Cell Death: The termination of the cell's ability to carry out vital functions such as metabolism, growth, reproduction, responsiveness, and adaptability.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Death: Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Brain Death: A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.Attitude to Death: Conceptual response of the person to the various aspects of death, which are based on individual psychosocial and cultural experience.Caspases: A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Receptors, Death Domain: A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a death domain due to the fact that many of these receptors are involved in signaling APOPTOSIS. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Mortality: All deaths reported in a given population.Autopsy: Postmortem examination of the body.Caspase 3: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Necrosis: The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Proto-Oncogene Proteins c-bcl-2: Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Antigens, CD95: A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Infant, Newborn: An infant during the first month after birth.DNA Fragmentation: Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Cell Line, Tumor: A cell line derived from cultured tumor cells.Caspase Inhibitors: Endogenous and exogenous compounds and that either inhibit CASPASES or prevent their activation.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Autophagy: The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.In Situ Nick-End Labeling: An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.Caspase 8: A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.Infant Mortality: Postnatal deaths from BIRTH to 365 days after birth in a given population. Postneonatal mortality represents deaths between 28 days and 365 days after birth (as defined by National Center for Health Statistics). Neonatal mortality represents deaths from birth to 27 days after birth.Death Domain Receptor Signaling Adaptor Proteins: Intracellular signaling adaptor proteins that bind to the cytoplasmic death domain region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling from TUMOR NECROSIS FACTOR RECEPTORS.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.BH3 Interacting Domain Death Agonist Protein: A member of the Bcl-2 protein family that reversibly binds MEMBRANES. It is a pro-apoptotic protein that is activated by caspase cleavage.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.United Statesbcl-2-Associated X Protein: A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Reactive Oxygen Species: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Caspase 9: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.Fas Ligand Protein: A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.Enzyme Activation: Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Amino Acid Chloromethyl Ketones: Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.Homicide: The killing of one person by another.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Mice, Inbred C57BLSuicide: The act of killing oneself.Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Maternal Mortality: Maternal deaths resulting from complications of pregnancy and childbirth in a given population.Cysteine Proteinase Inhibitors: Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Poly(ADP-ribose) Polymerases: Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.bcl-X Protein: A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.bcl-Associated Death Protein: A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the activity of BCL-XL PROTEIN.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Risk: The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Programmed Cell Death 1 Receptor: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.Life Expectancy: Based on known statistical data, the number of years which any person of a given age may reasonably expected to live.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Receptors, TNF-Related Apoptosis-Inducing Ligand: Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved death domains that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.TNF-Related Apoptosis-Inducing Ligand: A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Proto-Oncogene Proteins: Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.Vital Statistics: Used for general articles concerning statistics of births, deaths, marriages, etc.Membrane Potential, Mitochondrial: The voltage difference, normally maintained at approximately -180mV, across the INNER MITOCHONDRIAL MEMBRANE, by a net movement of positive charge across the membrane. It is a major component of the PROTON MOTIVE FORCE in MITOCHONDRIA used to drive the synthesis of ATP.Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Hospitalization: The confinement of a patient in a hospital.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Receptors, Tumor Necrosis Factor: Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells.Asphyxia: A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Jurkat Cells: A CELL LINE derived from human T-CELL LEUKEMIA and used to determine the mechanism of differential susceptibility to anti-cancer drugs and radiation.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.EnglandPopulation Surveillance: Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.Hydrogen Peroxide: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.Terminal Care: Medical and nursing care of patients in the terminal stage of an illness.Bereavement: Refers to the whole process of grieving and mourning and is associated with a deep sense of loss and sadness.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Neuroprotective Agents: Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.Receptor-Interacting Protein Serine-Threonine Kinases: A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Mortality, Premature: Deaths that occur before LIFE EXPECTANCY is reached within a given population.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.DNA Damage: Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.Accidents, Traffic: Accidents on streets, roads, and highways involving drivers, passengers, pedestrians, or vehicles. Traffic accidents refer to AUTOMOBILES (passenger cars, buses, and trucks), BICYCLING, and MOTORCYCLES but not OFF-ROAD MOTOR VEHICLES; RAILROADS nor snowmobiles.Cytoprotection: The process by which chemical compounds provide protection to cells against harmful agents.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Membrane Glycoproteins: Glycoproteins found on the membrane or surface of cells.bcl-2 Homologous Antagonist-Killer Protein: A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS.Annexin A5: A protein of the annexin family isolated from human PLACENTA and other tissues. It inhibits cytosolic PHOSPHOLIPASE A2, and displays anticoagulant activity.WalesCoronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Up-Regulation: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Wounds, Gunshot: Disruption of structural continuity of the body as a result of the discharge of firearms.TNF Receptor-Associated Death Domain Protein: A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE 1. It facilitates the recruitment of signaling proteins such as TNF RECEPTOR-ASSOCIATED FACTOR 2 and FAS ASSOCIATED DEATH DOMAIN PROTEIN to the receptor complex.Poisoning: A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.JNK Mitogen-Activated Protein Kinases: A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.Recurrence: The return of a sign, symptom, or disease after a remission.Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Inhibitor of Apoptosis Proteins: A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat.Caspase 1: A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.HeLa Cells: The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Down-Regulation: A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Caspase 2: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Forensic Pathology: The application of pathology to questions of law.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Stillbirth: The event that a FETUS is born dead or stillborn.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Lung Neoplasms: Tumors or cancer of the LUNG.Cell Nucleus: Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Animals, Newborn: Refers to animals in the period of time just after birth.Caspase 7: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Tissue and Organ Procurement: The administrative procedures involved with acquiring TISSUES or organs for TRANSPLANTATION through various programs, systems, or organizations. These procedures include obtaining consent from TISSUE DONORS and arranging for transportation of donated tissues and organs, after TISSUE HARVESTING, to HOSPITALS for processing and transplantation.Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.Cysteine Endopeptidases: ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.RNA Interference: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.NF-kappa B: Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Great BritainCell Count: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.Epidemiologic Methods: Research techniques that focus on study designs and data gathering methods in human and animal populations.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Apoptotic Protease-Activating Factor 1: A CARD signaling adaptor protein that plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY). It binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX and activates INITIATOR CASPASES such as CASPASE 9.Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Breast Neoplasms: Tumors or cancer of the human BREAST.Staurosporine: An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)Cytochrome c Group: A group of cytochromes with covalent thioether linkages between either or both of the vinyl side chains of protoheme and the protein. (Enzyme Nomenclature, 1992, p539)Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Genes, bcl-2: The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.Neurotoxins: Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept.Microscopy, Fluorescence: Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.Acute Disease: Disease having a short and relatively severe course.Protein-Serine-Threonine Kinases: A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.Life Tables: Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.JapanCalcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Calpain: Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC Proteins, Signal Transducing: A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymesDNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Receptors, Tumor Necrosis Factor, Type I: A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.Antioxidants: Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.Tissue Donors: Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.Child Mortality: Number of deaths of children between one year of age to 12 years of age in a given population.SwedenChi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Microtubule-Associated Proteins: High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules.Grief: Normal, appropriate sorrowful response to an immediate cause. It is self-limiting and gradually subsides within a reasonable time.Perinatal Mortality: Deaths occurring from the 28th week of GESTATION to the 28th day after birth in a given population.Proto-Oncogene Proteins c-akt: A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
Death. (BrUp 1.2.7. trans. Müller) God of death implicitly, in eṣa vā aśvamedho ya eṣa tapati "verily, that Ashvamedha is that ... Mara (Hindu goddess), the goddess of death according to Hindu mythology. Mṛtyu-māra as death in Buddhism or Māra, a "demon" of ... Mṛtyu (from Vedic Sanskrit: मृत्यु IAST:mRtyu ; Latin cognate mortis), is a Sanskrit word meaning Death. Mṛtyu or Death is ... Yama (Sanskrit: यम) is the lord of death in Hinduism and Buddhism. Yama in Hinduism. Yama in Buddhism. The Brhadaranyaka ...
p. 2. "Death". Waikato Times. XLI (3315). 26 September 1893. p. 4. Retrieved 23 February 2014. "Local and General". The Star ( ... "Death". The Timaru Herald. LV (5743). 8 August 1893. p. 2. Retrieved 23 February 2014. "Marriages". The Star (5733). 28 ... "Deaths". The Press. LXVII (14051). 24 May 1911. p. 1. Retrieved 22 February 2014. Harper, Margaret. "Christchurch Street Names ...
"Death". Mataura Ensign. 6 December 1892. p. 4. Retrieved 31 January 2017. ...
"Death". Competition Science Vision. August 1998. p. 792. Miles, Dick (6 May 1968). "The Channel Is a Place to Suffer". Sports ...
Death.' to the C.H.A.O.S. Split album released on July 20, 2017 through Art of Propaganda. The album was dedicated to the ... There's no conformity involved as far as genres-black metal, death metal, whatever. I just write riffs that feel right to me. ... Though the band's style can be broadly categorized as blending elements of death metal or black metal, critics have noted the ... muddy blast-beat death/black metal succeeds and it's succeeded by abysmal doom metal passages." NPR Music compared the EP to ...
Mea'ole died a year later in 1963, leaving Tanumafili as the sole holder of the office until his death in 2007, aged 94. His ... death. The position is that of a ceremonial head of state, while actual power is held by the Prime Minister, whom the O le Ao o ...
Death? Get over it". SFX. Retrieved 2011-07-14. The New World on Tardis Data Core, an external wiki The New World - Script at ...
zimbabweournalists.com details of death Jan Raath, "Double cross turns tables on Mugabe militia", The Times, 24 October 2003, p ... Death." [1] On taking up his office, Dr Jokonya offered regular meetings with journalists to discuss their coverage. He told ... "Jokonya death: Family rules out foul play", Zimbabwe Herald, 26 June 2006. ...
How harsh his midnight cry! It seems to shriek, in mournful sounds, Death! Death! The Prince of the Air certainly causes them [ ... The funnel-shaped cloud deals death and destruction to all that come within its whirling, deadly grasp. When seeing the ...
Death. Unlucky years are different for men and women, in the old way of thinking, for men 25, 42, 61 are unlucky and 19, 33, 37 ...
dEatH. rOck N' roLL. , Garage Grrls , Jami Deadly". Horror Garage. Retrieved October 24, 2013. https://www.youtube.com/user/ ...
"Death". Taranaki Herald. 3 October 1882. p. 2. Retrieved 29 August 2015. "Cemetery search". New Plymouth District Council. ...
"Death of Mr John White". West Coast Times (2322). 6 September 1876. p. 2. Retrieved 8 March 2014. Scholefield 1950, p. 243. ... "Death". Grey River Argus. XXXVIII (6773). 2 June 1890. p. 2. Retrieved 8 March 2014. "Wellington News". The Star (6869). 3 June ... "Death of another Legislative Councillor". Ashburton Guardian. XII (2430). 2 June 1890. p. 2. Retrieved 8 March 2014. ... He was a member of the Legislative Council from 9 July 1872 until his death. Lahmann died on to 1 June 1890 at his residence in ...
"Death". The Nelson Evening Mail. XXIII (325). 24 December 1889. p. 2. Retrieved 21 June 2015. Sources Richardson, Lesley (1995 ...
"Death". DartMUD Helpfiles. Retrieved 2008-03-29. "Hexes". Dartmud Helpfiles. Retrieved 2008-03-29. "Text versus Graphics". Raph ... Permanent Death: DartMUD is targeted at hard-core mudders, people willing to risk permadeath - a common occurrence - in order ...
"Death". Colonist. XXXV (7404). 18 August 1892. p. 3. Retrieved 2 February 2016. "Secondary schools". Cyclopedia of New Zealand ... "Births, Marriages, and Deaths". Wellington Independent. XXI (2480). 14 February 1867. p. 4. Retrieved 2 February 2016. "Married ...
DEATH. LIARDET.- On the 21st March, at Vogeltown, W. F. Evelyn Liardet, aged 79 years, father of Mr. Hector and Sinclair ... "DEATH OF MR. JOHN EVELYN LIARDET". The Sydney Morning Herald. National Library of Australia. 30 October 1902. p. 7. Retrieved ...
"Death". The Press. III (294). 9 October 1863. p. 2. Retrieved 8 June 2016. Greenaway, Richard L. N. (June 2007). "Barbadoes ...
Death (Survivorship, Actions for Death, Death Certificate, Uniform Anatomical Gift Act, Living Wills); Decedents' Estates; ... Presumption of death or survivorship, see Death; Pretermitted children, see Wills; PRINCIPAL AND AGENT - See also Brokers, ... Wrongful death, see Death. Magrauth, Joseph Walker, ed. (1931). Sixty-Third Year, The Martindale-Hubbbell Law Directory (Annual ... Interstate Arbitration of Death Taxes; Interstate Compromise of Death Taxes; Interstate Family Support; Interstate Family ...
"Births, Marriages, and Deaths". Otago Daily Times (3300). 3 September 1872. p. 3. Retrieved 23 May 2012. "Deaths". Otago ... "Deaths". Otago Daily Times (11455). 21 June 1899. p. 4. Retrieved 22 May 2012. "Cemeteries search". Dunedin City Council. ... "Death". Otago Daily Times (3659). 27 October 1873. p. 2. Retrieved 22 May 2012. "Cemeteries search". Dunedin City Council. ... "Deaths". Otago Daily Times (2257). 30 April 1869. p. 2. Retrieved 22 May 2012. "Cemeteries search". Dunedin City Council. ...
At the time of his death he had been suffering from influenza and fever. Before his death he had been notified that the ... and his resulting distress may have contributed to his death. Because of the timing of his death, some people speculated that ... After Lim's death, many of his children left Burma, and his descendants now live in various Commonwealth countries, including ... After Lim's death, many stories circulated orally among the residents of Yangon concerning the sudden circumstances of his ...
"Death". Auckland Star. III (742). 31 May 1872. p. 2. Retrieved 30 December 2014. Jackson, William Keith (1972). The New Zealand ... His career culminated as a member of the New Zealand Legislative Council from 1866 until his death in 1872. Captain Peacocke's ... The headstone over their grave reads: "In death they were not divided". Swami, V. Narayan (27 January 2009). "Ooty Preserved : ... but his membership lapsed due to non-attendance and his final date of membership is the same as his death date. Isabella ...
"Death". The Timaru Herald. XXXII (1706). 10 March 1880. p. 2. Retrieved 25 August 2014. ...
Christ's passion and death Maranam jayicha veera ... (Hero, that won over death ...) - Resurrection. Yesu varum vegathil - ... The letter he sent to the assembly fellowship in Paravur four years prior to his death reflects the hunger in his heart for ... Samayamam rathathil njaan swerga yathra cheyyunnu ... (In the chariot of time I am on my homeward journey ...) - Death. His ...
Cases & Deaths * Cases and Deaths by State. * Daily and Total Trends. * State Trend Comparison. ...
This study looked at gallbladder cancer incidence and death rates in the United States. ... Gallbladder cancer is more common among women (1.4 cases and 0.7 deaths per 100,000 women) than men (0.8 cases and 0.5 deaths ... American Indian and Alaska Native people had the highest gallbladder cancer incidence and death rates (3.2 cases and 1.6 deaths ... CDC researchers used U.S. Cancer Statistics data to figure gallbladder cancer incidence (new cases) and death rates by sex, ...
Times of death and convulsions in the 24 hours prior to each death were identified during off-line visual inspection of records ... Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in intractable epilepsies, but physiological ... Sudden unexpected death in a mouse model of Dravet syndrome.. Kalume F1, Westenbroek RE, Cheah CS, Yu FH, Oakley JC, Scheuer T ... illustrating the seizure and bradycardia preceding death. Time of death was defined as the moment when the power of the EEG ...
17 The death certificate database includes all deaths in Ontario. Causes of death were determined from death certificates, ... Mean age at death was 39 years. Among women 18-44 years of age, the most common causes of death were HIV/AIDS and drug overdose ... 31, 1997, or, in the case of decedents, date of death.14,17 Mortality rates were calculated by dividing the number of deaths by ... Deaths in the study population were ascertained by comparing the database of shelter users with Ontario death certificate ...
I have done many studies and research on opioid deaths and what I found is very few opioid deaths are caused by prescription ... that accounts for 1,000X greater fatalities/deaths (and OD deaths) than ANY Physician-prescribed opiate regime EVER has -or ... Most opioid deaths are from illegal fentanyl opioid drugs. This is not fair to the millions of legitimate people in pain suffer ... Deaths from opioids have been rising sharply for years, and drug overdoses already kill more Americans under age 50 than ...
A fact sheet that describes the incidence and death rates for selected cancers among racial and ethnic groups living in the ... The lowest death rates for prostate cancer are found in Asian/Pacific Islander men. Incidence and death rates for prostate ... The highest death rate from cervical cancer is among African American/Black women. Incidence and death rates for cervical ... For all cancers combined, the death rate is 25 percent higher for African Americans/Blacks than for Whites. Incidence and death ...
SIDS is the leading cause of death among infants 1 month to 1 year old. Though SIDS remains unpredictable, you can help reduce ... Sudden infant death syndrome (SIDS) is the sudden and unexplained death of a baby younger than 1 year old. Most SIDS deaths are ... Most SIDS deaths happen in babies 2 to 4 months old, and cases rise during cold weather. Black and Native American infants are ... When considering which babies could be most at risk, no single thing is likely to cause a SIDS death. Rather, several risk ...
3: Alzheimers doesnt lead to death.. Sadly, its the sixth leading cause of death in the U.S. Most people live 8 to 10 years ...
... a death rate of 1 in 24,000 translates to 1.5 deaths per day (541 children annually); while a death rate of 1 in 500,000 ... Death rate is likely to be significantly higher from non-medicalized circumcisions performed at home, en masse, and/or under ... Estimated Number of Circumcision-Related Deaths. (based on 1994 world estimate of circumcised males: 647,701,200). 1,295 to ... male circumcisions performed, or the number of circumcision-related complications or deaths. ...
... When an U.S. citizen dies abroad, the Bureau of Consular Affairs assists the family and friends. The Bureau of ... For more information on the Consular Report of the Death of an American Abroad, and other services that a consular officer can ... Upon issuance of a local (foreign) death certificate, the nearest embassy or consulate may prepare a Consular Report of the ... citizen who dies abroad if the deceased has no legal representative or next-of-kin in the country where the death occurred, ...
The man, still walking down the highway, meets Death. The man decides to make Death the childs godfather saying that Death ... If Death stands at the persons head, that person is to be given the special herb found in the forest, and cured. But, if Death ... The next Sunday, Death becomes the childs godfather. When the boy comes of age, Death appears to him and leads him into the ... Death explains that the length of each candle shows how much longer a person has to live. When Death shows the physician his ...
Sudden death (athletes). Sports[edit]. *Sudden death (sport), a form of competition where play ends as soon as one competitor ... Sudden Infant Death Syndrome. This disambiguation page lists articles associated with the title Sudden death.. If an internal ... 1958 NFL Championship Game, nicknamed "Sudden Death" for its dramatic ending. Entertainment[edit]. *Sudden Death (1995 film), a ... Sudden cardiac death, natural death from cardiac causes. * ... Sudden Death or Sudden death may refer to:. * ...
It covers programmed cell death, cell death induced by toxic agents, differentiation and their relation to cell proliferation. ... Cell death and Differentiation provides an accessible source of up-to-date information for scientists and clinicians. ... Welcome to Cell Death & Differentiation Devoted to the cell biology, molecular biology and biochemistry of cell death and ... the latest web focus which highlights some of the latest research from China covered by the three journals in the Cell Death ...
... Collected by Mang Ali. WAMY Series on Islam World Assembly of Muslim Youth (WAMY). P.O.Box 10845. Riyadh 11443 ... "Until, when death comes to one of them, he says: O my Lord! Send me back (to life),- In order that I may work righteousness in ... Fifthly, Gods attributes of Justice and Mercy have no meaning if there is no life after death. Further Readings on Islam: *T. ... Such persons realize their folly only at the time of their death and wish to be given a further chance in the world but in vain ...
Death with Dignity. Please read about the the mission of the Death with Dignity National Center - support them if you can. All ... Digital Death. When you die you leave behind a lot of digital assets, as well as things that can/need to be accessed digitally ... Or in the cases of your family it will make dealing with their death less stressful - which is important when it will already ... No matter how old you are, you need to discuss death with your parents, your children (when they are older), your significant ...
Eternal Death is the second album of Crown of Thorns. It was originally released in 1997 and later re-issued under the bands ... "Death of God" - 10:08 (M. Olsfelt) Marcus Sunesson - Guitar Janne Saarenpää - Drums Magnus Olsfelt - Bass Guitar Johan ...
Death in Sanatorium B.J. Winslow - Death in Morgue Joan Farrell - Traci The New York Times DVD Talk Death Tunnel on IMDb Death ... Death Tunnel is a 2005 horror movie filmed at the Waverly Hills Sanatorium. It stars Steffany Huckaby, Annie Burgstede, Kristin ...
Death anxiety may refer to: Existential angst The Sickness Unto Death & The Concept of Anxiety, psychological works on angst by ... Death Anxiety (song) by the group Bleeding Through. ... Søren Kierkegaard Death anxiety (psychology) Terror management ...
Ecological death is the inability of an organism to function in an ecological context, leading to death. This term can be used ... it can also lead to ecological death. An effect caused by DDT is shell thinning in bird eggs, leading to the death of the chick ... If this alteration does not directly cause death, but impacts the behavior or physiology of the organism, it can also lead to ... This is an example of a physiological sublethal effect leading to ecological death. Scott, G.R., and K.A. Sloman. 2004. The ...
Texas jurys quick death sentence for John William King, which the WP puts on page 3, while the LAT runs it on page 28. The... ... USAT leads with a Jasper, Texas jurys quick death sentence for John William King, which the WP puts on page 3, while the LAT ... Also, the papers dont mention it, but this story should give pause to anyone who thinks the death penalty is a deterrent. The ... The paper goes on to report that since the Supreme Court reinstated the death penalty in 1976, nationwide eight whites have ...
the death) The collapse or end of something. England scored a goal at the death to even the score at one all. death of the ... death from natural causes), mate whawhati tata (sudden death), mate koeo (natural death), hautapu (by violence) ... death (countable and uncountable, plural deaths). *The cessation of life and all associated processes; the end of an organisms ... often capitalized) The personification of death as a hooded figure with a scythe; the Grim Reaper. When death walked in, a ...
I do not believe it is possible to know how much of his misery at this time was due to malaria, to medicines, or to the death ... David Brown: People with MEN 2B are definitely prone to illness and early death, which is why Lincolns longevity (he died at ... Arlington, Va.: Are individuals with this condition more prone to illness and early death? I notice in pictures of Lincolns ... The first was in connection with the death of Lincolns near-fiancee, Ann Rutledge. (This is a hugely controversial point with ...
... Doom and Doom2 Wads Heretic Wads HeXen Wads ...
Death Note (2017) TV-MA , 1h 41min , Action, Adventure, Crime , 25 August 2017 (USA) ... The closing credits are written in the same style as the Death Note instructions. See more » ...
The crude mortality rate or crude death rate is defined as the ratio of the number of deaths during the year to the average ... The infant mortality rate is defined as the ratio of the number of deaths of children under one year of age to the number of ... Mortality is the number of deaths for a given area during a given period. Infant mortality is the mortality of live-born ... A death, according to the United Nations definition, is the permanent disappearance of all vital functions without possibility ...
  • The paper goes on to report that since the Supreme Court reinstated the death penalty in 1976, nationwide eight whites have been executed for killing blacks while 123 blacks have been put to death for killing whites. (slate.com)
  • We report mortality rates and causes of death in a cohort of women who used homeless shelters in Toronto. (cmaj.ca)
  • Mortality is the number of deaths for a given area during a given period. (europa.eu)
  • The mortality rate or death rate is the mortality expressed as a proportion of the population. (europa.eu)
  • Maternal death, or maternal mortality: defined by the World Health Organization (WHO) as "the death of a woman while pregnant or within 42 days of termination of pregnancy, irrespective of the duration and site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes. (wikimedia.org)
  • Data about deaths was available through the National Health Service Central Register mortality register. (www.nhs.uk)
  • All-cause mortality and deaths from cardiovascular disease and cancer were recorded from the start of the participants' three-year exposure period until September 30 2004. (www.nhs.uk)
  • A record cannot be identified as available prior to purchase because under State statute (IC 16-37-1-11 and IC 37-1-11.5), the fee associated with a death certificate is for the ISDH Vital Records office to search the records to determine if a record is on file. (in.gov)
  • A cohort of 1981 women not accompanied by dependent children who used homeless shelters in Toronto in 1995 was observed for death over a mean of 2.6 years. (cmaj.ca)
  • Nationwide, a study by Columbia University School of Law Professor James Liebman found that 68 percent of death penalty appeals were successful between 1973 and 1995. (law.com)
  • Nel 1995 anche il Live After Death , come tutti gli altri album pubblicati dagli Iron Maiden fino a quel momento, venne ripubblicato in versione doppio CD con le b-side dei singoli inseriti nel secondo CD (per la precisione i brani Losfer Words (Big 'Orra) , Sanctuary e Murders in the Rue Morgue ). (wikipedia.org)
  • Gallbladder cancer is more common among women (1.4 cases and 0.7 deaths per 100,000 women) than men (0.8 cases and 0.5 deaths per 100,000 men). (cdc.gov)
  • American Indian and Alaska Native people had the highest gallbladder cancer incidence and death rates (3.2 cases and 1.6 deaths per 100,000 people). (cdc.gov)
  • These statistics are most often reported as the numbers of new cases of invasive cancer and cancer deaths per year per 100,000 persons in the U.S. population. (cancer.gov)
  • When the statistics focus on cancer incidence and death in a single gender for example, on female breast cancer or male prostate cancer the numbers are per 100,000 persons of that gender. (cancer.gov)
  • The combat-related death gratuity of $100,000 took effect May 11 when the president signed the Emergency Supplemental Wartime Appropriations Act (Public Law 109-13). (military.com)
  • Because the wartime supplemental bill expires on Sept. 30, provisions to make permanent the combat-related death gratuity of $100,000 and SGLI coverage of $400,000 are included in fiscal 2006 defense authorization bills moving through Congress. (military.com)
  • But Bill Vance, Democratic candidate for the Texas Court of Criminal Appeals - who says he favors the death penalty for those who deserve it - contends the appeals system for death row inmates isn't working properly and says appellants aren't getting a fair shake. (law.com)
  • The country last executed prisoners exactly a year earlier, when the conservative Liberal Democratic Party still ruled the country, putting to death three inmates including one Chinese national, also for multiple murder. (smh.com.au)
  • The Connecticut Supreme Court held in a 4-3 decision issued Aug. 13, that the execution of inmates who committed capital felonies before the state abolished the death penalty in 2012 would violate Connecticut's constitutional prohibition against cruel and unusual punishment. (ncsl.org)
  • The law was not applied retroactively, which meant that the 11 inmates were left on death row. (ncsl.org)
  • And Texas, a single state, accounts for nearly a third of all federal death-row inmates. (thenation.com)
  • Furman v. Georgia (1972): The Supreme Court declared the death penalty unconstitutional, as cruel and unusual punishment in violation of the Eight Amendment, and finding that the administration of the ultimate punishment was arbitrary and capricious. (aclu.org)
  • The reformers in recent years also persuaded the authorities to require Supreme Court approval for all death sentences and to make torture inadmissible in capital cases. (cnbc.com)
  • Since 1973, 138 death-row prisoners have been released because they were innocent. (aclu.org)
  • Japan has often been criticised internationally for its use of the death penalty and the fact that death row prisoners and their families are not told about the execution date in advance. (smh.com.au)
  • To write a letter on behalf of Juan Raul Garza, as well as the other prisoners currently on state and federal death row, visit our Death Row Roll Call . (thenation.com)
  • In the July-August 2003 Atlantic Monthly , Alan Berlow wrote a long, carefully documented article, "The Texas Clemency Memos," which told of the role of Gonzales, then legal counsel to Texas governor George W. Bush, in deciding the fate of prisoners on death row, including the mentally retarded. (villagevoice.com)
  • Defendants who kill white people are far more likely to get the death penalty than those who kill black people. (aclu.org)
  • As Election Day nears, a nationwide report on appellate review procedures for capital murder defendants roundly criticizes the death penalty appeals process in Texas, calling it a dysfunctional assembly line. (law.com)
  • Garza's case raised these questions in a particularly direct way, because the study found that the federal death penalty is disproportionately sought and obtained against black and Hispanic defendants, and disproportionately meted out in a handful of states, Texas the leader among them. (thenation.com)
  • Federal prosecutors are twice as likely to reach plea agreements avoiding death sentences with white than with black and Hispanic capital defendants. (thenation.com)
  • Ashcroft stresses that of all federal cases that could have been tried as capital cases, the Attorney General actually authorized the death penalty more often against white defendants than minority defendants. (thenation.com)
  • Providing legal defense or legal aid to the defendants in death penalty cases, especially in cases that are wrongly sentenced, that involve the use of torture or that have procedural defects, or that in which the defendant suffers from mental illnesses. (archive.org)
  • The bigger death gratuity is retroactive to Oct. 7, 2001, the start of Operation Enduring Freedom in Afghanistan. (military.com)
  • Death records in the ISDH Vital Records office begin with 1900. (in.gov)
  • Prior to 1900, records of death are filed only with the local health department in the county where the death actually occurred. (in.gov)
  • For deaths occurring from 1900 to 1917, the city and/or county of death is required in order to locate the record. (in.gov)
  • Deaths from opioids have been rising sharply for years , and drug overdoses already kill more Americans under age 50 than anything else. (statnews.com)
  • Deaths involving fentanyl and other synthetic opioids have surged from around 3,000 in 2013 to more than 30,000 in 2018. (rand.org)
  • For U.S. Citizens who died abroad, please visit the U.S. Department of State's Death Abroad webpage. (in.gov)
  • Maryland State's Attorney Marilyn Mosby announces charges against Baltimore police officers in connection with the death of Freddie Gray, in Baltimore, May 1, 2015. (voanews.com)
  • On April 25, 2012, Connecticut Governor Dannel Malloy signed Senate Bill 280 (2012) , ending the state's death penalty. (ncsl.org)
  • We studied the mechanism of premature death in Scn1a heterozygous KO mice and conditional brain- and cardiac-specific KOs. (nih.gov)
  • Authorities amended Wood's death certificate on Aug. 1, 2012 to reflect some of the lingering questions about how the actress died in the waters off Catalina Island in November 1981. (yahoo.com)
  • Napalm Death - angielska grupa muzyczna powstała w 1981 roku w Meriden w pobliżu Coventry . (wikipedia.org)
  • Numerous polls repeatedly show that Texans favor the death penalty, even though they fear that innocent people may be put to death. (law.com)
  • However, with the mounting of casualty sensitivity, the state gradually restructured what Levy calls its "death hierarchy" to favor privileged soldiers over soldiers drawn from lower classes and civilians, and later to place enemy civilians at the bottom of the hierarchy by the use of heavy firepower. (jhu.edu)
  • Three days after Safra's death, Daniel Serdet, the attorney general and chief prosecutor of Monaco, announced that a male nurse named Ted Maher, from Stormville, New York, had confessed to setting the blaze that killed his employer in order to win favor with the banker. (vanityfair.com)
  • Homeless people are at high risk for illness and have higher death rates than the general population. (cmaj.ca)
  • 15 A study of people using homeless shelters in New York found age-adjusted death rates 2 to 3 times higher than those in the city's general population. (cmaj.ca)
  • All the prophets of God called their people to worship God and to believe in life after death. (angelfire.com)
  • We also know that these prophets of God were greatly opposed by their people, mainly on the issue of life after death as their people thought it impossible. (angelfire.com)
  • That is why all the prophets of God while calling people to believe in God and life after death, appeal to the aesthetic, moral and rational consciousness of man. (angelfire.com)
  • Sicilian authorities hastily ordered the fleet of "death ships" out of the harbor, but it was too late: Over the next five years, the Black Death would kill more than 20 million people in Europe - almost one-third of the continent's population. (history.com)
  • Because they did not understand the biology of the disease, many people believed that the Black Death was a kind of divine punishment - retribution for sins against God such as greed, blasphemy, heresy, fornication and worldliness. (history.com)
  • The Texas Civil Rights Project reports that 445 people were on Texas' death row in September. (law.com)
  • One classified ad director argued to Chatterbox that the switch from news obits to paid death notices levelled the playing field between people perceived to be newsworthy and people who were not. (slate.com)
  • The collective experience of caregivers and researchers suggests that many people pass from life to death without another person at their side. (encyclopedia.com)
  • The latest hangings left 107 people on death row in Japan. (smh.com.au)
  • The amendment is the latest in a number of reforms to the death penalty pushed for by Chinese legal scholars who have complained that many people guilty of trivial crimes or unfairly tried have been executed. (cnbc.com)
  • Chinese legal experts said in practice the death penalty has seldom been used in recent years to punish people who committed these crimes and the draft amendment was largely intended to reflect the current reality. (cnbc.com)
  • In 1918, the popular religious writer Winifred Kirkland described a change in American life: people were preoccupied with death as never before. (jhu.edu)
  • In short, this is the notion that people can either draw on their own psychological resources (e. g ., solidified belief systems, relationships) to cope with thinking about death or, if that is not sustainable, cope with thoughts of death by avoiding self-awareness. (psychologytoday.com)
  • The results indicated that people with low self-esteem were less likely to think about themselves, and to write about themselves, after thinking about death versus a variety of other topics (e.g., pain, failure). (psychologytoday.com)
  • Other studies consistent with this line of reasoning show that - after a short delay of minutes - people with low self-esteem will have more negative mood when thinking about death. (psychologytoday.com)
  • Studies also show that these effects are reduced for people with low self-esteem if they are provided with "evidence" of life after death (that is, they read near-death experience accounts where people are convinced that there is an afterlife) or if you provide them with evidence that science is enabling people to live longer. (psychologytoday.com)
  • Sick leave 'link to early death'" is the headline on the BBC news website, suggesting that people who have "long spells of sick leave for psychiatric reasons" are twice as likely to die from cancer as healthier employees. (www.nhs.uk)
  • Although it suggests that there was a 2.5-fold increase in likelihood of cancer death with absence for 'psychiatric' reasons, the actual number of people dying in this category was very small. (www.nhs.uk)
  • It also requires us to start working when most of the people in the society still cannot accept the idea of abolishing death penalty. (archive.org)
  • Adds Edward McCaffrey, a professor at the University of Southern California who opposes the tax, "They've got good rhetoric, a good issue, and good timing--to most people, death seems like the wrong time to tax. (prospect.org)
  • Players will be able to tell us any kind of feedback and ideas through the Steam Forums, the official Death Trash Discord, Twitter, and Facebook. (steampowered.com)
  • How one decides to define the moment of death also depends on one's willingness to consider rigor mortis and other physiological processes that continue for some time afterward. (encyclopedia.com)
  • This past December, President Clinton put off Garza's execution date because a Justice Department study had raised serious questions about racial, ethnic and geographical disparities in the administration of the federal death penalty. (thenation.com)
  • Ashcroft issued a supplementary report, but it contained no new relevant information and failed to undertake the analysis required to determine whether the federal death-penalty disparities were attributable to bias. (thenation.com)
  • He cites the often-criticized case of Calvin Burdine, convicted and sentenced to death in Harris County for a 1983 robbery and murder. (law.com)
  • Beets was convicted of capital murder in the 1983 death of her fifth husband, retired Dallas fire captain Jimmy Don Beets. (mysanantonio.com)
  • Thanatology (from Greek thanatos, "death") as a professional discipline gathered momentum following the publication of several subject-related books including The Meaning of Death (1959), edited by Herman Feifel, and The Psychology of Death (1972) by Robert Kastenbaum and Ruth Aisenberg. (britannica.com)
  • Although cancer deaths have declined for both Whites and African Americans/Blacks living in the United States, African Americans/Blacks continue to suffer the greatest burden for each of the most common types of cancer. (cancer.gov)
  • At another occasion the Quran very clearly says that the disbelievers have no sound basis for their denial of life after death. (angelfire.com)
  • Death then warns the physician that if he was to ever trick Death again, he will take the physician's life. (wikipedia.org)
  • As the physician falls, he hears Death whisper quietly "You once looked for the most righteous one to be the godfather of your child, but at the Bed of Death you betrayed that and instead grasped for the life of another. (wikipedia.org)
  • The question whether there is a life after death does not fall under the jurisdiction of science as science is concerned only with classification and analysis of sense data. (angelfire.com)
  • Moreover, man has been busy with scientific enquiries and research, in the modern sense of the term, only for the last few centuries, while he has been familiar with the concept of life after death since times immemorial. (angelfire.com)
  • They laid so much emphasis on the belief in life after death that even a slight doubt in it meant denying God and made all other beliefs meaningless. (angelfire.com)
  • The very fact that all the prophets of God have dealt with this metaphysical question of life after death so confidently and so uniformly - the gap between their ages being thousands of years - goes to prove that the source of their knowledge of life after death as proclaimed by them all, was the same, i.e. (angelfire.com)
  • Not so, as perceptual experience of life after death is impossible. (angelfire.com)
  • The explanation that the Quran gives about the necessity of life after death is what moral consciousness of man demands. (angelfire.com)
  • Actually if there is no life after death, the very belief in God becomes irrelevant or even if one believes in God, that would be an unjust and indifferent God: having once created man not concerned with his fate. (angelfire.com)
  • If possible have some small life insurance to cover death related expenses. (google.com)
  • Seeing him waver, his wife, who was resolved to be with him in death as in life, took the dagger from his hand, plunged it into her own breast, and with her last strength held it out to him, gasping out, "It is not painful, my Pætus. (upenn.edu)
  • The most comprehensive death penalty study in the country found that the death penalty cost North Carolina $2.16 million more per execution over the costs of sentencing murderers to life imprisonment. (aclu.org)
  • NPR coverage of Erasing Death: The Science That Is Rewriting the Boundaries Between Life and Death by Sam, M.D., Ph.D. Parnia and Josh Young. (npr.org)
  • Circle of death snuffs out the life force of living creatures, killing them instantly. (google.com)
  • Death Sentence is also a manifesto, the first shots, Watson hopes, in a campaign everyone can join to bring the language back to life. (theage.com.au)
  • A year after Litvinenko's death, Berezovsky said Scotland Yard had warned him about a plot on his life , but British police never confirmed his claim. (yahoo.com)
  • The most common assumption in Western society is that life gives way to death in a "razor-thin" moment. (encyclopedia.com)
  • A nurse could detect the cessation of vital functions if the patient is on life support, and this might be considered the moment of death. (encyclopedia.com)
  • Thanatology also examines attitudes toward death, the meaning and behaviours of bereavement and grief, and the moral and ethical questions of euthanasia , organ transplants, and life support. (britannica.com)
  • In spite of the recent push toward the death penalty, I do not believe it is mankind's privilege to decide on the life of another human being. (latimes.com)
  • Ecological death may be caused by sublethal toxicological effects that can be behavioral, physiological, biochemical, or histological. (wikipedia.org)
  • This is an example of physiological and biochemical sublethal effects leading to ecological death of the chick. (wikipedia.org)
  • The moment of death has become a more problematic concept with the changing definitions of death and the technological advances that can keep basic physiological systems going even if there is no discernible mental functioning. (encyclopedia.com)
  • As the Gaza offensive of 2009 demonstrates, this new death hierarchy has opened Israel to global criticism. (jhu.edu)
  • Prosecuting a death penalty case is extremely expensive for a state and drains money that could be used for education and social programs. (aclu.org)
  • We're planning to keep Death Trash in Early Access for about a year. (steampowered.com)
  • Russian oligarch Boris Berezovsky was not killed by chemical or radioactive material, British police said today, but still calling the 67-year-old's death unexplained. (yahoo.com)
  • Six Baltimore police officers were arrested and posted bail Friday, after the chief prosecutor for the eastern U.S. city of Baltimore announced criminal charges in the death of a 25-year-old man earlier this month. (voanews.com)
  • The official explanation for the death of multibillionaire banker Edmond Safra, who was asphyxiated a year ago in a locked bathroom of his Monte Carlo penthouse, is that one of Safra's nurses set the fire in order to heroically rescue his employer. (vanityfair.com)
  • The root of the problem is that there simply is no fair and objective way to isolate, from among the approximately 20,000 homicides that take place each year, the 100 or so that will lead to the ultimate punishment of death. (thenation.com)
  • Two-thirds of cases and deaths occurred among women. (cdc.gov)
  • Or in the cases of your family it will make dealing with their death less stressful - which is important when it will already be such a stressful event on its own. (google.com)
  • In its review of death penalty expenses, the State of Kansas concluded that capital cases are 70 percent more expensive than comparable non-death penalty cases, including the costs of incarceration. (aclu.org)
  • We have covered extensively the death row cases of Troy Davis and Mumia Abu-Jamal. (democracynow.org)
  • Ashcroft's report also emphasizes the many procedural safeguards the federal government has put in place to ensure that race does not affect the imposition of death, including instructions to jurors, appointment of competent defense counsel and centralized review in the Justice Department of all federal death-penalty cases. (thenation.com)
  • CADP aims at abolishing death penalty in China, through legal aid, discussion conferences, citizen education, documentary and movie-screening, most importantly, we will do our independent researches through collecting and analyzing specific death penalty cases in China and give annual reports on Death Penalty in China. (archive.org)
  • In addition to that, CADP will also take an active part in correcting wrongly-sentenced death penalty cases through our legal aid program. (archive.org)
  • Lin Ruiqiang case in Guangdong Provinces and many other obviously wrongly-sentenced death penalty cases. (archive.org)
  • In the next three years, we can, by means of legal aid to some typical wrong death penalty cases and by educating the public, promote the idea of anti-death-penalty, and promote more prudence in the death sentencing, and achieving the goal of creating a ground for the society to reflect upon the use of death penalty, and nearly no death penalty in non-violent cases. (archive.org)
  • It has been a poor relation to another, more exciting type of cell death called "apoptosis", or programmed cell death. (newscientist.com)
  • Larger declines were recorded in relation to deaths from ischaemic heart disease, where death rates fell by 30.3 % for men and 34.3 % for women, while even greater reductions were recorded for deaths from transport accidents where rates fell by 43.3 % for men and 44.3 % for women. (europa.eu)
  • Arnaud Wisman, a lecturer in psychology at the University of Kent, proposed the idea of ' using or losing' the self in relation to thinking about death. (psychologytoday.com)
  • Amid the death penalty debate - much of it centered on Gov. George W. Bush's run for president - there are increasing complaints about the appeals process for those who are sentenced to die in Texas. (law.com)
  • Media Watch reports on media coverage of death threats on climate scientists: One news outlet comes out of it, in our opinion, almost unscathed: Fairfax Media's The Canberra Times. (scienceblogs.com)
  • This doesn't come up at big-city newspapers, because there's no way to run news stories about more than a tiny proportion of the local deaths. (slate.com)
  • But that argument would have been more compelling had the trend toward paid death notices occurred spontaneously, as opposed to being forced on consumers by the shrinking news obit hole. (slate.com)
  • Reports of mass graves, torched casinos, and mutilated bodies have become so commonplace that there are days when the Google Mexico news feed is nothing but a death scroll. (prospect.org)
  • News of Berezovsky's death sparked speculation that he might have been killed like ex-KGB agent Alexander Litvinenko, who died in 2006 after he was poisoned with polonium-210 while drinking tea at a London meeting. (yahoo.com)
  • For the latest on Whitney Houston's death, see our music news page. (telegraph.co.uk)
  • Japan's justice minister, a foe of capital punishment, has announced a review of the death penalty after witnessing the first executions since her centre-left government took power in 2009. (smh.com.au)
  • We are acutely aware of the level of interest into his death and are focused on conducting a thorough investigation as we would with any unexplained death. (yahoo.com)
  • The group called on the National Transitional Council (NTC), Libya's new leadership, to conduct an 'immediate and transparent' investigation into the deaths in Sirte. (rferl.org)