Glucose
Glucose Tolerance Test
Glucose Intolerance
A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
Glucose Oxidase
An enzyme of the oxidoreductase class that catalyzes the conversion of beta-D-glucose and oxygen to D-glucono-1,5-lactone and peroxide. It is a flavoprotein, highly specific for beta-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide produced in the reaction. (From Enzyme Nomenclature, 1992) EC 1.1.3.4.
Glucose Transporter Type 1
Glucose Transporter Type 4
A glucose transport protein found in mature MUSCLE CELLS and ADIPOCYTES. It promotes transport of glucose from the BLOOD into target TISSUES. The inactive form of the protein is localized in CYTOPLASMIC VESICLES. In response to INSULIN, it is translocated to the PLASMA MEMBRANE where it facilitates glucose uptake.
Monosaccharide Transport Proteins
Blood Glucose Self-Monitoring
Glucose 1-Dehydrogenase
Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Glucose Transporter Type 2
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Glucagon
A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
Glucose Dehydrogenases
Glycolysis
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
Gluconeogenesis
Islets of Langerhans
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
Hypoglycemia
Lactic Acid
Hexokinase
An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. (From Enzyme Nomenclature, 1992) EC 2.7.1.1.
Glucose-6-Phosphate
Glucokinase
Fructose
Biological Transport
Glucose Metabolism Disorders
3-O-Methylglucose
Fatty Acids, Nonesterified
Diabetes Mellitus
Liver
Sodium-Glucose Transporter 1
Diabetes Mellitus, Experimental
Muscle, Skeletal
Homeostasis
Energy Metabolism
Glycerol
C-Peptide
The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
Insulin-Secreting Cells
Adipose Tissue
Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.
Carbohydrate Metabolism
Dietary Carbohydrates
Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)
Glucose Solution, Hypertonic
Hemoglobin A, Glycosylated
Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.
Hyperinsulinism
A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
Glycosuria
Obesity
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Glucose-6-Phosphatase
Carbon Isotopes
Uridine Diphosphate Glucose
A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Glucagon-Like Peptide 1
A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
Body Weight
Prediabetic State
Rats, Wistar
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Oxidation-Reduction
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Cells, Cultured
Rats, Sprague-Dawley
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Lipids
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Carbon Radioisotopes
Rats, Inbred Strains
Lipid Metabolism
3-Hydroxybutyric Acid
Galactose
An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
Muscle Proteins
Oxygen Consumption
Pyruvic Acid
Adipocytes
Reference Values
Glycogenolysis
The release of GLUCOSE from GLYCOGEN by GLYCOGEN PHOSPHORYLASE (phosphorolysis). The released glucose-1-phosphate is then converted to GLUCOSE-6-PHOSPHATE by PHOSPHOGLUCOMUTASE before entering GLYCOLYSIS. Glycogenolysis is stimulated by GLUCAGON or EPINEPHRINE via the activation of PHOSPHORYLASE KINASE.
Fermentation
Fatty Acids
Dose-Response Relationship, Drug
Biosensing Techniques
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Starch
Glycogen Synthase
Acetates
Pentose Phosphate Pathway
An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.
Adenosine Triphosphate
Biological Transport, Active
Gastric Inhibitory Polypeptide
Models, Biological
Sodium-Glucose Transport Proteins
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Maltose
Insulin Infusion Systems
Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor.
Epinephrine
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Sucrose
Sorbitol
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. It is also used in many manufacturing processes, as a pharmaceutical aid, and in several research applications.
Citric Acid Cycle
Dietary Fats
Diabetes, Gestational
Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
Infusions, Intravenous
Amino Acids
AMP-Activated Protein Kinases
Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.
Phosphorylation
Streptozocin
Rats, Zucker
Carbon Dioxide
Hydrogen-Ion Concentration
Glutamine
Glucose Transporter Type 5
Mannitol
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Body Mass Index
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
Fluorodeoxyglucose F18
The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)
Ketone Bodies
Sweetening Agents
Proinsulin
A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC BETA CELLS, is comprised sequentially of the N-terminal B-chain, the proteolytically removable connecting C-peptide, and the C-terminal A-chain. It also contains three disulfide bonds, two between A-chain and B-chain. After cleavage at two locations, insulin and C-peptide are the secreted products. Intact proinsulin with low bioactivity also is secreted in small amounts.
Monitoring, Ambulatory
Osmolar Concentration
Sodium-Glucose Transporter 2
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Mice, Obese
Leptin
Somatostatin
A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Metformin
A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
Pregnancy
Pyruvate Kinase
Infusions, Parenteral
Gene Expression Regulation
Tolbutamide
Magnetic Resonance Spectroscopy
Cross-Over Studies
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Dialysis Solutions
Alanine
Receptor, Insulin
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.
Pancreas
A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
Saccharomyces cerevisiae
Carbon
Risk Factors
Metabolic Syndrome X
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
Hormones
Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
Glucose-6-Phosphate Isomerase
An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.
Dogs
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Carbohydrates
Lactose
Fructosamine
Glycemic Index
Body Composition
Monosaccharides
Area Under Curve
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
Aminoimidazole Carboxamide
Glucans
Insulin Receptor Substrate Proteins
A structurally-related group of signaling proteins that are phosphorylated by the INSULIN RECEPTOR PROTEIN-TYROSINE KINASE. The proteins share in common an N-terminal PHOSPHOLIPID-binding domain, a phosphotyrosine-binding domain that interacts with the phosphorylated INSULIN RECEPTOR, and a C-terminal TYROSINE-rich domain. Upon tyrosine phosphorylation insulin receptor substrate proteins interact with specific SH2 DOMAIN-containing proteins that are involved in insulin receptor signaling.
3T3-L1 Cells
Mutation
Cell Membrane
Radioisotope Dilution Technique
Adiponectin
A 30-kDa COMPLEMENT C1Q-related protein, the most abundant gene product secreted by FAT CELLS of the white ADIPOSE TISSUE. Adiponectin modulates several physiological processes, such as metabolism of GLUCOSE and FATTY ACIDS, and immune responses. Decreased plasma adiponectin levels are associated with INSULIN RESISTANCE; TYPE 2 DIABETES MELLITUS; OBESITY; and ATHEROSCLEROSIS.
Jejunum
Blotting, Western
Phosphoenolpyruvate Carboxykinase (GTP)
alpha-Glucosidases
Mannose
Monitoring, Physiologic
Denitrifying Pseudomonas aeruginosa: some parameters of growth and active transport. (1/28082)
Optimal cell yield of Pseudomonas aeruginosa grown under denitrifying conditions was obtained with 100 mM nitrate as the terminal electron acceptor, irrespective of the medium used. Nitrite as the terminal electron acceptor supported poor denitrifying growth when concentrations of less than 15 mM, but not higher, were used, apparently owing to toxicity exerted by nitrite. Nitrite accumulated in the medium during early exponential phase when nitrate was the terminal electron acceptor and then decreased to extinction before midexponential phase. The maximal rate of glucose and gluconate transport was supported by 1 mM nitrate or nitrite as the terminal electron acceptor under anaerobic conditions. The transport rate was greater with nitrate than with nitrite as the terminal electron acceptor, but the greatest transport rate was observed under aerobic conditions with oxygen as the terminal electron acceptor. When P. aeruginosa was inoculated into a denitrifying environment, nitrate reductase was detected after 3 h of incubation, nitrite reductase was detected after another 4 h of incubation, and maximal nitrate and nitrite reductase activities peaked together during midexponential phase. The latter coincided with maximal glucose transport activity. (+info)Fecal coliform elevated-temperature test: a physiological basis. (2/28082)
The physiological basis of the Eijkman elevated-temperature test for differentiating fecal from nonfecal coliforms was investigated. Manometric studies indicated that the inhibitory effect upon growth and metabolism in a nonfecal coliform at 44.5 degrees C involved cellular components common to both aerobic and fermentative metabolism of lactose. Radioactive substrate incorporation experiments implicated cell membrane function as a principal focus for temperature sensitivity at 44.5 degrees C. A temperature increase from 35 to 44.5 degrees C drastically reduced the rates of [14C]glucose uptake in nonfecal coliforms, whereas those of fecal coliforms were essentially unchanged. In addition, relatively low levels of nonfecal coliform beta-galactosidase activity coupled with thermal inactivation of this enzyme at a comparatively low temperature may also inhibit growth and metabolism of nonfecal coliforms at the elevated temperature. (+info)Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus. (3/28082)
Previously we demonstrated the expression of the long form of the leptin receptor in rodent pancreatic beta-cells and an inhibition of insulin secretion by leptin via activation of ATP-sensitive potassium channels. Here we examine pancreatic islets isolated from pancreata of human donors for their responses to leptin. The presence of leptin receptors on islet beta-cells was demonstrated by double fluorescence confocal microscopy after binding of a fluorescent derivative of human leptin (Cy3-leptin). Leptin (6.25 nM) suppressed insulin secretion of normal islets by 20% at 5.6 mM glucose. Intracellular calcium responses to 16.7 mM glucose were rapidly reduced by leptin. Proinsulin messenger ribonucleic acid expression in islets was inhibited by leptin at 11.1 mM, but not at 5.6 mM glucose. Leptin also reduced proinsulin messenger ribonucleic acid levels that were increased in islets by treatment with 10 nM glucagon-like peptide-1 in the presence of either 5.6 or 11.1 mM glucose. These findings demonstrate direct suppressive effects of leptin on insulin-producing beta-cells in human islets at the levels of both stimulus-secretion coupling and gene expression. The findings also further indicate the existence of an adipoinsular axis in humans in which insulin stimulates leptin production in adipocytes and leptin inhibits the production of insulin in beta-cells. We suggest that dysregulation of the adipoinsular axis in obese individuals due to defective leptin reception by beta-cells may result in chronic hyperinsulinemia and may contribute to the pathogenesis of adipogenic diabetes. (+info)Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. (4/28082)
Expression of genes encoding starch-degrading enzymes is regulated by glucose repression in the yeast Saccharomyces cerevisiae. We have identified a transcriptional repressor, Nrg1, in a genetic screen designed to reveal negative factors involved in the expression of STA1, which encodes a glucoamylase. The NRG1 gene encodes a 25-kDa C2H2 zinc finger protein which specifically binds to two regions in the upstream activation sequence of the STA1 gene, as judged by gel retardation and DNase I footprinting analyses. Disruption of the NRG1 gene causes a fivefold increase in the level of the STA1 transcript in the presence of glucose. The expression of NRG1 itself is inhibited in the absence of glucose. DNA-bound LexA-Nrg1 represses transcription of a target gene 10.7-fold in a glucose-dependent manner, and this repression is abolished in both ssn6 and tup1 mutants. Two-hybrid and glutathione S-transferase pull-down experiments show an interaction of Nrg1 with Ssn6 both in vivo and in vitro. These findings indicate that Nrg1 acts as a DNA-binding repressor and mediates glucose repression of the STA1 gene expression by recruiting the Ssn6-Tup1 complex. (+info)Ischemic tolerance in murine cortical cell culture: critical role for NMDA receptors. (5/28082)
Murine cortical cultures containing both neurons and glia (days in vitro 13-15) were exposed to periods of oxygen-glucose deprivation (5-30 min) too brief to induce neuronal death. Cultures "preconditioned" by sublethal oxygen-glucose deprivation exhibited 30-50% less neuronal death than controls when exposed to a 45-55 min period of oxygen-glucose deprivation 24 hr later. This preconditioning-induced neuroprotection was specific in that neuronal death induced by exposure to excitotoxins or to staurosporine was not attenuated. Neuroprotection was lost if the time between the preconditioning and severe insult were decreased to 7 hr or increased to 72 hr and was blocked if the NMDA antagonist 100 microM 3-((D)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid was applied during the preconditioning insult. This was true even if the duration of preconditioning was increased as far as possible (while still remaining sublethal). A similar preconditioning effect was also produced by sublethal exposure to high K+, glutamate, or NMDA but not to kainate or trans-1-aminocyclopentane-1, 3-dicarboxylic acid. (+info)Enhanced myocardial glucose use in patients with a deficiency in long-chain fatty acid transport (CD36 deficiency). (6/28082)
CD36 is a multifunctional, 88 kDa glycoprotein that is expressed on platelets and monocytes/macrophages. CD36 also has high homology with the long-chain fatty acid (LFA) transporter in the myocardium. Although platelet and monocyte CD36 levels can indicate a CD36 deficiency, they cannot predict specific clinical manifestations in the myocardium of a given person. We examined the hypothesis that a deficiency in LFA transport augments myocardial glucose uptake in patients with a type I CD36 deficiency. METHODS: Seven fasting patients with a type I CD36 deficiency and 9 controls were assessed by cardiac radionuclide imaging using beta-methyl-p-iodophenyl-pentadecanoic acid (BMIPP) as a LFA tracer and by PET with 18F-fluorodeoxyglucose (FDG). RESULTS: None of the patients with a CD36 deficiency showed myocardial uptake of BMIPP. The percentage dose uptake of BMIPP in these subjects was significantly lower than that in normal controls (1.31+/-0.24 versus 2.90+/-0.2; P < 0.005). PET studies revealed that myocardial FDG accumulation was substantially increased in patients with a CD36 deficiency. Quantitative analysis showed that the percentage dose uptake of FDG in patients with a CD36 deficiency was significantly higher than that in normal controls (1.28+/-0.35 versus 0.43+/-0.22; P< 0.01). CONCLUSION: CD36 functions as a major myocardial LFA transporter and its absence may cause a compensatory upregulation of myocardial glucose uptake. (+info)Effect of tumor necrosis factor alpha on vascular resistance, nitric oxide production, and glucose and oxygen consumption in perfused tissue-isolated human melanoma xenografts. (7/28082)
The effect of tumor necrosis factor alpha (TNF-alpha) on vascular resistance, nitric oxide production, and consumption of oxygen and glucose was examined in a perfused tissue-isolated tumor model in nude mice. One experimental group was perfused with heparinized Krebs-Henseleit buffer, a second one was perfused with TNF-alpha (500 microgram/kg) 5 h before perfusion. The vascular resistance increased significantly 5 h after TNF-alpha injection. The increase in vascular resistance did not seem to be mediated by a decrease in tumor nitric oxide production, as determined by perfusate nitrate/nitrite concentrations, but may be due to aggregation of leukocytes, platelets, and erythrocytes and/or endothelial consumption among the three experimental groups. The oxygen consumption was linearly dependent on the amount of available oxygen in the perfusate, whereas the glucose consumption was constant and independent of the glucose delivery rate. The present experiments provide new insights into physiological and metabolic mechanisms of action of TNF- alpha for optimization of future treatment schedules involving TNF-alpha. (+info)A possible role for the pentose phosphate pathway of spermatozoa in gamete fusion in the mouse. (8/28082)
Glucose metabolism is essential for successful gamete fusion in the mouse. Although the metabolic activity of the oocyte does not appear to play a significant role in the fusion step, the metabolic role of the spermatozoon is not known. The aim of this study was therefore to characterize the role of glucose metabolism in mouse spermatozoa. Initially, the high-affinity glucose transporter GLUT3 was identified in mouse sperm. In characterizing the glucose metabolism of mouse sperm, we have shown 1) that mouse epididymal spermatozoa have a functional pentose phosphate pathway (PPP), implying that they produce NADPH, which is required for reducing reactions, and ribose 5-phosphate, which is required for nucleic acid synthesis; and 2) that sperm are able to fuse with the oocyte when NADPH is substituted for glucose, suggesting that sperm need to produce NADPH via the PPP in order to be able to achieve fertilization. The existence of an NADPH-regulated event that influences the ability of the sperm to fuse with the oocyte is envisaged. (+info)
Glucose uptake and metabolism by RBCs from fish with different extracellular glucose levels | Journal of Experimental Biology
Triphasic changes of cytoplasmic CA2+ associated with early glucose effects on beta-cell membrane potential. :: MPG.PuRe
Effect of hyperglycaemia on glucose concentration of human nasal secretions | Clinical Science
Repositorio da Producao Cientifica e Intelectual da Unicamp: Diurnal variations in insulin secretion and K+ permeability in...
High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase...
PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. - Radcliffe Department of Medicine
Two different repressors collaborate to restrict expression of the yeast glucose transporter genes HXT2 and HXT4 to low levels...
Effect of glucose treatment on basal and FSH- or IGF-1- | Open-i
High glucose level in blood
Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability |...
High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice<...
Aberrant Intracellular pH Regulation Limiting Glyceraldehyde-3-Phosphate Dehydrogenase Activity in the Glucose-Sensitive Yeast...
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Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
Features of Regional Cerebral Glucose Metabolism Abnormality in Corticobasal Degeneration - Abstract - Dementia and Geriatric...
Ca2+-dependent demethylation of phosphatase PP2Ac promotes glucose deprivation-induced cell death independently of inhibiting...
Evidence for decreased splanchnic glucose uptake after oral glucose administration in non-insulin-dependent diabetes mellitus
Hepatic glucose sensing is required to preserve β cell glucose competence - Infoscience
Aging | CTRP13 attenuates the expression of LN and CAV-1 Induced by high glucose via CaMKKβ/AMPK pathway in rLSECs -...
Postnatal Glucose Homeostasis in Late-Preterm and Term Infants | American Academy of Pediatrics
Plus it
Effect of alcohol and glucose infusion on pituitary-gonadal hormones in normal females<...
Neuromics: September 2015
Anticoagulant Citrate Dextrose Solution Formula B (Citric Acid; Dextrose; Sodium Citrate) Baxter
Utjecaj različitih koncentracija glukoze na aktivnost piruvat kinaze u HepG2 stanicama | Croatian Digital Theses Repository
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Team:University College London/Module 4 - 2012.igem.org
Team:University College London/Module 4 - 2012.igem.org
Cyclic AMP-Dependent Catabolite Repression Is the Dominant Control Mechanism of Metabolic Fluxes under Glucose Limitation in...
Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells |...
Accu Chek Active Glucose Monitor Online at Low Prices in India - Elawoman.com
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GENTAUR antibody-antibodies.com The Marketplace for Antibodies : Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated...
On-target action of anti-tropomyosin drugs regulates glucose metabolism | Garvan Institute of Medical Research
Glucose transporter - Wikipedia
Catabolite repression - Wikipedia
Glucose sensing through the Hxk2-dependent signalling pathway | Biochemical Society Transactions
Helena Malm | Lund University Diabetes Centre
Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling<...
Regional cerebral glucose metabolism during and after bilateral cerebral ischemia in the gerbil. | Stroke
Radiopharmaceuticals based on the glucose derivatives for tumor diagnosis<...
Serum glucose: Effects on tumor and normal tissue accumulation of 2-[F-18]-fluoro-2-deoxy-D-glucose in rodents with mammary...
The Brain Hypometabolism Hypothesis: Part 9 - Cerebral Metabolic Rate of Glucose - The Amazing World of Psychiatry: A...
Correlation Between the Interstitial and Arterial Glucose in Post Surgery Patients - Full Text View - ClinicalTrials.gov
SRC-1 Controls Livers Sweet Spot For Glucose Production - Redorbit
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Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4
Background Elevated glucose transporter 1 (GLUT1) expression and glucose utilization that | Thioredoxin Reductase and its...
Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p |...
Using dextrose (glucose) in cooking and baking - The ex-sugarholic
Using dextrose (glucose) in cooking and baking - The ex-sugarholic
Glucose phosphorylation as a barrier to muscle glucose uptake<...
Differential Effects of Oral , Peripheral Intravenous , and Intraportal Glucose on Hepatic Glucose Uptake and Insulin and...
Glucose-induced activation of pyruvate dehydrogenase in isolated rat pancreatic islets | Biochemical Journal
Impaired Glucose Transporter Activity in Pressure-Overload Hypertrophy Is an Early Indicator of Progression to Failure |...
The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose
Insulin receptor substrates-1 and -2 are both depleted but via different mechanisms after down-regulation of glucose transport...
Neuronal Cell Protective Effect of Dendropanax morbifera Extract against High Glucose-Induced Oxidative Stress | Korea Science
Clonal insulinoma cell line that stably maintains correct glucose responsiveness<...
Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene...
GW24-e3984 Effects of tetramethylpyrazine on human umbilical vein endothelial cells exposed to constant or intermittent high...
Acebutolol, a Cardioselective Beta Blocker, Promotes Glucose Uptake in Diabetic Model Cells by Inhibiting JNK-JIP1 Interaction
Glucose Uptake: Regulation, Signaling Pathways and Health Implications - Nova Science Publishers
The Effect of Noscapine on Oxygen-Glucose Deprivation on Primary Murine Cortical Neurons in High Glucose Condition
Oral glucose ingestion attenuates exercise-induced activation of 5-AMP-activated protein kinase in human skeletal muscle -...
The Study of HIV Protease Inhibitors and Their Effects on Glucose Metabolism - Full Text View - ClinicalTrials.gov
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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling
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The Ketogenic Diet for Health: February 2013
Acute Enterocyte Adaptation to Luminal Glucose: A Posttranslational Mechanism for Rapid Apical Recruitment of the Transporter...
DIABETES HYPOGLYCAEMIA EMERGENCY GLUCOSE KIT - HYPOWALLET - Healthy Senior Lifestyle
Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance and...
Glucose Metabolism in Abdominally Obese Hypertensive and Normotensive Subjects | Hypertension
Hyperglycemia as a Risk Factor for Cancer Progression
Leicester Research Archive: Modelling ischaemia in vitro: Effects of temperature and glucose concentration on dopamine release...
Effects of epigallocatechin-3-gallate on high glucose-induced glomerular epithelial cell damage::기초학문자료센터
Serval - Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.
Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K...
Altered proinsulin conversion in rat pancreatic islets exposed long-term to various glucose concentrations or interleukin-1β in...
Apelin targets gut contraction to control glucose metabolism via the brain | Gut
Tear glucose levels in normal people and in diabetic patients. | British Journal of Ophthalmology
Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells | Herb News
LCHF & Blood Glucose Fluctuations - Nutrition Network
Inhibition of cyclooxygenases attenuates diet-induced obesity and compensatory increased glucose-stimulated insulin secretion...
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia | JEM
Dysregulation of Glucose Transport, Glycolysis, TCA Cycle and Glutaminolysis by Oncogenes and Tumor Suppressors in Cancer Cells...
Intravenous therapy
Glucose[edit]. Intravenous glucose is used in some Asian countries such as Korea as a pick-me-up, for "energy," but is not a ... Asian immigrants to the United States are at risk if they seek intravenous glucose treatment. It may be had at store-front ... The person receives nutritional formulas containing salts, glucose, amino acids, lipids and added vitamins. ... Although many doctors warn Asian immigrants in New York that the effects of injecting glucose differ little from drinking ...
Mobile phone radiation and health
Glucose metabolism[edit]. According to the National Cancer Institute, two small studies exploring whether and how cell phone ...
Homeostasis
The fat cells take up glucose through special glucose transporters (GLUT4), whose numbers in the cell wall are increased as a ... Muscle cells also take glucose up through insulin-sensitive GLUT4 glucose channels, and convert it into muscle glycogen. ... Flat line is the set-point of glucose level and sine wave the fluctuations of glucose. ... Blood glucose[edit]. Main articles: Blood sugar regulation and Glycolysis § Regulation of the rate limiting enzymes ...
Vitamin B6
Glucose metabolism[edit]. PLP is a required coenzyme of glycogen phosphorylase, the enzyme necessary for glycogenolysis to ... Its active form, pyridoxal 5′-phosphate, serves as a coenzyme in some 100 enzyme reactions in amino acid, glucose, and lipid ... so deprivation of vitamin B6 results in impaired glucose tolerance.[4] ...
Citric acid cycle
Because two acetyl-CoA molecules are produced from each glucose molecule, two cycles are required per glucose molecule. ... Glucose feeds the TCA cycle via circulating lactate[edit]. The metabolic role of lactate is well recognized as a fuel for ... Glucose + 10 NAD+ + 2UQ + 2 ADP + 2 GDP + 4 Pi + 2 H2O. → 10 NADH + 2UQH2 + 10 H+ + 2 ATP + 2 GTP + 6 CO2 ... The total energy gained from the complete breakdown of one (six-carbon) molecule of glucose by glycolysis, the formation of 2 ...
Gestational diabetes
3 hour blood glucose level ≥140 mg/dl (7.8 mmol/L). An alternative test uses a 75 g glucose load and measures the blood glucose ... Oral glucose tolerance test[edit]. A standardized oral glucose tolerance test (OGTT)[45] should be done in the morning after an ... Non-challenge blood glucose tests[edit]. When a plasma glucose level is found to be higher than 126 mg/dl (7.0 mmol/l) after ... Oral glucose tolerance test (OGTT) A number of screening and diagnostic tests have been used to look for high levels of glucose ...
Basal metabolic rate
Glucose[edit]. Because the ratio of hydrogen to oxygen atoms in all carbohydrates is always the same as that in water-that is, ... Consequently, during the complete oxidation of a glucose molecule, six molecules of carbon dioxide and six molecules of water ...
Cortisol
... the breaking down of glycogen to glucose-1-phosphate and glucose. This is done through its passive influence on glucagon.[ ... and inhibits the peripheral use of glucose (insulin resistance)[14] by decreasing the translocation of glucose transporters ( ... Glucose[edit]. Cortisol counteracts insulin, contributes to hyperglycemia-causing hepatic gluconeogenesis[14] ... This response allows the liver to take up glucose not being used by the peripheral tissue and turn it into liver glycogen ...
Phosphorylation
By phosphorylating glucose (adding a negatively charged phosphate group), glucose is converted to glucose-6-phosphate and ... and the initial rate of phosphorylation of glucose is the rate-limiting step in glucose metabolism by the liver (ATP-D-glucose ... D-glucose + ATP → D-glucose-6-phosphate + ADP. ΔG° = −16.7 kJ/mol (° indicates measurement at standard condition). Researcher D ... High blood glucose releases insulin, stimulating the trans location of specific glucose transporters to the cell membrane.[11][ ...
Facilitated diffusion
For glucose[edit]. Glucose is a six-carbon sugar that provides energy needed by cells. Since glucose is a large molecule, it is ... Glucose, sodium ions, and chloride ions are just a few examples of molecules and ions that must efficiently cross the plasma ... The carrier protein at the membrane binds to the glucose and alters its shape such that it can easily to be transported from ... Thorens B (1993). "Facilitated glucose transporters in epithelial cells". Annu. Rev. Physiol. 55: 591-608. doi:10.1146/annurev. ...
Prediabetes
Impaired glucose tolerance[edit]. Main article: Impaired glucose tolerance. Impaired glucose tolerance (IGT) is a pre-diabetic ... Impaired fasting glucose is defined as a fasting glucose that is higher than the upper limit of normal, but not high enough to ... Two hour glucose tolerance test after ingesting the standardized 75 Gm glucose solution the blood sugar level of 140 to 199 mg/ ... Fasting blood glucose levels are in a continuum within a given population, with higher fasting glucose levels corresponding to ...
Endocrine disease
Glucose homeostasis disorders[edit]. *Diabetes *Type 1 Diabetes. *Type 2 Diabetes. *Gestational Diabetes ...
RAC1
... this allows for blood glucose to enter the cell to lower blood glucose. In conditions of obesity and type 2 diabetes, Rac1 ... Role in glucose transport[edit]. Rac1 is expressed in significant amounts in insulin sensitive tissues, such as adipose tissue ... given Rac1's role in glucose transport, drugs that inhibits Rac1 could potentially be harmful to glucose homeostasis. ... Rac1 protein is also necessary for glucose uptake in skeletal muscle activated by exercise[8][20] and muscle stretching[21] ...
Ghrelin
Glucose metabolism[edit]. The entire ghrelin system (dAG, AG, GHS-R and GOAT) has a gluco-regulatory action.[53] ... Ghrelin inhibits glucose-stimulated insulin secretion from beta cells in the pancreatic islets. Ghrelin does this indirectly by ... Heppner KM, Tong J (July 2014). "Mechanisms in endocrinology: regulation of glucose metabolism by the ghrelin system: multiple ... glucose output by primary hepatocytes". The Journal of Clinical Endocrinology and Metabolism. 90 (2): 1055-56. doi:10.1210/jc. ...
Human genetic resistance to malaria
Glucose-6-phosphate dehydrogenase (G6PD) is an important enzyme in red cells, metabolizing glucose through the pentose ... Glucose-6-phosphate dehydrogenase deficiency[edit]. Main article: Glucose-6-phosphate dehydrogenase deficiency ... Cappellini MD, Fiorelli G (January 2008). "Glucose-6-phosphate dehydrogenase deficiency". Lancet. 371 (9606): 64-74. doi: ... Some of these disorders are known by fanciful and cryptic names like sickle-cell anemia, thalassaemia, glucose-6-phosphate ...
Template:Glycolysis
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization ...
Acetyl-CoA
At low glucose levels: *CoA is acetylated using acetate by acetyl-CoA synthetase (ACS), also coupled with ATP hydrolysis.[7] ... At low glucose levels, the production of acetyl-CoA is linked to β-oxidation of fatty acids. Fatty acids are first converted to ... At high glucose levels, acetyl-CoA is produced through glycolysis.[10] Pyruvate undergoes oxidative decarboxylation in which it ... At high glucose levels, glycolysis takes place rapidly, thus increasing the amount of citrate produced from the tricarboxylic ...
Galactosemia
Lactose in food (such as dairy products) is broken down by the enzyme lactase into glucose and galactose. In individuals with ... Galactose is converted into glucose by the action of three enzymes, known as the Leloir pathway. There are diseases associated ... that checks for three enzymes that are needed to change galactose sugar that is found in milk and milk products into glucose, a ...
Tayberry
Glucose 1.86 g Fructose 2.35 g Water 85.75 g 2.7 Sugar 4.42 g ...
3-Phosphoglyceric acid
... (3PG) is the conjugate acid of glycerate 3-phosphate (GP). The glycerate is a biochemically significant metabolic intermediate in both glycolysis and the Calvin cycle. This anion is often termed PGA when referring to the Calvin cycle. In the Calvin cycle, 3-phosphoglycerate is the product of the spontaneous scission of an unstable 6-carbon intermediate formed upon CO2 fixation. Thus, two equivalents of 3-phosphoglycerate are produced for each molecule of CO2 that is fixed.[1][2] ...
Amylase
... yielding glucose. The γ-amylase has most acidic optimum pH of all amylases because it is most active around pH 3. They belong ... cleaving off two glucose units (maltose) at a time. During the ripening of fruit, β-amylase breaks starch into maltose, ... glucose and "limit dextrin" from amylopectin. They belong to glycoside hydrolase family 13. ... to hydrolyse dietary starch into disaccharides and trisaccharides which are converted by other enzymes to glucose to supply the ...
Standard enthalpy of formation
Glucose Solid C6H12O6 −1271 Isopropanol. Gas C3H7OH. −318.1 ...
Exercise
... lower fasting blood glucose". Medicine and Science in Sports and Exercise. 41 (8): 1606-14. doi:10.1249/MSS.0b013e31819dfe14. ... Endurance exercise before meals lowers blood glucose more than the same exercise after meals.[118] There is evidence that ...
Klebsiella aerogenes
Facultative anaerobic bacteria such as K. aerogenes have a theoretical maximum yield of 2 mol H2/mol glucose.[4] ... A theoretical maximum of 4 mol H2/mol glucose can be produced by strict anaerobic bacteria. ...
Blood test
While the regular glucose test is taken at a certain point in time, the glucose tolerance test involves repeated testing to ... "Glucose tolerance test". Medline. Retrieved June 21, 2012.. *^ C. A. Burtis and E. R. Ashwood, Tietz Textbook of Clinical ... Glucose (fasting). 70. 120. mg/dL. Common abbreviations[edit]. Upon completion of a blood test analysis, patients may receive a ... Glucose (fasting). 3.9. 5.8. mmol/L. See also glycated hemoglobin. ...
Benzaldehyde
This glycoside breaks up under enzyme catalysis into benzaldehyde, hydrogen cyanide and two equivalents of glucose. ...
Abductive logic programming
amount(lactose, hi), amount(glucose, low). }. Δ. 2. =. {. amount(lactose, medium), amount(glucose, medium). }. {\displaystyle ... glucose,low),amount(lactose,hi). express(lac(X)):-amount(glucose,medium),amount(lactose,medium). code(lac(y),permease). code( ... lac(z),galactosidase). temperature(low):-amount(glucose,low). Integrity constraints (IC). false :- amount(S,V1), amount(S,V2), ... of glucose are low and lactose are high or when they are both at medium level (see the fourth and fifth rule). The abducibles, ...
Isotretinoin
Increased blood glucose. *Haematuria. *Proteinuria. *Increased creatine phosphokinase. Possible permanent effects[edit]. ...
Microcephalin
Glucose tolerance test. Normal Auditory brainstem response. Abnormal DEXA. Normal Radiography. Normal ...
Anorexia nervosa
Glucose tolerance test: Oral glucose tolerance test (OGTT) used to assess the body's ability to metabolize glucose. Can be ... Lee H, Oh JY, Sung YA, Chung H, Cho WY (2009). "The prevalence and risk factors for glucose intolerance in young Korean women ...
Blood Test: Glucose (for Parents) - Nemours Kidshealth
The blood glucose test, which measures the amount of sugar in the blood, may be done as part of a routine physical or to help ... What Is a Glucose Test?. A glucose test measures how much glucose (GLOO-kose) is in the blood. Glucose is a type of sugar the ... Why Are Glucose Tests Done?. Doctors do glucose tests to check for low or high levels of glucose. Sometimes its done as part ... A low glucose level is called hypoglycemia. A high level of glucose is called hyperglycemia. Diabetes is one thing that can ...
Glucose syrup - Wikipedia
Glucose syrup, also known as confectioners glucose, is a syrup made from the hydrolysis of starch. Glucose is a sugar. Maize ( ... glucose.[4] Glucose syrup is used in foods to sweeten, soften texture and add volume. By converting some of the glucose in corn ... High-maltose glucose syrups[edit]. Main article: High maltose corn syrup. By using β-amylase or fungal α-amylase, glucose ... Glucose syrup containing over 90% glucose is used in industrial fermentation,[3] but syrups used in confectionery contain ...
Word! Glucose
... Glucose. Say: gloo-kose. When you eat, your body turns the food into a sugar called glucose. Like gas for a car ... The hormone insulin helps the glucose get to the cells, so it can be used for energy. ... glucose provides fuel for your cells. How does it get to the cells? Its carried to them by the bloodstream. ...
Glucose 6-phosphatase - Wikipedia
... glucose 6-phosphatase-α), glucose 6-transporter (G6PT), and glucose 6-phosphatase-β (glucose 6-phosphatase-β or G6PC3) subunits ... is an enzyme that hydrolyzes glucose 6-phosphate, resulting in the creation of a phosphate group and free glucose. Glucose is ... Wikimedia Commons has media related to Glucose 6-phosphatase.. *Glucose-6-Phosphatase at the US National Library of Medicine ... In this model, glucose 6-phosphatase has a low degree of selectivity. The transfer of the glucose 6-phosphate is carried out by ...
glucose (CHEBI:17234)
aldehydo-glucose (CHEBI:37663) is a glucose (CHEBI:17234). D-glucose (CHEBI:17634) is a glucose (CHEBI:17234). L-glucose (CHEBI ... glucose (CHEBI:17234) has role fundamental metabolite (CHEBI:78675) glucose (CHEBI:17234) is a aldohexose (CHEBI:33917) ... thioglucoside (CHEBI:9553) has functional parent glucose (CHEBI:17234). molasses (CHEBI:83163) has part glucose (CHEBI:17234). ... CHEBI:17234 - glucose. Main. ChEBI Ontology. Automatic Xrefs. Reactions. Pathways. Models. .gridLayoutCellStructure { min-width ...
Glucose levels in babies
... glucose levels in babies, quick ways to lower blood sugar naturally cinnamon, what does it mean if my glucose is low, what ... causes low glucose serum, blood sugar regulation disorders, what causes low blood sugar not diabetic 400g, normal blood sugar ... Glucose levels in babies,diabetes blood test results 5.7,what causes high blood sugar readings,glucose range non fasting vs - ... Oranges starting glucose level was different between the two meals (as is typical when comparing fasting glucose levels that ...
glucose | University of Cambridge
Hometesting diabetic cat's blood glucose - YouTube
Home testing a diabetic cats blood glucose (BG), or blood sugar levels using an ear poke with a lancet pen, and a glucometer. ... Cat Diabetes Glucose Testing - Duration: 4:13. Ask the Cat Doctor 26,275 views ... Testing blood glucose in a cat- Part 3 - Duration: 4:25. FrangipaniSal 355 views ... Home testing a diabetic cats blood glucose (BG), or blood sugar levels using an ear poke with a lancet pen, and a glucometer. ...
Definition: Glucose (for Parents) - Nemours
Glucose is the main type of sugar in the blood and is the major source of energy for the bodys cells. ... Definition: Glucose. Glucose. Glucose is the main type of sugar in the blood and is the major source of energy for the bodys ... Glucose comes from the foods we eat or the body can make it from other substances. Glucose is carried to the cells through the ...
Word! Glucose (for Kids) - Nemours
... your body turns the food into a sugar called glucose. Like gas for a car, glucose provides fuel for your cells. ... Glucose. Say: gloo-kose. When you eat, your body turns the food into a sugar called glucose. Like gas for a car, glucose ... The hormone insulin helps the glucose get to the cells, so it can be used for energy. ...
alpha-D-glucose (CHEBI:17925)
D-glucose (CHEBI:17925). α-D-glucose 1-phosphate (CHEBI:29042) has functional parent α-D-glucose (CHEBI:17925). α-D-glucose 3- ... α-D-glucose (CHEBI:17925) is a D-glucopyranose (CHEBI:4167) α-D-glucose (CHEBI:17925) is enantiomer of α-L-glucose (CHEBI:37630 ... 2-deoxy-2-fluoro-α-D-glucose (CHEBI:49132) has parent hydride α-D-glucose (CHEBI:17925). α-L-glucose (CHEBI:37630) is ... D-glucose (CHEBI:17925). 2,6-diamino-2,6-dideoxy-α-D-glucose (CHEBI:41105) has functional parent α-D-glucose (CHEBI:17925). 4-O ...
Hyperglycemia (High Blood Glucose) | ADA
Glucose-galactose malabsorption: MedlinePlus Genetics
... the sugars glucose and galactose, which primarily results in severe diarrhea. Explore symptoms, inheritance, genetics of this ... Glucose-galactose malabsorption is a condition in which the body cannot take in (absorb) ... Glucose-galactose malabsorption is a condition in which the body cannot take in (absorb) the sugars glucose and galactose, ... Glucose and galactose are simple sugars; they are present in many foods, or they can be obtained from the breakdown of lactose ...
Hypoglycemia (Low Blood Glucose) | ADA
If blood sugar stays low for too long, starving the brain of glucose, it may lead to seizures, coma, and very rarely death. ... A continuous glucose monitor can sound an alarm when blood sugar levels are low or start to fall. This can be a big help for ... If the blood sugar level continues to drop, the brain does not get enough glucose and stops functioning as it should. This can ... Liquids are absorbed much faster than solids, so timing the insulin dose to the absorption of glucose from foods can be tricky ...
World Glucose Self-Testing Markets
12, 2014-- Research and Markets has announced the addition of the World Glucose Self-Testing Markets report to their offering ... As such, the global market for blood glucose self-testing products is... ... 4. Glucose Monitoring Recommendations 5. Glucose Self-testing Technology Platforms and Consumable Products 6. Glucose Self- ... As such, the global market for blood glucose self-testing products is undergoing a significant transition driven by the advent ...
Magnesium and glucose homeostasis | SpringerLink
Magnesium insulin glucose homeostasis diabetic complications dietary magnesium supplements Download to read the full article ... Curry DL, Joy RM, Holley DC, Bennett LL (1977) Magnesium modulation of glucose-induced insulin secretion by the perfused rat ... Rosenbloom AL (1977) Serum calcium and magnesium decline during oral glucose tolerance testing in children and adolescent with ... Legrand C, Okitolonda W, Pottier AM, Lederer J, Henquin JC (1987) Glucose homeostasis in magnesium-deficient rats. Metabolism ...
glucose Archives - ExtremeTech
One Drop Blood Glucose Monitoring Kit - Apple
The compact One Drop Chrome blood glucose monitoring kit lets you measure your glucose levels and then track them on your ... Sync your meter with the One Drop Mobile app on your iPhone or Apple Watch to see all your blood glucose data and analytics at ... Blood glucose meter Proprietary technology ensures clinically proven accurate, reliable results in just five seconds. The meter ... Wirelessly transmits blood glucose data via Bluetooth to the One Drop app on your iPhone or Apple Watch ...
One Drop Blood Glucose Monitoring Kit - Apple
The compact One Drop Chrome blood glucose monitoring kit lets you measure your glucose levels and then track them on your ... FANTASTIC GLUCOSE METER!. From someone who has used this meter all the time for the last 2-3 years, this product is very well- ... FANTASTIC GLUCOSE METER!. From someone who has used this meter all the time for the last 2-3 years, this product is very well- ... Sync your meter with the One Drop Mobile app on your iPhone or Apple Watch to see all your blood glucose data and analytics at ...
Amazon Best Sellers: Best Blood Glucose Monitors
Discover the best Blood Glucose Monitors in Best Sellers. Find the top 100 most popular items in Amazon Health & Personal Care ... Blood Glucose W/Glucose SOS Dextrose Powder, A Natural Alternative to Glucose Gel and Glucose Tablets for Blood Sugar - Glucose ... Dario Blood Glucose Test Strips for The Dario and Dario LC Blood Glucose Monitoring System. Great for Diabetics to Keep Track ... Dario Blood Glucose Monitor Kit Test Your Blood Sugar Levels and Estimate A1c. Kit Includes: Glucose-Meter with 25 Strips,10 ...
Glucose
D-Glucose, anhydrous; Dextrose, anhydrous; Glucose (D); Glucose, anhydrous; Glucose liquid; Blood sugar; Roferose ST; Cerelose ... Other names: D-Glucose; Anhydrous dextrose; Cartose; Cerelose; Corn sugar; D-(+)-Glucose; Dextropur; Dextrose; Dextrosol; ... 2001; Glucosteril; Goldsugar; Maxim Energy Gel; Staleydex 111; Staleydex 333; Tabfine 097(HS); Vadex; (+)-Glucose ...
GLUCOSE
Glucose repression in yeast. - PubMed - NCBI
Glucose repression in yeast.. Carlson M1.. Author information. 1. Departments of Genetics and Development and Microbiology, ... The Snf1 protein kinase is a central component of the signaling pathway for glucose repression in yeast. Recent studies have ... the regulation of Snf1 kinase activity and elucidated mechanisms by which Snf1 controls repression and activation of glucose- ...
Intensive Glucose Control Lowers Microvascular Risks
Patients with type 2 diabetes who undergo intensive glucose lowering have a reduced risk of developing microvascular kidney and ... Intensive glucose control was associated with a 20% lower risk for kidney events and a 13% lower risk for eye events. There was ... More intensive glucose control resulted in a pooled absolute difference in mean HbA1c compared with less intensive control of - ... More intensive glucose control was associated with a significant reduction in the relative risk for the composite primary ...
Patent US7005048 - Glucose sensor - Google Patents
... and a reaction layer containing at least pyrrolo-quinoline quinone dependent glucose dehydrogenase, formed in contact with or ... The present invention provides a high-performance glucose sensor having excellent storage stability and an improved response ... A glucose sensor was fabricated in such a manner.. Next, as a sample solution, blood conditioned to have a glucose ... For instance, if glucose oxidase is selected as the enzyme, it is possible to fabricate a glucose sensor for measuring the ...
What Products Is Glucose In? | eHow
Honey is also a natural source of glucose.. Baked Goods. Glucose syrup is used in the production of baked goods such as cookies ... Glucose is the main source of energy used by the human body. In the United States the main source of glucose used in food ... Foods Naturally Containing Glucose. Glucose occurs naturally in the sap of most plants but is found in significant amounts in ... Most processed sweets contain glucose as their main source of sugar. Glucose syrup is widely used both for its sweet taste and ...
How do blood glucose monitors work?
Blood glucose meters measure blood glucose levels electronically. Such measurement utilizes only a small drop of blood from the ... Determination of plasma glucose during rapid glucose excursions with a subcutaneous glucose sensor. Diabetes Technol Ther. 2003 ... Blood glucose meters measure blood glucose levels electronically. Such measurement utilizes only a small drop of blood from the ... How do blood glucose monitors work?. Updated: Jan 22, 2020 * Author: Benjamin Daniel Liess, MD; Chief Editor: George T Griffing ...
Glucagon & Other Emergency Glucose Products | ADA
... having access to emergency fast-acting glucose products is critical. Learn whats in a glucagon kit, how to administer it, and ... When you have severe hypoglycemia, it means you cant swallow glucose-containing foods or drinks on your own to bring your ... Glucose is taken as a spray into the nose or an injection administered under the skin. ... Diabetes is a balancing act, especially when you take insulin or oral medications that lower blood sugar (blood glucose), ...
Possible Link Between Brain Glucose, Alzheimer's
Institutes of Health says scientists have found a connection between abnormalities in how the brain breaks down glucose. ... A study finds higher brain glucose levels could play a role. by Brandon Gobel, AARP, November 10, 2017 , Comments: 0 ... Glucose metabolism provides the fuel for physiological brain function. The brain is the most energy-demanding organ. It uses ... "For the first time, scientists have found a connection between abnormalities in how the brain breaks down glucose and the ...
Patent US5964993 - Glucose sensor - Google Patents
A sensor that is capable of accurately measuring glucose and other analytes in low oxygen environments is provided. The sensor ... implanting a glucose sensor within a subject whose glucose level is to be monitored, wherein the glucose sensor includes a ... A subjects glucose level can be determined by using the glucose sensor of the present invention by situating the glucose ... Glucose sensors are used to measure glucose levels within a subjects body tissues. The glucose sensor of the present invention ...
Impaired glucose tMetabolismSugarLevels of glucose2018MeterOxidaseRegulating glucose levelsInsulin secretionPeople with diabetesBloodstreamSensorMonosaccharideDextroseDehydrogenaseType 1 diabetMetersStripsHypoglycemiaDiabeticHyperglycemiaHigher-than-normal blood glucose levelsConcentrationIntoleranceCapillaryResearchersMonitor their blood glucose levelsAffecting your blood glucose levelsDiabeticsMonitoringEnzymesMoleculePlasma glucoseOxygenGlycogenPostprandial glucoseCarbohydrateUrineReadingsUptakeMonitorsLevelIncreasesNaturallyMealsBrain breaks down glucoseBody'sHigh glucose levelsProduction of glucoseHttpsReplace fingerstickStarchMmolSyrupForm of glucoseStructure of glucoseNormalComplications
Impaired glucose t13
- Also known as impaired glucose tolerance, it is a term used to denote a pre-diabetic state of hyperglycemia. (buzzle.com)
- If you are diagnosed with impaired glucose tolerance, the preceding stage to diabetes, the guidelines from this article will be helpful to you. (buzzle.com)
- The study in Daqing showed how lifestyle changes can prevent type 2 among people with impaired glucose tolerance, which is sometimes a prelude to the condition. (merriam-webster.com)
- A blood glucose level between 140 and 199 mg/dL (7.8 and 11 mmol/L) is considered impaired glucose tolerance, or prediabetes. (mayoclinic.org)
- Impaired Glucose Tolerance (IGT) is a medical condition in which a person has higher than normal blood glucose levels but below the level of diabetes. (selfgrowth.com)
- According to WHO impaired glucose tolerance may be defined as two-hour glucose levels of 140 to 199 mg per dL (7.8 to 11.0 mmol) on the 75-g oral glucose tolerance test. (selfgrowth.com)
- Patients suffering from Impaired Glucose Tolerance are at higher risk of developing Type 2 diabetes. (selfgrowth.com)
- Impaired Glucose Tolerance cannot be diagnosed easily as generally it does not show any symptoms or at least pronounced symptoms. (selfgrowth.com)
- Thus without diagnosis, it is not possible to treat impaired glucose tolerance. (selfgrowth.com)
- Patients with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) are at higher risk for diabetes. (selfgrowth.com)
- For diagnosis of impaired glucose tolerance or pre-diabetes two different blood tests are done. (selfgrowth.com)
- After a patient is diagnosed with impaired glucose tolerance or impaired fasting glucose is made, he needs to amend his lifestyle to reduce the risk of developing Type II Diabetes. (selfgrowth.com)
- If the fasting reading is between 100 and 125 mg/dL, there's a change you have impaired glucose tolerance, otherwise known as prediabetes. (healthline.com)
Metabolism15
- Glucose metabolism provides the fuel for physiological brain function. (aarp.org)
- They theorized that the influence of a hot bath over glucose metabolism might revolve around the inflammatory response. (medicalnewstoday.com)
- The most notable change in the metabolic profile of hypertrophied hearts is an increased reliance on glucose with an overall reduced oxidative metabolism, i.e. a reappearance of the foetal metabolic pattern. (nih.gov)
- Aside from increased reliance on glucose as an energy source, changes in other glucose metabolism pathways, e.g. the pentose phosphate pathway, the glucosamine biosynthesis pathway, and anaplerosis, are also noted in the hypertrophied hearts. (nih.gov)
- Studies using transgenic mouse models and pharmacological compounds to mimic or counter the switch of substrate preference in cardiac hypertrophy have demonstrated that increased glucose metabolism in adult heart is not harmful and can be beneficial when it provides sufficient fuel for oxidative metabolism. (nih.gov)
- Sirtuins in glucose and lipid metabolism. (nih.gov)
- In this review, we summarize the background of glucose and lipid metabolism concerning sirtuins and discuss the functions of sirtuins in glucose and lipid metabolism. (nih.gov)
- SIRT6 plays important roles in several pathways concerning glucose and lipid metabolism. (nih.gov)
- Galli's group was among the first to show that insulin - the hormone that governs glucose metabolism in the body - also regulates the brain's supply of dopamine, a neurotransmitter with roles in motor activity, attention and reward. (psychcentral.com)
- In type 2 diabetics this glucose metabolism brain control is often dysfunctional. (news-medical.net)
- Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have discovered neural mechanisms in mice specific to females that can shift estrogen from playing a protective role in glucose metabolism to one that is disruptive. (news-medical.net)
- In energy metabolism, glucose is the most important source of energy in all organisms. (wikipedia.org)
- Glucose for metabolism is stored as a polymer, in plants mainly as starch and amylopectin, and in animals as glycogen. (wikipedia.org)
- For the discovery of the metabolism of glucose Otto Meyerhof received the Nobel Prize in Physiology or Medicine in 1922. (wikipedia.org)
- In 1947, Bernardo Houssay (for his discovery of the role of the pituitary gland in the metabolism of glucose and the derived carbohydrates) as well as Carl and Gerty Cori (for their discovery of the conversion of glycogen from glucose) received the Nobel Prize in Physiology or Medicine. (wikipedia.org)
Sugar68
- Glucose is a type of sugar the body uses for energy. (kidshealth.org)
- Glucose is a sugar . (wikipedia.org)
- When you eat, your body turns the food into a sugar called glucose. (kidshealth.org)
- The hydrolysis of glucose 6-phosphate begins with a nucleophilic attack on the sugar-bound phosphate by His176 resulting in the formation of a phosphohistidine bond and the degradation of a carbonyl. (wikipedia.org)
- Home testing a diabetic cat's blood glucose (BG), or blood sugar levels using an ear poke with a lancet pen, and a glucometer. (youtube.com)
- Glucose is the main type of sugar in the blood and is the major source of energy for the body's cells. (kidshealth.org)
- Hyperglycemia is the technical term for high blood glucose (blood sugar). (diabetes.org)
- Small amounts of the simple sugar glucose in the urine (mild glucosuria) may occur in this disorder. (medlineplus.gov)
- These foods contain glucose, galactose, and another sugar called lactose that gets broken down into these two sugars. (medlineplus.gov)
- The SGLT1 protein transports glucose into specialized kidney cells, ensuring that the sugar goes back into the bloodstream and is not released into the urine. (medlineplus.gov)
- Throughout the day, depending on multiple different factors, blood sugar (also called blood glucose) levels will vary - up or down. (diabetes.org)
- If the blood sugar level continues to drop, the brain does not get enough glucose and stops functioning as it should. (diabetes.org)
- If blood sugar stays low for too long, starving the brain of glucose, it may lead to seizures, coma, and very rarely death. (diabetes.org)
- Glucagon is a hormone produced in the pancreas that stimulates your liver to release stored glucose into your bloodstream when your blood sugar levels are too low. (diabetes.org)
- One is designing a glucose-responsive insulin (GRI) that will circulate through the bloodstream, turning on when it's needed to control blood sugar and turning off when blood sugar starts to go low. (jdrf.org)
- A successful GRI would keep tight control over blood sugar, reduce the need for glucose monitoring and probably require fewer doses to maintain control throughout the day. (jdrf.org)
- As you probably know, from sucking down cans of Coke and masticating on candy, sugar - glucose, fructose, sucrose, dextrose - is an excellent source of energy. (extremetech.com)
- Dario Blood Glucose Monitor Kit Test Your Blood Sugar Levels and Estimate A1c. (amazon.com)
- For those of you who are familiar with diabetes and the other factors related to diabetes, A1C level is the measurement of how good your body process blood sugar, or glucose, in your system, using its own insulin. (amazonaws.com)
- Glucose is a simple sugar and natural sweetener that is found naturally in many foods and added to processed foods and other goods. (ehow.com)
- Glucose syrup is used in the production of baked goods such as cookies, crackers, pies and pastries because it results in a desirable color, texture and taste in comparison with other types of sugar. (ehow.com)
- Most processed sweets contain glucose as their main source of sugar. (ehow.com)
- Diabetes is a balancing act, especially when you take insulin or oral medications that lower blood sugar (blood glucose), especially sulfonylureas. (diabetes.org)
- As researchers work to find better ways to treat Alzheimer's disease and delay its onset, they've come across a possible connection involving levels of glucose, a form of sugar, in people's brain. (aarp.org)
- Glucose test strips make it easy for diabetics and those diagnosed with low blood sugar levels to monitor their blood sugar throughout the day. (staples.com)
- That fast response time is convenient, especially if you're measuring blood sugar during a medical emergency and need to quickly administer glucose. (staples.com)
- Continuous glucose monitoring automatically tracks blood glucose levels, also called blood sugar, throughout the day and night. (nih.gov)
- Blood sugar is the concentration of glucose in the body, explains Dr Rai, and it's used for energy. (netdoctor.co.uk)
- Also known as the plasma glucose level, blood sugar is expressed in millimoles per litre (mmol/l). (netdoctor.co.uk)
- Not only does glucose come from the food we eat, but the body creates it by digesting foods, such as carbohydrates , into a sugar that circulates in the bloodstream. (netdoctor.co.uk)
- Low blood sugar, also known as hypoglycaemia, is what happens when the glucose in your blood drops too low, says Dr Basford. (netdoctor.co.uk)
- Treat hypoglycemia by raising your blood glucose level with some form of sugar. (archive.org)
- The quickest way to raise your blood glucose and treat hypoglycemia is with some form of sugar. (archive.org)
- a sugar, C 6 H 12 O 6 , having several optically different forms, the common dextrorotatory form ( dextroglucose, or d -glucose ) occurring in many fruits, animal tissues and fluids, etc., and having a sweetness about one half that of ordinary sugar, and the rare levorotatory form ( levoglucose, or l -glucose ) not naturally occurring. (dictionary.com)
- The cells in your body run on glucose from sugar and ketones from fat. (dictionary.com)
- Manufacturers found that by adding chemicals, or sugar and glucose during the boiling off, they could make up for this loss. (dictionary.com)
- Glucose is a product of photosynthesis, mostly incorporated into the disaccharide sugar sucrose rather than circulating free in the plant. (dictionary.com)
- Checking blood glucose with a meter only provides information about the blood sugar level at that specific point in time. (umassmed.edu)
- A machine that helps test how much glucose ( sugar ) is in the blood . (everything2.com)
- The glucose tolerance test, also known as the oral glucose tolerance test, measures your body's response to sugar (glucose). (mayoclinic.org)
- People with diabetes suffer from elevated levels of blood sugar or glucose. (cvs.com)
- You can take glucose tablets to quickly supply your body with sugar and bring your numbers closer to normal range. (cvs.com)
- He or she can recommend what steps to take when you experience low blood sugar levels and help you decide if glucose tablets are the best solution for hypoglycemia for you. (cvs.com)
- They get turned into energy very quickly so your blood glucose (sugar) levels go up very quickly. (diabetes.org.uk)
- A CSF glucose test measures the amount of sugar (glucose) in the cerebrospinal fluid (CSF). (ucsfhealth.org)
- The glucose level in the CSF should be 50 to 80 mg/100 mL (or greater than 2/3 of the blood sugar level). (ucsfhealth.org)
- Their glucose levels are often measured via blood sugar test kits, which involve pricking the finger to get a blood sample for testing. (naturalnews.com)
- The glucose urine test measures the amount of sugar (glucose) in a urine sample. (ucsfhealth.org)
- If you have diabetes, purchasing a blood glucose meter (or glucometer) is one of the best and most important ways to monitor your blood sugar at home. (wikihow.com)
- Jun 25, 2019 (News AIM via COMTEX) -- Glucose sensors are inserted under skin to measure glucose (sugar) levels. (marketwatch.com)
- This leaves more sugar, or glucose, in your blood. (healthline.com)
- If you check your blood sugar and find you have hypoglycemia, eat some hard candy or glucose tablets. (healthline.com)
- Glucose testing is a random blood test to check glucose (sugar) levels. (healthline.com)
- In adults without diabetes, glucose levels are managed through the actions of our internal insulin and the body's use of sugar for energy. (healthline.com)
- If you have limited or no sight, talking blood glucose meters are the key to checking your blood sugar readings independently. (consumersearch.com)
- A continuous glucose monitor holds a tiny sensor that's inserted just under the skin, alleviating the need for patients to prick their fingers every day to check blood sugar. (theepochtimes.com)
- There's little evidence that continuous glucose monitoring (CGM) leads to better outcomes for the estimated 25 million U.S. patients with Type 2 diabetes who don't inject insulin to regulate their blood sugar, health experts say. (theepochtimes.com)
- Doctors often recommend that diabetes patients test their glucose at home to track whether they are reaching treatment goals and learn how medications, diet, exercise, and stress affect blood sugar levels. (theepochtimes.com)
- Instead, they measure the interstitial glucose level, which is the sugar level found in the fluid between the cells. (theepochtimes.com)
- Glucose is a moderately sweet sugar that is found in fruits and vegetables. (reference.com)
- The consensus among biochemists is that virtually every cell in the human body can break down sugar, usually in the form of glucose, to use as energy. (reference.com)
- Glucose is a form of carbohydrate known as a simple sugar, or monosaccharide. (reference.com)
- Glucose is a monosaccharide, or simple sugar, a class of molecules that forms 5- and 6-sided rings, not unlike a benzene ring. (ehow.co.uk)
- Glucose is a simple sugar with the molecular formula C6H12O6. (wikipedia.org)
- Glucose circulates in the blood of animals as blood sugar. (wikipedia.org)
- Glucose, as intravenous sugar solution, is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. (wikipedia.org)
- Glucose was discovered in grapes by Johann Tobias Lowitz in 1792, and distinguished as being different from cane sugar (sucrose). (wikipedia.org)
- In 1970, Luis Leloir was awarded the Nobel Prize in Chemistry for the discovery of glucose-derived sugar nucleotides in the biosynthesis of carbohydrates. (wikipedia.org)
Levels of glucose3
- Doctors do glucose tests to check for low or high levels of glucose. (kidshealth.org)
- Sweet foodstuffs like blended juices, canned fruits, carbonated beverages and other soft drinks, sweetened cereals and yogurt contain high levels of glucose as the source of their sweetness. (ehow.com)
- We measured levels of glucose and oxygen while people were doing mental tasks and found both levels fell," Scholey says. (go.com)
20182
- For instance, in April 2018, University of California San Diego, in collaboration with National Institutes of Health (NIH), initiated the clinical study for adhesive glucose sensor to measure sweat glucose of patients with diabetes. (marketwatch.com)
- For instance, in July 2018, Abbott Laboratories received the U.S. Food and Drug Administration (FDA) approval for its FreeStyle Libre 14 day Flash Glucose Monitoring System. (marketwatch.com)
Meter21
- The meter then wirelessly transmits that blood glucose data via Bluetooth to the One Drop Mobile app on your iOS device. (apple.com)
- Sync your meter with the One Drop Mobile app on your iPhone or Apple Watch to see all your blood glucose data and analytics at a glance. (apple.com)
- The digital meter obtains information from the blood on the strip, and within seconds, the glucose level is displayed on the screen. (medscape.com)
- iBGStar (Sanofi) is the first blood glucose meter to connect directly to iPhone and iPod Touch. (medscape.com)
- I have been using a glucose meter that I was prescribed and there are days where my glucose have been what I consider to be normal, then there are days where I will run low an hour after meals or in the middle of the night. (medhelp.org)
- You'll test a drop of blood on a standard glucose meter. (nih.gov)
- CGM glucose readings need to be checked against a standard glucose meter twice a day. (nih.gov)
- But you still need a finger-stick glucose test twice a day to check the accuracy of your CGM against a standard blood glucose meter. (nih.gov)
- Buying the right glucose meter may seem daunting, but it's simple enough when you consider your unique needs, get helpful advice, and keep costs at a minimum. (wikihow.com)
- To narrow down what you need, make a list of the top 5 most important aspects that you're looking for in a glucose meter. (wikihow.com)
- Oftentimes choosing a glucose meter is based on personal preference, but some doctors may be able to make recommendations for you. (wikihow.com)
- By taking the time to check into consumer ratings and comments, you can avoid investing in a glucose meter that fails to live up to the promises made by the manufacturer. (wikihow.com)
- Ask your doctor if functions like these are important for you to have in your glucose meter. (wikihow.com)
- For some patients, being able to check for ketones in their blood is a necessary function of a glucose meter. (wikihow.com)
- Measure the glucose concentration of (the reagent area) containing the required capillary blood with a glucose meter. (slideshare.net)
- However, just being able to speak your readings out loud isn't enough to make a blood glucose meter truly accessible to those with limited vision. (consumersearch.com)
- One blood glucose meter, however, stands out as offering everything you need for truly accessible blood glucose testing: The Prodigy Voice (Est. (consumersearch.com)
- CONTOUR® Blood Glucose Test Strips for use with CONTOUR® Blood Glucose Meter. (walgreens.com)
- Ascensia Diabetes Care Inc USA does not warrant use of the CONTOUR® Blood Glucose Meter with any strip other than CONTOUR® Blood Glucose Strips. (walgreens.com)
- They use audible messages to coach you through the process of setting your meter up, testing your blood glucose levels and recording the results. (consumersearch.com)
- Just because a home blood glucose meter meets the current federal standards doesn't mean it's the best. (consumersearch.com)
Oxidase8
- 8. The membrane of claim 7 wherein the oxidase is glucose oxidase. (google.com)
- 20. The membrane system of claim 19 wherein the oxidase is glucose oxidase. (google.com)
- 27. The glucose sensor of claim 26 wherein the enzyme is an oxidase. (google.com)
- 28. The glucose of claim 27 wherein the oxidase is glucose oxidase. (google.com)
- A sterile lancet NOTE The reagent strip contains the enzymes glucose oxidase and peroxidase, together with3. (slideshare.net)
- The glucose oxidase reacts4. (slideshare.net)
- A nanocomposite containing amine functionalized multiwalled carbon nanotubes and a room temperature ionic liquid (1-butyl-3-methylimidazolium tetrafluoroborate) was prepared and applied for glucose oxidase (GOx) immobilization on glassy carbon electrode. (hindawi.com)
- Wang and Musameh [ 2 ] reported the first CNTs/enzyme electrodes for glucose and ethanol by incorporating glucose oxidase (GOx) and alcohol dehydrogenase within a three-dimensional CNTs/Teflon matrix. (hindawi.com)
Regulating glucose levels1
- In other words, no bacteria, no problem regulating glucose levels. (newscientist.com)
Insulin secretion10
- Glucose toxicity is a well-established entity that has been shown in animal models of diabetes to contribute to development of insulin resistance and impaired insulin secretion. (diabetesjournals.org)
- In type II (non-insulin-dependent) diabetes in humans, a considerable body of evidence has accumulated indicating that a chronic physiological increment in the plasma glucose concentration leads to progressive impairment in insulin secretion and may contribute to insulin resistance as well. (diabetesjournals.org)
- Evidence also has accumulated to implicate glucose toxicity in the functional impairment in insulin secretion that occurs during the initial presentation of patients with type I diabetes, and this may explain the honeymoon period so commonly observed after the institution of insulin therapy. (diabetesjournals.org)
- Weight loss and increased physical activity help in reducing insulin resistance and help in restoring the normal insulin secretion, thus blood glucose level is controlled and stays within normal limits. (selfgrowth.com)
- In many organisms, normoglycemia is achieved by a tight coupling of nutrient-stimulated insulin secretion in the pancreatic β-cell (acute insulin response [AIR]) and the metabolic action of insulin to stimulate glucose disposal (insulin action [ M ]). It is widely accepted that in healthy individuals with normal glucose tolerance, normoglycemia can always be maintained by compensatorily increasing AIR in response to decreasing M (and vice versa). (diabetesjournals.org)
- In people with normal glucose tolerance (NGT), a decrease in insulin action ( M ) is accompanied by upregulation of insulin secretion (and vice versa). (diabetesjournals.org)
- Insulin secretion is primarily substrate controlled, and glucose, the preeminent secretagogue among nutrient molecules, would be a good candidate for such a signal. (diabetesjournals.org)
- Glucose-stimulated insulin secretion is primarily controlled by the enzyme glucokinase, which governs the generation of energy from glucose and acts as the β-cell glucose sensor ( 6 ). (diabetesjournals.org)
- If glucose were indeed one of the signals linking insulin resistance and β-cell compensation, insulin secretion should not fully compensate for worsening insulin resistance, since this would remove the stimulus for the compensation. (diabetesjournals.org)
- Increased extracellular glucose stimulates firing of a subset of proopiomelanocortin (POMC)-containing neurons in the hypothalamus through a mechanism thought to depend, like insulin secretion in pancreatic β cells, on the adenosine 5′-triphosphate (ATP)-dependent closure of ATP-sensitive potassium (K ATP ) channels in the plasma membrane. (sciencemag.org)
People with diabetes7
- Over time, good management of glucose greatly helps people with diabetes stay healthy and prevent complications of the disease. (nih.gov)
- Many people with diabetes like to carry glucose tablets. (archive.org)
- Amanda Morris, azcentral , "He's the oldest-known man with rare Proteus syndrome and he hopes to help find a cure," 28 Jan. 2020 People with diabetes have higher-than-normal glucose levels in their blood, and depend on prescription insulin to regulate those levels and prevent potentially life-threatening complications. (merriam-webster.com)
- The second part provides specific weight loss recommendations, tips for athletes who want energy to fuel their exercise, and for people with diabetes to control their blood glucose. (mendosa.com)
- The idea that a surrogate for blood glucose could be measured by the glucose level in tears seemed to excite both the media and people with diabetes and physicians. (healthcentral.com)
- Random glucose testing is a powerful tool for people with diabetes. (healthline.com)
- In people with diabetes and prediabetes , glucose levels can vary widely over the course of the day. (healthline.com)
Bloodstream4
- Glucose is carried to the cells through the bloodstream. (kidshealth.org)
- however, other proteins in the kidneys are able to absorb enough glucose into the bloodstream, so that glucosuria is mild, if present at all, in people with glucose-galactose malabsorption. (medlineplus.gov)
- The insulin allows the glucose to enter the bloodstream and be used for energy. (healthline.com)
- Glucose is absorbed directly into the bloodstream, as it requires no digestion. (reference.com)
Sensor24
- The present invention provides a high-performance glucose sensor having excellent storage stability and an improved response characteristic. (google.com)
- and a reaction layer formed in contact with or in the vicinity of said electrode system, wherein said reaction layer contains an admixture of at least pyrrolo-quinoline quinone dependent glucose dehydrogenase and potassium gluconate and wherein the glucose sensor is in a sealed container. (google.com)
- 2. The glucose sensor as set forth in claim 1 , wherein said reaction layer further contains at least one additive selected from the group consisting of phthalic acid, salts of phthalic acid, maleic acid, salts of maleic acid, succinic acid and salts of succinic acid. (google.com)
- 3. The glucose sensor as set forth in claim 2 , wherein said reaction layer further contains calcium ions. (google.com)
- 4. The glucose sensor as set forth in claim 2 , wherein said reaction layer further contains an electron mediator. (google.com)
- 9. The glucose sensor as set forth in claim 1 wherein the amount of potassium gluconate is within the range of 1.5 to 150 μg and the amount of glucose dehydrogenase is 0.2 to 20 U. (google.com)
- and a reaction layer formed in contact with or in the vicinity of said electrode system, wherein said reaction layer contains an admixture of at least pyrrolo-quinoline quinone dependent glucose dehydrogenase and potassium gluconate, wherein the response of the sensor immediately fabricated is substantially the same as compared to the sensor after being stored for one week at 40 C. (google.com)
- 11. The glucose sensor as set forth in claim 10 in a sealed container. (google.com)
- A sensor that is capable of accurately measuring glucose and other analytes in low oxygen environments is provided. (google.com)
- 23. The glucose sensor of claim 22 wherein the outer membrane of the membrane system comprises polycarbonate. (google.com)
- 24. The glucose sensor of claim 22 wherein the silicon compound of the enzyme-containing membrane is a cross-linked polyorganosiloxane. (google.com)
- 25. The glucose sensor of claim 24 wherein the polyorganosiloxane is polydimethylsiloxane. (google.com)
- The sensor measures your interstitial glucose level, which is the glucose found in the fluid between the cells. (nih.gov)
- The sensor tests glucose every few minutes. (nih.gov)
- A tiny CGM sensor under the skin checks glucose. (nih.gov)
- No source of voltage is required: it's enough simply to immerse the actuator into a solution of glucose in water", says Edwin Jager, senior lecturer in Sensor and Actuator Systems, in the Department of Physics, Chemistry and Biology at Linköping University. (eurekalert.org)
- Increasing number of pipeline studies to develop new glucose sensors is expected to boost the glucose sensor market growth. (marketwatch.com)
- The main aim of this clinical study is to explore the accuracy and acceptability of a non-invasive, wearable glucose sensor in patients living with Diabetes Mellitus. (marketwatch.com)
- Moreover, new product launches for measuring blood glucose levels is also expected to contribute to growth of the glucose sensor market size. (marketwatch.com)
- North America is expected to witness significant growth in the glucose sensor market, owing to presence of major players and launch of new products in this region. (marketwatch.com)
- This sensor continuously measures and monitors glucose levels. (marketwatch.com)
- Furthermore, Asia Pacific glucose sensor market is expected to witness significant growth over the forecast period, owing to increasing diabetes healthcare spending in the region. (marketwatch.com)
- One publication from Dr. Parviz is A contact lens with embedded sensor for monitoring tear glucose level . (healthcentral.com)
- It seems they developed a sensor, mixed some chemicals together (including a glucose solution - the researchers apparently did not use real tears) and measured electrical current. (healthcentral.com)
Monosaccharide4
- Glucose is a simple monosaccharide that is used as an energy source for every cell in the human body. (reference.com)
- Glucose is a common example of a monosaccharide. (reference.com)
- Glucose is the most abundant monosaccharide, a subcategory of carbohydrates. (wikipedia.org)
- Glucose is a monosaccharide containing six carbon atoms and an aldehyde group, and is therefore an aldohexose. (wikipedia.org)
Dextrose1
- Friedrich August Kekulé proposed the term dextrose (from Latin dexter = right), because in aqueous solution of glucose, the plane of linearly polarized light is turned to the right. (wikipedia.org)
Dehydrogenase3
- Not to be confused with Glucose-6-phosphate dehydrogenase . (wikipedia.org)
- and a reaction layer containing at least pyrrolo-quinoline quinone dependent glucose dehydrogenase, formed in contact with or in the vicinity of the electrode system, and the reaction layer contains at least one kind of additive selected from the group consisting of gluconic acid and salts thereof. (google.com)
- 6% w/w FAD glucose dehydrogenase(Aspergillus sp. (walgreens.com)
Type 1 diabet6
- Read on to learn how JDRF research in the past year is making life with type 1 diabetes (T1D) better, including clinical trials of a therapy that helps to reduce HbA1c-which provides a longer-term gauge of blood-glucose control-and improves other key health measures. (jdrf.org)
- Most type 1 diabetes (T1D) patients rely solely on insulin to control their glucose levels, but a growing number of researchers and medical professionals are exploring whether non-insulin drugs could be paired with insulin to better manage T1D. (jdrf.org)
- Improved glycemic control in poorly controlled patients with type 1 diabetes using real-time continuous glucose monitoring. (medscape.com)
- In 1993 the Diabetes Control and Complications Trial showed that keeping blood glucose levels as normal as possible is the best strategy for people with type 1 diabetes to reduce the risks of complications. (mendosa.com)
- Nearly all insurers cover continuous glucose monitors for people with Type 1 diabetes, for whom it's a proven lifesaver. (theepochtimes.com)
- The charity says all people with type-1 diabetes and those with type-2 diabetes who are on glucose-lowering medication, including insulin, need to monitor their blood glucose levels so they can adjust their treatment accordingly. (bbc.co.uk)
Meters10
- Blood glucose meters measure blood glucose levels electronically. (medscape.com)
- There is a recurring cost to using blood glucose meters and disposable strips, but it is outweighed by the costs related to complications of diabetes. (medscape.com)
- Search for test strips that work with the glucose meters that you use at home or with your patients. (staples.com)
- Some blood glucose meters use what is called GDH-PQQ test strips. (wikihow.com)
- writes Connie Kleinbeck, a diabetes educator who compares six talking glucose meters for the National Federation of the Blind. (consumersearch.com)
- Ann Bartlett, a board member of the Juvenile Diabetes Research Foundation who tests talking glucose meters at HealthCentral, adds that the Prodigy Voice can also help people with dyslexia, giving 'both a visual and audio sample to prevent recording the wrong number. (consumersearch.com)
- The Prodigy Voice continues its dominion over other talking glucose meters for very good reason: It's the only model we've seen that can talk you through every single aspect of its use, from setup to calibration, testing and accessing the memory function. (consumersearch.com)
- Basic blood glucose meters have just one job: Sampling a drop of your blood and telling you how high -- or low -- your blood glucose levels are. (consumersearch.com)
- Some basic meters also come with software that lets you track and visualize your blood glucose trends, and a few let you program customizable alerts or flag readings for special circumstances. (consumersearch.com)
- Accuracy and consistency (also called repeatability) should take priority over the fancy bells and whistles you'll find on some modern glucose meters. (consumersearch.com)
Strips9
- Dario Blood Glucose Test Strips for The Dario and Dario LC Blood Glucose Monitoring System. (amazon.com)
- Glucose test strips come in boxes that contain hundreds of test strips. (staples.com)
- Glucose testing strips are easy to use, especially if you follow the included directions. (staples.com)
- It might be better to pay a little more for a glucose monitor if the replacement strips are significantly cheaper than another brand. (vetinfo.com)
- The desiccant keeps the reagent strips dry whileMEASURING THE GLUCOSE the container prevents damage to the reagentCONCENTRATION IN strips by bright light. (slideshare.net)
- Reagent strips such as Haemo-Glukotest specifically with glucose, releasing hydrogen5. (slideshare.net)
- The reagent strips, therefore, are specific for glucose.8-c How to obtain a capillary blood sampleWhile capillary blood is usually used, a sampleof venous or arterial blood is also suitable.Capillary blood is usually obtained from theinfant's heel:1. (slideshare.net)
- Other user-friendly features that make this the top glucometer in our report include its backlit screen and illuminated test strip port, no-coding test strips, great durability, and a 400-reading memory that calculates a number of averages to help you spot trends in your glucose readings. (consumersearch.com)
- Access to blood glucose test strips vital to help diabetics manage their condition is being restricted against government guidance, a charity says. (bbc.co.uk)
Hypoglycemia8
- A low glucose level is called hypoglycemia . (kidshealth.org)
- In aiming for target glucose levels, Dr Zoungas explained that this should be weighed against the risk for hypoglycemia. (medscape.com)
- When you have severe hypoglycemia, it means you can't swallow glucose-containing foods or drinks on your own to bring your levels back up. (diabetes.org)
- With other models, you must first confirm a CGM reading with a finger-stick blood glucose test before you take insulin or treat hypoglycemia . (nih.gov)
- After you check and see that your blood glucose level is low, you should treat hypoglycemia quickly. (archive.org)
- Once you've checked your blood glucose and treated your hypoglycemia, wait 15 or 20 minutes and check your blood again. (archive.org)
- If your blood glucose is still low and your symptoms of hypoglycemia don't go away, repeat the treatment. (archive.org)
- In this product assortment, you'll find a variety of glucose tablets that can be taken to address hypoglycemia. (cvs.com)
Diabetic7
- Comparison of a needle-type and a microdialysis continuous glucose monitor in type 1 diabetic patients. (medscape.com)
- Could someone tell me the glucose values for a non diabetic for the fasting (pre-breakfast), one hour after eating, two hours after eating. (medhelp.org)
- The Economist , "As China puts on weight, type-2 diabetes is soaring," 12 Dec. 2019 In diabetic rats, kimchi improves insulin function and lowers average blood glucose levels. (merriam-webster.com)
- Glucose monitoring is important for any owner with a diabetic cat to ensure they remain healthy and happy. (vetinfo.com)
- sugarBEAT is the first painless, non-invasive continuous glucose monitor (CGM) for use by diabetic and pre-diabetic patients. (marketwatch.com)
- It is the first continuous glucose monitoring system that can be used by diabetic patients to take diabetes treatment decisions without using a blood sample from the fingertip. (marketwatch.com)
- Failure to do so can lead to short-term complications such as diabetic ketoacidosis, which is caused by untreated consistent high blood glucose levels and is potentially fatal, and hypoglycaemia, which is the result of low blood glucose levels. (bbc.co.uk)
Hyperglycemia2
- A high level of glucose is called hyperglycemia . (kidshealth.org)
- Random blood glucose readings can help you identify hyperglycemia and decrease the risk for some chronic complications. (healthline.com)
Higher-than-normal blood glucose levels1
- It refers to higher-than-normal blood glucose levels. (buzzle.com)
Concentration9
- The electrode is designed to allow 'one-point' in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species. (google.co.uk)
- A first glucose concentration-to-current transducing layer is overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited (third layer). (google.co.uk)
- This has been mathematically described by the hyperbolic relationship between AIR and M and referred to as glucose homeostasis, with glucose concentration assumed to remain constant along the hyperbola. (diabetesjournals.org)
- The data point contains fields for the blood glucose concentration, temporal relationships to meals and sleep, and the source of the specimen which was measured. (google.com)
- All fields except for blood glucose concentration are optional. (google.com)
- The blood glucose concentration is measured in mmol/L (1 mmol/L is equivalent to 18 mg/dL). (google.com)
- Measure the glucose concentration of using a reagent strip. (slideshare.net)
- 2. SK ILLS WORKSHOP : GLUCOSE CONTROL AND HYPOGLYCAEMIA 157 higher the concentration of glucose in the blood the greater is the colour change. (slideshare.net)
- Whereas the firing rate of about half the POMC neurons in wild-type mice was stimulated by physiologically relevant increases in glucose concentration, only 1 of 27 POMC neurons in POMC-mut-Kir6.2 mice was glucose-sensitive. (sciencemag.org)
Intolerance12
- What is glucose intolerance? (buzzle.com)
- Symptoms of glucose intolerance include excessive thirst, tiredness, and loss of muscle mass. (buzzle.com)
- When a person has been identified to be glucose intolerant, it is important to follow glucose intolerance diet. (buzzle.com)
- Glucose intolerance is a condition that may lead to the development of diabetes if not taken care of in time. (buzzle.com)
- What does glucose intolerance spell for children? (buzzle.com)
- Treatment options for glucose intolerance are fairly limited, but effective when taken seriously. (buzzle.com)
- ARTIFICIAL sweeteners can cause glucose intolerance in mice, and perhaps in humans, by altering gut bacteria, a series of experiments suggests. (newscientist.com)
- Glucose intolerance occurs when this process becomes inefficient, and is strongly associated with type 2 diabetes. (newscientist.com)
- They showed significant glucose intolerance," says Segal, "at levels comparable to a metabolic disease. (newscientist.com)
- Because what we eat can shift this bacterial make-up , the researchers wondered whether the glucose intolerance might be caused by a change in the bacterial composition. (newscientist.com)
- Wiping out the rodents' gut bacteria using antibiotics abolished all the effects of glucose intolerance in the mice. (newscientist.com)
- The researchers found that the fake stuff drives the kind of glucose intolerance that can lead to diabetes in human. (dictionary.com)
Capillary1
- Another article, Measurement of tear glucose levels with amperometric glucose biosensor/capillary tube configuration, reported that 'A strong correlation between tear and blood glucose levels was found, suggesting that measurement of tear glucose is a potential noninvasive substitute for blood glucose measurements. (healthcentral.com)
Researchers9
- To compare the impact of intensive vs less intensive glucose control on the risk for microvascular events, the researchers conducted an individual-participant-data meta-analysis of randomized controlled trials comparing the two treatment strategies. (medscape.com)
- For some time, researchers have thought about the possible links between how the brain processes glucose and Alzheimer's," said NIA director Richard J. Hodes. (aarp.org)
- After 11 weeks, the researchers tested all the rodents' glucose tolerance by giving them a high-glucose drink and taking regular blood samples. (newscientist.com)
- For example, when the researchers transferred the gut bacteria of mice who had consumed saccharin into mice whose guts were bacteria-free, it caused these previously healthy mice to become glucose intolerant. (newscientist.com)
- So the researchers decided to also give those rodents high doses of glucose . (merriam-webster.com)
- Herbal toothpaste, in particular, can reduce levels of salivary glucose and improve pH levels of saliva, according to researchers from Jawahar Medical Foundation's Annasaheb Chudaman Patil Memorial Dental College (ACPM Dental College). (naturalnews.com)
- Cutting-edge and comprehensive, Glucose Transport: Methods and Protocols is a valuable resource that helps researchers with determining specific roles of different GLUTs in various organisms. (springer.com)
- Researchers from Cardiff University's School of Engineering have developed a glucose monitor that doesn't require you to prick your finger. (engadget.com)
- Researchers at Linköping University have demonstrated that artificial muscles made from polymers can now be powered by energy from glucose and oxygen, just like biological muscles. (eurekalert.org)
Monitor their blood glucose levels1
- Having a talking glucometer makes it possible for those with reduced vision or total blindness -- common side effects of diabetes -- to monitor their blood glucose levels without outside help. (consumersearch.com)
Affecting your blood glucose levels1
- And while optimal health is not about fixating on weight-it's about measuring truly influential parameters like blood glucose, lipid subfractions, and cardiac plaque-nothing will help you lose weight as effectively as understanding how your meals are affecting your blood glucose levels. (amazonaws.com)
Diabetics1
- Diabetics might ultimately have glucose sensors built into their bodies. (technologyreview.com)
Monitoring18
- As such, the global market for blood glucose self-testing products is undergoing a significant transition driven by the advent of new analytical technologies and new recommendations for tight glucose control for monitoring diabetes. (cnbc.com)
- JDRF applauds the FDA decision to approve a new indication for use for the Dexcom G5® Mobile Continuous Glucose Monitoring (CGM) System. (jdrf.org)
- Sleek, compact, and seamless, the One Drop Chrome blood glucose monitoring kit combines advanced diabetes technology with well-designed supplies to match your modern lifestyle. (apple.com)
- Dario Value Pack Kit: Blood Glucose Monitoring Set. (amazon.com)
- FDA expands indication for continuous glucose monitoring system, first to replace fingerstick testing for diabetes treatment decisions. (medscape.com)
- Available at https://www.fda.gov/news-events/press-announcements/fda-expands-indication-continuous-glucose-monitoring-system-first-replace-fingerstick-testing . (medscape.com)
- System accuracy evaluation of 18 CE-marked current-generation blood glucose monitoring systems based on EN ISO 15197:2015. (medscape.com)
- Battelino T, Phillip M. Real-time continuous glucose monitoring in randomized control trials. (medscape.com)
- Mian Z, Hermayer KL, Jenkins A. Continuous Glucose Monitoring: Review of an Innovation in Diabetes Management. (medscape.com)
- A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. (google.co.uk)
- If your cat is on insulin, glucose monitoring at home can help ensure the amounts your cat is receiving are adequate. (vetinfo.com)
- These sensors are connected wirelessly to the continuous glucose monitoring system. (marketwatch.com)
- They offer data to the monitoring system or smart compatible devices that aid to track the level of blood glucose in a patient at regular intervals. (marketwatch.com)
- These insurers say they have seen initial success among members using continuous glucose monitoring (CGM) along with health coaches to help keep their diabetes under control. (theepochtimes.com)
- Self monitoring of blood glucose (SMBG) has been the norm for many years. (diabeteseducator.org)
- Educational courses, including 5.5 hours of free CE focused on glucose monitoring, are also available. (diabeteseducator.org)
- A set of downloadable PDFs for diabetes educators to use with patients to illustrate the importance of blood glucose monitoring, expert recommendations plus tips and tricks for safe, accurate testing. (diabeteseducator.org)
- Create healthcare diagrams like this example called Glucose Monitoring Record Sheet in minutes with SmartDraw. (smartdraw.com)
Enzymes7
- [7] p. 465 This is possible because these enzymes remove two glucose units (i.e. one maltose molecule) at a time from the end of the starch molecule. (wikipedia.org)
- The glucose device consists of electrodes made of compressed graphite discs containing enzymes that catalyze the oxidation of glucose. (technologyreview.com)
- The electrodes sit inside a dialysis bag that keeps enzymes inside but lets glucose and oxygen flow through. (technologyreview.com)
- The device uses enzymes to harvest energy from glucose and oxygen found naturally in the body. (technologyreview.com)
- Glucose and oxygen flowed into the device, but enzymes stayed in place and catalyzed the oxidation of glucose to generate electrical energy. (technologyreview.com)
- 16. The membrane system of claim 9 wherein the enzyme of the enzyme-containing membrane is one or a combination of enzymes which oxidizes glucose and generates hydrogen peroxide. (google.com)
- These enzymes convert glucose and oxygen, in the same way as in the body, to produce the electrons required to power motion in an artificial muscle made from an electroactive polymer. (eurekalert.org)
Molecule4
- discovered (1936) the activated intermediate, glucose 1-phosphate (phosphate bound to a specific carbon atom on the glucose molecule), known as the "Cori ester. (britannica.com)
- In solution, the glucose molecule prefers a ring (cyclic) shape. (ehow.co.uk)
- Six-membered cyclic structures like glucose are called "pyranose," after the hexagonal pyran molecule, which has 5 carbons and an oxygen in its ring just like glucose. (ehow.co.uk)
- The glucose molecule can exist in an open-chain (acyclic) as well as ring (cyclic) form. (wikipedia.org)
Plasma glucose1
- More intensive control also resulted in a difference in mean fasting plasma glucose between the two groups of -1.69 mmol/L. (medscape.com)
Oxygen11
- Corresponding residues in the active site of glucose 6-phosphatase-α include Arg170 and Arg83, which donate hydrogen ions to the phosphate, stabilizing the transition state, His119, which provides a proton to the dephosphorylated oxygen attached to glucose, and His176, which completes a nucleophilic attack on the phosphate to form a covalently bound phosphoryl enzyme intermediate. (wikipedia.org)
- The problem is that for decades, people said Warburg was wrong - mainly because we see a lot of cancer cells take up oxygen and make adenosine triphosphate (ATP) from within the mitochondria … People began to question, 'If cancer cells have normal respiration, why would they want to use glucose as a fermentable fuel? (lewrockwell.com)
- Just as athletes can benefit by eating right and doping their blood to contain more oxygenated cells, the new findings suggest students can improve their performance by eating glucose or breathing pure oxygen. (go.com)
- We found a dose of oxygen or glucose can improve performance on tasks that require great mental effort," says Andrew Scholey, director of the Human Cognitive Neuroscience unit at the University of Northumbria in Newcastle, England. (go.com)
- As mental strain increases, so too does the brain's demand for energy in the form of oxygen and glucose. (go.com)
- He found when the students played the game at beginner levels, doses of oxygen and glucose did not help the their scores. (go.com)
- But as the players reached more challenging levels, the students showed significant improvement after sucking oxygen and drinking a sweet, lemon-flavored glucose drink. (go.com)
- We hope to understand how interventions like gingko can improve oxygen and glucose in the blood and help deliver more to the brain over a longer period," he said. (go.com)
- Jobs envisioned wearable devices, like smartwatches, being used to monitor important vitals, such as oxygen levels, heart rate and blood glucose. (cnbc.com)
- The motion of our muscles is powered by energy that is released when glucose and oxygen take part in biochemical reactions. (eurekalert.org)
- They have now demonstrated the principle using artificial muscles powered by the same glucose and oxygen as our bodies use. (eurekalert.org)
Glycogen3
- Glucose molecules can also be linked into chains to form the polysaccharides cellulose, glycogen, and starch. (dictionary.com)
- Many complex carbohydrates (starch, glycogen, cellulose) are polymers (long chains) of the glucose ring, repeating over and over. (ehow.co.uk)
- In animals, glucose is released from the breakdown of glycogen in a process known as glycogenolysis. (wikipedia.org)
Postprandial glucose2
- We simply can't know how unfavorable our postprandial glucose levels are unless we check. (amazonaws.com)
- We provide evidence from cross-sectional, longitudinal, and prospective data from Pima Indians ( n = 413) and Caucasians ( n = 60) that fasting and postprandial glucose concentrations increase with decreasing M despite normal compensation of AIR. (diabetesjournals.org)
Carbohydrate6
- You can also correct a high blood glucose level by typing into the insulin pump your blood glucose or grams of carbohydrate to be eaten. (umassmed.edu)
- The Glucose Revolution is about the glycemic index, a scientifically validated tool that can help you find the right kind of carbohydrate to control hunger, improve athletic performance, and most especially to manage diabetes. (mendosa.com)
- Carbohydrate has the most immediate effect on blood glucose. (mendosa.com)
- The Glucose Revolution includes a table of some 300 different foods listing their glycemic indexes and the carbohydrate and fat content in a sample serving. (mendosa.com)
- Is Glucose a Carbohydrate? (reference.com)
- Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight, where it is used to make cellulose in cell walls, which is the most abundant carbohydrate. (wikipedia.org)
Urine11
- Sweet smelling -remember the renal threshold - some people naturally excrete glucose in their urine. (amazonaws.com)
- The power remained around two microwatts for 11 days in one rat, and the other rat showed byproducts of glucose oxidation in its urine for three months, indicating that the device lasts at least that long. (technologyreview.com)
- The presence of glucose in the urine is called glycosuria or glucosuria. (ucsfhealth.org)
- The color the dipstick changes to tells the provider the level of glucose in your urine. (ucsfhealth.org)
- Now, blood tests to measure glucose level in the blood are easy to do and are used instead of the glucose urine test. (ucsfhealth.org)
- The glucose urine test may be ordered when the doctor suspects renal glycosuria. (ucsfhealth.org)
- This is a rare condition in which glucose is released from the kidneys into the urine, even when the blood glucose level is normal. (ucsfhealth.org)
- Glucose is not usually found in urine. (ucsfhealth.org)
- Small increases in urine glucose levels after a large meal are not always a cause for concern. (ucsfhealth.org)
- Pregnancy: Up to half of women have glucose in their urine at some time during pregnancy. (ucsfhealth.org)
- Glucose in the urine may mean that a woman has gestational diabetes . (ucsfhealth.org)
Readings3
- So I started taking supplements for Blood pressure and to help glucose and I kept notes about my readings in apple notes on my iPhone. (apple.com)
- Glucose Readings Normal? (medhelp.org)
- The monitor constantly tracks glucose levels, sends readings to a patient's cellphone and doctor, and alerts patients when readings are headed too high or too low. (theepochtimes.com)
Uptake2
- Impaired myocardial energetics in cardiac hypertrophy also triggers AMP-activated protein kinase (AMPK), leading to increased glucose uptake and glycolysis. (nih.gov)
- I cannot solve your problem i.e. giving you an answer why this happens, but I have some thoughts: 1a) the oil could delay the glucose uptake in the digestive system - do you feed oil to the controls, too? (bio.net)
Monitors7
- How do blood glucose monitors work? (medscape.com)
- Ramljak S, Musholt PB, Schipper C, Flacke F, Sieber J, Borchert M. The precision study: examining the inter- and intra-assay variability of replicate measurements of BGStar, iBGStar and 12 other blood glucose monitors. (medscape.com)
- Lane JE, Shivers JP, Zisser H. Continuous glucose monitors: current status and future developments. (medscape.com)
- It's no wonder that it beat four other talking glucose monitors in a study published in the Journal of Diabetes Science and Technology, and has won awards from the National Federation of the Blind and American Foundation for the Blind. (consumersearch.com)
- But continuous glucose monitors aren't cost-effective for Type 2 diabetes patients who don't use insulin, said Dr. Silvio Inzucchi, director of the Yale Diabetes Center. (theepochtimes.com)
- Neither finger-prick tests nor glucose monitors look at A1c. (theepochtimes.com)
- The continuous glucose monitors also don't assess blood glucose. (theepochtimes.com)
Level22
- at a given moisture level and temperature, a maltose solution has a lower viscosity than a glucose solution, but will still set to a hard product. (wikipedia.org)
- You can see your glucose level anytime at a glance. (nih.gov)
- An alarm can sound when your glucose level goes too low or too high. (nih.gov)
- A graphic on the CGM screen shows whether your glucose is rising or dropping-and how quickly-so you can choose the best way to reach your target glucose level. (nih.gov)
- The blood-glucose levels of the mice consuming the sweeteners spiked at a higher level than all the control groups and also took longer to drop back down to normal. (newscientist.com)
- Check blood glucose levels to determine when your level is low. (archive.org)
- You should check your blood glucose level according to the schedule you work out with your doctor. (archive.org)
- After you feel better, be sure to eat your regular meals and snacks as planned to keep your blood glucose level up. (archive.org)
- The user can view what their glucose level has been, what it is at that moment, and which way it's heading. (umassmed.edu)
- A specially coated strip containing a fresh sample of blood is inserted in a machine, when then calculates the correct level of glucose in the blood sample and shows the result in a digital display. (everything2.com)
- The glucose tolerance test identifies abnormalities in the way your body handles glucose after a meal - often before your fasting blood glucose level becomes abnormal. (mayoclinic.org)
- This blood sample will be used to measure your fasting blood glucose level. (mayoclinic.org)
- Your blood glucose level will be tested again one, two and three hours after you drink the solution. (mayoclinic.org)
- After drinking the glucose solution, you'll likely need to remain in the doctor's office or lab while you're waiting for your blood glucose level to be tested. (mayoclinic.org)
- A normal blood glucose level is lower than 140 mg/dL (7.8 mmol/L). (mayoclinic.org)
- A blood glucose level of 200 mg/dL (11.1 mmol/L) or higher may indicate diabetes. (mayoclinic.org)
- A 5% to 10% change in weight can help immensely in controlling blood glucose level. (selfgrowth.com)
- Treatment of other associated conditions such as high blood pressure and high cholesterol also help in maintaining normal blood glucose level. (selfgrowth.com)
- Certain foods are very good at helping you keep your blood glucose at about the right level. (diabetes.org.uk)
- Glucose level can also be measured using a blood test or a cerebrospinal fluid test . (ucsfhealth.org)
- The treatment of diabetes relies on controlling your blood glucose level. (healthline.com)
- A review article in 2011, Noninvasive Diagnostic Devices for Diabetes through Measuring Tear Glucose , said that contact lenses 'are being considered by at least three research groups who are working with such sensors as an alternative tool to continuously and noninvasively monitor the level of glucose in tears. (healthcentral.com)
Increases1
- We therefore hypothesized that despite appropriate β-cell compensation (reflected by a constant DI), glucose increases when M decreases. (diabetesjournals.org)
Naturally4
- But while today's insulin formulations save lives, it's difficult to achieve the tight control over blood glucose that occurs naturally in people without diabetes. (jdrf.org)
- Glucose occurs naturally in the sap of most plants but is found in significant amounts in many grains, fruits and vegetables. (ehow.com)
- The naturally occurring form of glucose is d-glucose, while l-glucose is produced synthetically in comparatively small amounts and is of lesser importance. (wikipedia.org)
- Glucose is naturally occurring and is found in fruits and other parts of plants in its free state. (wikipedia.org)
Meals3
- How your glucose changes at different meals? (apple.com)
- You can note your meals, physical activity, and medicines in a CGM device, too, alongside your glucose levels. (nih.gov)
- Testing after meals measures glucose levels around two hours after the start of a meal. (healthline.com)
Brain breaks down glucose1
- For the first time, scientists have found a connection between abnormalities in how the brain breaks down glucose and the severity of the signature amyloid plaques and tangles in the brain, as well as the onset of eventual outward symptoms, of Alzheimer's disease," according to a news release from the National Institutes of Health's Institute on Aging (NIA. (aarp.org)
Body's3
- The condition is diagnosed with the help of a glucose tolerance test, which measures the body's response to glucose. (buzzle.com)
- Studies done in the 1970s showed that glucose can improve brain performance, particularly if a subject is feeling depressed or angry or distracted, by increasing the organ's ability to make more of the body's mood regulator, serotonin. (go.com)
- Diabetes is a disease that affects your body's ability to release insulin from your pancreas once sugars are turned into glucose. (healthline.com)
High glucose levels2
- Diabetes is one thing that can cause high glucose levels. (kidshealth.org)
- A group of scientists has recently discovered a link between high glucose levels in the brain and symptoms of memory loss, which could lead to Alzheimer's. (naturalnews.com)
Production of glucose1
- Maltose is also less humectant than glucose, so candy produced with high-maltose syrup will not become sticky as easily as candy produced with a standard glucose syrup.p. 81 Irrespective of the feedstock or the method used for hydrolysis, certain steps are common to the production of glucose syrup: Before conversion of starch to glucose can begin, the starch must be separated from the plant material. (wikipedia.org)
Https1
- Merriam-Webster.com Dictionary , Merriam-Webster, https://www.merriam-webster.com/dictionary/glucose. (merriam-webster.com)
Replace fingerstick1
- The Dexcom G5® CGM is now indicated to replace fingerstick blood glucose testing for diabetes management decisions. (jdrf.org)
Starch7
- Glucose syrup , also known as confectioner's glucose , is a syrup made from the hydrolysis of starch . (wikipedia.org)
- Maize (corn) is commonly used as the source of the starch in the US, in which case the syrup is called " corn syrup ", but glucose syrup is also made from potatoes and wheat , and less often from barley , rice and cassava . (wikipedia.org)
- Depending on the method used to hydrolyse the starch and on the extent to which the hydrolysis reaction has been allowed to proceed, different grades of glucose syrup are produced, which have different characteristics and uses. (wikipedia.org)
- The original glucose syrups were manufactured by acid hydrolysis of corn starch at high temperature and pressure. (wikipedia.org)
- Before conversion of starch to glucose can begin, the starch must be separated from the plant material. (wikipedia.org)
- Formerly, glucose syrup was only produced by combining corn starch with dilute hydrochloric acid , and then heating the mixture under pressure. (wikipedia.org)
- Currently, glucose syrup is mainly produced by first adding the enzyme α-amylase to a mixture of corn starch and water. (wikipedia.org)
Mmol1
- Results of the oral glucose tolerance test are given in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). (mayoclinic.org)
Syrup14
- Glucose syrup containing over 90% glucose is used in industrial fermentation , [3] but syrups used in confectionery contain varying amounts of glucose , maltose and higher oligosaccharides , depending on the grade, and can typically contain 10% to 43% glucose. (wikipedia.org)
- [4] Glucose syrup is used in foods to sweeten, soften texture and add volume. (wikipedia.org)
- By converting some of the glucose in corn syrup into fructose (using an enzymatic process), a sweeter product, high fructose corn syrup can be produced. (wikipedia.org)
- [6] A typical confectioner's syrup contains 19% glucose, 14% maltose, 11% maltotriose and 56% higher molecular mass carbohydrates . (wikipedia.org)
- By using β-amylase or fungal α-amylase , glucose syrups containing over 50% maltose, or even over 70% maltose (extra-high-maltose syrup) can be produced. (wikipedia.org)
- Maltose is also less humectant than glucose, so candy produced with high-maltose syrup will not become sticky as easily as candy produced with a standard glucose syrup. (wikipedia.org)
- Glucose syrup can be produced by acid hydrolysis , enzyme hydrolysis, or a combination of the two. (wikipedia.org)
- In the United States the main source of glucose used in food production is corn, which is converted into corn syrup and high-fructose corn syrup. (ehow.com)
- Around the world, wheat, barley, rice, maize and other starches are the main sources used to produce glucose syrup. (ehow.com)
- Glucose syrup is added to most processed tomato goods because it gives a sweeter taste and balances the natural acidity of tomatoes. (ehow.com)
- Glucose syrup is widely used both for its sweet taste and because it does not crystallize easily, improving the texture of confectionery items like candy and frosting. (ehow.com)
- Many foods that are considered to be savory tasting are often processed with the use of glucose syrup. (ehow.com)
- Glucose syrup is added to the glue on envelopes and the back of stamps to improve their taste. (ehow.com)
- Glucose syrup was first made in 1811 in Russia by Gottlieb Kirchhoff using heat and sulfuric acid. (wikipedia.org)
Form of glucose1
- In plant cells, chloroplasts perform photosynthesis, a process that converts light energy from the sun into chemical energy in the form of glucose. (reference.com)
Structure of glucose2
- Due to its tight association to the ER, the exact structure of glucose 6-phosphatase remains unknown. (wikipedia.org)
- Cyclic structure of glucose" last modified May 13, 2017. (ehow.co.uk)
Normal5
- The SGLT1 protein in kidney cells plays a role in maintaining normal blood glucose levels. (medlineplus.gov)
- Under normal conditions, the blood tests should show an initial spike in glucose, followed by a decline as the body secretes the insulin in response. (newscientist.com)
- A fasting glucose reading of less than 100 mg/dL is normal. (healthline.com)
- Random glucose testing isn't a substitute for your normal glucose testing schedule. (healthline.com)
- Although the body weight of POMC-mut-Kir6.2 mice was normal, glucose homeostasis was impaired so that they showed an exaggerated increase in blood glucose after intraperitoneal glucose injection. (sciencemag.org)
Complications5
- Intensive glucose lowering in patients with type 2 diabetes significantly reduces the risk for microvascular kidney and eye complications over the longer term, according to the results of an individual-participant-data meta-analysis. (medscape.com)
- These data just reinforce the importance of glucose control for the prevention of microvascular complications," alongside blood-pressure lowering, lipid management, and diet and exercise. (medscape.com)
- Long-term increased blood glucose levels can eventually cause dangerous complications. (healthline.com)
- Testing your blood glucose levels at various times throughout the day can help you manage your diabetes and reduce your risk of diabetes complications . (healthline.com)
- In the long term, high blood glucose levels can lead to serious complications such as blindness, strokes and the need for amputations. (bbc.co.uk)