted to an immunologically incompetent host; the resulting clinical picture is that of GRAFT VS HOST DISEASE.
Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.
Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains.
A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.
A general term for the complex phenomena involved in allo- and xenograft rejection by a host and graft vs host reaction. Although the reactions involved in transplantation immunology are primarily thymus-dependent phenomena of cellular immunity, humoral factors also play a part in late rejection.
Recording of change in the size of a part as modified by the circulation in it.
The inferior and superior venae cavae.
Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
The largest of three bones that make up each half of the pelvic girdle.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
Veins which drain the liver.
Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY.
A subfamily of the Muridae consisting of several genera including Gerbillus, Rhombomys, Tatera, Meriones, and Psammomys.
Transference of brain tissue, either from a fetus or from a born individual, between individuals of the same species or between individuals of different species.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles, mammary gland and the axillary aspect of the chest wall.
Surgical removal of an obstructing clot or foreign material which has been transported from a distant vessel by the bloodstream. Removal of a clot at its original site is called THROMBECTOMY.
Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.
A polygonal anastomosis at the base of the brain formed by the internal carotid (CAROTID ARTERY, INTERNAL), proximal parts of the anterior, middle, and posterior cerebral arteries (ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; POSTERIOR CEREBRAL ARTERY), the anterior communicating artery and the posterior communicating arteries.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)
Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.
Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.

Detection of Chlamydia pneumoniae but not cytomegalovirus in occluded saphenous vein coronary artery bypass grafts. (1/1270)

BACKGROUND: A causal relation between atherosclerosis and chronic infection with Chlamydia pneumoniae and/or cytomegalovirus (CMV) has been suggested. Whether the unresolved problem of venous coronary artery bypass graft occlusion is related to infection with C pneumoniae and/or CMV has not been addressed. METHODS AND RESUTLS: Thirty-eight occluded coronary artery vein grafts and 20 native saphenous veins were examined. Detection of C pneumoniae DNA was performed by use of nested polymerase chain reaction (PCR). Homogenisates from the specimen were cultured for identification of viable C pneumoniae. Both conventional PCR and quantitative PCR for detection of CMV DNA were applied. Differential pathological changes (degree of inflammation, smooth muscle cell proliferation [MIB-1]) were determined and correlated to the detection of both microorganisms. C pneumoniae DNA could be detected in 25% of occluded vein grafts. Viable C pneumoniae was recovered from 16% of occluded vein grafts. Except for 1 native saphenous vein, all control vessels were negative for both C pneumoniae detection and culture. All pathological and control specimens were negative for CMV DNA detection. Pathological changes did not correlate with C pneumoniae detection. CONCLUSIONS: Occluded aorto-coronary venous grafts harbor C pneumoniae but not CMV. The detection of C pneumoniae in occluded vein grafts warrants further investigation.  (+info)

Right atrial bypass grafting for central venous obstruction associated with dialysis access: another treatment option. (2/1270)

PURPOSE: Central venous obstruction is a common problem in patients with chronic renal failure who undergo maintenance hemodialysis. We studied the use of right atrial bypass grafting in nine cases of central venous obstruction associated with upper extremity venous hypertension. To better understand the options for managing this condition, we discuss the roles of surgery and percutaneous transluminal angioplasty with stent placement. METHODS: All patients had previously undergone placement of bilateral temporary subclavian vein dialysis catheters. Severe arm swelling, graft thrombosis, or graft malfunction developed because of central venous stenosis or obstruction in the absence of alternative access sites. A large-diameter (10 to 16 mm) externally reinforced polytetrafluoroethylene (GoreTex) graft was used to bypass the obstructed vein and was anastomosed to the right atrial appendage. This technique was used to bypass six lesions in the subclavian vein, two lesions at the innominate vein/superior vena caval junction, and one lesion in the distal axillary vein. RESULTS: All patients except one had significant resolution of symptoms without operative mortality. Bypass grafts remained patent, allowing the arteriovenous grafts to provide functional access for 1.5 to 52 months (mean, 15.4 months) after surgery. CONCLUSION: Because no mortality directly resulted from the procedure and the morbidity rate was acceptable, this bypass grafting technique was adequate in maintaining the dialysis access needed by these patients. Because of the magnitude of the procedure, we recommend it only for the occasional patient in whom all other access sites are exhausted and in whom percutaneous dilation and/or stenting has failed.  (+info)

Factors influencing the development of vein-graft stenosis and their significance for clinical management. (3/1270)

OBJECTIVES: To assess the influence of clinical and graft factors on the development of stenotic lesions. In addition the implications of any significant correlation for duplex surveillance schedules or surgical bypass techniques was examined. PATIENTS AND METHODS: In a prospective three centre study, preoperative and peroperative data on 300 infrainguinal autologous vein grafts was analysed. All grafts were monitored by a strict duplex surveillance program and all received an angiogram in the first postoperative year. A revision was only performed if there was evidence of a stenosis of 70% diameter reduction or greater on the angiogram. RESULTS: The minimum graft diameter was the only factor correlated significantly with the development of a significant graft stenosis (PSV-ratio > or = 2.5) during follow-up (p = 0.002). Factors that correlated with the development of event-causing graft stenosis, associated with revision or occlusion, were minimal graft diameter (p = 0.001), the use of a venovenous anastomosis (p = 0.005) and length of the graft (p = 0.025). Multivariate regression analysis revealed that the minimal graft diameter was the only independent factor that significantly correlated with an event-causing graft stenosis (p = 0.009). The stenosis-free rates for grafts with a minimal diameter < 3.5 mm, between 3.5-4.5 and > or = 4.5 mm were 40%, 58% and 75%, respectively (p = < 0.05). Composite vein and arm-vein grafts with minimal diameters > or = 3.5 mm were compared with grafts which consisted of a single uninterrupted greater saphenous vein with a minimal diameter of < 3.5 mm. One-year secondary patency rates in these categories were of 94% and 76%, respectively (p = 0.03). CONCLUSIONS: A minimal graft diameter < 3.5 mm was the only factor that significantly correlated with the development of a graft-stenosis. However, veins with larger diameters may still develop stenotic lesions. Composite vein and arm-vein grafts should be used rather than uninterrupted small caliber saphenous veins.  (+info)

Frame dislocation of body middle rings in endovascular stent tube grafts. (4/1270)

OBJECTIVES: To understand the cause, and propose a mechanism for frame dislocation in endovascular grafts. MATERIALS AND METHODS: Five tube grafts were explanted due to secondary distal leakage 15-21 months after operation. One bifurcated graft was removed during emergency operation after aortic rupture caused by secondary leakage. A second bifurcated graft was harvested from a patient with thrombotic occlusion of one limb, who died after transurethral prostatic resection. The inside of the grafts were examined endoscopically. The stent was inspected after removal of the fabric, broken ligatures were counted and examined by scanning electron microscopy. The fabric strength was tested by probe puncture. RESULTS: We found 17-44% of the stent ligatures of the body middle rings to be loose. The knots were intact. Degradation of the polyester textile was not observed. CONCLUSIONS: Continuous movements in the grafted aorta and blood pressure impose permanent stress to the stent frame and the polyester fabric resulting in morphological changes in the body middle ring of grafts. The clinical implications of the suture breakages are unknown although they may be related to distal secondary leakage in tube grafts.  (+info)

Relationship of femorodistal bypass patency to clinical outcome. Iloprost Bypass International Study Group. (5/1270)

OBJECTIVE: To investigate the relationship between bypass patency, limb survival and clinical symptoms after femorodistal bypass procedures. DESIGN: Multicentre, prospectively planned 12-month postoperative follow-up. PATIENTS AND METHODS: Five hundred and seventeen patients undergoing femorodistal bypass surgery for severe ischaemia. Clinical symptoms, bypass patency were recorded at regular intervals up to 12 months postoperatively. RESULTS: Complete follow-up data was obtained on 498 patients (96%). Fifty-six (17%) of the 341 patients with patent bypasses had either rest pain or ulcers or had undergone major amputation at 12 months. Of the 167 patients with an occluded bypass, 22 patients (13%) had improved clinical symptoms and a total of 59 patients (35%) had avoided major amputation at 12 months. The clinical outcome for patients classified preoperatively as Fontaine stage IV was significantly worse than for those in stage III preoperatively despite similar bypass patency rates. CONCLUSIONS: There is a fair correlation between technical and clinical outcome after femorodistal bypass surgery at 12 months, but there are significant numbers of patients with occluded bypasses who have a good clinical outcome and of patients with patent bypasses who have a poor clinical outcome. The reporting of symptoms in addition to bypass patency would aid the interpretation of surgical results.  (+info)

Lipoprotein(a) and coronary thrombosis and restenosis after stent placement. (6/1270)

OBJECTIVES: The objective of this prospective study was to evaluate the relation between high lipoprotein(a) levels and thrombotic and restenotic events after coronary stent implantation. BACKGROUND: Lipoprotein(a) may promote atherogenesis, coronary thrombosis and restenosis after balloon angioplasty, but the clinical significance remains unclear. METHODS: The study included 2,223 consecutive patients with successful coronary stent placement. According to the serum level of lipoprotein(a), patients were divided in two groups: 457 patients of the highest quintile formed the high lipoprotein(a) group, and 1,766 patients of the lower four quintiles formed the low lipoprotein(a) group. Primary end points were the incidence of angiographic restenosis at six months and the event-free survival at one year. Secondary end point was the incidence of angiographic stent occlusion. RESULTS: Early stent occlusion occurred in four of the 457 patients (0.9%) with high and 37 of the 1,766 patients (2.1%) with low lipoprotein(a) levels, odds ratio of 0.41 (95% confidence interval, 0.15 to 1.16). Angiographic restenosis occurred in 173 of the 523 lesions (33.2%) in the high lipoprotein(a) group and 636 of the 1,943 lesions (32.7%) in the low lipoprotein(a) group, odds ratio of 1.02 (0.83 to 1.25). The probability of event-free survival was 73.0% in the high lipoprotein(a) group and 74.8% in the low lipoprotein(a) group (p = 0.45). On the basis of the findings in the low lipoprotein(a) group, the power of this study to detect a 25% increase in the incidence of restenosis and adverse events in the group with elevated lipoprotein(a) was 90% and 75%, respectively. CONCLUSIONS: Elevated lipoprotein(a) levels did not influence the one-year clinical and angiographic outcome after stent placement. Thrombotic events and measures of restenosis were not adversely affected by the presence of high lipoprotein(a) levels.  (+info)

Prospective study of health related quality of life before and after coronary artery bypass grafting: outcome at five years. (7/1270)

OBJECTIVE: To determine the long term health related quality of life of coronary artery bypass graft patients, to look at changes between one and five years after surgery, and to examine the ability of preoperative variables to predict longer term outcome. DESIGN: Nottingham health profile (NHP) was used to assess patients at five years compared to results obtained at one year. PATIENTS: 100 male patients aged < 60 years at time of surgery; 77 had three vessel disease and 84 received three or more saphenous vein grafts. RESULTS: In comparing the five year results with those at one year, lower mean scores, indicating slight improvements, were seen in the NHP dimensions of pain, sleep, social isolation, and emotional reactions, whereas signs of deterioration were noted in the physical mobility and energy scores. Chest pain was experienced by 34 of 84 patients at five years compared with 17 of 89 patients at one year. The proportion of patients who were unrestricted in their activities ranged from 61-70% at five years compared with 82-88% at one year. Absence of dyspnoea before surgery, indicating relatively good left ventricular function, was a predictor of good outcome at both one and five years. CONCLUSIONS: Evidence of deterioration in physical function is compatible with expected decline in graft patency; specific rather than generic measures were most sensitive to this change.  (+info)

Coronary artery stenting in unstable angina pectoris: a comparison with stable angina pectoris. (8/1270)

OBJECTIVE: To compare early complication rates in unselected cases of coronary artery stenting in patients with stable v unstable angina. SETTING: Tertiary referral centre. PATIENTS: 390 patients with stable angina pectoris (SAP) and 306 with unstable angina (UAP). Patients treated for acute myocardial infarction (primary angioplasty) or cardiogenic shock were excluded. INTERVENTIONS: 268 coronary stents were attempted in 211 patients (30.3%). Stents used included AVE (63%), Freedom (14%), NIR (7%), Palmaz-Schatz (5%), JO (5%), and Multilink (4%). Intravascular ultrasound was not used in any of the cases. All stented patients were treated with ticlopidine and aspirin together with periprocedural unfractionated heparin. RESULTS: 123 stents were successfully deployed in 99 SAP patients v 132 stents in 103 UAP patients. Failed deployment occurred with nine stents in SAP patients, v four in UAP patients (NS). Stent thrombosis occurred in four SAP patients and 11 UAP patients. Multivariate analysis showed no relation between stent thrombosis and clinical presentation (SAP v UAP), age, sex, target vessel, stent length, or make of stent. Stent thrombosis was associated with small vessel size (p < 0.001) and bailout stenting (p = 0.01) compared with elective stenting and stenting for suboptimal PTCA, with strong trends toward smaller stent diameter (p = 0.052) and number of stents deployed (p = 0.06). Most stent thromboses occurred in vessels < 3 mm diameter. CONCLUSIONS: Coronary artery stenting in unstable angina is safe in vessels >/= 3 mm diameter, with comparable initial success and stent thrombosis rates to stenting in stable angina.  (+info)

HypothesisPercutaneous angioplasty would provide a durable alternative to surgical revision in the treatment of infrainguinal vein graft stenosis.DesignOutcome
PhD in Cardiovascular Sciences. The application of spatial transcriptomics to the study of accelerated atherosclerosis in human vein grafts. Supervisors Mr Mustafa Zakkar, Prof Gavin Murphy
The action of MMPs has been linked to the pathological remodeling of blood vessels that constitutes the basis for cardiovascular conditions with significant mortality and morbidity. Specifically, MMP-9 has been associated with the development of lesions after vascular surgical interventions,12 appears to have a role in vein graft occlusion after coronary bypass surgery,13,14⇓ and seems to be associated with acute vascular syndromes,15,16⇓ suggesting that MMP-9 may be an attractive target for therapeutic intervention. However, lack of specificity, poor oral bioavailability, and unrelated side effects of currently available synthetic inhibitors do not allow the proper demonstration of MMP-9 involvement in pathological arterial remodeling. We thus decided to investigate the role of MMP-9 in arterial remodeling by using targeted genetic disruption of MMP-9 gene, which results in complete loss of MMP-9 expression and activity,6 and the mouse carotid artery flow cessation model. In spite of its ...
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Saphenous Vein Bypass Graft Disease Hardcover Books- Buy Saphenous Vein Bypass Graft Disease Books online at lowest price with Rating & Reviews , Free Shipping*, COD. - Infibeam.com
TY - JOUR. T1 - A New Treatment Strategy for Saphenous Vein Graft Lesions?. T2 - Letting it Go ∗. AU - Brilakis, Emmanouil S.. AU - Banerjee, Subhash. AU - Burke, M. Nicholas. PY - 2018/5/8. Y1 - 2018/5/8. KW - coronary artery bypass graft surgery. KW - native coronary artery. KW - percutaneous coronary intervention. KW - saphenous vein graft. UR - http://www.scopus.com/inward/record.url?scp=85046542322&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85046542322&partnerID=8YFLogxK. U2 - 10.1016/j.jacc.2018.03.457. DO - 10.1016/j.jacc.2018.03.457. M3 - Editorial. C2 - 29724351. AN - SCOPUS:85046542322. VL - 71. SP - 1983. EP - 1985. JO - Journal of the American College of Cardiology. JF - Journal of the American College of Cardiology. SN - 0735-1097. IS - 18. ER - ...
In the present study, the expression and causal involvement of MCP-1 in the development of IH in a mouse in vivo or a human ex vivo model of vein graft disease is demonstrated. MCP-1 expression was shown to be present in the murine vein graft and was also detectable in a HSV organ culture. Blocking the CCR2/MCP-1 pathway, using the receptor antagonist 7ND-MCP-1, resulted in a reduced vein graft thickening in both the murine vein graft and in HSV segments. Furthermore, we demonstrate that reduced vein graft thickening, besides the effect on monocyte chemotaxis, is caused by a direct antiproliferative effect of 7ND-MCP-1 on vascular SMCs.. Vein graft thickening attributable to development of IH and accelerated atherosclerosis is the major limitation in the long-term survival of patent vein grafts. The mechanism of vein graft thickening development is largely unknown, but it is assumed that it is caused by an inflammatory response to damage of the graft.9,10. MCP-1 is a well-known proinflammatory ...
Dr. Mehilli will present the study Long-term Outcomes After Use of Drug-Eluting Stents and Bare-Metal Stents for the Treatment of Saphenous Vein Graft Lesions: Results of the Randomized ISAR-CABG Trial on Monday, April 4 at 10:45 a.m. CDT in the Joint Main Tent: La Nouvelle. The American College of Cardiology (www.cardiosource.org) represents the majority of board certified cardiovascular care professionals through education, research, promotion, development and application of standards and guidelines - and to influence health care policy. ACC.11 is the largest cardiovascular meeting, bringing together cardiologists and cardiovascular specialists to share the newest discoveries in treatment and prevention, while helping the ACC achieve its mission to address and improve issues in cardiovascular medicine ...
Objectives: The mechanisms of early vein graft failure after coronary artery bypass graft (CABG) surgery remains unclear. We hypothesized that insufficiency of DNA repair pathway in human vein graft is related to early graft failure.. Methods: Human internal mammary arteries (IMA) and saphenous veins (SV) samples were obtained from coronary artery bypass grafting surgery. Among 118 SV segments, there was 9% vein grafts had early grafting failure within 7 days which is determined by Multichannel-EKG-gated CT angiography (Philips Medical). In contrast, there was no early graft failure in 28 IMA grafts. Human IMA or SV segments (1 X 1 mm) were incubated in organ culture system in the absence or presence of 1% H2O2 for 24 hours with 20% O2. DNA damage was determined by 8-oxoG staining, and DNA repair pathways were investigated by MYH (DNA mismatch repair) immunohistochemical staining. Apoptotic level was evaluated by TUNEL staining and DNA gel analysis. The positive staining rate was determined by ...
TY - JOUR. T1 - Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development. T2 - Implications for the Treatment of Vein Graft Failure. AU - Koga, Jun Ichiro. AU - Nakano, Toshiaki. AU - Dahlman, James E.. AU - Figueiredo, Jose Luiz. AU - Zhang, Hengmin. AU - Decano, Julius. AU - Khan, Omar F.. AU - Niida, Tomiharu. AU - Iwata, Hiroshi. AU - Aster, Jon C.. AU - Yagita, Hideo. AU - Anderson, Daniel G.. AU - Keith Ozaki, C.. AU - Aikawa, Masanori. PY - 2015/11/1. Y1 - 2015/11/1. N2 - Objective-Despite its large clinical impact, the underlying mechanisms for vein graft failure remain obscure and no effective therapeutic solutions are available. We tested the hypothesis that Notch signaling promotes vein graft disease. Approach and Results-We used 2 biotherapeutics for Delta-like ligand 4 (Dll4), a Notch ligand: (1) blocking antibody and (2) macrophage-or endothelial cell (EC)-targeted small-interfering RNA. Dll4 antibody administration for 28 days inhibited vein graft lesion ...
Despite advances in endovascular strategies, surgical infrainguinal lower limb revascularization remains the gold standard treatment for critical lower limb ischemia and disabling claudication. Maintaining patency of infrainguinal vein bypass grafts has been a challenging task for vascular surgeons as they are prone to developing stenoses which may precipitate failure of the bypass. Duplex ultrasound scanning has evolved as the investigation of choice to identify vein graft lesions but graft surveillance programs using this technique remain controversial. The rationale for graft surveillance is that intervention in a patent but failing graft results in improved long-term patency and limb salvage rates compared to rescue of an occluded graft. The six-week postoperative Duplex ultrasound scan is important in identifying flow abnormalities that can predict the natural history of a vein graft and the outlook for the limb in the medium term. There are multiple factors influencing vein graft failure, ...
This investigation reveals that human vein grafts very soon after CABG show distinct changes. These changes are characterised by loss of surface lining endothelial cells, insudation of blood corpuscular elements such as polymorphonuclear leucocytes and monocytes, admixed with a fibrin-platelet thrombus, the appearance of vimentin positive, actin negative spindle shaped cells, and absence of actin positive SMCs in the pre-existent media topographically related to the sites of neointimal reaction. These observations allow speculations as to the mechanisms involved in neointimal thickening.. Denudation of the surface endothelial cell lining appears to be a crucial factor, and its extent and severity may eventually determine graft patency. Loss of endothelial cells, as observed in veins 2-9 days after grafting, is accompanied by insudation with polymorphonuclear leucocytes, blood monocytes, and T lymphocytes. To this end our observations fit with previous experimental works. Brody and colleagues11 ...
The hemodynamics of 56 femorodistal saphenous vein bypasses (in situ [n = 53] or reversed [n = 3]) identified to have residual or recurrent graft stenoses were characterized with Doppler-derived blood flow velocity and resting limb systolic pressure measurements. The magnitude and configuration of the graft blood flow velocity waveform were the best predictors of graft stenosis. Transformation of the graft blood flow velocity waveform from a triphasic to a monophasic or biphasic configuration coupled with a low (less than 45 cm/sec) or decrease (greater than 30 cm/sec) in peak systolic blood flow velocity relative to initial postoperative levels reliably predicted the presence of a remote occlusive lesion. In 20 (36%) of the 56 limbs, the ankle-brachial systolic pressure index (ABI) did not identify graft stenosis. The low sensitivity of ABI in the identification of graft stenosis was due to insignificant decrease (less than 0.15) of ABI (n = 11), incompressibility of the tibial arteries (n = 6), or
TY - JOUR. T1 - Diffusa ectasia e aneurisma focale di un by-pass venoso aorto-coronarico. AU - Lucreziotti, Stefano. AU - Sponzilli, Carlo. AU - Castini, Diego. AU - Salerno, Diego. AU - Bosotti, Laura. AU - Lombardi, Federico. PY - 2007/4. Y1 - 2007/4. N2 - Saphenous vein graft disease is a continuum process which develops from the very early post-surgical period. Although progressive obstruction is the most common feature of SVG disease, severe dilatation with patterns of diffuse ectasia, aneurysm, or pseudoaneurysm may rarely occur. The present article describes a case of an aorto-coronary vein graft presenting an angiographic pattern of diffuse ectasia with a focal aneurysm.. AB - Saphenous vein graft disease is a continuum process which develops from the very early post-surgical period. Although progressive obstruction is the most common feature of SVG disease, severe dilatation with patterns of diffuse ectasia, aneurysm, or pseudoaneurysm may rarely occur. The present article describes a ...
We have shown for the first time to our knowledge that even in the absence of atherosclerosis, the majority of vein graft neointimal and medial cells derive from precursors that are extrinsic to the vein at the time of grafting. We have also provided the first evidence that the arterializing vein graft wall develops largely from focal expansions of progenitor cells, which originate within and outside of the vein graft at the time of implantation. Finally, we have shown that endothelial remodeling of vein grafts is accomplished by the expansion of graft-intrinsic as well as graft-extrinsic cells, and that BM-derived cells participate in this process. Importantly, these novel insights into vein graft biology derive from a murine vein graft system that we have shown to model human vein grafts, with regard to their surgical anastomoses as well as the distribution, composition and extent of neointimal hyperplasia within the grafts.12. Sources of graft-extrinsic neointimal cells in our murine model ...
This thesis investigates the principal factors responsible for early failure of femorodistal vein grafts. Chapter 1 provides an overview of severe lower limb ischaemia which is their principal indication. Chapter 2 outlines the role of surgery in the management of the severely ischaemic limb, concentrating on the development of distal bypass using autogenous vein. Chapter 3 considers the multiple causes of vein graft failure, concentrating on the early period and includes an account of currently employed methods designed to reduce the problem. Chapter 4 is a retrospective review of the results of 130 in situ vein grafts performed at Leicester Royal Infirmary in the 8 year period prior to the commencement of this study. The primary early failure rate was 30%, with two thirds of patients undergoing amputation. Chapter 5 outlines the methods used in a series of 42 patients undergoing distal vein bypass. Preoperative assessment included arteriography and 3 methods using Doppler ultrasound. Doppler ...
To the editor: I am responding to a statement made by Farry and associates in a recent case report (Development of Atherosclerosis in Saphenous Vein Coronary Bypass Graft, Ann Intern Med 85:478-479, 1976).. The authors state that the occurrence of atherosclerosis in aortocornary saphenous vein bypass grafts had not been described before their report. This is not true; our group in Milwaukee has previously reported several such instances (see references below). ...
Orlando, Fla.The addition of clopidogrel to aspirin did not lead to a significant reduction in vein graft intimal hyperplasia during the first year after CABG, according to the CASCADE trial presented Monday during the late-breaking clinical trials session at the 2009 American Heart Association conference.
Patients who develop in-stent restenosis constitute a peculiar technical challenge for both interventional cardiologists and cardiac surgeons. Indeed, once anatomical and technical factors have been ruled out, the occurrence of stent failure can identify a subset of patients with particularly aggressive coronary atherosclerosis in whom successful revascularization can be difficult to achieve using either percutaneous or surgical methods. In fact, in the cardiology literature, there is consistent evidence that the percutaneous retreatment of these cases leads to suboptimal clinical results and is associated with an high risk of additional restenosis or occlusion.1-4 Although this issue has not been specifically investigated in surgical series, it is at least likely that even coronary bypass conduits can be damaged by the aggressive atherosclerotic process and develop accelerated graft disease and failure.. The present protocol was conceived to investigate the results of surgical revascularization ...
Among patients undergoing CABG surgery, the use of endoscopic vein-graft harvesting compared with open vein-graft harvesting was not associated with increased mortality.
Short-term success in reopening stenotic vessels is high, but recurrent stenosis affects a substantial number of patients. Stenting after angioplasty has improved the restenosis rate, but even stented lesions can become clogged over time. Saphenous vein coronary bypass grafts have high rates of stenosis, and angio-plasty of these grafts is often challenging, so any method to prevent blockages in these vessels would be welcome. Waksman and colleagues examined the effects of intravascular radiation therapy on the prevention of restenosis of blocked bypass grafts that had been successfully revascularized.. The investigators enrolled 120 patients who had just undergone revascularization of a blocked graft via angioplasty, laser ablation, or atherectomy drill, followed by stenting. Patients were randomized to brief placement of a thin intravascular ribbon at the stent site with iridium-impregnated or nonradioactive seeds. Patients were eligible only if they had vessel stenoses of certain dimensions ...
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A person with severely diseased arteries in the leg(s), can experience pain on walking only short distances (critical claudication), pain at rest, or death of tissues in the leg. When the main thigh artery has a long blockage, the best option is to insert a bypass to carry the blood from an artery with good blood flow to the affected artery below the block. Bypass is intended to save limbs that might otherwise require amputation. The different types of material available to create the bypass include the persons own vein (autologous vein), human umbilical vein (HUV) and synthetic materials polytetrafluoroethylene (PTFE) or Dacron, alone or with the blood thinning agent heparin bonded to the inside of the graft. It has been clear for some time that bypass grafts extending to below the knee do not remain patent with good blood flow as well as do above the knee grafts. The aim of this review was to determine the most effective type of material. We identified 13 randomised controlled trials that ...
The findings of ST in the SYNTAX trial are notable in that early (,30 days) and late/very late ARC definite ST (,30 days) were associated with short-term and long-term mortality. It is important to emphasize that the actual causes of death are multifactorial and not easily directly attributed to ST. For example, although lack of post-procedural antiplatelet therapy was the strongest independent predictor of ST (Table 3), a recent substudy of the SYNTAX trial showed that this was of multifactorial origin (9). Factors precluding antiplatelet administration were reported to include gastrointestinal bleeding, retroperitoneal bleeding from procedure-related femoral vascular access, coronary perforation, or following surgical bailout for PCI-related complications. Consequently, directly attributing ST to mortality is difficult, although it is clear there was a strong causal link.. In addition, ST most frequently occurred in the left main and proximal vasculature (,70% of cases). Accordingly, the ...
We can assume that the cellular content and proportions of different cell types in the HSCT graft are important in safe and efficient HSCT, as is also the spectrum of cytokines the cells secrete. However, there are no systematic studies on the immunological content of clinical HSCT grafts. In current HSCT protocols, the cell and cytokine profile of the graft is not characterized.. In the project we systematically characterise the immune cell profiles of clinical HSCT grafts and study their associations with the outcome of HSCT. From all grafts we estimate the numbers of the following cell populations ...
What is SVG? What Opens a SVG? File Format List from - Background There are number of unanswered questions related to reading and parsing SVG paths: Easiest way to read in svg path data with Java? Re: parsing a svg file
Dears, i have created an svg rect inside a group and i have make this svg group to have transformOrigin:center center explicitly then draw a little blue circle at this group returned position my question is when i am trying to rotate the svg group then resize it the return location is wrong and ...
Dr. KORAY ERDOGAN - ASMED CLINIC - 5004 grafts - MANUAL FUE PATIENTS AGE: 40 NW: 5 Total transplanted area: 130 cm2 Total donor capacity: 8600 grafts
Percutaneous coronary intervention of degenerated saphenous vein grafts remains relatively high risk when compared to native vessel interventions, despite advances in pharmacotherapy and embolic protection. This article discusses the phenomenon of distal embolization that seems to plague saphenous vein graft interventions, reviews device-based strategies for embolic protection, and offers a perspective on the utility of percutaneous saphenous vein graft intervention in both elective and acute settings.. ...
TY - JOUR. T1 - Contemporary use of embolic protection devices in saphenous vein graft interventions. T2 - Insights from the stenting of saphenous vein grafts trial. AU - Badhey, Neeraj. AU - Lichtenwalter, Christopher. AU - de Lemos, James A. AU - Roesle, Michele. AU - Obel, Owen. AU - Addo, Tayo A. AU - Haagen, Donald. AU - Abdel-Karim, Abdul Rahman. AU - Saeed, Bilal. AU - Bissett, Joseph K.. AU - Sachdeva, Rajesh. AU - Voudris, Vassilios V.. AU - Karyofillis, Panagiotis. AU - Kar, Biswajit. AU - Rossen, James. AU - Fasseas, Panayotis. AU - Berger, Peter B.. AU - Banerjee, Subhash. AU - Brilakis, Emmanouil S. PY - 2010/8/1. Y1 - 2010/8/1. N2 - Background: We sought to evaluate the contemporary use of embolic protection devices (EPDs) in saphenous vein graft (SVG) interventions. Methods: We examined EPD use in the stenting of saphenous vein grafts (SOS) trial, in which 80 patients with 112 lesions in 88 SVGs were randomized to a bare metal stent (39 patients, 43 grafts, and 55 lesions) or ...
Dive into the research topics of Treatment of no-reflow in degenerated saphenous vein graft interventions: Comparison of intracoronary verapamil and nitroglycerin. Together they form a unique fingerprint. ...
Coronary artery bypass grafting is an effective treatment for myocardial ischaemia and is particularly important in patients with multivessel disease and diabetes. However, up to 40% of saphenous vein grafts will occlude within 10 years of surgery. T
BACKGROUND: Externally stenting saphenous vein grafts reduces intimal hyperplasia, improves lumen uniformity and reduces oscillatory shear stress 1 year following surgery. The present study is the first to present the longer-term (4.5 years) performance and biomechanical effects of externally stented saphenous vein grafts. METHODS: Thirty patients previously implanted with the VEST external stent in the randomized, within-patient-controlled VEST I study were followed up for adverse events; 21 of these were available to undergo coronary angiography and intravascular ultrasound. RESULTS: Twenty-one stented and 29 nonstented saphenous vein grafts were evaluated by angiography and ultrasound at 4.5 ± 0.3 years. Vein graft failure rates were comparable between stented and nonstented grafts (30 and 23% respectively; p = 0.42). All failures were apparent at 1 year except for one additional nonstented failure at 4.5 years. In patent vein grafts, Fitzgibbon perfect patency remained significantly higher in the
OBJECTIVES. To gain insight into the mechanism of stenting in humans and its short- and long-term implications, we studied the vascular wall of saphenous vein aortocoronary bypass grafts after implantation of the Wallstent. BACKGROUND. The implantation of a stent in aortocoronary bypass grafts may provide an alternative solution for revascularization in patients who are poor candidates for reoperation. Because human histopathologic findings after stenting with the Wallstent have not previously been described in detail, we examined graft segments that were surgically retrieved from 10 patients (21 stents) at 3 days to 10 months after implantation of the stent. METHODS. The grafts were examined by a combination of the following techniques: light microscopy, immunocytochemistry and both scanning and transmission electron microscopy. RESULTS. Early observations revealed that large amounts of platelets and leukocytes adhered to the stent wires during the first few days. At 3 months, the wires were ...
The saphenous vein, which runs from the ankle to the groin along the inside of the leg, is commonly used as a graft for people undergoing a CABG surgery. The vein is removed from the leg and reattached to the heart to create a detour around the blocked part of a coronary artery. Following this procedure, many people are prescribed aspirin as a way to increase the chance that the graft procedure will be successful. However, saphenous vein graft failure may still occur in some people, indicating a need to understand why this happens and who might be at risk for graft failure. Thrombin, a protein involved in the blood clotting process, is somehow related to aspirin resistance, abnormalities in blood flow, and cell disruption within the saphenous vein, all factors thought to increase the risk of graft failure. The purpose of this study is to evaluate the likelihood that a burst in thrombin contributes to graft failure in people who have recently undergone a CABG procedure using the saphenous ...
The saphenous vein, which runs from the ankle to the groin along the inside of the leg, is commonly used as a graft for people undergoing a CABG surgery. The vein is removed from the leg and reattached to the heart to create a detour around the blocked part of a coronary artery. Following this procedure, many people are prescribed aspirin as a way to increase the chance that the graft procedure will be successful. However, saphenous vein graft failure may still occur in some people, indicating a need to understand why this happens and who might be at risk for graft failure. Thrombin, a protein involved in the blood clotting process, is somehow related to aspirin resistance, abnormalities in blood flow, and cell disruption within the saphenous vein, all factors thought to increase the risk of graft failure. The purpose of this study is to evaluate the likelihood that a burst in thrombin contributes to graft failure in people who have recently undergone a CABG procedure using the saphenous ...
HistoryA 48-year-old man underwent three-vessel aortocoronary bypass graft for unstable angina and high-grade occlusive coronary artery disease. Postoperatively
Background Saphenous vein grafts develop an aggressive atherosclerotic process and the efficacy of drug eluting stents (DES) in treating saphenous vein graft (SVG) lesions has not been convincingly demonstrated. The aim of this study was to review and analyze the current literature for controlled studies comparing DES versus bare metal stents (BMS) for treatment of SVG stenoses. Methodology/Principal Findings We searched several scientific databases and conference proceedings up to March 15, 2010 for controlled studies comparing target vessel revascularization (TVR) between DES and BMS. Summary odds ratios (OR) for the primary endpoint TVR and secondary endpoints infarction, stent thrombosis and death were calculated using random-effect models. A total of 29 studies (3 randomized controlled trials RCT) involving 7549 (202 in RCT) patients were included. The need for target vessel revascularization in the DES group tended to be lower compared to BMS for the 3 RCT (OR 0.50 [0.24-1.00]; p = 0.051) and for
Aneurysmatic degeneration of saphenous vein coronary artery grafts is a rare complication that generally appears late. Most of these cases are asymptomatic, although they may also be accompanied by angina, heart attack or dyspnea. The suspected diagnosis should be made when a mediastinal mass is discovered in the thoracic x-ray of a patient with a history of coronary revascularization. A computerized tomography and coronary angiography should be performed in order to confirm the diagnosis.. Due to the significant morbidity and mortality risk inherent to the risk of rupture, embolization or heart attack, surgery to remove or exclude the aneurysm should be considered as definitive treatment.. ...
The use of embolic protection devices (EPDs) when treating coronary saphenous vein bypass grafts, performing carotid arterial stenting and treating acute coronary syndromes is well accepted.
Introduction: Acknowledging the superior long term patency of infrainguinal saphenous bypass to distal popliteal artery, debate continues regarding the choice of alternative conduits and possible surgical adjuncts to improve inflow and graft salvage. The objective of this retrospective study was to determine the effectiveness of proximal anastomotic patch as adjunct to open surgical below the knee popliteal revascularization.. Material and Methods: In a series of 132 distal popliteal bypass operations 63 non-reversed vein, 18 in situ vein and 51 Omniflow bypass conduits were used. Proximal anastomotic patch was applied in overall 28 patients: 19% in the non-reversed (12 patients), 50% in the in situ group (9 patients) and 13.7% in the Omniflow group (7 patients).. Results: The reintervention rate was 7.9% in the non-reversed, 33.3% in the in situ and 31.4% in the Omniflow group. The most often complication was the proximal anastomotic stenosis (5.3%), followed by bleeding (3%), infection (1.5%) ...
Despite the fact that stents have improved the outcome of percutaneous intervention of obstructed vein grafts (2,3), prognosis of patients undergoing this procedure is still poor (4,12). Targets to improve intervention in saphenous vein grafts are to inhibit distal embolization of atherosclerotic debris (13)and to reduce restenosis rate, which is elevated compared with native vessels (2,4,14). Thus, it was intriguing to hypothesize that a stent covered with a membrane would seal the lumen and prevent protrusion of proliferating tissue and, thereby, reduce microembolization and restenosis rate. However, the present trial does not reveal a benefit of the PTFE-membrane-covered Jostent Stentgraft compared with the conventional stent used (Jostent Flex); restenosis rate, the primary end point, did not significantly differ between the Stentgraft (29%) and the conventional stent group (20%). In addition, acute complications and long-term clinical event rate up to 15 months were comparable between the ...
In this study we investigated to find out one of the best preparation technique by the effect of different solutions on venous morphology for harvested saphenous vein graft for CABG. Saphenous veins harvested from 10 patients were divided into three groups, and saphenous veins were divided to 3 cm segments. Group I was the control group and saphenous vein graft was enlarged by 20 mmHg, in Group II saphenous vein graft put in isotonic sodium chloride for 20 minutes and enlarged by 100 mmHg, and Group III saphenous vein graft was put in nitroprusside for 20 minutes and enlarged by 100 mmHg pressure. All saphenous vein segments were examined under light microscope for endothelial cell deprivation, intimal and medial edema and scored from 0 to 3. Mean scores were collected as datas. In nitroprusside group all scoring datas were better. As a result we found out that nitroprusside was having better protective effect on saphenous vein endothelium ...
Over a million coronary bypass procedures using human saphenous vein (HSV) are performed yearly worldwide. Nearly half of these grafts fail over a period of 12...
Dr Joye believes that there are many other possible applications for cryoplasty in the vascular field. Joyce said: We are investigating coronary applications for native coronary areas, bypass grafts and for vulnerable plaque treatment. In the peripheral arena we are exploring applications for limb salvage and dialysis graft treatment to name a few.. One concern over cryoplasty is its anticipated cost compared to other procedures. A cryoplasty balloon will certainly cost more than an existing PTA balloon. However, by contrast, it will cost significantly less than a drug-eluting stent, explained Joye.. Joye contends, In the real world, as at least half of lesions are dilated and stented, the cost per procedure is actually significantly less with cryoplasty He added, The more complex the lesion, the greater the cost advantage, because instead of the incremental cost of each successive stent, cryoplasty has a nominal cost associated with each inflation. As an example he stated, A 30cm ...
Semantic Scholar extracted view of Atherosclerosis and aneurysm formation in a saphenous vein-graft. by Alberto G de la Rocha et al.
I have another one that I think I have, but want to check to make sure. Any help would be greatly appreciated. Indications: A 70 year old with history
Is it possible that youre overpaying for biological surgical grafts? When you purchase grafts direct from Select Surgical Technologies, youll cut out the
Is it possible that youre overpaying for biological surgical grafts? When you purchase grafts direct from Select Surgical Technologies, youll cut out the
Im Einsatzgebiet können die Haare lang bleiben. Mit der U-FUE Classic können alle Haare lang bleiben!. → U FUE Classic ...
... graft occlusion, vascular MeSH C23.550.767.600 - malignant hyperthermia MeSH C23.550.767.700 - pain, postoperative MeSH C23.550 ... vascular fistula MeSH C23.300.575.950.150 - arterio-arterial fistula MeSH C23.300.575.950.250 - arteriovenous fistula MeSH ...
French vascular surgeon Jacques Oudot performed the first arterial graft on a human being, operating at a Paris hospital on a ... 51-year-old woman with aortic occlusion of the left leg. The patient reportedly made a successful recovery. Carbon-14 dating of ... A History of Vascular Surgery. 2d.Ed. (John Wiley & Sons, 2008) pp82, 197-198 James VanderKam and Peter Flint, The Meaning of ...
Vascular and Interventional Radiologists are at the forefront of treating a wide variety of vascular diseases. Since its ... If an occlusion is too dense or complex, a bypass could also be performed, where two segments of vessel are bridged by an ... Stents and stent-grafts: Stents are used to provide a scaffold along a segment of diseased vessel. These are available in a ... An Arteriovenous Graft (AVG) relies on the same principle but bridges the gap between the artery and vein with a medical-grade ...
Risks of the bypass: Acute graft occlusion is the occlusion (blockage) of a vascular bypass graft shortly after the bypass is ... Arteries can also serve as vascular grafts. A surgeon sews the graft to the source and target vessels by hand using surgical ... In general, someone's own vein (autograft) is the preferred graft material (or conduit) for a vascular bypass, but other types ... In the legs, bypass grafting is used to treat peripheral vascular disease, acute limb ischemia, aneurysms and trauma. While ...
Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) for hemorrhage control, angioembolization and stent grafts ... October 1995). "[Initial experience with transluminally placed endovascular grafts for the treatment of complex vascular ... Stent grafts, or endo-grafts, are a more permanent solution in the hemodynamically unstable patient and are an important part ... Vascular access is based on the Seldinger technique. After puncturing the vessel with a needle and confirmation of arterial ...
Zhen Y. Jiang et al, "Characterization of Multiple Signaling Pathways of Insulin in the Regulation of Vascular Endothelial ... the EMA also granted Aganirsen an Orphan drug designation for ischemic Central retinal vein Occlusion (iCRVO). A randomised, ... granted Gene Signal orphan designation for aganirsen for the prevention of corneal graft rejection associated with excessive ... and vascular endothelial growth factor (P < 0.01). In April 2007, the EMA's Committee for Orphan Medicinal Products (COMP) ...
Prosthetic vascular grafts in the aorta Aortic aneurysm Aortofemoral grafts Sepsis Since the device is placed in the femoral ... Placing the balloon too distal from the aortic arch may induce occlusion of the renal artery and subsequent kidney failure. ... Mechanical failure of the balloon itself is also a risk which entails vascular surgery to remove under that circumstance. After ... Percutaneous coronary angioplasty In high risk coronary artery bypass graft surgery where cardiopulmonary bypass time was ...
More options for sites to place a graft are available, because the graft can be made quite long. Thus a graft can be placed in ... This results in scarring and narrowing of the vein, often to the point of occlusion. This can cause problems with severe venous ... In the latter two, needles are used to puncture the graft or fistula each time dialysis is performed. The type of vascular ... AV grafts are at high risk to develop narrowing, especially in the vein just downstream from where the graft has been sewn to ...
Vessel occlusion increases vascular resistance and therefore leads to hypertension. In portal hypertension, the vessels ... Human umbilical vein graft Ductus venosus Coté, Charles J.; Lerman, Jerrold; Todres, I. David (2009). A Practice of Anesthesia ... Diagram of the vascular channels in a human embryo of the second week. Human embryo with heart and anterior body-wall removed ... Wang, Y. Vascular biology of the placenta. in Colloquium Series on Integrated Systems Physiology: from Molecule to Function. ...
... early graft occlusion may occur.[11]. For these reasons, invasive treatment should not be performed in the acute and active ... Other fundoscopic findings include vascular sheathing (23.7%),[7] retinal hemorrhage (9%),[7] macular edema (11.3%),[7] branch ... Vasculitis resulting in occlusion of the vessels supplying the optic nerve may be the cause of acute optic neuropathy and ... Neurological involvements range from aseptic meningitis to vascular thrombosis such as dural sinus thrombosis and organic brain ...
... early graft occlusion may occur.[citation needed] For these reasons, invasive treatment should not be performed in the acute ... Blood vessel problems are observed in 7-29% of people with arterial lesions representing 15% of vascular lesions. Arterial ... Most common arterial lesions are occlusions or stenosis and aneurysms or pseudoaneurysms.[citation needed] The cause is not ... Other fundoscopic findings include vascular sheathing (23.7%), retinal hemorrhage (9%), macular edema (11.3%), branch retinal ...
Subclavian steal syndrome Vascular resistance Arteriolar vasodilator Gould KL (August 1989). "Coronary steal. Is it clinically ... Kern MJ (1996). "Coronary steal through anomalous internal mammary artery graft treated by ligation without sternotomy". Tex ... "Direct assessment of coronary steal and associated changes of collateral hemodynamics in chronic total coronary occlusions". ...
... over the months following a vascular procedure, such as the implantation of a stent-graft. Late loss is one metric that is ... An occlusion, or the blocking of all blood flow through a vessel, is considered 100% percent diameter stenosis. Binary ... reacts to the stent-graft via smooth muscle proliferation, etc., which literally pushes the stent-graft back, narrowing the ... For instance, the implantation of a stent-graft will first provide an acute gain in lumen diameter. In other words, there is an ...
Anti-vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion PMID 23440840 https://doi ... Staples versus sutures for closing leg wounds after vein graft harvesting for coronary artery bypass surgery PMID 20464762 ... Done Anti-vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema PMID 29669176 ... Done Anti-vascular endothelial growth factor for choroidal neovascularisation in people with pathological myopia PMID 27977064 ...
At least one vein and one artery (which constitutes the vascular pedicle) are dissected. The vein and artery (vascular pedicle ... Sometimes a Split Thickness Skin graft (STSG) may be performed and placed on top of the defect site and/or the donor site. The ... the jawbone and the dental occlusion. Type of defects include: Reconstruction of post-traumatic defects: Some areas of the body ... The free flap is brought up to the defect area, and the vein and artery from the flap (vascular pedicle) are anastomosed (re- ...
In general, occlusions greater than 70% of the width of the vessel lumen are thought to require intervention. However, in cases ... Vascular closure devices can be used to speed along hemostasis. Much equipment is required for a facility to perform the ... as coronary artery bypass grafting may be done at the same time Risk stratification for high cardiac risk surgeries (e.g., ... technique is also used to assess the amount of occlusion (or blockage) in a coronary artery, often described as a percentage of ...
Full-thickness skin graft to hand (86.62) Other skin graft to hand (86.63) Full-thickness skin graft to other sites (86.64) ... Other shunt or vascular bypass (39.3) Suture of vessel (39.4) Revision of vascular procedure (39.5) Other repair of vessels ( ... Bilateral endoscopic destruction or occlusion of fallopian tubes (66.3) Other bilateral destruction or occlusion of fallopian ... Free skin graft (86.60) Free skin graft, not otherwise specified (86.61) ...
Stent occlusion because of thrombosis may occur during the procedure, in the following days, or later. The presence of thrombi ... Coronary artery bypass graft surgery is the best treatment for some patients. Differences between outcomes with stenting and ... Finn AV, Nakazawa G, Joner M, Kolodgie FD, Mont EK, Gold HK, Virmani R (2007). "Vascular responses to drug eluting stents: ... coronary-artery bypass grafting in multivessel coronary disease". N. Engl. J. Med. 358 (4): 331-41. doi:10.1056/NEJMoa071804. ...
"Aortic graft infection: is there a place for partial graft removal?". European Journal of Vascular and Endovascular Surgery. 14 ... hypogastric artery occlusion, prior aortic repair and perioperative hypotension. Unlike traditional aortic repair, standard ... Type IV - Leakage through the graft wall due to the quality (porosity) of the graft material. Seen in first-generation grafts, ... Endograft migration, aneurysm rupture, graft limb stenosis/kinking, type I/III/IV endoleaks, stent graft thrombosis, or ...
CABG involves grafting new blood vessels to provide a new route for blood flow around the blocked vessel. Choice of treatment ... Plaques in the walls of the coronary arteries can rupture, resulting in occlusion of the artery and deprivation of blood flow ... Vascular Health and Risk Management. 6: 635-656. doi:10.2147/vhrm.s7564. ISSN 1178-2048. PMC 2922325. PMID 20730020. Reed, ... These medications help to prevent clots in the coronary artery and the occlusion which can lead to a heart attack. Angiotensin- ...
... can inflate the balloon at the occlusion site in the vascular system to flatten or compress the plaque against the vascular ... This procedure is done by placing a graft between the subclavian artery and the ipsilateral pulmonary artery to restore the ... The Cardiologist will thread this sheath through the vascular system to access the heart. This sheath has a balloon and a tiny ... Vascular disorders such as atherosclerosis and peripheral arterial disease cause significant morbidity and mortality in aged ...
Also, people with a higher risk of AF, e.g., people with pre-operative hypertension, more than three vessels grafted, or ... There is tentative evidence that left atrial appendage occlusion therapy may reduce the risk of stroke in people with non- ... Atrial fibrillation has been independently associated with a higher risk of developing cognitive impairment, vascular dementia ... It is strongly associated with age, preoperative hypertension, and the number of vessels grafted. Measures should be taken to ...
When surgery is required, particularly when there is a severe disfiguration of the jaw, it is common to use a rib graft to help ... occlusion). Patients can also benefit from a Bone Anchored Hearing Aid (BAHA). The condition is also known by various other ... when some form of vascular problem such as blood clotting leads to insufficient blood supply to the face. This can be caused by ... or costochondral graft. The treatment is based on the type of severity for these patients. According to Pruzanksky's ...
"Rationale of hyperbaric oxygenation in cerebral vascular insult". Current Vascular Pharmacology. 8 (1): 35-43. doi:10.2174/ ... "Skin Grafts and Flaps Compromised". Retrieved 2011-08-21. Undersea and Hyperbaric Medical Society. "Thermal Burns". Retrieved ... "Central Retinal Artery Occlusion". Retrieved 2014-05-30. Undersea and Hyperbaric Medical Society. "Clostridal Myositis and ... Skin grafts and flaps (compromised); Thermal burns. Evidence is insufficient to support its use in autism, cancer, diabetes, ...
... can inflate the balloon at the occlusion site in the vascular system to flatten or compress the plaque against the vascular ... This procedure is done by placing a graft between the subclavian artery and the ipsilateral pulmonary artery to restore the ... "Journal of Vascular Surgery. 49 (5): 1348-54. doi:10.1016/j.jvs.2008.12.046. PMID 19394559. Retrieved 2009-06-20.. ... The Cardiologist will thread this sheath through the vascular system to access the heart. This sheath has a balloon and a tiny ...
... treatment for atherosclerosis and be more prone to restenosis relative to vascular bypass or coronary artery bypass grafting. ... A small vessel diameter, the presence of posterior calcification, occlusion, hematoma, or an earlier placement of a bypass ... Access to the vascular system is typically gained percutaneously (through the skin, without a large surgical incision). An ... McTaggart, R. A.; Raghavan, D.; Haas, R. A.; Jayaraman, M. V. (June 1, 2010). "StarClose Vascular Closure Device: Safety and ...
EVH has been associated with higher risk of vein graft stenosis and occlusion. The solutions in which vein grafts are stored ... A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association". Circulation. ... In medicine, vein graft failure (VGF) is a condition in which vein grafts, which are used as alternative conduits in bypass ... The reasons why some of the grafts progress to clinical stenosis is unknown. The patency rates of saphenous vein grafts after ...
"Prosthetic graft infections involving the femoral artery." Journal of Vascular Surgery (2013). Smith, Jillian K., et al. "Does ... "Selective external endarterectomy in patients with ipsilateral symptomatic internal carotid artery occlusion." Journal of ... These include: Vascular Study Group of New England (VSGNE), a regional vascular surgery database. Vascular Quality Initiative ( ... angioplasty vs bypass graft". Journal of Vascular Surgery. 54 (4): 1021-1031. doi:10.1016/j.jvs.2011.03.281. PMID 21880457. ...
The internal mammary artery or saphenous vein can be used as grafts. The grafts are used to provide an alternate path for blood ... Occlusion of the ophthalmic artery results in blindness. Suspicion of GCA necessitates immediate treatment with glucocorticoids ... For example, medical treatment of atherosclerosis tends to be managed by cardiologists while vascular surgery repairs aneurysms ... Coronary artery bypass surgery (CABG): Grafting an artery or vein from elsewhere to bypass a stenotic coronary artery. ...
Damage to the endothelium, the interior of the vessel, has been shown to increase the likelihood of graft occlusion or blockage ... Allen KB (2005). "Endoscopic Vascular Harvest in Coronary Artery Bypass Grafting Surgery: A Consensus Statement of the ... Allen K (2005). "Endoscopic Vascular Harvest in Coronary Artery Bypass Grafting Surgery: A Consensus Statement of the ... "Endoscopic Vascular Harvest in Coronary Artery Bypass Grafting Surgery: A Meta-Analysis of Randomized Trials and Controlled ...
However, recurrence of the disease in the donor graft may happen. Superficial corneal dystrophies do not need a penetrating ... Ocular ischemic syndrome / Central retinal vein occlusion. *Central retinal artery occlusion. *Retinopathy *diabetic ...
Small incisions are made and grafts are placed individually according to the amount of hair in each follicle, eyebrows single. ... Ocular ischemic syndrome / Central retinal vein occlusion. *Central retinal artery occlusion. *Branch retinal artery occlusion ...
Medical grafting. *Bone grafting. *Skin grafting. *Vascular grafting. Organ donation. *Non-heart-beating donation ...
... to prevent irreversible blindness secondary to ophthalmic artery occlusion. Steroids do not prevent the diagnosis from later ... Vascular-related cutaneous conditions. Hidden categories: *Articles with short description. *Short description is different ...
Although grafting is often used in cosmetic surgery, it is also used in other surgery. Grafts may be taken from one area of the ... Vascular surgery ICD-9-CM V3 38-39, ICD-10-PCS 03-6 ... Left atrial appendage occlusion. *Cardiotomy. *Heart ... grafts - may be severed pieces of tissue cut from the same (or different) body or flaps of tissue still partly connected to the ... Alternatively, grafts may be from other persons, cadavers, or animals.. *insertion of prosthetic parts when needed. Pins or ...
Among them was an open repair of an atrial septal defect using hypothermia, inflow occlusion and direct vision in a 5-year old ... One of the more commonly known cardiac surgery procedures is the coronary artery bypass graft (CABG), also known as "bypass ... Cardiac surgery training may be combined with thoracic surgery and / or vascular surgery and called cardiovascular (CV) / ... 2002). "Cognitive outcome after off-pump and on-pump coronary artery bypass graft surgery: a randomized trial". JAMA. 287 (11 ...
Faxon, D. P. (1 June 2004). "Atherosclerotic Vascular Disease Conference: Executive Summary: Atherosclerotic Vascular Disease ... Coronary artery bypass grafting (CABG). Medications[edit]. *Statins, which reduce cholesterol, reduce the risk of coronary ... A more severe form is chronic total occlusion (CTO) when a coronary artery is completely obstructed for more than 3 months.[52] ... Deb, S; Wijeysundera, HC; Ko, DT; Tsubota, H; Hill, S; Fremes, SE (20 November 2013). "Coronary artery bypass graft surgery vs ...
... the weakened section of the vessel may be replaced by a bypass graft that is sutured at the vascular stumps. Instead of sewing ... "History of endovascular endosaccular occlusion of brain aneurysms: 1965-1990". Interventional Neuroradiology. 13 (3): 217-24. ... "European Journal of Vascular and Endovascular Surgery. 27 (4): 385-88. doi:10.1016/j.ejvs.2004.01.001. PMID 15015188.. ... "Case Reports in Vascular Medicine. 2013: 452317. doi:10.1155/2013/452317. PMC 3705747. PMID 23864981.. ...
... treatment for atherosclerosis and be more prone to restenosis relative to vascular bypass or coronary artery bypass grafting.[3 ... A small vessel diameter, the presence of posterior calcification, occlusion, hematoma, or a bypass origin[clarification needed] ... Access to the vascular system is typically gained percutaneously (through the skin, without a large surgical incision). An ... Angioplasty requires an access vessel, typically the femoral or radial artery or femoral vein, to permit access to the vascular ...
Prior to issuing platelets to the recipient, they may be irradiated to prevent transfusion-associated graft versus host disease ... Wagner DD, Burger PC (December 2003). "Platelets in inflammation and thrombosis". Arteriosclerosis, Thrombosis, and Vascular ... These agonists induce platelet adhesion, activation and aggregation leading to rapid occlusion of the aperture and cessation of ... and vascular endothelial growth factor. Local application of these factors in increased concentrations through Platelet-rich ...
Prior to issuing platelets to the recipient, they may be irradiated to prevent transfusion-associated graft versus host disease ... These agonists induce platelet adhesion, activation and aggregation leading to rapid occlusion of the aperture and cessation of ... and vascular endothelial growth factor. Local application of these factors in increased concentrations through Platelet-rich ...
Corneal transplant surgery may be difficult due to the peripheral thinning of the cornea, even with large and off-center grafts ... Ocular ischemic syndrome / Central retinal vein occlusion. *Central retinal artery occlusion. *Branch retinal artery occlusion ... However, if there is not enough normal tissue present, then attaching the graft is difficult. New surgical techniques are in ...
In addition to initial RSI, it may also be necessary to adjust the occlusion (bite) to prevent excessive force on teeth that ... Systemic disease may develop because the gums are very vascular (have a good blood supply). The blood stream carries these ... as well as guided tissue regeneration and bone grafting. The goal of periodontal surgery is access for definitive calculus ... and Vascular Biology. 21 (11): 1816-22. doi:10.1161/hq1101.097803. PMID 11701471. Elter JR, Champagne CM, Offenbacher S, Beck ...
The dermis contains two vascular networks that run parallel to the skin surface-one superficial and one deep plexus-which are ... Graft-versus-host disease Griscelli syndrome Hyper-IgE syndrome (Buckley syndrome, Job syndrome) Immunodeficiency with hyper- ... Narcotic dermopathy Occlusion miliaria Painful fat herniation (painful piezogenic pedal papules, piezogenic papules) Peat fire ... vascular rosacea) Excoriated acne (acne excoriée des jeunes filles, Picker's acne) Glandular rosacea Gnathophyma Gram-negative ...
Moreno, PR; Sanz, J; Fuster, V (Jun 2009). "Promoting mechanisms of vascular health: circulating progenitor cells, angiogenesis ... and resistance to atherothrombosis The first demonstration of the role played by platelets in CABG occlusion and prevention by ... "Effect of Dipyridamole and Aspirin on Late Vein-Graft Patency after Coronary Bypass Operations". New England Journal of ... Mechanisms leading to myocardial infarction: insights from studies of vascular biology". Circulation. 90 (4): 2126-46. doi: ...
... in a mutually protected occlusion, help to protect the anterior teeth and the vertical dimension of occlusion and, when missing ... vestibular extensions with or without soft tissue grafting. Edentulism affects approximately 158 million people globally as of ... found significant differences between edentulous and dentate individuals with respect to rates of atherosclerotic vascular ... When there are no teeth present in the mouth, the natural vertical dimension of occlusion is lost and the mouth has a tendency ...
... the weakened section of the vessel may be replaced by a bypass graft that is sutured at the vascular stumps. Instead of sewing ... Guglielmi G (September 2007). "History of endovascular endosaccular occlusion of brain aneurysms: 1965-1990". Interventional ... Vascular Ehlers-Danlos Syndrome. 1999 Sep 2 [Updated 2019 Feb 21]. In: Adam MP, Ardinger HH, Pagon RA, et al., editors. ... Vascular Diseases: Surgical & Interventional Therapy. New York, NY: Churchill Livingstone; 1994:823-844. Lumsden AB, Salam TA, ...
Vascular Occlusion, Cardiac Aneurysms), By Raw Material (PTFE, Polyester), And Segment Forecasts, 2019 - 2026 ... Vascular Grafts Market Size, Share & Trends Analysis Report By Product (Peripheral, Endovascular Stent), By Application ( ... 6.6.1 Global Vascular Occlusion Market Estimates And Forecasts, 2014 - 2026 (USD Million). Chapter 7 Vascular Grafts Market: ... Chapter 5 Vascular Grafts Market: Product Estimates & Trend Analysis. 5.1 Definitions & Scope. 5.2 Vascular Grafts Market Share ...
Mesh term Graft Occlusion, Vascular. Browse to parent terms:. Postoperative Complications. Description. Obstruction of flow in ... biological or prosthetic vascular grafts.. Search for this term in our Faculty Database. View this term at the NCBI website ...
Sciatic palsy after total hip arthroplasty associated with vascular graft occlusion. HIP International. 2011 Apr 11;21(1):118- ... Sciatic palsy after total hip arthroplasty associated with vascular graft occlusion. Charles A. Willis-Owen, Toru Nishiwaki, ... Sciatic palsy after total hip arthroplasty associated with vascular graft occlusion. / Willis-Owen, Charles A.; Nishiwaki, Toru ... title = "Sciatic palsy after total hip arthroplasty associated with vascular graft occlusion", ...
The rate of graft failure because of occlusion was 86.7% for β3−/− mice as compared with 5% for WT mice (Figure 2A and 2B). An ... Vascular matrix and vein graft failure. Is the message in the medium? Circulation. 2000;101:221-223. ... arteriovenous graft. CACs. circulating angiogenic cells. TGF-β1. transforming growth factor β1. WT. wild type. ... AVG Occlusion Accelerated in Integrin β3−/− Mice. Integrin β3 is expressed in artery, vein, and heart tissues; there was no ...
The mandrel has an outer surface corresponding to the inner profile of the occlusion device. A base layer of a biocompatible ... An apparatus and method for making an occlusion device for occluding a body vessel. The apparatus and method include providing ... Coated vascular grafts and methods of use. US6994092 *. 15 Ago 2003. 7 Feb 2006. Ev3 Sunnyvale, Inc.. Device for containing ... Occlusion device with stranded wire support arms. US6206931 *. 22 Ago 1997. 27 Mar 2001. Cook Incorporated. Graft prosthesis ...
A vascular tubular graft of a woven fabric with a single velour outside (external) surface and a smooth interior surface, said ... Perfusion-occlusion apparatus. US6171334. 17 Jun 1998. 9 Jan 2001. Advanced Cardiovascular Systems, Inc.. Expandable stent and ... This invention is directed to vascular grafts of synthetic fibers. Vascular grafts (prothesis) are currently used to replace ... self-supporting woven vascular graft. US5282847 *. 15 Jul 1992. 1 Feb 1994. Medtronic, Inc.. Prosthetic vascular grafts with a ...
Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The ... Silicon micro machined occlusion implant. US5860998 *. Nov 25, 1996. Jan 19, 1999. C. R. Bard, Inc.. Deployment device for ... Woven vascular graft. US4907336 *. Sep 9, 1988. Mar 13, 1990. Cook Incorporated. Method of making an endovascular stent and ... Expandable supportive endoluminal grafts. US5733325 *. May 6, 1996. Mar 31, 1998. C. R. Bard, Inc.. Non-migrating vascular ...
Vascular graft occlusion * 1/887 (0.11%) 0/445 (0.00%) Metabolism and nutrition disorders ...
A collapsible medical device and associated method for grafting a lumen of selected organs and vessels, wherein the medical ... Covered self-expanding vascular occlusion device. US5928248. 25 Feb 1998. 27 Jul 1999. Biosense, Inc.. Guided deployment of ... Thinly woven flexible graft. US5713948. 19 Jul 1995. 3 Feb 1998. Uflacker; Renan. Adjustable and retrievable graft and graft ... Adjustable and retrievable graft and graft delivery system for stent-graft system and methods of implantation. ...
Vascular graft occlusion * # participants affected / at risk 1/887 (0.11%) 0/445 (0.00%) ...
Arterio-Venous Fistula or Graft. *Prior upper extremity vascular manipulation resulting in anatomical changes ... Radial Artery Spasm Leading to Occlusion in Patients Undergoing Coronary Angiogram Via Radial Access. The safety and scientific ... Radial artery occlusion (RAO) is a frequent complication of radial artery cannulation. In the perioperative period, rates of ... Radial artery occlusion can be documented by an abnormal Barbeaus test , visible obstruction on two-dimensional ultrasound or ...
Vascular occlusion methods, systems and devices. WO2005070302A1. 21. Jan. 2005. 4. Aug. 2005. Cook Incorporated. Implantable ... Such medical graft products comprise an elongate graft body of a remodelable matrix material, the elongate graft body including ... graft lumen 92 to allow communication between opposing sides of a graft body exterior surface 94. Graft body 91 also has ... Methods for modifying vascular vessel walls. US20070198059 *. 31. Jan. 2007. 23. Aug. 2007. Patel Umesh H. Fistula grafts and ...
Vascular graft occlusion * 1 28/897 (3.12%) 29. 1/903 (0.11%) 1. ... Total Occlusion (per patient) [1] Measure Type: Number. Unit of ... The impact of a second arterial graft on 5-year outcomes after coronary artery bypass grafting in the Synergy Between ... Coronary Artery By-pass Graft (CABG... Percutaneous coronary intervention ... Arm/Group Description: Coronary Artery By-pass ... Coronary Artery By-pass Graft (CABG... Percutaneous coronary intervention ... Arm/Group Description: Coronary Artery By-pass ...
Overview This report on the vascular graft market analyzes the current and future scenario of the global market. ... vascular occlusion; renal failure, and others). The market segments have been extensively analyzed based on prevalence of the ... the market has been segmented into endovascular stent graft, peripheral vascular graft, hemodialysis access graft, bypass graft ... Terumo Company), and others.The global vascular graft market has been segmented as follows: Global Vascular graft Market ...
The Global Man-made Vascular Graft Market report 2018 covers every single key parameter, for example, piece of the overall ... Vascular occlusion. There are 15 Chapters to deeply display the global Man-made Vascular Graft market. ... to analyze the top manufacturers of Man-made Vascular Graft, with sales, revenue, and price of Man-made Vascular Graft, in 2016 ... Man-made Vascular Graft Market Consumption by Industry Analysis 2018 and Forecast to 2023 by Type, Region and Applications. ...
The global vascular grafts market is set to witness rapid growth on account of increasing incidence of vascular disorders. This ... Bypass Graft, Peripheral Vascular Graft), By Application (Coronary Artery Disease, Vascular Occlusion, Renal Failure), By ... The other major roadblock is the fear of vascular graft infection. Though rare, the possibility of occurrence of vascular graft ... "Vascular Grafts Market Size, Share and Global Trend By Product Type (Endovascular Stent Graft, Hemodialysis Access Graft, ...
4.6 Chronic Total Occlusion (CTO) Devices. 4.7 Aortic Stents. 4.8 Synthetic Surgical Grafts. 4.9 Embolic Protection Devices. ... 4 Global Peripheral Vascular Devices Market, by Segments. 4.1 Overview. 4.2 Peripheral Vascular Stents. 4.3 Peripheral ... 5 Global Peripheral Vascular Devices Market, by Geography. 5.1 Overview. 5.2 Comparative Analysis: Peripheral Vascular Devices ... 1.1 Market Snapshot: Global Peripheral Vascular Devices Market (2011 & 2018). 1.2 Global Peripheral Vascular Devices Market, by ...
However, post-procedure vein graft restenosis impedes its effectiveness and often leads to a high morbidity and mortality, and ... Coronary artery bypass grafting using autologous saphenous veins is a standard surgical therapy for coronary artery diseases. ... Neointimal hyperplasia is a major cause of vein graft occlusion, and is characterized by an imbalance between vascular smooth ... Nogo-B, recognized as a vascular protective factor, has been shown to reduce neointimal thickening in graft veins, but its ...
Conclusions- During saphenous vein graft interventions, particulate retrieved with a vascular filtering device or an occlusion ... Vascular filtering devices may offer superiority over occlusion devices in ease of use, patient tolerance, visualization, and ... Novel approaches to embolic protection, specifically vascular filtering rather than occlusion, have been hampered by the notion ... Embolic Protection With Filtering or Occlusion Balloons During Saphenous Vein Graft Stenting Retrieves Identical Volumes and ...
This research report categorizes the global man-made vascular graft market by companies, region, type and end-use industry. It ... The report gives the research-based overview of on Global Man-made Vascular Graft Market 2019 size, industry status and ... Vascular occlusion. Key Stakeholders of Man-made Vascular Graft Market:. Getinge. Bard PV. Terumo. W. L. Gore. JUNKEN MEDICAL. ... Polyester Man-made Vascular Graft. PTFE Man-made Vascular Graft. Segmentation by Main Application for Man-made Vascular Graft ...
The graft includes: 1) an anchor system that forms an arc at one end of the conduits; and 2) a body element coupled to the ... In particular embodiments, portions of the graft are either self-expandable or balloon-expandable. In still other embodiments, ... An apparatus is provided that includes a graft for coupling two vascular conduits within a patient. ... The graft includes a hemodynamic profile, which reduces scarring or occlusion-type complications that would otherwise arise. In ...
Is transfusion associated with graft occlusion after cardiac operations? Engoren M, Schwann TA, Jewell E, Neill S, Benedict P, ... Impact on early and late mortality after blood transfusion in coronary artery bypass graft surgery. Santos AA, Sousa AG, Thomé ... Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Koch CG, Li L, Duncan AI, ... Blood transfusion for lower extremity bypass is associated with increased wound infection and graft thrombosis. Tan TW, Farber ...
0055] vascular occlusion in peripheral arterial disease; and [0056] venous thromboembolic disease following surgery, during ... they are then transplanted or grafted back into a subject to be treated. The cells once introduced into the body can produce ... vWF is synthesized by vascular endothelial cells and megakaryocytes and circulates in blood as a series of multimers containing ... 0062] The methods of the present invention also be useful in the treatment of vascular syndromes and myeloproliferative ...
MLLs can occur in patients with multiple traumas, multiple vascular injuries, and complex skeletal injury. Vascular surgeons ... Extensive debridement was performed, and the defect was covered with a skin graft. ... Full text: Available Index: WPRIM (Western Pacific) Journal: Vascular Specialist International Year: 2020 Type: Article ... Full text: Available Index: WPRIM (Western Pacific) Journal: Vascular Specialist International Year: 2020 Type: Article ...
Peripheral Vascular Graft, Hemodialysis Access Graft), Application (Coronary Artery Disease, Aneurysm, Vascular Occlusion, and ... Vascular Graft Market report categorizes the global market by Product (Endovascular Stent Graft, ... Vascular Graft Market (Product - Endovascular Stent Graft, Peripheral Vascular Graft, Hemodialysis Access Graft, and Bypass ... Vascular Graft Market Segmentation by Product - Endovascular Stent Graft, Peripheral Vascular Graft, Hemodialysis Access Graft ...
Method and composition for treating vascular graft occlusion. US5654267 *. 30 Nov 1994. 5 Ago 1997. La Jolla Cancer Research ... An example of such an approach is the induction of endothelial cell growth on a prosthetic blood vessel or vascular graft, ... The polypeptide fragment of claim 1 coupled to and forming part of a vascular graft. ... The polypeptide fragment of claim 12 coupled to and forming part of a vascular graft. ...
Graft Occlusion, Vascular / etiology * Graft Occlusion, Vascular / physiopathology * Graft Occlusion, Vascular / prevention & ... Purpose: To explore the safety and efficacy of PRT-201 applied to the outflow vein of a newly created arteriovenous graft (AVG ... Application of human type I pancreatic elastase (PRT-201) to the venous anastomosis of arteriovenous grafts in patients with ... applied to the graft-vein anastomosis and adjacent outflow vein immediately after AVG placement. The primary outcome measure ...
Graft Occlusion, Vascular / epidemiology. Humans. Life Tables. Popliteal Artery*. Risk Factors. Survival Rate. Thromboembolism ... Next Document: Occlusion of the brachial artery by thrombus dislodged from a traumatic aneurysm of the anterior hum.... ... Title: Journal of vascular surgery Volume: 13 ISSN: 0741-5214 ISO Abbreviation: J. Vasc. Surg. Publication Date: 1991 Mar ... When reconstruction of a popliteal aneurysm was performed, graft patency and foot salvage were 64% and 95% at 10 years, ...
... in vascular limb injuries is the graft material of choice. Denatured saphenous vein homograft (DSVH), thanks to its ... Graft Occlusion, Vascular / etiology. Graft Survival. Humans. Leg Injuries / surgery*. Male. Middle Aged. Necrosis. Popliteal ... OBJECTIVES: Autologous saphenous vein (ASV) for arterial reconstruction, in vascular limb injuries is the graft material of ... RESULTS: Four patients had graft thrombosis at the first postoperative week and were submitted to the replacement of the graft ...
The present technique also enhances shape-making capability, for example, of bifurcated vascular grafts, which feature a common ... 14a is an end-on view of a vascular graft showing that the present vascular graft may be provided with a pair of flaps 220, ... This plug continues to grow, resulting in occlusion of the graft. If the graft is not immediately occluded the plug functions ... vascular grafts). Accordingly, a review of the vascular graft art is appropriate. ...
  • Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. (google.com)
  • The present invention relates generally to a device and minimally invasive procedure for treating a localized abnormal dilation of a lumen and more particularly, the present invention relates to a low profile stent suitable for use as a synthetic graft for the non-surgical treatment of an aneurysm, fistula, legion or the like in certain blood vessels and internal organs. (google.com.au)
  • The endovascular stent graft segment dominated the global vascular graft market accounting for the share of 41.0% in 2015 as these devices are mostly utilized by the vascular surgeons for abnormal aortic disorders or aneurysm caused due to cardiovascular disorders or diabetes, and smoking. (transparencymarketresearch.com)
  • When reconstruction of a popliteal aneurysm was performed, graft patency and foot salvage were 64% and 95% at 10 years, respectively. (biomedsearch.com)
  • Occlusion of the brachial artery by thrombus dislodged from a traumatic aneurysm of the anterior hum. (biomedsearch.com)
  • Whether you are seeking treatment for an aneurysm, arterial disease or lymphedema, you are in good hands with our vascular specialists and surgeons, who are nationally recognized for their expert care. (hawaiipacifichealth.org)
  • EXCLUDER®, Endurant®, and AneuRx®) used for abdominal aortic aneurysm (AAA) treatment have limb thrombotic occlusion risks of up to 7.2%, which appears to be low, but they usually require further intervention to resolve ischemic symptoms. (rsc.org)
  • It results from idiopathic inflammation of the artery wall, causes uniform vascular stenosis, dilatation and aneurysm in 25%, and/or thrombosis. (clinicaladvisor.com)
  • We describe what we believe to be a case of sciatic nerve ischemia due to intra-operative arterial occlusion, and we discuss the vascular anatomy which may have contributed. (elsevier.com)
  • These people are at high risk of arterial occlusion, and are candidates for peripheral vascular bypass surgery. (surgeryencyclopedia.com)
  • African-Americans are at greater risk for arterial occlusion than other racial groups in the United States. (surgeryencyclopedia.com)
  • Management of acute arterial occlusion has remained as a challenge for vascular specialists. (scirp.org)
  • Acute arterial occlusion leading to ischemia can be the result of an embolus from a distant source lodging into a more distal vessel, acute thrombosis of a previously patent artery, or a stent/graft, and dissection of or direct trauma to an artery. (scirp.org)
  • The level of arterial occlusion influences location of symptoms. (merckmanuals.com)
  • ConclusionsThe present meta-analysis revealed that, compared to PTS, PTA may provide increased assisted primary patency for endovascular treatment of central vein stenosis or occlusion in patients undergoing hemodialysis.Level of EvidenceLevel 3a. (medworm.com)
  • To determine the efficacy of antiplatelet therapy and oral anticoagulants in maintaining graft patency and preventing ischemic complications in patients after infrainguinal bypass surgery. (york.ac.uk)
  • Doty, et al, have reported on their experience of SVC bypass using the spiral vein graft and demonstrated excellent long-term patency rates (87.5% patency at a mean of 10.9 years) [3]. (ctsnet.org)
  • percutaneous coronary intervention The left internal mammary or thoracic arterial (LIMA) graft confers substantial advantages in terms of long-term patency and survival benefit in patients undergoing coronary artery bypass grafting surgery (CABG). (invasivecardiology.com)
  • 10,11 More recently, the case in favor of LIMA side-branch occlusion has been advanced by demonstration of myocardial ischemia reversal with termination of side-branch patency. (invasivecardiology.com)
  • 12,13 We report a novel approach to LIMA side-branch occlusion, and demonstrate continued LIMA graft patency after a 2-year follow-up period. (invasivecardiology.com)
  • The Scandinavian PROPATEN® Trial - 1-year patency of PTFE vascular prostheses with heparin-bonded luminal surfaces compared to ordinary pure PTFE vascular prostheses - a randomized clinical controlled multi-centre trial. (goremedical.com)
  • We present a nanopolyplex (NP) approach that efficiently delivers a mitogen-activated protein kinase (MAPK)-activated protein (MAPKAP) kinase 2 inhibitory peptide (MK2i) to graft tissue to improve long-term patency by inhibiting pathways that initiate IH. (sciencemag.org)
  • However, almost half of saphenous vein grafts fail within 18 months owing to intimal hyperplasia (IH) ( 1 ), and no current therapeutic approaches inhibit IH and improve graft patency in humans. (sciencemag.org)
  • 4 The long-term clinical outcome after surgery is dependent on the patency of the bypass grafts and the progression of native coronary artery disease. (appliedradiology.com)
  • 8 Benefits of on-pump CABG are that it is less technically demanding, permits more grafts to be constructed per procedure, and, possibly, has better long-term graft patency. (appliedradiology.com)
  • Objective- Neointima formation is associated with stenosis and subsequent thrombosis in arteriovenous grafts (AVGs). (ahajournals.org)
  • This invention relates to an apparatus and method for cleaning diseased vein grafts and other vessels in which the plaque forming the stenosis therein is relatively soft. (google.co.uk)
  • Both the anatomical repair of malfunctioning blood vessels and/or their replacement by grafting autologous blood-conduits are only partially successful: a large percentage (up to 30%) of all angioplasty as well as (coronary) bypass procedures eventually fail mainly due to re-stenosis. (springer.com)
  • 10-12 The introduction of 64-slice MDCT and dual-source CT permitted improved temporal resolution (up to 83 msec) and spatial resolution (0.4 × 0.4 × 0.4 mm 3 ) and reduction of both cardiac and respiratory motion, leading to improved assessment of graft stenosis and occlusion. (appliedradiology.com)
  • 0001] The present invention relates generally to the field of blood function and thrombosis and to methods and products useful in the treatment of thrombotic and vascular disorders. (freepatentsonline.com)
  • The result can be artery occlusion or blood clotting--detrimental conditions called hyperplasia and thrombosis, respectively. (eurekalert.org)
  • By substantially reducing acute graft thrombosis within hours after implantation, the CBAS Heparin Surface on the GORE® PROPATEN® Vascular Graft provides clinical benefits that standard ePTFE grafts do not. (goremedical.com)
  • Denatured venous homograft as an arterial substitute in civilian vascular injuries. (biomedsearch.com)
  • Vascular surgery is the treatment of surgery on diagnosed patients with diseases of the arterial, venous, and lymphatic systems (excluding the intracranial and coronary arteries). (encyclopedia.com)
  • Using a standard 2-stage venous cannulae, a spiral vein graft was constructed using running 7-0 prolene suture, exchanging suture with each completed turn (Figures 5 and 6) . (ctsnet.org)
  • Straub's unique team approach means that vascular surgeons work closely with their colleagues, who are specialists from the departments of cardiology, neurology, and diagnostic and interventional radiology, to care for patients with common vascular diseases, complex illnesses and rare arterial, venous or lymphatic problems. (hawaiipacifichealth.org)
  • Cervicomediastinal vascular injuries are defined as arterial or venous injuries of the neck [carotids, subclavian (including its branches) and the proximal axillary artery], and mediastinum [ascending aorta, aortic arch (including its branches), descending aorta, the pulmonary artery and veins]. (thefreelibrary.com)
  • Based on End-user, the vascular graft market has been segmented into four major categories: hospitals, ambulatory surgical centers, specialty clinics, cardiac catheterization laboratories, and others. (medindia.net)
  • Is transfusion associated with graft occlusion after cardiac operations? (jw.org)
  • Vascular grafts are used by various end users including hospitals, ambulatory surgical centers, specialty clinics, cardiac catheterization laboratories, and others. (transparencymarketresearch.com)
  • The conference is the premier forum for professors, researchers, members from the renowned societies and institutes, young researchers from academia and industry to explore their shared interest in the field of cardiac & vascular medicine. (eventbrite.com)
  • Thus, there is an increasing world-wide demand for permanent cardiovascular prostheses, such as vascular grafts, cardiac assist devices or total artificial hearts. (springer.com)
  • Your doctor at the UPMC Heart and Vascular Institute will use cardiac catheterization and angiography to diagnose CTO. (upmc.com)
  • LeMaitre Vascular, Inc. (researchandmarkets.com)
  • Some of the key players identified by Fortune Business Insights in this market include CryoLife, Vascular Grafts Solutions, Cook Medical, Artegraft, LeMaitre Vascular, and others. (medgadget.com)
  • Endovascular stent grafts dominated the market in 2018 and is expected to be the second fastest-growing segment over the forecast period. (researchandmarkets.com)
  • Increasing prevalence of cardiovascular aneurysms is the leading cause of rise in demand for endovascular stent grafts. (researchandmarkets.com)
  • Global Vascular Graft Market: Segmentation Based on product, the market has been segmented into endovascular stent graft, peripheral vascular graft, hemodialysis access graft, bypass graft, and others. (medindia.net)
  • Vascular surgery involves techniques relating to endovascular surgeries including: balloon angioplasty and/or stenting, aortic and peripheral vascular endovascular stent/graft placement, thrombolysis, and other adjuncts for vascular reconstruction. (encyclopedia.com)
  • Initially, the patient was seen by vascular surgery and an unsuccessful attempt at an endovascular stent placement was performed. (ctsnet.org)
  • The most common condition that requires the use of a vascular graft is ischemia (inadequate blood supply) caused by arteriosclerosis. (medgadget.com)
  • 19 However, rigorous particulate analysis was not performed in that trial, and it is not known whether there may be benefits of an occlusion balloon system (eg, more complete particulate retrieval and prevention of soluble mediators released during intervention) that are being offset by requisite procedural ischemia provoked by occlusion. (ahajournals.org)
  • Given the large caliber of the LIMA side branch (Figure 1), it was felt that this may have been a contributing factor in the relatively poor LIMA-LAD graft development and LAD territory ischemia. (invasivecardiology.com)
  • It is commonly performed due to inadequate blood flow (ischemia) caused by atherosclerosis, as a part of organ transplantation, or for vascular access in hemodialysis. (wikipedia.org)
  • In the legs, bypass grafting is used to treat peripheral vascular disease, acute limb ischemia, aneurysms and trauma. (wikipedia.org)
  • 50% reduction in risk of graft occlusion compared to standard ePTFE in critical limb ischemia (CLI) patients. (goremedical.com)
  • Transradial (TR) approach for PCI has gained widespread popularity secondary to decreased bleeding and reduced vascular access site complications as compared to transfemoral (TF) access. (clinicaltrials.gov)
  • Researchers at the University of Pittsburgh are developing synthetic grafts that mimic the body's own blood vessels to mitigate many of the complications of bypass surgery. (eurekalert.org)
  • Secondary outcome measures were stroke, myocardial infarction, vascular and total mortality, and the composite outcome of stroke, myocardial infarction, vascular mortality and medication-related bleeding complications. (york.ac.uk)
  • 2 In adults, common causes of SBS include unanticipated complications following surgery, cancer, mesenteric vascular disease, and Crohn's disease. (dovepress.com)
  • Platelet adhesion and activation on material surfaces of blood-contacting medical devices and implants, such as stents, vascular grafts, artificial organ implants, and hemodialysis equipment, cause thrombotic and thromboembolic complications, which may need further intervention or induce implant failure and fatal outcomes. (rsc.org)
  • Other end points included procedural outcomes, such as procedural success, bleeding, and vascular complications. (bcs.com)
  • METHODS: From January 2008 through January 2013 our radiological records were searched for cases with post surgical vascular complications treated with endovascular intervention. (minervamedica.it)
  • RESULTS: Twelve patients with graft related complications treated with endovascular intervention were recorded. (minervamedica.it)
  • There were no complications like endoleaks or limb occlusions. (minervamedica.it)
  • CONCLUSION: Endovascular treatment of vascular graft related postsurgical complications is a valuable therapeutic option followed by lower mortality and morbidity rates compared with re-operation. (minervamedica.it)
  • The major segments in the market include peripheral vascular stents, peripheral transluminal angioplasty balloon catheters, PTA guidewires, atherectomy devices, chronic total occlusion devices, aortic stents, synthetic surgical grafts, embolic protection devices and inferior vena cava filters. (finanznachrichten.de)
  • The Medtronic Open Pivot™ Aortic Valved Graft unites a fundamentally different bileaflet heart valve design with leading graft technology for exceptional implantability. (medtronic.com)
  • Unlike other bileaflet valves, which use cavity pivots, the Medtronic Open Pivot Aortic Valved Graft (AVG) has no recesses or cavities in the pivot area where thrombogenesis can occur. (medtronic.com)
  • With no tapers or pleats, the Medtronic Open Pivot Aortic Valved Graft allows for easy anastomosis anywhere on the graft. (medtronic.com)
  • A few common diseases affecting the arteries are peripheral vascular disease (PVD), carotid artery disease, and aortic aneurysms (AAA). (encyclopedia.com)
  • Used when patient cannot tolerate a more invasive and higher risk aorto-bifem, or when removing an infected aortic graft such as an EVAR device. (wikipedia.org)
  • Department of Vascular Surgery, Civic Hospital Benfratelli of Palermo, Italy. (biomedsearch.com)
  • Vascular surgery is indicated when a patient has vascular disease that cannot be treated by less invasive, nonsurgical treatments. (encyclopedia.com)
  • The purpose of vascular surgery is to treat vascular diseases, which are diseases of the arteries and veins. (encyclopedia.com)
  • Dr. Thomas J Fogarty, MD is a Doctor primarily located in Mountain View, CA . His specialties include Thoracic Surgery (Cardiothoracic Vascular Surgery) , Surgery and Vascular Surgery . (vitals.com)
  • A multicenter, multinational study reported an increase in the risk of graft closure (p=0.035) in patients undergoing primary CABG surgery treated with aprotinin versus placebo. (drugs.com)
  • Angiographic outcomes of radial artery versus saphenous vein in coronary artery bypass graft surgery: a meta-analysis of randomized controlled trials. (springer.com)
  • During bypass surgery in replacing diseased vessels in the heart, it is conventional to utilize the saphenous veins in the body of the same person and utilizing portions of those veins to create bypass grafts in diseased vessels in the heart. (google.co.uk)
  • Advancements in graft materials and surgery techniques such as off-pump CABG surgery are driving the growth of vascular grafts market. (coherentmarketinsights.com)
  • Data on initiation and length of therapy, length of follow-up, indication of surgery, type of bypass, and graft material were abstracted for all included studies. (york.ac.uk)
  • Platelet activation contributes to graft occlusion after bypass surgery. (ebscohost.com)
  • Common bypass sites include the heart (coronary artery bypass surgery) to treat coronary artery disease, and the legs, where lower extremity bypass surgery is used to treat peripheral vascular disease. (wikipedia.org)
  • Vascular surgery is a sub-speciality of surgical procedures where vascular diseases are treated by medical therapy and other minimally invasive procedures. (eventbrite.com)
  • Prevention of graft occlusion in patients following aortocoronary by-pass surgery. (mims.com)
  • Peripheral vascular bypass surgery is performed to restore blood flow (revascularization) in the veins and arteries of people who have peripheral arterial disease (PAD), a form of peripheral vascular disease (PVD). (surgeryencyclopedia.com)
  • Peripheral vascular bypass surgery is a treatment option when PAD affects the legs and feet. (surgeryencyclopedia.com)
  • Vascular occlusion is used to reduce blood loss during liver resection surgery. (essentialevidenceplus.com)
  • European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437. (goremedical.com)
  • European Journal of Vascular & Endovascular Surgery 2011;41(5):668-673. (goremedical.com)
  • Annals of Vascular Surgery 2018;49:295-303. (goremedical.com)
  • Coronary artery bypass graft (CABG) surgery is one of the most commonly performed surgical procedures. (appliedradiology.com)
  • Our parent vascular surgery department in Durban pioneered the concept of a dedicated metropolitan vascular trauma service over three decades ago in response to the complex nature of these injuries and their relative rarity. (thefreelibrary.com)
  • The vascular surgery unit was initiated in January 2013, with a single full-time certified vascular surgeon. (thefreelibrary.com)
  • Currently, vascular trauma cases are exclusively co-managed by the trauma and vascular surgery units. (thefreelibrary.com)
  • The Midwest with sales (volume), revenue (value), market share and growth rate of Peripheral Vascular Graft in these regions, from 2012 to 2022 (forecast). (reportsnreports.com)
  • Coronary Artery By-pass Graft (CABG. (clinicaltrials.gov)
  • Saphenous vein (SV) is a common graft being used in coronary artery bypass grafting (CABG). (springer.com)
  • Before placement of the arterial line, it should be ensured that a radial artery graft will not be used for CABG. (medscape.com)
  • In recent years, new surgical techniques permit CABG without a heart-lung machine or cardioplegia (off-pump grafting). (appliedradiology.com)
  • The Global Man-made Vascular Graft Market report 2018 covers every single key parameter, for example, piece of the overall industry, income age, new items or showcasing techniques of the opposition, most recent R&D, and market master remarks, alongside the contact data. (medgadget.com)
  • While North America continues to hold the largest share in the global vascular grafts market, Asia-Pacific is slated to register a relatively higher CAGR between 2018 and 2026. (medgadget.com)
  • Research and Markets (http://www.researchandmarkets.com/research/26bk5r/peripheral) has announced the addition of the "Global Peripheral Vascular Devices Market Report 2013 - 2018" report to their offering. (finanznachrichten.de)
  • The global market for peripheral vascular devices was valued at USD 4,802.6 million in 2011, with an expected CAGR of 7.1% from 2012 to 2018. (finanznachrichten.de)
  • Vascular graft or bypass is a widely accepted and recommended surgical procedure. (medgadget.com)
  • Coronary artery bypass grafting using autologous saphenous veins is a standard surgical therapy for coronary artery diseases. (nih.gov)
  • Surgical Treatment of Acute Thoracic Stent-Graft Occlusion. (annals.org)
  • Blood flow is redirected from one place to another by introducing a graft with the help of surgical reconstruction process. (coherentmarketinsights.com)
  • Vascular grafts are majorly used in treatment of cardiovascular diseases by surgical procedures such as bypass grafting. (coherentmarketinsights.com)
  • We are dedicated to the prevention, diagnosis and treatment - both non-surgical and surgical - of vascular disease . (mercydesmoines.org)
  • A vascular bypass is a surgical procedure performed to redirect blood flow from one area to another by reconnecting blood vessels. (wikipedia.org)
  • A surgeon sews the graft to the source and target vessels by hand using surgical suture, creating a surgical anastomosis. (wikipedia.org)
  • Vascular diseases can sometimes be treated by non-surgical procedures. (eventbrite.com)
  • A peripheral vascular bypass, also called a lower extremity bypass, is the surgical rerouting of blood flow around an obstructed artery that supplies blood to the legs and feet. (surgeryencyclopedia.com)
  • 1,2) The operative management of cervicomediastinal vascular trauma is challenging as surgical access is difficult, and loss of control can result in rapid exsanguination. (thefreelibrary.com)
  • An apparatus and method for making an occlusion device for occluding a body vessel. (google.es)
  • Alternatively, the graft may be used as a bypass around a diseased vessel. (google.ca)
  • This vessel trauma can cause activation of coagulation system and formation of clot and subsequently the occlusion of radial artery. (clinicaltrials.gov)
  • Development of RAO has been related to the severity of the lesion suffered by the artery during the procedure thus, radial spasm which supposedly occurs secondary to vessel trauma may be associated with subsequent occlusion of radial artery. (clinicaltrials.gov)
  • Both occlusion balloons and filters have the potential to inflict damage to the vessel wall during deployment, use, or retrieval. (ahajournals.org)
  • A graft vessel preparation device and a method for using the graft vessel preparation device is provided. (google.com.au)
  • The graft vessel preparation device establishes and maintains a critical dimension on a graft vessel which corresponds to a dimension of an anastomosis site on a target vessel. (google.com.au)
  • One example of a graft vessel preparation device which prepares a graft vessel for a vascular anastomosis procedure includes a parallelogram linkage, a first spreader arm and a second spreader arm. (google.com.au)
  • The spreader arms are configured in order to allow the placement of an end of a graft vessel over the spreader arms. (google.com.au)
  • The spreader arms are also configured to separate within an interior of the graft vessel once the graft vessel is placed over the spreader arms in order to establish a critical dimension. (google.com.au)
  • The critical dimension locator allows for precise grafting of the graft vessel to a target vessel during the vascular anastomosis procedure. (google.com.au)
  • a clamp configured to coordinate with both the spreader and the critical dimension locator in order to fix the critical dimension on the graft vessel. (google.com.au)
  • 4. A graft vessel preparation device as recited in claim 3 , wherein the clamp rotatably attaches to the two base plates. (google.com.au)
  • a spring attached to one of the two base plates and fixed to a second surface, whereby a tensile force of the spring places tension on the graft vessel preparation device in order to rotate the extension link. (google.com.au)
  • 6. A graft vessel preparation device as recited in claim 5 , wherein the extension link rotates a given angle. (google.com.au)
  • 8. A graft vessel preparation device as recited in claim 1 , wherein the critical dimension corresponds to a length of an anastomosis and allows proper grafting of the graft vessel to a coronary vessel during a vascular anastomosis procedure. (google.com.au)
  • a spring attached to both the first end of the first spreader arm and the first end of the second spreader arm such that the first spreader arm is biased apart from the second spreader arm to stretch an end portion of the graft vessel. (google.com.au)
  • 10. A graft vessel preparation device as recited in claim 9 , wherein the first spreader arm and the second spreader arm have second ends configured to receive the end portion of the graft vessel. (google.com.au)
  • a second half that attaches to the first half, where the first half and the second half are configured to receive both the graft vessel and the spreader. (google.com.au)
  • The compressive force of conventional clamps and clips relies on the strength of a spring mechanism as exemplified by intracranial aneurism clips with softened spring action, which are used for temporary occlusion of blood vessels, or on the surgeon's sense of feel that the vessel has been closed when using a hemostat-like clamp. (google.com)
  • Because the saphenous vein graft during the bypass procedure is expanded and reimplanted, much of the vessel becomes fibrose and dies. (google.co.uk)
  • In general, it is an object of the present invention to provide an apparatus and method for cleaning diseased vein grafts and other vessels in the body including soft substances therein which create stenoses in the vessel. (google.co.uk)
  • Chiu and colleagues ingeniously devised the new method by harvesting autologous saphenous vein, opening the vessel longitudinally, wrapping it in spiral fashion around a temporary tubular stent such as a chest tube, and then running a monofilament suture to construct the tube graft. (ctsnet.org)
  • A substitute vessel or graft must be used in bypass surgeries to reroute the blood. (surgeryencyclopedia.com)
  • A synthetic graft may be used if the patient's saphenous vein is not healthy or long enough, or if the vessel to be bypassed is a larger artery that cannot be replaced by a smaller vein. (surgeryencyclopedia.com)
  • 1. an anastomosis connecting the end of an artery and that of some other vessel, either directly or with a synthetic graft. (thefreedictionary.com)
  • A vascular bypass is often created to serve as an access point to the circulatory system for hemodialysis. (wikipedia.org)
  • Following consultation with the patient and a cardiothoracic surgeon, the decision was taken to attempt side-branch occlusion with subsequent angioplasty and stenting to the LIMA-LAD graft insertion site. (invasivecardiology.com)
  • The UPMC Heart and Vascular Institute is one of a few centers with the expertise in performing angioplasty to treat CTO. (upmc.com)
  • In fact, the UPMC Heart and Vascular Institute is the only center in western Pennsylvania that offers a program dedicated to angioplasty treatment for CTO . (upmc.com)
  • 10. The method of repairing an artery comprising connecting the graft of claim 1 to an artery. (google.ca)
  • Vascular grafts (prothesis) are currently used to replace certain diseased arteries by joining e.g., by sewing the ends of the vascular tubular grafts to the remaining portions of the artery e.g., human artery. (google.ca)
  • Operations for this purpose are commonly done by surgeons who first remove the diseased portion of the artery, e.g., blocked by a clot, and then implant the graft in its place. (google.ca)
  • In this study the investigators intend to find the association of radial artery spasm with the future development of radial artery occlusion in patients who undergo PCI via radial access. (clinicaltrials.gov)
  • It's hypothesized that there might be vascular endothelial damage during catheter manipulation when patients have RAS which can activate the coagulation cascade and can result in radial artery occlusion. (clinicaltrials.gov)
  • Radial artery occlusion (RAO) is a frequent complication of radial artery cannulation. (clinicaltrials.gov)
  • Radial artery occlusion can be documented by an abnormal Barbeau's test , visible obstruction on two-dimensional ultrasound or absence of Doppler flow signal distal to the puncture site. (clinicaltrials.gov)
  • Radial artery occlusion is usually clinically quiescent and doesn't require any intervention secondary to dual blood supply of the arm. (clinicaltrials.gov)
  • Computed tomography showed bilateral popliteal artery occlusion with large hematoma on both legs . (bvsalud.org)
  • Bypass graft segment is projected to grow with a second highest CAGR between 2016 and 2024 due to increase in number of incidences of coronary artery diseases caused due to increase in obesity and unhealthy food habits. (transparencymarketresearch.com)
  • The primary purpose of a vascular grafts is to act as an artificial conduit for a diseased artery and help to redirect blood flow from one area to another. (researchandmarkets.com)
  • He will use these materials along with computational optimiztion to engineer a graft with compliance similar to a real artery, eliminating compliance mismatch - an important rejection mechanism in currently used grafts. (eurekalert.org)
  • We believe our method of mimicking native artery microstructure and mechanics will result in a successful tissue-engineered graft, and this grant will support trials to perfect both our experimental and computational approach," says Dr. Vande Geest. (eurekalert.org)
  • We report a novel percutaneous therapeutic approach to the management of suspected coronary artery steal syndrome resulting from a large side branch of the left internal mammary artery bypass graft, using a combination of coated and drug-eluting stents. (invasivecardiology.com)
  • Ophthalmologic a€" visual field defect, retinal vein occlusion, retinal artery occlusion Non-arteritic anterior ischemic. (amazonaws.com)
  • Early and late outcome after carotid artery bypass grafting with saphenous vein. (medscape.com)
  • a "DP" bypass - any vascular bypass where the target is the dorsalis pedis artery on the dorsum of the foot. (wikipedia.org)
  • For coronary and peripheral vascular disease, lack of "runoff" to the distal area is also a contraindication because a vascular bypass around one diseased artery to another diseased area does not solve the vascular problem. (wikipedia.org)
  • Just as coronary artery disease can cause a heart attack when plaque blocks the arteries of the heart, or blockage in the carotid artery leading to the brain can cause a stroke, occlusion of the peripheral arteries can create life-threatening conditions. (surgeryencyclopedia.com)
  • Chronic coronary total occlusion (CTO) occurs when a buildup of plaque blocks the coronary artery for more than 90 days, starving your heart of oxygen. (upmc.com)
  • Chronic coronary total occlusion (CTO) occurs when either the left main or right coronary artery - one of the arteries that delivers oxygen-rich blood to your heart - has become completely blocked or occluded for three months or longer. (upmc.com)
  • The CBAS Heparin Surface of a 3 mm diameter GORE® PROPATEN® Vascular Graft (top) remains free of thrombus, while the 3 mm diameter control ePTFE graft (bottom) is covered with thrombus in an acute two-hour in vivo canine carotid artery interposition model. (goremedical.com)
  • Sustained thromboresistant bioactivity with reduced intimal hyperplasia of heparin-bonded PTFE Propaten Graft in a chronic canine femoral artery bypass model. (goremedical.com)
  • Autologous vein grafts are commonly used for coronary and peripheral artery bypass but have a high incidence of intimal hyperplasia (IH) and failure. (sciencemag.org)
  • Such grafts usually are used in connection with arteries which carry large blood volumes e.g., located in the lower body of the human, although it may be used in other parts of the human body. (google.ca)
  • Peripheral vascular disease (PVD) is narrowing of arteries outside the brain and heart. (finanznachrichten.de)
  • Arterial disease is a condition in which blood clots, arteriosclerosis, and other vascular conditions occur in the arteries. (encyclopedia.com)
  • Some vascular conditions occur only in arteries, others occur only in the veins, and some affect both veins and arteries. (encyclopedia.com)
  • Vascular surgeons treat and manage disorders in your veins, arteries and your lymphatic system to ensure blood circulation in your heart and in brain is the best it can be. (vitals.com)
  • When a patient with heart disease is in need of a vascular graft but doesn't have any viable veins or arteries in his or her own body, surgeons can rely on synthetic, tissue-engineering grafts. (eurekalert.org)
  • Vascular grafts are required to replace injured blood vessels, veins, and arteries and to substitute hard blood vessels or valves. (coherentmarketinsights.com)
  • Straub provides state-of-the-art diagnosis and comprehensive treatment of vascular diseases of the circulatory system, which include arteries, veins and lymphatics. (hawaiipacifichealth.org)
  • Arteries can also serve as vascular grafts. (wikipedia.org)
  • Vascular system is composed of blood vessels, especially arteries and veins, which carry blood and lymph throughout the human body. (eventbrite.com)
  • Obstruction of flow in biological or prosthetic vascular grafts. (mcw.edu)
  • Vascular graft has been a prosthetic of choice among the vascular and other cardiovascular surgeons worldwide due to its strong, inert and biocompatible design which also varies in sizes and configurations in order to improve vascular access. (transparencymarketresearch.com)
  • GORE® PROPATEN® Vascular Graft, a leading prosthetic vascular graft for lower extremity revascularization, is specifically designed to reduce the risk of acute graft thrombotic failure. (goremedical.com)
  • With more than 10 years of performance, over 600,000 devices implanted, and over 2,000 limbs studied, the GORE® PROPATEN® Vascular Graft is a leading prosthetic bypass graft solution for proven clinical performance and low cumulative cost of care. (goremedical.com)
  • The GORE® PROPATEN® Vascular Graft is a leading prosthetic bypass graft solution for proven clinical performance and low cumulative cost of care. (goremedical.com)
  • A catheter (10) for removing vascular obstruction(s) is disclosed. (google.ca)
  • The origin of the LIMA graft was selectively engaged using a 6 French (Fr) IMA guide catheter and a PT Graphix Intermediate 0.014 inch guidewire (Boston Scientific Corp., Natick, Massacusetts) was advanced beyond the origin of the LIMA side branch. (invasivecardiology.com)
  • A major complication of percutaneous interventions in degenerated saphenous vein grafts (SVGs) is distal embolization of plaque constituents that results in no-reflow, myocardial infarction, and stroke. (ahajournals.org)
  • Ziad Ali, MD - interventional cardiologist and associate director of translational medicine at the Center for Interventional Vascular Therapy at NewYork-Presbyterian/Columbia, he specializes in percutaneous coronary and peripheral vascular interventions. (newswise.com)
  • We used a novel method of microparticle size assessment to measure volume and characterize individual sizes of particles captured by the PercuSurge GuardWire balloon or a vascular filter during saphenous vein graft stenting. (ahajournals.org)
  • Methods and Results- Braided nitinol filters (average distal pore size 100 μm) were used in 47 saphenous vein grafts in 44 patients. (ahajournals.org)
  • The PercuSurge GuardWire was used in 17 saphenous vein grafts in 16 patients. (ahajournals.org)
  • Conclusions- During saphenous vein graft interventions, particulate retrieved with a vascular filtering device or an occlusion balloon was similar in amount and character. (ahajournals.org)
  • OBJECTIVES: Autologous saphenous vein (ASV) for arterial reconstruction, in vascular limb injuries is the graft material of choice. (biomedsearch.com)
  • Preserved endothelial integrity and nitric oxide synthase in saphenous vein grafts harvested by a "notouch" technique. (springer.com)
  • Rather it has been found that within the implanted saphenous vein grafts, a layer of lipids and other material lie in the inner surface of the graft. (google.co.uk)
  • In the past the procedure has been to perform another bypass procedure utilizing a saphenous vein graft from the other leg of the patient. (google.co.uk)
  • FIG. 1 is a side-elevational view partially in cross section of an apparatus incorporating the present invention for cleaning vein grafts and particularly saphenous vein grafts. (google.co.uk)
  • The saphenous vein graft (SVG) to the circumflex marginal system was occluded at its origin. (invasivecardiology.com)
  • The graft may be a healthy segment of the patient's own saphenous vein (autogenous graft), a vein that runs the entire length of the thigh. (surgeryencyclopedia.com)
  • Man-made Vascular Grafts are used to replace, bypass or maintain function of damaged, occluded or diseased blood vessels in small, medium and large diameter. (medgadget.com)
  • The vascular system is the network of blood vessels that circulate blood to and from the heart and lungs. (encyclopedia.com)
  • Vascular diseases are usually caused by conditions that clog or weaken blood vessels, or damage valves that control the flow of blood in and out of the veins, thus robbing them of vital blood nutrients and oxygen. (encyclopedia.com)
  • Small-diameter vascular grafts, or grafts involving blood vessels with an internal diameter smaller than five millimeters, have much higher failure rates than larger ones," says Dr. Vande Geest. (eurekalert.org)
  • A significant proportion of vascular disease cases involve small-diameter blood vessels, so the demand for viable treatment options is very high. (eurekalert.org)
  • Vascular Grafts are medical devices used to bypass the infected or diseased blood vessels. (coherentmarketinsights.com)
  • The graft is taken from the patient's body and surgically inserted at the required site to bypass the damaged or diseased blood vessels. (coherentmarketinsights.com)
  • Vascular doctors specialize in treating conditions that affect your blood vessels. (hawaiipacifichealth.org)
  • Vascular Biology is a study of the circulatory system that involves the heart and blood vessels. (eventbrite.com)
  • The vascular system is an important part of the body with a huge network of small and large blood vessels, accommodating varying levels of blood flow and pressure throughout the body. (eventbrite.com)
  • Nogo-B, recognized as a vascular protective factor, has been shown to reduce neointimal thickening in graft veins, but its specific mechanism is uncertain. (nih.gov)
  • The vein graft was left on the end of the cannulae and using a parachute technique an end-to-end anastomosis was first created in the distal SVC at the confluence of the right internal jugular and subclavian veins. (ctsnet.org)
  • Combined with this, the rising rate of weight, diabetes, renal impedances, and other ceaseless diseases worldwide will keep the interest for vascular grafts high in the inevitable years. (transparencymarketresearch.com)
  • However, post-procedure vein graft restenosis impedes its effectiveness and often leads to a high morbidity and mortality, and a reduction in the quality of life. (nih.gov)
  • Neointimal hyperplasia is a major cause of vein graft occlusion, and is characterized by an imbalance between vascular smooth muscle cell (VSMC) proliferation and apoptosis. (nih.gov)
  • So far, there have been no optimally effective pharmacological or non-pharmacological interventions for the prevention and treatment of vein graft occlusion. (nih.gov)
  • This study will provide a new clue for gene therapy in the treatment of vein graft failure. (nih.gov)
  • Vein graft failure. (springer.com)
  • Towards the prevention of vein graft failure. (springer.com)
  • However, this latter procedure is particularly dangerous because of the softness of the material within the vein graft which makes it easy to dislodge and create embolic events downstream of the graft. (google.co.uk)
  • There is therefore need for a new and improved graft and method which makes it possible to clean or clear the vein graft while limiting the exposure of the patient to embolic events. (google.co.uk)
  • Following de-airing, inspection revealed the vein graft to be widely patent with no thrill or kinking (Figure 7) . (ctsnet.org)
  • During the early stages of chronic coronary total occlusion (CTO), there may be no symptoms at all. (upmc.com)
  • With the increasing aging population in developed economies such as North America and Europe , the demand for peripheral vascular devices would also increase. (finanznachrichten.de)
  • This report focuses on the man-made vascular graft in the global market, especially in North America, Europe, Asia-Pacific, Latin America, Middle East and Africa . (pharmiweb.com)
  • North America dominated the global vascular graft market in 2015 with a share of 45.0% due to factors such as increasing prevalence of cardiovascular diseases and better healthcare awareness program for diabetes. (transparencymarketresearch.com)
  • Furthermore, technological developments and increasing expenditure by major key players for development of vascular graft are also boosting the growth of the vascular graft market in North America. (transparencymarketresearch.com)
  • Territorially, North America rose prevailing around the same time holding more than 45% of the worldwide vascular grafts market. (transparencymarketresearch.com)
  • Regional segmentation of the vascular grafts market by Coherent Market Insights comprises North America, Europe, Latin America, Asia Pacific, Middle East, and Africa. (coherentmarketinsights.com)
  • What is the global ( North America, Europe, Asia-Pacific, South America, Middle East and Africa ) sales value, production value, consumption value, import and export of Man-made Vascular Graft? (mysmartrend.com)
  • The rising number of cases related to such diseases in both the developed and developing nations is expected to aid the rapid growth of the global vascular grafts market in the forecast period. (medgadget.com)
  • Growth of the global peripheral vascular devices market is fuelled by the rate of population growth globally and the high incidence of peripheral vascular diseases due to increasing aging population. (finanznachrichten.de)
  • The rise in vascular graft usage has been increased due to increase in cardiovascular diseases and diabetes. (transparencymarketresearch.com)
  • Increase in incidence of cardiovascular diseases and peripheral diseases is projected to drive demand for vascular grafts. (researchandmarkets.com)
  • As people age, vascular diseases are very common. (encyclopedia.com)
  • Furthermore, according to the AHA in 2017, around 92 million American adults are suffering from cardiovascular diseases, which is expected to fuel the growth of vascular grafts market. (coherentmarketinsights.com)
  • Factors such as increasing geriatric population, increasing diabetes prevalence leading to heart diseases, and unhealthy lifestyles are expected to increase the prevalence of cardiovascular diseases, in turn boosting the growth of bypass surgeries and vascular grafts market. (coherentmarketinsights.com)
  • Vascular conditions can be caused by diseases that also affect other organs or systems in your body, so our specialists work closely with all your doctors to ensure coordinated care. (hawaiipacifichealth.org)
  • Pali Momi offers advanced detection and treatment of vascular diseases for the people of Central and West Oahu. (hawaiipacifichealth.org)
  • The UC Heart, Lung and Vascular Institute builds upon its nationally known cardiovascular diseases discoveries to make significant contributions to research, education and patient care. (uc.edu)
  • Meanwhile, aneurysum, vascular occlusion and some other diseases are all drive the demand of vascular graft. (mysmartrend.com)
  • Hage ZA, Behbahani M, Amin-Hanjani S, Charbel FT. Carotid bypass for carotid occlusion. (medscape.com)
  • 4-7 Distal protection devices 8-17 have been developed, intended to trap plaque-derived emboli during interventions and prevent embolization into the distal vascular bed. (ahajournals.org)
  • The LIMA to the distal LAD had undergone subtotal occlusion in the 5 days between the initial diagnostic angiogram performed at the referring institution and the current study (Figure 1). (invasivecardiology.com)
  • Dogma in vascular bypass technique says to obtain proximal and distal control. (wikipedia.org)
  • vWF is synthesized by vascular endothelial cells and megakaryocytes and circulates in blood as a series of multimers containing a variable number of ˜500 kDa homodimers. (freepatentsonline.com)
  • Our graft will be endothelialized using blood derived endothelial cells. (eurekalert.org)
  • Callow A.D . (1990) The vascular endothelial cell as a vehicle for gene therapy. (springer.com)
  • The product market segments have been analyzed based on available approved products, cost-effectiveness, and preference for technologies by vascular surgeons and patients. (medindia.net)
  • Vascular surgeons treating multiple traumas should be aware of the diagnostic and management options for MLL. (bvsalud.org)
  • Straub's experienced vascular surgeons care for thousands of patients in Hawaii each year. (hawaiipacifichealth.org)
  • Straub Vascular Lab is accredited and is managed by vascular surgeons and vascular medicine specialists skilled in evaluating vascular disease through the use of diagnostic testing. (hawaiipacifichealth.org)
  • Vascular trauma management had been left up to individual surgeons prior to the development of these two services. (thefreelibrary.com)
  • The unit functions in a closed fashion, and there is a separate vascular trauma roster to ensure that vascular trauma cases are exclusively managed by a dedicated core of vascular trauma surgeons. (thefreelibrary.com)
  • There are different forms of vascular specialities based on diagnosis and therapeutic procedures. (eventbrite.com)
  • The global vascular grafts market size is projected to reach at USD 3.30 billion by 2026 expanding at a CAGR of 6.4%, according to this report. (researchandmarkets.com)
  • If these figures hold true, the global vascular grafts market will exhibit a CAGR of 5.0% between 2016 and 2024. (transparencymarketresearch.com)
  • According to Transparency Market Research (TMR), the worldwide vascular grafts market is conjecture to show a strong CAGR of 5.0% within the forecast period from 2016 to 2024. (transparencymarketresearch.com)
  • In this report, the global Man-made Vascular Graft market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022. (rnrmarketresearch.com)
  • Med en uppdaterad webbläsare kommer du att få en bättre upplevelse på Medtronic webbplats. (medtronic.com)
  • Implanted stent graft were Endurant (Medtronic) bifurcated endoprostheses in three patients and Excluder (Gore) prosthesis in a two cases. (minervamedica.it)
  • In particular embodiments, portions of the graft are either self-expandable or balloon-expandable. (google.com)
  • The coronary stents is segmented on the basis of product Bare Metal Stents (BMS), Drug Eluting Stents (DES) and Bioresorbable Vascular Scaffolds (BVS). (openpr.com)
  • It has not been established that the efficacy of occlusion systems can be matched by newer approaches to embolic protection such as filtering devices, which do not occlude anterograde flow but rather strain the effluent so as to prevent particulate embolization. (ahajournals.org)
  • Embolic protection devices are the fastest growing segment in the total peripheral vascular devices market. (finanznachrichten.de)
  • The use of spiral vein grafting in benign SVC obstruction is superior to either PTFE grafting or nonsurgical interventions such as PTCA or stenting [4,5]. (ctsnet.org)
  • Based on the source segment, synthetic vascular graft is expected to have higher market share by 2024 in compare to biological and biosynthetic vascular grafts. (transparencymarketresearch.com)
  • Presently, synthetic vascular Grafts are most commonly used which are made of either Dacron or Teflon. (researchandmarkets.com)
  • 1,2 For example, large-diameter synthetic vascular grafts ( e.g. (rsc.org)
  • Randomized, double-blind, placebo-controlled, single-dose escalation study of PRT-201 (0.01 to 9 mg) applied to the graft-vein anastomosis and adjacent outflow vein immediately after AVG placement. (nih.gov)
  • A larger graft internal diameter minimizes stress on coronary anastomosis, and the rotatable valve allows for optimal leaflet positioning. (medtronic.com)
  • Roux-en-Y anastomosis any Y-shaped anastomosis in which the small intestine is included. (thefreedictionary.com)
  • Under fluoroscopic guidance, a 3.0 x 12 mm polytetrafluoroethylene (PTFE)-covered stent (Jostent, Abbott Vascular, Redwood City, California) was advanced into the LIMA (Figure 2) and deployed at 12 atmospheres (atm) of pressure, ensuring complete occlusion of the side branch (Figure 3A). (invasivecardiology.com)
  • of the global vascular graft market. (medindia.net)
  • This section of the report also provides market attractiveness analysis, by geography and market share analysis by key players, thus presenting a thorough analysis of the overall competitive scenario in the global vascular graft market. (medindia.net)
  • Companies Mentioned in the Report The report also profiles major players in the global vascular graft market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments. (medindia.net)
  • The global vascular graft market is forecast to reach US$3.29 bn by the end of 2024, from US$2.15 bn in 2015. (transparencymarketresearch.com)
  • The present decade will probably show the extent to which thrombolytic therapy can be applied for benefit in the management of thromboembolic occlusive vascular disease. (annals.org)