The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Cholesterol present in food, especially in animal products.
Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol.
Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol.
Fatty acid esters of cholesterol which constitute about two-thirds of the cholesterol in the plasma. The accumulation of cholesterol esters in the arterial intima is a characteristic feature of atherosclerosis.
An enzyme that catalyzes the oxidation of cholesterol in the presence of molecular oxygen to 4-cholesten-3-one and hydrogen peroxide. The enzyme is not specific for cholesterol, but will also oxidize other 3-hydroxysteroids. EC
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Cholesterol which is contained in or bound to very low density lipoproteins (VLDL). High circulating levels of VLDL cholesterol are found in HYPERLIPOPROTEINEMIA TYPE IIB. The cholesterol on the VLDL is eventually delivered by LOW-DENSITY LIPOPROTEINS to the tissues after the catabolism of VLDL to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LDL.
Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes.
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
Substances used to lower plasma CHOLESTEROL levels.
An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This enzyme has been found in the adrenal gland, gonads, liver, intestinal mucosa, and aorta of many mammalian species. EC
A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.
Steroids with a hydroxyl group at C-3 and most of the skeleton of cholestane. Additional carbon atoms may be present in the side chain. (IUPAC Steroid Nomenclature, 1987)
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.
Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.
A family of sterols commonly found in plants and plant oils. Alpha-, beta-, and gamma-isomers have been characterized.
A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.
Physiological processes in biosynthesis (anabolism) and degradation (catabolism) of LIPIDS.
Cholesterol which is substituted by a hydroxy group in any position.
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
A class of organic compounds known as STEROLS or STEROIDS derived from plants.
A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.
The process of converting an acid into an alkyl or aryl derivative. Most frequently the process consists of the reaction of an acid with an alcohol in the presence of a trace of mineral acid as catalyst or the reaction of an acyl chloride with an alcohol. Esterification can also be accomplished by enzymatic processes.
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC
Conditions with excess LIPIDS in the blood.
Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.
A family of MEMBRANE TRANSPORT PROTEINS that require ATP hydrolysis for the transport of substrates across membranes. The protein family derives its name from the ATP-binding domain found on the protein.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a choline moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and choline and 2 moles of fatty acids.
Protein components on the surface of LIPOPROTEINS. They form a layer surrounding the hydrophobic lipid core. There are several classes of apolipoproteins with each playing a different role in lipid transport and LIPID METABOLISM. These proteins are synthesized mainly in the LIVER and the INTESTINES.
A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion.
An intermediate in the synthesis of cholesterol.
A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.
A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. Filipins I, II, and IV are less important.
Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Uptake of substances through the lining of the INTESTINES.
A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.
An enzyme that catalyzes the hydrolysis of CHOLESTEROL ESTERS and some other sterol esters, to liberate cholesterol plus a fatty acid anion.
A cholesterol derivative found in human feces, gallstones, eggs, and other biological matter.
Detergent-insoluble CELL MEMBRANE components. They are enriched in SPHINGOLIPIDS and CHOLESTEROL and clustered with glycosyl-phosphatidylinositol (GPI)-anchored proteins.
Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).
A triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS.
Unsaturated derivatives of the steroid androstane containing at least one double bond at any site in any of the rings.
A class of sphingolipids found largely in the brain and other nervous tissue. They contain phosphocholine or phosphoethanolamine as their polar head group so therefore are the only sphingolipids classified as PHOSPHOLIPIDS.
A diet that contributes to the development and acceleration of ATHEROGENESIS.
A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the CELL NUCLEUS. Many of these proteins are similar in structure to known NUCLEAR RECEPTORS but appear to lack a functional ligand-binding domain, while in other cases the specific ligands have yet to be identified.
Cholesterol derivatives having an additional double bond in any position. 24-Dehydrocholesterol is DESMOSTEROL. The other most prevalent dehydrocholesterol is the 7-isomer. This compound is a precursor of cholesterol and of vitamin D3.
Blocking of a blood vessel by CHOLESTEROL-rich atheromatous deposits, generally occurring in the flow from a large artery to small arterial branches. It is also called arterial-arterial embolization or atheroembolism which may be spontaneous or iatrogenic. Patients with spontaneous atheroembolism often have painful, cyanotic digits of acute onset.
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Lipids, predominantly phospholipids, cholesterol and small amounts of glycolipids found in membranes including cellular and intracellular membranes. These lipids may be arranged in bilayers in the membranes with integral proteins between the layers and peripheral proteins attached to the outside. Membrane lipids are required for active transport, several enzymatic activities and membrane formation.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
A family of scavenger receptors that are predominately localized to CAVEOLAE of the PLASMA MEMBRANE and bind HIGH DENSITY LIPOPROTEINS.
A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.
A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
Lipid-laden macrophages originating from monocytes or from smooth muscle cells.
A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Regular course of eating and drinking adopted by a person or animal.
An NAPH-dependent cytochrome P450 enzyme that catalyzes the oxidation of the side chain of sterol intermediates such as the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol.
Elements of limited time intervals, contributing to particular results or situations.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
The rate dynamics in chemical or physical systems.
A sterol regulatory element binding protein that regulates GENES involved in CHOLESTEROL synthesis and uptake.
Layers of lipid molecules which are two molecules thick. Bilayer systems are frequently studied as models of biological membranes.
Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthesis and metabolism.
Derivatives of the saturated steroid cholestane with methyl groups at C-18 and C-19 and an iso-octyl side chain at C-17.
A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
An autosomal recessive disorder of CHOLESTEROL metabolism. It is caused by a deficiency of 7-dehydrocholesterol reductase, the enzyme that converts 7-dehydrocholesterol to cholesterol, leading to an abnormally low plasma cholesterol. This syndrome is characterized by multiple CONGENITAL ABNORMALITIES, growth deficiency, and INTELLECTUAL DISABILITY.
A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS), including APOLIPOPROTEIN A-I and APOLIPOPROTEIN A-II. They can modulate the activity of LECITHIN CHOLESTEROL ACYLTRANSFERASE. These apolipoproteins are low in atherosclerotic patients. They are either absent or present in extremely low plasma concentration in TANGIER DISEASE.
Cell surface proteins that bind lipoproteins with high affinity. Lipoprotein receptors in the liver and peripheral tissues mediate the regulation of plasma and cellular cholesterol metabolism and concentration. The receptors generally recognize the apolipoproteins of the lipoprotein complex, and binding is often a trigger for endocytosis.
A group of familial disorders characterized by elevated circulating cholesterol contained in either LOW-DENSITY LIPOPROTEINS alone or also in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins).
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES).
7-carbon saturated monocarboxylic acids.
The motion of phospholipid molecules within the lipid bilayer, dependent on the classes of phospholipids present, their fatty acid composition and degree of unsaturation of the acyl chains, the cholesterol concentration, and temperature.
Intermediate-density subclass of the high-density lipoproteins, with particle sizes between 7 to 8 nm. As the larger lighter HDL2 lipoprotein, HDL3 lipoprotein is lipid-rich.
Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits 3-hydroxy-3-methylglutaryl-CoA reductase activity and inhibits cholesterol uptake in the coronary arteries and aorta in vitro.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
An autosomal recessively inherited disorder caused by mutation of ATP-BINDING CASSETTE TRANSPORTERS involved in cellular cholesterol removal (reverse-cholesterol transport). It is characterized by near absence of ALPHA-LIPOPROTEINS (high-density lipoproteins) in blood. The massive tissue deposition of cholesterol esters results in HEPATOMEGALY; SPLENOMEGALY; RETINITIS PIGMENTOSA; large orange tonsils; and often sensory POLYNEUROPATHY. The disorder was first found among inhabitants of Tangier Island in the Chesapeake Bay, MD.
Organic compounds that contain silicon as an integral part of the molecule.
Transport proteins that carry specific substances in the blood or across cell membranes.
The processes whereby the internal environment of an organism tends to remain balanced and stable.
A condition marked by the development of widespread xanthomas, yellow tumor-like structures filled with lipid deposits. Xanthomas can be found in a variety of tissues including the SKIN; TENDONS; joints of KNEES and ELBOWS. Xanthomatosis is associated with disturbance of LIPID METABOLISM and formation of FOAM CELLS.
Fatty acids which are unsaturated in only one position.
Antilipemic agent with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.
An autosomal recessively inherited disorder caused by mutation of LECITHIN CHOLESTEROL ACYLTRANSFERASE that facilitates the esterification of lipoprotein cholesterol and subsequent removal from peripheral tissues to the liver. This defect results in low HDL-cholesterol level in blood and accumulation of free cholesterol in tissue leading to a triad of CORNEAL OPACITY, hemolytic anemia (ANEMIA, HEMOLYTIC), and PROTEINURIA.
An anticholesteremic agent that inhibits sterol biosynthesis in animals.
A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Established cell cultures that have the potential to propagate indefinitely.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Leukocyte differentiation antigens and major platelet membrane glycoproteins present on MONOCYTES; ENDOTHELIAL CELLS; PLATELETS; and mammary EPITHELIAL CELLS. They play major roles in CELL ADHESION; SIGNAL TRANSDUCTION; and regulation of angiogenesis. CD36 is a receptor for THROMBOSPONDINS and can act as a scavenger receptor that recognizes and transports oxidized LIPOPROTEINS and FATTY ACIDS.
Glucose in blood.
Fats containing one or more double bonds, as from oleic acid, an unsaturated fatty acid.
The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism.
The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.
Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.
A genus of the family Muridae having three species. The present domesticated strains were developed from individuals brought from Syria. They are widely used in biomedical research.
A large group of structurally diverse cell surface receptors that mediate endocytic uptake of modified LIPOPROTEINS. Scavenger receptors are expressed by MYELOID CELLS and some ENDOTHELIAL CELLS, and were originally characterized based on their ability to bind acetylated LOW-DENSITY LIPOPROTEINS. They can also bind a variety of other polyanionic ligand. Certain scavenger receptors can internalize micro-organisms as well as apoptotic cells.
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Animal reproductive bodies, or the contents thereof, used as food. The concept is differentiated from OVUM, the anatomic or physiologic entity.
A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.
CHOLESTENES with one or more double bonds and substituted by any number of keto groups.
Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.
The main trunk of the systemic arteries.
Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.
A class of lipoproteins that carry dietary CHOLESTEROL and TRIGLYCERIDES from the SMALL INTESTINE to the tissues. Their density (0.93-1.006 g/ml) is the same as that of VERY-LOW-DENSITY LIPOPROTEINS.
Oils derived from plants or plant products.
The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.
A group of fatty acids that contain 18 carbon atoms and a double bond at the omega 9 carbon.
Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A condition of elevated levels of TRIGLYCERIDES in the blood.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Azoles of one NITROGEN and two double bonds that have aromatic chemical properties.
A tyrosine phosphoprotein that plays an essential role in CAVEOLAE formation. It binds CHOLESTEROL and is involved in LIPIDS transport, membrane traffic, and SIGNAL TRANSDUCTION.
The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of gene (NPC1) encoding a protein that mediate intracellular cholesterol transport from lysosomes. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC
The interstitial fluid that is in the LYMPHATIC SYSTEM.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.
A spirostan found in DIOSCOREA and other plants. The 25S isomer is called yamogenin. Solasodine is a natural derivative formed by replacing the spiro-ring with a nitrogen, which can rearrange to SOLANINE.
An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes.
Cytoplasm stored in an egg that contains nutritional reserves for the developing embryo. It is rich in polysaccharides, lipids, and proteins.
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Conditions with abnormally elevated levels of LIPOPROTEINS in the blood. They may be inherited, acquired, primary, or secondary. Hyperlipoproteinemias are classified according to the pattern of lipoproteins on electrophoresis or ultracentrifugation.
Steroids with methyl groups at C-10 and C-13 and a branched 8-carbon chain at C-17. Members include compounds with any degree of unsaturation; however, CHOLESTADIENES is available for derivatives containing two double bonds.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING.
The main structural proteins of CAVEOLAE. Several distinct genes for caveolins have been identified.
Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.
CELL LINE derived from the ovary of the Chinese hamster, Cricetulus griseus (CRICETULUS). The species is a favorite for cytogenetic studies because of its small chromosome number. The cell line has provided model systems for the study of genetic alterations in cultured mammalian cells.
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
Relating to the size of solids.
A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Proteins which are present in or isolated from SOYBEANS.
A lipoprotein that resembles the LOW-DENSITY LIPOPROTEINS but with an extra protein moiety, APOPROTEIN (A) also known as APOLIPOPROTEIN (A), linked to APOLIPOPROTEIN B-100 on the LDL by one or two disulfide bonds. High plasma level of lipoprotein (a) is associated with increased risk of atherosclerotic cardiovascular disease.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
Endocytic/exocytic CELL MEMBRANE STRUCTURES rich in glycosphingolipids, cholesterol, and lipid-anchored membrane proteins that function in ENDOCYTOSIS (potocytosis), transcytosis, and SIGNAL TRANSDUCTION. Caveolae assume various shapes from open pits to closed vesicles. Caveolar coats are composed of CAVEOLINS.
Unsaturated fats or oils used in foods or as a food.
Oil from ZEA MAYS or corn plant.
(Z)-9-Octadecenoic acid 1,2,3-propanetriyl ester.
Conditions with abnormally low levels of LIPOPROTEINS in the blood. This may involve any of the lipoprotein subclasses, including ALPHA-LIPOPROTEINS (high-density lipoproteins); BETA-LIPOPROTEINS (low-density lipoproteins); and PREBETA-LIPOPROTEINS (very-low-density lipoproteins).
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Sterol regulatory element binding proteins are basic helix-loop-helix leucine zipper transcription factors that bind the sterol regulatory element TCACNCCAC. They are synthesized as precursors that are threaded into the MEMBRANES of the ENDOPLASMIC RETICULUM.
A diet that contains limited amounts of fat with less than 30% of calories from all fats and less than 10% from saturated fat. Such a diet is used in control of HYPERLIPIDEMIAS. (From Bondy et al, Metabolic Control and Disease, 8th ed, pp468-70; Dorland, 27th ed)
Highly crosslinked and insoluble basic anion exchange resin used as anticholesteremic. It may also may reduce triglyceride levels.
A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
A change of a substance from one form or state to another.
A butterlike product made of refined vegetable oils, sometimes blended with animal fats, and emulsified usually with water or milk. It is used as a butter substitute. (From Random House Unabridged Dictionary, 2d ed)
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Proteins which are present in or isolated from vegetables or vegetable products used as food. The concept is distinguished from PLANT PROTEINS which refers to non-dietary proteins from plants.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
Abstaining from all food.
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
... "good" cholesterol-containing particle) and reduces LDL levels (the "bad" cholesterol). According to Harvard Heart Letter: "HDL ... "HDL: The good, but complex, cholesterol". Buchwald, Stephen (July 23, 2004). "Research Projects". Archived from the original on ... Some types of HDL are great at plucking cholesterol from LDL and artery walls while other types are indifferent to cholesterol ... which normally transfers cholesterol from HDL cholesterol to very low density or low density lipoproteins (VLDL or LDL). ...
"Study locates cholesterol genes; finds surprises about good, bad cholesterol". 2008-01-13. Retrieved 2018-04 ... 13 January An international study of 20,000 people discovers seven genes that influence blood cholesterol levels. Following ...
A. It increases HDL ("good") cholesterol. However, the increase of HDL cholesterol is dose and disease dependent. Some ... C. It improves cholesterol (both HDL and LDL) particle size II. Alcohol decreases thrombosis (blood clotting). A. It reduces ... It is well known that alcohol consumption increases the risk of hypertension. Hence, many clinical trials examined the effect ... B. It decreases LDL ("bad") cholesterol for both healthy and patient populations though the effect is still under debate. ...
"Study locates cholesterol genes; finds surprises about good, bad cholesterol". January 10, 2008. Retrieved ... "New genes present drug targets for managing cholesterol and glucose levels". December 9, 2008. Retrieved ... Otman, Haley (December 21, 2020). "New Gene Target Could Improve Cholesterol Without Harming the Liver". ... new genes that influence blood cholesterol levels and confirmed 11 other genes previously thought to influence cholesterol. ...
"Do Cholesterol Drugs Do Any Good?". Business Week. Archived from the original on December 28, 2014. Retrieved 2008-03-31. ... There are several important problems with the NNT, involving bias and lack of reliable confidence intervals, as well as ... ASCOT-LLA manufacturer-sponsored study addressed the benefit of atorvastatin 10 mg (a cholesterol-lowering drug) in patients ... of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol ...
Low levels of good cholesterol (HDL). *Overweight or obesity. *Elevated blood pressure[11] ... Healthy meals (a diet with no saturated and trans fats, sugars, and refined carbohydrates, as well as limited the intake of ... dyslipidemia with high triglycerides and/or low HDL cholesterol, and hypertension."[2] It is thus a metabolic diathesis or ... and also have a good safety profile. Evidence also supports thiazolidinediones but there are safety concerns, and data on newer ...
Cholesterol Synthesis - has some good regulatory details. *Protein Data Base (PDB), Sterol Regulatory Element Binding 1A ... SREBP-2 regulates the genes of cholesterol metabolism.. Function[edit]. SREB proteins are indirectly required for cholesterol ... when cellular cholesterol levels fall below the level needed, the cell makes more of the enzymes necessary to make cholesterol ... where it activates the promoter of genes involved in cholesterol uptake or in cholesterol synthesis. SREBP processing can be ...
Cholesterol Synthesis - has some good regulatory details. *Protein Data Base (PDB), Sterol Regulatory Element Binding 1A ... Absence of sterols activates SREBP, thereby increasing cholesterol synthesis.[10] Insulin, cholesterol derivatives, T3 and ... when cellular cholesterol levels fall below the level needed, the cell makes more of the enzymes necessary to make cholesterol ... where it activates the promoter of genes involved in cholesterol uptake or in cholesterol synthesis. SREBP processing can be ...
Mitchell-Whittington, Amy (15 January 2018). "Scientists find 'good' cholesterol could increase risk of eye disease". Brisbane ... as well as the role of natural selection in driving genetic variation in such traits. He and his colleagues have also used ... as well as an affiliated professor at the Queensland Brain Institute. He received the 2015 Ruth Stephens Gani Medal for his ...
... "bad cholesterol") and triglyceride concentrations. However, high-density lipoprotein (HDL, "good cholesterol") did not increase ... It is often seasoned or marinated to suit the dish and its flavors, and due to its spongy texture it absorbs flavors well. ... It spread to other parts of Southeast Asia as well. This probably coincided with the spread of Buddhism as it is an important ... As such, many tofu manufacturers choose to use this coagulant to be able to market their tofu as a good source of dietary ...
Cheraskin, E. "If High Blood Cholesterol Is Bad-Is Low Good?." Journal of orthomolecular medicine 1.3 (1986): 176-183. Bock, U ... Taylor, G. Oladunni; Agbedana, E. O.; Johnson, A. O. K. (May 1982). "High-density-lipoprotein-cholesterol in protein-energy ... Taylor, Grace Oladunni; Bamgboye, Afolabi E. (December 1979). "Serum cholesterol and diseases in Nigerians" (PDF). The American ... and changes in plasma total and HDL-cholesterol levels during treatment of hypertension in African patients" (PDF). Acta Medica ...
... is also affected by cholesterol. Cholesterol can make the cell membrane fluid as well as rigid. Membrane ... At 37°C, this is the state of the membrane: the presence of cholesterol, though, allows for the membrane stabilization and a ... Such membranes can be described as "a glass state, i.e., rigid but without crystalline order". Cholesterol acts as a ... and the lipid chains are mostly in the all-trans configuration and pack well together. The melting temperature T m {\ ...
He suffered from high cholesterol and high blood pressure as well. In 2012, Stump was elected a member of the National Academy ... There was a rumor that he was not paid for this episode, but he has debunked that and said that he was paid well for his ... His TV guest appearances include Good Morning New Orleans, The Tonight Show with Jay Leno, and Hoppus on Music. In a blog post ... In 2008, he executive- and co-produced The Cab's Whisper War and Gym Class Heroes' The Quilt, as well as several tracks on ...
"Fats and Cholesterol: Out with the Bad, In with the Good". The Nutrition Source. Harvard School of Public Health. Retrieved ... A good potential source of special fatty acids, carotenoids, tocopherols, phenol compounds and natural anti-oxidants, as well ... A good dietary equivalent to fish oil. Easily turns rancid. Amaranth oil, from the seeds of grain amaranth species, including ... Pecan oil, valued as a food oil, but requiring fresh pecans for good quality oil. Pine nut oil, sold as a gourmet cooking oil, ...
... cholesterol) or low levels of high-density lipoprotein (HDL, "good" cholesterol). These parameters in turn are believed to be ... "bad cholesterol"), lowering levels of high-density lipoprotein (HDL, often termed "good cholesterol"), increasing triglycerides ... "good cholesterol"). The net increase in LDL/HDL ratio with trans fat, a widely accepted indicator of risk for coronary artery, ... The shape of fat and fatty acid molecules is usually not well-defined. Any two parts of a molecule that are connected by just ...
Jícama is very low in saturated fat, cholesterol, and sodium. It is also a good source of vitamin C.[14] ... Jicama is frost-tender and requires 9 months without frost for a good harvest of large tubers or to grow it commercially. It is ...
Insulin resistance contributes to the changes of cholesterol synthesis and absorption as well. However, nothing is known about ... or OXT agonists may represent a promising approach for the management of obesity and related metabolic diseases as well as ...
Rearrangements of glycosphingolipids, phospholipids, as well as cholesterol explains changes in membrane fluidity. Some studies ... Dietary sources involved in the construction of lipid raft, n-3 PUFA from oil fish as well as polyphenols, affect the molecular ... One of its most important characteristics is its sensitivity to membrane phase transitions as well as other alterations to ... "Triton X-100 promotes cholesterol-dependent condensation of the plasma membrane" (PDF). Biochem. J. 420 (3): 373-381. doi: ...
"Cholesterol: The good, the bad, and the truth" [1] (retrieved 3 June 2011) Dons, E (2018). "Transport mode choice and body mass ... Example 6 HDL ("good") cholesterol is negatively correlated with incidence of heart attack. Therefore, taking medication to ... Another well-known example is that cyclists have a lower Body Mass Index than people who do not cycle. This is often explained ... Well-designed experimental studies replace equality of individuals as in the previous example by equality of groups. The ...
This is because it boosted levels of 'good' HDL cholesterol in the bloodstream. Today, most skim milk is created by spinning ...
Daily consumption of fresh vegetables is good for reducing cholesterol levels and improving digestive health. Vegetables are ...
... as well as naturally low in cholesterol. Flavor and aroma is described as mild. Meat is judged as having good flavor, juiciness ... They are well adapted to the hot humid climate of the tropics and can survive in cold temperatures. Their hair coat lets them ... Croix have a good herding instinct and are often used to train herding dogs. St. Croix sheep are both grazers and browsers. ...
"Fats and Cholesterol: Out with the Bad, In with the Good - What Should You Eat? - The Nutrition Source". Harvard School of ... Bach D, Wachtel E (March 2003). "Phospholipid/cholesterol model membranes: formation of cholesterol crystallites". Biochimica ... as well as other sterol-containing metabolites such as cholesterol. Although humans and other mammals use various biosynthetic ... Fats that are good for you can be turned into trans fats by overcooking. A few studies have suggested that total dietary fat ...
Obesity is associated with increased LDL cholesterol (bad cholesterol) and lowered HDL cholesterol (good cholesterol). Obesity ... According to NIH, obesity causes the amount of cholesterol in bile to rise, in turn the formation of stone can occur Due to its ... In women, class II obesity (i.e. BMI = 35) is a risk factor for osteoporotic fractures in general, as well as for upper arm ... These mechanisms include the activation of the sympathetic nervous system as well as the activation of the renin-angiotensin- ...
A defect in the body's production of cholesterol can lead to adverse consequences as well. Cholesterol is an essential ... It is possible that whatever causes the low cholesterol level also causes mortality, and that the low cholesterol is simply a ... In the elderly, low cholesterol may confer a health risk that may not be offset by the beneficial effects of cholesterol ... 1994). Very Low Cholesterol and Cholesterol Lowering. Leaflet 71-0059. American Heart Association. Suarez EC (1 May 1999). " ...
He studied histamine release, as well as groundbreaking work in lipids and the absorption of cholesterol. In 1973, The National ... He is the co-editor, with Walford Gillison, of Pioneers in Surgical Gastroenterology (2007), as well as the co-author, with ... The results from all phases of the POSCH study have contributed significant insights and long-term data related to cholesterol ... The POSCH study definitely proved the link between cholesterol and heart disease. The POSCH trials demonstrated conclusively ...
... it is good for the skin and it is effective for declining cholesterol and preventing hypertension. Additionally, it is rich in ...
It is well known that high blood pressure or high cholesterol levels increase a patient's risk. What is less well known is that ... The implications for private equity could well be severe. Being unable to sell businesses to generate proceeds and fees means ... blood pressure or blood cholesterol level) while the y-axis measures the chance that a patient will develop cardiovascular ... mortality often take the shape of a J curve which indicates that patients with very low blood pressure and/or low cholesterol ...
Of those, 40 (20%) turn out to be on a list of cholesterol genes as well. Based on the overall prevalence of the cholesterol ... Second, even if protein levels do change, perhaps there is always enough of them around to make cholesterol as fast as it can ... Good experimental design, adequate biological replication and follow up experiments play key roles in successful expression ... Suppose there are 10,000 genes in an experiment, only 50 (0.5%) of which play a known role in making cholesterol. The ...
"LDL and HDL Cholesterol: What's Bad and What's Good?". American Heart Association. 2 July 2009. Consultado o 8 October 2009.. ... "National Reference System for Cholesterol - Cholesterol Reference Method Laboratory Network - HDL Cholesterol Certification ... "Cholesterol Levels". American Heart Association. Consultado o 14 November 2009.. *↑ "What Do My Cholesterol Levels Mean?" (PDF) ... "Good Cholesterol" High-Density Lipoprotein". Circulation 111 (5): e89-e91. PMID 15699268. doi:10.1161/01.CIR.0000154555.07002. ...
... "the good cholesterol". Clinically, the choice of an agent depends on the patient's cholesterol profile, cardiovascular risk, ... Statins (HMG-CoA reductase inhibitors) are particularly well suited for lowering LDL, the cholesterol with the strongest links ... Fibrates typically lower triglycerides by 20% to 50%. Level of the good cholesterol HDL is also increased. Fibrates may ... Hypolipidemic agents, cholesterol-lowering drugs or antihyperlipidemic agents, are a diverse group of pharmaceuticals that are ...
... high cholesterol, and microalbuminuria, improves a person's life expectancy.[25] Decreasing the systolic blood pressure to less ... blood sugar levels being well controlled).[25] When nightly insulin is insufficient, twice daily insulin may achieve better ...
... "good," "very good," or "excellent"-overall, about 25% higher than the average; ... Women were 60% more likely to have mammograms, and recipients overall were 20% more likely to have their cholesterol checked; ... The annual cost of care will vary state to state depending on state approved Medicaid benefits, as well as the state specific ... "Medicaid Reimbursement and Training Enable Primary Care Providers to Deliver Preventive Dental Care at Well-Child Visits, ...
... bedtime dosing is effective as well.[11] A recent study published in JAMA showed greater efficacy of levothyroxine when taken ... elevated cholesterol levels) but was withdrawn due to cardiac side effects. ... by affecting iodine metabolism of the thyroid itself and thus inhibits synthetic levothyroxine as well.[26] ... low TSH levels are also well known to contribute to osteoporosis).[21] ...
Russert died on June 13, 2008, of a sudden coronary thrombosis (caused by a cholesterol plaque rupture).[17] Former NBC Nightly ... The program is also syndicated by Westwood One to various radio stations around the United States, as well as on C-SPAN Radio ... if Buffalo's NHL hockey team was doing well. Spoofs of the show featured in a recurring sketch on Saturday Night Live often ...
... s are synthesized from cholesterol and are produced primarily in the gonads (testicles and ovaries) and also in the ... and androgens mediate the development of masculine secondary sexual characteristics as well as the activation of ... Dehydroepiandrosterone (DHEA) is a steroid hormone produced in the adrenal cortex from cholesterol.[4] It is the primary ...
... as well as boys with precocious puberty.[6] They have also been used to treat men with priapism.[7][8] In women, antiandrogens ... Aminoglutethimide inhibits cholesterol side-chain cleavage enzyme, also known as P450scc or CYP11A1, which is responsible for ... as well as the presence of off-target activity in the antiandrogen in question.[18][71] For instance, whereas antigonadotropic ... as well as the conversion of mineralocorticoids into glucocorticoids.[61][62] Because these drugs all prevent the formation of ...
Research has suggested that job loss adversely affects cardiovascular health[20][82] as well as health in general.[83][84] ... These risk factors include smoking, obesity, low density lipoprotein (the "bad" cholesterol), lack of exercise, and blood ... Eds.), Work and well-being: Assessments and instruments for occupational mental health (pp. 19-32). Washington, DC: American ... Eds.) (1992). Work and well-being: Assessments and instruments for occupational mental health. Washington, DC: American ...
Neurosteroids are synthesized in the central nervous system (CNS) and the peripheral nervous system (PNS) from cholesterol and ... binding may involve a pocket formed by β-subunit methionine 286 as well as α-subunit methionine 236.[9] ... In 2013 the barbiturates phenobarbital and butabarbital are still used as sedatives in certain cases as well as to antagonize ...
"Excerpt from Good Calories, Bad Calories and NPR interview with Gary Taubes and Dr. Ronald Krauss (2 November 2007). ... lipoprotein cholesterol values should be weighed against potential unfavorable changes in low-density lipoprotein cholesterol ... The passages strongly suggest that the Daniel Fast will promote good health and mental performance.[18] ...
However, statins are not as good at increasing the HDL (good) cholesterol. Low HDL is hard to treat with medicines, but goes up ... Types of cholesterol[change , change source]. Not all cholesterol is bad. There are different kinds of cholesterol in the blood ... Cholesterol is usually in the walls of cells. It is only in animals. Plants do not synthesize cholesterol. So the cholesterol ... good cholesterol' because people with high levels of HDL cholesterol have less atherosclerosis. ...
September 2002). "Well-done red meat, metabolic phenotypes and colorectal cancer in Hawaii". Mutat. Res. 506-507: 205-14. doi: ... mechanism was uncovered as damage to the macrophage membrane's lipid raft integrity by decreasing membrane cholesterol at 25%. ... A 2001 National Cancer Institute study found levels of BaP to be significantly higher in foods that were cooked well-done on ...
The role of early life stress in programming the HPA Axis has been well-studied in animal models. Exposure to mild or moderate ... where it rapidly stimulates biosynthesis of corticosteroids such as cortisol from cholesterol. Cortisol is a major stress ... As well as directly increasing glucose availability, cortisol also suppresses the highly demanding metabolic processes of the ... Specifically, by instating specific patterns of HPA axis activation, the individual may be more well equipped to cope with ...
... which further affects digestive function and cholesterol and glucose metabolism, as well as the immune system and other ... and rye have been studied for their effects on cholesterol levels in people with normal cholesterol levels and in those with ... At dietary intake levels of at least 3 g per day, oat fiber β-glucan decreases blood levels of LDL cholesterol and so may ... A particular interest in oat β-glucan arose after a cholesterol lowering effect from oat bran reported in 1981.[2] ...
Pharmacological options exist, as well. Medicines that control lipid profile, diabetes, and hypertension may increase blood ...
Even when it becomes just cool enough to be sipped gingerly, it is still a good-tasting cup of tea, if you like your tea strong ... study demonstrated that regular consumption of black tea over four weeks had no beneficial effect in lowering blood cholesterol ... as well as tea.[14] In the Chronicles of Huayang, it was recorded that the Ba people in Sichuan presented tu to the Zhou king. ... These blocks of instant tea, powdered milk, and sugar were not always well received. As Royal Canadian Artillery Gunner, George ...
It contains no cholesterol and the energy content is about 17 Calories.[3] Egg white is an alkaline solution and contains ... Good Eats, Let Them Eat Foam. DVD. Television Food Network, June 13, 2001. ...
Gohyah Tea is good for bile, liver, dieuretic. Helpful to digestion; prevent from influenza, throat inflammation. Reduce ... cholesterol in the blood.. Gohyah is not listed in the Grieve's herbal database, the MPNA database at University of Michigan ( ...
This measures total cholesterol, LDL (bad) cholesterol, HDL (good) cholesterol and triglycerides. It is recommended to have ... has total cholesterol of 200 mg/dL or more, if a man over age 45 or a woman over age 50, has HDL (good) cholesterol less than ... that are water-dispersible and carry cholesterol and triglycerides as well as phospholipids and cholesterol esters. ... Given the well-recognized role of cholesterol in cardiovascular disease, it is surprising that some studies have shown an ...
If you keep fast, then do it a way so that you adopt the compassion, well being and ask for good will of everyone. "Let your ... such as cholesterol testing (lipid panel) or certain blood glucose measurements require fasting for several hours so that a ... Not eating a meal in the evening I, monks, am aware of good health and of being without illness and of buoyancy and strength ... Without the Guru's word in the company of Saints one does not get refuge no matter how good one looks." (Bhai Gurdas Ji, Vaar 7 ...
Peroxisomal disorders are a class of medical conditions that typically affect the human nervous system as well as many other ... It is vigorously debated whether peroxisomes are involved in isoprenoid and cholesterol synthesis in animals.[4] Other known ...
It was patented in 1969 and approved for medical use in 1982.[2] It sold well, but in 2009, Roche decided to discontinue ... Isotretinoin and other retinoids are well known to affect the eyes. Dry eyes are very common during treatment and is caused by ... In 2012, a systematic review covering all articles in the literature related to isotretinoin, depression and suicide, as well ... are well known to cause bone changes, the most common type of which is hyperostotic changes (excessive bone growth), especially ...
"LDL Cholesterol and Oatmeal". WebMD. 2 February 2009.. *^ a b c "Title 21--Chapter 1, Subchapter B, Part 101 - Food labeling - ... Usage and Abusage: A Guide to Good English (1st American ed.). New York: W.W. Norton, 1995. p. 82. ISBN 978-0-393-03761-6.. ... The established property of their cholesterol-lowering effects[1] has led to acceptance of oats as a health food.[15] ... Its daily consumption over weeks lowers LDL and total cholesterol, possibly reducing the risk of heart disease.[1][16] ...
In the case of glomerular damage occurring in HN, hematuria can occur as well.[citation needed] ... despite the well-known association between hypertension and chronic kidney disease, the underlying mechanism remains unclear. ...
However, these strains do not overwinter well, so are not often found in the colder, more northern parts of North America. The ... foods low in cholesterol (ID 624); and foods low in trans-fatty acids (ID 672, 4333) pursuant to Article 13(1) of Regulation ( ... including the Western honey bee as well as Apis cerana, are known to engage in effective methods of nest thermoregulation ... Novel hybrid strains of domestic and redomesticated Africanized bees combine high resilience to tropical conditions and good ...
Fatty Acids and Cholesterol Contents and Nutritional Value of Protein". College of Foods and Agricultural Science. King Saud ... Good articles. *Articles containing Greek-language text. *Instances of Lang-el using second unnamed parameter ... and 286 mg of cholesterol.[81] Among the fatty acids, palmitoleic, oleic and linolenic acids were found to be the most abundant ...
Generally, the bulk of their structure is nonpolar or hydrophobic ("water-fearing"), meaning that it does not interact well ... This makes them amphiphilic molecules (having both hydrophobic and hydrophilic portions). In the case of cholesterol, the polar ... would expand food chemistry as well with research of the dietary substances, most notably the Single-grain experiment during ...
A corneal dystrophy can be caused by an accumulation of extraneous material in the cornea, including lipids and cholesterol ... With penetrating keratoplasty (corneal transplant), the long-term results are good to excellent. Recent surgical improvements ... Main differential diagnosis include various causes of monoclonal gammopathy, lecithin-cholesterol-acyltransferase deficiency, ...
Phaseolus vulgaris (common bean; includes the pinto bean, kidney bean, black bean, Appaloosa bean as well as green beans, and ... Soluble fiber can help lower blood cholesterol.[23] Adults are recommended to have up to two (female), and three (male) ... Cooking beans, without bringing them to the boil, in a slow cooker at a temperature well below boiling may not destroy toxins.[ ... Bean poisoning is not well known in the medical community, and many cases may be misdiagnosed or never reported; figures appear ...
Cholesterol stonesEdit. Cholesterol stones vary from light yellow to dark green or brown or chalk white and are oval, usually ... "Should you lose weight fast? - Live Well-NHS Choices". Archived from the original on 2016-02-16. Retrieved 2016-02- ... Cholesterol gallstones develop when bile contains too much cholesterol and not enough bile salts. Besides a high concentration ... Numerous small gallstones made up largely of cholesterol. Pronunciation. *Cholelith /ˈkoʊləlɪθ/, cholelithiasis /ˌkoʊləlɪˈθaɪəs ...
So cholesterol can be good and bad. There are also different types of cholesterol sometimes called "good cholesterol" and "bad ... Cholesterol Good and Bad. ... Heres how cholesterol can be good.. Cholesterol is found in all of our cells. Cells need it to keep their membranes just the ... HDL, or high-density lipoprotein, is sometimes called "good cholesterol". It takes cholesterol away from the blood and returns ...
... good cholesterol. It helps to remove bad cholesterol from your arteries, so a higher HDL level is better. ... Cholesterol Good and Bad (National Library of Medicine) Also in Spanish * Cholesterol Levels (National Library of Medicine) ... It is sometimes called the "good" cholesterol because it carries cholesterol from other parts of your body back to your liver. ... Cholesterol testing and results (Medical Encyclopedia) Also in Spanish * Niacin for cholesterol (Medical Encyclopedia) Also in ...
About Cholesterolplus icon *LDL and HDL Cholesterol: "Bad" and "Good" Cholesterol ... HDL (high-density lipoprotein), or "good" cholesterol, absorbs cholesterol and carries it back to the liver. The liver then ... LDL and HDL Cholesterol: "Bad" and "Good" Cholesterol. ... High Cholesterol Statistics and Mapsplus icon *High Cholesterol ... Cholesterolexternal icon-American Heart Association. *High Blood Cholesterol: What You Need to Knowexternal icon-National Heart ...
Researchers find that just short-term lack of sleep may have a big influence on cholesterol, shedding light on why sleep ... Good cholesterol might actually be bad A large new study in the general population has found a link between excessive ... Good cholesterol levels reduced with high air pollution exposure Researchers have found that higher exposure to traffic- ... "Sleep deprivation may lower good cholesterol." Medical News Today. MediLexicon, Intl., 24 Apr. 2016. Web.. 25 May. 2019. , ...
... good, cholesterol may help protect against the effects of multiple sclerosis, according to new research. ... Other research has looked at prescribing cholesterol-lowering drugs, known as statins, to increase good cholesterol in MS ... 12, 2013 -- A protein found in HDL, or good, cholesterol may help protect against the effects of multiple sclerosis, ... Compared to those without MS, all the MS patients had lower levels of the cholesterol protein. This was true no matter what ...
While there are dozens of books on cholesterol out there, Cholesterol Is Not the Culprit was written by the person who first ... Oxidized cholesterol (again, not dietary cholesterol in and of itself) causes increased thromboxane formation-a factor that ... The other one is oxidized cholesterol, formed when cholesterol is heated. The primary source of the latter is fried foods. ... Despite that, the saturated fat/cholesterol myth has persisted.. After researching the science of lipids, cholesterol, heart ...
... but questions still linger about the role of good cholesterol. Dr. Mallika Marshall explains. ... Getting bad cholesterol under control is important in battling heart disease, ...
... overeating omega-6 Omega-3 oleic acid Nutrition linoleic acids LDL Jenna Channell hydrogenation HDL good fats good cholesterol ...
... cholesterol can reduce the risk of heart disease. But after a string of surprising clinical trials, theyre not sure whether ... New Rules for Giving Good Cholesterol a Boost. In the war against heart-damaging high cholesterol, a promising weapon has been ... good cholesterol to be no more effective at warding off heart disease than widely used bad-cholesterol-cutting drugs alone. ... or so-called good cholesterol, have long been shown as a predictor of heart disease, since HDLs help ferry bad cholesterol away ...
Its not enough to measure total cholesterol levels anymore. What you need to know is the status of your ... Just when you thought you knew everything about cholesterol testing, along comes more advice: ... If your total cholesterol still isnt lowered, medication might be prescribed. Raising the levels of good cholesterol helps ... The National Cholesterol Education Program publishes a brochure on cholesterol and another on low-cholesterol eating. ...
Good news for good cholesterol. Positive results inject life into strategy to treat heart disease. ... good cholesterol--might have a stronger protective effect against heart disease than statins, drugs that lower levels of low- ... This week, the first study since to focus on the class of drugs that boosts HDL levels may offer good news for the approach. ... density lipoprotein (bad cholesterol or LDL). But in 2006, a $1-billion trial of torcetrapib, an HDL-raising drug, found it ...
Spotlight on: Cholesterol. * What Is Cholesterol?. Taking a close look at cholesterol, a fat (lipid) produced by the liver. ... "The cholesterol mechanism is crucial to heart disease," Gupta said. "Very few agents increase good cholesterol, but we found ... "good cholesterol," which work in part by carrying cholesterol out of the arterial wall. Results of her study, titled " ... "Good Cholesterol Levels Increased By Algae Extract." Medical News Today. MediLexicon, Intl., 9 Jul. 2012. Web.. 23 Nov. 2017. , ...
Hence, interpreting the rising share of FDI as a sign of good health is unwarranted. This is even more so, given that FDI`s ... the share of FDI in total flows is not an indication of good health. On the contrary, countries that are riskier, less ... "Foreign Direct Investment: Good Cholesterol?," IDB Publications (Working Papers) 1319, Inter-American Development Bank. ... Hence, interpreting the rising share of FDI as a sign of good health is unwarranted. This is even more so, given that FDI`s ...
... bad cholesterol is lowered, researchers said on Wednesday. ... good cholesterol in the blood remains an important marker for ... Among patients taking cholesterol-lowering drugs called statins, the higher the HDL or good cholesterol, the less likely they ... "good cholesterol" in the blood remains an important marker for heart disease regardless of how much "bad cholesterol" is ... good cholesterol in the blood remains an important marker for heart disease regardless of how much bad cholesterol is ...
Suffice to say that the 71-year-old presumptive Republican presidential nominee had high cholesterol and was taking Vytorin ... They report that his cholesterol level subsequently went up slightly, but that its still "acceptable." ... If he got himself a good agent, maybe thered even be a bidding war. ... maybe McCain will go the route of Bob Dole with Viagra and become a pitchman for one of the cholesterol drugs. Dont think it ...
Theres a reason HDL cholesterol is called "good" cholesterol: Raising the bodys levels of HDL could lower your risk of heart ... Why High Levels of Good Cholesterol Might Not Be As Great As You Think ... So whats going on? The LDL-lowering medication may have worked so well that it masked any benefits of increasing "good" HDL ... Heres one approach to lowering cholesterol-and improving heart health-thats been proven over and over again: Diet and ...
... eating eggs doesnt negatively impact your cholesterol at all, but they do offer crucial nutrients, including choline, and can ... eating eggs doesnt negatively impact your cholesterol at all, but they do offer crucial nutrients, including choline, and can ... The belief that eggs are bad for your cholesterol is a myth; in fact, ... The belief that eggs are bad for your cholesterol is a myth; in fact, ...
It is harder to raise HDL cholesterol levels than it is to lower LDL levels, but aerobic exercise and niacin can help, says Dr ... Your LDL cholesterol level should be below 70 mg/dL.. However, it is still important to keep your HDL cholesterol at an ... There are two types of cholesterol that play a role in heart disease. Low-density (LDL) cholesterol leads to streaks of fatty ... There are two types of cholesterol that play a role in heart disease. Low-density (LDL) cholesterol leads to streaks of fatty ...
... is well known as THE most effective way to improve cholesterol levels by INCREASING cholesterol levels- in a good way.. High ... good cholesterol that is an overall contributor to good health. Whats talked about even LESS is the fact that niacin, one of ... is that humans actually NEED cholesterol for good health. Interestingly, there are different types of cholesterol: bad ... Niacin Increases Good Cholesterol. by Kerri Knox, RN (NaturalNews) In the past decade doctors have declared an all out war on ...
Reddys Laboratories said it is developing a drug that boosts good cholesterol, as the Indian company joins global majors ... said Friday it is developing a drug that boosts good cholesterol, as the Indian company joins global majors working on a new ...
home / cholesterol health center / cholesterol a-z list / diet, exercise may boost good cholesterol, study article ... And this so-called "good" cholesterol, or HDL cholesterol, has been linked to positive effects for cardiovascular health. ... Lower Your Cholesterol, Save Your Heart. Need to lower your cholesterol levels? Use these smart diet tips to quickly and easily ... In addition, while levels of "bad" LDL cholesterol did not change, levels of the fat hormone adiponectin and HDL cholesterol ...
... good, cholesterol, according to a meta-analysis study in the May 28 issue of Archives of Internal Medicine, one of the JAMA/ ... Newswise - Regular exercise appears to modestly increase levels of high-density lipoprotein, or "good," cholesterol, according ... The effect of exercise was greater in those who had a higher total cholesterol level (220 milligrams per deciliter or greater) ... A low level of high-density lipoprotein cholesterol (HDL-C) is an independent risk factor for cardiovascular disease, the ...
... good cholesterol in middle age may have a higher risk of memory loss and dementia in later life. ... People with low levels of a form of good cholesterol in middle age may have a higher risk of memory loss and dementia in ... HDL cholesterol serves several vital biological functions.. It helps clear excess cholesterol from the blood; assists nerve- ... The researchers say the mechanism linking HDL cholesterol to dementia is unclear but suggest that HDL cholesterol prevents ...
Additionally, apoA1 was shown to enhance arterial relaxation responses, as well as decrease airway hyper-responsiveness and the ... findings that may clarify observations linking abnormal cholesterol and/or apolipoprotein levels with pulmonary irregularities. ...
To increase your good cholesterol and keep your bad cholesterol as low as possible, the AHA advises healthy adults to consume a ... "good" cholesterol. A high concentration of HDL is linked to a lower overall blood cholesterol total and a decreased risk of ... Effect on Cholesterol. A diet rich in EPA and DHA from seafood such as sardines increases your bloods level of high-density ... This is because HDL is responsible for transporting low-density lipoproteins -- LDL, or "bad" cholesterol -- to your liver ...
Researchers are now questioning how good, so-called "good" cholesterol really is. ... therefore bringing up HDL levels is good for your health. ... How good is "good" cholesterol?. by News Staff. Posted May 17, ...
We all know that cholesterol is the main cause of heart attacks. Making simple lifestyle and dietary changes can greatly ... There are two types of cholesterol - good and bad. LDL is bad cholesterol, while HDL is considered to be good cholesterol. ... How to increase good cholesterol We all know that cholesterol is the main cause of heart attacks. Making simple lifestyle and ... Reducing bad cholesterol and increasing the good cholesterol significantly lowers the risk of heart attack. High levels of HDL ...
When Good Cholesterol Is Bad for Older Women By Amy Norton. HealthDay Reporter FRIDAY, July 20, 2018 (HealthDay News) -- HDL ... cholesterol may be known as the "good" kind, but a new study suggests high levels of it are not always a good thing for women ... HDL is known as the "good" cholesterol because it does positive things, including clearing fat from the arteries and ushering ... But experts said the findings add to evidence that when it comes to HDL, there can be too much of a good thing. ...
Foods that boost good cholesterol levels in the body are those rich in monounsaturated, polyunsaturated and omega-3 fatty acids ... Good cholesterol or high-density lipoprotein functions to sequester excess cholesterol from the blood and transport them to the ... What types of foods raise HDL cholesterol levels?. A: Foods that contain polyunsaturated fats and monounsaturated fats, as well ... Foods that boost good cholesterol levels in the body are those rich in monounsaturated, polyunsaturated and omega-3 fatty acids ...
  • It carries cholesterol that can stick to arteries, collect in the vessel lining forming plaque, and sometimes block blood flow. (
  • It is sometimes called the "bad" cholesterol because a high LDL level leads to a buildup of cholesterol in your arteries. (
  • HDL cholesterol is responsible for removing low-density lipoproteins (LDL) - the "bad" cholesterol - from the arteries. (
  • LDL cholesterol contributes to atherosclerosis - a build-up of plaque in the arteries that can increase the risk for heart attack and stroke - so a robust HDL cholesterol level is important for protecting heart health. (
  • These findings cast dark clouds over what many scientists have long seen as the next-most promising avenue of cholesterol treatment after statin drugs, which slash the 'bad' cholesterol that accumulates in the arteries. (
  • Eggs became a target based on the faulty premise of the medical establishment that eating too many yolks would drive up cholesterol and pack your carotid arteries with plaque. (
  • Low-density (LDL) cholesterol leads to streaks of fatty deposits that narrow the heart's coronary arteries, and can lead to heart disease. (
  • High-density (HDL) cholesterol is thought to help scour the arteries for these deposits and help remove them. (
  • Commenting on the study, Dr Susanne Sorensen, head of research at the Alzheimer's Society, said: 'One of the functions of HDL is to transport cholesterol from the arteries back to the liver to be degraded, so it is clearly important to have enough of this transporter available. (
  • High cholesterol in the blood initiates the process of plaque formation, which narrow the arteries and leads to heart diseases. (
  • HDL is known as the "good" cholesterol because it does positive things, including clearing fat from the arteries and ushering it to the liver to be removed. (
  • High blood cholesterol can lead to cholesterol buildup and blockage in your arteries, which can cause complications such as stroke and heart disease. (
  • Saturated fats increase low-density lipoprotein (LDL), or "bad," cholesterol that clogs the arteries. (
  • They raise high-density lipoprotein (HDL), or "good," cholesterol, which helps prevent cholesterol buildup in the arteries. (
  • Researchers from the Walter Reed Army Medical Center in Washington, D.C., found patients who were given a higher dose of a synthetic cholesterol-lowering drug not only had significantly lower levels of "bad" cholesterol after treatment than those given a regular dose of a similar medication, but they also showed a decrease in thickness in the main neck arteries supplying blood to the brain. (
  • In addition to testing for cholesterol levels, all patients underwent ultrasound to gauge the thickness of their carotid arteries at six months and one year following the initiation of treatment. (
  • He said that "research from UCLA established more than two decades ago that HDL cholesterol could -- in certain individuals (including those with very high levels of HDL) and in certain circumstances -- be dysfunctional and pro-inflammatory," and contribute to narrowing of the arteries. (
  • Angioplasty may be used to treat blocked coronary arteries caused by high levels of cholesterol in the blood. (
  • High low-density lipoprotein ( LDL ) cholesterol levels are linked to clogged arteries and ultimately the increased risk of having a heart attack . (
  • On the other hand, high-density lipoprotein ( HDL ) is often referred to as the good type of cholesterol, as it plays a role in keeping the arteries from getting clogged. (
  • People who regularly consume fatty and fried foods are at increased risk for bad cholesterol levels and clogged arteries. (
  • LDL cholesterol should be 3mmol/L or less for healthy adults as per the official NHS advice, but the ratio of LDL to high-density lipoprotein (HDL) cholesterol - the good stuff that helps keep the arteries clear - is just as important. (
  • Almonds work by gathering cholesterol from tissues, like the arteries, and helping transport it out of the body. (
  • It helps to carry away low density lipoproteins (LDL), the bad type of cholesterol, before it has a chance to adhere to the inside of your arteries - particularly the coronary arteries that supply blood to your heart. (
  • LDL is almost always referred to as the "bad" cholesterol because it is often found as a buildup in the walls of arteries. (
  • HDL, usually called the "good cholesterol," often helps remove cholesterol from the arteries. (
  • Good cholesterol' usually protects the arteries by helping to transport 'bad cholesterol' to the liver to be processed. (
  • Excessive LDL cholesterol is the main cause of atherosclerosis, a stiffening of the arteries that can lead to cardiovascular diseases. (
  • But it has also been proved that HDL cholesterol protects the arteries against this phenomenon, and helps keep the cardiovascular system healthy. (
  • It is this type of cholesterol that ends up in the walls of our arteries that is responsible for the beginnings of atherosclerosis, which is coronary disease, which is what the process of narrowing an artery that leads to chest pain and heart attacks. (
  • LDL cholesterol is considered the "bad" cholesterol, because it contributes to fatty buildups in arteries ( atherosclerosis ). (
  • Experts believe that HDL acts as a scavenger, carrying LDL (bad) cholesterol away from the arteries and back to the liver, where the LDL is broken down and passed from the body. (
  • Dr. Dippel says the drug will be tested on patients who are undergoing treatment to lower their cholesterol, adding, "The exciting part is that the drug…may not only slow down the disease process, but actually reduce hardening of the arteries. (
  • A bloodstream tussle takes place between "bad" cholesterol dumping fatty material in the arteries and good cholesterol taking it away. (
  • Atherosclerosis, better known as hardening of the arteries, typically occurs as the result of high blood pressure, smoking and/or cholesterol. (
  • NEW ORLEANS, March 26 /CNW/ -- CSL Limited today announced results from a study published in the Journal of the American Medical Association that suggest infusions of a novel new drug, CSL-111, to acutely raise HDL ("good" cholesterol) levels, may reduce the amount of plaque in the coronary arteries of patients with a recent episode of acute coronary syndrome (ACS). (
  • The reason that so many doctors care about it is because cholesterol is involved in plaques in arteries and the disease process that causes strokes and heart attacks. (
  • HDL works in a number of ways, but importantly it helps transport other cholesterol particles from tissues and blood back to the liver, including helping to remove "bad" or low-density liopoprotein (LDL) cholesterol from plaques in arteries. (
  • High concentrations of LDL cholesterol are associated with plaque formation in the arteries, and it is these plaques that can narrow arteries or rupture and cause heart attacks and strokes. (
  • Because these molecules transport cholesterol away from the arteries to the liver, HDL-C is commonly viewed as 'good' cholesterol and has been associated with reduced risk of coronary heart disease. (
  • While HDL cholesterol circulates in the blood, it attracts the fat particles that are deposited in the arteries preventing arteriosclerosis. (
  • This prevents atheroma, that is the accumulation of cholesterol in the arteries and can cause many cardiovascular diseases. (
  • Yes, high LDL levels are bad news as a build up in LDL cholesterol can cause atherosclerosis (narrowing of the arteries) and other health complaints, but does a high level of HDL or good cholesterol always mean a healthy heart? (
  • Cholesterol plays an important role in the formation of some hormones, bile and Vitamin D. However, LDL cholesterol is atherogenic, which means that high LDL levels can cause plaques (or fatty deposits) to build up in your arteries, when the arteries narrow in this way it is difficult for the blood to get through to your organs. (
  • As HDL collects up LDL cholesterol, it stops it from building up in the arteries and causing potential problems. (
  • While elevated LDL-C, known as "bad" cholesterol, is considered a risk factor for a heart attack or stroke because it suggests that arteries are clogged with deposits known as plaque, HDL-C, known as "good" cholesterol, acts like a scavenger, scouring the blood to get rid of excess fat and bad cholesterol. (
  • Healthy levels of HDL-C (above 40 in men, above 50 in women) may protect against heart attacks and strokes, partly due to HDL-C's role in clearing bad cholesterol from the arteries, reducing inflammation and preventing blood clots, whereas low levels of HDL-C have been shown to increase risk. (
  • I like to think of HDL as a vacuum cleaner, picking up cholesterol LDL leaves behind in your arteries. (
  • By contrast, HDL-C tends to carry cholesterol away from the arteries to the liver a process known as reverse cholesterol transport where it is broken down and then eliminated from the body. (
  • An abundance of LDL cholesterol can constrict the arteries of your heart and cause an increased risk of heart attack and stroke. (
  • Good cholesterol, or high-density lipoprotein (HDL), is a natural product of your body that actually carries cholesterol away from your arteries. (
  • If HDL clears the bad cholesterol from the body and keeps the arteries clear, then you would imagine that an increased amount would reduce equate to fewer heart attacks and strokes. (
  • It is important to read the instructions that come with any medications and alert your doctor to any family history of cholesterol related conditions such as atherosclerosis (thinning of the arteries) and heart disease. (
  • But if there are too many particles, problems arise, because the LDL carriers start to store the cholesterol in arteries throughout the body, causing buildup. (
  • So if a cholesterol test measures a high level of LDL particles in your blood, that means too much cholesterol is being moved and stored in your arteries, putting you at risk for heart disease. (
  • Cholesterol travels through the blood on proteins called "lipoproteins. (
  • What is more, two population cohorts reveal that people who experience sleep deprivation may have fewer high-density lipoproteins (HDL) - known as the "good" cholesterol - than those who have sufficient sleep. (
  • Compared with participants who had sufficient sleep, the researchers found that those who experienced sleep loss had reduced expression for genes that encode for lipoproteins - that is, there was reduced activity in genes that are responsible for regulating cholesterol levels. (
  • What you need to know is the status of your high-density lipoproteins (HDLs)--the so-called good cholesterol, according to new recommendations. (
  • Some doctors say people at minimal risk for heart disease need nothing more than a measurement of total blood cholesterol, not more extensive evaluation of HDLs and low-density lipoproteins or LDLs, the so-called bad cholesterol. (
  • High Density Lipoproteins, known as HDL's, are the healthy cholesterol particles that are measured as a part of the total cholesterol level. (
  • A diet rich in EPA and DHA from seafood such as sardines increases your blood's level of high-density lipoproteins, also known as HDL, or "good" cholesterol. (
  • This is because HDL is responsible for transporting low-density lipoproteins -- LDL, or "bad" cholesterol -- to your liver where it is eliminated from your body. (
  • Torcetrapib is a cholesterol ester transfer protein (CETP) inhibitor, a type of drug that increases levels of high-density lipoproteins (HDLs, or "good" cholesterol), Journal of the American Heart Association. (
  • The study found that 6,661 people with type 2 diabetes - also known as "adult-onset" diabetes - showed improved blood sugar control when taking torcetrapib along with a statin medication that reduces low-density lipoproteins (LDLs or "bad" cholesterol). (
  • Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have found new evidence to explain how cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol from "good" high density lipoproteins (HDLs) to "bad" low density lipoproteins (LDLs). (
  • However, despite this intense clinical interest in CETP, little is known concerning the molecular mechanisms of CETP-mediated cholesterol transfers among lipoproteins, or even how CETP interacts with and binds to lipoproteins. (
  • High density lipoproteins (HDL) are the good cholesterol. (
  • Raising your high density lipoproteins (HDL), or the good type of cholesterol, should be a lifelong goal of everyone beginning in their teens. (
  • Two types of lipoproteins carry cholesterol to and from cells. (
  • Cholesterol is transported in the body bound with proteins(lipoproteins). (
  • The names of different kinds of cholesterol are based on density of lipoproteins. (
  • HDL (high-density lipoproteins) also known as "good cholesterol," are packets of protein and fat that deliver fat to specific locations within the body. (
  • There is an increasing effort to create drugs that help to raise levels of HDL working in conjunction with existing drugs that lower "bad cholesterol," or low-density lipoproteins (LDL). (
  • Molecules called high density lipoproteins are important for the transport of cholesterol (collectively known as HDL-C) to the liver for breakdown and removal. (
  • Both kinds of cholesterol travel through your blood as lipoproteins: you can think of them as little packages being sent around your body. (
  • Low-density lipoproteins (LDL) are the "bad" cholesterol. (
  • Cholesterol, like other fats, requires lipoproteins that "carry" fats to and from cells in your body. (
  • The density of these lipoproteins determine if cholesterol is good or bad. (
  • These lipoproteins help in the removal of cholesterol from the cells, which is then transported back to the liver where it is disintegrated and excreted as waste or broken down into parts. (
  • Saturated fats often make up the largest source of cholesterol in a person's diet. (
  • Replacing saturated fats with unsaturated fats can lower your total cholesterol. (
  • Help to reduce levels of LDL-cholesterol restricting foods high in cholesterol and saturated fats (animal foods like seafood, red meat, offal, sausages, animal skin, egg yolk, etc. (
  • Bad cholesterol, the type to worry about, is caused by ingesting foods that are high in saturated fats and cholesterol. (
  • It's so effective that, in a rare harmony of opinion about a natural substance, the Mayo Clinic, the 'New England Journal of Medicine' and the 'Atherosclerosis Journal' all agree that niacin is, "the most effective drug available for raising HDL cholesterol . (
  • Published online in the journal Circulation on September 30, the study results revolve around atherosclerosis, a condition where high levels of cholesterol cause plaques to form in vessel walls, eventually restricting blood flow to cause heart attacks and strokes. (
  • Led by researchers from NYU School of Medicine, this study provides the first direct evidence that raising levels of a simple, functional version of good cholesterol - the HDL protein shuttle that pulls cholesterol out of cells - reversed the progression of atherosclerosis in mice with diabetes. (
  • Our study results argue that raising levels of functional good cholesterol addresses inflammatory roots of atherosclerosis driven by cholesterol buildup beyond what existing drugs can achieve, says study senior author Edward Fisher, MD, PhD, the Leon H. Charney Professor of Cardiovascular Medicine at NYU Langone Health. (
  • Treatments for atherosclerosis for decades have focused on lowering blood levels of LDL or bad cholesterol, a second shuttle that delivers molecules of cholesterol from the diet (and from the liver) to the body's cells, including those in vessel walls. (
  • Diabetes accelerates the development of atherosclerosis, as people with the disease tend to exhibit decreased HDL levels and increased levels of low-density lipoprotein (LDL) cholesterol. (
  • This "bad" cholesterol can build up along the arterial walls and promote atherosclerosis, which can lead to heart attack or stroke. (
  • The researchers found that increasing HDL cholesterol levels in diabetic mice reduced inflammation and helped reverse atherosclerosis. (
  • Our study results argue that raising levels of functional good cholesterol addresses inflammatory roots of atherosclerosis driven by cholesterol buildup beyond what existing drugs can achieve," said senior author Dr. Edward Fisher, a cardiologist and professor at the New York University Grossman School of Medicine . (
  • Results showed that increasing functional HDL cholesterol levels helped reverse atherosclerosis by 30 percent . (
  • Fogelman and his team fed the tomatoes to mice that lack the ability to remove 'bad' low density lipoprotein (LDL) or cholesterol from their blood, and therefore develop inflammation and atherosclerosis when consuming a high-fat diet. (
  • What has previously been known as good cholesterol--high density lipoprotein (HDL)--has now been shown to be not so good in protecting women against atherosclerosis while they are transitioning through menopause, according to a new study from the University of Pittsburgh Graduate School of Public Health that was presented last week at the annual meeting of The North American Menopause Society (NAMS) in Las Vegas. (
  • They reduce bad cholesterol and protect against atherosclerosis or atheroma. (
  • Furthermore tobacco increases the aggressiveness of bad cholesterol, leading to atherosclerosis. (
  • We found that higher levels of HDL cholesterol and HDL particles were both associated with less carotid atherosclerosis, and fewer heart attacks and other cardiovascular events," said Rachel Mackey, Ph.D. , assistant professor of epidemiology at GSPH and lead author of the paper. (
  • Low-density lipoprotein (LDL) particles carry cholesterol to the arterial wall, causing atherosclerosis. (
  • We have found a new and practical way to make a peptide that acts like the main protein in good cholesterol, but is many times more effective and can be delivered by eating the plant," said Alan M. Fogelman, M.D., senior author of the study and executive chair of the Department of Medicine and director of the Atherosclerosis Research Unit in the David Geffen School of Medicine at UCLA. (
  • The rise of cholesterol in the body can give a condition in which excessive cholesterol is deposited in artery walls called atherosclerosis. (
  • In circulation, this antibody binds selectively to the small, dense, oxidized cholesterol or oxysterol rich LDLs that are known to contribute to the development of atherosclerosis. (
  • That said, existing research shows boosting your HDL is good for heart health and may help prevent coronary disease, says Maja Zaric, MD, interventional cardiologist at Lenox Hill Hospital in New York City and a Women's Health advisor. (
  • It takes cholesterol away from the blood and returns it to the liver. (
  • Your liver makes cholesterol, and it is also in some foods, such as meat and dairy products. (
  • It is sometimes called the "good" cholesterol because it carries cholesterol from other parts of your body back to your liver. (
  • Your liver then removes the cholesterol from your body. (
  • HDL (high-density lipoprotein), or "good" cholesterol, absorbs cholesterol and carries it back to the liver. (
  • A research team has uncovered the likely target of niacin ( vitamin B3) in the liver, which should provide a clearer picture of how this vitamin helps maintain adequate HDL-cholesterol levels in the blood and thus lower the risk of heart disease . (
  • This has left researchers grappling with a riddle: Low levels of high-density lipoprotein, or so-called good cholesterol, have long been shown as a predictor of heart disease, since HDLs help ferry bad cholesterol away from artery walls to the liver. (
  • Since the liver already produces a large amount of cholesterol every day, consumption of eggs balances the ratio with the liver's production. (
  • This study suggests that the hormone also encourages the liver to produce HDL cholesterol, the study authors pointed out in a hospital news release. (
  • Good cholesterol or high-density lipoprotein functions to sequester excess cholesterol from the blood and transport them to the liver to be broken down. (
  • Cholesterol is produced by the body (liver) and is essential for normal body functioning. (
  • HDL combs through blood for bad cholesterol, LDL, and flushes it out to your liver for disposal. (
  • To reduce disease risk not addressed by lowering bad cholesterol, the field designed drugs that raised levels of the good cholesterol (HDL) shuttle that carts cholesterol from blood vessel walls to the liver for expulsion from the body. (
  • Does the liver produce more cholesterol when the body is in a rested metabolic state, or when it is slightly excited? (
  • It is like a garbage bag that slowly gets bigger and more spherical as it gathers cholesterol from cells and tissues before depositing them in the liver to be broken down,' said Kris-Etherton, professor at Penn State. (
  • HDL acts as an industrial vacuum by cleaning up low-density lipoprotein (LDL), known as "bad" cholesterol, and transporting it back to the liver where it is broken down and passed out of the body. (
  • Cholesterol is a substance produced from the liver from certain fats in the diet. (
  • Usually if sufficient amount of cholesterol is present in the body, production of new cholesterol particles is suppressed by the liver. (
  • Plants for the liver can help increase good cholesterol. (
  • It is HDL's job to remove the LDL cholesterol from the blood stream, by collecting it up and transporting it to the liver to be reprocessed. (
  • The mutation was preventing the HDL cholesterol from transporting the LDL cholesterol to the liver for reprocessing. (
  • Cholesterol is made in the liver. (
  • These little packages are more dense, and part of their job is to escort cholesterol from other parts of your body back to your liver-where it's then removed. (
  • Once the cholesterol is back in the liver, it's broken down and removed from your body. (
  • These carry cholesterol from your liver to other cells in your body-and therein lies the problem. (
  • Like a fleet of ships, HDL particles carry HDL cholesterol, along with proteins and fats, to the liver where the cholesterol is removed from the body. (
  • Pharmaceutical companies have been developing and testing drugs that raise HDL cholesterol on the theory that more cholesterol will be taken to the liver for removal, rather than for deposition on arterial walls. (
  • HDL removes cholesterol from your bloodstream and carries it back to the liver. (
  • HDL cholesterol (high density lipoprotein) transports the LDL cholesterol to the liver, for it to be reprocessed. (
  • High cholesterol is common in diabetics, people with high blood pressure, people with underactive thyroids and those with liver or kidney disease. (
  • When low-density lipoprotein, or LDL, particles pick up cholesterol, they carry cholesterol from the liver to the other parts of the body. (
  • That's because the HDL particles scavenge excess cholesterol in the blood stream and carry it back to the liver so it can be eliminated from the body. (
  • HDL is a type of cholesterol that actually cleans the blood vessels, as opposed to the LDL cholesterol (aka, bad cholesterol), which clogs them," she says. (
  • Sometimes cholesterol numbers are categorized by the type of cholesterol. (
  • Up until now, doctors have believed HDL cholesterol, long considered the healthy type of cholesterol, could potentially protect a person from coronary heart disease. (
  • Two of the most commonly prescribed drugs for treating HIV (antiretroviral drugs)--nevirapine and efavirenz--can both raise levels of the "good type" of cholesterol (HDL cholesterol), but nevirapine raises it higher than efavirenz, according to a new study by van Leth and colleagues published in the launch issue of PLoS Medicine. (
  • When most people think of cholesterol, they think of the bad, heart-clogging type of cholesterol. (
  • The amount of each type of cholesterol in your blood can be measured by a blood test. (
  • The amount and type of cholesterol the body makes, is usually dependant on genetic and life style factors including the diet consumed in majority of the people. (
  • The risk for developing a heart problem in the coming few years can be worked out for a person, based on age, gender, body weight, blood pressure and even amount and type of cholesterol present. (
  • Individuals who require this type of cholesterol increase may take 1 teaspoon soy lecithin after meals, for example, together with the yogurt. (
  • Kidney beans are bursting with antioxidants and research published last year has linked diets high in antioxidants with raised HDL cholesterol levels. (
  • Cholesterol in the blood can stick to artery walls, forming plaque. (
  • LDL cholesterol can build up, forming plaque on the artery walls and constricting blood flow. (
  • Among patients taking cholesterol-lowering drugs called statins, the higher the HDL or good cholesterol, the less likely they were to have a heart attack or other "cardiovascular event," they found. (
  • The main focus for better cardiovascular health should be on lowering LDL cholesterol - because that's the main culprit. (
  • And this so-called "good" cholesterol, or HDL cholesterol, has been linked to positive effects for cardiovascular health. (
  • A low level of high-density lipoprotein cholesterol (HDL-C) is an independent risk factor for cardiovascular disease, the leading cause of death worldwide, according to background information in the article. (
  • To reduce the risk of cardiovascular disease, doctors recommend lowering the body's levels of bad LDL and increasing levels of good HDL. (
  • A new review addresses the mysteries behind "good" HDL cholesterol and why boosting its levels does not necessarily provide protection from cardiovascular risk for patients. (
  • Historically, HDL cholesterol , or 'good' cholesterol, is thought to be protective at high levels for cardiovascular disease and death," said study lead author Dr. Marc Allard-Ratick, who's with Emory University School of Medicine in Atlanta. (
  • In others words, the so-called 'good' cholesterol in terms of cardiovascular risk could go 'bad' and be associated with excess risk," added Fonarow, who was not part of the team behind the new study. (
  • Patients with very high HDL cholesterol should continue to address other modifiable risk factors -- such as high blood pressure , smoking and obesity -- to reduce cardiovascular disease. (
  • One way to help prevent cardiovascular disease and high cholesterol has been the recommendation to avoid foods high in cholesterol , which includes eggs. (
  • Loading up HDL particles with cholesterol in a bid to lower cardiovascular risk was a mistaken therapeutic strategy, he added. (
  • There are two broad types of cholesterol in the body that are each associated with altered risk of cardiovascular problems: high-density lipoprotein (HDL) and low-density lipoprotein (LDL). (
  • According to the ten-year study carried out on 1,054 American women by Karen Matthews, of the University of Pittsburgh, women's cholesterol levels tend spike after the menopause, placing them at greater risk of cardiovascular events. (
  • Those with basement-level HDL were more likely to die of cardiovascular complications, but the risk did not drop steadily as good cholesterol levels rose. (
  • HDL has been thought to lower cardiovascular risk by cleansing the bloodstream of "bad" cholesterol and scrubbing the inner walls of blood vessels, so your levels of HDL were thought to predict your risk of heart attack or stroke. (
  • Exposure to higher levels of air pollution may increase cardiovascular disease risk by lowering levels of high-density lipoprotein (HDL), commonly known as "good" cholesterol, says a study. (
  • University of Cincinnati (UC) researchers have determined the structure of human HDL cholesterol and say the finding could help explain how this "fat packet" protects against cardiovascular diseases, including heart attack and stroke. (
  • Studies also show that in certain cases dietary cholesterol from eggs may in fact raise the levels of 'good' cholesterol, which could help to protect against cardiovascular disease. (
  • As you can see, cholesterol-and having healthy cholesterol levels-is important to your overall health, especially when you have diabetes and want to avoid cardiovascular complications. (
  • one can look at HDL cholesterol, which is one type of the cargo that is carried on the ship, or one can look at the number of ships," said Samia Mora, M.D., a physician in the Brigham and Women's Hospital Cardiovascular Division and senior author of the paper. (
  • High levels of LDL cholesterol raise your risk for heart disease and stroke. (
  • If you have high LDL cholesterol levels, your health care team may recommend cholesterol-lowering medicine and lifestyle changes to lower your risk for heart disease and stroke. (
  • Heart disease is one of the leading causes of death, and cholesterol is frequently given the blame. (
  • Over the past 60 years, research has repeatedly demonstrated that there's NO correlation between high cholesterol and plaque formation that leads to heart disease. (
  • After researching the science of lipids, cholesterol, heart disease, and nutrition for nearly eight decades, Dr. Fred Kummerow-now nearly 100 years old-has a thing or two to say about the matter. (
  • Dr. Kummerow's work shows that it's not cholesterol that causes heart disease-it's quite safe to eat eggs, for example-rather it's the trans fats that are to blame. (
  • In the war against heart-damaging high cholesterol, a promising weapon has been largely neutralized. (
  • A string of recent clinical studies, including a major Merck & Co. trial that began in 2007 and was canceled last month, have shown medicines that raise 'good cholesterol' to be no more effective at warding off heart disease than widely used 'bad-cholesterol'-cutting drugs alone. (
  • Pfizer Inc. 's well-known statin Lipitor, now generic, reduced the risk of heart attacks by one-third in studies. (
  • But when the 55-year-old retired financial services executive from Cambridge, Mass., reviewed the recent research with Dr. Plutzky, he says they concluded the niacin wasn't doing anything to lower his heart risk and that his cholesterol was well controlled on the statin Crestor. (
  • The recommendation, under consideration by officials at the National Cholesterol Education Program, followed a review of numerous worldwide studies of heart disease. (
  • Locally, physicians say they have routinely ordered measurements of good, bad and total cholesterol when evaluating a patient with known risk factors for heart disease, such as cigarette smoking, high blood pressure, obesity or diabetes. (
  • In general, adults should get an initial cholesterol test at age 20, with follow-up tests scheduled on the basis of results and an individual's risk factors for heart disease. (
  • Raising the levels of good cholesterol helps reduce heart disease risk. (
  • Decades of animal studies and epidemiological data had suggested that raising blood levels of high-density lipoprotein--HDL, or 'good' cholesterol--might have a stronger protective effect against heart disease than statins, drugs that lower levels of low-density lipoprotein ('bad' cholesterol or LDL). (
  • BOSTON (Reuters) - The amount of "good cholesterol" in the blood remains an important marker for heart disease regardless of how much "bad cholesterol" is lowered, researchers said on Wednesday. (
  • Dr. Philip Barter of the Heart Research Institute in Sydney said the result is important because "it shows very, very clearly that the risk is real" when levels of good cholesterol, known as HDL, are too low. (
  • Doctors have known for years that HDL, or high-density lipoprotein, protects against heart attacks and stroke, probably by cleaning up the bad low-density lipoprotein cholesterol, known as LDL. (
  • Barter said aggressively lowering levels of bad cholesterol probably reduces the risk of heart disease and stroke by 40 to 50 percent. (
  • There's a reason HDL cholesterol is called "good" cholesterol: Raising the body's levels of HDL could lower your risk of heart attack and stroke, many scientists and doctors believe. (
  • That idea is supported by years of observational studies and small clinical trials, which show that low levels of HDL cholesterol can lead to a higher risk of heart events. (
  • Here's one approach to lowering cholesterol-and improving heart health-that's been proven over and over again: Diet and exercise. (
  • According to a recent study 2 led by Nick Fuller at the University of Sydney, Australia, and published in the American Journal of Clinical Nutrition, eggs, "despite conflicting evidence continuing around the world," are not responsible for heart disease or high cholesterol . (
  • Backing up the study results, the Australian Heart Foundation notes that "eggs are extremely nutritious (and) contain good quality protein and are a source of healthy fats including omega-3 fats . (
  • There are two types of cholesterol that play a role in heart disease. (
  • While doctors generally say that high cholesterol levels are 'bad', nearly all health professionals and cholesterol researchers agree that high levels of HDL's are actually quite good and tend to be protective against heart disease, stroke and other chronic illnesses. (
  • it's also been shown to reduce 'bad' cholesterol, thin the blood and improve blood flow to the heart: each of which independently has been shown to be an important part of preventing and even treating heart disease. (
  • HYDERABAD -- Dr. Reddy's Laboratories Ltd. said Friday it is developing a drug that boosts good cholesterol, as the Indian company joins global majors working on a new class of medicines to reduce the risk of heart attacks in humans.The drug--a cholesteryl ester transfer protein, or CETP, inhibitor--has completed the first phase of human trials, Chairman Anji Reddy told reporters at the company's headquarters in the southern city of. (
  • Use these smart diet tips to quickly and easily lower your blood cholesterol levels and improve your heart health. (
  • This study shows that if there is not enough HDL to transport cholesterol and other lipids around the body, it can not only increase your risk of heart disease but also affect your memory and may increase your risk of getting Alzheimer's disease. (
  • Economical and versatile, sardines are rich in omega-3 fatty acids, which may help lower your risk of heart disease through their effect on your cholesterol. (
  • A high concentration of HDL is linked to a lower overall blood cholesterol total and a decreased risk of heart disease. (
  • The prevailing theory has been that the higher the levels of HDL in your blood the lower your risk of heart disease, therefore bringing up HDL levels is good for your health. (
  • We all know that cholesterol is the main cause of heart attacks. (
  • Reducing bad cholesterol and increasing the good cholesterol significantly lowers the risk of heart attack. (
  • High levels of HDL protect the heart and blood vessels by reducing LDL cholesterol in blood. (
  • Since there are no symptoms of high cholesterol levels, most people do not know that they are susceptible to heart disease. (
  • If, for example, a woman is normal weight, exercises, and does not have heart risk factors like high LDL cholesterol (the "bad" kind) or diabetes, a high HDL is "probably not something to worry about," El Khoudary said. (
  • The American Heart Association has a primer on blood cholesterol . (
  • Here are some tips for adopting a heart-healthy diet that's designed to keep your cholesterol at optimal levels. (
  • The American Heart Association recommends consuming less than 300 milligrams of cholesterol a day. (
  • The study is the first to show lowering cholesterol may actually reserve the signs of heart disease. (
  • The investigators believe these findings point to the need for further research into optimal levels of LDL cholesterol to lower the risk of heart disease and stroke. (
  • Making an effort to improve your cholesterol will help you reduce risk of heart disease and stroke. (
  • Could Too Much 'Good' HDL Cholesterol Be Bad for Your Heart? (
  • MONDAY, Aug. 27, 2018 (HealthDay News) -- When it comes to protecting one's heart, high-density lipoprotein cholesterol -- or HDL -- has long had a reputation of being the "good" cholesterol, compared to the "bad" cholesterol -- LDL (low-density lipoprotein). (
  • The findings are based on a roughly four-year tracking of cholesterol levels and heart disease among nearly 6,000 men and women. (
  • But the ability of treatments that lower LDL cholesterol to reduce heart attack risk is limited, and especially in adults with diabetes, who are twice as likely to die from heart disease or stroke as people without diabetes, according to the American Heart Association. (
  • The two mechanisms should work together, but much anticipated HDL-raising drugs (e.g. cholesteryl ester transfer protein inhibitors) failed in 2016 clinical trials to reduce the risk of heart attacks beyond what could be accomplished by cholesterol lowering. (
  • Individuals who are concerned about high cholesterol, diabetes, heart disease, and other chronic conditions should discuss their concerns regarding egg intake, diet, and exercise with a knowledgeable healthcare professional and continue to follow the ongoing research in this area. (
  • If you're generally healthy but have a low HDL count and a family history of heart disease, you might want to ask your doctor about OTC cholesterol-boosting medications, says Zaric. (
  • Oily fish contain omega-3 fatty acids which can raise HDL and lower levels of LDL cholesterol according to Heart UK. (
  • Elevated levels of LDL cholesterol and/or reduced levels of HDL cholesterol in human plasma are major risk factors for heart disease. (
  • Since CETP activity can reduce HDL-cholesterol concentrations and CETP deficiency is associated with elevated HDL-cholesterol levels, CETP inhibitors have become a highly sought-after pharmacological target for the treatment of heart disease. (
  • In addition to their heart-healthy benefits, almonds also provide a dose of good fats, vitamin E and fibre,' said Etherton. (
  • Which foods can raise good cholesterol levels and at the same time be healthy for your heart? (
  • Research tells us, however, that seeds do more than just keep hunger at bay, they can also help to maintain lower cholesterol levels , so they are a very heart healthy snack option. (
  • This is why a well-rounded, balanced diet, in combination with a consistent and frequent exercise program, is so very important for a healthy heart. (
  • Dr. Marina Cuchel from the University of Pennsylvania School of Medicine describes her studies of high density lipoprotein, aka HDL or good cholesterol, and discusses why measuring HDL level is not the best way to understand risk of heart disease. (
  • However, a study published Wednesday in The Lancet has found that raising levels of HDL cholesterol may not have any effect on heart disease risk after all. (
  • Using databases of genetic information, the researchers found people who were genetically predisposed to have higher levels of HDL cholesterol had no difference in heart disease risk than those who were not predisposed. (
  • However HDL cholesterol levels of more than 60mg/dl helps to lower the chances of heart disease. (
  • The bad cholesterol (LDL) increases the plaque that causes the heart disease. (
  • It can be said that increase in HDL cholesterol levels is an important step to reduce the chances of heart disease. (
  • Regular aerobic exercise which increases the heart rate will also help to increase HDL cholesterol levels. (
  • Even a slight decrease in HDL cholesterol may lead to the formation of plaque and increase the risk of heart disease. (
  • Ask about medications designed to increase your HDL if you're at high risk for heart disease and need to significantly raise your HDL cholesterol. (
  • Good cholesterol" doesn't lower heart attack risk, the Daily Mail has reported. (
  • A great deal of research has previously suggested that higher levels of "good" HDL cholesterol reduce your risk coronary heart disease, while higher levels of "bad" LDL cholesterol increase your risk of a heart attack. (
  • However, it has been hard to tell whether HDL cholesterol directly reduces coronary heart disease risk as other medical, biological or lifestyle factors could be involved. (
  • To get round this, researchers conducted a complex study to identify genes that raise levels of HDL cholesterol, then looked at whether carrying these genes influenced heart disease risk. (
  • They found that carrying these "HDL cholesterol genes" had no effect on the risk of a heart attack. (
  • From this, the researchers concluded that there is no direct relationship between HDL cholesterol and coronary heart disease and, therefore, that other factors must be involved. (
  • This complex study challenges the commonly held belief that having higher HDL cholesterol will reduce heart attack risk. (
  • However, as it only looked at a particular set of genetic variations, it cannot provide the whole answer and tell us whether HDL cholesterol does or does not affect coronary heart disease, and how this effect might come about. (
  • An important question is whether things that increase HDL cholesterol levels during our lifetime (i.e. after our genetics are determined), such as exercise and certain medications, can then improve our heart disease risk. (
  • LDL cholesterol is often referred to as "bad" cholesterol, as research has found that raised levels of LDL are associated with an increased risk of heart attacks. (
  • Conversely, previous observational studies have tended to show that people with higher levels of HDL ("good") cholesterol have a lower risk of coronary heart disease (CHD). (
  • Broadly speaking, mendelian randomisation analysis looks at whether genetics that determine one factor (such as HDL cholesterol levels) are directly associated with the risk of an outcome (such as heart disease). (
  • Learn more about cholesterol from the American Heart Association . (
  • The findings call into question the benefits of raising good cholesterol, one of the main methods pharmaceutical companies including Eli Lilly & Co. and Whitehouse Station, New Jersey-based Merck are pursuing in their efforts to develop heart drugs. (
  • HDL cholesterol levels around 60 milligrams per deciliters (mg/dL) are considered optimal, while values less than 40 are considered a risk factor for heart disease. (
  • However, the idea that there are "bad" and "good" blood lipids that contribute to heart disease is known as the "lipid hypothesis," or " cholesterol myth . (
  • After all, the American Heart Association says that a person's daily cholesterol levels should be kept lower than 300 mg per day to keep the heart healthy. (
  • In fact, there are "good" types of cholesterol called HDL that protect you from a heart attack. (
  • It may go against all that you know about heart health, but some margarines can actually be good for your heart says a 2009 study done by the McGill University School of Dietetics and Human Nutrition. (
  • But recent research in the United States suggests that the risk of heart disease in women increases dramatically after the menopause, because even good cholesterol becomes harmful. (
  • Patients with high levels of LDL cholesterol have a far higher risk of developing heart disease, and their condition should be closely monitored. (
  • While lowering LDL (bad) cholesterol levels plays an important role in the treatment of heart disease, doctors have long believed that taking active measures to increase HDL levels as well would yield additional benefits. (
  • Walking a course regularly helps lower cholesterol levels, and therefore may decrease the risk of heart disease, the experts concluded. (
  • The low-density lipoprotein fraction of their cholesterol, the so-called "bad" cholesterol associated with higher risk of heart disease, fell by an average of 13.2 milligrams. (
  • However, the level of high-density lipoprotein - so-called "good cholesterol," associated with a lower risk of heart disease, did not change significantly, the report said. (
  • High-fat diet has been linked to high cholesterol and ultimately to heart attacks. (
  • Lowering cholesterol is one of the most common ways to reduce your risk of many dangerous conditions like heart disease, diabetes, and stroke. (
  • What that does is it helps remove cholesterol from the body and helps lower your LDL level and it's these numbers that we consider to be the cornerstone of therapy for treating cholesterol problems and heart disease. (
  • A healthy HDL cholesterol level may protect against heart attack and stroke. (
  • Studies show that low levels of HDL cholesterol increase the risk of heart disease. (
  • A high triglyceride level combined with high LDL (bad) cholesterol or low HDL (good) cholesterol is linked with fatty buildups within the artery walls, which increases the risk of heart attack and stroke. (
  • The drug has not yet been approved by the F-D-A. Dippel says it's important that Iowans understand the impact of heart disease, to which cholesterol can be a significant contributing factor. (
  • Research shows that high levels of high-density lipoprotein (HDL), also known as "good" cholesterol, can protect you against heart disease, heart attacks, and diabetes . (
  • Tomatoes that are genetically engineered to produce a peptide that mimics the actions of 'good' HDL cholesterol could help to reduce heart disease risk factors, suggest researchers. (
  • The research - reported at the American Heart Association's Scientific Sessions 2012 ​ - reveals animal data that for the first time shows consumption of tomatoes genetically engineered to produce a small peptide that mimics the action of HDL cholesterol could reduce plaque build-ups in the blood vessels. (
  • Consumption of the GM tomatoes also resulted in higher activity of an anti-oxidant enzyme associated with good cholesterol and related to a lower risk of heart disease (known as paraoxonase), and decreased levels of a tumour premotor that accelerates plaque build-up (lysophosphatidic acid). (
  • Raising HDL, widely known as good cholesterol, for years has been thought to protect against heart attack and stroke. (
  • Some people with high levels of supposedly "good" cholesterol are at much greater risk of heart disease, a study suggests. (
  • Prof Adam Butterworth, one of the researchers from the University of Cambridge, told the BBC News website: "This is significant because we had always believed that good cholesterol is associated with a lower risk of heart disease. (
  • This is one of the first studies to show that some people that have high levels of 'good' cholesterol actually have a higher risk of heart disease so it challenges our conventional wisdom about whether 'good' cholesterol is protecting people from heart disease or not. (
  • While the researchers have questioned the importance of boosting levels of HDL cholesterol, they insist it still remains a valuable tool for predicting the risk of a heart attack. (
  • Prof Peter Weissberg, the medical director at the British Heart Foundation, said: "This is an important study that sheds light on one of the major puzzles relating to cholesterol and heart disease. (
  • In contrast low density lipoprotein cholesterol(LDL) is considered bad, because it tends to choke blood vessels including those of heart and brain, increasing risk of heart diseases, heart attacks and strokes. (
  • However, HDL, the "good cholesterol," has well-documented benefits in protecting against the hardening process, which can lead to heart attacks and strokes. (
  • A new study out this week in the Journal of the American College of Cardiology finds that boosting HDL, or good cholesterol, doesn't do as much to protect against heart and stroke as doctors have long believed. (
  • A new discovery, from researchers we fund, challenges existing theories of 'good' cholesterol and risk of heart disease. (
  • We found that people carrying a rare genetic mutation causing higher levels of the so-called 'good' HDL-cholesterol are, unexpectedly, at greater risk of heart disease. (
  • This is an important study that sheds light on one of the major puzzles relating to cholesterol and heart disease, which is that despite strong evidence showing HDL-C reduces heart disease risk, clinical trials on the effects of HDL-C-raising drugs have been disappointing. (
  • For some time, we were led to believe that LDL cholesterol was the really bad variety, causing heart attacks, angina, heart disease and stroke. (
  • The studies have established that elevated HDL cholesterol levels are not always good for you, but are they actually connected to heart problems? (
  • Every individual who had this mutated gene also had a very high level of HDL cholesterol as well as an 80% increased risk for heart attack. (
  • This new research indicates that raising HDL levels is not enough, as well as showing us that if someone's HDL count is high it does not necessarily mean that their risk of heart attack is low. (
  • The findings showed that for young individuals, under the age of 50, having abnormally low good cholesterol may increase the risk of heart attack than those with elevated bad cholesterol. (
  • While it is widely known that cholesterol may be bad for the health of the heart, a new study has showed that not having enough good cholesterol can also be bad. (
  • As well as ensuring good bone health and immunity, studies have shown that low levels of vitamin D may be associated with a host of medical conditions including certain cancers, heart disease and multiple sclerosis. (
  • It is widely believed that eggs are a major source of dietary cholesterol, which was once considered a contributory factor to increased risk of heart disease and stroke, but a recent study confirms that this is not the case. (
  • We know omega-3s are important for heart health, but not only can a diet rich in fish with omega-3 fatty acids help to maintain a healthy level of bad cholesterol, it also may give good cholesterol a boost. (
  • This is significant because we had always believed that good cholesterol is associated with a lower risk of heart disease. (
  • Higher than 40 mg/dL for men and higher than 50 mg/dL in women is very good, but if your HDL level is 60 mg/dL or higher, your risk of heart disease will be significantly lower. (
  • (
  • A national team of researchers led by Pitt's Graduate School of Public Health (GSPH) analyzed blood samples of 5,598 healthy men and women and found that when assessing coronary heart disease risk, it appears more beneficial to measure - and make treatment decisions - based on HDL particles, not HDL cholesterol. (
  • RxPG] Researchers have identified a new player in the control of so-called good cholesterol that circulates in the bloodstream and reduces heart attack risk, according to a report in the August issue of Cell Metabolism, a publication of Cell Press. (
  • Should the metabolic pathway uncovered in mice operate similarly in humans, the new discovery could point the way to therapies that protect against heart disease by boosting concentrations of the beneficial high-density lipoprotein cholesterol (HDL-C). (
  • While high levels of "good" cholesterol are associated with heart health benefits, they may not always be as protective in the case of postmenopausal women. (
  • Unlike LDL (referred to as the "bad" type) cholesterol, HDL cholesterol is good for the body as it reduces the risk for heart disease. (
  • The higher concentration of total HDL particles as well as a high number of small HDL particles were found to be beneficial for the heart health of the postmenopausal women. (
  • People on the borderline or people who have a family history of early heart disease - those people might need specialized cholesterol testing," said Dr. Nieca Goldberg, medical director of the Tisch Center for Women's Health at New York University. (
  • Blood cholesterol levels of 240 mg/dL or over should be cause for concern, because at these levels your risk of a heart attack are high. (
  • After 18 months, it was concluded that those who were given the medication to increase HDL cholesterol showed no improvement in risk of heart attack and there was a slight increase in risk of stroke. (
  • HDL cholesterol levels did not have a positive impact on heart disease or stroke. (
  • Previous findings have suggested that elevated levels of saturated fat, found in a wide range of common foods, including meat products, hard cheese, cream and palm oil, can increase the amount of cholesterol in the blood, which increases the chance of developing heart disease. (
  • There are some types of cholesterol which are beneficial to the heart and blood vessels. (
  • researchers found that sleep deprivation may have a negative impact on cholesterol levels. (
  • The researchers say the mechanism linking HDL cholesterol to dementia is unclear but suggest that HDL cholesterol prevents formation of beta-amyloid. (
  • Researchers are now questioning how good, so-called "good" cholesterol really is. (
  • Although the new study from Connecticut researchers indicates that eating whole eggs can be beneficial for people who have metabolic syndrome and not have a negative impact on cholesterol and triglyceride levels, other research has not concurred. (
  • Researchers from Pennsylvania State University in the US compared the levels and function of high-density lipoprotein (HDL) or good cholesterol in people who ate almonds every day, to the HDL levels and function of the same group of people when they ate a muffin instead. (
  • Researchers fed 48 men and women with elevated LDL cholesterol who participated in two six-week diet periods. (
  • At the end of each diet period, the researchers measured the levels and function of each participant's HDL cholesterol. (
  • But according to the researchers at the University of Copenhagen in Denmark, the excess of good cholesterol can also raise risk of death. (
  • In this case, the researchers considered the theory that if increased HDL directly reduces CHD risk, then carriers of genetic variants that confer a high concentration of HDL cholesterol should have a reduced risk of CHD. (
  • Based on the influence that carrying this LIPG variant had on HDL cholesterol levels, the researchers calculated that if the relationship between HDL cholesterol and CHD was causal, then they would expect carriers of this variant to have a 13% reduced risk of CHD. (
  • The researchers have shown that people with extremely high levels of good cholesterol have a higher mortality rate than people with normal levels. (
  • In the study, the researchers compared the cholesterol levels in 417 patients with HIV who were taking nevirapine against 289 patients who were taking efavirenz. (
  • To the researchers' surprise, after the subjects completed fairly vigorous workouts, the participants who had the highest levels of LDL cholesterol had gained the most muscle mass. (
  • Researchers at Cleveland Clinic reported today that administration of a new drug- evacetrapib - can dramatically increase HDL (good) cholesterol, while significantly lowering LDL (bad) cholesterol). (
  • Researchers in the United States have found that hormonal changes in women during the menopause can cause so-called 'good cholesterol' to become dangerous to their health. (
  • The researchers found that "HDL cholesterol can change during the transition period of the menopause. (
  • If your best driving performance is in the golf cart, you may be playing the game wrong: Two researchers say you could do your circulatory system more good if you make the trip on foot. (
  • Ingesting 15 milliliters a day of virgin coconut oil for eight weeks increased high-density lipoprotein (HDL) "good cholesterol" levels in 32 young adults by an average of 5.72 milligrams/deciliter, researchers at Thailand's Chiang Mai University found. (
  • They experienced significant drops in total cholesterol, low-density (LDL) "bad cholesterol" and triglycerides after 90 days, reported Iranian researchers at the Shiraz University of Medical Sciences. (
  • Researchers have found that quitting smoking is clearly associated with an increase in good cholesterol, and the benefits extend far beyond that. (
  • A recent study from researchers in Australia have found that eating foods rich in saturated fat may raise levels of the so-called 'bad' cholesterol (LDL-cholesterol) and actually inhibit the positive action of HDL ('good') cholesterol. (
  • With HDL cholesterol, higher numbers are better, because a high HDL level can lower your risk for coronary artery disease and stroke . (
  • Getting regular exercise can raise your HDL level, as well as lower your LDL. (
  • Compared to those without MS, all the MS patients had lower levels of the cholesterol protein. (
  • Need to lower your cholesterol levels? (
  • Phytosterols are plant cholesterols that can significantly lower cholesterol levels. (
  • What are some foods that lower HDL cholesterol? (
  • Oatmeal, oat bran and other high-fiber foods, fish and foods containing omega-3 fatty acids, nuts, and olive oil can all help lower cholesterol levels, acc. (
  • Can 100% whole grain foods lower cholesterol levels? (
  • But phytosterols help lower cholesterol in people with normal-to-high levels of cholesterol. (
  • With discipline, you can take steps to raise your good HDL cholesterol and lower bad LDL cholesterol. (
  • Good cholesterol is back as therapeutic target because we now understand its biology well enough to change it in ways that lower disease risk. (
  • They found that the increase in functional HDL stopped cholesterol-driven immune cell multiplication (proliferation) in bone marrow, reduced inflammation in immune cells in plaques by half, and enhanced the reversal of atherosclerotic disease processes (regression) by 30 percent in mice already treated to lower their bad cholesterol. (
  • Consuming peanuts on a regular basis may help lower cholesterol levels. (
  • Walnuts are rich in monounsaturates and polyunsaturates, plus they contain decent levels of omega-3 fatty acids, so it comes as no surprise that a study published last year found that participants who ate a handful of walnuts a day had significantly lower LDL readings and higher levels of HDL cholesterol. (
  • Avocados are proven to both lower LDL cholesterol and raise levels of the good stuff. (
  • These foods can raise good cholesterol levels and lower the bad cholesterol in the blood. (
  • The soluble fiber helps lower cholesterol and the insoluble fiber aids in keeping the digestive system regular. (
  • Do you need to raise your HDL or lower your total cholesterol? (
  • To boost functional HDL levels, the team increased the amounts of apolipoprotein A1, an important component of HDL, in diabetic and atherosclerotic mice receiving treatment to lower their LDL cholesterol levels. (
  • Exercising for 30 minutes five times a week can also help improve HDL cholesterol and lower LDL and triglyceride levels. (
  • There are many good foods you can eat to raise your levels of HDL and to lower your "bad" LDL and triglyceride cholesterol. (
  • These types of spreads are called sterol margarines, and when eaten in small amounts on a regular basis, they can lower bad cholesterol. (
  • In fact, people who eat this type of spread one to three times a day may lower their cholesterol by 36 to 39 percent, according to the McGill study. (
  • The Department of Health and Human Services recommends eating a diet high in soluble fiber to lower LDL cholesterol. (
  • Inuit Eskimos have lower bad cholesterol and higher good cholesterol than other cultures, according to a 2001 study done by the CHUL Research Center's Public Health Research Unit published in the "American Journal of Clinical Nutrition. (
  • You may not be aware of all the options available to you in helping to lower your cholesterol, particularly when. (
  • Many drugs on the market can help lower the "bad" cholesterol level. (
  • This one is supposedly able to lower the "bad" cholesterol while raising the "good" cholesterol levels at the same time. (
  • Making modifications to your diet , even after years of unhealthy eating, might help lower your bad cholesterol, improve your good cholesterol, and help you manage your diabetes. (
  • As a supplement, whey protein has been found to lower both LDL and total cholesterol. (
  • The team found that when the mice consumed the tomatoes as 2.2% of a Western-style high-fat those given the 6F modified tomatoes had significantly lower blood levels of inflammation and significantly higher levels of 'good' cholesterol. (
  • There have been huge efforts put into drugs to raise HDL in the hope they have the same impact as statins, which lower the bad cholesterol. (
  • Higher exposure to black carbon, a marker of traffic-related pollution, is significantly associated with a lower "good" cholesterol level, showed the findings published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology. (
  • However, the risk associated with lower HDL cholesterol levels could be explained by other risk factors, such as higher levels of triglycerides. (
  • Doctors give drugs such as statins to help lower cholesterol levels. (
  • A good ratio is 4:1 or lower, but doctors more commonly target individual levels of LDL and HDL. (
  • You can learn more about the top 5 omega 3 sources and how much you need to lower cholesterol here at Health Central. (
  • However, a high-fiber diet does lower LDL cholesterol. (
  • By and large, the medicines now available lower levels of the bad low-density lipoprotein cholesterol [LDL-C], said Weijun Jin of the University of Pennsylvania School of Medicine. (
  • However, treatment methods that would simultaneously lower bad cholesterol and increase good cholesterol have the potential to work even better. (
  • What Food Is Good to Help Lower High Cholesterol? (
  • Nutrition Plant stanol ester Fatty acid Mayo Clinic Cholesterol: Top 5 foods to lower your numbers High cholesterol Important Basics Food Charts Archived 2011-07-01 at the Wayback Machine cholesterol in foods USDA food composition nutrient database High Cholesterol Effects: Normal Cholesterol Levels? (
  • For now, lifestyle changes such as eating a vegetarian, vegan , or low-fat diet may help boost levels of the cholesterol protein, Gardner says. (
  • THURSDAY, Oct. 11 (HealthDay News) -- For overweight people with diabetes , intensive exercise and dieting not only aids weight loss , it can also help train their fat cells to produce a hormone believed to boost production of "good" cholesterol , according to a new study. (
  • Foods that boost good cholesterol levels in the body are those rich in monounsaturated, polyunsaturated and omega-3 fatty acids such as vegetable oils, nuts and olives. (
  • Find out which foods help you boost levels of high-density lipoprotein cholesterol? (
  • Munching on a handful of almonds daily may boost the levels of 'good' cholesterol in the body while simultaneously improving the way it functions, a study claims. (
  • Even as failures in the field pile up, Merck ($MRK) CEO Kenneth Frazier is pushing ahead with a massive development program for a drug to boost HDL or 'good' cholesterol. (
  • There are a few steps that you can take to boost your HDL cholesterol level. (
  • HDL, or high-density lipoprotein cholesterol, acts as the body's waste-disposal system in the blood. (
  • If you lose 6 lbs (2.72 kg), you can increase the good HDL that removes bad low-density lipoprotein cholesterol. (
  • Nearly every consumer story on high-density lipoprotein cholesterol (HDL-C) will include the phrase "good cholesterol. (
  • High-density lipoprotein cholesterol less than or equal to 45 mg/dL. (
  • The fact that HDL ("good") cholesterol helps to "sweep up" LDL ("bad") cholesterol in the bloodstream remains unchanged, of course. (
  • HDL cholesterol is good, then, because it gets the cholesterol out of the bloodstream (too much cholesterol in the blood in hyperlipidemia, remember). (
  • To do so, it clears up the bloodstream by removing the bad cholesterol and cleaning the inner walls of the vessels. (
  • Cholesterol is a fatty substance that is present in your bloodstream and throughout your body's cellular structure. (
  • Cholesterol does not dissolve in your bloodstream. (
  • What is a healthy level of cholesterol in your bloodstream? (
  • A blood test can measure the LDL, HDL, and total cholesterol. (
  • But having too much cholesterol in your blood raises your risk of coronary artery disease . (
  • A blood test can measure your cholesterol levels, including HDL. (
  • When your body has too much LDL cholesterol, the LDL cholesterol can build up on the walls of your blood vessels. (
  • A cholesterol test, or screening, tells your health care provider the levels of LDL and HDL cholesterol in your blood. (
  • According to the panel, 5% to 10% of people given a clean bill of health because their levels fall below the "desirable" level--200 milligrams per deciliter of blood--might actually have unhealthily low levels of good cholesterol. (
  • In general, total cholesterol levels below 200 milligrams per deciliter of blood are considered "desirable. (
  • One, he says, has to do with c-reactive protein (CRP), a marker of inflammation in blood that tends to drop as patients regulate their cholesterol with statins or lifestyle changes. (
  • The effect of cholesterol in our food on the level of cholesterol in our blood is actually quite small. (
  • El Khoudary's team also measured the study participants' levels of HDL "particles" -- which carry HDL cholesterol through the blood. (
  • In contrast, bad cholesterol or low-density lipoprotein transports cholesterol throughout the various tissues and organs of the body where excess cholesterol eventually deposits in blood vessel walls as plaque that causes coronary artery disease. (
  • Experts advise the public to avoid foods rich in saturated and trans fats, which raise LDL cholesterol levels and damage blood vessels. (
  • A total blood cholesterol level that is below 200 mg/dL is considered to be optimal for both women and men, as presented in a guideline at the National Institutes of Health's MedlinePlus. (
  • A lipoprotein panel is a type of blood test used in measuring total cholesterol levels in the body. (
  • There are two types of cholesterol in the blood: high-density lipoprotein, or HDL and low-density lipoprotein, or LDL. (
  • Sydney, July 19 (IANS) A drug designed to improve levels of "good" cholesterol may also help control blood sugar in diabetics who are on cholesterol-lowering drugs. (
  • What you eat may significantly affect the amount of cholesterol in your blood. (
  • High cholesterol levels or hypercholesterolemia in blood can pose a threat to life. (
  • Ask your doctor for a cholesterol blood test. (
  • While in-home cholesterol tests are on the market, they have not yet been as accurate or trustworthy as a basic blood test. (
  • Calculate your total blood cholesterol. (
  • To calculate total blood cholesterol , add your LDL, HDL, and 20 percent of your triglycerides. (
  • Aim for a total blood cholesterol under 200. (
  • Cholesterol is measured in milligrams per deciliter of blood. (
  • Very high blood levels of HDL cholesterol may actually be bad for you. (
  • NEW YORK: Increasing levels of a simplified version of good cholesterol reversed disease in the blood vessels of mice with diabetes, a new study finds. (
  • The United States uses milligrams as the standard for measuring cholesterol, and levels in the blood are expressed as milligrams per deciliter (mg/dl). (
  • In the United States, good cholesterol numbers for the average, healthy person are less than 200 mg per deciliter of blood. (
  • In Canada and many European countries, good cholesterol numbers are those under 5.2 mmol per liter of blood. (
  • Once a person's levels move above 6.2 mmol per liter of blood, his levels of cholesterol are considered high. (
  • Consuming red wine may help increase the levels of good cholesterol in the blood. (
  • When present in your diet in sufficient amounts, they are thought to help with lowering blood cholesterol levels, as well as enhancing the immune response. (
  • Nuts are also beneficial in helping to reduce blood cholesterol levels. (
  • What characterizes it as good or bad is the type of protein that carries it, because to be transported by the blood fat needs a carrier. (
  • In 1960, the average total cholesterol level in adults was 222 milligrams per deciliter of blood (mg/dL). (
  • Have High Blood Cholesterol? (
  • Ask your doctor to perform a blood lipid profile test to determine if your cholesterol numbers are within the normal range. (
  • Carriers of this gene variant had consistently higher levels of HDL (good) cholesterol compared to non-carriers, but no difference in their levels of LDL (bad) cholesterol or other blood fat levels. (
  • It has been accepted wisdom for many years that the more good cholesterol people have in their blood, the better. (
  • In any case, the results of a new study from the University of Copenhagen seriously contradict the assumption that high levels of HDL in the blood are only a good thing. (
  • For example, looking at blood levels of triglyceride and LDL, the 'bad' cholesterol, are probably better health indicators," he notes. (
  • Instead of looking at how much HDL was present in the blood, they looked at how well HDL extracts cholesterol from cells. (
  • The golfers lowered their total cholesterol by an average of 17 milligrams per deciliter of blood, the study said. (
  • Only one-third to one-fourth of blood cholesterol is carried by HDL. (
  • A lipid profile can be ordered by the doctor, which shows levels of total blood cholesterol, HDL and LDL. (
  • One's daily diet should include food substances, which help augment HDL cholesterol levels in the blood. (
  • They also contribute to clogging of blood vessels, raising levels of bad cholesterol, hence should be avoided. (
  • HDL cholesterol also known as " good cholesterol " is a component of the blood that has health benefits. (
  • Vast amounts of time and money have been pumped into the manufacture of HDL cholesterol over the years, in the hope that they would work in a similar manner to statins and dramatically reduce the amount of bad cholesterol in our blood. (
  • HDL-C, known as "good" cholesterol, acts like a scavenger, scouring the blood to get rid of excess fat and bad cholesterol. (
  • We all need some cholesterol in our blood - the fat helps promote healthy cells. (
  • Before we get too far into hyperlipidemia-high cholesterol in the blood-we should have a grounding in what cholesterol is and what it does. (
  • LDL can carry too much cholesterol (more than is needed by the cells), and then cholesterol will build up in the blood. (
  • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adults Treatment Panel III) Executive Summary (pdf). (
  • While walnuts are busy reducing your cholesterol, they also help keep your blood vessels in a healthy state because of the polyunsaturated fatty acids they contain. (
  • As a guideline, your total blood cholesterol level should be less than 200 mg/dL. (
  • Talk to your doctor to obtain an accurate blood cholesterol reading. (
  • Cholesterol is a soft, waxy substance found in the blood stream and in the body's cells. (
  • What makes cholesterol good or bad isn't the molecule itself, but the type of protein particle that is carrying the cholesterol in the blood stream. (
  • If a blood test finds a lot of HDL particles, that means you've got a strong cleanup crew taking care of excess cholesterol. (
  • Some cholesterol medicines , including certain statins , can raise your HDL level, in addition to lowering your LDL level. (
  • Other research has looked at prescribing cholesterol -lowering drugs, known as statins , to increase good cholesterol in MS patients. (
  • To increase your good cholesterol and keep your bad cholesterol as low as possible, the AHA advises healthy adults to consume a 3.5-ounce serving of fish and seafood at least twice a week, with an emphasis on cold-water fish like sardines that have the highest amounts of omega-3 fatty acids. (
  • Certain factors like a sedentary lifestyle, smoking, drinking in excess, diabetes and bingeing on fatty, processed food lead to increase in cholesterol levels. (
  • Foods that contain polyunsaturated fats and monounsaturated fats, as well as those that contain omega-3 fatty acids, are the best bet to raise one's HDL, o. (
  • Omega-3 fatty acids can be found in fatty fish and fish oils, as well as in nuts, seeds, and canola and soybean oils. (
  • Fatty fish is good to eat as it is low in saturated fat. (
  • This fatty acid is one of the good fats and is found in tuna, salmon and halibut. (
  • Cholesterol, which is a fatty substance known as a lipid, plays a vital role in the normal functioning of the body. (
  • Fish, sunflower oil, flaxseed oil and green vegetables contain omega 3 fatty acids which help to increase HDL cholesterol levels. (
  • HDL cholesterol is made up of proteins that form a cage-like structure encapsulating its fatty cargo. (
  • Trans fatty acids , present in processed foods, cause to increase bad cholesterol. (
  • Incorporating healthy omega 3 fatty acids will also improve your total cholesterol to HDL ratio. (
  • LDL (low-density lipoprotein) , sometimes called "bad" cholesterol, makes up most of your body's cholesterol. (
  • HDL got its good name primarily because of its role in reverse cholesterol transport as the body's Roomba®, vacuuming up cholesterol from macrophages. (
  • An active lifestyle increases the body's metabolic pathways and promotes the formation of good cholesterol. (
  • [ 3 ] Back in 2006, a case-control substudy using nuclear magnetic resonance (NMR) spectroscopy revealed that the modest increase in HDL-C masked a higher increase in total HDL particles, particularly the small HDL particles that are relatively cholesterol-poor. (
  • [ 4 ] The authors speculated that "higher numbers of HDL particles might promote greater cholesterol efflux and protection of LDL [low-density lipoprotein] from oxidative changes. (
  • It is the number of HDL particles and not the cholesterol content that is important," he said. (
  • He said the size of different HDL particles or how good they are at transporting may be more important than the overall levels. (
  • When doctors measure cholesterol and report HDL and LDL levels, they are referring to HDL and LDL cholesterol, not to the particles that carry this cholesterol. (
  • HDL cholesterol is only one property of HDL particles. (
  • In our study, we found that the number of HDL particles had stronger cardio-protection than HDL cholesterol. (
  • HDL particles are known to have a variety of functions, including anti-oxidant, anti-inflammatory and anti-thrombotic properties, in addition to reverse cholesterol transport," Dr. Mackey said. (
  • Measuring the concentration of HDL particles, rather than their cholesterol content, may better reflect HDL functionality. (
  • Our study suggests that it's important to not only measure HDL cholesterol, but to experiment with other ways of measurement, such as HDL particles," Dr. Mackey said. (
  • If your HDL levels are too low, that means there aren't enough particles available to help dispose of excess cholesterol. (
  • It finds that while capital flows tend to go to countries that are safer and have better institutions and financial markets, the share of FDI in total flows is not an indication of good health. (
  • Hence, interpreting the rising share of FDI as a sign of good health is unwarranted. (
  • Despite being vilified for decades, dietary cholesterol is understood to be far less detrimental to health than scientists originally thought. (
  • What's not talked about very much, though, is that humans actually NEED cholesterol for good health. (
  • Interestingly, there are different types of cholesterol: 'bad' cholesterol that may be an overall contributor to the arterial plaque that doctors are so concerned about, and 'good' cholesterol that is an overall contributor to good health. (
  • With a slap in the face to the supplement industry, the less safe drug Niaspan is allowed to make a 'Qualified Health Claim' for reducing cholesterol while the supplement industry is NOT allowed to make the same claim about safer over-the-counter niacin! (
  • In any case, even though your doctor isn't likely to tell you about it, niacin is an incredibly safe over-the-counter supplement that has an amazing ability to increase the good HDL cholesterol levels that we all need for good health- just watch out for the flushing. (
  • With over 14 years of experience in health care, she has the unique perspective of being solidly grounded in Conventional Medicine and being well versed in Alternative Medicine. (
  • The team from the French National Institute for Health and Medical Research argue that their findings suggest physicians and patients should be encouraged to monitor levels of HDL cholesterol. (
  • It studied cholesterol levels in 3,673 people taking part in the Whitehall II study - a study which began in 1985 to assess people's long-term health. (
  • Take charge of your health and find out your cholesterol levels. (
  • Does boosting 'good' cholesterol really improve your health? (
  • High cholesterol does not have overt side effects, but it can be devastating on your health. (
  • Most people know that high cholesterol levels present real dangers to a person's health. (
  • All these foods have a high content of saturated fat which can raise your cholesterol level to unhealthy which could lead to some health issues. (
  • In fact, those receiving the flaxseeds did just as well health-wise as those given statin drugs I certainly know which I'd prefer to be takingPhytosterols are not the only food component involved in lowering cholesterol. (
  • This is an interesting study because we've long held that HDL cholesterol and protective from epidemiological studies - and this is looking at if this has been the right course of thought," Dr. Nieca Goldberg, a cardiologist and medical director of the Joan Tisch Center for Women's Health at the NYU Langone Medical Center, told (
  • Moderate consumption of alcohol is good for health. (
  • NEW YORK (Reuters Health) - Low levels of HDL cholesterol, the "good" cholesterol, are associated with poor short-term memory in middle-aged adults, new findings indicate. (
  • The participants were in generally good health, but not physically active, and none of them were participating in a training program. (
  • In fact, low levels of cholesterol can be hazardous to your health . (
  • Antioxidants help prevent oxidation of good cholesterol increasing its lifetime and prolonging its health benefits. (
  • Whereas HDL cholesterol was thought to protect us from these health complaints. (
  • Knowing that cholesterol problems can cause such a negative impact on your health is a good incentive to learn all about cholesterol. (
  • These lifestyle changes are all natural and healthy ways to raise your HDL level, however a sudden rise in cholesterol levels can be a sign of something that may not be as good for your health. (
  • Here are 16 of the best superfoods foods that fight disease and promote good health. (
  • Keep up to date with our latest articles on health, well-being, beauty and skin care. (
  • With a proper diet, adequate exercise, and good advice from your doctor or health care professional, you should have no problem keeping your cholesterol levels in the safe zone. (
  • Although there is still debate over good HDL cholesterol really is, there is no denying that LDL cholesterol is bad for your health and should be limited. (
  • It's essential for good health and serves several functions, including the formation of cell membranes and certain hormones. (
  • This function is essential to good health. (
  • What we found is that, as women transition through menopause, increases in good cholesterol were actually associated with greater plaque buildup," says Dr. Samar El Khoudary, Assistant Professor in Pitt Public Health's Department of Epidemiology who served as the lead author for the study. (
  • High-density (HDL) cholesterol is thought to help scour the. (
  • Newswise - Regular exercise appears to modestly increase levels of high-density lipoprotein, or "good," cholesterol, according to a meta-analysis study in the May 28 issue of Archives of Internal Medicine , one of the JAMA/Archives journals. (
  • High-density lipoprotein, or HDL, is commonly known as the "good" cholesterol. (
  • the good high density lipoprotein (HDL) and the "bad" low density lipoprotein (LDL). (
  • Good cholesterol, on the other hand, is something, which we call the HDL or high density lipoprotein. (
  • The UCLA team genetically engineered tomatoes to produce 6F - a small peptide that mimics the action of ApoA-1, which is the main protein of high density lipoprotein (HDL) or 'good' cholesterol. (
  • Eating olive oil, fish and nuts raises levels of high-density lipoprotein (HDL) - which is more commonly known as good cholesterol. (
  • First, let me say a little about the "good" form of cholesterol, known as high-density lipoprotein (HDL) cholesterol. (
  • PITTSBURGH, July 11, 2012 - New research from the University of Pittsburgh suggests that doubts raised recently about the protective effects of high density lipoprotein (HDL), or "good," cholesterol by a genetic study and several recent clinical trials of HDL-raising drugs could be put to rest by using a better indicator of HDL status. (
  • Now, if cholesterol is picked up by a high-density lipoprotein, or HDL, particle, it's a good thing. (
  • Participants in both groups had increases in HDL cholesterol, decreases in triglycerides, and an improvement in lipid profiles. (
  • After 60 days, significant reductions were seen in total cholesterol, LDL cholesterol, triglycerides, and the ratio of total to HDL cholesterol in both of the groups. (
  • The levels of cholesterol are usually measured in total cholesterol, LDL, HDL, and triglycerides. (
  • There are many different types of cholesterol. (
  • Then I'll talk a little about the different types of cholesterol and finally explain what the numbers ought to be. (
  • If you've ever had your cholesterol tested or read up on the fat-like waxy substance, then you'll know that there are different types of cholesterol. (
  • Nov. 12, 2013 -- A protein found in HDL, or ''good,'' cholesterol may help protect against the effects of multiple sclerosis , according to new research. (
  • "We have found a new and practical way to make a peptide that acts like the main protein in good cholesterol, but is many times more effective and can be delivered by eating the plant," ​said Fogelman. (
  • The initial 'go to work on an egg' campaign in the 50s saw an increase in the consumption of this economical source of protein but was hit by the 'cholesterol hypothesis' of the 60s. (
  • Eating kidney beans several times a week, coupled with not eating much red meat for protein, will help you reduce your cholesterol. (
  • An immunoglobulin protein, anti-cholesterol may be found both in circulation as well as in the digestive tract. (
  • To help understand cholesterol and decrease intake of cholesterol-rich foods, there are a variety of brochures available. (
  • While there are no foods that affect HDL cholesterol, exercise, particularly aerobic exercise, can help to raise it. (
  • Which foods increase your "good" cholesterol? (
  • What foods cause high cholesterol? (
  • What types of foods raise HDL cholesterol levels? (
  • Foods that are 100 percent whole grain are rich in dietary fiber that effectively reduces cholesterol levels. (
  • Cholesterol in foods can raise both total and bad cholesterol. (
  • Buffet meals may contain many foods that are high in cholesterol. (
  • The good news is that there are some foods that can raise your good cholesterol level. (
  • So what foods are good to eat and get those numbers in check? (
  • So what other foods are there that can raise cholesterol? (
  • Nuts and seeds are some foods that can raise cholesterol levels. (
  • These phytosterols are actually extracted and added to processed foods, such as spreads, as an aid in cholesterol-lowering. (
  • Several foods help to increase HDL cholesterol levels. (
  • Eating these types of foods on a regular basis can raise your good cholesterol levels by 15 to 35 percent. (
  • Fiber also keeps the cholesterol in foods from being absorbed into your body. (
  • Women should avoid high cholesterol foods after the menopause. (
  • LDL cholesterol is present in transfats which are present in ready to eat fast foods like chips and animal fat used for cooking. (
  • Other food substances that can increase levels of the bad cholesterol are dairy products like butter and cheese, deep fried foods, ice creams, cakes, meat products other than fish, poultry products, among others. (
  • Cholesterol is formed in our livers and also occurs naturally in a number of foods. (
  • As cholesterol occurs naturally in some foods, you can use your dietary choices to increase HDL levels too. (
  • High HDL cholesterol foods include nuts, fish and olive oil. (
  • Fortunately, there are things you can do to reduce that cholesterol number, including eating certain foods and preparing them in a certain way. (
  • More frequently, you should consider eating foods that are either fat free or low in saturated fat and cholesterol. (
  • This list consists of common foods with their cholesterol content recorded in milligrams per 100 grams (3.5 ounces) of food. (
  • It's not enough to measure total cholesterol levels anymore. (
  • If your total cholesterol still isn't lowered, medication might be prescribed. (
  • In addition, while levels of "bad" LDL cholesterol did not change, levels of the fat hormone adiponectin and HDL cholesterol did increase: Total adiponectin produced by fat cells increased about 12 percent and HDL cholesterol increased nearly 10 percent in the people who made lifestyle changes, compared to those in the control group, the research showed. (
  • The effect of exercise was greater in those who had a higher total cholesterol level (220 milligrams per deciliter or greater) and in those with a body mass index of less than 28. (
  • The new measure, says Fisher, should be how well a person's HDL can pull cholesterol out of cells (total cholesterol efflux), because it better captures the inflammatory part of the disease process. (
  • Usually a total cholesterol below 200 is ideal. (
  • he finds that they help patients realize that total cholesterol alone is not a good metric. (
  • He'll review with you the results of the test, focusing on your total cholesterol, LDL and HDL cholesterol levels. (
  • Ideally, your total cholesterol is below 200 mg/dL and your HDL is above 60 mg/dL. (
  • Therefore a person wishing to be healthy should aim for keeping his total cholesterol in normal range (up to 200-250mg/dl) and have high levels of HDL(ideally 40-60mg. (
  • Apart from diet, regular physical exercise is helpful in keeping total cholesterol within normal range and increasing levels of good cholesterol. (
  • At the end of the four week trial, those in the high monounsaturated fat group had significantly higher HDL levels, and improved ratios of total cholesterol to HDL. (
  • Total cholesterol and LDL ("bad") cholesterol levels were not significantly different between the groups. (
  • As LDL is lowered, your total cholesterol-to-HDL ratio improves. (
  • Lack of exercise, a poor diet (with high amounts of saturated fat), drinking alcohol and smoking are all contributing factors to high levels of total cholesterol and "bad" LDL cholesterol in particular. (
  • There is also a genetic factor at play, and even certain medications can increase your total cholesterol level. (
  • Healthy levels of HDL cholesterol are 60 mg/dL and above. (
  • You can reduce levels of LDL cholesterol in your body by stopping smoking, exercising regularly and adopting a healthy, balanced diet, which is low in saturated fat and packed with LDL cholesterol-lowering staples. (
  • The trendy salad favourite is packed with soluble fibre and plant sterols, which reduce the amount of LDL cholesterol in the body, in addition to monounsaturated fat, which as we know, boosts HDL cholesterol as part of a healthy, balanced diet. (
  • We know that the extensive research done world-wide proves that a healthy diet is most definitely the best line of defense against high cholesterol levels. (
  • This way you'll be sure you are getting the phytosterols as well as the beneficial fiber, minerals and healthy fats. (
  • Experts recommend consuming more healthy fats, such as monounsaturated and polyunsaturated fats, as they help improve HDL cholesterol levels. (
  • A spate of recent worldwide studies reveal several cholesterol-healthy alternatives to olive oil. (
  • Our FREE cholesterol guide will help you understand and manage your cholesterol, so you can take action and live healthy! (
  • An eight week comparison of the investigational drug GW590735, placebo, and the marketed drug fenofibrate intended to increase the levels of 'good cholesterol' and decrease levels of 'bad cholesterol' in healthy patients with low levels of good cholesterol and high levels of bad cholesterol. (
  • Healthy cholesterol levels are situated between 40 - 60mg/dl. (
  • You should maintain a healthy level of cholesterol by undergoing regular cholesterol screening as a part of your yearly doctor visits. (
  • Regular exercise can maintain your cholesterol by burning fat and helping you stay at a healthy body weight. (
  • As well as limiting smoking, drinking and maintaining a healthy weight there are certain things you can do to keep your LDL level low such as exercise and eat food that is rich in fibre (such as oats, sweet potatoes, legumes, beans, fruit and vegetables). (
  • Anti-cholesterol antibodies (ACHA) in patients with different atherosclerotic vascular diseases and healthy individuals. (
  • This fact is not discussed much by the media or by doctors, however, because there is no financial incentive to educate people about HDL cholesterol when the only good ways to raise levels is with diet, exercise- and niacin. (
  • What diet is good for gallstone sufferers? (
  • Alchemy and Crispety- You both make interesting points about the relationship between cholesterol and diet, exercise, and overall lifestyle. (
  • Following this simple diet should keep your cholesterol levels in check. (
  • Also, captions referring to cholesterol intake through diet have no direct relevance to this research, which examined the genetic factors that determine HDL cholesterol levels and not the influence of dietary sources. (
  • Cholesterol levels can be controlled with a strict diet and suitable medication. (
  • More information on cholesterol remedies and diet for cholesterols . (
  • But thats not saying that some fats should be canceled out from the diet, as a matter of fact there are some good fats that our bodies need! (
  • Immunization with cholesterol-rich liposomes induces anti-cholesterol antibodies and reduces diet-induced hypercholesterolemia and plaque formation" (PDF). (
  • Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. (
  • Cholesterol is the waxy substance which is found in all cells of the body. (
  • Cholesterol is a fat-like substance (often, it's referred to as "waxy") that's used by your body to make vitamin D, hormones, and substances that aid in digestion. (
  • Cholesterol is a waxy substance that is found in every single cell in our body. (
  • Do you have high levels of low-density lipoprotein (LDL) cholesterol? (
  • Weight loss also tends to increase good cholesterol, he adds, as does regular exercise. (
  • In fact, eggs increase the HDL or good cholesterol levels in your body. (
  • But it's also a good idea to stock up on superfoods that increase good cholesterol to help regulate your LDL/HDL ratio. (
  • Polyunsaturates, which include sunflower oil, help increase HDL cholesterol but monounsaturated fats such as olive oil are best - a recent study found that extra-virgin olive oil doesn't just increase HDL levels, it improves HDL function, too. (
  • There are several ways to increase the good cholesterol ( HDL) levels naturally. (
  • It is possible to increase the good cholesterol levels naturally by a change in the lifestyle. (
  • Eating half an onion every day helps to increase HDL cholesterol levels by 25 percent. (
  • Soluble fibers help to increase HDL cholesterol levels. (
  • Soy products like tempeh and tofu also help to increase HDL cholesterol levels. (
  • Patients taking nevirapine had a significantly larger increase in HDL cholesterol compared with patients taking efavirenz. (
  • They are rich in omega 3 and help to increase good cholesterol levels. (
  • Scientific studies have shown that these fats not only increase bad cholesterol but also decrease the levels of good cholesterol. (
  • But it has not been clear whether a low HDL cholesterol level would remain a significant risk factor in people whose LDL cholesterol was reduced to very low levels," Barter and colleagues wrote in their report, published in the New England Journal of Medicine. (
  • People with low levels of a form of 'good' cholesterol in middle age may have a higher risk of memory loss and dementia in later life. (
  • At age 55, participants with low HDL cholesterol showed a 27 per cent increased risk of memory loss when compared to those with high HDL. (
  • She added: 'We know that controlling cholesterol in midlife is important if you are to reduce your risk of developing vascular dementia later and this may also be important for the development of Alzheimer's disease. (
  • If you have high cholesterol you should also actively seek treatment from your GP to ensure you are doing everything possible to reduce your risk of dementia in later life. (
  • What is borderline high-risk LDL cholesterol? (
  • However, it is difficult to prove that HDL cholesterol directly lowers people's risk of CHD. (
  • If genetic determinants of HDL cholesterol had no relationship to CHD risk, then there isn't a causal relationship between the two, and other factors are likely to be involved. (
  • Our findings on individuals aged 55 and 61 at the two phases of data collection suggest that low levels of HDL cholesterol may be an important risk factor" for memory loss, Singh-Manoux and colleagues conclude. (
  • In fact, studies in the elderly have shown that those with the lowest levels of cholesterol are at highest risk of death from all causes. (
  • Our body also makes things with cholesterol, like steroid hormones, vitamin D, and bile. (
  • Your body needs some cholesterol to work properly. (
  • His new book, Cholesterol Is Not the Culprit , focuses on the basic chemistry of food, how your body works, and how food fits into the equation. (
  • Soluble fiber makes it more difficult for your body to absorb dietary cholesterol. (
  • [1] Since your body should be able to produce enough cholesterol by itself, that which comes from food should be controlled. (
  • I would also be curious to know when it is that the body makes cholesterol. (
  • Groundnut or peanut oil is another monounsaturated oil that can help elevate levels of HDL cholesterol in the body, and like rapeseed, groundnut oil is suitable for higher temperature cooking. (
  • In fact, a trial conducted in 2015 reported that participants who ate a small portion of unsalted almonds every day had increased the levels of HDL cholesterol in their body by 14% after just six weeks. (
  • Blueberries are an even better source of antioxidants, and like other berries such as raspberries, blackcurrants and strawberries, they help elevate levels of HDL cholesterol in the body. (
  • The soluble fiber binds to bile acid which forms just before any cholesterol is manufactured in the body and then flushes it out. (
  • Cholesterol is a type of fat in the body, important for the formation of cell membranes, sex hormones, cortisol and bile. (
  • It circulates through the body and delivers cholesterol to different tissues and organs. (
  • Cholesterol is a type of fat found in all humans and serves many necessary functions in the body. (
  • Any attempt to remove all the 'bad' cholesterol from your body would cause serious problems. (
  • Extra weight contributes to high cholesterol, but you may be able to reduce your bad cholesterol by losing as little as 5 percent of your body weight. (
  • Good cholesterol is complex, with various particle sizes and subspecies floating around in the body. (
  • As other substances, cholesterol is also needed by the body. (
  • A word of caution here, excess of good cholesterol is also not good for the body. (
  • Moreover if one consumes food promoting good cholesterol, more than what is needed, the extra amount is converted into fat and deposited in the body, contributing to obesity. (
  • Stress may influence the levels of bad cholesterol in the body. (
  • i think polyunsaturated is good and saturated is bad like saturating your body with bad fat! (
  • Your body actually makes most of the cholesterol you need, although you do get some of it from what you eat. (
  • Cholesterol is both produced naturally by your body and ingested when you eat animal products such as meats, poultry, eggs, butter and cheese. (
  • Most of us know that there is good and bad cholesterol in our body. (
  • The human body makes one-eighth to one-fourth teaspoons of pure cholesterol daily. (
  • Flaxeeds are used to to lowering bad cholesterol, raise good cholesterol and also for diabetes. (
  • In the case of the cholesterol they are differentiated by their density. (
  • The bad cholesterol is called LDL-cholesterol (stands for low density lipoprotein). (
  • The soluble fiber contained in oatmeal is what helps reduce the lipoprotein (LDL), which is the low density or unhealthy cholesterol. (
  • When you hear bad cholesterol mentioned, that's low-density lipoprotein (LDL). (
  • Aim for a higher number of good cholesterol (higher than 60 mg/dL but less than 200 mg/dL). (
  • This lowers supplies of the shuttle capable of achieving cholesterol efflux, termed functional HDL. (
  • Flax Seed Lowers Cholesterol: Amaze Your Doctor! (
  • Obesity not only lowers your HDL cholesterol, it raises your LDL cholesterol. (
  • Additionally, apoA1 was shown to enhance arterial relaxation responses, as well as decrease airway hyper-responsiveness and the presence of pulmonary collagen deposition. (
  • smoking, in particular, can decrease HDL cholesterol levels. (
  • High levels of cholesterol can contribute to coronary artery disease, which may cause chest pain and discomfort. (
  • The evidence about cholesterol elevations and coronary artery disease has been widely validated and publicized. (
  • Improving your cholesterol numbers is not only lowering LDLs, but raising HDLs. (
  • Having 'good cholesterol' is a combination of limiting LDLs and increasing HDLs. (
  • The images and structural analyses support the hypothesis that cholesterol is transferred from HDLs to LDLs via a tunnel running through the center of the CETP molecule. (
  • Gang Ren (standing) and Lei Zhang at Berkeley Lab's Molecular Foundry were part of a team that found new evidence to explain how cholesterol is moved from HDLs to LDLs. (
  • Therefore, it maintains HDL levels while still allowing the removal of other cholesterol types, explaining why niacin is especially beneficial. (
  • But even with drugs such as niacin-which raised HDL levels 18 percentage points more than a placebo in an early trial that supported its FDA approval-studies now show it hasn't reduced the odds of falling ill when bad cholesterol is in check. (
  • In higher doses, however, niacin has been shown to be a formidable weapon in the war to RAISE the right kind of cholesterol. (
  • Liposuction is a cosmetic procedure, which is used to suck out the excess or abnormal fat deposition to give a well-contoured shapely look. (
  • NaturalNews) In the past decade doctors have declared an all out war on the high cholesterol levels by prescribing cholesterol lowering 'statin' drugs that have dubious safety records. (
  • About half the group received 30 milligrams of the natural cholesterol lowering statin pravastatin and the other half received 75 milligrams of the new synthetic statin atorvastatin. (
  • Another study found that flaxseeds provide comparable cholesterol-lowering benefits to that of statin drugs. (
  • They compared a daily consumption of 20 grams of ground flaxseed with the effects on cholesterol levels when taking a statin drug. (
  • Together, these data suggest that apoA1 limits pulmonary inflammation and maintains airway physiology, findings that may clarify observations linking abnormal cholesterol and/or apolipoprotein levels with pulmonary irregularities. (
  • But experts said the findings add to evidence that when it comes to HDL, there can be too much of a good thing. (
  • The findings suggested that people with extremely high levels of good cholesterol have a higher mortality rate as compared to people with normal levels. (
  • Findings like lowering bad cholesterol or raising good cholesterol can be called surrogate markers, surrogate endpoints or intermediate endpoints. (