The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures.
Sensation of making physical contact with objects, animate or inanimate. Tactile stimuli are detected by MECHANORECEPTORS in the skin and mucous membranes.
Modified epidermal cells located in the stratum basale. They are found mostly in areas where sensory perception is acute, such as the fingertips. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber. Do not confuse with Merkel's corpuscle which is a combination of a neuron and an epidermal cell.
A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.
Act of eliciting a response from a person or organism through physical contact.
The functions of the skin in the human and animal body. It includes the pigmentation of the skin.
Carnivores of the genus Procyon of the family PROCYONIDAE. Two subgenera and seven species are currently recognized. They range from southern Canada to Panama and are found in several of the Caribbean Islands.
Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.
The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.
A continuing periodic change in displacement with respect to a fixed reference. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Four or five slender jointed digits in humans and primates, attached to each HAND.
Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.
The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
The minimum amount of stimulus energy necessary to elicit a sensory response.
Amount of stimulation required before the sensation of pain is experienced.
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.
The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
Tumors or cancer of the SKIN.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.
Uptake of substances through the SKIN.
Coloration of the skin.
Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.
Skin diseases caused by bacteria.
The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).
Congenital structural abnormalities of the skin.
Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS.
Any inflammation of the skin.
Operative procedures performed on the SKIN.
Skin diseases caused by viruses.
A water-soluble medicinal preparation applied to the skin.
Biological activities and functions of the SKIN.
Mutant strains of mice that produce little or no hair.
A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)
That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants.
A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.
Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of causes.
The application of suitable drug dosage forms to the skin for either local or systemic effects.
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites.
A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
Any horny growth such as a wart or callus.
Restoration of integrity to traumatized tissue.
Irradiation directly from the sun.
Chemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation.
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.
Mutant strains of rats that produce little or no hair. Several different homozygous recessive mutations can cause hairlessness in rats including rnu/rnu (Rowett nude), fz/fz (fuzzy), shn/shn (shorn), and nznu/nznu (New Zealand nude). Note that while NUDE RATS are often hairless, they are most characteristically athymic.
7,12-Dimethylbenzanthracene. Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.
Visible accumulations of fluid within or beneath the epidermis.
An injury to the skin causing erythema, tenderness, and sometimes blistering and resulting from excessive exposure to the sun. The reaction is produced by the ultraviolet radiation in sunlight.
Small, sacculated organs found within the DERMIS. Each gland has a single duct that emerges from a cluster of oval alveoli. Each alveolus consists of a transparent BASEMENT MEMBRANE enclosing epithelial cells. The ducts from most sebaceous glands open into a HAIR FOLLICLE, but some open on the general surface of the SKIN. Sebaceous glands secrete SEBUM.
Dermatologic disorders attendant upon non-dermatologic disease or injury.
Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.
A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.
Loss of water by diffusion through the skin and by evaporation from the respiratory tract.
Oleagenous substances used topically to soothe, soften or protect skin or mucous membranes. They are used also as vehicles for other dermatologic agents.
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.
Drugs used to treat or prevent skin disorders or for the routine care of skin.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
They had cutaneous lesions on the glabrous skin or the scalp. These localized lesions are frequently accompanied by itching. ... It obtains nutrients from keratin-rich skin, nails and hair, releasing enzymes during its digestion that elicit a host immune ... In rare cases, immunocompromised individuals form severe dissemination on the skin, instead of small localized lesions as a ... Microsporum gallinae has been isolated from the scalp, and smooth skin in human populations. Microsporum gallinae infections ...
In glabrous (hairless) skin, there are four principal types of mechanoreceptors, each shaped according to its function. The ... There are four main types of mechanoreceptors in glabrous, or hairless, mammalian skin: lamellar corpuscles (Pacinian ... The Slowly Adapting type 2 (SA2) mechanoreceptors, with the Ruffini corpuscle end-organ, respond to skin stretch, but have not ... They are located in the skin, like other cutaneous receptors. They are all innervated by Aβ fibers, except the mechanorecepting ...
C-LTMRs also seem to exist in the rat glabrous skin (see [5]). This author provided direct electrophysiological existence of a ... In animals, they have been found electrophysiologically in the glabrous skin of the rat hindpaw, supporting the evidence of ... Nagi, Saad S.; Mahns, David A. (2013-08-18). "Mechanical allodynia in human glabrous skin mediated by low-threshold cutaneous ... neurons in glabrous skin of the rat hindpaw". Neuroscience Letters. 613: 25-29. doi:10.1016/j.neulet.2015.12.040. ISSN 1872- ...
"Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin". Neurosci. Lett. 197 (1): 25-8. ... Small unmyelinated sensory nerve terminals in the skin also express NMDA and non-NMDA receptors. Subcutaneous injections of ... raising possibilities of targeting peripheral glutamate receptors in the skin for pain treatment. Specific medical conditions ... receptor blockers in rats successfully analgesized skin from formalin-induced inflammation, ...
Mechanoreceptors are situated in highly vascularized skin, and appear in both glabrous and hairy skin. Each mechanoreceptor is ... Skin used by the single receptor ending of a temperature-sensitive nerve fiber is small. There are 20 cold points per square ... This may be due to callouses forming on the skin of the most used hand, creating a buffer between the stimulus and the receptor ... Then specific cutaneous cold and warm receptors conduct units that exhibit a discharge at constant skin temperature. Warm and ...
The glabrous skin of the human hand has a paramount role in discriminative touch. Thus the tactile organization of this skin ... It has been found that the percept elicited from a single tactile afferent in the glabrous skin of the hand, may be remarkably ... It has been shown that tactile afferents from the glabrous skin of the hand exert profound effects on hand and finger muscles ... It has been shown that tactile sense organs in the glabrous skin are involved in timely linking the separated phases to a ...
This species has a propensity to infect glabrous (hairless) skin and is only exceptionally known from other sites. Transmission ... A skin test is ineffective in diagnosing active infection and often yields false negative results. Trichophyton rubrum is ... It is an exclusively clonal, anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common ... As a preliminary test indicating infection, plucked hairs and skin and nail scrapings can be directly viewed under a microscope ...
Lindblom, U (1974). "Touch perception threshold in human glabrous skin in terms of displacement amplitude on stimulation with ...
Others serve to anchor the epidermis glabrous skin (hairless), and hyper-proliferative epidermis (from a skin disease). They ... Epidermis and dermis of human skin Section of epidermis List of keratins expressed in the human integumentary system McGrath, J ... p. 1. ISBN 978-0-7234-3541-9. "Skin Cancer (Non-Melanoma) - Introduction". Cancer.Net. 25 June 2012. "Basal Cell Carcinoma - ... account for around 80 per cent of all skin cancers. Not all basal-cell cancers originate in the basal cells but they are so ...
More specifically, they are primarily located in glabrous skin just beneath the epidermis within the dermal papillae. Feelings ... This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to light touch. In particular, they ... They are distributed on various areas of the skin, but concentrated in areas especially sensitive to light touch, such as the ... The number of tactile corpuscles per square millimeter of human skin on the fingertips drops fourfold[clarification needed] ...
The leaf is also acute with a accuminate apex and a rounded base, and a glabrous or nearly glabrous skin. Guijo is generally ...
... are one of the four major types of mechanoreceptor cell in glabrous (hairless) mammalian skin. They are nerve endings in the ... Pacinian corpuscles respond when the skin is rapidly indented but not when the pressure is steady, due to the layers of ... Action potentials are formed when the skin is rapidly distorted but not when pressure is continuous because of the mechanical ... Pacinian corpuscles are rapidly adapting (phasic) receptors that detect gross pressure changes and vibrations in the skin. Any ...
... especially on glabrous skin; however, it may occur on any part of the body. It is similar to other forms of tinea. It may have ... avoid skin to skin contact with infected persons and animals, wear clothing that allows the skin to breathe, and don't share ... Sometimes the skin surrounding the rash may be dry and flaky. Almost invariably, there will be hair loss in areas of the ... If the skin scrapings are negative and a fungus is still suspected, the scrapings are sent for culture. Because the fungus ...
In varying degrees most mammals have some skin areas without natural hair. On the human body, glabrous skin is found on the ... The human body, apart from areas of glabrous skin, is covered in follicles which produce thick terminal and fine vellus hair. ... Hair grows everywhere on the external body except for mucus membranes and glabrous skin, such as that found on the palms of the ... Dark skin probably evolved after humans lost their body fur, because the naked skin was vulnerable to the strong UV radiation ...
... or skin. With the exception of areas of glabrous skin, the human body is covered in follicles which produce thick terminal and ...
... airway epithelia and in hairless or glabrous skin. NLRP1 polymorphisms are associated with skin extra-intestinal manifestations ... Its highest expression was detected in human skin, in psoriasis and in vitiligo. Polymorphisms of NLRP1 were found in lupus ... September 2016). "Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome ...
This species has a propensity to infect glabrous (hairless) skin and is only exceptionally known from other sites.[12] ... It is an exclusively clonal,[1] anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common ... As a preliminary test indicating infection, plucked hairs and skin and nail scrapings can be directly viewed under a microscope ... a clinical guide and laboratory handbook of dermatophytes and other filamentous fungi from skin, hair, and nails. Belmont, CA: ...
... especially on glabrous skin; however, it may occur on any part of the body, it present as annular, marginated plaque with thin ... Tinea or ringworm is any of a variety of skin mycoses. Tinea is a very common fungal infection of the skin. Tinea is often ... The skin may peel while it is being treated. Tinea faciei is contagious just by touch and can spread easily to all regions of ... Fungi are more difficult to kill inside and underneath a nail than on and in the skin. But if the nail infection is not cured, ...
... or any body part except glabrous (hairless) skin (like the palms or soles of feet). Often the lesions can appear on the face, ... Yosipovitch G, DeVore A, Dawn A (June 2007). "Obesity and the skin: skin physiology and skin manifestations of obesity". ... They are skin-colored bumps the size of a grain of sand, many of which are surrounded by a slight pink color in light-skinned ... KP is commonly described in association with other dry-skin conditions, such as ichthyosis vulgaris, dry skin, and atopic ...
... hairy and glabrous skin (hairless).[4] The adjective cutaneous literally means "of the skin" (from Latin cutis, skin). ... Skin color[edit]. Main article: Human skin color. Human skin shows high skin color variety from the darkest brown to the ... Diseases of the skin include skin infections and skin neoplasms (including skin cancer). ... Skin repair. References[edit]. *^ a b c d e f "Skin care" (analysis), Health-Cares.net, 2007, webpage: HCcare Archived 12 ...
The glabrous skin on the sole of the foot lacks the hair and pigmentation found elsewhere on the body, and it has a high ... Likewise, the sural nerve provides sensory innervation to the skin on the lateral side of the foot as well as the skin on the ... The sole contains the thickest layers of skin on the body due to the weight that is continually placed on it. It is crossed by ... The tibial nerve from the sciatic nerve provides sensory innervation to the skin of the sole and toes, and the dorsal aspect of ...
மயிரற்ற தோல் (glabrous skin) பகுதிகளைத் தவிர்த்து, மனிதர்களின் தோல்பகுதி முழுவதும் தடித்த இறுதியான மற்றும் நயமான இளமயிர்களை ...
Density and structural variations of Meissner's corpuscle at different sites in human glabrous skin. J Anat Soc India. 2008;57( ... The mucocutaneous end-organ: the primary organized sensory ending in human skin. AMA Arch Dermatol. 1957;76(2):225-35. PMID ...
In mammals, Merkel nerve endings have a wide distribution and are found in the basal layer of glabrous and hairy skin, in hair ... If the skin is touched in two separate points within a single receptive field, the person will be unable to feel the two ... In hairy skin, Merkel nerve endings are clustered into specialized epithelial structures called "touch domes" or "hair disks". ... They fire fastest, when small points indent the skin, and fire at a low rate on slow curves or flat surfaces. Convexities ...
By other methods, including those resulting from his inventing high-resolution stimulation of the glabrous skin by lateral ... Later, he replicated this phenomenon using several methods, for example by anaesthetic removal of skin sensations, in order to ... Effect Of Skin Hydration On The Dynamics Of Fingertip Gripping Contact », Journal of the Royal Society Interface, 2011, 8(64), ... Spatio-Temporal Skin Strain Distribu- tions Evoke Low Variability Spike Responses In Cuneate Neurons », Journal of the Royal ...
The glabrous (hairless) skin on the front of the hand, the palm, is relatively thick and can be bent along the hand's flexure ... In contrast, the hairy skin on the dorsal side is thin, soft, and pliable, so that the skin can recoil when the fingers are ... are known as skin folds (interdigital folds or plica interdigitalis). They are defined as "one of the folds of skin, or ... The skin in this area contains dermal papillae to increase friction, such as are also present on the fingers and used for ...
... is a distinctively shaped callus of dead skin that usually occurs on thin or glabrous (hairless and smooth) skin surfaces, ... They can sometimes occur on the thicker skin of the palms or bottom of the feet. Corns form when the pressure point against the ... To exclude other differential diagnoses, a skin biopsy may be taken. Imaging studies can be used in order to detect any ... Hard corns are especially problematic for people with insensitive skin due to damaged nerves (e.g., in people with diabetes ...
... tinea of glabrous skin", „onychomycosis", „vulvovaginal candidosis", „cutaneous candidosis", "oral candidosis", and "tinea ...
In late autumn, chemicals on the skin of the caterpillar interact with the fungal spores and release the fungal mycelia, which ... glabrous, and longitudinally furrowed or ridged. ... are most vulnerable to the fungus after shedding their skin, ...
It is used in popular medicine as remedy for skin diseases. Etymology[edit]. It is the fusion of the names of the genera Myrcia ... The leaves are 2.2-8 cm long and 1.3 cm wide, glossy green and glabrous above and pale green and hairy below when young. ...
Dandelion pollen may cause allergic reactions when eaten, or adverse skin reactions in sensitive individuals. Contact ... However, the leaves of dandelions are smooth or glabrous, whereas those of catsears are coarsely hairy. ...
The glabrous skin on the sole of the foot lacks the hair and pigmentation found elsewhere on the body, and it has a high ... Likewise, the sural nerve provides sensory innervation to the skin on the lateral side of the foot as well as the skin on the ... The sole contains the thickest layers of skin on the body due to the weight that is continually placed on it. It is crossed by ... The superficial and deep branches of the lateral plantar nerve from the tibial nerve provide sensory innervation to the skin of ...
... whereas others serve to anchor the epidermis glabrous skin (hairless), and hyper-proliferative epidermis (from a skin disease). ... the outer covering of skin in mammals. ...
The two main types of human skin are glabrous skin, the nonhairy skin on the palms and soles (also referred to as the " ... Diseases of the skin include skin infections and skin neoplasms (including skin cancer).[28] ... Layer of skin involved[edit]. Main article: Integumentary system. The skin weighs an average of 4 kg (8.8 lb), covers an area ... Main article: Epidermis (skin). The epidermis is the most superficial layer of skin, a squamous epithelium with several strata ...
... s are also found in hairless areas (glabrous skin) of the eyelids, nose, penis, labia minora, the inner mucosal ... Sebaceous glands are involved in skin problems such as acne and keratosis pilaris. In the skin pores, sebum and keratin can ... "Thematic Review Series: Skin Lipids. Antimicrobial lipids at the skin surface". 10 May 2011.. ... slightly acidic film on the surface of the skin that acts as a barrier to microbes that might penetrate the skin.[19] The pH of ...
... is a specially shaped callus of dead skin that usually occurs on thin or glabrous (hairless and smooth) skin surfaces, ... They can sometimes occur on the thicker palmar or plantar skin surfaces. Corns form when the pressure point against the skin ... Because diabetes affects the capillaries, the small blood vessels which feed the skin, thickening of the skin with callus ... It is the natural reaction of the palmar or plantar skin. Too much friction occurring too fast for the skin to develop a ...
The fruit (legume) of the tree is a woody, glabrous and deep purple Pod. Each Pod contains around 3 - 9 round shaped seeds. The ... Compresses with young leaves can be used for curing skin problems, whereas burnt old leaves are believed to relieve itchy ...
Leaves are glabrous and sometimes pubescent beneath. Leaf stalks are very short. The flowers appear (in India) from March to ... According to Ayurveda, the bark is useful in treatment of diarrhoea, piles, ringworm and other skin diseases. Seeds also have ...
The shoots are orange-brown and glabrous (hairless). The leaves are needle-like with blunt tips,[7] 12-24 mm (15⁄32-15⁄16 in) ... skin, locomotor system, gastrointestinal tract and infections.[26] ...
Leaves are small, 1-6 cm (0.39-2.36 in) long and 3-25 mm (0.12-0.98 in) wide, glabrous, with a notched tip and crenate towards ... Green skin type finger lime Scientific classification Kingdom:. Plantae Clade:. Angiosperms Clade:. Eudicots ...
Within entomology, the term glabrous is used to refer to those parts of an insect's body lacking in setae (bristles) or scales ... In arthropods, the integument, the external "skin", or "shell", is the product of a single layer of ectodermal epithelium. That ...
All parts of the plant are hairless (glabrous); the leaves are two- to four-pinnate, finely divided and lacy, overall ... While hemlock toxicity primarily results from consumption, poisoning can also result from inhalation, and from skin contact.[ ...
Burra is used as a topical medication, the liquid derived from a preparation of the leaves is used for skin complaints. It is ... sepals and flower stalks are glabrous and thickly covered with resin making them very sticky and shiny. The leaves vary in size ...
Stem is pubescent while the primary leaflets are glabrous on top and slightly pubescent on the underside. Compound leaves are ... This includes: increasing red blood cell count, gastrointestinal aid, topical treatment for certain skin issues like pox, and ...
The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the " ... Peeling skin syndrome (acral peeling skin syndrome, continual peeling skin syndrome, familial continual skin peeling, ... primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, trabecular carcinoma of the skin) ... Skin Disorders at Curlie All the Internet - Directory - Main/Health/Conditions_and_Diseases/Skin_Disorders Images in Clinical ...
Flowering occurs from October to January and the fruit is a glabrous capsule 2.5-3 mm (0.1-0.1 in) long and 1.5-2 mm (0.06-0.08 ... "garment worn next to the skin", referring to the leaves which are only hairy near the base. The Mt Arthur boronia grows in the ...
Leaves are simple, the adult leaves are glabrous, though occasionally with a few hairs on the nerves. The gynophore is shorter ... Aw krâpë (av kraboe, ao krâpoeu) (aw="skin", krâpë="crocodile", Khmer) is a name used in Cambodia. The wood furnishes firewood ... than 5mm and hairy, the ovary is glabrous. Flowering occurs from November to March, fruiting from January to April. This ...
by Pakistan Armed Forces Medical Journal; Health, general Hand Injuries Hand injuries Political corruption Skin ... GLABROUS SKIN GRAFT FOR PALMER SKIN DEFECTS; SIMPLE BUT USEFUL PROCEDURE. ... glabrous skin should be replaced with glabrous skin. Palm and sole remain the exclusive source of glabrous skin.. Recent ... Glabrous and non glabrous skin is different histologically. Glabrous skin has thicker epidermal layer with well defined stratum ...
2. One hundred and one slowly adapting receptors with receptive fields in the glabrous skin area were studied. The units were ... Stimulus-response functions of slowly adapting mechanoreceptors in the human glabrous skin area J Physiol. 1975 Feb;245(1):63- ... 2. One hundred and one slowly adapting receptors with receptive fields in the glabrous skin area were studied. The units were ... 5. The neural response to stimuli of varying skin indentation amplitudes was analyzed. The threshold for a dynamic response ...
The impulse responses to perpendicular sinusoidal skin displacements were recorded from 4 different types of mechanoreceptive ... different units innervating the glabrous skin of the human hand. The cycle responses, defined as the number of impulses evoked ... Responses of mechanoreceptive afferent units in the glabrous skin of the human hand to sinusoidal skin displacements Brain Res ... skin displacements were recorded from 4 different types of mechanoreceptive different units innervating the glabrous skin of ...
K. S. Frahmet al., "Spatial temperature distribution in human hairy and glabrous skin after infrared CO. 2. laser radiation," ... Temporal and spatial temperature distribution in the glabrous skin of rats induced by short-pulse CO2 laser. ... "Temporal and spatial temperature distribution in the glabrous skin of rats induced by short-pulse CO2 laser," Journal of ... "Temporal and spatial temperature distribution in the glabrous skin of rats induced by short-pulse CO2 laser," J. Biomed. Opt. ...
... ... We show here that onset of PPK is preceded by oxidative stress in male Krt16-/- mouse footpad skin, correlating with an ... Preliminary data suggests that dual treatment of footpad skin with SF and selective estrogen receptor β agonist ... footpad skin. Topical application of the small-molecule Nrf2 activator sulforaphane (SF) in male Krt16-/- mice prevents the ...
Functional properties of primary afferent units probably related to pain mechanisms in primate glabrous skin. / Georgopoulos, A ... Functional properties of primary afferent units probably related to pain mechanisms in primate glabrous skin. Journal of ... title = "Functional properties of primary afferent units probably related to pain mechanisms in primate glabrous skin", ... T1 - Functional properties of primary afferent units probably related to pain mechanisms in primate glabrous skin ...
... on WN Network delivers the latest Videos and Editable pages for News & Events, including Entertainment, Music, Sports ... Glabrous skin. In varying degrees most mammals have some skin areas without natural hair. On the human body, glabrous skin is ... Glabrous features may be an important means of identifying flora species. Glabrous characteristics of leaves, stems, and fruit ... In botany and mycology, a glabrous morphological feature is smooth, glossy, having no trichomes (bristles or hair-like ...
... get under skin explanation free. What is get under skin? Meaning of get under skin medical term. What does get under skin mean? ... Looking for online definition of get under skin in the Medical Dictionary? ... Skin may be classified as thin and hairy or thick and hairless (glabrous). Thin hairy skin covers most of the body. Glabrous ... Paper money skin, Red skin, Sandpaper skin, Second Skin®, Spray-on skin, Swiss cheese skin, Washerwoman skin.. skin (skin) [TA ...
Outer epithelium (glabrous skin of the prepuce). The outer epithelium of the prepuce consists of stratified squamous cells that ... 6. Merkel cells within the basal layer of the prepuce outer glabrous skin. Cytokeratin 20 stain x400.. ... and are found in glabrous skin ; they have been reported in the clitoris and can be identified in the male prepuce (Fig. 6) [49 ... dermis and outer glabrous skin [10].. The embryology of the penile prepuce has been controversial since the original account ...
Denervation in man often results in shiny, dry, thin skin. A previous study has shown that the epidermis of glabrous skin in ... N2 - Denervation in man often results in shiny, dry, thin skin. A previous study has shown that the epidermis of glabrous skin ... AB - Denervation in man often results in shiny, dry, thin skin. A previous study has shown that the epidermis of glabrous skin ... glabrous skin, muscle innervation, nonhuman, priority journal, rat, rhizotomy, sciatic nerve, skin nerve, sympathectomy, Actins ...
Glabrous skin (palmoplantar, subungueal). Flat Nodule Plaque. Irregular, poorly circumscribed pigmentation. Radial growth phase ... A. F. Alexis and K. Heal, "Skin cancer in skin of color," Cutis, vol. 89, no. 5, pp. 208-211, 2012. View at: Google Scholar*S. ... Skin Self Examination. Skin self-examination has great potential as a simple, convenient method of screening for CM and ... The main host risk factors are the number of melanocytic nevi on the skin, skin type, family history, and genetic ...
2. A sample of 334 low threshold mechanoreceptive units innervating the glabrous skin area of the hand were studied. In ... 2. A sample of 334 low threshold mechanoreceptive units innervating the glabrous skin area of the hand were studied. In ... Tactile sensibility in the human hand: relative and absolute densities of four types of mechanoreceptive units in glabrous skin ... whereas the PC and SA II units were almost evenly distributed over the whole glabrous skin area.. 5. The spatial distribution ...
The aim of this study was to assess the effect of hairy and glabrous skin stimulation on neural transmission of nociceptive ... This finding provides strong evidence that first pain to heat does exist in glabrous skin, and suggests that similar ... Laser stimulation of hairy and glabrous skin at the same energy elicited remarkably similar psychophysical ratings and LEPs. ... had to be applied to glabrous skin in order to achieve psychophysical ratings similar to those obtained following hairy skin ...
Resurfacing glabrous skin defects in the hand: the thenar base donor site.. GLABROUS SKIN GRAFT FOR PALMER SKIN DEFECTS; SIMPLE ... Patients were covered and care was taken that the skin temperature of the thenar region did not fall below 32degC.. The effect ...
... and that ligand-guided laser ablation of TrkB+ sensory neurons in the mouse skin attenuates this hypersensitivity. ... perform molecule-guided laser ablation of these neurons and achieve long-term retraction of TrkB-positive neurons from the skin ... on d glabrous and e hairy skin, f hot plate test (t-test; p = 0.914), g radiant heat test on glabrous and hairy skin (t-test; p ... l Section from human glabrous skin stained with antibodies against TrkB (red) and NF200 (green), and DAPI (blue). Scale bars, a ...
... and located much closer to the surface of the skin. Free nerve endings, the most common type of skin receptor, are cell-sized, ... The main four mechanoreceptors in hairless skin areas are Pacinian corpuscles, Meissners corpuscles, Merkels discs, and ... and can be found at a variety of different depths in the skin. Some mechanoreceptors, such as the Pacinian copulscule, which ... hairless skin, contains the finest receptors. Called mechanoreceptors, these translate physical force into nerve impulses. ...
Location: glabrous skin.. • Motion detection (skin motion); grip control; low frequency vibrations. ...
... hairy and glabrous skin (hairless).[4] The adjective cutaneous literally means "of the skin" (from Latin cutis, skin). ... Skin color[edit]. Main article: Human skin color. Human skin shows high skin color variety from the darkest brown to the ... Diseases of the skin include skin infections and skin neoplasms (including skin cancer). ... Skin repair. References[edit]. *^ a b c d e f "Skin care" (analysis), Health-Cares.net, 2007, webpage: HCcare Archived 12 ...
Single unit analysis of mechanoreceptor activity from the human glabrous skin.. Perfil clinico de las internaciones por herpes ... Physiology) physiol a sensory receptor, as in the skin, that is sensitive to a mechanical stimulus, such as pressure ...
In glabrous (hairless) skin, there are four principal types of mechanoreceptors, each shaped according to its function. The ... There are four main types of mechanoreceptors in glabrous, or hairless, mammalian skin: lamellar corpuscles (Pacinian ... The Slowly Adapting type 2 (SA2) mechanoreceptors, with the Ruffini corpuscle end-organ, respond to skin stretch, but have not ... They are located in the skin, like other cutaneous receptors. They are all innervated by Aβ fibers, except the mechanorecepting ...
However, touch directed to glabrous skin compared to hairy skin will activate different types of afferent mechanoreceptors. ... However, touch directed to glabrous skin compared to hairy skin will activate different types of afferent mechanoreceptors. ... to both glabrous (palm) and hairy (arm) skin, where a soft brush was used as the stimulus. There were two active touch ... to both glabrous (palm) and hairy (arm) skin, where a soft brush was used as the stimulus. There were two active touch ...
Glabrous Dermal Grafting: A 12-Year Experience with the Functional and Aesthetic Restoration of Palmar and Plantar Skin Defects ... THE FISH-SKINNING MACHINE: AN UNUSUAL SOURCE OF HAND TRAUMA. Waterston, Stuart W.; Holmes, John D. ... SKIN ULCERATION IN TRIGEMINAL TROPHIC SYNDROME: REPORT OF A LESION OCCURRING 22 YEARS LATER. Yiacoumettis, Andreas; Vlachos, ... A SIMPLE BOLSTERING METHOD FOR OPTIMIZING SKIN GRAFT TAKE ON THE SHAFT OF THE PENIS. Ferguson, Robert E. H. Jr.; Schaeffer, ...
C, PLAP staining in whole-mount paw skin. Dashed line shows boundary between hairy (right) and glabrous (left) skin. D, In 14 ... G, Staining in a section of skin from the hindpaw of a TRPV1Cre/R26R-EYFP mouse for EYFP (left, green) and TRPV1 (middle, red ... μm sections of paw skin, we occasionally observed PLAP+ fibers extending into the outermost layer of the epidermis (arrowheads ...
The effects of skin temperature on the psychophysical responses to vibration on glabrous and hairy skin. J. Acoust. Soc. Am. 80 ... Knibestöl, M. (1973). Stimulus-response functions of rapidly adapting mechanoreceptors in the human glabrous skin area. J. ... By adding an accurate skin mechanics model to compute the skin indentations from stimuli, the current model has the capability ... relative and absolute densities of four types of mechanoreceptive units in glabrous skin. J. Physiol. 286, 283-300. ...
Pityriasis rosea is characterized by small, fawn-colored lesions distributed along skin cleavage lines. Treatment is ... Scaly, annular, erythematous plaques or papules on glabrous skin. Topical and systemic antifungals ... M. leprae grows best at 35.6°C (96.0°F) and thus has a predilection for cooler parts of the body, such as skin, peripheral ... Because the lesions follow the skin cleavage lines, they have the characteristic appearance of a Christmas tree.1,6-8 ...
Typically affects glabrous skin (smooth and bare). *c. Diagnosis: Usually diagnosed clinically, but a KOH preparation or fungal ... 2. Staph scalded skin syndrome. *a. Pathogenesis: Staphylococcus aureus infections of the skin with hematogenous dissemination ... B. Secondary Skin Lesions. *1. Scale: Small, thin plates shedding from the surface of the skin ... Spread by skin-to-skin contact. *b. Clinical presentation: Dome-shaped, often umbilicated, translucent to white papules that ...
2001) Response properties of mechanoreceptors and nociceptors in mouse glabrous skin: an in vivo study. J Neurophysiol 85:1561- ... 1998) Cold-induced pain and prickle in the glabrous and hairy skin. Pain 75:47-57. ... Recording of skin temperature. Surface skin temperature on the hindpaw was recorded using a K-type thermocouple (Physitemp) ... Acetone and ethyl chloride evoke very different skin cooling profiles in vivo. A, Example traces of surface and subsurface skin ...
Are You Confident of the Diagnosis? Lichen planus (LP) is a papulosquamous disorder of the skin, mucous membranes, hair, and ... Lesions of the glabrous skin…. *. Already have an account? Sign in here. ...
Westling G, Johansson RS (1987) Responses in glabrous skin mechanoreceptors during precision grip in humans. Exp Brain Res 66: ... relative and absolute densities of four types of mechanoreceptive units in the glabrous skin. J Physiol (Lond) 186:283-300 ... Sensitivity to edges of mechanoreceptive afferent units innervating the glabrous skin of the human hand. Bran Res 244:27-32 ...
Percentages of avidin-positive mast cells that also were tdTomato-positive: glabrous skin, 97.5%; hairy skin, 90.1%; trachea, ... glabrous skin, 99.2%; hairy skin, 100%; trachea, 98.3%; heart, 99%. n=3 mice and ,300 cells counted/tissue, except n=2 and ,100 ... over 3000 μm2 and 1000 μm2 counted for each genotype for hairy and glabrous skin, respectively; over 10,000 peritoneal cells ... The mast cell numbers and the histamine content of tracheal and skin tissue was not different between wild type and MrgprB2MUT ...
  • The skin consists of two main parts: an outer layer, the epidermis , and an inner layer, the corium (or dermis ). (thefreedictionary.com)
  • Underneath the epidermis is the thicker part of the skin, the corium, or dermis, which is made up of connective tissue that contains blood vessels and nerves. (thefreedictionary.com)
  • A previous study has shown that the epidermis of glabrous skin in the rat becomes approximately 40% thinner within 1 week following sciatic nerve transection, but which nerve fiber type or types influence epidermal thickness is unknown. (elsevier.com)
  • Skin is composed of three primary layers: the epidermis , the dermis and the hypodermis . (wikipedia.org)
  • Epidermis , "epi" coming from the Greek meaning "over" or "upon", is the outermost layer of the skin. (wikipedia.org)
  • D , In 14 μm sections of paw skin, we occasionally observed PLAP+ fibers extending into the outermost layer of the epidermis (arrowheads). (jneurosci.org)
  • The epidermis helps the skin regulate body temperature. (wikipedia.org)
  • For example, sensory denervation of skin results in alterations in skin anatomy, including thinning of the epidermis, decreases in epidermal proliferation, and changes in the gene expression of Langerhans cells (Huang et al. (google.com)
  • The epidermis is the epithelial tissue layer of skin. (siumed.edu)
  • Cutaneous melanoma (CM) is the most common cause of mortality among skin cancer in Caucasian populations (incidence rates per 100,000 patient years vary between 21.9 in the United States to 55.9 in Australian males). (hindawi.com)
  • [4] The adjective cutaneous literally means "of the skin" (from Latin cutis , skin). (wikipedia.org)
  • They are located in the skin, like other cutaneous receptors . (wikipedia.org)
  • They had cutaneous lesions on the glabrous skin or the scalp. (wikipedia.org)
  • About 30% have cutaneous myxomas which are soft skin-colored or waxy papules. (renalandurologynews.com)
  • Immune-mediated loss of transgene expression in skin: implications for cutaneous gene therapy. (semanticscholar.org)
  • Excessive Peptidergic Sensory Innervation of Cutaneous Arteriole-Venule Shunts (AVS) in the Palmar Glabrous Skin of Fibromyalgia Patients: Implications for Widespread Deep Tissue Pain and Fatigue. (prohealth.com)
  • Multimolecular immunocytochemistry to assess different types of cutaneous innervation in 3 mm skin biopsies from glabrous hypothenar and trapezius regions. (prohealth.com)
  • Cutaneous lymphoma is a general term for cancers of the lymphocytes that primarily involve the skin. (rarediseases.org)
  • Similar nociceptive afferents mediate psychophysical and electrophysiological responses to heat stimulation of glabrous and hairy skin in humans. (ox.ac.uk)
  • When heat stimuli are applied to primate hairy skin, first pain sensation is mediated by type-II A-fibre nociceptors (II-AMHs). (ox.ac.uk)
  • The aim of this study was to assess the effect of hairy and glabrous skin stimulation on neural transmission of nociceptive inputs elicited by different kinds of thermal heating. (ox.ac.uk)
  • Laser stimulation of hairy and glabrous skin at the same energy elicited remarkably similar psychophysical ratings and LEPs. (ox.ac.uk)
  • This finding provides strong evidence that first pain to heat does exist in glabrous skin, and suggests that similar nociceptive afferents, with the physiological properties of II-AMHs, mediate first pain to heat stimulation of glabrous and hairy skin in humans. (ox.ac.uk)
  • P2 wave, -44%) than CHEPs following hairy skin stimulation. (ox.ac.uk)
  • There are two general types of skin, hairy and glabrous skin (hairless). (wikipedia.org)
  • There are also mechanoreceptors in hairy skin, and the hair cells in the receptors of primates like rhesus monkeys and other mammals are similar to those of humans and also studied even in early 20th century anatomically and neurophysiologically. (wikipedia.org)
  • However, touch directed to glabrous skin compared to hairy skin will activate different types of afferent mechanoreceptors. (frontiersin.org)
  • In the present study, we used functional magnetic resonance imaging (fMRI) to elucidate the cortical differences in the neural signal of touch representations during active, self-touch and passive touch from another, to both glabrous (palm) and hairy (arm) skin, where a soft brush was used as the stimulus. (frontiersin.org)
  • There are differences in the types of low-threshold mechanoreceptors found in the glabrous skin of the palm compared to the hairy skin on the arm (for an overview, see Macefield, 2005 ). (frontiersin.org)
  • The mechanoreceptors on the glabrous skin allow high discriminatory abilities for touch, whereas the input from hairy skin does not give such discrimination. (frontiersin.org)
  • Dashed line shows boundary between hairy (right) and glabrous (left) skin. (jneurosci.org)
  • Tensile and compressive responses of nociceptors in rat hairy skin. (semanticscholar.org)
  • Differing neurophysiologic mechanosensory input from glabrous and hairy skin in juvenile rats. (semanticscholar.org)
  • Responses of slowly adapting type II afferent fibres in cat hairy skin to vibrotactile stimuli. (semanticscholar.org)
  • Simultaneous recordings of SSNA from peroneal and tibial nerves revealed that SSNA leading to hairy skin discharged differently from that leadin- to glabrous skin. (angelfire.com)
  • Vasodilator activity works only in SSNA leading to hairy skin, btit not to glabrous skin, concomitantly with sudomotor activity. (angelfire.com)
  • The scientists also hypothesized that because hairy skin is more sensitive to thermal stimuli, it would be more perceptive to wetness than glabrous skin (e.g., palms of the hands, soles of the feet), which is more sensitive to tactile stimuli. (medindia.net)
  • They tested sites on the subjects' forearms (hairy skin) and fingertips (glabrous skin). (medindia.net)
  • The research team also found that the subjects were less sensitive to wetness when the A-nerve activity was blocked and that hairy skin is more sensitive to wetness than glabrous skin. (medindia.net)
  • Optimizing sensitivity, penetration and contrast enabled unprecedented visualization of micro-structural morphology underneath the glabrous skin, hairy skin and in scar tissue. (spie.org)
  • Whisker motion was encoded best by whisker mechanoreceptors, but also by those innervating whisker pad hairy skin and supraorbital vibrissae. (elifesciences.org)
  • Here, we addressed this question by recording whisker motion and electrophysiological responses from primary mechanoreceptor afferents innervating several distinct structures on the face, including regions of hairy skin, vibrissae other than the mystacial whiskers, and jaw muscles ( Figure 1A ). (elifesciences.org)
  • We find that a subset of hairy skin mechanoreceptors encodes whisker motion at levels comparable to whisker mechanoreceptors. (elifesciences.org)
  • The hairy skin of the dorsal site is thin, soft and pliable. (cosmeticsandtoiletries.com)
  • Skin graft was harvested from the hypothenar eminence using simple surgical blade. (thefreelibrary.com)
  • 3 mm skin biopsies will be obtained from the dominant trapezius and the glabrous hypothenar area of the hand. (clinicaltrials.gov)
  • AVS were identified in hypothenar skin biopsies from 18/24 FM patient and 14/23 control subjects. (prohealth.com)
  • 2. One hundred and one slowly adapting receptors with receptive fields in the glabrous skin area were studied. (nih.gov)
  • One type of cells that might mediate the actions of CB 2 receptor-selective agonists is keratinocytes, which have been reported to express CB 2 receptors ( 11 ) and to contain endogenous opioid peptides ( 12 - 14 ) and which are found in abundance in skin, where nociceptive stimuli have been applied when testing the antinociceptive effects of CB 2 receptor-selective agonists. (pnas.org)
  • Computational modeling indicates that surface pressure can be reliably conveyed to tactile receptors even amidst changes in skin mechanics. (semanticscholar.org)
  • A new study shows how human sensitivity to wetness plays a role in many aspects of daily life and feeling that something is wet is quite a feat because our skin does not have receptors that sense wetness. (medindia.net)
  • The commonality of all touch sensing systems is that touch experience is mediated by specialised receptors embedded in the integument-the outer protective layers of the animal such as the mammalian skin or the arthropod cuticle. (scholarpedia.org)
  • Previous studies on joint position sense have indicated that proprioception, which includes information from muscle, skin and joint receptors 10 , is particularly affected by cryotherapy 8 . (scielo.br)
  • These three regions were chosen for their predominance of skin, joint and muscle receptors, respectively, which might differentially influence gait initiation following cryotherapy. (scielo.br)
  • 7 In the 1990s, it was discovered that peripheral nerve endings in skin contain glutamate receptors that are involved in nociception. (practicalpainmanagement.com)
  • This information is registered by various types of receptors, e.g. mechanoreceptors (pressure and vibration), thermoreceptors (temperature), and nociceptors (pain and damage) distributed all over the body with variable density and located in the various layers of the skin (Johansson and Westling, 1984). (scholarpedia.org)
  • The skin is innervated by an array of functionally distinct populations of mechanoreceptors that can be distinguished by their conduction velocity, response properties, mechanical threshold, and the type of end organ that they innervate 17 . (nature.com)
  • The main four mechanoreceptors in hairless skin areas are Pacinian corpuscles, Meissner's corpuscles, Merkel's discs, and Ruffini corpuscles. (answers.com)
  • Different mechanoreceptors are specialized to detect different touch sensations, and can be found at a variety of different depths in the skin. (answers.com)
  • In glabrous (hairless) skin, there are four principal types of mechanoreceptors, each shaped according to its function. (wikipedia.org)
  • The Slowly Adapting type 2 (SA2) mechanoreceptors , with the Ruffini corpuscle end-organ , respond to skin stretch, but have not been closely linked to either proprioceptive or mechanoreceptive roles in perception. (wikipedia.org)
  • Active, self-touch and the passive touch from an external source engage comparable afferent mechanoreceptors on the touched skin site. (frontiersin.org)
  • The brain receives afferent information from the activation of mechanoreceptors in the skin during interactions with the environment. (frontiersin.org)
  • A low intensity vertically applied stimulus of 1 second (s) is expected to activate predominantly rapidly adapting A-beta mechanoreceptors thus recruiting the same peripheral substrate as a horizontally moving brush on top of the skin. (degruyter.com)
  • Touch begins with the activation of low-threshold mechanoreceptors (LTMRs) in the skin. (elifesciences.org)
  • Preliminary data suggests that dual treatment of footpad skin with SF and selective estrogen receptor β agonist diarylpropionitrile (DPN) prevents the development of PPK lesions in female Krt16-/- mice. (jhu.edu)
  • Pityriasis rosea is characterized by small, fawn-colored lesions distributed along skin cleavage lines. (aafp.org)
  • Microsporum gallinae infection is diagnosed by culturing the scrapings from skin lesions. (wikipedia.org)
  • In rare cases, immunocompromised individuals form severe dissemination on the skin, instead of small localized lesions as a result of handling infected animals. (wikipedia.org)
  • The plaques of seborrheic dermatitis occurring on glabrous skin are often rather sharply marginated and for this reason are easily mistaken for papulosquamous lesions. (articlebiz.com)
  • When disease progresses, thicker lesions develop on the skin. (rarediseases.org)
  • Lesions of the glabrous skin are most commonly pruritic papules, but many subtypes have been described (see Table I ). (clinicaladvisor.com)
  • Epidermoid cysts are common benign lesions of hair-bearing, and less often glabrous skin. (pubfacts.com)
  • Skin lesions are often submitted to oral and maxillofacial pathology practices. (pubfacts.com)
  • An IRB-approved retrospective search of skin lesions diagnosed at University of Florida oral and maxillofacial pathology biopsy service between 1994 and 2015 was performed. (pubfacts.com)
  • The male prepuce is formed by a midline collision of ectoderm, neuroectoderm and mesenchyme, resulting in a pentalaminar structure composed of a squamous mucosal epithelium lamina propria (corion) dartos muscle, dermis and outer glabrous skin [ 10 ]. (cirp.org)
  • This organ is located in the dermis and maintains stem cells, which not only re-grow the hair after it falls out, but also are recruited to regrow skin after a wound. (wikipedia.org)
  • The dermis is the connective tissue layer of skin. (siumed.edu)
  • Human skin shares anatomical, physiological, biochemical and immunological properties with other mammalian lines, especially pig skin . (wikipedia.org)
  • A novel ultrastructure on the corneocyte surface of mammalian nasolabial skin. (lu.se)
  • Skin grafts can be harvested from different parts of the body like thighs, arms, groin, scalp, palm and sole etc3. (thefreelibrary.com)
  • Tinea corporis refers to a dermatophytosis or superficial fungal infection of the skin, other than on the hands, feet, scalp, face or groin. (aafp.org)
  • Microsporum gallinae has been isolated from the scalp, and smooth skin in human populations. (wikipedia.org)
  • In both psoriasis and seborrheic dermatitis, extension onto the nonhairy, marginal skin surrounding the scalp is occasionally seen. (articlebiz.com)
  • The impulse responses to perpendicular sinusoidal skin displacements were recorded from 4 different types of mechanoreceptive different units innervating the glabrous skin of the human hand. (nih.gov)
  • Tactile sensibility in the human hand: relative and absolute densities of four types of mechanoreceptive units in glabrous skin. (mariusblomstervik.no)
  • Epidermal thickness of the glabrous plantar skin of the foot was measured to verify the specificity and reliability of each animal model, the relevant regions of the peripheral nervous system were examined by light or electron microscopy or both. (elsevier.com)
  • 2 We have shown previously that incised deep tissue rather than skin has importance in the genesis of spontaneous activity in pain-transmitting pathways and nonevoked guarding behavior after plantar incision in rats. (asahq.org)
  • Georgopoulos, AP 1976, ' Functional properties of primary afferent units probably related to pain mechanisms in primate glabrous skin ', Journal of neurophysiology , vol. 39, no. 1, pp. 71-83. (umn.edu)
  • In contrast, the reported absence of first pain and II-AMH microneurographical responses when heat stimuli are applied to the hand palm has led to the notion that II-AMHs are lacking in this primate glabrous skin. (ox.ac.uk)
  • A complex sensory organ in the nose skin of the prosimian primate Lemur catta. (lu.se)
  • Since the 1960s, malignant melanoma incidence has increased in Caucasian populations, and consequently this neoplasm has become one of the most frequent cancer in fair-skinned populations. (hindawi.com)
  • The fair skinned patient commonly notes that skin especially on the face, hands, arms or other exposed skin will burn very easily in the springtime when first spending hours in the sunlight. (psychiatryadvisor.com)
  • This diagram of dermatomes that represent sensory innervation of the skin is included to illustrate that depigmentation observed in patients with unilateral (segmental) vitiligo does not correspond to sensory dermatomes. (psychiatryadvisor.com)
  • The excessive sensory innervation to the glabrous skin AVS is a likely source of severe pain and tenderness in the hands of FM patients. (prohealth.com)
  • These findings are consistent with the thickness-dependent delay and attenuation of the temperature waveform at nociceptor depth when conductive heating is applied, and suggest that the previously reported lack of first pain and microneurographical II-AMH responses following glabrous skin stimulation could have been the result of a search bias consequent to the use of long-wavelength radiant heating (i.e. (ox.ac.uk)
  • This stimulation was prevented by AM630, a CB 2 cannabinoid receptor-selective antagonist and was not observed in skin from CB 2 cannabinoid receptor-deficient mice. (pnas.org)
  • A compression/ischemia-induced (differential) nerve block in conjunction with repeated quantitative sensory testing of A-delta and C-fibre function using cold and warm stimuli was used to assess which nerve fibre population that contributes to pain at perception threshold level using 1 s (vF1) and 10 s (vF10) von Frey filament stimulation of the skin. (degruyter.com)
  • These results suggest that selective loss of both sensory and motor fibers to the hind limb can contribute to reducing epidermal thickness in rat foot glabrous skin. (elsevier.com)
  • The thickness of the skin varies considerably over all parts of the body, and between men and women and the young and the old. (wikipedia.org)
  • They also observed the role of A-nerve fibers-sensory nerves that carry temperature and tactile information from the skin to the brain-and the effect of reduced nerve activity on wetness perception. (medindia.net)
  • Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. (semanticscholar.org)
  • The neural response to stimuli of varying skin indentation amplitudes was analyzed. (nih.gov)
  • The high threshold units were categorized by observing their responses to mechanical and thermal (53 and 8°C) stimuli applied to their receptive fields in the glabrous skin of the hand. (umn.edu)
  • Rapidly adapting type 1 (RA1) afferents respond to stimuli that bump against the skin and convey information about motion across the skin ( Johansson and Westling, 1987 ). (frontiersin.org)
  • Specialized peripheral sensory neurons known as nociceptors alert us to potentially damaging stimuli at the skin by detecting extremes in temperature and pressure and injury-related chemicals, and transducing these stimuli into long-ranging electrical signals that are relayed to higher brain centers. (jci.org)
  • Here, we review the nociceptive aspect of pain perception, focusing on nociceptors innervating the skin and subserving exteroception of noxious stimuli. (jci.org)
  • In humans, skin pigmentation varies among populations, and skin type can range from dry to non-dry and from oily to non-oily. (wikipedia.org)
  • Skin has mesodermal cells, pigmentation , such as melanin provided by melanocytes , which absorb some of the potentially dangerous ultraviolet radiation (UV) in sunlight . (wikipedia.org)
  • Human skin pigmentation varies among populations in a striking manner. (wikipedia.org)
  • At the University of Southampton, scientists have identified key characteristics that enhance a nanoparticle's ability to penetrate skin, in a milestone study which could have major implications for the delivery of drugs. (medindia.net)
  • On the human body, glabrous skin is external skin that is naturally hairless. (wn.com)
  • The human skin is the outer covering of the body and is the largest organ of the integumentary system . (wikipedia.org)
  • [1] Human skin is similar to most of the other mammals ' skin, and it is very similar to pig skin. (wikipedia.org)
  • [2] [3] Though nearly all human skin is covered with hair follicles , it can appear hairless. (wikipedia.org)
  • [7] Such skin variety provides a rich and diverse habitat for bacteria that number roughly 1000 species from 19 phyla , present on the human skin. (wikipedia.org)
  • [2] [3] and pig skin and human skin have similar physical responses to various growth factors. (wikipedia.org)
  • In terms of surface area, the skin is the second largest organ in the human body (the inside of the small intestine is 15 to 20 times larger). (wikipedia.org)
  • For the average adult human, the skin has a surface area of between 1.5-2.0 square metres (16.1-21.5 sq ft. (wikipedia.org)
  • [12] [ better source needed ] The average human skin cell is about 30 micrometres in diameter, but there are variants. (wikipedia.org)
  • Single unit analysis of mechanoreceptor activity from the human glabrous skin. (thefreedictionary.com)
  • For the average adult human, the skin has a surface area of between 1.5-2.0 square metres (16-22 sq ft). (wikipedia.org)
  • AM1241 stimulated β-endorphin release from rat skin tissue and from cultured human keratinocytes. (pnas.org)
  • The aim of this introductory overview is to give selected examples of research on important model organisms from various classes of the animal kingdom, ranging from the skin of worms to the feelers of insects, and from the whiskers of a rat to the human hand. (scholarpedia.org)
  • The human body, apart from areas of glabrous skin, is covered in follicles which produce thick terminal and fine vellus hair . (wikipedia.org)
  • Mucosal Human Papillomavirus Detection and TP53 Immunohistochemical expression in Non-Melanoma Skin Cancer in Tunisian Patients. (amedeo.com)
  • Human melanocytes have been extensively studied, but a melanocyte stem cell reservoir in glabrous skin has not yet been found. (springer.com)
  • Human skin is similar to that of most other mammals except that it is not protected by a pelt and appears hairless but in fact almost all human skin is covered with hair follicles. (medformula.com)
  • The human skin is a rich environment for microbes. (medformula.com)
  • High speed, three-dimensional optical coherence tomography (3D OCT) at 800nm, 1060nm and 1300nm with approximately 4μm, 7μm and 6μm axial and less than 15μm transverse resolution is demonstrated to investigate the optimum wavelength region for in vivo human skin imaging in terms of contrast, dynamic range and penetration depth. (spie.org)
  • The sebaceous glands of a human fetus in utero secrete a substance called Vernix caseosa, a "waxy" or "cheesy" white substance coating the skin of newborns. (bionity.com)
  • Experimental infection of the skin in the hamster simulating human impetigo. (healio.com)
  • 3. The locations of the receptive fields of individual units were determined and the relative unit densities within various skin regions were calculated. (mariusblomstervik.no)
  • 4. The differences in over-all density were essentially accounted for by the two types of units characterized by small and well defined receptive fields, the RA and SA I units, whereas the PC and SA II units were almost evenly distributed over the whole glabrous skin area. (mariusblomstervik.no)
  • the greatest number is in the palms of the hands and soles of the feet, where the skin is thickest. (thefreedictionary.com)
  • Editor's Comment: In this study, researchers measured the blood flow in the palms (glabrous skin) of people with fibromyalgia and controls. (prohealth.com)
  • A branched type of acinar gland, these glands exist in humans throughout the skin except in the palms of the hands and soles of the feet . (bionity.com)
  • The units were classified as type SA-I and type SA-II largely on the basis of their responses to lateral stretching of the skin. (nih.gov)
  • In the present study, to test the hypothesis that cigarette smoking and physical exercise induce different influences on peripheral vasomotor control after mental stress, we examined the physiological responses, including skin vasomotor responses, to smoking and exercise in six healthy smokers. (biomedsearch.com)
  • Comparison of histologic features of photodamaged skin and melanoma in situ after staged surgical excision with concurrent scouting biopsies. (amedeo.com)
  • Expert-reviewed information summary about the genetics of skin cancer - basal cell carcinoma, squamous cell carcinoma, and melanoma - including information about specific gene mutations and related cancer syndromes. (oncolink.org)
  • Melanoma is less common than nonmelanoma skin cancer, but 5% to 10% of all melanomas arise in multiple-case families and may be inherited in an autosomal dominant fashion. (oncolink.org)
  • Most of the psychosocial literature about hereditary skin cancers has focused on patients with familial melanoma. (oncolink.org)
  • Skin morphology is unique in the palm area: It is glabrous, relatively thick and lighter than the skin of other body parts. (cosmeticsandtoiletries.com)
  • Evidence for different mechanisms of primary and secondary hyperalgesia following heat injury to the glabrous skin" Brain (1984), 107, 1179-1188. (patentgenius.com)
  • Conclusion: Coverage of small palmer wounds with glabrous skin grafts had shown excellent cosmetic and functional outcome along with minimal donor site morbidity and easy technique. (thefreelibrary.com)
  • One of the major concerns of skin grafting remains poor color match in the recipient site and donor site morbidity4. (thefreelibrary.com)
  • When area with glabrous skin is grafted with non glabrous skin it results in poor color and texture match, unsightly donor site scar, contractures, hypertrophy, sub graft fibrosis, painful hyperkeratosis buildup in periphery of graft6,7. (thefreelibrary.com)
  • This article is about skin in humans. (wikipedia.org)
  • Thermogenic and psychogenic sweating in humans: Identifying eccrine glandular recruitment patterns from glabrous and non-glabrous skin surfaces. (nih.gov)
  • Importantly, glabrous AVS regulate blood flow to the skin in humans for thermoregulation and to other tissues such as skeletal muscle during periods of increased metabolic demand. (prohealth.com)
  • In humans at rest, a skin temperature of around 33°C is experienced as thermoneutral, with lower temperatures felt as cool/cold and higher temperatures as warm/hot (Vriens, Nilius, & Voets, 2014 ). (oxfordhandbooks.com)
  • Perspiration helps regulate body temperature as well, because cooling of the skin occurs when sweat evaporates. (thefreedictionary.com)
  • Seborrheic dermatitis also occurs on nonhairy (glabrous) skin. (articlebiz.com)
  • Callus - wikipedia, free encyclopedia, A corn (or clavus, plural clavi) is a specially shaped callus of dead skin that usually occurs on thin or glabrous (hairless and smooth) skin surfaces, especially on. (amazonaws.com)
  • The hair and nails are outgrowths of the skin. (thefreedictionary.com)
  • Lichen planus (LP) is a papulosquamous disorder of the skin, mucous membranes, hair, and nails. (renalandurologynews.com)
  • It obtains nutrients from keratin-rich skin, nails and hair, releasing enzymes during its digestion that elicit a host immune response as seen in ringworm. (wikipedia.org)
  • Occasionally the glabrous skin or nails are infected. (slideserve.com)
  • Dynamic mechanical allodynia (DMA) is evoked by a normally innocuous light moving mechanical stimulus on the skin and static mechanical allodynia (SMA) by a sustained, normally innocuous pressure against the skin. (degruyter.com)
  • Recent work has pointed to the hair follicle as the main repository of multipotent stem cells in skin. (semanticscholar.org)
  • Cross-section of all skin layers.A hair follicle with associated structures. (bionity.com)
  • Glabrous characteristics of leaves, stems, and fruit are commonly used in plant keys . (wn.com)
  • The 2 bases that are commonly used are Lipoderm and pluronic lecithin organogel (PLO), transdermal bases used by compounding pharmacies to administer medications through the skin. (practicalpainmanagement.com)
  • In varying degrees most mammals have some skin areas without natural hair . (wn.com)
  • For other mammals, see skin . (wikipedia.org)
  • The sebaceous glands are glands found in the skin of mammals. (bionity.com)
  • The greater response of muscle tissue to H 2 O 2 may help explain why incision that includes deep muscle but not skin incision alone produces spontaneous activity in nociceptive pathways. (asahq.org)
  • Synthetic smooth muscle in the outer blood plexus of the rhinarium skin of Lemur catta L. (lu.se)
  • The objective of the present study was to obtain the temporal and spatial temperature distributions in the skin caused by the irradiation of a short-pulse laser. (spiedigitallibrary.org)
  • These temperature-sensitive nociceptor neurons become activated when the temperature at their free endings in the skin or mucosae reaches noxious levels, provoking acute pain and rapid avoidance reflexes. (oxfordhandbooks.com)
  • Sensibility to cold is significantly decreased 10 to 30 minutes after the block, even with a reduction in the skin temperature on the blocked side. (nysora.com)
  • Hair grows from the roots, but the hair cells die while still in the follicles, and the closely packed remains that are pushed upward form the hair shaft that is seen on the surface of the skin. (thefreedictionary.com)
  • Support for this hypothesis is offered by the observation that when a man with no skin disease on the face grows a beard, he may then suddenly develop seborrheic dermatitis in that area. (articlebiz.com)
  • The skin has up to seven layers of ectodermal tissue and guards the underlying muscles , bones , ligaments and internal organs . (wikipedia.org)
  • Severely damaged skin will try to heal by forming scar tissue . (wikipedia.org)
  • In order for the skin layer to remain anchored to the bone structure, a layer of connective fibrous tissue (fascia) links the skin with the skeleton. (healthline.com)
  • Mechanisms of wound reepithelialization: hints from a tissue-engineered reconstructed skin to long-standing questions. (google.com)
  • A keloid is a type of scar which results in an overgrowth of tissue at the site of a healed skin injury. (bionity.com)
  • Thus, overall, the thermal pain thresholds of intact, healthy skin are well tuned to signal temperatures that are capable of causing tissue damage. (oxfordhandbooks.com)
  • The microscopic anatomy of skin reflects this functional complexity, with each functional specialization implemented by particular features of cell and tissue structure. (siumed.edu)
  • Beneath the skin lies the hypodermis -- connective tissue which may be adipose or fibrous , depending on location. (siumed.edu)
  • H 2 O 2 has a variety of actions in skin wounds but has been rarely studied in deep muscle tissue. (asahq.org)
  • Glabrous features may be an important means of identifying flora species. (wn.com)
  • 2. A sample of 334 low threshold mechanoreceptive units innervating the glabrous skin area of the hand were studied. (mariusblomstervik.no)
  • risk greatest in large hemangiomas and those located in skin creases, particularly the diaper area. (unboundmedicine.com)
  • They can occur as a result of severe acne or chickenpox scarring, infection at a wound site, repeated trauma to an area, excessive skin tension during wound closure or a foreign body in a wound. (bionity.com)
  • 4. In an apparatus according to claim 3, and wherein the field electrode means comprise one field electrode to be placed adjacent to skin area on the hips, buttocks, and lower back of the subject, and another field electrode to be placed adjacent to the skin area on the back side of the thighs and knees of the subject. (freepatentsonline.com)
  • The electrode allows the currents to be monitored without the area of skin having to be shaved. (google.com)
  • The male prepuce also provides adequate mucosa and skin to cover the entire penis during erection. (cirp.org)
  • Sebaceous glands are also found in non-haired areas (glabrous skin) of eyelids , penis, labia minora, and nipples . (bionity.com)
  • The purpose of this study is to examine the characteristics of the nerves and the small veins in the skin of people with fibromyalgia. (clinicaltrials.gov)
  • Colony growth is very slow, glabrous to lightly downy,white, sometimes yellow or grey on the surface without any characteristic pigment on the reverse. (slideserve.com)
  • What's the defining characteristic of glabrous skin? (statnews.com)
  • Healing of wounds in skin and other epithelia involves a complex set of interactions between numerous components, including epithelial cells, peripheral nerves, and immune cells, as well as soluble and matrix molecules contributed by the various cell types (reviewed in Hom et al. (google.com)
  • Mechanically sensitive nociceptor afferents were studied in a preparation of isolated skin from rat leg. (semanticscholar.org)
  • In botany and mycology , a glabrous morphological feature is smooth, glossy, having no trichomes (bristles or hair-like structures), or glaucousness (see also indumentum ). (wn.com)
  • Patients present with well-demarcated, erythematous papules or plaques on the skin. (aafp.org)
  • Refractory Macrophage Activation Syndrome in the setting of Adult Onset Still's Disease with Hemophagocytic Lymphohistiocytosis Detected on Skin Biopsy treated with Canakinumab and Tacrolimus. (amedeo.com)
  • BIOPSY -- Examine and interpret a skin biopsy specimen. (siumed.edu)
  • Sebaceous glands are involved in skin problems such as acne and keratosis pilaris . (bionity.com)
  • Active cancer with the previous two years except treated basal cell carcinoma of the skin. (clinicaltrials.gov)
  • Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), which are known collectively as nonmelanoma skin cancer, are two of the most common malignancies in the United States and are often caused by sun exposure, although several hereditary syndromes and genes are also associated with an increased risk of developing these cancers. (oncolink.org)
  • The painful palmoplantar keratoderma (PPK) arising in individuals with pachyonychia congenita (PC) exhibit a significant upregulation of danger-associated molecular patterns and skin barrier regulators. (jhu.edu)
  • Material and Methods: Seventy patients of both sexes with hand defects secondary to trauma, burn or surgery who underwent coverage with glabrous skin were included in the study. (thefreelibrary.com)
  • They collect fluid containing water, salt, and waste products from the blood and carry it away in canals that end in pores on the skin surface, where it is deposited as sweat. (thefreedictionary.com)
  • [11] The average square inch (6.5 cm²) of skin holds 650 sweat glands, 20 blood vessels, 60,000 melanocytes, and more than 1,000 nerve endings. (wikipedia.org)
  • Here, the sebum traverses ducts which terminate in sweat pores on the surface of the skin. (bionity.com)