Glucosinolates
Brassica
Brassicaceae
A plant family of the order Capparales, subclass Dilleniidae, class Magnoliopsida. They are mostly herbaceous plants with peppery-flavored leaves, due to gluconapin (GLUCOSINOLATES) and its hydrolysis product butenylisotrhiocyanate. The family includes many plants of economic importance that have been extensively altered and domesticated by humans. Flowers have 4 petals. Podlike fruits contain a number of seeds. Cress is a general term used for many in the Brassicacea family. Rockcress is usually ARABIS; Bittercress is usually CARDAMINE; Yellowcress is usually RORIPPA; Pennycress is usually THLASPI; Watercress refers to NASTURTIUM; or RORIPPA or TROPAEOLUM; Gardencress refers to LEPIDIUM; Indiancress refers to TROPAEOLUM.
Arabidopsis
Oximes
Mustard Plant
Any of several BRASSICA species that are commonly called mustard. Brassica alba is white mustard, B. juncea is brown or Chinese mustard, and B. nigra is black, brown, or red mustard. The plant is grown both for mustard seed from which oil is extracted or used as SPICES, and for its greens used as VEGETABLES or ANIMAL FEED. There is no relationship to MUSTARD COMPOUNDS.
Arabidopsis Proteins
Sinapis
Plant Leaves
Azorhizobium caulinodans
Gene Expression Regulation, Plant
Lepidium
Imidoesters
Oxylipins
Phytochemicals
Manihot
A plant genus of the family EUPHORBIACEAE that is perennial with conspicuous, almost palmate leaves like those of RICINUS but more deeply parted into five to nine lobes. It is a source of a starch after removal of the cyanogenic glucosides. The common name of Arrowroot is also used with Maranta (MARANTACEAE). The common name of yuca is also used for YUCCA.
Anticarcinogenic Agents
Phloem
Plant tissue that carries nutrients, especially sucrose, by turgor pressure. Movement is bidirectional, in contrast to XYLEM where it is only upward. Phloem originates and grows outwards from meristematic cells (MERISTEM) in the vascular cambium. P-proteins, a type of LECTINS, are characteristically found in phloem.
Aphids
Oviposition
Plants, Genetically Modified
Brassica rapa
Butterflies
Cooking
Cytochrome P-450 Enzyme System
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism.
Disease Resistance
Alternaria
Epistasis, Genetic
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
Gene Regulatory Networks
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
Mutation
Transcription Factors
Canada
Encyclopedias as Topic
Beetles
Chlorogenic Acid
Caffeic Acids
Microbial Sensitivity Tests
Conversion of glucosinolates to isothiocyanates in humans after ingestion of cooked watercress. (1/243)
Isothiocyanates (ITCs), major constituents of cruciferous vegetables, can inhibit tumorigenesis in rodents by modulating the metabolism of carcinogens. ITCs that occur as glucosinolates are released by myrosinase-mediated hydrolysis when raw vegetables are chopped or chewed. However, because cruciferous vegetables are commonly consumed by humans after being cooked, it is important to examine whether dietary glucosinolates are converted to ITCs after cooked cruciferous vegetables in which myrosinase is deactivated have been consumed. This information is useful for evaluating the potential role of ITCs in cruciferous vegetables in the protection against human cancers. A urinary marker, based on a cyclocondensation product formed by the reaction of ITCs and their conjugates with 1,2-benzenedithiol, was used to quantify the uptake of dietary ITCs in humans. At breakfast and lunch, nine volunteers consumed a total of 350 g of cooked watercress in which the myrosinase activity was completely deactivated. On the basis of the analysis of ITCs in the cooked watercress upon adding exogenous myrosinase, the amount of glucosinolates ingested by each subject was estimated to be 475 micromol. The 24-h urine samples showed that the total urinary excretion of ITC conjugates in the subjects ranged from 5.6 to 34.8 micromol, corresponding to 1.2-7.3% of the total amount ingested. On the basis of our previous results that approximately 50% of dietary ITCs were excreted in the urine as conjugates, these values represent the minimal in vivo conversion of glucosinolates to ITCs. For purposes of comparison, we carried out a second experiment in which 150 g of uncooked watercress were consumed. The percentage of urinary ITC conjugates excreted in this study ranged from 17.2 to 77.7% of the total ingested ITCs. These results indicate that glucosinolates are converted to ITCs in humans after ingestion of cooked watercress, in which the myrosinase has been completely inactivated. The extent of conversion, however, is considerably less than that after ingesting uncooked vegetables. Furthermore, upon incubation of the cooked watercress juice with fresh human feces under anaerobic conditions, approximately 18% of glucosinolates was hydrolyzed to ITCs in 2 h. These results suggest that the microflora in the intestinal tract are a likely source for the hydrolysis of glucosinolates to ITCs in humans. (+info)An expressional system of human cytochrome P-450 CYP1A1 gene transcription. (2/243)
AIM: To explore an expressional system of human cytochrome P-450 CYP1A1 (CYP1A1) gene transcription. METHODS: The plasmid pMC 6.3 K containing human CYP1A1 promoter was transiently transfected into Hep G2 cells. The expression of chloramphenical acetyltransferase (CAT) reporter gene was detected by ELISA. RESULTS: Both the CAT expression and CYP1A1 activity increased with the concentrations of beta-naphthoflavone from 2.5 to 10 mumol.L-1. At 10 mumol.L-1 of beta-naphthoflavone, the levels of CAT and CYP1A1 were 94-fold and 2.8-fold those of the corresponding control, respectively. Using this method, the study of 8 glucosinolates with various side chains on the induction of CYP1A1 gene transcription showed that none of the parent glucosinolates increased CAT expression, whereas the breakdown products of indol-3-yl-methyl glucosinolate (glucobrassicin), rather than indole-3-carbinol, increased the CAT expression. CONCLUSION: The CYP1A1 gene transcriptional system was more reliable and sensitive. (+info)Glucosinolate genetics and the attraction of the aphid parasitoid Diaeretiella rapae to Brassica. (3/243)
The control of insect pests using parasitoids and carnivores has been successfully applied in protected cropping systems, orchards and forestry. Their success in annual field crops has been more limited due largely to the difficulties of attracting and maintaining a sufficient density of parasitoids in the crop before the levls of the insect herbivores become economically damaging. Parasitoids are known to be attracted to host-plant volatiles; thus, manipulating the host-plant chemistry may provide a means of enhancing the attraction of parasitoids to their prey. In this study we describe the differential attraction of the braconid wasp Diaeretiella rapae to two near-isogenic lines of Brassica oleracea which differ in a gene which alters the chemical structure of the isothiocyanates which are emitted following tissue damage. We demonstrate that, by enhancing the production of but-3-enyl isothiocyanate in B. oleracea and Brassica napus (oilseed rape), we can increase the attraction of D. rapae to these plants under standard field conditions. (+info)Purification and characterisation of epithiospecifier protein from Brassica napus: enzymic intramolecular sulphur addition within alkenyl thiohydroximates derived from alkenyl glucosinolate hydrolysis. (4/243)
Epithiospecifier protein (ESP), a ferrous ion dependent protein, has a potential role in regulating the release of elemental sulphur, nitriles, isothiocyanates and cyanoepithioalkanes from glucosinolates. Two classes of ESP polypeptides were purified with molecular masses of 39 and 35 kDa, and we show that the previously reported instability was conditionally dependent. The 39 kDa polypeptide was made up of two distinct isozymes (5.00, 5.14) whilst several were present for the 35 kDa form of ESP (5.40-5.66). An anti-ESP antibody reacted with both the 39 and 35 kDa ESP forms in Brassica napus and strongly with a polypeptide corresponding to the 35 kDa ESP form in Crambe abyssinica, but did not detect any ESP in Sinapis alba or Raphanus sativus. A cytochrome P-450 mediated iron dependent epoxidation type mechanism is suggested for ESP. (+info)Characterization of glucosinolate uptake by leaf protoplasts of Brassica napus. (5/243)
The uptake of radiolabeled p-hydroxybenzylglucosinolate (p-OHBG) by protoplasts isolated from leaves of Brassica napus was detected using silicone oil filtration technique. The uptake was pH-dependent with higher uptake rates at acidic pH. Imposition of a pH gradient (internal alkaline) across the plasma membrane resulted in a rapid uptake of p-OHBG, which was inhibited in the presence of carbonyl cyanide m-chlorophenylhydrazone, indicating that the uptake is dependent on a proton motive force. Dissipation of the internal positive membrane potential generated a small influx as compared with that seen for pH gradient (DeltapH). Kinetic studies demonstrated the presence of two uptake systems, a saturable and a linear component. The saturable kinetics indicated carrier-mediated translocation with a K(m) of 1.0 mm and a V(max) of 28.7 nmol/microl/h. The linear component had very low substrate affinity. The carrier-mediated transport had a temperature coefficient (Q(10)) of 1.8 +/- 0.2 in the temperature range from 4-30 degrees C. The uptake was against a concentration gradient and was sensitive to protonophores, uncouplers, H(+)-ATPase inhibitors, and the sulfhydryl group modifier p-chloromercuriphenylsulfonic acid. The carrier-mediated uptake system had high specificity for glucosinolates because glucosinolate degradation products, amino acids, sugars, or glutathione conjugates did not compete for p-OHBG uptake. Glucosinolates with different side chains were equally good competitors of p-OHBG uptake, which indicates that the uptake system has low specificity for the glucosinolate side chains. Our data provide the first evidence of an active transport of glucosinolates by a proton-coupled symporter in the plasma membrane of rape leaves. (+info)A glucosinolate mutant of Arabidopsis is thermosensitive and defective in cytosolic Hsp90 expression after heat stress. (6/243)
The TU8 mutant of Arabidopsis previously described to be deficient in glucosinolate metabolism and pathogen-induced auxin accumulation was found to be remarkably less tolerant upon exposure to elevated temperatures than wild-type plants. Although moderately increased temperature only affected shoot growth, exposure to severe heat stress led to a dramatic decay of mutant plants. By contrast, wild-type seedlings showed little or no damage under the same conditions. Analysis of different heat stress proteins (Hsps) in TU8 seedlings revealed that only expression of cytoplasmic Hsp90 was affected in these plants. Although Hsp90 was present under control conditions, its level declined in mutant plants at elevated temperatures. Northern-blot analysis indicated that the decrease in Hsp90 protein was accompanied with a reduction of hsp90 transcript levels. Transient expression of Hsp90 in mutant protoplasts increased their survival rate at higher temperatures to near equivalent that of wild-type protoplasts. These data suggest that the reduced level of Hsp90 in TU8 mutants may be the primary cause for the observed reduction in thermostability. (+info)Cytochrome P450 CYP79B2 from Arabidopsis catalyzes the conversion of tryptophan to indole-3-acetaldoxime, a precursor of indole glucosinolates and indole-3-acetic acid. (7/243)
Glucosinolates are natural plant products known as flavor compounds, cancer-preventing agents, and biopesticides. We report cloning and characterization of the cytochrome P450 CYP79B2 from Arabidopsis. Heterologous expression of CYP79B2 in Escherichia coli shows that CYP79B2 catalyzes the conversion of tryptophan to indole-3-acetaldoxime. Recombinant CYP79B2 has a K(m) of 21 microm and a V(max) of 7.78 nmol/h/ml culture. Inhibitor studies show that CYP79B2 is different from a previously described enzyme activity that converts tryptophan to indole-3-acetaldoxime (Ludwig-Muller, J. , and Hilgenberg, W. (1990) Phytochemistry, 29, 1397-1400). CYP79B2 is wound-inducible and expressed in leaves, stem, flowers, and roots, with the highest expression in roots. Arabidopsis overexpressing CYP79B2 has increased levels of indole glucosinolates, which strongly indicates that CYP79B2 is involved in indole glucosinolate biosynthesis. Our data show that oxime production by CYP79s is not restricted to those amino acids that are precursors for cyanogenic glucosides. Our data are consistent with the hypothesis that indole glucosinolates have evolved from cyanogenesis. Indole-3-acetaldoxime is a precursor of the plant hormone indole-3-acetic acid, which suggests that CYP79B2 might function in biosynthesis of indole-3-acetic acid. Identification of CYP79B2 provides an important tool for modification of the indole glucosinolate content to improve nutritional value and pest resistance. (+info)High resolution X-ray crystallography shows that ascorbate is a cofactor for myrosinase and substitutes for the function of the catalytic base. (8/243)
Myrosinase, an S-glycosidase, hydrolyzes plant anionic 1-thio-beta-d-glucosides (glucosinolates) considered part of the plant defense system. Although O-glycosidases are ubiquitous, myrosinase is the only known S-glycosidase. Its active site is very similar to that of retaining O-glycosidases, but one of the catalytic residues in O-glycosidases, a carboxylate residue functioning as the general base, is replaced by a glutamine residue. Myrosinase is strongly activated by ascorbic acid. Several binary and ternary complexes of myrosinase with different transition state analogues and ascorbic acid have been analyzed at high resolution by x-ray crystallography along with a 2-deoxy-2-fluoro-glucosyl enzyme intermediate. One of the inhibitors, d-gluconhydroximo-1,5-lactam, binds simultaneously with a sulfate ion to form a mimic of the enzyme-substrate complex. Ascorbate binds to a site distinct from the glucose binding site but overlapping with the aglycon binding site, suggesting that activation occurs at the second step of catalysis, i.e. hydrolysis of the glycosyl enzyme. A water molecule is placed perfectly for activation by ascorbate and for nucleophilic attack on the covalently trapped 2-fluoro-glucosyl-moiety. Activation of the hydrolysis of the glucosyl enzyme intermediate is further evidenced by the observation that ascorbate enhances the rate of reactivation of the 2-fluoro-glycosyl enzyme, leading to the conclusion that ascorbic acid substitutes for the catalytic base in myrosinase. (+info)
HAG2/MYB76 and HAG3/MYB29 exert a specific and coordinated control on the regulation of aliphatic glucosinolate biosynthesis in...
Frontiers | Molecular Characterization of MYB28 Involved in Aliphatic Glucosinolate Biosynthesis in Chinese Kale (Brassica...
Nitrile-specifier proteins involved in glucosinolate hydrolysis in Arabidopsis thaliana | Read by QxMD
Frontiers | Unravelling Protein-Protein Interaction Networks Linked to Aliphatic and Indole Glucosinolate Biosynthetic Pathways...
The ecological genetics of aliphatic glucosinolates. - Oxford Big Data Institute
Comparative investigations of the glucosinolate-myrosinase system in Arabidopsis suspension cells and hypocotyls<...
Antimicrobial Activity of Phenolics and Glucosinolate Hydrolysis ...: Ingenta Connect
Development of Brassica Oilseed Crops with Low Antinutritional Glucosinolates and Rich in Anticancer Glucosinolates |...
Arabidopsis Branched-Chain Aminotransferase 3 Functions in Both Amino Acid and Glucosinolate Biosynthesis :: MPG.PuRe
Chemoprotective Glucosinolates and Isothiocyanates of Broccoli Sprouts | Cancer Epidemiology, Biomarkers & Prevention
Influence of the lime on inorganic ion and glucosinolate contents in Chinese cabbage | Korea Science
Antimicrobial activity of phenolics and glucosinolate hydrolysis products and their synergy with streptomycin against...
Arabidopsis IQD1, a novel calmodulin-binding nuclear protein, stimulates glucosinolate accumulation and plant defense
Indole-3-Carbinol | ENCOGNITIVE.COM
Altmetric - Dietary Glucosinolates Sulforaphane, Phenethyl Isothiocyanate, Indole-3-Carbinol/3,3′-Diindolylmethane:...
Biochemical Genetics of Glucosinolate Biosynthesis in Brassica | Springer for Research & Development
Influence of Temperature and Ontogeny - International Specialty Supply
Feeding Tomato and Broccoli Powders - International Specialty Supply
Differential expression of myrosinase gene families
Diet and Vascular Health Study - Full Text View - ClinicalTrials.gov
Myrosinase - Wikipedia
carotenoids | Bonfire
MPI CE: PR Sun 2019
1wcg - Proteopedia, life in 3D
Glucosinolate - Wikipedia
Broccoli: Agricultural Characteristics, Health Benefits and Post-Harvest Processing on Glucosinolate Content (pp. 263-282)
Nourishing Meals®: January 2011
Species-Specific Response of Glucosinolate Content to Elevated Atmospheric CO2 | SpringerLink
HOL2 - Probable thiol methyltransferase 1 - Arabidopsis thaliana (Mouse-ear cress) - HOL2 gene & protein
Publications - University of Copenhagen
21 Glucosinolates Flashcards by Ben Holtom | Brainscape
பரட்டைக்கீரை Kale
Health First Network - FABULOUSLY FERMENTED
September | 2015 | Dr. Ben-Zur, Encino, California
ScienceAsia - Journal of The Science Society of Thailand
More Natures Best Foods
Publication : USDA ARS
Publikationen: Leibniz-Institut für Pflanzenbiochemie
Publikationen: Leibniz-Institut für Pflanzenbiochemie
Non-CCC Clinical Studies - Chemoprotection Center
Nursing Medical Care: Cancer Fighting Foods, Herbs and Spices...
Fighting Breast Cancer with Food - Philadelphia Magazine
LIPANO
Sulforaphanes Protection against CVD | Integrative Wellness Podcast | El Paso, Texas
Kale: Is There Too Much Hype? | Care2 Healthy Living (Page 2)
From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in...
Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. | Cancer...
Joseph Jez | Arts & Sciences
Brassica rebrands SGS glucoraphanin to truebroc | New Hope Network
Isothiocyanates | ENCOGNITIVE.COM
Braised Brussels Sprouts with Sweet Mustard Dressing | Helyns Plant-Based Kitchen
Effects of novel processing techniques on glucosinolates and membrane associated myrosinases in broccoli
Publication : USDA ARS
Inhibition of light-induced stomatal opening by allyl isothiocyanate does not require guard cell cytosolic Ca2+ signaling -...
Super Sprout Broccoli Sprout Powder 70g Digestion & Detoxification 9335946000175 | eBay
Sulforaphane-rich Broccoli Sprout Extract for Autism - Full Text View - ClinicalTrials.gov
Seeking Fit | Broccoli Sprouts - Good Alternatives to Medicine | Page 2
Organic Broccoli Sprout - Corazon Organic Beauty
Glucosinolates Determination in Tissues of Horseradish Plant -BIO-PROTOCOL
DIGITAL.CSIC: Effects of Stir-Fry Cooking with Different Edible Oils on the Phytochemical Composition of Broccoli
Analysis of flavor precursors in radish and radish color extracts
Glucoraphanin And Other Glucosinolates In Heads Of Broccoli Cultivars (pp. 33-46)
Super Sprout Organic Broccoli Sprout Capsules (750mg) x100 | Healthy Being
cell-logic-usa.com - 100% Whole Enzyme Active Broccoli Sprout Powder and superoxide dismutase supplements
China Broccoli Sprout Extract Manufacturers and Suppliers - Factory Wholesale - EO Extract
Plus it
10 Proven Cancer Fighting Foods ~ HealthyAeon
Dietary isothiocyanates as apoptotic inducer for human colorectal cancer (CACO-2) cells | International Journal of Current...
Liver | Natural Solutions Radio
A diet rich in high glucoraphanin broccoli interacts with genotype to reduce discordance in plasma metabolite profiles through...
Side Effects of Broccoli Sprouts | LIVESTRONG.COM
Alfa Aesar™ Acetaldoxime, syn + anti, 98% 250g Alfa Aesar™ Acetaldoxime, syn + anti, 98%
Plus it
Bluebonnet Vitamins - Bluebonnet - Broccoli Active 500mg - 60Vc
Bluebonnet Vitamins - Bluebonnet - Broccoli Active 500mg - 60Vc
Dietary glucosinolates and risk of type 2 diabetes in 3 prospective cohort studies
Dietary glucosinolates and risk of type 2 diabetes in 3 prospective cohort studies
Glucoraphanin - Sulforaphane
Week 6 of Changing an inflammatory phenotype with broccoli sprouts | Surface Your Real Self
Plus it
Plus it
Broccoli (Brassica oleracea italica) - Nutri People
NaturalNewsBlogs Broccoli Sprouts: Natures Most Powerful Cancer-Fighting Food
Broccoli Sprouts: Top 6 Health Benefits for Gut & Hormones
How to Make Broccoli Sprouts | Whole Life Nutrition®
How to Make Broccoli Sprouts | Whole Life Nutrition®
Why broccoli sprouts are good for you | Biohackopedia
A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer - Fingerprint
-...
Chemical Extracted From Broccoli Sprouts May Help Ease Autism Symptoms | IFLScience
Phytosteroid
Glucosinolates. *Precursor to isothiocyanates *Sinigrin. *Gluconasturtiin. *Glucoraphanin. *Aglycone derivatives * ...
Dietary fiber
Glucosinolates. *Precursor to isothiocyanates *Sinigrin. *Gluconasturtiin. *Glucoraphanin. *Aglycone derivatives * ...
Naturally occurring phenols
Glucosinolates. *Precursor to isothiocyanates *Sinigrin. *Gluconasturtiin. *Glucoraphanin. *Aglycone derivatives * ...
Jonathan Gershenzon
Most of the work in his department focuses on two major groups of plant defenses: glucosinolates and terpenoids. National ... doi:10.1038/nature03451 Halkier, B. A., Gershenzon, J. (2006). Biology and biochemistry of glucosinolates. Annual Review of ... The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and influences Trichoplusia ni ...
Rutabaga
Yet, there have been no reports of ill effects in humans from the consumption of glucosinolates from normal amounts of Brassica ... Olsson, K.; Jeppsson, L. (1984). "Undesirable glucosinolates in Brassica vegetables". Acta Hort. 163 (163): 83-84. doi:10.17660 ... "Glucosinolates in Brassica vegetables: The influence of the food supply chain on intake, bioavailability and human health". Mol ... which detects the glucosinolates in rutabaga. Sensitive individuals with the genotype PAV/PAV (supertasters) find rutabaga ...
Black radish
... juice contains glucosinolates. Glucoraphasatin and glucorapanin are the most abundant. Consequently, black radish ...
Myrosinase
Gimsing, A. L.; Kirkegaard, J. A. (2009). "Glucosinolates and biofumigation: fate of glucosinolates and their hydrolysis ... allyl glucosinolate (sinigrin) when in the presence of 500 μM ascorbate.Sulfate, a byproduct of glucosinolate hydrolysis, has ... a gut microbe capable of catalyzing the same hydrolysis of glucosinolates would be able to activate ingested glucosinolates ... crops like rapeseed that contained the glucosinolate-myrosinase system were deliberately bred to minimize glucosinolate content ...
Brassica
T. (January 2002). "Glucosinolates: Bioavailability and Importance to Health". International Journal for Vitamin and Nutrition ... Brassica vegetables provide high amounts of vitamin C, vitamin K, manganese, and soluble fiber, and contain glucosinolates ... Cruciferous vegetables are the dietary source of glucosinolates, a large group of sulfur-containing glucosides. These compounds ... Boiling substantially reduces the levels of broccoli glucosinolates, while other cooking methods, such as steaming, microwaving ...
Antifeedant
ISBN 978-3-527-30673-2. Johnson, I. T (2002). "Glucosinolates: Bioavailability and importance to health". International Journal ... which release pungent oils containing glucosinolates when the plant material is chewed, cut, or otherwise damaged. The odorous ...
Bok choy
... contains glucosinolates. These compounds have been reported to prevent cancer[citation needed] in small doses, but, ...
Diamondback moth
... s are considered pests as they feed on the leaves of cruciferous crops and plants that produce glucosinolates. ... The egg-laying females have been reported to recognize chemicals in the host plants, glucosinolates and isothiocyanates, that ... "Phylloplane location of glucosinolates in Barbarea spp. (Brassicaceae) and misleading assessment of host suitability by a ...
Cabbage
The characteristic flavor of cabbage is caused by glucosinolates, a class of sulfur-containing glucosides. Although found ... Dinkova-Kostova AT, Kostov RV (2012). "Glucosinolates and isothiocyanates in health and disease". Trends Mol Med. 18 (6): 337- ... such as sulforaphane and other glucosinolates. Studies on cruciferous vegetables, including cabbage, include whether they may ...
Red cabbage
Dinkova-Kostova AT, Kostov RV (2012). "Glucosinolates and isothiocyanates in health and disease". Trends Mol Med. 18 (6): 337- ... Such compounds include sulforaphane and other glucosinolates which may stimulate the production of detoxifying enzymes during ...
Mustard oil bomb
The glucosinolate has a β-glucose and a sulfated oxime. The myrosinase removes the β-glucose to form mustard oils that are ... Plant hosts contain a variety of glucosinolates; while all of them have the β-glucose and sulfated oxime. The diamondback moth ... The moth has an enzyme, a sulfatase, that it uses to desulfate the glucosinolate, meaning the myrosinase cannot locate and ... The mustard oil bomb, formerly known as the glucosinolate-myrosinase complex, is a chemical herbivory defense system found in ...
Brassicaceae
In the whites family (Pieridae), one counter mechanisme involves glucosinolate sulphatase, which changes the glucosinolate, so ... Brassicaceae contain glucosinolates as well as myrosinases inside their cells. When the cell is damaged, the myrosinases ... The energy penalty for synthesising all these glucosinolates may be as high as 15% of the total needed to produce a leaf. ... Differences between the mixtures of glucosinolates between species and even within species is large, and individual plants may ...
Cruciferous vegetables
... contain glucosinolates, which are under research for their potential to affect cancer. Glucosinolates ... "Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a ...
Barbarea
Niels Agerbirk & Carl Erik Olsen (2011). "Isoferuloyl derivatives of five seed glucosinolates in the crucifer genus Barbarea". ... Winter cress contains different glucosinolates, flavonoids and saponins. Vera Kuzina; Jens Kvist Nielsen; Jörg Manfred Augustin ... glucosinolates, hairiness and resistance to the herbivore Phyllotreta nemorum". Phytochemistry. 72 (2-3): 188-198. doi:10.1016/ ...
Glucobrassicin
As for other glucosinolates, degradation by the enzyme myrosinase is expected to produce an isothiocyanate, indol-3- ... Glucobrassicin is a type of glucosinolate that can be found in almost all cruciferous plants, such as cabbages, broccoli, ... doi:10.1007/s11101-008-9098-0. Clay, N. K.; Adio, A. M.; Denoux, C.; Jander, G.; Ausubel, F. M. (2009). "Glucosinolate ... Gluconasturtiin Agerbirk, Niels; Vos, Martin; Kim, Jae Hak; Jander, Georg (2008). "Indole glucosinolate breakdown and its ...
Harlequin cabbage bug
As glucosinolates are often used by crucifers to reduce insect herbivory, their sequestration could also reduce attack rates by ... "Sequestration of glucosinolates by harlequin bug Murgantia histrionica". Journal of Chemical Ecology. 28 (9): 1749-62. doi: ...
Kale
Kushad MM, Brown AF, Kurilich AC, Juvik JA, Klein BP, Wallig MA, Jeffery EH (1999). "Variation of glucosinolates in vegetable ... kale contains glucosinolate compounds, such as glucoraphanin, which contributes to the formation of sulforaphane, a compound ... "A mechanistic perspective on process-induced changes in glucosinolate content in Brassica vegetables: A review". Critical ...
Sinapis arvensis
It contains chemicals of the class glucosinolates, including sinalbin. The seeds contain a plant hormone, Gibberellic acid, ... and anionic glucosinolate hydrolysis products in Brassica juncea and Sinapis alba seed extracts using ion chromatography". J ...
پلیفنل - ویکیپدیا، دانشنامهٔ آزاد
Glucosinolates. *Precursor to isothiocyanates *Sinigrin. *Gluconasturtiin. *Glucoraphanin. *Aglycone derivatives * ...
Sulfur assimilation
Glucosinolates are composed of a β-thioglucose moiety, a sulfonated oxime and a side chain. The synthesis of glucosinolates ... The glucosinolate-myrosinase system is assumed to play a role in plant-herbivore and plant-pathogen interactions. Furthermore, ... Upon tissue disruption glucosinolates are enzymatically degraded by myrosinase and may yield a variety of biologically active ... The transfer of a glucose and a sulfate moiety completes the formation of the glucosinolates. The physiological significance of ...
Cauliflower
... including isothiocyanates and glucosinolates. Boiling reduces the levels of cauliflower glucosinolates, while other cooking ... Fenwick, G. Roger; Heaney, Robert K.; Mullin, W. John; VanEtten, Cecil H. (1982). "Glucosinolates and their breakdown products ... Ishida M, Hara M, Fukino N, Kakizaki T, Morimitsu Y (2014). "Glucosinolate metabolism, functionality and breeding for the ... "A Mechanistic Perspective on Process-Induced Changes in Glucosinolate Content in Brassica Vegetables: A Review". Critical ...
Barbarea vulgaris
Glucosinolates such as glucobarbarin and glucobrassicin are used as a cue for egg-laying by female cabbage white butterflies ... A chemotype with deviating glucosinolate content has been described from Western and Central Europe and named the "NAS-type" ( ... van Leur, Hanneke; Raaijmakers, Ciska E.; van Dam, Nicole M. (2006). "A heritable glucosinolate polymorphism within natural ... Agerbirk, Niels; Olsen, Carl Erik (2011). "Isoferuloyl derivatives of five seed glucosinolates in the crucifer genus Barbarea ...
Cyprus
Fenwick, G. Roger; Heaney, Robert K.; Mullin, W. John; VanEtten, Cecil H. (1982). "Glucosinolates and their breakdown products ...
Elizabeth Sattely
Klein, Andrew P.; Sattely, Elizabeth S. (2017-02-21). "Biosynthesis of cabbage phytoalexins from indole glucosinolate". ...
Barbarea australis
With regard to defence chemicals (glucosinolates), it is similar to other members of the genus. Although the plant remains ... "Isoferuloyl derivatives of five seed glucosinolates in the crucifer genus Barbarea". Phytochemistry. 72 (7): 610-623. doi: ...
Erysimum cheiranthoides
Whereas 3-methylsulfinylpropyl glucosinolate and 3-methylsufonylpropyl glucosinolate stimulated oviposition, erysimoside and ... Glucosinolates found in E. cheiranthoides include glucoiberin, glucoerucin, glucocheirolin, and glucoiberverin. Cardenolides ... Pieris rapae tarsal sensilla respond to both glucosinolates and cardenolides, indicating that these compounds are detected on ... Like other Erysimum species, E. cheiranthoides accumulates two major classes of defensive chemicals, glucosinolates and cardiac ...
Sinapine
... glucosinolates in the seeds of Erysimum perofskianum Fisch et Mey., E. Allionii hort., E. crepidifolium Rohb. and E. ...
Elucidating the Role of Transport Processes in Leaf Glucosinolate Distribution | Plant Physiology
indol-3-ylmethyl glucosinolate. 8-MTO. 8-methylthiooctyl glucosinolate. pOHB. para-hydroxybenzyl glucosinolate. LCMS. liquid ... Glucosinolate Analysis. Glucosinolates were analyzed as desulfo-glucosinolates through a modified version of a previously ... Bold values emphasize the contribution of leaf apoplast glucosinolates to total leaf glucosinolates (glucosinolate content in ... we group glucosinolates into total, aliphatic, and indole glucosinolates. Additionally, aliphatic glucosinolates are further ...
Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis ...
Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis ... Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis ... Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis ... Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis ...
The Diversity of Chemoprotective Glucosinolates in Moringaceae ( Moringa spp.) | Scientific Reports
Glucosinolates (GS) are metabolized to isothiocyanates that may enhance human healthspan by protecting against a variety of ... Differences in percentages of the glucosinolates (GS), by glucosinolate, across leaf samples of all species (species ... Table 2 Wilcoxon signed-rank tests for differences in glucosinolate levels between silica-gel dried and fresh, and mature and ... stenopetala). We report on the occurrence of simple alkyl glucosinolates in four species (M. peregrina, M. ruspoliana, M. rivae ...
Glucosinolate - Wikipedia
... glucosinolate". The spelling of a glucosinolate name as one word or two (e.g. allylglucosinolate versus allyl glucosinolate) ... The glucosinolates are also found in seeds of these plants. Glucosinolates constitute a natural class of organic compounds that ... Glucosinolates may alter animal eating behavior. Glucosinolates are studied for their potential to affect plant breeding, plant ... Aromatic glucosinolates include indolic glucosinolates, such as glucobrassicin, derived from tryptophan and others from ...
Analysis of intact glucosinolates by MALDI-TOF mass spectrometry. - PubMed - NCBI
Analysis of intact glucosinolates by MALDI-TOF mass spectrometry.. Botting CH1, Davidson NE, Griffiths DW, Bennett RN, Botting ... Glucosinolates are naturally occurring plant compounds that may be important in the dietary prevention of cancer. This study ... The method was used for crude plant extracts to rapidly examine the glucosinolate profile of the plant. The results for a range ... The methodology was used to characterize a number of individual glucosinolates either produced by synthetic chemistry or ...
Food as Pharma? The Case of Glucosinolates: Ingenta Connect
Glucosinolates and Their Distribution (pp. 9-32)
Neuroprotective Effects of Glucosinolates | SpringerLink
Clarke DB (2010) Glucosinolates, structures and analysis in food. Anal Methods 2:15CrossRefGoogle Scholar ... Glucosinolates Isothiocyanates Sulforaphane Oxidative stress Neurodegeneration Parkinsons disease Alzheimers disease Multiple ... Halkier BA, Gershenzon J (2006) Biology and biochemistry of glucosinolates. Annu Rev Plant Biol 57:303-333CrossRefGoogle ... In: Mérillon JM., Ramawat K. (eds) Glucosinolates. Reference Series in Phytochemistry. Springer, Cham. * First Online 25 April ...
Glucosinolate - Wikipedia
... "glucosinolate". Spelling glucosinolate names in one or two words (e.g. allylglucosinolate versus allyl glucosinolate) are both ... Plants with glucosinolatesEdit. Glucosinolates occur as secondary metabolites of almost all plants of the order Brassicales. ... The essence of glucosinolate chemistry is the ability of a glucosinolate to convert into an isothiocyanate (a "mustard oil") ... Aromatic glucosinolates include indolic glucosinolates, such as glucobrassicin, derived from tryptophan and others from ...
Glucosinolates: Novel Sources and Biological Potential | SpringerLink
... some of the most recent information on glucosinolate-containing plant families is presented. Glucosinolates (GLs) are ... In this chapter, some of the most recent information on glucosinolate-containing plant families is presented. Glucosinolates ( ... Benzoic acid glucosinolate esters and other glucosinolates from Arabidopsis thaliana. Phytochemistry 59(6):663-671. doi: ... Clarke DB (2010) Glucosinolates, structures and analysis in food. Anal Methods 2(4):310-325. doi: 10.1039/B9AY00280D CrossRef ...
The Effects of Glucosinolates in Canola Meal Feeding Regimens on Liver and ... - Yuqiong Wang - Google Books
... detoxification diet glucosinolate levels dietary glucosinolate diets containing effects of canola effects of glucosinolates egg ... rapeseed meal fed the canola feed intake gastrointestinal tract glucosinolate composition glucosinolate content glucosinolate ... products goitrogenic hens fed canola hepatic hepatic GSX individual glucosinolates indole-3-carbinol intact glucosinolates ... The Effects of Glucosinolates in Canola Meal Feeding Regimens on Liver and Thyroid Physiological Responses and Productive ...
Antimicrobial Activity of Phenolics and Glucosinolate Hydrolysis ...: Ingenta Connect
Keywords: Antibacterial drug screening; antibiotic-phytochemicals synergy; glucosinolate hydrolysis products; pathogenic ... Antimicrobial Activity of Phenolics and Glucosinolate Hydrolysis Products and their Synergy with Streptomycin against ... 3 glucosinolate hydrolysis products - allylisothiocyanate, benzylisothiocyanate and 2-phenylethylisothiocyanate) against ...
Frontiers | Glucosinolates are produced in trichomes of Arabidopsis thaliana | Plant Science
We used UPLC/ESI-QTOF-MS to measure the presence of glucosinolates and qRT-PCR to analyse the expression of glucosinolate ... We used UPLC/ESI-QTOF-MS to measure the presence of glucosinolates and qRT-PCR to analyse the expression of glucosinolate ... QTOF-MS analysis of various indolic glucosinolate mutants reveal increased or decreased levels of indolic glucosinolates in ... QTOF-MS analysis of various indolic glucosinolate mutants reveal increased or decreased levels of indolic glucosinolates in ...
Chemoprotective Glucosinolates and Isothiocyanates of Broccoli Sprouts | Cancer Epidemiology, Biomarkers & Prevention
A, glucosinolates are converted to isothiocyanates by the enzymatic action of myrosinase. For glucoraphanin (a glucosinolate) ... Chemoprotective Glucosinolates and Isothiocyanates of Broccoli Sprouts. Theresa A. Shapiro, Jed W. Fahey, Kristina L. Wade, ... Chemoprotective Glucosinolates and Isothiocyanates of Broccoli Sprouts. Theresa A. Shapiro, Jed W. Fahey, Kristina L. Wade, ... those of an equimolar quantity of allyl glucosinolate (9) . A representative tracing and glucosinolate structures are presented ...
Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis | PNAS
glucosinolate;. MAM,. methylthioalkylmalate synthase;. MeJA,. methyl jasmonate.. * Freely available online through the PNAS ... On the basis of the results discussed above, we rename these genes Production of Methionine-Derived Glucosinolate (PMG) 1 and 2 ... Glucosinolates (GSLs) produced by vegetables in the family Brassicaceae, such as broccoli and cabbage, have recently attracted ... One of the intriguing, although poorly described metabolic pathways in plants is the biosynthesis of glucosinolates (GSLs), a ...
Glucoraphanin And Other Glucosinolates In Heads Of Broccoli Cultivars (pp. 33-46)
Notify me of updates to Glucoraphanin And Other Glucosinolates In Heads Of Broccoli Cultivars (pp. 33-46). ... of glucosinolates in broccoli heads harvested from known cultivars grown in field studies. Based on those results, we present ... influencing glucosinolate levels is also considered based on results of studies that have examined this. Breeding approaches ... Glucoraphanin And Other Glucosinolates In Heads Of Broccoli Cultivars (pp. 33-46). $100.00 ...
The phytopathogenic fungus Sclerotinia sclerotiorum detoxifies plant glucosinolate hydrolysis products via an isothiocyanate...
Here, we show that S. sclerotiorum infection activates the glucosinolate-myrosinase system, and isothiocyanates contribute to ... sclerotiorum on glucosinolate-producing plants. Some plants produce toxic isothiocyanates that protect them against pathogens. ... are able to infect many plant hosts including glucosinolate producers. ... Brassicales plants produce glucosinolates and myrosinases that generate toxic isothiocyanates conferring broad resistance ...
Frontiers | The significance of glucosinolates for sulfur storage in Brassicaceae seedlings | Plant Science
The glucosinolate content was not affected by H2S and SO2 exposure, demonstrating that these sulfur compounds did not form a ... The glucosinolate content was not affected by H2S and SO2 exposure, demonstrating that these sulfur compounds did not form a ... The glucosinolate content was decreased in sulfate-deprived plants, though its proportion of organic sulfur fraction was higher ... The glucosinolate content was decreased in sulfate-deprived plants, though its proportion of organic sulfur fraction was higher ...
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response | Science
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response. By Nicole K. Clay, Adewale M. Adio, Carine Denoux ... Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response. By Nicole K. Clay, Adewale M. Adio, Carine Denoux ... Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response Message Subject. (Your Name) has forwarded a page ...
Genetic variation in glucosinolate content within Brassica rapa vegetables
Glucosinolates (GSs) were analyzed in 56 accessions of Brassica rapa grown in the greenhouse. Eight different glucosinolates ... They are the aliphatic glucosinolates progoitrin (PRO), gluconapin (NAP), glucobrassicanapin (GBN), the indolyl glucosinolates ... Genetic variation in glucosinolate content within Brassica rapa vegetables. Author(s). He, H.; Ping, L.; Bonnema, G.; Dekker, M ... The total glucosinolate contents in Brassica rapa group varied substantially between the different accessions. The highest ...
Protection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the...
Protection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the ... Protection of Humans by Plant Glucosinolates: Efficiency of Conversion of Glucosinolates to Isothiocyanates by the ... Protection of Humans by Plant Glucosinolates: Efficiency of Conversion of Glucosinolates to Isothiocyanates by the ... Protection of Humans by Plant Glucosinolates: Efficiency of Conversion of Glucosinolates to Isothiocyanates by the ...
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response | Science
In contrast to mutations that affect the biosynthesis of indole glucosinolates, the aliphatic glucosinolate biosynthetic mutant ... Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response. By Nicole K. Clay, Adewale M. Adio, Carine Denoux ... Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response. By Nicole K. Clay, Adewale M. Adio, Carine Denoux ... The role of glucosinolate hydrolysis in insect resistance has been studied for more than 100 years. Here we have identified a ...
Glucosinolates in Rapeseeds: Analytical Aspects: Proceedings of a Seminar in the CEC Programme of Research on Plant...
The Hardcover of the Glucosinolates in Rapeseeds: Analytical Aspects: Proceedings of a Seminar in the CEC Programme of Research ... Purification and Analysis of Desulfo Indolyl Glucosinolates.- Optimization of Glucosinolates Desulphation before HPL - ... Glucosinolate Analysis in Whole Rapeseed by Near Infrared Reflectance Spectroscopy.- Future Requirements for Glucosinolate ... Approach to Determination of HPLC Response Factors for Glucosinolates.- Isolation of Intact Glucosinolates by Column ...
Glucosinolates do not get destroyed in stir frying | NaturalHealth365
NaturalHealth365) Study reveals that glucosinolates do not get destroyed in the stir frying process. Find out how this nutrient ... Glucosinolates fight cancer by a multitude of actions. Red cabbage and bok choy belong to the Brassica family of vegetables, ... Naturalhealth365) Glucosinolates may not be a word that rolls easily off the tongue. But, the presence of these natural ... Does stir frying destroy the cancer-fighting properties of glucosinolates?. Posted by: Lori Alton, staff writer in Nutrition ...
Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. | Cancer...
Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.. T A ... Isothiocyanates and their naturally occurring glucosinolate precursors are widely consumed as part of a diet rich in ... When plant cells are damaged, glucosinolates are released and converted to isothiocyanates by the enzyme myrosinase. Many ... Finally, when bowel microflora were reduced by mechanical cleansing and antibiotics, the conversion of glucosinolates became ...
Arabidopsis IQD1, a novel calmodulin-binding nuclear protein, stimulates glucosinolate accumulation and plant defense
To uncover regulatory mechanisms of glucosinolate production, we screened Arabidopsis thaliana T-DNA activation-tagged lines ... Glucosinolates are a class of secondary metabolites with important roles in plant defense and human nutrition. ... and identified a high-glucosinolate mutant caused by overexpress … ... Glucosinolates are a class of secondary metabolites with important roles in plant defense and human nutrition. To uncover ...
Pre- and Post-harvest Factors Affecting Glucosinolate Content in Broccoli - Wellness Resources
Rapid Separation of Indole Glucosinolates in Roots of Chinese Cabbage (Brassica rapa Subsp. Pekinensis) by High-Performance...
D. B. Clarke, "Glucosinolates, structures and analysis in food," Analytical Methods, vol. 2, no. 4, pp. 310-325, 2010. View at ... S. F. Vaughn, "Glucosinolates as natural pesticides," in Principles Practices in Plant Allelochemical Interactions, S. J. ... B. A. Halkier and J. Gershenzon, "Biology and biochemistry of glucosinolates," Annual Review of Plant Biology, vol. 57, pp. 303 ... I. E. Sønderby, F. Geu-Flores, and B. A. Halkier, "Biosynthesis of glucosinolates-gene discovery and beyond," Trends in Plant ...
Daily Consumption of Well-Cooked Broccoli May Affect Glucosinolate Metabolites and Inflammatory Biomarkers - Full Text View -...
... is their rich content of glucosinolates. Glucosinolates are sulfur-containing compounds that are converted to isothiocyanates ( ... Daily Consumption of Well-Cooked Broccoli May Affect Glucosinolate Metabolites and Inflammatory Biomarkers. The safety and ... The change in glucosinolate metabolites will be measured in blood plasma and urine [ Time Frame: At end of diet period 1 (week ... The ability of fecal microbiota to metabolize glucosinolates will be determined [ Time Frame: once per week during diet periods ...
ArabidopsisIsothiocyanatesBroccoliBrassicaCruciferous vegetablesAbstractIntact glucosinolatesIndoleMetabolitesBrassicaceaeGlucoraphaninMetabolismDifferent glucosinolatesIndividual glucosinolatesVegetablesIsothiocyanateSulfur compoundsMyrosinasesSinigrinPlantAromatic glucosinolatesDefenseCabbageAllylglucosinolate versus allyl glucosinolateTotal glucosinolate contentsPlantsGenesConcentrationsHerbivoresEnzymeWide variety of glucosinolatesInfluencing glucosinolate levelsAccumulationEnzymesDietaryBiosyntheticSubstance that breaks doNaturally occurring gluConversion of glucosinolatesProperties of glucosinolatesDegradation of glucosinolatesComposition of glucosinolatesAmino acidsGlucobrassicinProgoitrinIndolylCrucifersHigh-performance li
Arabidopsis34
- In Arabidopsis ( Arabidopsis thaliana ), a strategy to defend its leaves against herbivores is to accumulate glucosinolates along the midrib and at the margin. (plantphysiol.org)
- Although it is generally assumed that glucosinolates are synthesized along the vasculature in an Arabidopsis leaf, thereby suggesting that the margin accumulation is established through transport, little is known about these transport processes. (plantphysiol.org)
- Here, we show through leaf apoplastic fluid analysis and glucosinolate feeding experiments that two glucosinolate transporters, GTR1 and GTR2, essential for long-distance transport of glucosinolates in Arabidopsis, also play key roles in glucosinolate allocation within a mature leaf by effectively importing apoplastically localized glucosinolates into appropriate cells. (plantphysiol.org)
- Other distribution patterns have been reported for glucosinolates in an Arabidopsis leaf. (plantphysiol.org)
- To test for epistasis within an adaptive trait genetic network, we generated and tested 47 Arabidopsis thaliana double mutant combinations for 20 transcription factors, which all influence the accumulation of aliphatic glucosinolates, the defense metabolites that control fitness. (plantcell.org)
- Trichomes of Arabidopsis are shown to synthesize chemoprotective aliphatic glucosinolates (AGS) and indolic glucosinolates (IGS), which are known for their biological activities against fungi, bacterial pathogens, or herbivores. (frontiersin.org)
- This signaling starts a cascade that activates a variety of defense responses including callose deposition, programmed cell death, production and accumulation of antimicrobial reactive oxygen species, and induction of phytoalexins and other secondary metabolites such as the indolic antimicrobial compound camalexin (3-thiazol-2′yl-indole) and glucosinolates (1-thio-β- d -glucosides) ( 3 ), which are found in cruciferous plants, including Arabidopsis thaliana . (sciencemag.org)
- To uncover regulatory mechanisms of glucosinolate production, we screened Arabidopsis thaliana T-DNA activation-tagged lines and identified a high-glucosinolate mutant caused by overexpression of IQD1 (At3g09710). (nih.gov)
- Urbancsok J, Bones AM, Kissen R. Glucosinolate-Derived Isothiocyanates Inhibit Arabidopsis Growth and the Potency Depends on Their Side Chain Structure. (mdpi.com)
- Bak S, Tax FE, Feldmann KA, Galbraith DW, Feyereisen R (2001) CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis . (springer.com)
- Campos de Quiros H, Magrath R, McCallum D, Kroymann J, Scnabelrauch D, Mitchell-Olds T, Mithen R (2000) a-Keto acid elongation and glucosinolate biosynthesis in Arabidopsis thaliana . (springer.com)
- Methylthioalkylmalate synthase (MAM) catalyzes the committed step in the side chain elongation of Met, yielding important precursors for glucosinolate biosynthesis in Arabidopsis thaliana and other Brassicaceae species. (nih.gov)
- Indole glucosinolates (IGs) are secondary metabolites found in Brassicaceae plants (including Arabidopsis thaliana ) that have been shown to be effective against T. urticae and could be potential candidates to control spider mites. (uwo.ca)
- Glucosinolate content was analyzed in Arabidopsis wild-type plants in response to single or combinatorial treatments with methyljasmonate (MeJA), 2,6-dichloro-isonicotinic acid, ethylene, and 2,4-dichloro-phenoxyacetic acid, or by wounding. (plantphysiol.org)
- Although green peach aphids (Myzus persicae) are able to avoid most contact with myrosinase when feeding from the phloem of Arabidopsis thaliana, indole glucosinolates are nevertheless degraded during passage through the insects. (ovid.com)
- Here, we identified Far1 Related Sequence (FRS) 7 and FRS12, two transcriptional repressors that accumulate in short-day conditions, as regulators of Arabidopsis glucosinolate (GSL) biosynthesis. (ugent.be)
- GTR-mediated radial import directs accumulation of defensive glucosinolates to sulfur-rich cells (S-cells) in phloem cap of inflorescence stem of Arabidopsis thaliana. (stembook.org)
- This compound has previously been described as a product of myrosinase-mediated breakdown of glucoraphanin, the predominant glucosinolate in Arabidopsis leaves. (rero.ch)
- Taken together, our data suggest that glucosinolate-derived antimicrobial ITCs can play a role in the protection of Arabidopsis against particular pathogens. (rero.ch)
- In Arabidopsis, the functionally similar enzyme, methythiolalkylmalate synthase (MAM), is an important enzyme in the elongation of methionine prior to glucosinolate (GSL) biosynthesis, as part of secondary metabolism. (deepdyve.com)
- The genetic control of concentration and side-chain modification of aliphatic glucosinolates, which have side-chains derived from methionine, are simple and well known from work on Arabidopsis and Brassica crops. (ox.ac.uk)
- Therefore, the genome of Arabidopsis thaliana was selected to be investigated further to identify any putative genes that are potentially involved in the aliphatic glucosinolate biosynthesis pathway, most of its gene are with incomplete annotation. (elsevier.com)
- We investigated, whether the internal breakdown of glucosinolates, a major class of sulfur-containing secondary metabolites, might be an additional component of the carbohydrate starvation response in Arabidopsis thaliana (A. thaliana). (mpg.de)
- When Myzus persicae (green peach aphid) feeds on Arabidopsis aliphatic glucosinolates pass through the aphid gut intact, but indole glucosinolates are mostly degraded. (qxmd.com)
- Although aphid feeding causes an overall decrease in Arabidopsis glucosinolate content, the production of 4-methoxyindol-3-ylmethylglucosinolate is induced. (qxmd.com)
- However, analysis of eds5, pad4, npr1 and NahG transgenic Arabidopsis, which are compromised in this pathway, demonstrated that aphid-induced changes in the indole glucosinolate profile were unaffected. (qxmd.com)
- Together, these results demonstrate that, in response to aphid feeding, Arabidopsis plants convert one indole glucosinolate to another that provides a greater defensive benefit. (qxmd.com)
- Gene expression and glucosinolate accumulation in Arabidopsis thaliana in response to generalist and specialist herbivores of different feeding guilds and the role of defense signaling pathways. (qxmd.com)
- Transcriptional responses of Arabidopsis thaliana ecotypes with different glucosinolate profiles after attack by polyphagous Myzus persicae and oligophagous Brevicoryne brassicae. (qxmd.com)
- We reared B. brassicae on three ecotypes of Arabidopsis thaliana that differ in glucosinolate content and on one genetically transformed line with modified concentrations of aliphatic glucosinolates. (wur.nl)
- Glucosinolates are plant secondary metabolites present in Brassicaceae plants such as the model plant Arabidopsis thaliana. (qxmd.com)
- Characterization of recombinant nitrile-specifier proteins (NSPs) of Arabidopsis thaliana: dependency on Fe(II) ions and the effect of glucosinolate substrate and reaction conditions. (qxmd.com)
- The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and influences Trichoplusia ni herbivory. (qxmd.com)
- Altered glucosinolate hydrolysis in genetically engineered Arabidopsis thaliana and its influence on the larval development of Spodoptera littoralis. (qxmd.com)
Isothiocyanates40
- Glucosinolates (GS) are metabolized to isothiocyanates that may enhance human healthspan by protecting against a variety of chronic diseases. (nature.com)
- Many of the medicinal properties such as cancer treatment, regulation of blood glucose levels, and antibiosis that have long been ascribed to M . oleifera in traditional medicine are likely attributable to its glucosinolates or isothiocyanates 22 . (nature.com)
- In particular, isothiocyanates, the activated form of glucosinolates present in Brassica vegetables, have shown neuroprotective activity in several experimental paradigms due to their peculiar ability to activate the Nrf2/ARE pathway, playing a role in boosting the neuronal natural phase 2 enzyme antioxidant defense system and functioning as a powerful indirect antioxidant. (springer.com)
- This chapter summarizes the preventive glucosinolate-derived isothiocyanates effects in neurodegeneration and underscores the powerful preventive role that these compounds play in assisting the body to help fend off a variety of neurodegenerative diseases. (springer.com)
- Fahey JW, Zalcmann AT, Talalay P (2001) The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. (springer.com)
- Broccoli sprouts are a rich source of glucosinolates and isothiocyanates that induce phase 2 detoxication enzymes, boost antioxidant status, and protect animals against chemically induced cancer. (aacrjournals.org)
- Glucosinolates are hydrolyzed by myrosinase (an enzyme found in plants and bowel microflora) to form isothiocyanates. (aacrjournals.org)
- We studied the disposition of broccoli sprout glucosinolates and isothiocyanates in healthy volunteers. (aacrjournals.org)
- Dosing preparations included uncooked fresh sprouts (with active myrosinase) as well as homogenates of boiled sprouts that were devoid of myrosinase activity and contained either glucosinolates only or isothiocyanates only. (aacrjournals.org)
- In a crossover study, urinary dithiocarbamate excretion increased sharply after administration of broccoli sprout glucosinolates or isothiocyanates. (aacrjournals.org)
- These studies indicate that isothiocyanates are about six times more bioavailable than glucosinolates, which must first be hydrolyzed. (aacrjournals.org)
- In intact plants, sulforaphane and other isothiocyanates are stored as inert precursors, termed glucosinolates. (aacrjournals.org)
- A , glucosinolates are converted to isothiocyanates by the enzymatic action of myrosinase. (aacrjournals.org)
- Brassicales plants produce glucosinolates and myrosinases that generate toxic isothiocyanates conferring broad resistance against pathogens and herbivorous insects. (nature.com)
- Here, we show that S. sclerotiorum infection activates the glucosinolate-myrosinase system, and isothiocyanates contribute to resistance against this fungus. (nature.com)
- For example, plants of the order Brassicales produce amino acid-derived glucosinolates (GLs) which are activated by β-thioglucoside glucohydrolase enzymes (myrosinases) upon tissue damage to produce toxic isothiocyanates (ITCs) and nitriles 5 . (nature.com)
- Protection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora. (nih.gov)
- All Brassica vegetables are rich in sulfur-containing glucosinolates - which break down into biologically active isothiocyanates, including sulforaphane (more about sulforaphane's amazing abilities later). (naturalhealth365.com)
- Isothiocyanates from glucosinolates have been found to protect cell DNA against potentially cancer-causing mutations, and to cause apoptosis - or programmed cell death - in cancer cells. (naturalhealth365.com)
- Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. (aacrjournals.org)
- Isothiocyanates and their naturally occurring glucosinolate precursors are widely consumed as part of a diet rich in cruciferous vegetables. (aacrjournals.org)
- When plant cells are damaged, glucosinolates are released and converted to isothiocyanates by the enzyme myrosinase. (aacrjournals.org)
- As a prerequisite to understanding the mechanism of the protective effects of these compounds, which is thought to involve the modulation of carcinogen metabolism by the induction of phase 2 detoxication enzymes and the inhibition of phase 1 carcinogen-activating enzymes, we examined the fate of ingested isothiocyanates and glucosinolates in humans. (aacrjournals.org)
- Recently developed novel methods for quantifying isothiocyanates (and glucosinolates after their quantitative conversion to isothiocyanates by purified myrosinase) and their urinary metabolites (largely dithiocarbamates) have made possible a detailed examination of the fates of isothiocyanates and glucosinolates of dietary crucifers. (aacrjournals.org)
- First, in nonsmokers, urinary dithiocarbamates were detected only after the consumption of cruciferous vegetables and condiments rich in isothiocyanates and/or glucosinolates. (aacrjournals.org)
- These results establish that humans convert substantial amounts of isothiocyanates and glucosinolates to urinary dithiocarbamates that can be easily quantified, thus paving the way for meaningful studies of phase 2 enzyme induction in humans. (aacrjournals.org)
- Glucosinolates are sulfur-containing compounds that are converted to isothiocyanates (ITC) by an enzyme in the plant called myrosinase, which is released when the vesicles containing myrosinase are ruptured by chewing or cutting. (clinicaltrials.gov)
- Isothiocyanates (ITCs), the biologically important glucosinolate breakdown products, can present health-promoting effects, play an important role in plant defense and affect plant cellular mechanisms. (mdpi.com)
- Isothiocyanates and other glucosinolate-derived compounds can also reduce palatability of the meal. (springer.com)
- Naturally-occurring glucosinolates and their derivative isothiocyanates (ITCs), generated as a result of their enzymatic degradation catalysed by myrosinase, have been linked to low cancer incidence in epidemiological studies, and in animal models isothiocyanates suppressed chemically-induced tumorigenesis. (waocp.org)
- Thus, edible plants belonging to the family Cruciferae and genus Brassica (e.g., broccoli and cauliflower) contain substantial quantities of isothiocyanates (mostly in the form of their glucosinolate precursors) some of which (e.g., sulforaphane or 4-methylsulfinylbutyl isothiocyanate) are very potent inducers of phase 2 enzymes. (pnas.org)
- Glucosinolates and isothiocyanates can be efficiently extracted from plants, without hydrolysis of glucosinolates by myrosinase, by homogenization in a mixture of equal volumes of dimethyl sulfoxide, dimethylformamide, and acetonitrile at −50°C. Extracts of 3-day-old broccoli sprouts (containing either glucoraphanin or sulforaphane as the principal enzyme inducer) were highly effective in reducing the incidence, multiplicity, and rate of development of mammary tumors in dimethylbenz( a )anthracene-treated rats. (pnas.org)
- Glucosinolates and their breakdown derivatives (metabolites), especially isothiocyanates and indole-3-carbinol and sulphoraphane, exert a variety of biological activities that may be the most relevant to healthy longevity activation and disease prevention in humans. (happinessmedicine.com)
- 1998). The anticarcinogenic activity is most likely to be due to activity of the isothiocyanates iberin and sulforaphane derived, respectively from 3-methylsulphinylpropyl (3-MSP) and 4-methylsulphinylbutyl (4-MSB) glucosinolates that accumulate in the florets of broccoli. (biotecharticles.com)
- If you are looking for basic background information about glucosinolates, isothiocyanates, and basic metabolism of sulfur compounds in cruciferous vegetables, please see our articles Eating Healthy with Cruciferous Vegetables and Feeling Great with Cruciferous Vegetables . (whfoods.org)
- This enzyme is found in the cells of cruciferous vegetables and other plants, and it is able to take certain sulfur-containing molecules in cruciferous vegetables called glucosinolates and convert them into related sulfur-containing molecules called isothiocyanates. (whfoods.org)
- It's important to note here, however, that fresh uncut cruciferous vegetables contain both glucosinolates and isothiocyanates, such that we are able to get both sulfur-containing compounds even in the absence of any myrosinase activity. (whfoods.org)
- And it is also important to mention that both glucosinolates and isothiocyanates have been determined to provide us with unique health benefits. (whfoods.org)
- The act of cutting into a fresh cruciferous vegetable and its cells can definitely trigger activation of myrosinase , and so it is possible for glucosinolates to get converted into isothiocyanates through cutting, slicing, chopping, dicing, etc. (whfoods.org)
- The degradation of glucosinolates is catalyzed by thioglucosidases called myrosinases and leads by default to the formation of isothiocyanates. (qxmd.com)
Broccoli32
- Glucosinolates occur in various edible plants such as cabbage (white cabbage, Chinese cabbage, broccoli), Brussels sprouts, watercress, horseradish, capers, and radishes where the breakdown products often contribute a significant part of the distinctive taste. (wikipedia.org)
- Tian M, Xu X, Liu Y, Xie L, Pan S (2016) Effect of Se treatment on glucosinolate metabolism and health-promoting compounds in the broccoli sprouts of three cultivars. (springer.com)
- Glucosinolates (GSLs) produced by vegetables in the family Brassicaceae, such as broccoli and cabbage, have recently attracted considerable attention, because they apparently provide anticarcinogenic, antioxidative, and antimicrobial activity ( 1 - 3 ). (pnas.org)
- This chapter summarizes the results of studies that have examined the concentrations of glucosinolates in broccoli heads harvested from known cultivars grown in field studies. (novapublishers.com)
- Lastly, broccoli seed, which has been shown to contain high levels of glucoraphanin and also glucoiberin, is examined as a potential valuable source for delivery of these glucosinolates. (novapublishers.com)
- Moreover, the quantities of dithiocarbamates excreted were related to the glucosinolate/isothiocyanate profiles of the cruciferous vegetables administered (kale, broccoli, green cabbage, and turnip roots). (aacrjournals.org)
- Glucosinolates (GLs) are the main bioactive compounds found in broccoli (Brassica oleracea L. var. (wellnessresources.com)
- The objectives of the study are 1) to determine the influence of daily consumption of well-cooked broccoli on plasma and urinary glucosinolate metabolites, and 2) to determine inflammatory marker changes consistent with decreased cancer risk. (clinicaltrials.gov)
- Brassica vegetables are a good source of many nutrients, but the unique characteristic of Brassicas (Broccoli in particular) is their rich content of glucosinolates. (clinicaltrials.gov)
- The aim of this study is to investigate how daily consumption of broccoli with myrosinase inactivated by cooking influences glucosinolate metabolism and absorption, and consequent regulation of inflammatory markers. (clinicaltrials.gov)
- Horseradish has 10 times more glucosinolate than broccoli does, and it can contain as many as eight different kinds of glucosinolates. (naturalnews.com)
- The study, published in the journal Plant Foods for Human Nutrition, found that s tir-frying is the best way to preserve the disease-fighting compounds called glucosinolates , which are found in cruciferous vegetables like broccoli. (naturalnews.com)
- Cruciferous vegetables, such as broccoli , Brussels sprouts , cabbage, and kale , are rich in various nutrients such as glucosinolates, which offer various health benefits . (naturalnews.com)
- Effect of water content and temperature on glucosinolate degradation in broccoli (Brassica oleracea var. (wur.nl)
- The effect of watercontent and temperature on glucosinolate thermal degradation in broccoli (Brassicaoleraceavar. (wur.nl)
- Glucosinolates are a group of sulfur-containing glycosides found in many plant species, including cruciferous vegetables such as broccoli, cabbage, brussels sprouts, and cauliflower. (altmetric.com)
- OncoProtect ES "Extra Strength" is an advanced antioxidant formula utilizing a patented process to extract glucoraphanin (sulforaphane glucosinolate or SGS) from its most concentrated cruciferous source - broccoli seeds. (heartburnreliefprix.com)
- Unexpectedly, 3-day-old sprouts of cultivars of certain crucifers including broccoli and cauliflower contain 10-100 times higher levels of glucoraphanin (the glucosinolate of sulforaphane) than do the corresponding mature plants. (pnas.org)
- Notably, sprouts of many broccoli cultivars contain negligible quantities of indole glucosinolates, which predominate in the mature vegetable and may give rise to degradation products (e.g., indole-3-carbinol) that can enhance tumorigenesis. (pnas.org)
- Actually if you can love horseradish like I do, it has 10 fold more glucosinolates than broccoli. (areavoices.com)
- Sprouted broccoli seeds have very high levels of glucoraphanin, a glucosinolate precursor to sulforaphane (10). (alphawolfnutrition.com)
- Commercial freezing processes and storage of high glucosinolate broccoli maintains the high level of glucosinolates compared to standard cultivars, although the blanching process denatures the endogenous myrosinase activity. (biotecharticles.com)
- Meanwhile, glucosinolates are among the most distinctive nutraceutical compounds in cruciferous vegetables, including broccoli. (imedpub.com)
- A glucosinolate is an inert sulfur-containing phytochemical that is most notably found in cruciferous vegetables like Brussels sprouts , broccoli , and cabbage. (theepochtimes.com)
- Glucosinolate is an anticarcinogenic plant substance found in vegetables belonging to the cabbage family, which includes broccoli. (livestrong.com)
- Research published in a 2009 issue of the 'Journal of Zhejiang University Science ' found that cooking broccoli in a microwave results in the highest glucosinolate loss: 60 percent -- compared with 55 percent, 54 percent, and 41 percent, respectively, in stir-fried, stir-fried and boiled and boiled broccoli. (livestrong.com)
- Specific focus was given to effects of HP/HT and PEF processing on the content of glucosinolates and activities of myrosinase isoenzymes (EC.3.2.1.147) in the broccoli preparations. (udl.cat)
- Certain conditions applied in HP/HT processing of broccoli florets were able to maintain a high level of intact glucosinolates. (udl.cat)
- Treatment at 700 MPa and 20 degrees C for 10 min was found to inactivate myrosinase activity, but also pressure treatments at 300 MPa and 20 degrees C were able to maintain a high level of intact glucosinolates present in the untreated broccoli florets. (udl.cat)
- PEF processing of broccoli puree and juice showed that the myrosinase activities resulted in nearly total glucosinolate transformations as result of autolysis during pureeing and juice making prior to the PEF processing. (udl.cat)
- Glucosinolates in the nutrition are very important molecules and widely found in Brassicaceae species (brussels sprouts, Dijon mustard, broccoli, cress etc. (mendeley.com)
- If you're looking for anti-cancer phytochemicals called glucosinolates, you'll find them only in cruciferous vegetables such as broccoli, Brussels sprouts and cauliflower. (theglobeandmail.com)
Brassica18
- Brassica juncea seedlings contained a twofold higher glucosinolate content than B. rapa and these secondary sulfur compounds accounted for up to 30% of the organic sulfur fraction. (frontiersin.org)
- In the current study, the impacts of sulfur nutrition (atmospheric and pedospheric) on the glucosinolate content and the transcript levels and activity of myrosinase were studied in seedlings of two Brassica species, which are characterized by a high ( Brassica juncea , mustard greens) and low ( B. rapa , mustard spinach) glucosinolate content. (frontiersin.org)
- Glucosinolates (GSs) were analyzed in 56 accessions of Brassica rapa grown in the greenhouse. (wur.nl)
- Eight different glucosinolates were identified in the Brassica rapa group. (wur.nl)
- The total glucosinolate contents in Brassica rapa group varied substantially between the different accessions. (wur.nl)
- Rapid Separation of Indole Glucosinolates in Roots of Chinese Cabbage (Brassica rapa Subsp. (hindawi.com)
- S.-H. Choi, S. Park, Y. P. Lim, S.-J. Kim, J.-T. Park, and G. An, "Metabolite profiles of glucosinolates in cabbage varieties (Brassica oleracea var. (hindawi.com)
- Variation of glucosinolates in 62 varieties of Chinese cabbage (Brassica rapa L. ssp. (hindawi.com)
- Glucosinolates are the major class of secondary metabolites found in Brassica crops. (springer.com)
- The economic importance of glucosinolates in Brassica crops is due to the biological activity of their degradation products, which include isothiocyanate, nitriles and a range of indole compounds (Figs. 2 and 3). (springer.com)
- The content and composition of glucosinolates in genetically different varieties of oilseed rape (Brassica napus L. (eurekamag.com)
- Francisco M, Moreno DA, Cartea ME, Ferreres F, Garcia-Viguera C, Velasco P (2009) Simultaneous identification of glucosinolates and phenolic compounds in a representative collection of vegetables Brassica rapa . (springer.com)
- 2. We investigated the influence of heritable variation in aliphatic glucosinolates, a class of secondary metabolites produced by Brassica plants, on the relative importance of top-down and bottom-up regulation of Brevicoryne brassicae (mealy cabbage aphid) colonies in natural Brassica oleracea (wild cabbage) populations. (nerc.ac.uk)
- Selenium in soils can result in increased uptake of S and a reduction in glucosinolates in Brassica species. (tennessee.edu)
- Kinetics of Changes in Glucosinolate Concentrations during Long-Term Cooking of White Cabbage (Brassica oleracea L. ssp. (infona.pl)
- The discovery of the reduced aliphatic glucosinolate trait in the Brassica napus cultivar Bronowski (Krzymanski 1970) resulted in the development of B. napus and B. rapa cultivars with less than 30 F moles glucosinolate per gram of oil free meal. (gcirc.org)
- Leaf and root glucosinolate profiles of Chinese cabbage (Brassica rapa ssp. (bvsalud.org)
- Molecular characterization of glucosinolates and carotenoid biosynthetic genes in Chinese cabbage (Brassica rapa L. ssp. (uni-bielefeld.de)
Cruciferous vegetables13
- In a recent study , researchers set out to discover whether glucosinolates in two different cruciferous vegetables could survive the process of stir-frying, with their beneficial qualities intact. (naturalhealth365.com)
- While stir-frying left the phytochemicals intact, the researchers noted that earlier studies had shown that cooking cruciferous vegetables in water (by boiling) led to the leaching out and loss of water-soluble glucosinolates. (naturalhealth365.com)
- The team also cited an earlier study that showed that deep frying caused cruciferous vegetables to lose up to 84 percent of their glucosinolates . (naturalhealth365.com)
- A team of researchers at Wageningen University and Research wanted to determine whether glucosinolates in two different cruciferous vegetables and their beneficial properties could be preserved when they undergo the process of stir-frying. (naturalnews.com)
- Previous studies revealed that cooking cruciferous vegetables in water (boiling) resulted in the loss of glucosinolates. (naturalnews.com)
- In addition, an earlier study showed that deep frying cruciferous vegetables led to the loss of glucosinolates by up to 84 percent. (naturalnews.com)
- In conclusion, the findings of the study suggested that when cooking cruciferous vegetables, stir-frying can be preferred over boiling and deep frying so that the glucosinolate content will not be depleted. (naturalnews.com)
- Cruciferous vegetables are a rich source of glucosinolates that have established anti-carcinogenic activity. (waocp.org)
- Cruciferous vegetables are unique in that they are a rich source o f sulfur-containing compounds called glucosinolates (β-thioglucoside N-hydroxysulfates) that impart a pungent aroma and spicy . (happinessmedicine.com)
- Gluconasturtiin , also known as phenethylglucosinolate, is a widely distributed glucosinolate in cruciferous vegetables. (happinessmedicine.com)
- White varieties of cauliflower are just as rich in phytonutrients as green cruciferous vegetables, and this nutrient richness is exemplified by its glucosinolates, described below. (whfoods.org)
- This story involves unique phytonutrients in cruciferous vegetables called glucosinolates and their conversion into related phytonutrients that can take place through various kitchen preparation methods. (whfoods.org)
- In addition, researchers have identified over 150 different glucosinolates in cruciferous vegetables, and these many different glucosinolates have many different metabolic fates when a fresh cruciferous vegetable is chopped. (whfoods.org)
Abstract1
- article{506993e9-a3d0-48c9-94b7-cd9250e28aaf, abstract = {Glucosinolates are natural plant products that function in the defense toward herbivores and pathogens. (lu.se)
Intact glucosinolates7
- Analysis of intact glucosinolates by MALDI-TOF mass spectrometry. (nih.gov)
- Bennett RN, Mellon FA, Kroon PA (2004) Screening crucifer seeds as sources of specific intact glucosinolates using ion-pair high-performance liquid chromatography negative ion electrospray mass spectrometry. (springer.com)
- Isolation of Intact Glucosinolates by Column Chromatography and Determination of Their Purity. (barnesandnoble.com)
- Quantitative Analysis of Glucosinolates in Oilseed Rape Based on HPLC of Desulphoglucosinolates and HPLC of Intact Glucosinolates. (barnesandnoble.com)
- These compounds are generated by the action of the endogenous plant enzyme myrosinase, or by thioglucosidases from gut microbes following consumption of intact glucosinolates. (springer.com)
- Effects of Intact Glucosinolates and Products Produced from Glucosinolates in Myrosinase-Catalyzed Hydrolysis on the Potato Cyst Nematode ( Globodera rostochiensis Cv. (infona.pl)
- Intact glucosinolates are believed to be biologically inactive, whereas degradation products after hydrolysis have multiple roles in growth regulation and defense. (qxmd.com)
Indole13
- After MeJA treatment, the amount of indole glucosinolates increased 3- to 4-fold, and the corresponding Trp-metabolizing genes CYP79B2 and CYP79B3 were both highly induced. (plantphysiol.org)
- Specifically, the indole glucosinolate N -methoxy-indol-3-ylmethylglucosinolate accumulated 10-fold in response to MeJA treatment, whereas 4-methoxy-indol-3-ylmethylglucosinolate accumulated 1.5-fold in response to 2,6-dichloro-isonicotinic acid. (plantphysiol.org)
- The present data indicate that different indole glucosinolate methoxylating enzymes are induced by the jasmonate and the SA signal transduction pathways, whereas the aliphatic glucosinolates appear to be primarily genetically and not environmentally controlled. (plantphysiol.org)
- and third, secondary modifications of the core structure can take place, which include e.g. methoxylation of the indole structure of Trp-derived glucosinolates and oxidation of the Met-derived side chains. (plantphysiol.org)
- A defensive role for indole glucosinolates is suggested by the observation that atr1D mutant plants, which overproduce indole glucosinolates, are more resistant to M. persicae, whereas cyp79B2 cyp79B3 double mutants, which lack indole glucosinolates, succumb to M. persicae more rapidly. (ovid.com)
- Indole glucosinolate breakdown products, including conjugates formed with ascorbate, glutathione and amino acids, are elevated in the honeydew of M. persicae feeding from atr1D mutant plants, but are absent when the aphids are feeding on cyp79B2 cyp79B3 double mutants. (ovid.com)
- M. persicae feeding from wild-type plants and myrosinase-deficient tgg1 tgg2 double mutants excrete a similar profile of indole glucosinolate-derived metabolites, indicating that the breakdown is independent of these foliar myrosinases. (ovid.com)
- Therefore, the post-ingestive breakdown of indole glucosinolates provides a defense against herbivores such as aphids that can avoid glucosinolate activation by plant myrosinases. (ovid.com)
- Indole and aliphatic glucosinolates accumulated in response to K-deficiency in a manner that was respectively dependent or independent on signaling through Coronatine-Insensitive 1 (COI1). (biomedcentral.com)
- Glucosinolates, of which nearly 200 types having different substituents have been identified, are classifiable into three classes based on the structure of different amino acid precursors: aliphatic glucosinolates, indole glucosinolates, and aromatic glucosinolates. (biotecharticles.com)
- B. rapa strains with reduced indole glucosinolate content were also developed at Agriculture and Agri-Food Canada and subsequently crossed with BC86-18. (gcirc.org)
- The addition of purified indol-3-ylmethylglucosinolate to the petioles of cyp79B2 cyp79B3 mutant leaves, which do not produce indole glucosinolates, showed that this glucosinolate serves as a precursor for the aphid-induced synthesis of 4-methoxyindol-3-ylmethylglucosinolate. (qxmd.com)
- Brevicoryne brassicae performance correlated positively with concentrations of both aliphatic and indole glucosinolates in the phloem. (wur.nl)
Metabolites12
- Glucosinolates occur as secondary metabolites of almost all plants of the order Brassicales. (wikipedia.org)
- Background: Glucosinolates (GLSs) are dietary plant secondary metabolites occurring in the order Brassicales with potential health effects, in particular as anti-carcinogenic compounds. (ingentaconnect.com)
- Glucosinolates (GLs) are structurally homogenous secondary metabolites present in the Brassicaceae, Capparidaceae, Moringaceae, and Resedaceae families, as well as in other less-studied families of the order Brassicales. (springer.com)
- Glucosinolates (GS) are important plant secondary metabolites in plant resistance to herbivores, bacteria, and fungi, which have been shown to be accumulating in different organs and tissue types at varying concentrations. (frontiersin.org)
- Glucosinolates are a class of secondary metabolites with important roles in plant defense and human nutrition. (nih.gov)
- The glucosinolate content of these vegetables is broken down into metabolites when they are consumed. (naturalnews.com)
- Glucosinolates (GLS) are secondary metabolites mainly found in plants belonging to the Brassicaceae family, including also horseradish (Armoracia rusticana G. Gaertn. (bio-protocol.org)
- Glucosinolates are plant secondary metabolites composed of a thioglucose group and an amino acid side-chain. (ox.ac.uk)
- Glucosinolates, secondary metabolites found in Brassicaceae. (biotecharticles.com)
- Glucosinolates, secondary metabolites found in Brassicaceae and related families, have three moieties: a Beta- thioglucose moiety, a sulfonated oxime moiety, and a variable aglycone side chain derived from a a-amino acid. (biotecharticles.com)
- The scientists described the genetic diversity of Russian rapeseed lines and discovered new candidate genes that are potentially involved in controlling the content of glucosinolates, toxic secondary metabolites in rapeseed oil. (bioengineer.org)
- Glucosinolates are secondary metabolites of rapeseed and related cruciferous plants. (bioengineer.org)
Brassicaceae4
- One of the intriguing, although poorly described metabolic pathways in plants is the biosynthesis of glucosinolates (GSLs), a group of bioactive secondary products derived from amino acids that are found in the family Brassicaceae. (pnas.org)
- Glucosinolate profiling and antimicrobial screening of Aurinia leucadea (Brassicaceae). (mysciencework.com)
- Food plants species in the Cruciferae (Brassicaceae) family contain substances called glucosinolates, which probably play a role in the plant's defenses against predators and fungal attack. (orst.edu)
- Glucosinolates (GSs) are an important group of defensive phytochemicals mainly found in Brassicaceae . (bvsalud.org)
Glucoraphanin2
- Most glucosinolates are actually derived from chain-elongated homologues of these amino acids, e.g. glucoraphanin is derived from dihomomethionine, which is methionine chain-elongated twice). (wikipedia.org)
- In a cohort of 2,121 German participants in the European Prospective Investigation into Cancer and Nutrition (EPIC study), glucobrassicin, sinigrin, glucoraphasatin (dehydroerucin), glucoraphanin, and glucoiberin were found to contribute most to total glucosinolate intake ( Source ). (happinessmedicine.com)
Metabolism4
- Analysis of steady-state messenger RNA levels of glucosinolate pathway genes indicates that IQD1 affects expression of multiple genes with roles in glucosinolate metabolism. (nih.gov)
- After thioglycosidic bond has been cleaved from glucosinolate, how does metabolism proceed? (brainscape.com)
- Here, we investigated the changes in protein structure that have occurred during the recruitment of IPMS from amino acid to glucosinolate metabolism. (nih.gov)
- A number of mechanisms are believed to be involved in the glucosinolate-induced suppression of carcinogenesis, including the induction of apoptosis, biotransformation of xenobiotic metabolism, oxidative stress, alteration of caspase activity, angiogenesis, histone deacytylation and cell cycle arrest. (waocp.org)
Different glucosinolates3
- different glucosinolates have different side groups, and it is variation in the side group that is responsible for the variation in the biological activities of these plant compounds. (wikipedia.org)
- About 132 different glucosinolates are known to occur naturally in plants. (wikipedia.org)
- Rapeseed-Determination of the content of the different glucosinolates in rapeseeds (colza) using high-performance liquid chromatography. (hindawi.com)
Individual glucosinolates4
- The methodology was used to characterize a number of individual glucosinolates either produced by synthetic chemistry or isolated from plants. (nih.gov)
- Analysis of Individual Glucosinolates in Rapeseeds. (barnesandnoble.com)
- Composition and ratios of individual glucosinolates in leaves were different than those of seeds. (eurekamag.com)
- However, very little is known about the importance of individual glucosinolates in plant defense and the regulation of their production in response to herbivory. (qxmd.com)
Vegetables5
- Determination of Glucosinolates in Crucifer Vegetables for Human Consumption and Rapeseed. (barnesandnoble.com)
- They found that stir-frying the vegetables, even at the highest temperatures and longest durations, did not deplete them of their glucosinolates - including glucobrassicanapin, the most abundant form. (naturalhealth365.com)
- Results revealed that stir-frying the vegetables did not remove the glucosinolates content. (naturalnews.com)
- However, certain vegetables, sprouts and seeds may contain a predominant amount of one glucosinolate. (happinessmedicine.com)
- Cook vegetables that are high in glucosinolates by steaming them. (cookinglight.com)
Isothiocyanate5
- Additionally, we showed that 4-α-L-rhamnopyranosyloxy)benzyl isothiocyanate (4RBITC), the isothiocyanate created by hydrolysis of "glucomoringin" (4RBGS or 4-(α-L-rhamnopyranosyloxy)benzyl glucosinolate) from M . oleifera is a potent and selective antibiotic against H . pylori 15 . (nature.com)
- The essence of glucosinolate chemistry is their ability to convert into an isothiocyanate (a "mustard oil") upon hydrolysis of the thioglucoside bond by the enzyme myrosinase. (wikipedia.org)
- The isothiocyanate hydrolase promotes fungal growth in the presence of the toxins, and contributes to the virulence of S. sclerotiorum on glucosinolate-producing plants. (nature.com)
- Taste detection of the non-volatile isothiocyanate moringin results in deterrence to glucosinolate-adapted insect larvae. (uni-bielefeld.de)
- When glucosinolates are metabolized by an enzyme called myrosinase, they produce a bioactive isothiocyanate compound. (theepochtimes.com)
Sulfur compounds2
- The glucosinolate content was not affected by H 2 S and SO 2 exposure, demonstrating that these sulfur compounds did not form a sink for excessive atmospheric supplied sulfur. (frontiersin.org)
- The significance of myrosinase in the in situ turnover in these secondary sulfur compounds needs to be questioned, since there was no direct co-regulation between the content of glucosinolates and the transcript level and activity of myrosinase. (frontiersin.org)
Myrosinases2
- These plants also constitutively synthesize and store glucosinolates, which are converted by endogenous S -glycosyl hydrolases (myrosinases) into compounds that function as insect feeding and/or oviposition stimulants or deterrents ( 7 ). (sciencemag.org)
- Rapid incorporation of glucosinolates as a strategy used by a herbivore to prevent activation by myrosinases", Insect Biochemistry and Molecular Biology , vol. 52, 2014, pp. 115-123. (uni-bielefeld.de)
Sinigrin3
- 3. Aphid colony sizes were significantly smaller on plants producing sinigrin, compared with plants producing alternative aliphatic glucosinolates. (nerc.ac.uk)
- Sinigrin is one of cabbage's sulfur-containing glucosinolates that has received special attention in cancer prevention research. (whfoods.com)
- Certain glucosinolates such as sinigrin and progoitrin, and their respective breakdown products are often bitter or astringent. (biotecharticles.com)
Plant22
- The pungency of those plants is due to mustard oils produced from glucosinolates when the plant material is chewed, cut, or otherwise damaged. (wikipedia.org)
- Glucosinolates are naturally occurring plant compounds that may be important in the dietary prevention of cancer. (nih.gov)
- The method was used for crude plant extracts to rapidly examine the glucosinolate profile of the plant. (nih.gov)
- In this chapter, some of the most recent information on glucosinolate-containing plant families is presented. (springer.com)
- Thorough chewing of fresh sprouts exposes the glucosinolates to plant myrosinase and significantly increases dithiocarbamate excretion. (aacrjournals.org)
- Nevertheless, some cosmopolitan fungal pathogens, such as the necrotrophic white mold Sclerotinia sclerotiorum , are able to infect many plant hosts including glucosinolate producers. (nature.com)
- S. F. Vaughn, "Glucosinolates as natural pesticides," in Principles Practices in Plant Allelochemical Interactions , S. J. Cutler and H. G. Cutler, Eds. (hindawi.com)
- Initial in vitro evaluations of the antibacterial activities of glucosinolate enzymatic hydrolysis products against plant pathogenic bacteria," Journal of Applied Microbiology , vol. 106, no. 6, pp. 2096-2105, 2009. (hindawi.com)
- Glucosinolates are natural plant products that function in the defense toward herbivores and pathogens. (plantphysiol.org)
- Glucosinolates are amino acid-derived natural plant products that function in the defense against herbivores and microorganisms. (plantphysiol.org)
- In addition, Se's presence within the plant seems to have a negative impact on the production of certain glucosinolates despite adequate availability of S. (tennessee.edu)
- Myrosinase (see ref. 18 ) is normally segregated from glucosinolates and is released when plant cells are injured. (pnas.org)
- For these reasons, we suggest that polymorphism for aliphatic glucosinolates in natural populations offers an attractive system for the study of ecological genetics of plant-herbivore interactions. (ox.ac.uk)
- However, the unique glucosinolate (glucomoringin) found in the moringa plant is metabolized to moringin . (theepochtimes.com)
- In addition to glucomoringin and 4GBGS, moringa oleifera also contains at least 10 other glucosinolates that work together to provide many of the health benefits of the plant. (theepochtimes.com)
- Glucosinolates are sulfur-containing compounds present in many plant families but most often associated with the Cruciferae. (gcirc.org)
- Aliphatic glucosinolate is an important secondary metabolite responsible in plant defense mechanism and carcinogenic activity. (elsevier.com)
- This altered glucosinolate profile is not a systemic plant response, but is limited to the area in which aphids are feeding. (qxmd.com)
- Glucosinolates from Host Plants Influence Growth of the Parasitic Plant Cuscuta gronovii and Its Susceptibility to Aphid Feeding. (qxmd.com)
- The cabbage aphid Brevicoryne brassicae is a specialist herbivore that sequesters glucosinolates from its host plant as a defense against its predators. (wur.nl)
- The study shows that there are differential herbivore-mediated effects of glucosinolates on a predator and a parasitoid of a specialist aphid that selectively sequesters glucosinolates from its host plant. (wur.nl)
- Most of the work in his department focuses on two major groups of plant defenses: glucosinolates and terpenoids. (wikipedia.org)
Aromatic glucosinolates1
- Aromatic glucosinolates include indolic glucosinolates, such as glucobrassicin, derived from tryptophan and others from phenylalanine, its chain-elongated homologue homophenylalanine, and sinalbin derived from tyrosine. (wikipedia.org)
Defense4
- Thus, different defense pathways activate subsets of biosynthetic enzymes, leading to the accumulation of specific glucosinolates. (plantphysiol.org)
- The cleavage of glucosinolates by myrosinase to produce toxic breakdown products is a characteristic insect defense of cruciferous plants. (ovid.com)
- Based on our results we propose that under K-deficiency plants produce oxylipins and glucosinolates to enhance their defense potential against herbivorous insects and create reversible storage for excess S and N. (biomedcentral.com)
- Accumulating evidence increasingly supports the beneficial effects of dietary glucosinolates on overall health, including as potential anti-cancer agents, because of their role in the prevention of the initiation of carcinogenesis via the induction of cellular defense detoxifying/antioxidant enzymes and their epigenetic mechanisms, including modification of the CpG methylation of cancer-related genes, histone modification regulation and changes in the expression of miRNAs. (altmetric.com)
Cabbage5
- Glucosinolates are natural components of many pungent plants such as mustard, cabbage, and horseradish. (wikipedia.org)
- The researchers also found that glucobrassicanapin is the most abundant form of glucosinolate in fresh Chinese cabbage and bok choy. (naturalnews.com)
- 4. Our results provide evidence for glucosinolate-mediated, bottom-up regulation of mealy cabbage aphid colonies in natural populations, but we found no indication of top-down regulation. (nerc.ac.uk)
- And a submitted companion paper reports dietary glucosinolate from Brussels sprouts and cabbage drove coronary heart diseases. (foundmyfitness.com)
- It's also worth noting here that a second glucosinolate found in cabbage-glucobrassicin-can be converted into two cancer-protective compounds. (whfoods.com)
Allylglucosinolate versus allyl glucosinolate2
- The spelling of a glucosinolate name as one word or two (e.g. allylglucosinolate versus allyl glucosinolate) has the same meaning, and both spellings are in use. (wikipedia.org)
- Spelling glucosinolate names in one or two words (e.g. allylglucosinolate versus allyl glucosinolate) are both in use and has equivalent meaning. (wikipedia.org)
Total glucosinolate contents1
- Quick Reflectometric Determination of Total Glucosinolate Contents in Trade Samples. (barnesandnoble.com)
Plants21
- The glucosinolates are also found in seeds of these plants. (wikipedia.org)
- The plants contain the enzyme myrosinase, which, in the presence of water, cleaves off the glucose group from a glucosinolate. (wikipedia.org)
- Songsak T, Lockwood GB (2002) Glucosinolates of seven medicinal plants from Thailand. (springer.com)
- The glucosinolate content was decreased in sulfate-deprived plants, though its proportion of organic sulfur fraction was higher than that of sulfate-sufficient plants, both in absence and presence of H 2 S and SO 2 . (frontiersin.org)
- The aim of the study was to gain insight into the significance of glucosinolates in sulfur storage and the role of myrosinase in the re-distribution of sulfur in sulfate-deprived plants. (frontiersin.org)
- Bak S, Nielsen HL, Halkier BA (1998) The presence of CYP79 homologues in glucosinolateproducing plants shows evolutionary conservation of the enzymes in the conversion of amino acid to aldoxime in the biosynthesis of cyanogenic glycosides and glucosinolates. (springer.com)
- We manipulated natural enemy pressure on plants differing in their glucosinolate profiles, and monitored aphid colony growth and disperser production. (nerc.ac.uk)
- Transcript and glucosinolate profiles of K-deficient plants resembled those of herbivore attacked plants. (biomedcentral.com)
- In spite of higher S concentrations, there was a decrease in production of 5 of the 7 glucosinolates analyzed in Se enriched plants. (tennessee.edu)
- Plants in elevated S treatments had higher glucosinolate production than Se treated plants. (tennessee.edu)
- The aim of our study was to investigate fungistatic properties of glucosinolates from seeds of four cruciferous plants against Candida albicans , obtained from different sections of the gastrointestinal and respiratory tracts. (pjoes.com)
- Other health benefits from moringa plants are the unique glucosinolates that are unique to the tree. (theepochtimes.com)
- Low glucosinolate plants with good yellow seed colour were selected from Tobin and evaluated in progeny rows in 1985. (gcirc.org)
- Fifty single plants were selected for low glucosinolate content using the rapid glucose test strip method. (gcirc.org)
- Twenty-five individuals were selected from these plants for low glucosinolate content and bulked for a field increase in 1985. (gcirc.org)
- Thirty low glucosinolate plants from the field increase were selected, and twenty progeny of each were bud-selfed and inter-pollinated in the greenhouse. (gcirc.org)
- Finally, seven very low glucosinolate plants were selected and crossed in a half-diallel, inter-pollinated and bud-selfed. (gcirc.org)
- Cruciferous plants produce a wide variety of glucosinolates as a protection against herbivores and pathogens. (qxmd.com)
- Once verified on an independent set of plants, the markers can be readily used for breeding new varieties and hybrids with low glucosinolate content. (bioengineer.org)
- Analysis of glucosinolate hydrolysis profiles of transgenic A. thaliana plants overexpressing AtNSP2 confirms its nitrile-specifier activity in planta. (qxmd.com)
- Comparative biochemical characterization of nitrile-forming proteins from plants and insects that alter myrosinase-catalysed hydrolysis of glucosinolates. (qxmd.com)
Genes9
- A working model for regulation of GSL production involving these genes, renamed Production of Methionine-Derived Glucosinolate ( PMG ) 1 and 2 , are postulated. (pnas.org)
- Two genes, PEN2 and PEN3 , are also necessary for resistance to pathogens and are required for both callose deposition and glucosinolate activation, suggesting that the pathogen-triggered callose response is required for resistance to microbial pathogens. (sciencemag.org)
- GUS expression reveals IQD1 promoter activity mainly in vascular tissues of all organs, consistent with the expression patterns of several glucosinolate-related genes. (nih.gov)
- In parallel, expression of glucosinolate biosynthetic genes of the CYP79 gene family and the UDPG:thiohydroximate glucosyltransferase was monitored. (plantphysiol.org)
- FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes," NEW PHYTOLOGIST , vol. 227, no. 4, pp. 1124-1137, 2020. (ugent.be)
- Known genes for aliphatic glucosinolates were retrieved from KEGG and AraCyc databases. (elsevier.com)
- This study showed that a total of 506 genes were co-expressed with the 61 aliphatic glucosinolate biosynthesis genes. (elsevier.com)
- Meanwhile, three other genes with high potential to be involved in the aliphatic glucosinolates biosynthetic pathway were identified, i.e., methylthioalkylmalate-like synthase 4 (MAML-4) and aspartate aminotransferase (ASP1 and ASP4). (elsevier.com)
- This helped identify both the genetic markers of glucosinolate content in oil and the linked candidate genes potentially involved in regulating the biosynthesis of glucosinolates. (bioengineer.org)
Concentrations3
- Gluconasturtiin was found in relatively high concentrations in komastsuna (14.6 µmol/100 g FW), yellow sarson (7.1 µmol/ 100 g FW) and constitutes as much as 24% of the total amount of glucosinolates. (wur.nl)
- We correlated this with phloem and aphid glucosinolate concentrations and emission of volatiles. (wur.nl)
- Glucosinolate concentration in B. brassicae correlated negatively with performance of the predator, but positively with performance of the parasitoid, possibly because the aphids with the highest glucosinolate concentrations had a higher body weight. (wur.nl)
Herbivores1
- In controlled conditions in the laboratory or in field trials, many aliphatic glucosinolates, or their degradation products, affect the behaviour of herbivores. (ox.ac.uk)
Enzyme3
- Du LC, Lykkesfeldt J, Olsen CE, Halkier BA (1995) Involvement of cytochrome P450 in oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomal enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba . (springer.com)
- Physical tissue or cell injury leads to the breakdown of glucosinolates through the hydrolytic action of the enzyme myrosinase, resulting in the production of compounds including isothiocynates, thiocyanates and nitriles. (biotecharticles.com)
- We also detected a significant increase in the activity of myrosinase, the enzyme catalyzing the initial step in glucosinolate breakdown, coinciding with a strong induction of the main leaf myrosinase isoforms TGG1 and TGG2. (mpg.de)
Wide variety of glucosinolates1
- A wide variety of glucosinolates exists owing to modification of the side-chain structure. (ox.ac.uk)
Influencing glucosinolate levels1
- The importance of genotype as a factor influencing glucosinolate levels is also considered based on results of studies that have examined this. (novapublishers.com)
Accumulation1
- As IQD1 is induced by mechanical stimuli, we propose IQD1 to be novel nuclear factor that integrates intracellular Ca(2+) signals to fine-tune glucosinolate accumulation in response to biotic challenge. (nih.gov)
Enzymes3
- Glucosinolates are the enzymes that help with cellular detoxification and the elimination of damaging free radicals. (naturalnews.com)
- Bak S, Feyereisen R (2001) The involvement of two P450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis. (springer.com)
- Following tissue damage, myrosinase enzymes catalyse the decomposition of glucosinolates to a variety of volatile and nonvolatile products. (ox.ac.uk)
Dietary1
- In animal studies, glucosinolates and their breakdown products have inhibited tumor formation, although this anti-carcinogenic effect depends on the study design, the type of cancer being studied, whether other dietary components are present, and the timing of the administration of the glucosinolate compound. (orst.edu)
Biosynthetic2
- Five transcription factors have been predicted to be involved in the biosynthetic pathway of aliphatic glucosinolate, namely SEPALLATA 3 (SEP3), PHYTOCHROME INTERACTING FACTOR 3-like 5 (AtbHLH15/PIL5), ELONGATED HYPOCOTYL 5 (HY5), AGAMOUS-like 15 (AGL15) and GLABRA 3 (GL3). (elsevier.com)
- These findings can be used to complete the aliphatic glucosinolate biosynthetic pathway in A. thaliana and to update the information on the glucosinolate-related pathways in public metabolic databases. (elsevier.com)
Substance that breaks do2
- The team reported that stir-frying inactivated myrosinase (a substance that breaks down glucosinolates) thereby helping to prevent their release and loss. (naturalhealth365.com)
- The research team explained that such retention occurred because stir-frying inactivated myrosinase, which is a substance that breaks down glucosinolates. (naturalnews.com)
Naturally occurring glu1
- In this review, we summarize the cancer chemopreventive role of naturally occurring glucosinolate derivatives as inhibitors of carcinogenesis, with particular emphasis on specific molecular targets and epigenetic alterations in in vitro and in vivo human cancer animal models. (altmetric.com)
Conversion of glucosinolates1
- Finally, when bowel microflora were reduced by mechanical cleansing and antibiotics, the conversion of glucosinolates became negligible. (aacrjournals.org)
Properties of glucosinolates1
- Does stir frying destroy the cancer-fighting properties of glucosinolates? (naturalhealth365.com)
Degradation of glucosinolates1
- Internal degradation of glucosinolates might also be involved in diurnal or developmental adaptations of the glucosinolate profile. (mpg.de)
Composition of glucosinolates2
- The findings were supported by the composition of glucosinolates in the coronatine-insensitive mutant coi1 , the ctr1 mutant displaying constitutive triple response, and the SA-overproducing mpk4 and cpr1 mutants. (plantphysiol.org)
- Content and composition of glucosinolates in leaves of 2 traditional and 8 low-glucosinolate (LG) varieties of oilseed rape (B. napus) grown in Poznan during 1994-95 was determined by HPLC at 3 different stages of development. (eurekamag.com)
Amino acids3
- They are synthesized from certain amino acids: So-called aliphatic glucosinolates derived from mainly methionine, but also alanine, leucine, isoleucine, or valine. (wikipedia.org)
- Glucosinolates are derived from amino acids and have a core structure consisting of a β-D-glucopyranose residue linked to a ( Z )- N -hydroximino sulfate ester via a sulfur atom and a variable side chain ( Halkier and Gershenzon, 2006 ). (frontiersin.org)
- The first committed step in biosynthesis of the core structure of glucosinolates is the conversion of amino acids to the corresponding aldoximes. (plantphysiol.org)
Glucobrassicin1
- They are the aliphatic glucosinolates progoitrin (PRO), gluconapin (NAP), glucobrassicanapin (GBN), the indolyl glucosinolates 4-hydroxyglucobrassicin (4OH), glucobrassicin (GBC), 4-methoxyglucobrassicin (4ME), neoglucobrassicin (NEO) and the aromatic glucosinolate gluconasturtiin (NAS). (wur.nl)
Progoitrin1
- This is largely due to 5-vinyloxazolidine2-thione (Fig. 2), derived from 2-hydroxy-3-butenyl glucosinolate ("progoitrin"), which, as the name suggests, has goitrogenic activity. (springer.com)
Indolyl2
- Purification and Analysis of Desulfo Indolyl Glucosinolates. (barnesandnoble.com)
- These compounds, along with indolyl glucosinolate degradation products, have also been shown to have anticarcinogenic activity. (springer.com)
Crucifers1
- 1-Isothiocyanato-3-(methylsulfinyl)-propane (IMSP) is a glucosinolate hydrolysis product formed from 3-methylsulfinylpropylglucosinolate when crucifers are eaten. (illinois.edu)
High-performance li1
- European Commission (EC), "Oil seeds-determination of glucosinolates High Performance Liquid Chromatography," Official Journal of the European Communities , pp. 03-07, 1990, L 170/28. (hindawi.com)