AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Gingival NeoplasmsGingivitisEpithelial AttachmentGingival HyperplasiaGingival RecessionGingival OvergrowthFibromatosis, GingivalGingivoplastyGingivectomyGingival HypertrophyPeriodontal ProsthesisMouth MucosaPeriodontitisOral UlcerGingival Crevicular FluidPeriodontal IndexAlveolar ProcessPalate, HardOral Surgical ProceduresCuspidGingival HemorrhagePeriodonticsMaxillary NeoplasmsRoot PlaningPhotography, DentalPeriodontal PocketConnective TissueMaxillaTongue, FissuredMandibular NeoplasmsChronic PeriodontitisFibroma, OssifyingLip DiseasesTooth MovementPeriodontal DiseasesOdontogenic Cyst, CalcifyingMouth DiseasesTooth EruptionPeriodontal Attachment LossPigmentation DisordersMandibleMouth NeoplasmsAggressive PeriodontitisLipDental RecordsPeriodontiumAmeloblastomaDental Plaque IndexMouth FloorColorOrthodontic AppliancesTooth RootMouthPrevotella intermediaZirconiumPorphyromonas gingivalisMolarDental PlaqueFibroblastsColorimetryEpitheliumImmunohistochemistryKeratinsCarcinoma, Squamous CellGingivaCollagenDogsFollow-Up StudiesTime FactorsRNA, MessengerTreatment Outcome
Gingival Neoplasms
Gingivitis
Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
Epithelial Attachment
A wedge-shaped collar of epithelial cells which form the attachment of the gingiva to the tooth surface at the base of the gingival crevice.
Gingival Hyperplasia
Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)
Gingival Recession
Exposure of the root surface when the edge of the gum (GINGIVA) moves apically away from the crown of the tooth. This is common with advancing age, vigorous tooth brushing, diseases, or tissue loss of the gingiva, the PERIODONTAL LIGAMENT and the supporting bone (ALVEOLAR PROCESS).
Gingival Overgrowth
Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)
Fibromatosis, Gingival
Generalized or localized diffuse fibrous overgrowth of the gingival tissue, usually transmitted as an autosomal dominant trait, but some cases are idiopathic and others produced by drugs. The enlarged gingiva is pink, firm, and has a leather-like consistency with a minutely pebbled surface and in severe cases the teeth are almost completely covered and the enlargement projects into the oral vestibule. (Dorland, 28th ed)
Gingivoplasty
Surgical reshaping of the gingivae and papillae for correction of deformities (particularly enlargements) and to provide the gingivae with a normal and functional form, the incision creating an external bevel. (Dorland, 28th ed)
Gingivectomy
Surgical excision of the gingiva at the level of its attachment, thus creating new marginal gingiva. This procedure is used to eliminate gingival or periodontal pockets or to provide an approach for extensive surgical interventions, and to gain access necessary to remove calculus within the pocket. (Dorland, 28th ed)
Gingival Hypertrophy
Abnormal enlargement or overgrowth of the gingivae brought about by enlargement of existing cells.
Periodontal Prosthesis
Any restorative and replacement device that is used as a therapeutic aid in the treatment of periodontal disease. It is an adjunct to other forms of periodontal therapy and does not cure periodontal disease by itself. (Boucher's Clinical Dental Terminology, 3d ed)
Mouth Mucosa
Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
Periodontitis
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
Oral Ulcer
A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842)
Gingival Crevicular Fluid
A fluid occurring in minute amounts in the gingival crevice, believed by some authorities to be an inflammatory exudate and by others to cleanse material from the crevice, containing sticky plasma proteins which improve adhesions of the epithelial attachment, have antimicrobial properties, and exert antibody activity. (From Jablonski, Illustrated Dictionary of Dentistry, 1982)
Periodontal Index
A numerical rating scale for classifying the periodontal status of a person or population with a single figure which takes into consideration prevalence as well as severity of the condition. It is based upon probe measurement of periodontal pockets and on gingival tissue status.
Alveolar Process
The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.
Palate, Hard
The anteriorly located rigid section of the PALATE.
Oral Surgical Procedures
Surgical procedures used to treat disease, injuries, and defects of the oral and maxillofacial region.
Cuspid
The third tooth to the left and to the right of the midline of either jaw, situated between the second INCISOR and the premolar teeth (BICUSPID). (Jablonski, Dictionary of Dentistry, 1992, p817)
Gingival Hemorrhage
The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY.
Periodontics
A dental specialty concerned with the histology, physiology, and pathology of the tissues that support, attach, and surround the teeth, and of the treatment and prevention of disease affecting these tissues.
Maxillary Neoplasms
Cancer or tumors of the MAXILLA or upper jaw.
Root Planing
A procedure for smoothing of the roughened root surface or cementum of a tooth after subgingival curettage or scaling, as part of periodontal therapy.
Photography, Dental
Photographic techniques used in ORTHODONTICS; DENTAL ESTHETICS; and patient education.
Periodontal Pocket
An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.
Connective Tissue
Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.
Maxilla
One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.
Tongue, Fissured
Mandibular Neoplasms
Tumors or cancer of the MANDIBLE.
Chronic Periodontitis
Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.
Fibroma, Ossifying
A benign central bone tumor, usually of the jaws (especially the mandible), composed of fibrous connective tissue within which bone is formed.
Lip Diseases
Tooth Movement
Orthodontic techniques used to correct the malposition of a single tooth.
Periodontal Diseases
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Odontogenic Cyst, Calcifying
A mixed radiolucent-radiopaque lesion of the jaws with features of both a cyst and a solid neoplasm. It is characterized microscopically by an epithelial lining showing a palisaded layer of columnar basal cells, presence of ghost cell keratinization, dentinoid, and calcification. (Stedman, 25th ed)
Mouth Diseases
Tooth Eruption
The emergence of a tooth from within its follicle in the ALVEOLAR PROCESS of the MAXILLA or MANDIBLE into the ORAL CAVITY. (Boucher's Clinical Dental Terminology, 4th ed)
Periodontal Attachment Loss
Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.
Pigmentation Disorders
Mandible
The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.
Mouth Neoplasms
Tumors or cancer of the MOUTH.
Aggressive Periodontitis
Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
Lip
Either of the two fleshy, full-blooded margins of the mouth.
Dental Records
Data collected during dental examination for the purpose of study, diagnosis, or treatment planning.
Periodontium
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Ameloblastoma
An immature epithelial tumor of the JAW originating from the epithelial rests of Malassez or from other epithelial remnants of the ENAMEL from the developmental period. It is a slowly growing tumor, usually benign, but displays a marked propensity for invasive growth.
Dental Plaque Index
An index which scores the degree of dental plaque accumulation.
Mouth Floor
Color
The visually perceived property of objects created by absorption or reflection of specific wavelengths of light.
Orthodontic Appliances
Devices used for influencing tooth position. Orthodontic appliances may be classified as fixed or removable, active or retaining, and intraoral or extraoral. (Boucher's Clinical Dental Terminology, 4th ed, p19)
Tooth Root
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
Mouth
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
Prevotella intermedia
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth.
Zirconium
Zirconium. A rather rare metallic element, atomic number 40, atomic weight 91.22, symbol Zr. (From Dorland, 28th ed)
Porphyromonas gingivalis
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.
Molar
The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)
Dental Plaque
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
Fibroblasts
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
Colorimetry
Any technique by which an unknown color is evaluated in terms of standard colors. The technique may be visual, photoelectric, or indirect by means of spectrophotometry. It is used in chemistry and physics. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Epithelium
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
Immunohistochemistry
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Keratins
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Carcinoma, Squamous Cell
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
Gingiva
Oral tissue surrounding and attached to TEETH.
Collagen
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
Dogs
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Follow-Up Studies
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Time Factors
Elements of limited time intervals, contributing to particular results or situations.
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Treatment Outcome
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Treponema denticola outer membrane enhances the phagocytosis of collagen-coated beads by gingival fibroblasts. (1/958)

Human gingival fibroblasts (HGFs) degrade collagen fibrils in physiological processes by phagocytosis. Since Treponema denticola outer membrane (OM) extract perturbs actin filaments, important structures in phagocytosis, we determined whether the OM affects collagen phagocytosis in vitro by HGFs. Phagocytosis was measured by flow cytometric assessment of internalized collagen-coated fluorescent latex beads. Confluent HGFs pretreated with T. denticola ATCC 35405 OM exhibited an increase in the percentage of collagen phagocytic cells (phagocytosis index [PI]) and in the number of beads per phagocytosing cell (phagocytic capacity [PC]) compared with untreated controls. The enhancement was swift (within 15 min) and was still evident after 1 day. PI and PC of HGFs for bovine serum albumin (BSA)-coated beads were also increased, indicating a global increase in phagocytic processes. These results contrasted those for control OM from Veillonella atypica ATCC 17744, which decreased phagocytosis. The T. denticola OM-induced increase in bead uptake was eliminated by heating the OM and by depolymerization of actin filaments by cytochalasin D treatment of HGFs. Fluid-phase accumulation of lucifer yellow was enhanced in a saturable, concentration-dependent, transient manner by the T. denticola OM. Our findings were not due to HGF detachment or cytotoxicity in response to the T. denticola OM treatment since the HGFs exhibited minimal detachment from the substratum; they did not take up propidium iodide; and there was no change in their size, granularity, or content of sub-G1 DNA. We conclude that a heat-sensitive component(s) in T. denticola OM extract stimulates collagen phagocytosis and other endocytic processes such as nonspecific phagocytosis and pinocytosis by HGFs.  (+info)

Lipoteichoic acid acts as an antagonist and an agonist of lipopolysaccharide on human gingival fibroblasts and monocytes in a CD14-dependent manner. (2/958)

CD14 has been implicated as a receptor of lipoteichoic acid (LTA) and other bacterial components as well as lipopolysaccharide (LPS). Since the structures of LTAs from various gram-positive bacteria are heterogeneous, we analyzed the effects of LTAs on the secretion of interleukin-8 (IL-8) by high- and low-CD14-expressing (CD14(high) and CD14(low)) human gingival fibroblasts (HGF). While Bacillus subtilis LTA had an IL-8-inducing effect on CD14(high) HGF which was considerably weaker than that of LPS, Streptococcus sanguis and Streptococcus mutans LTAs had practically no effect on the cells. B. subtilis LTA had only a weak effect on CD14(low) HGF, as did LPS. S. sanguis and S. mutans LTAs at a 1,000-fold excess each completely inhibited the IL-8-inducing activities of both LPS and a synthetic lipid A on CD14(high) HGF. The effect of LPS was also inhibited by the presence of an LPS antagonist, synthetic lipid A precursor IVA (LA-14-PP), with a 100-fold higher potency than S. sanguis and S. mutans LTAs and by anti-CD14 monoclonal antibody (MAb). S. sanguis and S. mutans LTAs, LA-14-PP, and anti-CD14 MAb had no significant effect on phorbol myristate acetate-stimulated IL-8 secretion by HGF. These LTAs also inhibited the IL-8-inducing activity of B. subtilis LTA on CD14(high) HGF, as did LA-14-PP and anti-CD14 MAb. The antagonistic and agonistic functions of LTAs were also observed with human monocytes. Binding of fluorolabeled LPS to human monocytes was inhibited by S. sanguis LTA, although the inhibition was 100 times weaker than that of LPS itself, and anti-CD14 MAb inhibited fluorolabeled LPS and S. sanguis LTA binding. Binding of LTAs to CD14 was also observed with nondenaturing polyacrylamide gel electrophoresis. These results indicate that LTAs act as antagonists or agonists via a CD14-dependent mechanism, probably due to the heterogeneous structure of LTAs, and that an antagonistic LTA might be a useful agent for suppressing the periodontal disease caused by gram-negative bacteria.  (+info)

Targeted disruption of fibronectin-integrin interactions in human gingival fibroblasts by the RI protease of Porphyromonas gingivalis W50. (3/958)

Cell surface integrins mediate interactions between cells and their extracellular matrix and are frequently exploited by a range of bacterial pathogens to facilitate adherence and/or invasion. In this study we examined the effects of Porphyromonas gingivalis proteases on human gingival fibroblast (HGF) integrins and their fibronectin matrix. Culture supernatant from the virulent strain W50 caused considerably greater loss of the beta1 integrin subunit from HGF in vitro than did that of the beige-pigmented strain W50/BE1. Prior treatment of the W50 culture supernatant with the protease inhibitor Nalpha-p-tosyl-L-lysine chloromethyl ketone (TLCK) blocked its effects on cultured cells, indicating that this process is proteolytically mediated. Purified arginine-specific proteases from P. gingivalis W50 were able to mimic the effects of the whole-culture supernatant on loss of beta1 integrin expression. However purified RI, an alpha/beta heterodimer in which the catalytic chain is associated with an adhesin chain, was 12 times more active than RIA, the catalytic monomer, in causing loss of the alpha5beta1 integrin (fibronectin receptor) from HGF. No effect was observed on the alphaVbeta3 integrin (vitronectin receptor). The sites of action of RI and RIA were investigated in cells exposed to proteases pretreated with TLCK to inactivate the catalytic component. Use of both monoclonal antibody 1A1, which recognizes only the adhesin chain of RI, and a rabbit antibody against P. gingivalis whole cells indicated localization of RI on the fibroblasts in a clear, linear pattern typical of that seen with fibronectin and alpha5beta1 integrin. Exact colocalization of RI with fibronectin and its alpha5beta1 receptor was confirmed by double labeling and multiple-exposure photomicroscopy. In contrast, RIA bound to fibroblasts in a weak, patchy manner, showing only fine linear or granular staining. It is concluded that the adhesin component of RI targets the P. gingivalis arginine-protease to sites of fibronectin deposition on HGF, contributing to the rapid loss of both fibronectin and its main alpha5beta1 integrin receptor. Given the importance of integrin-ligand interactions in fibroblast function, their targeted disruption by RI may represent a novel mechanism of damage in periodontal disease.  (+info)

The potential role of chemokines and inflammatory cytokines in periodontal disease progression. (4/958)

Inflammation is regulated by the expression of mediators that cause a number of pleiotropic events culminating in the recruitment of inflammatory cells and release of biologic mediators by leukocytes. If the inflammation is transient in nature, it can protect the host by activating defense mechanisms and initiating wound repair. However, if the inflammation is inappropriate, it can lead to considerable tissue damage. My colleagues and I have investigated the role of chemokines, particularly monocyte chemoattractant protein 1, in various pathological processes and the role of the proinflammatory cytokines interleukin-1 (IL-1) and tumor necrosis factor (TNF) in experimental periodontitis. I will discuss first the studies on chemokines and then the use of IL-1 and TNF blockers in inhibiting inflammation and bone loss in the periodontium.  (+info)

Induction of prostaglandin release from macrophages by bacterial endotoxin. (5/958)

This review summarizes the role of the monocytic responses to lipopolysaccharide as it relates to periodontal disease severity. Data are presented which illustrate that the levels of prostaglandin E2 (PGE2) secreted by systemic peripheral blood monocytes in culture, in the presence of bacterial endotoxins, are highly correlated with the levels observed in the gingival crevicular fluid. Furthermore, the different periodontal diagnostic categories have varying levels of monocytic and crevicular fluid PGE2, in juxtaposition with clinical disease severity. These data are consistent with the concept that there is close synchrony between the systemic responsiveness of peripheral blood monocytes with regard to prostanoid synthesis and the local levels of mediator present within the gingival crevice.  (+info)

Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands. (6/958)

beta-Defensins are cationic peptides with broad-spectrum antimicrobial activity that are produced by epithelia at mucosal surfaces. Two human beta-defensins, HBD-1 and HBD-2, were discovered in 1995 and 1997, respectively. However, little is known about the expression of HBD-1 or HBD-2 in tissues of the oral cavity and whether these proteins are secreted. In this study, we characterized the expression of HBD-1 and HBD-2 mRNAs within the major salivary glands, tongue, gingiva, and buccal mucosa and detected beta-defensin peptides in salivary secretions. Defensin mRNA expression was quantitated by RNase protection assays. HBD-1 mRNA expression was detected in the gingiva, parotid gland, buccal mucosa, and tongue. Expression of HBD-2 mRNA was detected only in the gingival mucosa and was most abundant in tissues with associated inflammation. To test whether beta-defensin expression was inducible, gingival keratinocyte cell cultures were treated with interleukin-1beta (IL-1beta) or bacterial lipopolysaccharide (LPS) for 24 h. HBD-2 expression increased approximately 16-fold with IL-1beta treatment and approximately 5-fold in the presence of LPS. Western immunoblotting, liquid chromatography, and mass spectrometry were used to identify the HBD-1 and HBD-2 peptides in human saliva. Human beta-defensins are expressed in oral tissues, and the proteins are secreted in saliva; HBD-1 expression was constitutive, while HBD-2 expression was induced by IL-1beta and LPS. Human beta-defensins may play an important role in the innate defenses against oral microorganisms.  (+info)

Transcriptional activation of mRNA of intercellular adhesion molecule 1 and induction of its cell surface expression in normal human gingival fibroblasts by Mycoplasma salivarium and Mycoplasma fermentans. (7/958)

Lipoproteins in the cell membranes of both Mycoplasma salivarium and Mycoplasma fermentans were demonstrated to trigger the transcription of intercellular adhesion molecule-1 mRNA in normal fibroblasts isolated from human gingival tissue and to induce its cell surface expression by a mechanism distinct from that of Escherichia coli lipopolysaccharide. The lipid moiety of the lipoproteins was suggested to play a key role in the expression of the activity.  (+info)

Overgrowth of oral mucosa and facial skin, a novel feature of aspartylglucosaminuria. (8/958)

Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by deficiency of aspartylglucosaminidase (AGA). The main symptom is progressive mental retardation. A spectrum of different mutations has been reported in this disease, one missense mutation (Cys163Ser) being responsible for the majority of Finnish cases. We were able to examine 66 Finnish AGU patients for changes in the oral mucosa and 44 of these for changes in facial skin. Biopsy specimens of 16 oral lesions, 12 of them associated with the teeth, plus two facial lesions were studied histologically. Immunohistochemical staining for AGA was performed on 15 oral specimens. Skin was seborrhoeic in adolescent and adult patients, with erythema of the facial skin already common in childhood. Of 44 patients, nine (20%) had facial angiofibromas, tumours primarily occurring in association with tuberous sclerosis. Oedemic buccal mucosa (leucoedema) and gingival overgrowths were more frequent in AGU patients than in controls (p<0.001). Of 16 oral mucosal lesions studied histologically, 15 represented fibroepithelial or epithelial hyperplasias and were reactive in nature. Cytoplasmic vacuolisation was evident in four. Immunohistochemically, expression of AGA in AGU patients' mucosal lesions did not differ from that seen in corresponding lesions of normal subjects. Thus, the high frequency of mucosal overgrowth in AGU patients does not appear to be directly associated with lysosomal storage or with alterations in the level of AGA expression.  (+info)

Cytoprotective effects of grape seed extract on human gingival fibroblasts in relation to its antioxidant potential<...Cytoprotective effects of grape seed extract on human gingival fibroblasts in relation to its antioxidant potential<...
TY - JOUR. T1 - Cytoprotective effects of grape seed extract on human gingival fibroblasts in relation to its antioxidant potential. AU - Katsuda, Yusuke. AU - Niwano, Yoshimi. AU - Nakashima, Takuji. AU - Mokudai, Takayuki. AU - Nakamura, Keisuke. AU - Oizumi, Satomi. AU - Kanno, Taro. AU - Kanetaka, Hiroyasu. AU - Egusa, Hiroshi. N1 - Publisher Copyright: © 2015 Katsuda et al.. PY - 2015/8/10. Y1 - 2015/8/10. N2 - Cytoprotective effects of short-term treatment with grape seed extract (GSE) upon human gingival fibroblasts (hGFs) were evaluated in relation to its antioxidant properties and compared with those of a water-soluble analog of vitamin E: trolox (Tx). GSE and Tx showed comparable antioxidant potential in vitro against di(phenyl)-(2,4,6-trinitrophenyl)iminoazanium (DPPH; a stable radical), hydroxyl radical (·OH), singlet oxygen (1O2), and hydrogen peroxide (H2O2). Pretreatment or concomitant treatment with GSE for 1 min protected hGFs from oxidative stressors, including H2O2, ...
https://tohoku.pure.elsevier.com/en/publications/cytoprotective-effects-of-grape-seed-extract-on-human-gingival-fi-2
Establishment and characterization of a telomerase immortalized human gingival epithelial cell line<...Establishment and characterization of a telomerase immortalized human gingival epithelial cell line<...
TY - JOUR. T1 - Establishment and characterization of a telomerase immortalized human gingival epithelial cell line. AU - Moffatt-Jauregui, C. E.. AU - Robinson, B.. AU - de Moya, A. V.. AU - Brockman, R. D.. AU - Roman, A. V.. AU - Cash, M. N.. AU - Culp, D. J.. AU - Lamont, R. J.. N1 - Copyright: Copyright 2013 Elsevier B.V., All rights reserved.. PY - 2013/12. Y1 - 2013/12. N2 - Background and Objective: Gingival keratinocytes are used in model systems to investigate the interaction between periodontal bacteria and the epithelium in the initial stages of the periodontal disease process. Primary gingival epithelial cells (GECs) have a finite lifespan in culture before they enter senescence and cease to replicate, while epithelial cells immortalized with viral proteins can exhibit chromosomal rearrangements. The aim of this study was to generate a telomerase immortalized human gingival epithelial cell line and compare its in vitro behaviour to that of human GECs. Material and Methods: Human ...
https://augusta.pure.elsevier.com/en/publications/establishment-and-characterization-of-a-telomerase-immortalized-h
Impaired degradation of matrix collagen in human gingival fibroblasts by the antiepileptic drug phenytoin<...Impaired degradation of matrix collagen in human gingival fibroblasts by the antiepileptic drug phenytoin<...
TY - JOUR. T1 - Impaired degradation of matrix collagen in human gingival fibroblasts by the antiepileptic drug phenytoin. AU - Kato, Takahiro. AU - Okahashi, Nobuo. AU - Kawai, Shinji. AU - Kato, Takafumi. AU - Inaba, Hiroaki. AU - Morisaki, Ichijiro. AU - Amano, Atsuo. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2005/6. Y1 - 2005/6. N2 - Background: Gingival overgrowth (GO) is a serious adverse effect associated with the administration of phenytoin (PHT), with PHT-induced GO characterized by a massive accumulation of extracellular matrix components, especially collagen, in gingival connective tissues. However, the etiology of such collagen accumulation is still largely unknown. We examined the effects of PHT on the collagen degradation process leading to collagen accumulation in human gingival fibroblasts (HGF). Methods: HGFs were cultured with various concentrations of PHT and viable cell numbers and collagen amounts were determined. Gene and protein expressions ...
https://okayama.pure.elsevier.com/en/publications/impaired-degradation-of-matrix-collagen-in-human-gingival-fibrobl
RETRACTED ARTICLE: Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the...RETRACTED ARTICLE: Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the...
Porphyromonas gingivalis is the foremost oral pathogen of adult periodontitis in humans. However, the mechanisms of bacterial invasion and the resultant destruction of the gingival tissue remain largely undefined. We report host-P. gingivalis interactions in primary human gingival fibroblast (HGF) cells. Quantitative immunostaining revealed the need for a high multiplicity of infection for optimal infection. Early in infection (2-12 h), P. gingivalis activated the proinflammatory transcription factor NF-kappa B, partly via the PI3 kinase/AKT pathway. This was accompanied by the induction of cellular anti-apoptotic genes, including Bfl-1, Boo, Bcl-XL, Bcl2, Mcl-1, Bcl-w and Survivin. Late in infection (24-36 h) the anti-apoptotic genes largely shut down and the pro-apoptotic genes, including Nip3, Hrk, Bak, Bik, Bok, Bax, Bad, Bim and Moap-1, were activated. Apoptosis was characterized by nuclear DNA degradation and activation of caspases-3, -6, -7 and -9 via the intrinsic mitochondrial pathway. Use of
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-6-26/figures/5
RETRACTED ARTICLE: Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the...RETRACTED ARTICLE: Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the...
Porphyromonas gingivalis is the foremost oral pathogen of adult periodontitis in humans. However, the mechanisms of bacterial invasion and the resultant destruction of the gingival tissue remain largely undefined. We report host-P. gingivalis interactions in primary human gingival fibroblast (HGF) cells. Quantitative immunostaining revealed the need for a high multiplicity of infection for optimal infection. Early in infection (2-12 h), P. gingivalis activated the proinflammatory transcription factor NF-kappa B, partly via the PI3 kinase/AKT pathway. This was accompanied by the induction of cellular anti-apoptotic genes, including Bfl-1, Boo, Bcl-XL, Bcl2, Mcl-1, Bcl-w and Survivin. Late in infection (24-36 h) the anti-apoptotic genes largely shut down and the pro-apoptotic genes, including Nip3, Hrk, Bak, Bik, Bok, Bax, Bad, Bim and Moap-1, were activated. Apoptosis was characterized by nuclear DNA degradation and activation of caspases-3, -6, -7 and -9 via the intrinsic mitochondrial pathway. Use of
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-6-26/figures/9
A major human oral lysophosphatidic acid species, LPA 18:1, regulates novel genes in human gingival fibroblasts<...A major human oral lysophosphatidic acid species, LPA 18:1, regulates novel genes in human gingival fibroblasts<...
TY - JOUR. T1 - A major human oral lysophosphatidic acid species, LPA 18:1, regulates novel genes in human gingival fibroblasts. AU - Cerutis, D. Roselyn. AU - Weston, Michael D.. AU - Alnouti, Yazen. AU - Bathena, Sai P.. AU - Nunn, Martha E.. AU - Ogunleye, Afolabi O.. AU - McVaney, Timothy P.. AU - Headen, Karmel V.. AU - Miyamoto, Takanari. PY - 2015/5/1. Y1 - 2015/5/1. N2 - Background: The small bioactive lipid lysophosphatidic acid (LPA) plays critical roles in both normal physiology and inflammation in many systems. However, its actions are just beginning to be defined in oral biology and pathophysiology. Methods: Microarray analysis was used to test the hypothesis that human gingival fibroblasts (GFs) would show significant changes in wound-healing and inflammation-related gene transcripts in response to a major human salivary and gingival crevicular fluid LPA species, 18:1, and that they would express transcript for the major LPA-producing enzyme autotaxin. The microarray results were ...
https://creighton.pure.elsevier.com/en/publications/a-major-human-oral-lysophosphatidic-acid-species-lpa-181-regulate
Human gingival fibroblasts culture in an autologous scaffold and assessing its effect on augmentation of attached gingiva in a...Human gingival fibroblasts culture in an autologous scaffold and assessing its effect on augmentation of attached gingiva in a...
BACKGROUND AND AIM: An important goal of periodontal plastic surgery is the creation of attached gingiva around the teeth. In this study, the aims were to culture gingival fibroblasts in a biodegradable scaffold and measure the width of attached gingiva after the clinical procedure.METHODS: This study was carried out on 4 patients (8 sites), with inadequate attached gingiva next to at least two teeth in contralateral quadrants of the same jaw. A biopsy of attached gingiva (epithelial + connective tissue) was taken using a surgical blade. Following culture of gingival fibroblasts, 250 × 103 cells in 250 µl nutritional medium were mixed with platelet-rich in growth factor (PRGF). Periosteal fenestration technique was done on one side (control) and tissue-engineered mucosal graft (test) was carried out on the contralateral side in each patient. The width of keratinized tissue, probing depth (PD) and width of attached gingiva were recorded at baseline and 3 months after the operation.RESULTS: An increased
http://johoe.kmu.ac.ir/index.php/article_84876.html
Nitric oxide inhibits androgen receptor-mediated collagen production in human gingival fibroblasts<...Nitric oxide inhibits androgen receptor-mediated collagen production in human gingival fibroblasts<...
TY - JOUR. T1 - Nitric oxide inhibits androgen receptor-mediated collagen production in human gingival fibroblasts. AU - Lin, S. J.. AU - Lu, H. K.. AU - Lee, H. W.. AU - Chen, Y. C.. AU - Li, C. L.. AU - Wang, Leng-Fang. PY - 2012/12. Y1 - 2012/12. N2 - Background and Objective: In our previous study, we found that flutamide [an androgen receptor (AR) antagonist] inhibited the up-regulation of collagen induced by interleukin (IL)-1β and/or nifedipine in gingival fibroblasts. The present study attempted to verify the role of nitric oxide (NO) in the IL-1β/nifedipine-AR pathway in gingival overgrowth. Material and Methods: Confluent gingival fibroblasts derived from healthy individuals (n=4) and those with dihydropyridine-induced gingival overgrowth (DIGO) (n=6) were stimulated for 48h with IL-1β (10ng/mL), nifedipine (0.34μm) or IL-1β + nifedipine. Gene and protein expression were analyzed with real-time RT-PCR and western blot analyses, respectively. Meanwhile, Sircol dye-binding and the ...
https://tmu.pure.elsevier.com/zh/publications/nitric-oxide-inhibits-androgen-receptor-mediated-collagen-product
Nitric oxide synthase type-II is synthesized by human gingival...Nitric oxide synthase type-II is synthesized by human gingival...
Nitric oxide synthase type-II is synthesized by human gingival tissue and cultured human gingival fibroblasts.: Nitric oxide is known to be an important inflamm
https://www.mysciencework.com/publication/show/nitric-oxide-synthase-type-ii-synthesized-human-gingival-tissue-cultured-human-gingival-fibroblasts-a284280a
Håvard Jostein Haugen - Institutt for klinisk odontologiHåvard Jostein Haugen - Institutt for klinisk odontologi
Gomez-Florit, Manuel; Ramis, Joana Maria; Xing, Rui; Taxt-Lamolle, Sebastien Francis Michel; Haugen, Håvard Jostein; Lyngstadaas, Ståle Petter & Monjo Cabrer, Marta (2014). Differential response of human gingival fibroblasts to titanium- and titanium-zirconium-modified surfaces. Journal of Periodontal Research. ISSN 0022-3484. 49(4), s 425- 436 . doi: 10.1111/jre.12121 Vis sammendrag Background and Objective: Gingival fibroblasts are responsible for the constant adaptation, wound healing and regeneration of gingival connective tissue. New titanium-zirconium (TiZr) abutment surfaces have been designed to improve soft tissue integration and reduce implant failure compared with titanium (Ti). The aim of the present study was firstly to characterize a primary human gingival fibroblasts (HGF) model and secondly to evaluate their differential response to Ti and TiZr polished (P), machined (M), and machined + acid-etched (modMA) surfaces, respectively. Material and Methods: HGF were cultured on ...
http://www.odont.uio.no/iko/personer/vit/haavarjh/
pH and the effect of NH4Cl on human gingival fibroblasts. - PubMed - NCBIpH and the effect of NH4Cl on human gingival fibroblasts. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/3856925?dopt=Abstract
High-frequency low-level diode laser irradiation promotes proliferation and migration of primary cultured human gingival...High-frequency low-level diode laser irradiation promotes proliferation and migration of primary cultured human gingival...
In periodontal therapy, the use of low-level diode lasers has recently been considered to improve wound healing of the gingival tissue. However, its effects on human gingival epithelial cells (HGECs)...
https://link.springer.com/article/10.1007%2Fs10103-013-1292-7
Active Nanofibrous Membrane Effects on Gingival Cell Inflammatory Response - Semantic ScholarActive Nanofibrous Membrane Effects on Gingival Cell Inflammatory Response - Semantic Scholar
Alpha-melanocyte stimulating hormone (α-MSH) is involved in normal skin wound healing and also has anti-inflammatory properties. The association of α-MSH to polyelectrolyte layers with various supports has been shown to improve these anti-inflammatory properties. This study aimed to evaluate the effects of nanofibrous membrane functionalized with α-MSH linked to polyelectrolyte layers on gingival cell inflammatory response. Human oral epithelial cells (EC) and fibroblasts (FB) were cultured on plastic or electrospun Poly-#-caprolactone (PCL) membranes with α-MSH covalently coupled to Poly-L-glutamic acid (PGA-α-MSH), for 6 to 24 h. Cells were incubated with or without Porphyromonas gingivalis lipopolysaccharide (Pg-LPS). Cell proliferation and migration were determined using AlamarBlue test and scratch assay. Expression of interleukin-6 (IL-6), tumor necrosis factor (TNF-α), and transforming growth factor-beta (TGF-β) was evaluated using RT-qPCR method. Cell cultures on plastic showed that PGA-α
https://www.semanticscholar.org/paper/Active-Nanofibrous-Membrane-Effects-on-Gingival-Ce-Morand-Huck/da4fb8c47e4f5ed6c7b92fc1498526ed56150fab
Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by...Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by...
Irsogladine maleate (IM) counters Aggregatibacter actinomycetemcomitans-induced reduction of the gap junction intercellular communication and the expression of zonula occludens-1, which is a major tight junction structured protein, in cultured human gingival epithelial cells (HGEC). In addition, IM obviates the A. actinomycetemcomitans-induced increase in interleukin (IL)-8 levels in HGEC. Thus, by regulating the intercellular junctional complex and chemokine secretion in HGEC, IM may be useful to prevent periodontal disease. To clarify the effects and regulatory mechanism of IM in vivo and in vitro, we examined the expression of E-cadherin and neutrophil chemotaxis induced by A. actinomycetemcomitans under IM pretreatment. Immunohistochemical studies revealed that A. actinomycetemcomitans application to the gingival sulcus decreased the number of cells positive for E-cadherin and increased those positive for cytokine-induced neutrophil chemoattractant-2α (CINC-2α) in rat gingival epithelium ...
https://ir.lib.hiroshima-u.ac.jp/en/list/HU_creator/%E3%82%A6/29f94f2e4afc50d7520e17560c007669/item/32185
Preventive Effect of Daiokanzoto TJ-84 on 5-Fluorouracil-Induced Human Gingival Cell Death through the Inhibition of Reactive...Preventive Effect of Daiokanzoto TJ-84 on 5-Fluorouracil-Induced Human Gingival Cell Death through the Inhibition of Reactive...
Preventive Effect of Daiokanzoto TJ-84 on 5-Fluorouracil-Induced Human Gingival Cell Death through the Inhibition of Reactive Oxygen Species Production. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
http://libros.duhnnae.com/2017/jun9/149843798149-Preventive-Effect-of-Daiokanzoto-TJ-84-on-5-Fluorouracil-Induced-Human-Gingival-Cell-Death-through-the-Inhibition-of-Reactive-Oxygen-Species-Productio.php
Root Coverage with Cultured Gingival Dermal Substitute Composed of Gingival Fibroblasts and Matrix: A Case SeriesRoot Coverage with Cultured Gingival Dermal Substitute Composed of Gingival Fibroblasts and Matrix: A Case Series
DOI: 10.11607/prd.00.0824 Cultured gingival dermal substitute (CGDS), composed of gingival fibroblasts and matrix and fabricated using tissue-engineering techniques, has been used for root coverage procedures. Fourteen sites from four patients with ≥ 2 mm of Miller Class I or II facial gingival tissue recession were treated. The autologous CGDS sheet, prepared prior to surgical treatment, was grafted over the teeth with gingival recession and then covered with a coronally positioned flap. Vertical and horizontal recession was measured at baseline (prior to the surgical procedure) and 13 to 40 weeks (average: 30.7 9.6 weeks) after surgery. The average vertical and horizontal root coverage after surgery was 79.1% 25.7% and 75.2% 31.4%, respectively. Moreover, there was a significant increase of keratinized and attached gingival tissue at the final clinical evaluation compared with preoperative measurements (P < .05). These results demonstrate CGDS as a promising grafting material for use with ...
http://www.quintpub.com/journals/prd/abstract.php?iss2_id=285&article_id=3546&article=4&title=Root%20Coverage%20with%20Cultured%20Gingival%20Dermal%20Substitute%20Composed%20of%20Gingival%20Fibroblasts%20and%20Matrix:%20A%20Case%20Series
Human Gingival Fibroblasts - Science PROHuman Gingival Fibroblasts - Science PRO
Human Gingival Fibroblasts https://www.sciencepro.com.br/produtos/sc-2620 https://www.sciencepro.com.br/@@site-logo/logo-novo.png ...
https://www.sciencepro.com.br/produtos/sc-2620
Combination of ions promotes cell migration via extracellular signal-regulated kinase 1/2 signaling pathway in human gingival...Combination of ions promotes cell migration via extracellular signal-regulated kinase 1/2 signaling pathway in human gingival...
Wound healing is a dynamic process that involves highly coordinated cellular events, including proliferation and migration. Oral gingival fibroblasts serve a central role in maintaining oral mucosa homeostasis, and their functions include the coordination of physiological tissue repair. Recently, surface pre‑reacted glass‑ionomer (S‑PRG) fillers have been widely applied in the field of dental materials for the prevention of dental caries, due to an excellent ability to release fluoride (F). In addition to F, S‑PRG fillers are known to release several types of ions, including aluminum (Al), boron (B), sodium (Na), silicon (Si) and strontium (Sr). However, the influence of these ions on gingival fibroblasts remains unknown. The aim of the present study was to examine the effect of various concentrations of an S‑PRG filler eluate on the growth and migration of gingival fibroblasts. The human gingival fibroblast cell line HGF‑1 was treated with various dilutions of an eluent solution of ...
https://repo.lib.tokushima-u.ac.jp/en/list/author-page/60440/item/113289
ORBi: Browsing ORBiORBi: Browsing ORBi
in Journal of Periodontal Research (1999), 34(6), 323-8. Several grafting techniques and guided tissue regeneration techniques (GTR) have been well-developed in periodontal surgery. However, these techniques could induce pain and side effects, such as a ... [more ▼]. Several grafting techniques and guided tissue regeneration techniques (GTR) have been well-developed in periodontal surgery. However, these techniques could induce pain and side effects, such as a gingival recession during the healing period following the therapy. The graft of a small autologous connective tissue, using non-invasive surgical techniques could yield several benefits for the patients. Our preliminary study explores the feasibility of collecting healthy gingival tissues, culturing them in vitro to amplify rat gingival fibroblasts (RGF) and inoculating the obtained cells into autologous rat gingival tissues in vivo. Gingival tissues samples were cultured as explants as described by Freshney et al. and Adolphe. ...
http://orbi.ulg.ac.be/browse?type=author&value=Simain-Sato,%20Franklin%20p007583
Quintessence PublishingQuintessence Publishing
Objective: To investigate the contribution of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) to PGE2 production in human gingival fibroblast cells stimulated with lipopolysaccharide from periodontopathogenic bacteria. Methods: Lipopolysaccharide was isolated from Porphyromonas gingivalis and Prevotella intermedia by the phenol-water method. Human gingival fibroblast cells were stimulated with lipopolysaccharide in different concentration for different time periods. The levels of PGE2 in the culture medium were measured by radioimmunoassay. The expression of COX-2 protein was observed by immunocytochemical staining; COX-1 and COX-2 mRNA expression were examined by semi-quantitative RT-PCR analysis. Results: The production of PGE2 in human gingival fibroblast cells was increased in a time- and dose-dependent manner (P < .01, P < .01). Immunocytochemical staining showed the positive expression of COX-2 protein in stimulated cells around the unstained cell nucleus, while no expression was ...
http://www.quintpub.com/journals/cjdr/archive_display_abstract.php3?journalArt=5419
Gingival Fibroblasts as Autologous Feeders for Induced Pluripotent Stem Cells<...Gingival Fibroblasts as Autologous Feeders for Induced Pluripotent Stem Cells<...
TY - JOUR. T1 - Gingival Fibroblasts as Autologous Feeders for Induced Pluripotent Stem Cells. AU - Yu, G.. AU - Okawa, H.. AU - Okita, K.. AU - Kamano, Y.. AU - Wang, F.. AU - Saeki, M.. AU - Yatani, H.. AU - Egusa, H.. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Human gingival fibroblasts (hGFs) present an attractive source of induced pluripotent stem cells (iPSCs), which are expected to be a powerful tool for regenerative dentistry. However, problems to be addressed prior to clinical application include the use of animal-derived feeder cells for cultures. The aim of this study was to establish an autologous hGF-derived iPSC (hGF-iPSC) culture system by evaluating the feeder ability of hGFs. In both serum-containing and serum-free media, hGFs showed higher proliferation than human dermal fibroblasts (hDFs). Three hGF strains were isolated under serum-free conditions, although 2 showed impaired proliferation. When hGF-iPSCs were transferred onto mitomycin C-inactivated hGFs, hDFs, or mouse-derived SNL ...
https://tohoku.pure.elsevier.com/en/publications/gingival-fibroblasts-as-autologous-feeders-for-induced-pluripoten
C57BL/6-GFP Mouse Gingival Epithelial Cells | Creative BioarrayC57BL/6-GFP Mouse Gingival Epithelial Cells | Creative Bioarray
C57BL/6-GFP Mouse Gingival Epithelial Cells from Creative Bioarray are isolated from C57BL/6-GFP-Tg(CAG-EGFP)1Osb/J mouse gingival tissue of pathogen-free laboratory mice. C57BL/6-GFP Mouse Gingival Epithelial Cells are grown in a T25 tissue culture flask pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarrays Culture Complete Growth Medium for 3-5 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 0.5x10^6 cells per ml and is delivered frozen. These cells are pre-coated with EpCAM-1 (CD326) antibody, following the application of magnetic beads pre-coated with secondary antibody Cells can be expanded for 3-7 passages at a split ratio of 1:2 under the cell culture conditions specified by Creative Bioarray. Repeated freezing and thawing of cells is not recommended ...
https://www.creative-bioarray.com/C57BL-6-GFP-Mouse-Gingival-Epithelial-Cells-CSC-C9095J-item-41520.htm
Hamster Gingival Epithelial Cells | Creative BioarrayHamster Gingival Epithelial Cells | Creative Bioarray
Hamster Gingival Epithelial Cells from Creative Bioarray are isolated from gingival tissue of pathogen-free laboratory mice. Hamster Gingival Epithelial Cells are grown in a T25 tissue culture flask pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarrays Culture Complete Growth Medium for 3-5 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 0.5x10^6 cells per ml and is delivered frozen. Cells can be expanded for 3-7 passages at a split ratio of 1:2 under the cell culture conditions specified by Creative Bioarray. Repeated freezing and thawing of cells is not recommended ...
https://www.creative-bioarray.com/Hamster-Gingival-Epithelial-Cells-CSC-C9199J-item-41603.htm
Acervo Digital: Effect of LPS treatment on the viability and chemokine synthesis by epithelial cells and gingival fibroblastsAcervo Digital: Effect of LPS treatment on the viability and chemokine synthesis by epithelial cells and gingival fibroblasts
Objective: Several local factors can affect the wound-healing process, delaying its progression and postponing tissue homeostasis. It is known that local inflammation is related to wound healing; however, the maintenance of the inflammatory reaction can impair the proliferation and migration of oral mucosal cells. The aim of this study was to evaluate the viability and chemokine expression of epithelial cells and gingival fibroblasts exposed to long-term lipopolysaccharide (LPS) treatment. Design: Epithelial cells (HaCaT, Cell Lines Service, 300493) and human gingival fibroblasts (HGFs) were seeded (1 105 cells/well) in 24-well plates and incubated for 24 h. To simulate the responses of cells to a local chronic oral mucosal inflammation, we added LPS of Escherichia coli (10 mg/ml) to Dulbeccos modified Eagles medium (DMEM), kept in contact with fibroblasts and epithelial cells for 24, 48, and 72 h. Then the cells were assessed for viability (alamarBlue assay), number (trypan blue assay), and ...
https://acervodigital.unesp.br/handle/11449/125721?mode=full
Hormones of Pregnancy Effects on Gingival Fibroblasts - Carol LappHormones of Pregnancy Effects on Gingival Fibroblasts - Carol Lapp
Gornstein, R A; Lapp, C A; Bustos-Valdes, S M et al. (1999) Androgens modulate interleukin-6 production by gingival fibroblasts in vitro. J Periodontol 70:604-9 ...
https://grantome.com/grant/NIH/R03-DE010391-02
Gene Expression Profiles in Paired Gingival Biopsies from Periodontitis-Affected and Healthy Tissues Revealed by Massively...Gene Expression Profiles in Paired Gingival Biopsies from Periodontitis-Affected and Healthy Tissues Revealed by Massively...
Periodontitis is a chronic inflammatory disease affecting the soft tissue and bone that surrounds the teeth. Despite extensive research, distinctive genes responsible for the disease have not been identified. The objective of this study was to elucidate transcriptome changes in periodontitis, by investigating gene expression profiles in gingival tissue obtained from periodontitis-affected and healthy gingiva from the same patient, using RNA-sequencing. Gingival biopsies were obtained from a disease-affected and a healthy site from each of 10 individuals diagnosed with periodontitis. Enrichment analysis performed among uniquely expressed genes for the periodontitis-affected and healthy tissues revealed several regulated pathways indicative of inflammation for the periodontitis-affected condition. Hierarchical clustering of the sequenced biopsies demonstrated clustering according to the degree of inflammation, as observed histologically in the biopsies, rather than clustering at the individual ...
http://kth.diva-portal.org/smash/record.jsf?pid=diva2:570712
Mahidol Universitys Institutional Repository (Mahidol IR): Human papillomavirus 16 E6/E7-immortalized human gingival...Mahidol Universitys Institutional Repository (Mahidol IR): Human papillomavirus 16 E6/E7-immortalized human gingival...
Epithelial mesenchymal transition (EMT) has been implicated in neoplastic invasion and metastasis. We have previously generated six cell lines from human gingival mucosal keratinocytes immortalized by E6/E7 of human papillomavirus type 16. Ldk and NuB1 lines represented EMT phenotype and other four lines represented cobblestone non-EMT phenotype. These cell lines were utilized as model cells to determine whether inhibitors of apoptosis proteins and cell-cycle regulators were molecular players during EMT. EMT cells exhibited increased expression of vimentin, vascular endothelial growth factor (VEGF) receptor1 and the ability to form tubules on Matrigel as well as to grow anchorage independently. We found that EMT cells expressed significantly elevated levels of cIAP-1, Bclx and p27 kip higher than non-EMT cells. These proteins could therefore be used as intrinsic indicators of EMT of human gingival keratinocytes. © 2009 John Wiley & Sons A/S ...
http://repository.li.mahidol.ac.th/dspace/handle/123456789/27103?mode=full
Adhesion and Proliferation of Human Gingival Fibroblasts on Root Surfaces following Photodynamic Therapy: An In Vitro Study -...Adhesion and Proliferation of Human Gingival Fibroblasts on Root Surfaces following Photodynamic Therapy: An In Vitro Study -...
Background and Aim: Previous studies have shown that some dyes used in photodynamic therapy (PDT) have a low pH and may cause root demineralization and remove the smear layer. This study aimed to assess and compare the effects of root biomodification with citric acid and PDT on the adhesion and proliferation ...
http://jidai.ir/article-1-2050-en.html
Human Gingival FibroblastsHuman Gingival Fibroblasts
Fibroblasts are quality tested in FibroLife® S2 or FibroLife® Xeno-Free Medium to ensure proper growth and morphology for at least 15 population doublings.
https://www.lifelinecelltech.com/shop/cells/fibroblasts/mouth-fibroblasts/human-gingival-fibroblasts-fc-0095/
Lidocaine-Induced Cell Growth of Human Gingival Fibroblasts. Role of Na<sup>+</sup>-K<sup>+</sup>-ATPase and PKC...Lidocaine-Induced Cell Growth of Human Gingival Fibroblasts. Role of Na<sup>+</sup>-K<sup>+</sup>-ATPase and PKC...
Background: Evidences have shown that local anaesthetics are clinically useful compounds that exert a pharmacological effect by blocking nerve impulse propagation and also it is able to provoke proliferation and cell growth. Aims: The aim of this study w...
http://www.oalib.com/paper/3111635
Bacterial induced apoptosis in MG63 cells and human gingival fibroblasts in vitro. - UCL DiscoveryBacterial induced apoptosis in MG63 cells and human gingival fibroblasts in vitro. - UCL Discovery
UCL Discovery is UCLs open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
http://discovery.ucl.ac.uk/1332809/
Paper: Biocompatibility of light-cured orthodontic bonding adhesives: a preliminary study (AADR Annual Meeting (March 21-24,...Paper: Biocompatibility of light-cured orthodontic bonding adhesives: a preliminary study (AADR Annual Meeting (March 21-24,...
Direct bonding of orthodontic brackets is an established procedure and has lead to increasing number of light-cured bonding materials produced with ever-increasing bond strength and ease of delivery. However, considerably less attention is given to biocompatibility of these materials. Both in vivo and in vitro studies indicate orthodontic bonding agents are cytotoxic. Spectrophotometric analysis revealed that these resins contained a great amount of potentially toxic, leachable, un-polymerized material, even when fully cured. Hypothesis: Different light-cured bonding agents may have different cytotoxic effects depending on their chemistry. Objective: Compare and analyze the toxicity of three different light-cured bonding agents to a population of gingival cells as measured by cell growth, and viability in vitro. Method: Light Bond®, MonoLok®, and Transbond XT® orthodontic adhesives were tested. Human gingival cells were obtained from extracted third molars, pooled, and expanded until needed. ...
http://www-personal.umich.edu/~sbayne/DMG/DMG-Publications/IADR-AADR-Meeting-Program-Books/2012-AADR-Tampa/2012-AADR-Tampa-CD/AADR12/Paper158445.html
Biology-OnlineBiology-Online
THEODORE ROSETT, PAMELA S. GARNER, and LOUIS P. GANGAROSA Department of Biochemistry, Temple University School of Dentistry, Philadelphia, Pennsylvania, 19140, USA and Department of Oral Biology, Medical College of Georgia, Augusta, Georgia J Dent Res May-June 1972, Vol 51 No. 3 Previous studies (RoSETT ET AL, J Dent Res 50:161, 1971; GANGAROSA and ROSETT, J Dent Res 50:163, 1971) and the present one aim to determine physiologic and metabolic processes in human gingival tissue to discover how these processes are altered during the induction of periodontal disease. We chose cattle gingival epithelium to have a readily available supply of tissues. In this study we investigated the normal levels of some enzymes involved in glucose metabolism within bovine attached gingival epithelium. In determining the relative levels of the enzyme in any particular series of metabolic pathways, it is emphasized that we are only reporting the potential for conversion of substrate to product. The existence of these ...
https://www.biology-online.org/articles/studies_biochemistry_oral_tissue/article.html
The combined effects of irradiation and herpes simplex virus type 1 infection on an immortal gingival cell line | Virology...The combined effects of irradiation and herpes simplex virus type 1 infection on an immortal gingival cell line | Virology...
Oral mucosa is frequently exposed to Herpes simplex virus type 1 (HSV-1) infection and irradiation due to dental radiography. During radiotherapy for oral cancer, the surrounding clinically normal tissues are also irradiated. This prompted us to study the effects of HSV-1 infection and irradiation on viability and apoptosis of oral epithelial cells. Immortal gingival keratinocyte (HMK) cells were infected with HSV-1 at a low multiplicity of infection (MOI) and irradiated with 2 Gy 24 hours post infection. The cells were then harvested at 24, 72 and 144 hours post irradiation for viability assays and qRT-PCR analyses for the apoptosis-related genes caspases 3, 8, and 9, bcl-2, NFκB1, and viral gene VP16. Mann-Whitney U-test was used for statistical calculations. Irradiation improved the cell viability at 144 hours post irradiation (P = 0.05), which was further improved by HSV-1 infection at MOI of 0.00001 (P = 0.05). Simultaneously, the combined effects of infection at MOI of 0.0001 and irradiation
https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-11-125
Traditional and Emerging Diagnostic Strategies for Identifying Risk | Compendium of Continuing Education in Dentistry (Suppl) |...Traditional and Emerging Diagnostic Strategies for Identifying Risk | Compendium of Continuing Education in Dentistry (Suppl) |...
Dental professionals are well positioned to educate patients about the overall health implications of chronic inflammation, particularly relating to periodontal disease. A greater understanding of the role of inflammation in various seemingly unrelated conditions allows practitioners to provide alternative strategies for prevention while resolving inflammation to reduce the risk of various systemic conditions.2. Periodontitis occurs when bacteria trigger inflammation with the release of various biochemical mediators, such as cytokines, which may lead to the destruction of gingival connective tissue and bone.3 Chronic adult periodontitis is the common form of this bacterially induced inflammatory disease, which affects a substantial number of adults and has shown to be a significant contributing factor to other systemic conditions.4 Chronic diseases such as atherosclerotic cardiovascular disease, rheumatoid arthritis, and diabetes mellitus may develop or worsen in part due to uncontrolled ...
https://aap.cdeworld.com/courses/21208-traditional-and-emerging-diagnostic-strategies-for-identifying-risk
Unscramble gingival | Words unscrambled from letters gingival | Scrabble Word gingival | Words Made with the Letters gingivalUnscramble gingival | Words unscrambled from letters gingival | Scrabble Word gingival | Words Made with the Letters gingival
Unscramble gingival, Unscramble letters gingival, Point value for gingival, Word Decoder for gingival, Word generator using the letters gingival, Word Solver gingival, Possible Scrabble words with gingival, Anagram of gingival
http://www.allscrabblewords.com/word-description/gingival
Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells - ResearchOnlineBiofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells - ResearchOnline
TY - JOUR. T1 - Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells. AU - Brown, Jason L.. AU - Johnston, William. AU - Delaney, Chris. AU - Rajendran, Ranjith AU - Butcher, John. AU - Khan, Shaz. AU - Bradshaw, David. AU - Ramage, Gordon. AU - Culshaw, Shauna. N1 - Acceptance from webpage OA article. PY - 2019/10/31. Y1 - 2019/10/31. N2 - The gingival epithelium is a physical and immunological barrier to the microbiota of the oral cavity, which interact through soluble mediators with the immune cells that patrol the tissue at the gingival epithelium. We sought to develop a three-dimensional gingivae-biofilm interface model using a commercially available gingival epithelium to study the tissue inflammatory response to oral biofilms associated with health, gingivitis and periodontitis.. These biofilms were developed by sequential addition of microorganisms to mimic the formation of supra- and sub-gingival plaque in vivo. Secondly, to mimic the ...
https://researchonline.gcu.ac.uk/en/publications/biofilm-stimulated-epithelium-modulates-the-inflammatory-response
General Dentistry DetailsGeneral Dentistry Details
Nadine Krockow. The aim of this literature review was to define the most favorable surface topography and macrodesign of the transmucosal zone of abutments to achieve optimal soft tissue seal. A search identified 12 articles-3 human studies, 3 animal studies, and 6 in vitro studies-meeting the inclusion criteria for final evaluation. The human histologic studies showed that laser-ablated, hydrophilic, and oxidized titanium surfaces result in perpendicular insertion of human gingival fibroblasts into the treated abutment surface. Epithelial cells seem to slightly favor zirconia and polished titanium surfaces.. 2018 January/February; 66(1):18-25. ...
http://www.agd.org/publications-and-news/general-dentistry/general-dentistry-details/january-february-2018
Heme Oxygenase - Discovery of novel inhibitors for the treatment of glaucomaHeme Oxygenase - Discovery of novel inhibitors for the treatment of glaucoma
Gingival and osseous augmentations are reported while hypertrophic or hyperplastic reactions to different factors including chronic traumatisms and surgeries such as free gingival graft (FGG) that induce an abnormal growth of both hard and soft cells in genetically predisposed subjects. methods, and the manifestation of genes and proteins involved in collagen synthesis, maturation, and degradation was assessed in cultured fibroblasts from gingival fragments in the molecular level. Our results display that general morphology and collagen content material were related in healthy and overgrown gingivae. However, fibroblasts from the overgrown gingiva exposed an anabolic phenotype characterized by an increased collagen turnover and maturation. These findings indicate that an exostosis could act as a mechanical stimulus stretching the overlying connective cells and triggering an anabolic phenotype of gingival fibroblasts AZ7371 and suggest to use minimally invasive operative techniques to prevent ...
http://desafioceroaedes.com/category/heme-oxygenase/
Scholarship 16/01161-6 - Health Sciences - BV FAPESPScholarship 16/01161-6 - Health Sciences - BV FAPESP
Titanium tetrafluoride solutions: occlusion of dentinal tubules and citotoxicity on gingival fibroblasts. Scholarships in Brazil Scientific Initiation. Eliza Maximiano Cury. Health Sciences
https://bv.fapesp.br/en/bolsas/164874/titanium-tetrafluoride-solutions-occlusion-of-dentinal-tubules-and-citotoxicity-on-gingival-fibrobl/
Tag Cytokine - LoveDoc.OrgTag Cytokine - LoveDoc.Org
409 Role of Neutrophils in Periodontal Disease 051205_lecture32 Artigo DENGUE In Adv Nutr 2011 Wallace 1 7 Osteoarthritis Interleukin-6 and Tumor Necrosis Factor-A Production After Acute Psychological Cytotoxicity of Resin Monomers on Human Gingival Fib Rob Lasts and HaCaT Keratinocytes Cell Communication Biology Tooth Movement Interluekin The Effects of Ursolic Acid on Cytokine Production Sepsis.pptx
https://lovedoc.org/tag/cytokine
Gingival keratinization-Review | International Journal of Current ResearchGingival keratinization-Review | International Journal of Current Research
The keratinized oral gingival epithelium provides effective protection against both mechanical trauma and bacterial invasion. The horny cell layer acts like a film of plastic wrap, allowing the body to retain moisture and protecting it from invasion by foreign substances and comprises various substances such as keratins, produced by the epidermal keratinocytes and lipids. The epidermal keratinocytes divide in the basal layer, produce keratins and differentiate, and migrate to the upper layers as they mature by a process called keratinization. The present review discusses the structure of keratin, the process of keratinization and their distribution in gingival epithelium.. ...
https://www.journalcra.com/article/gingival-keratinization-review
Acetylsalicylic Acid Rescues the Immunomodulation of Inflamed Gingiva-Derived Mesenchymal Stem Cells via Upregulating FasL in...Acetylsalicylic Acid Rescues the Immunomodulation of Inflamed Gingiva-Derived Mesenchymal Stem Cells via Upregulating FasL in...
This study indicates that the deficient immunomodulatory function of iGMSCs could be rescued by ASA pretreatment via upregulating of FasL in mice. This strategy might serve as a practical approach to rescue deficient MSC function for further therapeutic application.
https://pubmed.ncbi.nlm.nih.gov/31796122/
The role of toll-like and protease-activated receptors in the expression of cytokines by gingival fibroblasts stimulated with...The role of toll-like and protease-activated receptors in the expression of cytokines by gingival fibroblasts stimulated with...
Advanced search is divided into two main parts, and one or more groups in each of the main parts. The main parts are the Search for (including) and the Remove from search (excluding) part. (The excluding part might not be visible until you hit NOT for the first time ...
http://oru.diva-portal.org/smash/record.jsf?faces-redirect=true&language=en&searchType=RESEARCH&query=&af=%5B%5D&aq=%5B%5B%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&pid=diva2%3A792586&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
KAKEN - Research Projects | Isolation of Phospholipase A 2 Activating Peptide From Inflamed Gingival Tissues. (KAKENHI-PROJECT...KAKEN - Research Projects | Isolation of Phospholipase A 2 Activating Peptide From Inflamed Gingival Tissues. (KAKENHI-PROJECT...
Principal Investigator：SAITO Kihachi, Project Period (FY)：1989 - 1990, Research Category：Grant-in-Aid for General Scientific Research (C), Research Field：Functional basic dentistry
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01571014/
KAKEN - Researchers | YANASE Hiroshi (10211616)KAKEN - Researchers | YANASE Hiroshi (10211616)
Affiliation：愛知学院大学,歯学部,講師, Research Field：矯正・小児・社会系歯学,小児・社会系歯学, Keywords：歯周疾患,小児,細胞増殖能,b-FGF,サイトカイン,PDGF-AB,Down Syndrome,gingival fibroblasts,growth activity,歯肉線維芽細胞, # of Research Projects：7, # of Research Products：0
https://nrid.nii.ac.jp/nrid/1000010211616/
Seretide Side Effects - Page 2Seretide Side Effects - Page 2
Dont take Seretide without checking for Side Effects | A female patient was diagnosed with asthma, gingival disorder, treated with SERETIDE and reported asthmatic crisis,gingival disorder,gingival pain. Dosage: .
http://www.patientsville.com/medication/seretide2_side_effects.htm
Other Gingival Disorders - Dental Disorders - Merck Manuals Professional EditionOther Gingival Disorders - Dental Disorders - Merck Manuals Professional Edition
Learn about the causes, symptoms, diagnosis & treatment of Periodontal Disorders from the Professional Version of the Merck Manuals.
https://www.merckmanuals.com/en-pr/professional/dental-disorders/periodontal-disorders/other-gingival-disorders
Human gingival fibroblast feeder cells promote maturation of induced pluripotent stem cells into cardiomyocytes<...Human gingival fibroblast feeder cells promote maturation of induced pluripotent stem cells into cardiomyocytes<...
TY - JOUR. T1 - Human gingival fibroblast feeder cells promote maturation of induced pluripotent stem cells into cardiomyocytes. AU - Matsuda, Yusuke. AU - Takahashi, Ken. AU - Kamioka, Hiroshi. AU - Naruse, Keiji. PY - 2018/9/10. Y1 - 2018/9/10. N2 - The use of human induced pluripotent stem (iPS) cells has been investigated in multiple regenerative medicine studies. However, although methods for efficient differentiation of iPS cells into heart tissues have been devised, it remains difficult to obtain cardiac tissue with high contractility. Herein, we established a method for differentiating iPS cells into highly contractile cardiomyocytes (CMs), and demonstrate that the use of human gingival fibroblasts (HGFs) as a feeder cells promotes maturation of iPS-derived CMs (iPS-CMs) in vitro. After CM differentiation of iPS cells, iPS-CMs showed increased mRNA expression of the CM specific maker cardiac troponin T (cTnT) in the absence and presence (on-feeder condition) of cocultured HGFs, and ...
https://okayama.pure.elsevier.com/en/publications/human-gingival-fibroblast-feeder-cells-promote-maturation-of-indu
Molecules | Free Full-Text | Biological Effects of Shikonin in Human Gingival Fibroblasts via ERK 1/2 Signaling Pathway | HTMLMolecules | Free Full-Text | Biological Effects of Shikonin in Human Gingival Fibroblasts via ERK 1/2 Signaling Pathway | HTML
Shikonin, an active ingredient of Lithospermum erythrorhizon, exerts anti-inflammatory and antibacterial effects, and promotes wound healing. We investigated whether shikonin stimulated gingival tissue wound healing in human gingival fibroblasts (hGF). In addition, we evaluated the effects of shikonin on the mitogen-activated protein kinase (MAPK) signaling pathway, which has an important role in wound healing. hGF were subjected to primary culture using gingiva collected from patients. The cells were exposed to/treated with Shikonin at concentrations ranging from 0.01 to 100 μM. The optimal concentration was determined by cell proliferation and migration assays. Type I collagen and fibronectin synthesis, the gene expression of vascular endothelial growth factor (VEGF) and FN, and the phosphorylation of Extracellular signal-regulated kinase (ERK) 1/2 were investigated. Identical experiments were performed in the presence of PD98059 our data suggest, a specific ERK 1/2 inhibitor. Shikonin
https://www.mdpi.com/1420-3049/24/19/3542/htm
Gingival mucosa | definition of gingival mucosa by Medical dictionaryGingival mucosa | definition of gingival mucosa by Medical dictionary
Looking for online definition of gingival mucosa in the Medical Dictionary? gingival mucosa explanation free. What is gingival mucosa? Meaning of gingival mucosa medical term. What does gingival mucosa mean?
https://medical-dictionary.thefreedictionary.com/gingival+mucosa
Expression of odontogenic ameloblast-associated and amelotin proteins in the junctional epithelium - Nishio - 2013 -...Expression of odontogenic ameloblast-associated and amelotin proteins in the junctional epithelium - Nishio - 2013 -...
Two novel proteins - odontogenic ameloblast-associated protein and amelotin - have recently been identified in maturation-stage ameloblasts and in the junctional epithelium. This article reviews the structure and function of the junctional epithelium, the pattern of expression of odontogenic ameloblast-associated and amelotin proteins and the potential involvement of these proteins in the formation and regeneration of the junctional epithelium. ...
http://onlinelibrary.wiley.com/doi/10.1111/prd.12031/abstract
Porphyromonas gingivalis invasion of gingival epithelial cells. | Infection and ImmunityPorphyromonas gingivalis invasion of gingival epithelial cells. | Infection and Immunity
Porphyromonas gingivalis, a periodontal pathogen, can invade primary cultures of gingival epithelial cells. Optimal invasion occurred at a relatively low multiplicity of infection (i.e., 100) and demonstrated saturation at a higher multiplicity of infection. Following the lag phase, during which bacteria invaded poorly, invasion was independent of growth phase. P. gingivalis was capable of replicating within the epithelial cells. Invasion was an active process requiring both bacterial and epithelial cell energy production. Invasion was sensitive to inhibitors of microfilaments and microtubules, demonstrating that epithelial cell cytoskeletal rearrangements are involved in bacterial entry. P. gingivalis, but not epithelial cell, protein synthesis was necessary for invasion. Invasion within the epithelial cells was not blocked by inhibitors of protein kinase activity. Invasion was inhibited by protease inhibitors, suggesting that P. gingivalis proteases may be involved in the invasion process. ...
https://iai.asm.org/content/63/10/3878?ijkey=641916c4fcca8edfc5f385665a74620fd17bbec5&keytype2=tf_ipsecsha
Microarray and quantitative RT-PCR analyses in calcium-channel blockers induced gingival overgrowth tissues of periodontitis...Microarray and quantitative RT-PCR analyses in calcium-channel blockers induced gingival overgrowth tissues of periodontitis...
OBJECTIVES The purpose of the present study was to analyse transcriptomes and mRNA expression levels for specific genes in calcium-channel blocker-induced gingival overgrowth (GO) tissues. DESIGN Eight gingival tissues samples (from both GO negative and positive sites) were harvested from four GO patients for microarray analyses. Twelve candidate genes were selected for further quantitative real time reverse transcription-polymerase chain reaction (qRT-PCR) analyses. Ten GO tissues from periodontitis patients and ten control gingival tissues from healthy subjects were compared by qRT-PCR. Mann-Whitney U-test was used for statistical evaluation. RESULTS In GO positive tissues, 163-1631 up-regulated and 100-695 down-regulated genes were identified with more than two-fold changes compared with GO negative tissues amongst patients by microarray experiments. No commonly expressed genes amongst the eight sets of microarray data were found. The clustering analysis confirmed that the entire transcriptome
https://www.semanticscholar.org/paper/Microarray-and-quantitative-RT-PCR-analyses-in-cal-Shimizu-Kubota/c0cf1eb80cafef92ce0913b6ba08e49d66ec5064
Contraction and organization of collagen gels by cells cultured from periodontal ligament, gingiva and bone suggest functional...Contraction and organization of collagen gels by cells cultured from periodontal ligament, gingiva and bone suggest functional...
Monkey periodontal ligament fibroblasts (MPLF cells), human gingival fibroblasts (HGF cells), rat embryonic calvaria cells (REC cells), porcine periodontal ligament epithelial cells (PPLE cells) and rat osteosarcoma 17/2 cells (ROS cells) were incorporated into 3-dimensional collagen gels plated in 60 mm Petri dishes in order: first, to measure the capacity of these cell types to contract; second, to investigate cell-collagen and intercellular relationships during contraction; and third, to define the cellular contribution to tissue contraction in an in vitro system. Measurements at times up to 72 h on 3 ml gels containing 5 × 10(5) cells and with a collagen concentration of 1.20 mg/ml showed that MPLF cells contracted the gels at a significantly greater rate (P less than 0.001) than did the other cell types. In addition, contraction started sooner and was of greater extent than with the other cells. HGF cells contracted the gels more rapidly than REC and PPLE cells, while ROS cells caused no ...
http://jcs.biologists.org/content/50/1/299
The effect of MTAD, an endodontic irrigant, on fibroblast attachment to periodontally affected root surfaces: A SEM analysis ...The effect of MTAD, an endodontic irrigant, on fibroblast attachment to periodontally affected root surfaces: A SEM analysis ...
Background: Root surface debridement (RSD) is necessary to create an environment suitable for reattachment of the periodontium. Root surface conditioning may aid the formation of a biocompatible surface suitable for cell reattachment. BioPure™ MTAD (mixture of Doxycycline, citric acid and a detergent) is an endodontic irrigant with antibacterial properties and the ability to remove smear layer. It was hypothesized that MTAD may be useful for root surface conditioning. The efficacy of MTAD as a conditioner was measured by examining fibroblast attachment to root surfaces. Materials and Methods: Thirty-two specimens of human teeth with advanced periodontal disease were used. The surfaces were root planed until smooth. Half of the specimens were treated with 0.9% saline and the other samples with Biopure MTAD. As a negative control group, five further samples were left unscaled with surface calculus. Human gingival fibroblast cells HGF1-PI1 were cultured and poured over the tooth specimens and ...
http://orca.cf.ac.uk/50751/
Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis - Full Text View -...Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis - Full Text View -...
The etiopathogenesis of periodontal disease results from complex interaction between infectious agents, mainly including bacteria, and host cellular and humoral immune responses. However it is thought that bacteria-induced pathogenesis is not sufficient alone to explain all biological and clinical features of the destructive periodontal disease. The main hypothesis is that herpesviruses, such as Epstein-Barr Virus, may participate as well by altering epithelial gingival cell biology and consequently may promote the initiation and progression of periodontitis ...
https://clinicaltrials.gov/show/NCT01246596
Gingival and Periodontal Pocket | Gingival Periodontal Pocket | Technology TrendsGingival and Periodontal Pocket | Gingival Periodontal Pocket | Technology Trends
Gingival And Periodontal Pocket. Gingival and periodontal pockets are dental terms indicating the presence of an abnormal gingival sulcus near the point at which the gums contact a tooth. ...
http://www.primidi.com/gingival_and_periodontal_pocket
Gingival Graft - Shoaib Khan, DMDGingival Graft - Shoaib Khan, DMD
Arlington Heights oral surgeon, Dr. Khan recommends gingival graft if a build-up of calculus and plaque on the root or if tooth decay has already started.
http://drmskhan.com/services/oral-surgery/gingival-graft/
Evaluation of the distribution of dendritic cells in healthy peri-implant mucosa in comparison to that of healthy gingiva: an...Evaluation of the distribution of dendritic cells in healthy peri-implant mucosa in comparison to that of healthy gingiva: an...
Evaluation of the distribution of dendritic cells in healthy peri-implant mucosa in comparison to that of healthy gingiva: an original research
https://www.ijmedicine.com/index.php/ijam/article/view/2638
Periodontal Disease Stages and Treatment Dublin, Grove City, New Albany, SpringfieldPeriodontal Disease Stages and Treatment Dublin, Grove City, New Albany, Springfield
In the most drastic stage of periodontal disease, the bone and the attachment of the gums to the teeth have been destroyed. This may cause your teeth to shift or loosen and can affect how your teeth come together. You may notice a bad taste or smell in your mouth. Proper dental care must be initiated to save the teeth or they may need to be removed. Professional intervention may involve pocket reduction therapy and bone grafting along with the incorporation of other therapies.. Pocket reduction therapy is required for this form of periodontal disease when the gingival tissues have not resolved after initial treatment or tissue and root therapy. This is usually necessary when gingival tissues have not shrunk enough or when the supporting bone around the teeth has been lost. Since the gum tissue has not shrunk, they provide a greater place for bacteria to live and attack the bone and tissue causing further damage to occur.. Pocket reduction is a periodontal disease therapy that turns or pulls back ...
https://www.stonerperiospecialists.com/types-of-therapy/periodontist-columbus-ohio-periodontal-disease/three-stages-of-periodontal-disease-and-treatment/
Internet Scientific PublicationsInternet Scientific Publications
Periodontitis is a chronic destructive category of periodontal disease that progresses to the resorption of alveolar bone, which leads to progressive bone destruction and tooth loss. As a consequence of resorption, breakdown of products are released into periodontal tissues, migrating toward the gingival sulcus and gathering from the surrounding site in whole saliva, where several of them have been identified. 2930. Among the several host enzymes proposed as diagnostic indicators of periodontal status, ALP was one of the first to be identified. 31 ALP is released from polymorphonuclear cells (PMNs) during inflammation 10 and from osteoblasts 32 and periodontal ligament fibroblasts 33 during bone formation and periodontal regeneration respectively.. ALP activity in serum has been extensively studied, and it was suggested that ALP allows bone mineralization by releasing an organic phosphate that contributes to the deposition of calcium phosphate complexes into the osteoid matrix. 3435 ALP might ...
http://ispub.com/IJDS/8/1/9126
Renamel Gingafill | Cosmedent, Inc.Renamel Gingafill | Cosmedent, Inc.
Quickly simulate missing gingival tissue with Renamel Gingafill. This pink composite is easily placed, readily sculptable and highly polishable. Renamel Gingafill is a great solution for lost gingival tissue, cervical erosions with loss of gingival attachment and reconstruction of lost inter-dental papilla ...
https://www.cosmedent.com/store/item/?utm_source=cosmedent&utm_campaign=viddescription_tag&utm_medium=website&utm_term=microfill&utm_content=CreatingNaturalSmithson&ItemId=3552&DepartmentId=3
Pet Periodontal DiseasePet Periodontal Disease
Periodontal disease occurs when bacteria from the mouth form on the pets teeth in a substance called plaque. The plaque makes its way under the gumline and sets in motion a vicious circle, which can eventually lead to tooth loss for the animal. The bacteria in the subgingival plaque will secrete toxins. These toxins damage the periodontal tissues and can decrease the attachment.. However, the bacteria will also elicit an inflammatory response from the animals gingival tissues. White blood cells and other inflammatory mediators will leak out of the periodontal tissues and into the periodontal space (between the gum or bone and the tooth). The white blood cells will release their enzymes to destroy the bacterial invaders, but will also damage the attachment of the tooth. As this progresses, the pocket will get deeper and deeper. This will weaken the bone in the area, and if it is in the lower jaw it can weaken it to the point of causing a pathologic fracture. This is most common in older small ...
https://www.dogbeachvet.com/our-services/pet-periodontal-disease
Site-Wise Analysis | LISTERINE® ProfessionalSite-Wise Analysis | LISTERINE® Professional
Site-Wise Analysis concluded that adding LISTERINE® Antiseptic result-ed in 2x more healthy gingival sites versus brushing and flossing alone.
https://www.listerineprofessional.ca/scientific-evidence/sitewise-analysis
6520-01-314-2762 Gingival Retraction Cord, Impregnated, Dental6520-01-314-2762 Gingival Retraction Cord, Impregnated, Dental
An item used for retraction of gingival tissues in preparation for taking impressions and setting of crowns or restorations. It controls the bleeding and seepage of tissues during dental procedures. ...
http://dentalinstruments.tpub.com/21/01-314-2762.htm
Frontiers | Pathways that Regulate ROS Scavenging Enzymes, and Their Role in Defense Against Tissue Destruction in...Frontiers | Pathways that Regulate ROS Scavenging Enzymes, and Their Role in Defense Against Tissue Destruction in...
Periodontitis, an inflammatory disease that affects the tissues surrounding the teeth, is a common disease worldwide. It is caused by a dysregulation of the host inflammatory response to bacterial infection, which leads to soft and hard tissue destruction. In particular, it is the excessive inflammation in response to bacterial plaque that leads to the release of reactive oxygen species (ROS) from neutrophils, which, then play a critical role in the destruction of periodontal tissue.Generally, ROS produced from immune cells exhibit an anti-bacterial effect and play a role in host defense and immune regulation. Excessive ROS, however, can exert cytotoxic effects, cause oxidative damage to proteins and DNA, can interfere with cell growth and cell cycle progression, and induce apoptosis of gingival fibroblasts. Collectively, these effects enable ROS to directly induce periodontal tissue damage. Some ROS also act as intracellular signaling molecules during osteoclastogenesis, and can thus also play an
https://www.frontiersin.org/articles/10.3389/fphys.2017.00351/full
Alternatives to gingival graft for gum recession? - DrgumsAlternatives to gingival graft for gum recession? - Drgums
There are some limitations to using cadaver tissue, but it can be done. The laser aids in faster healing. There are no set rules with regard to millimeters.
https://drgums.com/alternatives-gingival-graft-gum-recession/
Blar i Department of Clinical Dentistry på utgivelsesdatoBlar i Department of Clinical Dentistry på utgivelsesdato
Gingival biopsies were obtained from 23 children, aged 5-11 years (8.6 ± 1.8 years). Specimens were taken from areas of the gingiva adjacent to the teeth which were to be extracted because of caries or its sequelae and ...
https://bora.uib.no/bora-xmlui/handle/1956/1014/browse?type=dateissued
Huge Gingival swellingHuge Gingival swelling
A 62 y/o female presented with a very large gingival swelling. She stated that the swelling had been of about 3 months duration. The gingival swelling was in the area of retained roots of tooth 25 measuring 4.2 x 3.4 x 3.7 cm. The patient reported that this swelling impaired her ability to close her mouth and impacted eating but that she was otherwise asymptomatic. There was no pain, bleeding or sensitivity associated with the swelling.
https://curofy.com/discussion/a6c3efafb1e2719c101305d4a2de4cad
P12 - Biofilm Left - Helse UltrasonicP12 - Biofilm Left - Helse Ultrasonic
The P12 Biofilm Left is a left curved insert with a circular surface and rounded tip. It is recommended for subgingival biofilm removal. Compatibility & T
https://cart.helseultrasonic.com/products/p12
P10 - Biofilm Straight - Helse UltrasonicP10 - Biofilm Straight - Helse Ultrasonic
The P10 Biofilm Straight is a long insert with a circular surface and rounded tip. It is recommended for subgingival biofilm removal. Power Settings: 20% Compat
https://cart.helseultrasonic.com/products/p10
Gingival cyst of the newbornGingival cyst of the newborn
A study to assess the effectiveness of Video Assisted Teaching (vat) programme on knowledge regarding management of minor disorders of newborn among primipara mothers in selected phc, Bangalore. Gingival cyst of the newborn ...
http://dentisty.org/category/Dentistry/Gingival_cyst_of_the_newborn/
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Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network | Protocol (Translated to French)Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network | Protocol (Translated to French)
Nous avons établi une technique pour lisolement, la caractérisation phénotypique et lanalyse fonctionnelle des cellules...
https://www.jove.com/video/53736/lisolement-la-caractrisation-et-de-lexamen-fonctionnel-du-rseau-de?language=French
ATCC Products by Tissue - Skin Page 1ATCC Products by Tissue - Skin Page 1
ATCC has a large collection of cell lines derived from skin, representing the normal and diseased tissue of multiple species.
https://www.atcc.org/en/Products/Cells_and_Microorganisms/By_Tissue/Skin.aspx?dsNav=Ro:110,Up:Page_Product_Listing
ATCC Products by Tissue - Skin Page 16ATCC Products by Tissue - Skin Page 16
ATCC has a large collection of cell lines derived from skin, representing the normal and diseased tissue of multiple species.
https://www.atcc.org/en/Products/Cells_and_Microorganisms/By_Tissue/Skin.aspx?dsNav=Ro:40,Ns:P_Product_Name%7C101%7C1%7C
Human toothHuman tooth
Gingiva[edit]. The gingiva ("gums") is the mucosal tissue that overlays the jaws. There are three different types of epithelium ... Given time, plaque can mineralize along the gingiva, forming tartar. The microorganisms that form the biofilm are almost ... Long term use of chlorhexidine, a mouthwash, may encourage extrinsic stain formation near the gingiva on teeth. This is usually ... and gingiva. Of these, cementum is the only one that is a part of a tooth. Periodontal ligaments connect the alveolar bone to ...
https://en.wikipedia.org/wiki/Human_tooth
PeriodontologyPeriodontology
Gingivae[edit]. Normal gingiva may range in color from light coral pink to heavily pigmented. The soft tissues and connective ... Free gingiva[edit]. The tissues that sit above the alveolar bone crest are considered the free gingiva. In healthy periodontium ... Interdental gingiva[edit]. The interdental gingiva takes up the space beneath a tooth contact point, between two adjacent teeth ... The gingivae are categorised into three anatomical groups; the free, attached and the interdental gingiva. Each of the gingival ...
https://en.wikipedia.org/wiki/Periodontics
Index of oral health and dental articlesIndex of oral health and dental articles
Gingiva • Gingival and periodontal pockets • Gingival cyst of the adult • Gingival cyst of the newborn • Gingival enlargement ...
https://en.wikipedia.org/wiki/Index_of_oral_health_and_dental_articles
Gingival fibersGingival fibers
... fibers that extend towards the crest of the gingiva fibers that extend laterally to the outer surface of the gingiva and fibers ... They hold the marginal gingiva against the tooth They provide the marginal gingiva with enough rigidity to withstand the forces ... circular group - these fibers are unique in that they exist entirely within the gingiva and do not contact the tooth ... Itoiz ME, Carranza FA (2002). "The Gingiva". In Newman MG, Takei HH, Carranza FA (eds.). Carranza's Clinical Periodontology ( ...
https://en.wikipedia.org/wiki/Gingival_fibers
Stippling (dentistry)Stippling (dentistry)
The gingiva often possess a textured surface that is referred to as being stippled (engraved points). Stippling only presents ... Itoiz ME, Carranza FA (2002). "The Gingiva". In Newman MG, Takei HH, Carranza FA (eds.). Carranza's Clinical Periodontology ( ... on the attached gingiva bound to underlying alveolar bone, not the freely moveable alveolar mucosaor free gingiva . Stippling ... used to be thought to indicate health, but it has since been shown that smooth gingiva is not an indication of disease, unless ...
https://en.wikipedia.org/wiki/Stippling_(dentistry)
Angularis nigraAngularis nigra
3. Gingiva biotype; thick and thin tissues often respond differently to inflammation and trauma, thin gingiva is more liable to ... 4. Patient's age; the gingiva recede with aging which can cause an open gingival embrasure. 5. Periodontal disease and loss of ...
https://en.wikipedia.org/wiki/Angularis_nigra
Rete pegsRete pegs
In the epithelium of the mouth, the attached gingiva exhibit rete pegs, while the sulcular and junctional epithelia do not. ... Itoiz, ME; Carranza, FA: The Gingiva. In Newman, MG; Takei, HH; Carranza, FA; editors: Carranza's Clinical Periodontology, 9th ...
https://en.wikipedia.org/wiki/Rete_pegs
Clinical attachment lossClinical attachment loss
Itoiz, ME; Carranza, FA: The Gingiva. In Newman, MG; Takei, HH; Carranza, FA; editors: Carranza's Clinical Periodontology, 9th ...
https://en.wikipedia.org/wiki/Clinical_attachment_loss
Inflammatory myofibroblastic tumourInflammatory myofibroblastic tumour
Manohar, B.; Bhuvaneshwari, S. (Jan 2011). "Plasma cell granuloma of gingiva". J Indian Soc Periodontol. 15 (1): 64-6. doi: ...
https://en.wikipedia.org/wiki/Inflammatory_myofibroblastic_tumour
Gum liftGum lift
If the gingiva is fragile. If the location of the base of the pocket is apical to the mucogingival junction. This would cause ... This method provides permanent results, while simple gum contouring may result in relapse or regrowth of the gingiva. Our smile ... Can correct uneven gingival zeniths (the most apical portion of the free gingiva). Can lengthen clinical crown height (which is ... The morphological characteristics of the dentition and gingiva influence a patient's smile greatly. This should be used in ...
https://en.wikipedia.org/wiki/Gum_lift
SurgerySurgery
After completion of surgery, the patient is transferred to the post anesthesia care unit and closely monitored. When the patient is judged to have recovered from the anesthesia, he/she is either transferred to a surgical ward elsewhere in the hospital or discharged home. During the post-operative period, the patient's general function is assessed, the outcome of the procedure is assessed, and the surgical site is checked for signs of infection. There are several risk factors associated with postoperative complications, such as immune deficiency and obesity. Obesity has long been considered a risk factor for adverse post-surgical outcomes. It has been linked to many disorders such as obesity hypoventilation syndrome, atelectasis and pulmonary embolism, adverse cardiovascular effects, and wound healing complications.[11] If removable skin closures are used, they are removed after 7 to 10 days post-operatively, or after healing of the incision is well under way. It is not uncommon for surgical ...
https://en.wikipedia.org/wiki/Resection_
Periodontal diseasePeriodontal disease
The periodontium consists of four tissues: gingiva, or gum tissue, cementum, or outer layer of the roots of teeth, alveolar ... Crich A (June 1932). "Blastomycosis of the Gingiva and Jaw". Canadian Medical Association Journal. 26 (6): 662-5. PMC 402380. ...
https://en.wikipedia.org/wiki/Periodontal_disease
Laser-assisted new attachment procedureLaser-assisted new attachment procedure
Gold, Steven I.; Vilardi, Mario A. (1994). "Pulsed laser beam effects on gingiva". Journal of Clinical Periodontology. 21 (6): ...
https://en.wikipedia.org/wiki/Laser-assisted_new_attachment_procedure
GingivectomyGingivectomy
As a result, this provides a suitable environment for the healing of the gingiva and the physiological contour of the gingiva ... Gingivectomy is a dental procedure in which a dentist or oral surgeon cuts away part of the gums in the mouth (the gingiva). It ... A high smile line displays the entire crown of the tooth and an abundant amount of gingiva. Thus, this procedure can be viewed ... Padbury A, Eber R, Wang HL (May 2003). "Interactions between the gingiva and the margin of restorations". Journal of Clinical ...
https://en.wikipedia.org/wiki/Gingivectomy
Apical foramenApical foramen
Gingiva: ::19. free or interdental ::20. marginal ::21. alveolar :22. Periodontal ligament :23. Alveolar bone 24. Vessels and ...
https://en.wikipedia.org/wiki/Apical_foramen
Glutamate-rich protein 4Glutamate-rich protein 4
2017). "Human gingiva transcriptome during wound healing". J Clin Periodontol. 44 (4): 394-402. doi:10.1111/jcpe.12669. PMID ...
https://en.wikipedia.org/wiki/Glutamate-rich_protein_4
PeriodontologyPeriodontology
The gingivae are categorised into three anatomical groups; the free, attached and the interdental gingiva. Each of the gingival ... The attached gingiva lies between the free gingival line or groove and the mucogingival junction. The attached gingiva ... Normal gingiva may range in color from light coral pink to heavily pigmented. The soft tissues and connective fibres that cover ... Healthy gingiva can be described as stippled, pale or coral pink in Caucasian people, with various degrees of pigmentation in ...
https://en.wikipedia.org/wiki/Periodontology
Smokers melanosisSmoker's melanosis
It is most often seen in the lower labial gingiva of tobacco users. Most easily it is found in Caucasians, due to their lack of ... Hanioka T, Tanaka K, Ojima M, Yuuki K: Association of melanin pigmentation in the gingiva of children with parents who smoke. ... Dose-Response relationship between tobacco consumption and melanin pigmentation in the attached gingiva. Arch Environ Health ... Occurrence and localization in the attached gingiva. Arch Dermatol 1977; 113:1533-1538. https://commons.wikimedia.org/wiki/File ...
https://en.wikipedia.org/wiki/Smoker's_melanosis
Oral pigmentationOral pigmentation
Within a week, the gingiva returns to normal and is fully healed in next few weeks minus the pigmentation. In conclusion, ... Melanotic macules can be found on the buccal mucosa, lip, palate, alveolar ridge and gingiva. Melanotic macules are benign ... Immediately after, slight erythema of the gingiva becomes apparent. Superficial necrosis is observed over the next few days and ... Smoker's Melanosis, benign melanocytic pigmentation of the oral mucosa, most commonly seen in the lower labial gingiva and ...
https://en.wikipedia.org/wiki/Oral_pigmentation
Wolf toothWolf tooth
They may remain completely underneath the gingiva. A good rule that holds true in most cases is: The further forward or rostral ...
https://en.wikipedia.org/wiki/Wolf_tooth
Arterial treeArterial tree
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization ...
https://en.wikipedia.org/wiki/Arterial_tree
Von Willebrand diseaseVon Willebrand disease
The frequency of oral hemorrhage by location in people with deficiency of F VIII and F IX is: gingiva, 64%; dental pulp, 13%; ... The location of oral bleeds was as follows: labial frenum, 60%; tongue, 23%; buccal mucosa, 17% and gingiva and palate, 0.5%. ...
https://en.wikipedia.org/wiki/Von_Willebrand_disease
StomatitisStomatitis
Lesions are located on the buccal mucosa (inside of the cheeks) or on the gingiva (gums). The condition resembles Oral lichen ... Cheilitis, glossitis, gingivitis syndrome; atypical gingivostomatitis, plasma-cell gingivitis, plasmacytosis of gingiva". Oral ...
https://en.wikipedia.org/wiki/Stomatitis
Dental traumaDental trauma
Areas normally affected are lips, buccal mucosa, gingivae, frenum and tongue. The most common injuries are lips and gingivae. ... Gingivae across the fracture line often lacerated. Investigation : Require more than one radiographic view to identify the ... Gingivae lacerations that are small normally heals spontaneously and do not require any intervention. However, this can be one ... Gingivae bleeding especially around the margins may suggest injury to the periodontal ligament of the tooth. ...
https://en.wikipedia.org/wiki/Dental_trauma
Gum depigmentationGum depigmentation
Following laser depigmentation, the gingiva heals by secondary intention. This results in a lighter and more uniform color of ...
https://en.wikipedia.org/wiki/Gum_depigmentation
List of periodontal diseasesList of periodontal diseases
A gingival abscess involves only the gingiva near the marginal gingiva or the interdental papilla. A periodontal abscess ... The early lesion can occupy up to 15% of the connective tissue of the marginal gingiva and up to 60-70% of collagen may be ... Non-plaque-induced gingival disease is an inflammation of the gingiva that does not result from dental plaque, but from other ... Attström R, Graf-de Beer M, Schroeder HE (July 1975). "Clinical and histologic characteristics of normal gingiva in dogs". J. ...
https://en.wikipedia.org/wiki/List_of_periodontal_diseases
Crown lengtheningCrown lengthening
Padbury A, Eber R, Wang HL (May 2003). "Interactions between the gingiva and the margin of restorations". Journal of Clinical ... The flap, incorporating the buccal/ lingual gingiva and alveolar mucosa, then has to be elevated beyond the mucogingival line ... chronic pain chronic inflammation of the gingiva unpredictable loss of alveolar bone In addition to crown lengthening to ...
https://en.wikipedia.org/wiki/Crown_lengthening
Gingival graftingGingival grafting
A lateral pedicle graft, or pedicle graft, takes tissue from the area immediately adjacent to the damaged gingiva. This is not ... In health, the soft tissue immediately around the teeth is keratinized and is referred to as keratinized tissue or gingiva. ... Koller A, Sapra A. "Anatomy, Head and Neck, Oral Gingiva". StatPearls. PMID 32809497. Jati AS, Furquim LZ, Consolaro A (2016 ...
https://en.wikipedia.org/wiki/Gingival_grafting
Desquamative gingivitisDesquamative gingivitis
... desquamative gingivitis extends beyond the marginal gingiva, involving the full width of the gingiva and sometimes the alveolar ... Plasma cell gingivitis is another form of gingivitis which affects both the attached and free gingiva. Caused by various ... Desquamative gingivitis involves lesions of the free and attached gingiva. Unlike plaque-induced inflammation of the gums ( ...
https://en.wikipedia.org/wiki/Desquamative_gingivitis
Gingiva (Gums)Gingiva (Gums)
... Gingiva, commonly called the gum, is the soft tissue that covers and protects the root of the tooth. The gum is ...
https://www.innerbody.com/image_mouth/skel82.html
Effect of glycine powder air-polishing on the gingiva. - PubMed - NCBIEffect of glycine powder air-polishing on the gingiva. - PubMed - NCBI
Effect of glycine powder air-polishing on the gingiva.. Petersilka G1, Faggion CM Jr, Stratmann U, Gerss J, Ehmke B, Haeberlein ...
https://www.ncbi.nlm.nih.gov/pubmed/18294230?dopt=Abstract
Cartilaginous Choristoma of the Gingiva: A Rare Clinical EntityCartilaginous Choristoma of the Gingiva: A Rare Clinical Entity
Tongue is the most frequent location of occurrence in the oral cavity [8]. But, in our case, it involved the lower gingiva ... V. Perrotti, M. Fioroni, C. Rubini, and A. Piattelli, "Cartilaginous choristoma of the gingiva," Oral Oncology Extra, vol. 41, ... Herein we report a case of cartilaginous choristoma in a 54-year-old male who presented with a swelling on right lower gingiva ... Cartilaginous Choristoma of the Gingiva: A Rare Clinical Entity. Ramalingam Suganya,1 Narasimhan Malathi,1 Subramani Vijaya ...
https://www.hindawi.com/journals/crid/2014/246965/
KELAINAN GINGIVAKELAINAN GINGIVA
38 .HIPERPLASI/FIBROTIC GINGIVA • Definisi • Pembesaran gingiva karena bertambahnya sel dan jar. ... Pd gingiva kr proses infl.udem . Texture : stippling berkurang. • Gjl klin. Tidak Sakit. Kr.Gingivitis Kronis • Definisi : Peny ... HIPERTROFI/INFLAMATORY GINGIVA Definisi Bertambahnya ukuran sel ging.. 37 .Gejala Klinis Gusi merah terang& mudah berdarah. ... Ikat pd gingiva. b. Sistemik. Lokal : OH buruk. Jarang (sering kr obat) • Etiologi a. Pemberian obat Peny. ...
https://www.scribd.com/doc/126135364/KELAINAN-GINGIVA
Myofibroma of the Gingiva: A Rare Case Report and Literature ReviewMyofibroma of the Gingiva: A Rare Case Report and Literature Review
... Vaishali Narayen, Syed Afroz Ahmed, Charu Suri, and ... The tongue is most commonly involved (30%) followed by buccal mucosa (20%) and is rarely seen on the gingiva as in this case [3 ... M. Aiki, H. Yoshimura, S. Ohba, S. Kimura, Y. Imamura, and K. Sano, "Rapid growing myofibroma of the gingiva: report of a case ... In the present case, the lesion was found on the posterior gingiva, lingual and distal to 36, a site common to many different ...
https://www.hindawi.com/journals/crid/2015/243894/
Mouth Cancer (Gingiva Fibrosarcoma) in Dogs | PetMDMouth Cancer (Gingiva Fibrosarcoma) in Dogs | PetMD
The most common location for a fibrosarcoma of the the mouth is in the gums (gingiva). ...
https://www.petmd.com/dog/conditions/cancer/c_dg_fibrosarcoma_gingival
Mouth Cancer (Gingiva Fibrosarcoma) in Cats | petMDMouth Cancer (Gingiva Fibrosarcoma) in Cats | petMD
Mouth Cancer (Gingiva Squamous Cell Carcinoma) in Cats. Carcinoma is a type of tissue cancer that is particularly virulent, ... gingiva. Another word for the gums; the membrane around the teeth and the lining of the mouth ... The most common location for a fibrosarcoma of the the mouth is in the gums (gingiva). ...
https://www.petmd.com/cat/conditions/cancer/c_ct_fibrosarcoma_gingival
Endoscopic visualization of the submarginal gingiva dental sulcus and tooth root surfaces. - PubMed - NCBIEndoscopic visualization of the submarginal gingiva dental sulcus and tooth root surfaces. - PubMed - NCBI
Endoscopic visualization of the submarginal gingiva dental sulcus and tooth root surfaces.. Stambaugh RV1, Myers G, Ebling W, ...
https://www.ncbi.nlm.nih.gov/pubmed/11990438?dopt=Abstract
Gingiva Trimmers - FG, 1.6 mm Diameter - Meisinger USA, LLCGingiva Trimmers - FG, 1.6 mm Diameter - Meisinger USA, LLC
Gingiva trimmers are used for the gentle dilatation of the gingiva. They can also be used in areas that are difficult to reach ...
https://www.pattersondental.com/Supplies/ProductFamilyDetails/PIF_56514
The ABCs of veterinary dentistry: G is for gingivaThe ABCs of veterinary dentistry: "G" is for gingiva
Figure 2Attached gingiva. The attached gingiva extends apically from the free gingiva to the alveolar mucosa. It is firmly ... Anatomically, the gingiva is divided into the marginal and attached areas.. Marginal gingiva. The free gingival margin ... Attached gingiva is keratinized to withstand the stress of mastication. The width of the attached gingiva varies in different ... The inner surface (next to the tooth) of the free gingiva forms the gingival wall of the sulcus. The marginal gingiva extends ...
http://veterinarynews.dvm360.com/abcs-veterinary-dentistry-g-gingiva
Buccal gingiva | definition of buccal gingiva by Medical dictionaryBuccal gingiva | definition of buccal gingiva by Medical dictionary
... buccal gingiva explanation free. What is buccal gingiva? Meaning of buccal gingiva medical term. What does buccal gingiva mean? ... Looking for online definition of buccal gingiva in the Medical Dictionary? ... buccal gingiva. buc·cal gin·gi·va. that portion of the gingiva that covers the buccal surfaces of the teeth and alveolar ... A biopsy was then performed on a spreading lesion involving the buccal gingiva in the premolar-molar area of the right mandible ...
http://medical-dictionary.thefreedictionary.com/buccal+gingiva
Pain-pressure threshold in human gingivae.Pain-pressure threshold in human gingivae.
Gingiva / physiology*. Humans. Male. Mandible. Maxilla. Mouth Mucosa / physiology. Pain Measurement / instrumentation, methods ... In 10 subjects, a custom-made algometer was used to apply pressure at a constant rate to 12 sites on the attached gingivae ... This suggests that the pain-pressure threshold may be measured consistently in attached human gingivae. When measurement of ...
http://www.biomedsearch.com/nih/Pain-pressure-threshold-in-human/7581204.html
Cancer Gingiva: Risk FactorsCancer Gingiva: Risk Factors
Another name for Cancer Gingiva is Mouth Cancer. Risk factors for mouth cancer include: * Chewing tobacco * Alcohol use * ... PubMed Cancer Gingiva References *Casiglia J, Woo SB. A comprehensive review of oral cancer. Gen Dent. 2001 Jan-Feb;49(1):72-82 ... Continue to Cancer Gingiva Symptoms Last Updated: Dec 21, 2010 References Authors: Stephen J. Schueler, MD; John H. Beckett, MD ... Cancer Gingiva Risk Factors. Risk factors for mouth cancer include:. * Chewing tobacco ...
http://www.freemd.com/cancer-gingiva/risk-factors.htm
SR Nexco Paste Gingiva 2.5 g G4 | Resins | Ivoclar Vivadent CASR Nexco Paste Gingiva 2.5 g G4 | Resins | Ivoclar Vivadent CA
The SR Nexco Paste Gingiva shades are coordinated with the Ivoclar Vivadent Gingiva concept of IPS InLine system, IPS d.SIGN ... SR Nexco Paste Gingiva Refill 3g. SR Nexco Paste Gingiva 2.5 g G4. ... Thus, gingiva with a lifelike shade effect can be created according to the same diagram with all veneering systems particularly ...
https://www.ivoclarvivadent.com/en_CA/shop/p/Resins/SRNexcoPASTEGingivaRefill3g/p/640470
Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva | ProtocolThree-dimensional Inflammatory Human Tissue Equivalents of Gingiva | Protocol
The goal of the protocol is to build an inflammatory human gingiva model in vitro. This tissue model co-cultivates three types ... seeding the collagen-HGF solution on extracted teeth to form gingiva-tooth complexes and observing how inflammation in gingiva ... The goal of the protocol is to build an inflammatory human gingiva model in vitro. This tissue model co-cultivates three types ... Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva. doi: 10.3791/57157 Published: April 3, 2018 ...
https://www.jove.com/t/57157/three-dimensional-inflammatory-human-tissue-equivalents-of-gingiva
A Safety/Tolerability and Pharmakokinetic Study of Sargramostim Administrated in the Gingiva - Full Text View - ClinicalTrials...A Safety/Tolerability and Pharmakokinetic Study of Sargramostim Administrated in the Gingiva - Full Text View - ClinicalTrials...
A Safety/Tolerability and Pharmakokinetic Study of Sargramostim Administrated in the Gingiva. The safety and scientific ... A Phase I, Open-Label, Single Center, Safety/Tolerability and Pharmacokinetic Study of Leukine® Administrated in the Gingiva as ...
https://clinicaltrials.gov/show/NCT00689143
Image: Malignant melanoma arising from gingiva, dog - Merck Veterinary ManualImage: Malignant melanoma arising from gingiva, dog - Merck Veterinary Manual
Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Manual outside of North America.. ...
http://www.merckvetmanual.com/en-pr/multimedia/image/v11623029
Mesenchymal Stem Cells Derived from Healthy and Diseased Human Gingiva Support Osteogenesis on Electrospun Polycaprolactone...Mesenchymal Stem Cells Derived from Healthy and Diseased Human Gingiva Support Osteogenesis on Electrospun Polycaprolactone...
Gingiva is an integral part of the periodontium and has recently been identified as a source of adult gingiva-derived ... Gingiva is an integral part of the periodontium and has recently been identified as a source of adult gingiva-derived ... Flow cytometry demonstrated cells isolated from healthy and diseased gingiva met the criteria defining mesenchymal stem cells ( ... Mesenchymal Stem Cells Derived from Healthy and Diseased Human Gingiva Support Osteogenesis on Electrospun Polycaprolactone ...
https://pubmed.ncbi.nlm.nih.gov/29360752/
Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva | Protocol (Translated to Hindi)Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva | Protocol (Translated to Hindi)
"प्रोटोकॉल का लक्ष्य इन विट्रो मेंएक भड़काऊ मानव gingiva मॉडल का निर्माण करने के लिए है । यह ऊतक मॉडल सह तीन आयामी परिस्थितियों ... प्रोटोकॉल का लक्ष्य इन विट्रो मेंएक भड़काऊ मानव gingiva मॉडल का निर्माण करने के लिए है । यह ऊतक मॉडल सह तीन आयामी परिस्थितियों ...
https://www.jove.com/v/57157?language=Hindi
Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis - Full Text View -...Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis - Full Text View -...
Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis. The recruitment ...
https://clinicaltrials.gov/show/NCT01246596
Lateral retropharyngeal node metastasis from carcinoma of the upper gingiva and maxillary sinus. | American Journal of...Lateral retropharyngeal node metastasis from carcinoma of the upper gingiva and maxillary sinus. | American Journal of...
Lateral retropharyngeal node metastasis from carcinoma of the upper gingiva and maxillary sinus.. Y Kimura, T Hanazawa, T Sano ... Clinically unsuspected metastases to the lateral retropharyngeal nodes from carcinomas of the upper gingiva or maxillary sinus ... Lateral retropharyngeal node metastasis from carcinoma of the upper gingiva and maxillary sinus. ... Lateral retropharyngeal node metastasis from carcinoma of the upper gingiva and maxillary sinus. ...
http://www.ajnr.org/content/19/7/1221
Bacteremia After the Use of an Oral Irrigation DeviceA Controlled Study in Subjects with Normal-Appearing Gingiva: Comparison...Bacteremia After the Use of an Oral Irrigation DeviceA Controlled Study in Subjects with Normal-Appearing Gingiva: Comparison...
Bacteremia After the Use of an Oral Irrigation Device: A Controlled Study in Subjects with Normal-Appearing Gingiva: Comparison ... Bacteremia After the Use of an Oral Irrigation Device: A Controlled Study in Subjects with Normal-Appearing Gingiva: Comparison ... Eight of 30 persons with normal-appearing gingiva developed bacteremia after using an oral irrigation device. In comparison, ...
http://annals.org/aim/article/688463/bacteremia-after-use-oral-irrigation-device-controlled-study-subjects-normal
Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case reportLateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report
... *Authors: * ... The present study reported a patient with LRPLN metastasis from squamous cell carcinoma of the upper gingiva, who survived for ... Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report. Molecular and ... Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report. Molecular and ...
https://www.spandidos-publications.com/mco/8/1/68
Local Factors Influencing Gingival Health | Anatomy & Histology of the Gingiva and Basic Oral Hygiene | Continuing Education...Local Factors Influencing Gingival Health | Anatomy & Histology of the Gingiva and Basic Oral Hygiene | Continuing Education...
Histology of the Gingiva and Basic Oral Hygiene Continuing Education Course dentalcare.com ... These local factors, in part, contribute to the gingivas inflammatory response. Proper oral hygiene can control many of these ... Anatomy & Histology of the Gingiva and Basic Oral Hygiene. Local Factors Influencing Gingival Health ...
https://www.dentalcare.com/en-us/professional-education/ce-courses/ce103/local-factors-influencing-gingival-health
Localized amyloidosis of the upper gingiva: a case report | springermedizin.deLocalized amyloidosis of the upper gingiva: a case report | springermedizin.de
Localized amyloidosis of the upper gingiva: a case report. Zeitschrift:. Journal of Medical Case Reports > Ausgabe 1/2014 ... Localized amyloidosis of the upper gingiva: a case report Autoren:. Tommaso Bucci Eduardo Bucci Ana Maria Puig Rullan Paolo ... We present the second case of oral amyloidosis arising in the gingiva ever reported, to the best of our knowledge. ... A 73-year-old White Spanish man presented a persistent nodular mass involving his upper gingiva. The lesion was surgically ...
https://www.springermedizin.de/localized-amyloidosis-of-the-upper-gingiva-a-case-report/9650614
marginal gingivamarginal gingiva
Tag Archives: marginal gingiva Types of Mandibular Major Connectors Part 2 Leave a reply ... A 1 mm concavity for the base of the pontic, further apical to the maximal curvature of the adjacent marginal gingiva, is ... Unlike plaque-induced inflammation it is a dusky red colour and extends beyond the marginal gingiva, often to the full width of ... marginal gingiva, prosthetic teeth, removable partial denture on June 21, 2012. by chzechze. Types of pontic Part 2 Leave a ...
http://www.intelligentdental.com/tag/marginal-gingiva/
Gingiva and bone count index | definition of gingiva and bone count index by Medical dictionaryGingiva and bone count index | definition of gingiva and bone count index by Medical dictionary
What is gingiva and bone count index? Meaning of gingiva and bone count index medical term. What does gingiva and bone count ... Looking for online definition of gingiva and bone count index in the Medical Dictionary? gingiva and bone count index ... redirected from gingiva and bone count index). Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia. index. (pl ... index, gingiva and bone count (Dunning-Leach index),. n an index that permits differential recording of both gingival and bone ...
http://medical-dictionary.thefreedictionary.com/gingiva+and+bone+count+index
WO2008062239A1 - Tooth- and gingiva-cleaning construction operating with carbon dioxide originating in situ - Google...WO2008062239A1 - Tooth- and gingiva-cleaning construction operating with carbon dioxide originating in situ - Google...
The invention relates to a tooth- and gingiva-cleaning construction which functions by the use of carbon dioxide; the ... 1. Tooth- and gingiva-cleaning construction with the use of carbon dioxide which consists of a tooth- and gingiva-cleaning tool ... The tooth- and gingiva-cleaning tool itself consists of a handle of 18 cm in length and of a headpiece 3 cm x 1,2 cm x 1,6 cm ... Tooth- and gingiva-cleaning construction operating with carbon dioxide originating in situ Info. Publication number. ...
https://patents.google.com/patent/WO2008062239A1/en
Colon cancer metastasis to the mandibular gingiva with partial occult squamous differentiation: A case report and literature...Colon cancer metastasis to the mandibular gingiva with partial occult squamous differentiation: A case report and literature...
Gingiva. No. Oral to colon, SD. Chemotherapy. Alive, ND. (6). 12. Yang/2014. F/74. Gingiva. Yes. Colon to oral, 2 years later. ... Gingiva. Yes. Colon to oral, 2 years later. Chemotherapy, radiotherapy. Alive. [i] SD, synchronous diagnosis of oral metastasis ... Gingiva. Yes. Colon to oral, 6 months later. None. Died, 6 months later. (15). ... Ren QG, Huang T, Yang SL and Hu JL: Colon cancer metastasis to the mandibular gingiva with partial occult squamous ...
https://www.spandidos-publications.com/10.3892/mco.2016.1102
Gingiva MaskGingiva Mask
NextDent for Ceramill Gingiva Mask Materiale per stampa 3D di parti gengivali di modelli. NextDent Gingiva Mask for Ceramill è ...
https://www.amanngirrbach.com/it/prodotti/materiali-cadcam/resine-3d/gingiva-mask/
GingivitisGumsMarginal gingivaWidth of the attached gingivaBuccalMesenchymalFree gingivaSquamous Cell CarcLesionConnective tissueToothTeeth and the gingivaSurface of the gingivaInflammationMandibleDentalMucosaMucogingival junctionBoneArtificial gingivaMandibular gingivaLingualMaxillaryEpitheliumShadesAnteriorTissueApicalOralIMSEARPeriodontiumHyperplasiaBacterialCollagenAmyloidosisMaxillaShadeHumanEnamelRecessionClinicalMaskUpperGranuloma
Gingivitis10
  • Pada gingiva selama kehamilan (Pregnancy gingivitis). (scribd.com)
  • Photos courtesy of Dr. Jan Bellows) Gingivitis, or inflammation of the gingiva, is the most common disease in dogs and cats. (dvm360.com)
  • A band of red atrophic or eroded mucosa affecting the attached gingiva is known as dequamative gingivitis. (intelligentdental.com)
  • Gingivitis is an infectious inflammation of the gingiva that is caused by the long-term effects of plaque, a bacterial colonization of the teeth and the gingiva. (priaid.ch)
  • Gingivitis is an infectious inflammation occurring in the gingiva. (priaid.ch)
  • Gingivitis is normally the long-term effect of plaque, a bacterially colonized biofilm deposited on the teeth and the gingiva. (priaid.ch)
  • In the presence of gingivitis, people often have symptoms such as bad oral odor and swelling, redness, ulcerations and bleeding on the gingiva. (priaid.ch)
  • For preventive treatment and as a co-adjuvant therapy for paradontal disorders, gingivitis and for strengthening the gingiva in general. (unitedremedies.com)
  • The following report is another case of bilateral symmetrical lymphangioma of the gingiva which occurred in anterior maxillary gingiva as areas of hyperplastic gingivitis. (biomedcentral.com)
  • En español se denomina gingivitis a la inflamación de las encías. (stackexchange.com)
Gums6
  • The most common location for a fibrosarcoma of the the mouth is in the gums (gingiva). (petmd.com)
  • The supporting tissues are known as the periodontium , which includes the gingiva (gums), alveolar bone , cementum , and the periodontal ligament . (wikipedia.org)
  • Gingiva is another word for the gums, or the soft, pink tissue that surrounds and protects the bottom of the teeth where they enter the jawbone. (icoi.org)
  • A:Gingiva is the dental term for gums. (dentalqa.com)
  • Beautifil II Gingiva is available in 5 natural shades variations of pink to easily mimic patient's individual gum aesthetics and restore areas with missing or receded gums, cervical and wedge shaped defects, root caries and to restore/enhance the pink-white aesthetic harmony. (dentestore.com)
  • Often gums .Also called gingiva . (dictionary.com)
Marginal gingiva6
  • The marginal gingiva extends from the free gingival margin to the attached gingiva (Figure 2). (dvm360.com)
  • The gingival sulcus is a shallow space between the marginal gingiva and the tooth. (dvm360.com)
  • A 1 mm concavity for the base of the pontic, further apical to the maximal curvature of the adjacent marginal gingiva, is developed. (intelligentdental.com)
  • Unlike plaque-induced inflammation it is a dusky red colour and extends beyond the marginal gingiva, often to the full width of the attached gingiva and sometimes onto the alveolar mucosa. (intelligentdental.com)
  • In clinical examination clear vesicular asymptomatic lesions were found on the attached and marginal gingiva in canine area. (biomedcentral.com)
  • The gingival fibers accomplish the following tasks: They hold the marginal gingiva against the tooth They provide the marginal gingiva with enough rigidity to withstand the forces of mastication without distorting They serve to stabilize the marginal gingiva by uniting it with both the tissue of the more rigid attached gingiva as well as the cementum layer of the tooth. (wikipedia.org)
Width of the attached gingiva2
  • The width of the attached gingiva varies in different areas of the mouth and is widest at the maxillary canines (Figures 3A and 3B). (dvm360.com)
  • The gingival margin of the tooth, therefore the entire dentogingival complex, moves coronally with a resulting increase in width of the attached gingiva. (dentaldevotee.com)
Buccal10
  • that portion of the gingiva that covers the buccal surfaces of the teeth and alveolar process. (thefreedictionary.com)
  • Peripheral manifestation include the canine area and buccal gingiva around the canine area. (thefreedictionary.com)
  • On intra oral examination there was a solitary swelling with ill-defined borders of size 5x4 centimeter was noted on the right buccal gingiva extending from mesial aspect of 14 to distal aspect of 17 (Figure 2). (thefreedictionary.com)
  • The microscopic analysis was performed on the buccal gingiva of the mandibular right first molar by a single calibrated blind examiner using a light transmission microscope BX51 (Olympus, Melville, NY, USA). (thefreedictionary.com)
  • A biopsy was then performed on a spreading lesion involving the buccal gingiva in the premolar-molar area of the right mandible (Fig 2). (thefreedictionary.com)
  • The palatal and buccal gingiva of the upper anterior region was sutured into position. (thefreedictionary.com)
  • DG is more common in middle-aged to elderly females, is painful, affects the buccal/labial gingiva predominantly. (intelligentdental.com)
  • Hiperaktif melanosit adalah Menghitamnya Warna gingiva, yang benar-benar jinak yang menyebabkan kerugian estetik by Brian_Adytyawa_ It is most frequently found on the gingival or alveolar mucosa, but many cases are also seen on the buccal mucosa. (bpadjogja.info)
  • A 39-year-old male patient presented with a fibrous mass on the attached buccal gingiva of the upper left cuspid teeth. (biomedcentral.com)
  • A fibrous mass on the attached buccal gingiva of the upper left cuspid teeth was seen during the clinical intraoral examination. (biomedcentral.com)
Mesenchymal4
  • Gingiva is an integral part of the periodontium and has recently been identified as a source of adult gingiva-derived mesenchymal stem cells (GMSCs). (nih.gov)
  • Flow cytometry demonstrated cells isolated from healthy and diseased gingiva met the criteria defining mesenchymal stem cells (MSCs). (nih.gov)
  • This study in mice with established collagen-induced arthritis (CIA) was undertaken to determine whether substitution of human gingiva-derived mesenchymal stem cells (G-MSCs) would significantly improve the therapeutic effects. (nih.gov)
  • Human gingiva-derived mesenchymal stem cells (GMSC) have shown anti-inflammatory and immunomodulatory effects on autoimmune and inflammatory diseases. (elsevier.com)
Free gingiva5
  • The inner surface (next to the tooth) of the free gingiva forms the gingival wall of the sulcus. (dvm360.com)
  • The attached gingiva extends apically from the free gingiva to the alveolar mucosa. (dvm360.com)
  • The tissues that sit above the alveolar bone crest are considered the free gingiva. (wikipedia.org)
  • A natural space called the gingival sulcus lies apically to the gingival margin, between the tooth and the free gingiva. (wikipedia.org)
  • [4] [5] The middle or centre part of the interdental papilla is made up of attached gingiva, whereas the borders and tip are formed by the free gingiva. (wikipedia.org)
Squamous Cell Carc2
  • The present study reported a patient with LRPLN metastasis from squamous cell carcinoma of the upper gingiva, who survived for >7 years. (spandidos-publications.com)
  • Alexander Pazoki, D.D.S.,M.D.,F.A.C.S., Director of the Johns Hopkins Division of Oral and Maxillofacial Surgery and Dentistry, and Assistant Professor of Otolaryngology-Head and Neck Surgery, presents the case of a 68-year-old male with squamous cell carcinoma of the left mandible gingiva. (hopkinsmedicine.org)
Lesion2
  • Lymphangioma of the gingiva is a rare lesion that manifest as a pebbly hyperplasia on gingiva. (biomedcentral.com)
  • Bilateral lymphangioma of the gingiva is a very rare lesion which its origin is controversial. (biomedcentral.com)
Connective tissue3
  • This model was obtained through a method of low density seeding epithelialization, from a seeding made up of dissociated human gingiva epithelial cells, of a connective tissue equivalent composed of human fibroblasts included in a collagen gel. (meta.org)
  • Even though this model has less of a differentiation than that of an in vivo gingival epithelium, it does actually reproduce exactly the structures of the human gingiva namely a multilayered epithelium lying on a connective tissue. (meta.org)
  • Some histological and histochemical observations on the connective tissue of chronically inflamed human gingiva. (semanticscholar.org)
Tooth13
  • Gingiva, commonly called the gum, is the soft tissue that covers and protects the root of the tooth. (innerbody.com)
  • Endoscopic visualization of the submarginal gingiva dental sulcus and tooth root surfaces. (nih.gov)
  • The invention relates to a tooth- and gingiva-cleaning construction which develops a vibration motion by the help of the in situ originating carbon dioxide gas in a perforated, from outside roughened membrane which is directly connected with the set of teeth and forms a cleaning tool. (google.com)
  • In the present study, the expression and localization of three basement membrane-specific molecules-laminin 5 (γ2 chain), type IV collagen (α1 chain), and laminin 10 (α5 chain)-and one tooth-specific molecule, amelotin, was analyzed in adult murine gingiva by using in situ hybridization and immunohistochemistry. (springer.com)
  • Clinical examination of her lower anterior teeth revealed tooth surface loss (attrition) and gingival abnormalities, such as recession, ulcerations without destruction of interdental papillae, mild swelling with loss of gingival striping with white diffuse lesions in both free and attached gingivae. (dental-update.co.uk)
  • The attached gingiva dissipates functional and masticatory stresses placed on the gingival tissues during common activities such as mastication, tooth brushing and speaking. (wikipedia.org)
  • The interdental gingiva takes up the space beneath a tooth contact point, between two adjacent teeth. (wikipedia.org)
  • The five Gingiva shades, which can be blended with each other, help to create true-to-nature soft tissue areas characterised by great depth and invisible transitions to the tooth. (niledental.com)
  • The gingiva is attached to the tooth, which forms a seal between the mouth and the underlying bone. (icoi.org)
  • The width of attached gingiva increases with age and in supraerupted teeth, with the wear of the incisal edge and continued tooth eruption. (dentaldevotee.com)
  • Several predisposing conditions may contribute to gingival recession, including a thin alveolar housing, tooth malposition, insufficient supporting alveolar bone, and a deficient amount of attached gingiva, among others. (cdeworld.com)
  • circular group - these fibers are unique in that they exist entirely within the gingiva and do not contact the tooth transseptal group - these fibers have traditionally been described as spanning the interproximal tissue between adjacent teeth, into which they are embedded. (wikipedia.org)
  • However, two other types of fibers have been described in this group: semicircular fibers - fibers that run through the facial and lingual gingiva around each tooth, attaching to the interproximal surfaces of the same tooth. (wikipedia.org)
Teeth and the gingiva1
  • The suitable cleaning of the oral cavity and within it firstly the teeth and the gingiva is a problem equal in age with the humanity since the failure of the oral hygiene can be accompanied with pain and suffering as well as with digestive anomalies. (google.com)
Surface of the gingiva1
  • There are three groups within which gingival fibers are arranged: dentogingival group - there are three types of fibers within this group: fibers that extend towards the crest of the gingiva fibers that extend laterally to the outer surface of the gingiva and fibers that extend outward, past the height of the alveolar crest, and then downward along the cortex of the alveolar bone. (wikipedia.org)
Inflammation2
  • Inflammation in gingiva is the fundamental physiopathology of periodontal diseases. (jove.com)
  • Both plaque and tartar can irritate the gingiva and lead to inflammation. (priaid.ch)
Mandible1
  • Most peripheral calcifying cystic odontogenic tumors are located in the anterior gingiva of the mandible or maxilla. (biomedcentral.com)
Dental3
  • Gingiva resin was created following the close collaboration with dentistry professionals and the dental prosthetists. (funtodo.eu)
  • Mandibles of 4-month-old and 14- to 18-month-old freshly slaughtered steers were utilized to quantitate the immunoglobulin content of the dental pulp and gingiva. (nyu.edu)
  • The steer provided an animal model system for the study of immunoglobulin levels in normal dental pulp and gingiva. (nyu.edu)
Mucosa5
  • The gingiva, or gum, is the keratinized oral mucosa covering the alveolar processes of the jaws, encircling the necks of erupted teeth (Figure 1). (dvm360.com)
  • The attached gingiva meets with the loose alveolar mucosa at the mucogingival junction, also referred as the mucogingival line. (dvm360.com)
  • Gingiva is the soft tissue covering that surrounds the teeth consisting of fibrous tissue which is continuous with the periodontial ligament and the mucosa covering the teeth. (juniordentist.com)
  • Gingiva is the soft tissue around the teeth which is continous with the Mucosa of the Oral cavity, this junction is called the mucogingival junction. (juniordentist.com)
  • It is Differentiated by the line seen in the image which demarcates it due the dark color of the mucosa (due to high vasculature) and the light color of the gingiva (due to presence of more fibers) comparitively. (juniordentist.com)
Mucogingival junction5
  • The mucogingival junction remains stationary throughout life, although the gingiva around it may change in height because of attachment loss. (dvm360.com)
  • It is a stratified squamous keratinizing epithelium, that lines the vestibular and oral surfaces of the gingiva it extends from the mucogingival junction to the gingival epithelium except for the palatal epithelium where it blends with the palatal epithelium. (juniordentist.com)
  • [5] [6] The attached gingiva lies between the free gingival line or groove and the mucogingival junction. (wikipedia.org)
  • Because the mucogingival junction remains stationary throughout adult life, changes in the width of attached gingiva are caused by the modification in the position of the coronal end. (dentaldevotee.com)
  • Epinephrine could evoke intense vasoconstriction propagating to the mucogingival junction, indicating the presence of spreading vasoconstriction in the human gingiva. (biomedcentral.com)
Bone2
  • The soft tissues and connective fibres that cover and protect the underlying cementum, periodontal ligament and alveolar bone are known as the gingivae. (wikipedia.org)
  • [4] Collagen fibres bind the attached gingiva tightly to the underlying periodontium including the cementum and alveolar bone and varies in length and width, [4] depending on the location in the oral cavity and on the individual. (wikipedia.org)
Artificial gingiva9
  • The construction of Artificial gingiva begins by making an impression of labial surface of the bridge and ridge of the patient. (denturesaffordable.com)
  • Wax up of artificial gingiva. (denturesaffordable.com)
  • After excellent esthetics is attained, the wax artificial gingiva will be prepared for processing. (denturesaffordable.com)
  • Artificial gingiva is usually processed from 8 to 10 hours. (denturesaffordable.com)
  • Processed artificial gingiva. (denturesaffordable.com)
  • Artificial gingiva after trimming and polishing. (denturesaffordable.com)
  • Objectives: The aim of this study is to evaluate the effects of three different retraction agents on the color of dentin and artificial gingiva following the gingival retraction. (journalijdr.com)
  • Following the removal of the waxes, 3 mm artificial gingiva was created by a silicone material. (journalijdr.com)
  • After the calculation of ΔE values, the discoloration of the dentine and artificial gingiva was determined. (journalijdr.com)
Mandibular gingiva1
  • Metastatic lung malignancy to mandibular gingiva. (bvsalud.org)
Lingual2
  • Clinical examination revealed a solitary, well defined, soft tissue growth on the posterior gingiva measuring about 2.5 1.5 cm, extending from the lingual and distal aspect of 36 to posteriorly 1 cm short of the anterior border of the ramus. (hindawi.com)
  • This case report describes an unusual presentation of solitary neurofibroma on the lingual gingiva of the mandibular posterior region of a 22-year-old woman. (agd.org)
Maxillary5
  • The gingiva above the maxillary incisors and canines in a dog. (dvm360.com)
  • Lateral retropharyngeal node metastasis from carcinoma of the upper gingiva and maxillary sinus. (ajnr.org)
  • Clinically unsuspected metastases to the lateral retropharyngeal nodes from carcinomas of the upper gingiva or maxillary sinus were found in five patients on follow-up CT examinations. (ajnr.org)
  • Authors report a rare case of a peripheral calcifying cystic odontogenic tumor of the maxillary gingiva. (biomedcentral.com)
  • The mean values of attached gingiva varied in different areas of the mouth with greatest width in maxillary central incisors and least in mandibular molars. (who.int)
Epithelium5
  • The oral epithelium, also called the outer gingival epithelium, is a keratinized or para-keratinized covering of the oral surface of the attached gingiva and gingival papillae. (dvm360.com)
  • This is the epithelium which covers the gingiva present in the sulcus depths. (juniordentist.com)
  • The gingiva is covered with Keratinized Stratified squamous epithelium the outer most layer of gingiva. (juniordentist.com)
  • The outer layers of the epithelium are keratinized and are stratified so the size of the cells increases as we go into the gingiva. (juniordentist.com)
  • it begins at the gingival margin and ends at the base of the sulcus where the junctional epithelium and attached gingiva begins. (wikipedia.org)
Shades3
  • The SR Nexco Paste Gingiva shades are coordinated with the Ivoclar Vivadent Gingiva concept of IPS InLine system, IPS d.SIGN and IPS e.max. (ivoclarvivadent.com)
  • Inclusion of nanofillers and specially modified sub-micron multifunctional organic and glass fillers impart Beautifil II Enamel and Gingiva with exceptional handling characteristics, high abrasion/wear resistance, stable shades, effortless and superior polishability with sustained polish retention for lasting aesthetics. (dentestore.com)
  • Highly aesthetic light-curing restorative in gingiva shades. (dentbay.com)
Anterior2
  • The gingiva shapers come in two different designs, concave anterior and concave posterior, to cope with the most varied indications. (sic-invent.com)
  • The high labial frenal attachment in mandibular anterior segment is most commonly associated with inadequate width of attached gingiva. (who.int)
Tissue5
  • This case report describes a rare benign tumor, which presented as a soft tissue swelling on posterior gingiva. (hindawi.com)
  • Here, we present a detailed protocol for reconstructing human inflammatory tissue equivalents of gingiva (iGTE) in vitro . (jove.com)
  • We first build human tissue equivalents of gingiva (GTE) by utilizing two types of human cells, including human gingival fibroblasts (HGF) and human skin epidermal keratinocytes (HaCaT), under three-dimensional conditions. (jove.com)
  • Here, 3D inflammatory human tissue equivalents of gingiva (iGTE) are established to represent periodontal diseases in vitro . (jove.com)
  • 11,14 Instead, FGGs aim to increase the strength of the soft tissue for resistance against future recession by increasing not only the vertical dimension of the gingiva, but more importantly, its horizontal thickness. (cdeworld.com)
Apical2
  • In 10 subjects, a custom-made algometer was used to apply pressure at a constant rate to 12 sites on the attached gingivae apical to teeth 11 to 16 and 41 to 46. (biomedsearch.com)
  • Defined as exposure of the root surface at the gingival margin, gingival recession is an apical shift in the position of the gingiva secondary to loss of attachment that can negatively affect smile esthetics, increase susceptibility to root caries, and lead to dentin hypersensitivity. (cdeworld.com)
Oral7
  • Eight of 30 persons with normal-appearing gingiva developed bacteremia after using an oral irrigation device. (annals.org)
  • We present the second case of oral amyloidosis arising in the gingiva ever reported, to the best of our knowledge. (springermedizin.de)
  • A clinical and fine needle aspiration cytology study of gingiva in acute leukemia background oral manifestations are frequently the initial signs of acute leukemia prompting the patient to consult the dentist first. (salonmazal.org)
  • Since plaque and tartar can bring a lot of bacteria to the gingiva, an infection may occur even though the bacteria are considered to be part of the normal oral flora. (priaid.ch)
  • Soft gingivae with 32 screw-retained teeth with an oral cavity cover attached. (dentalmartsales.com)
  • Insufficient attached gingiva contributed to the difficulty in oral hygiene maintenance and ultimately poor gingival health. (who.int)
  • Clinical relevance Inadequate width of keratinised gingiva contributed to the difficulty in oral hygiene maintenance and ultimately poor gingival health. (who.int)
IMSEAR1
  • IMSEAR at SEARO: Width of attached gingiva in an Indian population: A descriptive study. (who.int)
Periodontium1
  • Objectives: Attached gingiva is important for maintaining periodontium in a healthy state. (who.int)
Hyperplasia1
  • A 32-year-old man was presented with bilateral hyperplasia of gingiva in upper canine regions. (biomedcentral.com)
Bacterial1
  • Immunohistological study on infiltration of periodontopathic bacterial lipopolysaccharide into gingiva and lesional lymph node. (nii.ac.jp)
Collagen1
  • Weak and sporadic expression of type IV collagen in addition to laminin 10 in the gingiva indicates that these molecules undergo turnover less frequently in adult animals. (springer.com)
Amyloidosis1
  • Localized amyloidosis of the gingiva is an extremely rare condition that seems to show no clinically distinct feature. (springermedizin.de)
Maxilla1
  • A cat's right maxilla (arrows = attached gingiva). (dvm360.com)
Shade2
  • Thus, gingiva with a lifelike shade effect can be created according to the same diagram with all veneering systems particularly in implant superstructures. (ivoclarvivadent.com)
  • Further studies are needed to create more reliable color gingiva shade guide with a large number of patients and different races and places. (eastjmed.org)
Human7
  • Pain-pressure threshold in human gingivae. (biomedsearch.com)
  • This suggests that the pain-pressure threshold may be measured consistently in attached human gingivae. (biomedsearch.com)
  • The goal of the protocol is to build an inflammatory human gingiva model in vitro . (jove.com)
  • IGTE is the first in vitro model of inflammatory gingiva using human cells with a three-dimensional architecture. (jove.com)
  • The aim of this study is to evaluate the effects of lovastatin on the cell viability and osteogenic differentiation of human gingiva-derived stem cells. (alliedacademies.org)
  • A model of human gingiva to be used in pharmacological, basic and clinical research was performed in vitro. (meta.org)
  • This trial was registered in ClinicalTrials.gov titled as Evidence of Spreading Vasoconstriction in Human Gingiva with the reference number of NCT04131283 on 16 October 2019. (biomedcentral.com)
Enamel2
  • Beautifil II Enamel and Gingiva are developed as a complementary line extension of Beautifil II for direct aesthetic restoration. (dentestore.com)
  • Beautifil II Enamel & Gingiva come in a special, one push syringe for controlled dispensing of the material that itself has a smooth, creamy consistency and long working time to easily sculpt fine details and recreate the variety of surface textures seen in natural teeth. (dentestore.com)
Recession2
  • Because each therapy is characterized by the type of grafting material used, the manner in which the grafting material is harvested, and the respective technique for placing the grafting material, understanding their differences will benefit dentists when determining the most appropriate treatment for patients who present with gingival recession and areas of deficient attached gingiva. (cdeworld.com)
  • Understanding the differences among the therapies will benefit dentists when determining the most appropriate treatment for patients who present with gingival recession and areas of deficient attached gingiva. (cdeworld.com)
Clinical1
  • The diagnostic workup led to the diagnosis of an unusual OFM with the clinical presentation involving the gingiva and hard palate. (usp.br)
Mask1
  • NextDent Gingiva Mask is a flexible material that can be used in combination with a model material. (envisiontec.com)
Upper1
  • A 73-year-old White Spanish man presented a persistent nodular mass involving his upper gingiva. (springermedizin.de)
Granuloma1
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