AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth Care
GenomicsDatabases, GeneticComputational BiologyGenome, BacterialGenomeSequence Analysis, DNAPhylogenyEvolution, MolecularGenome, PlantSoftwareGene Expression ProfilingInternetExpressed Sequence TagsUser-Computer InterfaceOligonucleotide Array Sequence AnalysisMolecular Sequence AnnotationSyntenyGenome, HumanChromosome MappingProteomicsMolecular Sequence DataSequence AlignmentDatabases, Nucleic AcidGenome, FungalAlgorithmsIndividualized MedicineMetagenomicsGenetic VariationInformation Storage and RetrievalDatabase Management SystemsModels, GeneticHigh-Throughput Nucleotide SequencingGenetic ResearchMultigene FamilyDatabases, ProteinGenetics, MedicalQuantitative Trait LociSpecies SpecificityContig MappingChromosomes, Artificial, BacterialConserved SequencePharmacogeneticsBase SequenceGenes, PlantGenome, InsectComputer GraphicsGene LibraryGeneticsCluster AnalysisProteinsPhenotypeProteomePolymorphism, Single NucleotideGene Regulatory NetworksSystems BiologyGenome, ArchaealGene OrderGenome, HelminthTranscriptomeComparative Genomic HybridizationSystems IntegrationBiological EvolutionGene DuplicationOryza sativaGenome, ProtozoanMetabolic Networks and PathwaysMicrobiologySequence Analysis, ProteinGene Transfer, HorizontalGenetic MarkersAmino Acid SequenceGenetic PrivacyDatabases, FactualGenome-Wide Association StudyCrops, AgriculturalDNA, PlantPhysical Chromosome MappingChromosomes, PlantNutrigenomicsBiotechnologyBacterial ProteinsNational Human Genome Research Institute (U.S.)Genetic TestingGenetic TechniquesStructural Homology, ProteinSorghumBacteriaAdaptation, BiologicalResearchToxicogeneticsData MiningGene Expression RegulationMetabolomicsPlantsOpen Reading FramesMolecular BiologyArabidopsis
Genomics
The systematic study of the complete DNA sequences (GENOME) of organisms.
Databases, Genetic
Databases devoted to knowledge about specific genes and gene products.
Computational Biology
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
Genome, Bacterial
The genetic complement of a BACTERIA as represented in its DNA.
Genome
The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.
Sequence Analysis, DNA
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Phylogeny
The relationships of groups of organisms as reflected by their genetic makeup.
Evolution, Molecular
The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.
Genome, Plant
The genetic complement of a plant (PLANTS) as represented in its DNA.
Software
Sequential operating programs and data which instruct the functioning of a digital computer.
Gene Expression Profiling
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
Internet
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Expressed Sequence Tags
Partial cDNA (DNA, COMPLEMENTARY) sequences that are unique to the cDNAs from which they were derived.
User-Computer Interface
The portion of an interactive computer program that issues messages to and receives commands from a user.
Oligonucleotide Array Sequence Analysis
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
Molecular Sequence Annotation
The addition of descriptive information about the function or structure of a molecular sequence to its MOLECULAR SEQUENCE DATA record.
Synteny
The presence of two or more genetic loci on the same chromosome. Extensions of this original definition refer to the similarity in content and organization between chromosomes, of different species for example.
Genome, Human
The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.
Chromosome Mapping
Any method used for determining the location of and relative distances between genes on a chromosome.
Proteomics
The systematic study of the complete complement of proteins (PROTEOME) of organisms.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Sequence Alignment
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Databases, Nucleic Acid
Databases containing information about NUCLEIC ACIDS such as BASE SEQUENCE; SNPS; NUCLEIC ACID CONFORMATION; and other properties. Information about the DNA fragments kept in a GENE LIBRARY or GENOMIC LIBRARY is often maintained in DNA databases.
Genome, Fungal
The complete gene complement contained in a set of chromosomes in a fungus.
Algorithms
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Individualized Medicine
Therapeutic approach tailoring therapy for genetically defined subgroups of patients.
Metagenomics
The genomic analysis of assemblages of organisms.
Genetic Variation
Genotypic differences observed among individuals in a population.
Information Storage and Retrieval
Organized activities related to the storage, location, search, and retrieval of information.
Database Management Systems
Software designed to store, manipulate, manage, and control data for specific uses.
Models, Genetic
Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
High-Throughput Nucleotide Sequencing
Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.
Genetic Research
Research into the cause, transmission, amelioration, elimination, or enhancement of inherited disorders and traits.
Multigene Family
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Databases, Protein
Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.
Genetics, Medical
A subdiscipline of human genetics which entails the reliable prediction of certain human disorders as a function of the lineage and/or genetic makeup of an individual or of any two parents or potential parents.
Quantitative Trait Loci
Genetic loci associated with a QUANTITATIVE TRAIT.
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Contig Mapping
Overlapping of cloned or sequenced DNA to construct a continuous region of a gene, chromosome or genome.
Chromosomes, Artificial, Bacterial
DNA constructs that are composed of, at least, a REPLICATION ORIGIN, for successful replication, propagation to and maintenance as an extra chromosome in bacteria. In addition, they can carry large amounts (about 200 kilobases) of other sequence for a variety of bioengineering purposes.
Conserved Sequence
A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.
Pharmacogenetics
A branch of genetics which deals with the genetic variability in individual responses to drugs and drug metabolism (BIOTRANSFORMATION).
Base Sequence
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Genes, Plant
The functional hereditary units of PLANTS.
Genome, Insect
The genetic complement of an insect (INSECTS) as represented in its DNA.
Computer Graphics
The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.
Gene Library
A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.
Genetics
The branch of science concerned with the means and consequences of transmission and generation of the components of biological inheritance. (Stedman, 26th ed)
Cluster Analysis
A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.
Proteins
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Phenotype
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Proteome
The protein complement of an organism coded for by its genome.
Polymorphism, Single Nucleotide
A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.
Gene Regulatory Networks
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
Systems Biology
Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.
Genome, Archaeal
The genetic complement of an archaeal organism (ARCHAEA) as represented in its DNA.
Gene Order
The sequential location of genes on a chromosome.
Genome, Helminth
The genetic complement of a helminth (HELMINTHS) as represented in its DNA.
Transcriptome
The pattern of GENE EXPRESSION at the level of genetic transcription in a specific organism or under specific circumstances in specific cells.
Comparative Genomic Hybridization
A method for comparing two sets of chromosomal DNA by analyzing differences in the copy number and location of specific sequences. It is used to look for large sequence changes such as deletions, duplications, amplifications, or translocations.
Systems Integration
The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Biological Evolution
The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.
Gene Duplication
Processes occurring in various organisms by which new genes are copied. Gene duplication may result in a MULTIGENE FAMILY; supergenes or PSEUDOGENES.
Oryza sativa
Annual cereal grass of the family POACEAE and its edible starchy grain, rice, which is the staple food of roughly one-half of the world's population.
Genome, Protozoan
The complete genetic complement contained in a set of CHROMOSOMES in a protozoan.
Metabolic Networks and Pathways
Complex sets of enzymatic reactions connected to each other via their product and substrate metabolites.
Microbiology
The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.
Sequence Analysis, Protein
A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.
Gene Transfer, Horizontal
The naturally occurring transmission of genetic information between organisms, related or unrelated, circumventing parent-to-offspring transmission. Horizontal gene transfer may occur via a variety of naturally occurring processes such as GENETIC CONJUGATION; GENETIC TRANSDUCTION; and TRANSFECTION. It may result in a change of the recipient organism's genetic composition (TRANSFORMATION, GENETIC).
Genetic Markers
A phenotypically recognizable genetic trait which can be used to identify a genetic locus, a linkage group, or a recombination event.
Amino Acid Sequence
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Genetic Privacy
The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.
Databases, Factual
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
Genome-Wide Association Study
An analysis comparing the allele frequencies of all available (or a whole GENOME representative set of) polymorphic markers in unrelated patients with a specific symptom or disease condition, and those of healthy controls to identify markers associated with a specific disease or condition.
Crops, Agricultural
Cultivated plants or agricultural produce such as grain, vegetables, or fruit. (From American Heritage Dictionary, 1982)
DNA, Plant
Deoxyribonucleic acid that makes up the genetic material of plants.
Physical Chromosome Mapping
Mapping of the linear order of genes on a chromosome with units indicating their distances by using methods other than genetic recombination. These methods include nucleotide sequencing, overlapping deletions in polytene chromosomes, and electron micrography of heteroduplex DNA. (From King & Stansfield, A Dictionary of Genetics, 5th ed)
Chromosomes, Plant
Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of PLANTS.
Nutrigenomics
The study of the relationship between NUTRITIONAL PHYSIOLOGY and genetic makeup. It includes the effect of different food components on GENE EXPRESSION and how variations in GENES effect responses to food components.
Biotechnology
Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.
Bacterial Proteins
Proteins found in any species of bacterium.
National Human Genome Research Institute (U.S.)
Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports research into the mapping of the human genome and other organism genomes. The National Center for Human Genome Research was established in 1989 and re-named the National Human Genome Research Institute in 1997.
Genetic Testing
Detection of a MUTATION; GENOTYPE; KARYOTYPE; or specific ALLELES associated with genetic traits, heritable diseases, or predisposition to a disease, or that may lead to the disease in descendants. It includes prenatal genetic testing.
Genetic Techniques
Chromosomal, biochemical, intracellular, and other methods used in the study of genetics.
Structural Homology, Protein
The degree of 3-dimensional shape similarity between proteins. It can be an indication of distant AMINO ACID SEQUENCE HOMOLOGY and used for rational DRUG DESIGN.
Sorghum
A plant genus of the family POACEAE. The grain is used for FOOD and for ANIMAL FEED. This should not be confused with KAFFIR LIME or with KEFIR milk product.
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Adaptation, Biological
Changes in biological features that help an organism cope with its ENVIRONMENT. These changes include physiological (ADAPTATION, PHYSIOLOGICAL), phenotypic and genetic changes.
Research
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Toxicogenetics
The study of existing genetic knowledge, and the generation of new genetic data, to understand and thus avoid DRUG TOXICITY and adverse effects from toxic substances from the environment.
Data Mining
Use of sophisticated analysis tools to sort through, organize, examine, and combine large sets of information.
Gene Expression Regulation
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Metabolomics
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
Plants
Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.
Open Reading Frames
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
Molecular Biology
A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules.
Arabidopsis
A plant genus of the family BRASSICACEAE that contains ARABIDOPSIS PROTEINS and MADS DOMAIN PROTEINS. The species A. thaliana is used for experiments in classical plant genetics as well as molecular genetic studies in plant physiology, biochemistry, and development.

Analysis of flanking sequences from dissociation insertion lines: a database for reverse genetics in Arabidopsis. (1/10766)

We have generated Dissociation (Ds) element insertions throughout the Arabidopsis genome as a means of random mutagenesis. Here, we present the molecular analysis of genomic sequences that flank the Ds insertions of 931 independent transposant lines. Flanking sequences from 511 lines proved to be identical or homologous to DNA or protein sequences in public databases, and disruptions within known or putative genes were indicated for 354 lines. Because a significant portion (45%) of the insertions occurred within sequences defined by GenBank BAC and P1 clones, we were able to assess the distribution of Ds insertions throughout the genome. We discovered a significant preference for Ds transposition to the regions adjacent to nucleolus organizer regions on chromosomes 2 and 4. Otherwise, the mapped insertions appeared to be evenly dispersed throughout the genome. For any given gene, insertions preferentially occurred at the 5' end, although disruption was clearly possible at any intragenic position. The insertion sites of >500 lines that could be characterized by reference to public databases are presented in a tabular format at http://www.plantcell. org/cgi/content/full/11/12/2263/DC1. This database should be of value to researchers using reverse genetics approaches to determine gene function.  (+info)

Microbial genomics: from sequence to function. (2/10766)

The era of genomics (the study of genes and their function) began a scant dozen years ago with a suggestion by James Watson that the complete DNA sequence of the human genome be determined. Since that time, the human genome project has attracted a great deal of attention in the scientific world and the general media; the scope of the sequencing effort, and the extraordinary value that it will provide, has served to mask the enormous progress in sequencing other genomes. Microbial genome sequencing, of particular interest to the community studying emerging infectious diseases, prompted the series of articles presented in the following pages. These articles review technological and scientific advances that have occurred since publication of the Haemophilus influenzae genome sequence in July 1995; that was the first demonstration that an entire genome sequence could be deciphered by a "shotgun" approach, i.e., the sequencing and assembly of random fragments of the genome. This is now the method of choice for sequencing of most other genomes, including human (as performed by Celera Genomics).  (+info)

Genomics and bacterial pathogenesis. (3/10766)

Whole-genome sequencing is transforming the study of pathogenic bacteria. Searches for single virulence genes can now be performed on a genomewide scale by a variety of computer and genetic techniques. These techniques are discussed to provide a perspective on the developing field of genomics.  (+info)

Comparative genomics and understanding of microbial biology. (4/10766)

The sequences of close to 30 microbial genomes have been completed during the past 5 years, and the sequences of more than 100 genomes should be completed in the next 2 to 4 years. Soon, completed microbial genome sequences will represent a collection of >200,000 predicted coding sequences. While analysis of a single genome provides tremendous biological insights on any given organism, comparative analysis of multiple genomes provides substantially more information on the physiology and evolution of microbial species and expands our ability to better assign putative function to predicted coding sequences.  (+info)

Using DNA microarrays to study host-microbe interactions. (5/10766)

Complete genomic sequences of microbial pathogens and hosts offer sophisticated new strategies for studying host-pathogen interactions. DNA microarrays exploit primary sequence data to measure transcript levels and detect sequence polymorphisms, for every gene, simultaneously. The design and construction of a DNA microarray for any given microbial genome are straightforward. By monitoring microbial gene expression, one can predict the functions of uncharacterized genes, probe the physiologic adaptations made under various environmental conditions, identify virulence-associated genes, and test the effects of drugs. Similarly, by using host gene microarrays, one can explore host response at the level of gene expression and provide a molecular description of the events that follow infection. Host profiling might also identify gene expression signatures unique for each pathogen, thus providing a novel tool for diagnosis, prognosis, and clinical management of infectious disease.  (+info)

Automatic detection of conserved gene clusters in multiple genomes by graph comparison and P-quasi grouping. (6/10766)

We previously reported two graph algorithms for analysis of genomic information: a graph comparison algorithm to detect locally similar regions called correlated clusters and an algorithm to find a graph feature called P-quasi complete linkage. Based on these algorithms we have developed an automatic procedure to detect conserved gene clusters and align orthologous gene orders in multiple genomes. In the first step, the graph comparison is applied to pairwise genome comparisons, where the genome is considered as a one-dimensionally connected graph with genes as its nodes, and correlated clusters of genes that share sequence similarities are identified. In the next step, the P-quasi complete linkage analysis is applied to grouping of related clusters and conserved gene clusters in multiple genomes are identified. In the last step, orthologous relations of genes are established among each conserved cluster. We analyzed 17 completely sequenced microbial genomes and obtained 2313 clusters when the completeness parameter P: was 40%. About one quarter contained at least two genes that appeared in the metabolic and regulatory pathways in the KEGG database. This collection of conserved gene clusters is used to refine and augment ortholog group tables in KEGG and also to define ortholog identifiers as an extension of EC numbers.  (+info)

The gene guessing game. (7/10766)

A recent flurry of publications and media attention has revived interest in the question of how many genes exist in the human genome. Here, I review the estimates and use genomic sequence data from human chromosomes 21 and 22 to establish my own prediction.  (+info)

Featured organism: Danio rerio, the zebrafish. (8/10766)

The zebrafish has long been a favourite model for the study of vertebrate development. Here we provide an overview of the current state of knowledge and resources for the study of this fish, with comments on the future direction of zebrafish genomics from Professor Mark Fishman and Dr Stephen Wilson.  (+info)

New preprint server for the health sciences announced today - Cold Spring Harbor LaboratoryNew preprint server for the health sciences announced today - Cold Spring Harbor Laboratory
medRxiv aims to meet the unique preprint needs of the clinical research community with a free, non-profit service.. Cold Spring Harbor, NY, New Haven, CT, and London, UK - Cold Spring Harbor Laboratory (CSHL), Yale University, and BMJ today announced the forthcoming launch of medRxiv (pronounced med-archive), a free online archive and distribution service for preprints in the medical and health sciences.. medRxiv is expected to begin accepting manuscripts on June 6th and will be overseen by the three organizations.. Preprints are preliminary versions of research articles that researchers share with each other before they are published in a journal, to enhance dissemination of study methods and findings among the scientific community and to solicit feedback to help improve the final published article. medRxivs founding organizations are Cold Spring Harbor Laboratory, creator of the biological preprint server bioRxiv (launched in 2013); BMJ, publisher of leading peer-reviewed journals and ...
https://www.cshl.edu/new-preprint-server-for-the-health-sciences-announced-today/
Research may explain how the bodys foremost anti-cancer guardian protein learned to switch sides - Cold Spring Harbor...Research may explain how the bodys foremost anti-cancer guardian protein learned to switch sides - Cold Spring Harbor...
Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new function of the bodys most important tumor-suppressing protein.. Cold Spring Harbor, NY - Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new function of the bodys most important tumor-suppressing protein. Called p53, this protein has been called the guardian of the genome. It normally comes to the fore when healthy cells sense damage to their DNA caused by stress, such as exposure to toxic chemicals or intense exposure to the suns UV rays. If the damage is severe, p53 can cause a cell to commit preprogrammed cell-death, or apoptosis. Mutant versions of p53 that no longer perform this vital function, on the other hand, are enablers of many different cancers.. Cancer researcher Dr. Raffaella Sordella, a CSHL Associate Professor, and colleagues, today report in Proceedings of the National Academy of Sciences the discovery of a p53 cousin they call p53Ψ (the Greek letter psi). It is a previously ...
https://www.cshl.edu/research-may-explain-how-the-body-s-foremost-anti-cancer-guardian-protein-learned-to-switch-sides/
BSN: 2010 Cold Spring Harbor Laboratory Meetings - Axon Guidance, Synaptic Plasticity and Regeneration
Speakers -------- N/A 2010 Cold Spring Harbor Laboratory Meetings Meetings Axon Guidance, Synaptic Plasticity and Regeneration September 21 - 25 abs due July 2 Cold Spring Harbor Laboratory Meetings Program, 1 Bungtown Road, Cold Spring Harbor, NY 11724 Phone 516 367 8346 email [email protected] http://www.cshl.edu/meetings ...
http://www.biotechsciencenews.com/Event/1751.html
Cold Spring Harbor symposia on quantitative biology | 佐賀大学OPACCold Spring Harbor symposia on quantitative biology | 佐賀大学OPAC
Cold Spring Harbor Symposium on Quantitative Biology, Cold Spring Harbor Laboratory of Quantitative Biology. Cold Spring Harbor Laboratory, University of Tokyo Press. ...
http://opac.lib.saga-u.ac.jp/opc/recordID/catalog.bib/BA00289506
Postdoctoral Fellow in Neuroscience at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York 11724 | Cell Career NetworkPostdoctoral Fellow in Neuroscience at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York 11724 | Cell Career Network
Cold Spring Harbor Laboratory - Postdoctoral Fellow in Neuroscience - Cold Spring Harbor - A postdoctoral fellow position is available in the - Cell Career Network
http://jobs.cell.com/jobs/postdoctoral-fellow-in-neuroscience-cold-spring-harbor-new-york-11724-102906228-d?contextType=browseSpotlight
Exhibit Tags: oncogenes / Format: Text / Genre: Articles / Periodical: Cancer Surveys / Publisher: Cold Spring Harbor...Exhibit Tags: oncogenes / Format: Text / Genre: Articles / Periodical: Cancer Surveys / Publisher: Cold Spring Harbor...
You searched for: Exhibit Tags oncogenes Remove constraint Exhibit Tags: oncogenes Format Text Remove constraint Format: Text Genre Articles Remove constraint Genre: Articles Periodical Cancer Surveys Remove constraint Periodical: Cancer Surveys Publisher Cold Spring Harbor Laboratory. Press Remove constraint Publisher: Cold Spring Harbor Laboratory. Press Subject Mutagenesis Remove constraint Subject: Mutagenesis ...
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Cold Spring Harbor Protocols highlights reliable methods for gene and protei...( COLD SPRING HARBOR N.Y. (Wed. Apr. ...)
... COLD SPRING HARBOR N.Y. (Wed. Apr. 4 2007) In their native ...One of the freely available methods (A HREF http://www.cshprotocols....To test the activity of a certain gene during embryonic development m...,Cold,Spring,Harbor,Protocols,highlights,reliable,methods,for,gene,and,protein,analyses,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
http://news.bio-medicine.org/biology-news-3/Cold-Spring-Harbor-Protocols-highlights-reliable-methods-for-gene-and-protein-analyses-2065-1/
Retroviruses 2004: Review of the 2004 Cold Spring Harbor Retroviruses conference | Retrovirology | Full TextRetroviruses 2004: Review of the 2004 Cold Spring Harbor Retroviruses conference | Retrovirology | Full Text
For the past several decades, retrovirologists from around the world have gathered in late May at the Cold Spring Harbor Laboratories in New York to present their studies in formal talks and posters, and to discuss their ongoing research informally at the bar or on the beach. As organizers of the 2004 Cold Spring Harbor Retroviruses Conference, we have been asked by the editors of Retrovirology to prepare a review of the meeting for publication on-line. Our goal in this review is not to provide a detailed description of data presented at the meeting but rather to highlight some of the significant developments reported this year. The review is structured in a manner that parallels the organization of the meeting; beginning with the entry phase of the replication cycle, proceeding with post-entry events, assembly and release, integration, reverse transcription, pathogenesis/host factors, RNA-related events (transcription, processing, export, and packaging) and finishing with antivirals. While the most
https://retrovirology.biomedcentral.com/articles/10.1186/1742-4690-1-25
Creator: Watson, James D., 1928- / Format: Text / Language: English / Publisher: Cold Spring Harbor Laboratory. Press - Francis...Creator: Watson, James D., 1928- / Format: Text / Language: English / Publisher: Cold Spring Harbor Laboratory. Press - Francis...
You searched for: Creator Watson, James D., 1928- Remove constraint Creator: Watson, James D., 1928- Format Text Remove constraint Format: Text Language English Remove constraint Language: English Publisher Cold Spring Harbor Laboratory. Press Remove constraint Publisher: Cold Spring Harbor Laboratory. Press ...
https://profiles.nlm.nih.gov/spotlight/sc/catalog?f%5Breadonly_creator_ssim%5D%5B%5D=Watson%2C+James+D.%2C+1928-&f%5Breadonly_format_ssim%5D%5B%5D=Text&f%5Breadonly_language_ssim%5D%5B%5D=English&f%5Breadonly_publisher_ssim%5D%5B%5D=Cold+Spring+Harbor+Laboratory.+Press&per_page=50&search_field=all_fields&sort=readonly_title_ssim+asc&view=gallery
CSHL study unmasks a stem cell origin of skin cancer and the genetic roots of ... ( Cold Spring Harbor N.Y. A constella...)CSHL study unmasks a stem cell origin of skin cancer and the genetic roots of ... ( Cold Spring Harbor N.Y. A constella...)
Health, ...Cold Spring Harbor N.Y. A constellation of different stem cell popul...Researchers at Cold Spring Harbor Laboratory (CSHL) led by Associate P...When cells in the skin or anywhere else in the body sense a potentiall... Unfortunately there are a number of genetic events that can bypass se...,CSHL,study,unmasks,a,stem,cell,origin,of,skin,cancer,and,the,genetic,roots,of,malignancy,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
http://www.bio-medicine.org/medicine-news-1/CSHL-study-unmasks-a-stem-cell-origin-of-skin-cancer-and-the-genetic-roots-of-malignancy-78951-1/
Cold Spring Harbor Protocols features tissue culture methods for immune cells a... ( COLD SPRING HARBOR N.Y. (Tues. Dec....)Cold Spring Harbor Protocols features tissue culture methods for immune cells a... ( COLD SPRING HARBOR N.Y. (Tues. Dec....)
Health, ... COLD SPRING HARBOR N.Y. (Tues. Dec. 2 2008) The complexity ... Bone Marrow-Derived Macrophages (BMM): Isolation and Applications f...Primary cultures of granule neurons from the cerebellum provide an exc...,Cold,Spring,Harbor,Protocols,features,tissue,culture,methods,for,immune,cells,and,neurons,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
http://www.bio-medicine.org/medicine-news-1/Cold-Spring-Harbor-Protocols-features-tissue-culture-methods-for-immune-cells-and-neurons-31019-1/
Bipolar Disorder Therapists in Cold Spring Harbor, New York - TherapyTribeBipolar Disorder Therapists in Cold Spring Harbor, New York - TherapyTribe
Find bipolar disorder therapists, psychologists and bipolar disorder counselors in Cold Spring Harbor, New York. Search now for detailed listings and contact a bipolar disorder therapist in Cold Spring Harbor that fits your needs!
https://www.therapytribe.com/therapist/new-york-ny-cold-spring-harbor/bipolar-disorder/
WorkGroup Home - Clinical Genomics - ConfluenceWorkGroup Home - Clinical Genomics - Confluence
The Clinical Genomics Work Group supports the HL7 mission to create and promote its standards by enabling the semantically meaningful exchange of data between parties interested in clinical, personal, and population genomic information and family health history, which are required to support personalized / precision medicine. The focus of the clinical genomics domain is the identification of an individuals genomic data and family health history, to better understand the underlying genetic factors contributing to disease and health, and the linking to relevant clinical information including both data and knowledge. The long term vision of the Clinical Genomics Work Group includes within its scope omics technologies and data types related to genomics, including genetics, epigenetics, proteomics, etc.. This work group will facilitate the development of common standards for clinical and translational information management across a variety of organizations, including (but not limited to): 1) ...
https://confluence.hl7.org/display/CGW/WorkGroup+Home
Home - Genomics Data ScienceHome - Genomics Data Science
A genome is the DNA or genetic material of an organism and it contains all of the information needed to build that organism. Genomics is the study of the genomes and modern genomics technologies such as high-throughput DNA sequencing technologies generate vast amounts of genomics data. Genomics Data Science is an interdisciplinary field that applies statistics and the tools of data science to analyze and interpret the data generated by modern genomics technologies. Data generated by these technologies is often termed multi-omics data and can include information on DNA, RNA, proteins, epigenetic modifications and metabolites, amongst others. Genomics Data Science allows us to better understand biological systems, and to leverage genomic technologies to benefit science, medicine, society and the economy. ...
https://genomicsdatascience.ie/
Library Policies - Cold Spring Harbor Laboratory - Library & ArchivesLibrary Policies - Cold Spring Harbor Laboratory - Library & Archives
Cold Spring Harbor Laboratory - Founded in 1890, CSHL is a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, and bioinformatics and a broad educational mission.
https://library.cshl.edu/about-us/library-policies
internship icmr genomics centre 2018 - Noticebard
About: The ICMR Computational Genomics Centre (ICGC) provides opportunities for outstanding students to carry out project work under the supervision of the experienced scientists at the Centre. Students pursuing B.Sc/B.Tech. /MCA/M.Sc. /M.Tech/Ph.D. degree and working professionals are encouraged to apply. There are 16 internship positions available this year related to subject areas like bioinformatics, Genomics, Structure based Drug Design, Next Generation Sequencing, Big-Data analytics and Cloud Computing, Web & Database Development. Only selected students will be informed by 05th May. Selected students will … Read MoreInternship Opportunity @ ICMR Computational Genomics Centre [16 Interns]: Apply by Apr 30. ...
https://www.noticebard.com/tag/internship-icmr-genomics-centre-2018/
E-Books - Cold Spring Harbor Laboratory - Library & ArchivesE-Books - Cold Spring Harbor Laboratory - Library & Archives
Cold Spring Harbor Laboratory - Founded in 1890, CSHL is a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, and bioinformatics and a broad educational mission.
http://library.cshl.edu/resources/library-newsletter/153-2012-04-newsletter/266-e-books
CSHLPress.com - biological rhythms cellular physiology organismal behaviorCSHLPress.com - biological rhythms cellular physiology organismal behavior
COLD SPRING HARBOR, N.Y. (Sept. 4, 2008) - A variety of organisms-from bacteria and fungi to plants and animals-have biological rhythms, where the timing and duration of fundamental biological processes is naturally adjusted to allow them to adapt and survive, even under fluctuating environmental conditions. In recent years, significant advances have been made to understand the molecular basis of these rhythms and how they translate into modifications in cellular physiology and organismal behavior.. A new book from Cold Spring Harbor Laboratory Press, Clocks and Rhythms, reviews the latest advances in biological clocks and rhythms across a broad range of species and biological disciplines. Chapters in the book are based on presentations by world-renowned investigators at the 72nd annual Cold Spring Harbor Symposium on Quantitative Biology at Cold Spring Harbor Laboratory, which was attended by 316 scientists from more than 20 countries.. Since the discovery and cloning of the first clock gene, ...
https://cshlpress.com/press.tpl?pag=biological_rhythms_cellular_physiology_organismal_behavior
New book on malaria from Cold Spring Harbor Laboratory Press | EurekAlert! Science NewsNew book on malaria from Cold Spring Harbor Laboratory Press | EurekAlert! Science News
Written and edited by experts in the field, Malaria: Biology in the Era of Eradication, from Cold Spring Harbor Laboratory Press, explores recent developments in our understanding of malaria biology and their potential to influence malaria elimination/eradication strategies. The authors describe recent developments in their respective research areas and suggest both how these insights could guide intervention strategy and where critical knowledge gaps remain.
https://www.eurekalert.org/pub_releases/2017-02/cshl-nbo022117.php
Cold Spring Harbor Lab Press A <em>Cold Spring Harbor Perspectives in Biology</em...Cold Spring Harbor Lab Press A <em>Cold Spring Harbor Perspectives in Biology</em...
CSHL Press publishes monographs, technical manuals, handbooks, review volumes, conference proceedings, scholarly journals and videotapes. These examine important topics in molecular biology, genetics, development, virology, neurobiology, immunology and cancer biology. Manuscripts for books and for journal publication are invited from scientists world wide.
https://www.cshlpress.com/default.tpl?cart=15003154632195663&id1=126&startat=1&--woSECTIONSdatarq=126&--SECTIONSword=ww&--Rank_In_Seriessort=1&--Rank_In_Seriestype=number&--Rank_In_Seriessdir=as
Charity Navigator - Rating for Cold Spring Harbor LaboratoryCharity Navigator - Rating for Cold Spring Harbor Laboratory
Cold Spring Harbor Laboratory is rated 4 out of 4 stars by Charity Navigator. Cold Spring Harbor Laboratory receives 91.44 out of 100 for their Charity Navigator rating. Cold Spring Harbor Laboratory is a Non-Medical Science & Technology Research charity located in Cold Spring Harbor, NY. The organization is run by Bruce Stillman and has an annual revenue of $212,525,469.
https://www.charitynavigator.org/index.cfm?bay=search.summary&orgid=3529
A Rapid and Efficient Method for Purifying High Quality Total RNA from Peaches (Prunus persica) for Functional Genomics AnalysesA Rapid and Efficient Method for Purifying High Quality Total RNA from Peaches (Prunus persica) for Functional Genomics Analyses
MEISEL, LEE et al. A Rapid and Efficient Method for Purifying High Quality Total RNA from Peaches (Prunus persica) for Functional Genomics Analyses. Biol. Res. [online]. 2005, vol.38, n.1, pp.83-88. ISSN 0716-9760. http://dx.doi.org/10.4067/S0716-97602005000100010.. Prunus persica has been proposed as a genomic model for deciduous trees and the Rosaceae family. Optimized protocols for RNA isolation are necessary to further advance studies in this model species such that functional genomics analyses may be performed. Here we present an optimized protocol to rapidly and efficiently purify high quality total RNA from peach fruits (Prunus persica). Isolating high-quality RNA from fruit tissue is often difficult due to large quantities of polysaccharides and polyphenolic compounds that accumulate in this tissue and co-purify with the RNA. Here we demonstrate that a modified version of the method used to isolate RNA from pine trees and the woody plant Cinnamomun tenuipilum is ideal for isolating high ...
https://scielo.conicyt.cl/scielo.php?script=sci_abstract&pid=S0716-97602005000100010&lng=en&nrm=iso&tlng=en
Structural genomics target selection for the New York consortium on membrane protein structure<...Structural genomics target selection for the New York consortium on membrane protein structure<...
TY - JOUR. T1 - Structural genomics target selection for the New York consortium on membrane protein structure. AU - Punta, Marco. AU - Love, James. AU - Handelman, Samuel. AU - Hunt, John F.. AU - Shapiro, Lawrence. AU - Hendrickson, Wayne A.. AU - Rost, Burkhard. PY - 2009/12. Y1 - 2009/12. N2 - The New York Consortium on Membrane Protein Structure (NYCOMPS), a part of the Protein Structure Initiative (PSI) in the USA, has as its mission to establish a high-throughput pipeline for determination of novel integral membrane protein structures. Here we describe our current target selection protocol, which applies structural genomics approaches informed by the collective experience of our team of investigators. We first extract all annotated proteins from our reagent genomes, i.e. the 96 fully sequenced prokaryotic genomes from which we clone DNA. We filter this initial pool of sequences and obtain a list of valid targets. NYCOMPS defines valid targets as those that, among other features, have at ...
https://einstein.pure.elsevier.com/en/publications/structural-genomics-target-selection-for-the-new-york-consortium--2
Chemical genomics : reviews and protocols - University of Oklahoma Libraries
Introduction to chemical genomics / Paul R. Caron -- Chemistry for chemical genomics / Lutz Weber -- Computer-aided design of small molecules for chemical genomics / Philip M. Dean -- Design, synthesis, and screening of biomimetic ligands for affinity chromatography / Ana Cecília A. Roque, Geeta Gupta, and Christopher R. Lowe -- The role and application of in silico docking in chemical genomics research / Aldo Jongejan ... [et al.] -- Synthesis of complex carbohydrates and glyconjugates: enzymatic synthesis of globotetraose using #-1,3-N-acetylgalactosaminyltransferase LgtD from Haemophilus infuenzae strain Rd / Kang Ryu ... [et al.] -- High-throughput cloning for proteomics research / Sharon A. Doyle -- Screening for the expression of soluble recombinant protein in Escherichia coli / Sharon A. Doyle -- High-throughput purification of hexahistidine-tagged proteins expressed in Escherichia coli / Michael B. Murphy and Sharon A. Doyle -- The wheat germ cell-free expression system: methods for ...
http://link.libraries.ou.edu/portal/Chemical-genomics--reviews-and-protocols-edited/v-dNeX2aXdU/
Insights into the Dekkera bruxellensis genomic landscape: comparative genomics reveals variations in ploidy and nutrient...Insights into the Dekkera bruxellensis genomic landscape: comparative genomics reveals variations in ploidy and nutrient...
Insights into the Dekkera bruxellensis genomic landscape: comparative genomics reveals variations in ploidy and nutrient utilisation potential amongst wine isolates.
https://bee.oregonstate.edu/biblio/insights-dekkera-bruxellensis-genomic-landscape-comparative-genomics-reveals-variations
Comparative Genomics Uncovers Large Tandem Chromosomal Duplications in Mycobacterium bovis BCG PasteurComparative Genomics Uncovers Large Tandem Chromosomal Duplications in Mycobacterium bovis BCG Pasteur
International Journal of Genomics is a peer-reviewed, Open Access journal that publishes research articles as well as review articles in all areas of genome-scale analysis. Topics covered by the journal include, but are not limited to: bioinformatics, clinical genomics, disease genomics, epigenomics, evolutionary genomics, functional genomics, genome engineering, and synthetic genomics.
https://www.hindawi.com/journals/ijg/2000/217049/abs/
Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes...Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes...
1. Harries HM, Fletcher ST, Duggan CM. et al. The use of genomics technology to investigate gene expression changes in cultured human liver cells. Toxicol In Vitro. 2001 ;15:399-405 2. Hong Y, Muller UR, Lai F. Discriminating two classes of toxicants through expression analysis of HepG2 cells with DNA arrays. Toxicol In Vitro. 2003 ;17:85-92 3. Deaciuc IV, Arteel GE, Peng X. et al. Gene expression in the liver of rats fed alcohol by means of intragastric infusion. Alcohol. 2004 ;33:17-30 4. Deaciuc IV, Doherty DE, Burikhanov R. et al. Large-scale gene profiling of the liver in a mouse model of chronic, intragastric ethanol infusion. J Hepatol. 2004 ;40:219-27 5. Seth D, Leo MA, McGuinness PH. et al. Gene expression profiling of alcoholic liver disease in the baboon (Papio hamadryas) and human liver. Am J Pathol. 2003 ;163:2303-17 6. Brown PO, Botstein D. Exploring the new world of the genome with DNA microarrays. Nat Genet. 1999 ;21:33-7 7. Khan J, Saal LH, Bittner ML. et al. Expression ...
http://www.medsci.org/v04p0028.htm
Microarrays for an integrative genomics - Boston University Libraries
div class=citation vocab=http://schema.org/,,i class=fa fa-external-link-square fa-fw,,/i, Data from ,span resource=http://link.bu.edu/portal/Microarrays-for-an-integrative-genomics-Isaac-S./xrKzhjarrvA/ typeof=Book http://bibfra.me/vocab/lite/Item,,span property=name http://bibfra.me/vocab/lite/label,,a href=http://link.bu.edu/portal/Microarrays-for-an-integrative-genomics-Isaac-S./xrKzhjarrvA/,Microarrays for an integrative genomics, Isaac S. Kohane, Alvin T. Kho, and Atul J. Butte,/a,,/span, - ,span property=potentialAction typeOf=OrganizeAction,,span property=agent typeof=LibrarySystem http://library.link/vocab/LibrarySystem resource=http://link.bu.edu/,,span property=name http://bibfra.me/vocab/lite/label,,a property=url href=http://link.bu.edu/,Boston University Libraries,/a,,/span,,/span,,/span,,/span,,/div ...
http://link.bu.edu/portal/Microarrays-for-an-integrative-genomics-Isaac-S./xrKzhjarrvA/
Plant Genomics Undergraduate InternshipsPlant Genomics Undergraduate Internships
Please pass this along to undergraduate students and their advisors Plant Genomics Internships at the University of Missouri-Columbia The University of Missouri-Columbia is offering undergraduate summer research internships in PLANT GENOMICS. Visit our website: http://www.LSUROP.missouri.edu/pgi Application form available at: http://www.LSUROP.missouri.edu/PDFs/nonMUapp.pdf Details - Eight-week summer program (June 8-August 2, 2003) - $3100 stipend, to cover educational and personal expenses - Room (double) and board provided on-campus in air-conditioned dormitories - Travel expenses to and from Columbia provided - Travel money available to present research at a scientific meeting Plant Genomics at Missouri The University of Missouri-Columbia (MU) is a nationally recognized center for plant genetics research and has recently been awarded multiple grants from the National Science Foundation to fund research in plant genomics. Faculty in Biological Sciences, Biochemistry, Plant Sciences, and ...
http://www.bio.net/bionet/mm/arab-gen/2003-February/009458.html
Download Comparative Genomics: Recomb 2006 International Workshop, Rcg 2006 Montreal, Canada, September 24-26, 2006 ProceedingsDownload Comparative Genomics: Recomb 2006 International Workshop, Rcg 2006 Montreal, Canada, September 24-26, 2006 Proceedings
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Genomics spurs rapid advances in our understanding of the biology of vascular wilt pathogens in the genus Verticillium<...
TY - JOUR. T1 - Genomics spurs rapid advances in our understanding of the biology of vascular wilt pathogens in the genus Verticillium. AU - Klimes, A.. AU - Dobinson, K.F.. AU - Thomma, B.. AU - Klosterman, S.J.. PY - 2015. Y1 - 2015. N2 - The availability of genomic sequences of several Verticillium species triggered an explosion of genome-scale investigations of mechanisms fundamental to the Verticillium life cycle and disease process. Comparative genomics studies have revealed evolutionary mechanisms, such as hybridization and interchromosomal rearrangements, that have shaped these genomes. Functional analyses of a diverse group of genes encoding virulence factors indicate that successful host xylem colonization relies on specific Verticillium responses to various stresses, including nutrient deficiency and host defense-derived oxidative stress. Regulatory pathways that control responses to changes in nutrient availability also appear to positively control resting structure development. ...
https://research.wur.nl/en/publications/genomics-spurs-rapid-advances-in-our-understanding-of-the-biology
Full-time staff bioinformatics position, University of Minnesota Genomics CenterFull-time staff bioinformatics position, University of Minnesota Genomics Center
We seek a bioinformatician with computational and analytical skills to join the University of Minnesota Genomics Center (UMGC). The UMGC provides a wide range of innovative genomic services to UMN and external researchers, with a particular focus on next-generation sequencing (NGS). The UMGC operates a fleet of advanced sequencing instruments, including Illumina HiSeq and MiSeq sequencers, a PacBio Sequel sequencer, the 10X Chromium system, and the Fluidigm C1 single-cell system. Through a partnership with the University of Minnesota Supercomputing Institute (MSI), the UMGCs informatics infrastructure is supported by MSIs HPC compute clusters, high-performance storage platforms, and cloud-computing infrastructure. This position in our Informatics group will support the Operations group in providing genomics services to customers, and work with the R&D group to push the limits of the UMGCs instrumentation and put into production the latest advances in sequencing technology.. Required (Minimum) ...
https://www.biostars.org/p/230952/
Cold Springs FCCLA brings home state awards - Cullman Times OnlineCold Springs FCCLA brings home state awards - Cullman Times Online
Cold Springs FCCLA students took home an array of honors at state conference, with one student advancing to compete nationally. On March 9-10, 2017, Cold Springs FCCLA students attended the FCCLA State Meeting in Montgomery. Members throughout Alabama gathered to increase their leadership skills, explore career options, compete in the state FCCLA STAR Events and elect a new team of state officers. With FCCLA there are unlimited opportunities for our youth. This year Cold Springs had a student, Matthew Blair, to run for the FCCLA Executive Council Officer position. Matthew ran for this office with 10 other young adults from all over Alabama. Only six are chosen for the Executive Council. Matthew gave his speech and answered an on stage question to over 800 members, advisors, and guests. Matthew was voted in by his peers. He will be required to represent the state of Alabama at state and national meetings. Cold Springs FCCLA had five students to complete the Power of One projects and be recognized ...
https://www.genetherapy.me/hypopituitarism/cold-springs-fccla-brings-home-state-awards-cullman-times-online.php
Project Beta Cell Genomics database | NCBO BioPortal
Description: Beta cell genomics database provides searches and tools to explore detailed information about genes, transcripts, gene interactions, genomic regions, and beta cell related functional genomics studies. Institution: University of Pennsylvania Contacts: Beta Cell Biology Consortium Home Page: http://genomics.betacell.org/gbco/ ...
http://umls.bioportal.bioontology.org/projects/BCGD
Li BiaoruLi Biaoru
Biaoru Li is a Associate Member in the Division of Haematology and Oncology, GA Cancer Centre and Faculty of Research Scientist, Dept. of Pediatrics, MCG, Augusta, GA. His clinical hematology and oncology focuses on clinical genomics analysis and diagnosis (including clinical bio-banking, primary-cell proliferation and differentiation, genomic analysis in DNA, mRNA and protein, quantitative network and machine-learning modeling). For over 15 years, he had used the system to work on stem cell differentiating into erythroid, lymphocyte, myeloid, fibroblast and to study behavior of cancer stem cells and cancer stem cell reverse differentiation into normal stem cell. In clinical genomics diagnosis for hematology and oncology he also worked for clinical genomic database and genomics analysis/diagnosis from NGS, microarray and GWAS/SNP for oncology/hematology from clinical specimens. In clinical genomics analysis,he had set up different platform and used different software to study clinical ...
https://www.ommegaonline.org/editor-details/1085
Download Plant Functional Genomics (Methods In Molecular Biology Vol 236)
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American Journal of Bioethics special issue on personal genomics | WIREDAmerican Journal of Bioethics special issue on personal genomics | WIRED
The latest issue of the American Journal of Bioethics is devoted to the interlocking worlds of social networking and personal genomics, headed by an editorial written by the founders and employees of personal genomics company 23andMe.
https://www.wired.com/2009/06/american-journal-of-bioethics-special-issue-on-personal-genomics/
Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism | BMC Genomics |...Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism | BMC Genomics |...
Clostridium difficile is an anaerobic, Gram-positive bacterium that can reside as a commensal within the intestinal microbiota of healthy individuals or cause life-threatening antibiotic-associated diarrhea in immunocompromised hosts. C. difficile can also form highly resistant spores that are excreted facilitating host-to-host transmission. The C. difficile spo0A gene encodes a highly conserved transcriptional regulator of sporulation that is required for relapsing disease and transmission in mice. Here we describe a genome-wide approach using a combined transcriptomic and proteomic analysis to identify Spo0A regulated genes. Our results validate Spo0A as a positive regulator of putative and novel sporulation genes as well as components of the mature spore proteome. We also show that Spo0A regulates a number of virulence-associated factors such as flagella and metabolic pathways including glucose fermentation leading to butyrate production. The C. difficile spo0A gene is a global transcriptional
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-15-160
RCSB PDB - 3BIJ: Crystal structure of protein GSU0716 from Geobacter sulfurreducens. Northeast Structural Genomics target GsR13RCSB PDB - 3BIJ: Crystal structure of protein GSU0716 from Geobacter sulfurreducens. Northeast Structural Genomics target GsR13
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
http://www.rcsb.org/structure/3bij
Presentations<span class=avia-menu-fx><span class=avia-arrow-wrap><span class=avia-arrow>...
67. Wu Y, Klimas A, DSouza S, Schaniel C, Girnun GC, Entcheva E, Lyon GJ. (March 2016) Modeling Ogden syndrome in a dish using iPSCs. CiRA/ISSCR International Symposium Pluripotency: from Basic Science to Therapeutic Application. Kyoto University. Kyoto. Japan. Poster presentation by Yiyang Wu.. 66. Lyon, GJ, (March 2016) A rare genetic Transcriptomopathy syndrome leading to insights into more common neurologic disorders. Poster Presentation, Systems Biology: Global Regulation of Gene Expression Meeting, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. (View PDF). 65. Fang H, Doerfel M, Huang Y, Lyon GJ, Schatz MC (February 2016) Scikit-ribo: Accurate A-site prediction and robust modeling of translation control from Riboseq & RNAseq data. Platform presentation by Han Fang, Advances in Genome Biology and Technology(AGBT) Meeting, Orlando, FL.. 64. Fang H, Doerfel M, Huang Y, Lyon GJ, Schatz MC. (October 2015) Scikit-ribo: Accurate A-site prediction and robust modeling of translation ...
http://lyonlab.labsites.cshl.edu/presentations/
Pharmacogenetics of Warfarin | Clinical Genomics: Practical Applications in Adult Patient Care | AccessMedicine | McGraw-Hill...Pharmacogenetics of Warfarin | Clinical Genomics: Practical Applications in Adult Patient Care | AccessMedicine | McGraw-Hill...
Scott SA, Desnick RJ. Scott S.A., Desnick R.J. Scott, Stuart A., and Robert J. Desnick.Pharmacogenetics of Warfarin. In: Murray MF, Babyatsky MW, Giovanni MA, Alkuraya FS, Stewart DR. Murray M.F., Babyatsky M.W., Giovanni M.A., Alkuraya F.S., Stewart D.R. Eds. Michael F. Murray, et al.eds. Clinical Genomics: Practical Applications in Adult Patient Care, 1e New York, NY: McGraw-Hill; 2014. http://accessmedicine.mhmedical.com/content.aspx?bookid=1094§ionid=61899360. Accessed October 16, 2017 ...
http://accessmedicine.mhmedical.com/content.aspx?bookid=1094§ionid=61899360
Hemolytic Uremic Syndrome | Clinical Genomics: Practical Applications in Adult Patient Care | AccessMedicine | McGraw-Hill...Hemolytic Uremic Syndrome | Clinical Genomics: Practical Applications in Adult Patient Care | AccessMedicine | McGraw-Hill...
Mescla F, Remuzzi G, Noris M. Mescla F, Remuzzi G, Noris M Mescla, Federica, et al.Hemolytic Uremic Syndrome. In: Murray MF, Babyatsky MW, Giovanni MA, Alkuraya FS, Stewart DR. Murray M.F., Babyatsky M.W., Giovanni M.A., Alkuraya F.S., Stewart D.R. Eds. Michael F. Murray, et al.eds. Clinical Genomics: Practical Applications in Adult Patient Care, 1e New York, NY: McGraw-Hill; 2014. http://accessmedicine.mhmedical.com/content.aspx?bookid=1094§ionid=61903427. Accessed December 12, 2017 ...
http://accessmedicine.mhmedical.com/content.aspx?bookid=1094§ionid=61903427
Chromosomes] APPLIED COMPUTATIONAL GENOMICS COURSEChromosomes] APPLIED COMPUTATIONAL GENOMICS COURSE
Genome Canada APPLIED COMPUTATIONAL GENOMICS COURSE September 8-14, 2006, University of Manitoba Winnipeg, Manitoba, Canada (International attendees welcome!) ------------------------------------------------------ Bioinformatics in the post-genomic era requires the analysis of large and diverse datasets using automated tools. While many Web-based tools are available to the lab researcher, the Web is awkward for tasks beyond single-sequence annotation. Researchers need to become productive in a server-based Unix environment with its wealth of scripting and automation tools. Even at an entry-level, this can be an intimidating endeavor. The Genome Canada Bioinformatics Platform is empowering researchers by teaching a hands-on course, with lectures and tutorials presented by a panel of experts. The course uses tools and services available through the Genome Canada Bioinformatics Platform. Most tools used are open-source, and can be freely downloaded for use at ones home institution. Topics include ...
http://www.bio.net/bionet/mm/biochrom/2006-May/002710.html
Veterinary Pest Genomics Center | Ag Data CommonsVeterinary Pest Genomics Center | Ag Data Commons
The Veterinary Pest Genomics Center (VPGC) is an initiative within the US Department of Agricultures Agricultural Research Service (ARS). The vision for this initiative is to leverage big data solutions to evaluate risk from, and develop mitigations for invasive and other economically important veterinary pests. The introduction of invasive veterinary pests is accelerated by global change, including anomalies related to climate variability. An important aspect of this effort is to foster an innovation ecosystem involving the network of laboratories directly linked to ARS National Program 104 (Veterinary, Medical, and Urban Entomology), and related locations, in a way that allows ARS to leverage its scientific talent and other research assets.. VPGCs mission is to:. ...
https://data.nal.usda.gov/veterinary-pest-genomics-center/field_adc_hierarchy/animals-livestock-41/field_nal_author%3Afield_nal_author_name/wang%2C%20ju/field_tags/np104-3088/field_tags/new-world-screwworm-4319?sort_by=changed
Veterinary Pest Genomics Center | Ag Data CommonsVeterinary Pest Genomics Center | Ag Data Commons
The Veterinary Pest Genomics Center (VPGC) is an initiative within the US Department of Agricultures Agricultural Research Service (ARS). The vision for this initiative is to leverage big data solutions to evaluate risk from, and develop mitigations for invasive and other economically important veterinary pests. The introduction of invasive veterinary pests is accelerated by global change, including anomalies related to climate variability. An important aspect of this effort is to foster an innovation ecosystem involving the network of laboratories directly linked to ARS National Program 104 (Veterinary, Medical, and Urban Entomology), and related locations, in a way that allows ARS to leverage its scientific talent and other research assets.. VPGCs mission is to:. ...
https://data.nal.usda.gov/veterinary-pest-genomics-center/field_nal_author%3Afield_nal_author_name/temeyer%2C%20kevin%20b%252E/field_tags/r-microplus-1057
Genome Wide Analysis of Nucleotide-Binding Site Disease Resistance Genes in Brachypodium distachyonGenome Wide Analysis of Nucleotide-Binding Site Disease Resistance Genes in Brachypodium distachyon
International Journal of Genomics is a peer-reviewed, Open Access journal that publishes research articles as well as review articles in all areas of genome-scale analysis. Topics covered by the journal include, but are not limited to: bioinformatics, clinical genomics, disease genomics, epigenomics, evolutionary genomics, functional genomics, genome engineering, and synthetic genomics.
https://www.hindawi.com/journals/ijg/2012/418208/
Classical conditioning and sensitization share aspects of the same molecular cascade in Aplysia.<...
TY - JOUR. T1 - Classical conditioning and sensitization share aspects of the same molecular cascade in Aplysia.. AU - Kandel, E. R.. AU - Abrams, T.. AU - Bernier, L.. AU - Carew, Thomas. AU - Hawkins, R. D.. AU - Schwartz, J. H.. PY - 1983. Y1 - 1983. UR - http://www.scopus.com/inward/record.url?scp=0021009080&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0021009080&partnerID=8YFLogxK. M3 - Article. C2 - 6327178. AN - SCOPUS:0021009080. VL - 48 Pt 2. SP - 821. EP - 830. JO - Cold Spring Harbor Symposia on Quantitative Biology. JF - Cold Spring Harbor Symposia on Quantitative Biology. SN - 0091-7451. ER - ...
https://nyu-staging.pure.elsevier.com/en/publications/classical-conditioning-and-sensitization-share-aspects-of-the-sam
The erythropoietin receptor: Dimerization, activation, and tumorigenesis<...
TY - JOUR. T1 - The erythropoietin receptor. T2 - Dimerization, activation, and tumorigenesis. AU - Lodish, H. F.. AU - Hilton, D.. AU - Longmore, G.. AU - Watowich, S. S.. AU - Yoshimura, A.. PY - 1992. Y1 - 1992. UR - http://www.scopus.com/inward/record.url?scp=0026989099&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0026989099&partnerID=8YFLogxK. U2 - 10.1101/SQB.1992.057.01.013. DO - 10.1101/SQB.1992.057.01.013. M3 - Article. C2 - 1339709. AN - SCOPUS:0026989099. VL - 57. SP - 95. EP - 106. JO - Cold Spring Harbor Symposia on Quantitative Biology. JF - Cold Spring Harbor Symposia on Quantitative Biology. SN - 0091-7451. ER - ...
https://keio.pure.elsevier.com/en/publications/the-erythropoietin-receptor-dimerization-activation-and-tumorigen
Lymphocyte homing receptors<...
TY - JOUR. T1 - Lymphocyte homing receptors. AU - Hu, M. C T. AU - Siegelman, M. H.. AU - Holzmann, B.. AU - Crowe, D. T.. AU - Weissman, I. L.. PY - 1992/1/1. Y1 - 1992/1/1. UR - http://www.scopus.com/inward/record.url?scp=0026974462&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0026974462&partnerID=8YFLogxK. U2 - 10.1101/SQB.1992.057.01.034. DO - 10.1101/SQB.1992.057.01.034. M3 - Article. C2 - 1339666. AN - SCOPUS:0026974462. VL - 57. SP - 291. EP - 308. JO - Cold Spring Harbor Symposia on Quantitative Biology. JF - Cold Spring Harbor Symposia on Quantitative Biology. SN - 0091-7451. ER - ...
https://utsouthwestern.pure.elsevier.com/en/publications/lymphocyte-homing-receptors-2
Privacy Policy - Scarab GenomicsPrivacy Policy - Scarab Genomics
Scarab Genomics may share your information with others for the following reasons:. Your authorization: Scarab Genomics may share your personally identifiable information if you authorize Scarab Genomics to do so.. Agents of Scarab Genomics: Scarab Genomics may share your personally identifiable information, order-related information, training requests and correspondence with customer service with third parties who help Scarab Genomics deliver products or services, such as a shipping company. Those third parties include contractors, temporary employees and consultants and other companies working with Scarab Genomics (collectively, Agents). Agents are instructed to use your information to help Scarab Genomics deliver products or services.. Companies of Scarab Genomics: Scarab Genomics may share your personally identifiable information, technically related information, product notification requests, order-related information, training requests, software patch requests and correspondence with ...
http://www.scarabgenomics.com/privacy-policy/
Regulatory Network Identification by Genetical Genomics: Signaling Downstream of the Arabidopsis Receptor-Like Kinase ERECTA<...
TY - JOUR. T1 - Regulatory Network Identification by Genetical Genomics: Signaling Downstream of the Arabidopsis Receptor-Like Kinase ERECTA. AU - Terpstra, I.R.. AU - Snoek, L.B.. AU - Keurentjes, J.J.B.. AU - Peeters, A.J.M.. AU - van den Ackerveken, G.. PY - 2010. Y1 - 2010. N2 - Gene expression differences between individuals within a species can be largely explained by differences in genetic background. The effect of genetic variants (alleles) of genes on expression can be studied in a multifactorial way by application of genetical genomics or expression quantitative trait locus (eQTL) mapping. In this paper we present a strategy to construct regulatory networks by application of genetical genomics in combination with transcript profiling of mutants that are disrupted in single genes. We describe the network identification downstream of the receptor-like kinase ERECTA in Arabidopsis (Arabidopsis thaliana). Extending genetical genomics on the Landsberg erecta/Cape Verde islands (Ler/Cvi) ...
https://research.wur.nl/en/publications/regulatory-network-identification-by-genetical-genomics-signaling
Zinc in the structure of X-Ray Structure of Guanine Deaminase From Bacillus Subtilis Northeast Structural Genomics Consortium...
Mono- and Stereopictres of 5.0 Angstrom coordination sphere of Zinc atom in PDB 1tiy: X-Ray Structure of Guanine Deaminase From Bacillus Subtilis Northeast Structural Genomics Consortium Target SR160
http://zinc.atomistry.com/pdb1tiy.html
National Chemical Genomics Center | The Addi and Cassi Fund - Niemann Pick Type CNational Chemical Genomics Center | The Addi and Cassi Fund - Niemann Pick Type C
We have returned from the National Chemical Genomics Center (NCGC) and are busy working on pushing forward new therapy ideas for Addi and Cassi and Niemann Pick Type C disease using state-of-the-art cheminformatics methods. The robotic equipment the NCGC has established for testing cells and profiling compounds for large collections of chemicals is incredible. The [...]. ...
http://addiandcassi.com/tag/national-chemical-genomics-center/
From roundworms and prairie grasses: Universitys Ecological Genomics Institute...From roundworms and prairie grasses: Universitys Ecological Genomics Institute...
By Communications and Marketing. How does one start a totally new field of science? Just ask Kansas State Universitys Loretta Johnson, associate professor, and Michael Herman, professor, both in the Division of Biology.. Ten years ago, Johnson and Herman teamed up to start research in the new area of ecological genomics. To celebrate launching this new field of science, the Kansas State University Ecological Genomics Institute is hosting a special 10th anniversary symposium from Oct. 26-28 at the Kansas City Marriott on the Plaza.. The development of ecological genomics came from seemingly unrelated research programs. Hermans research had focused on the genetics of development in a roundworm called Caenorhabditis elegans, and Johnsons research had centered on the ecology and root systems of prairie grasses.. We both saw that by collaborating and learning from one another we could forge a new area to learn how ecological interactions are dictated by organisms genomes, or the collection of ...
http://www.k-state.edu/today/announcement.php?id=5517
2017 Release: NIH to expand critical catalog for genomics research - National Human Genome Research Institute (NHGRI)2017 Release: NIH to expand critical catalog for genomics research - National Human Genome Research Institute (NHGRI)
The National Institutes of Health (NIH) plans to expand its Encyclopedia of DNA Elements (ENCODE) Project, which is generating a fundamental genomics resource used by many scientists to study human health and disease. Funded by the National Human Genome Research Institute (NHGRI), part of NIH, the ENCODE Project strives to catalog all the genes and regulatory elements - the parts of the genome that control whether genes are active or not - in humans and select model organisms. With four years of additional support, NHGRI builds on a long-standing commitment to developing freely available genomics resources for use by the scientific community.
https://www.genome.gov/27567592/
Molecular basis of pathogenesis of coronaviruses: A comparative genomics approach to planetary health to prevent zoonotic...Molecular basis of pathogenesis of coronaviruses: A comparative genomics approach to planetary health to prevent zoonotic...
In the first quarter of the 21st century, we are already facing the third emergence of a coronavirus outbreak, thesevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the coronavirus disease 2019(COVID-19) pandemic. Comparative genomics can inform a deeper understanding of the pathogenesis ofCOVID-19. Previous strains of coronavirus, SARS-CoV, and Middle-East respiratory syndrome-coronavirus(MERS-CoV), have been known to cause acute lung injuries in humans. SARS-CoV-2 shares genetic similaritywith SARS-CoV with some modification in the S protein leading to their enhanced binding affinity toward theangiotensin-converting enzyme 2 (ACE2) receptors of human lung cells. This expert review examines thefeatures of all three coronaviruses through a conceptual lens of comparative genomics. In particular, the lifecycle of SARS-CoV-2 that enables its survival within the host is highlighted. Susceptibility of humans tocoronavirus outbreaks in the 21st century calls for comparisons ...
https://eprints.utas.edu.au/35332/
PLOS ONE: Functional Associations by Response Overlap (FARO), a Functional Genomics Approach Matching Gene Expression PhenotypesPLOS ONE: Functional Associations by Response Overlap (FARO), a Functional Genomics Approach Matching Gene Expression Phenotypes
The systematic comparison of transcriptional responses of organisms is a powerful tool in functional genomics. For example, mutants may be characterized by comparing their transcript profiles to those obtained in other experiments querying the effects on gene expression of many experimental factors including treatments, mutations and pathogen infections. Similarly, drugs may be discovered by the relationship between the transcript profiles effectuated or impacted by a candidate drug and by the target disease. The integration of such data enables systems biology to predict the interplay between experimental factors affecting a biological system. Unfortunately, direct comparisons of gene expression profiles obtained in independent, publicly available microarray experiments are typically compromised by substantial, experiment-specific biases. Here we suggest a novel yet conceptually simple approach for deriving Functional Association(s) by Response Overlap (FARO) between microarray gene expression
http://journals.plos.org/plosone/article/comments?id=10.1371/journal.pone.0000676
Nucleome Unveils South Asias Largest and Most Advanced Genomics Research Centre; To Sequence 5000 COVID Genomes - Apeksha...Nucleome Unveils South Asias Largest and Most Advanced Genomics Research Centre; To Sequence 5000 COVID Genomes - Apeksha...
Hyderabad: In a move that will mark the beginning of a new era in Indias genomics capability, Nucleome Informatics today unveiled South Asias largest and most advanced genomics facility, NKC Centre for Genomics Research in Hyderabad. The laboratory will carry out the latest third-generation sequencing and play a critical role in fighting the pandemic by sequencing 5000 COVID genomes and 500 human genomes. The laboratory, established in the memory of the late 6-time Member of the Parliament from Khandwa, Shri Nand Kumar Singh Chauhan, will also play a role in upping Indias potential in agriculture, animal husbandry, and personalised / precision medicine, among others.. Honble Minister of Defence, Shri Rajnath Singh along with Honble Chief Minister of Madhya Pradesh, Shri Shivraj Chauhan today inaugurated the state-of-the-art laboratory at a formal ceremony held at Le Meridien in the presence of Shri Dushyant Singh Baghel, MD and CEO, Nucleome Informatics. Honble Principal Scientific Adviser ...
https://apekshasandesh.com/nucleome-unveils-south-asias-largest-and-most-advanced-genomics-research-centre-to-sequence-5000-covid-genomes-58422
eMERGE & CSER: The Convergence of Genomics and Medicine - National Human Genome Research Institute (NHGRI)eMERGE & CSER: The Convergence of Genomics and Medicine - National Human Genome Research Institute (NHGRI)
Bethesda, Maryland 20814. On February 2, 2017, the National Human Genome Research Institute (NHGRI) sponsored the meeting eMERGE & CSER: The Convergence of Genomics and Medicine at the Bethesda Hyatt in Bethesda, Maryland.. The meeting focused on research that seeks to rapidly advance the knowledge necessary to develop best practices for the implementation of genomic sequence data into clinical care, as well as research that combines biorepositories with electronic medical record (EMR) systems for genomic discovery and genomic medicine implementation research.. ...
https://www.genome.gov/27567557/emerge--cser-the-convergence-of-genomics-and-medicine/
Targeting Key Vulnerabilities in Pancreatic Cancer | The New York Academy of SciencesTargeting Key Vulnerabilities in Pancreatic Cancer | The New York Academy of Sciences
Keynote Speakers: Neesha Dhani (Princess Margaret Hospital, Toronto), Steven D. Leach (Memorial Sloan Kettering Cancer Center) Speakers: Gregory Beatty (University of Pennsylvania Perelman School of Medicine), Neesha C. Dhani (Division of Medical Oncology & Hematology, University Health Network, Princess Margaret Cancer Centre/Ontario Cancer Institute), Mikala Egeblad (Cold Spring Harbor Laboratory), Douglas T. Fearon (Weill Cornell Medical College and Cold Spring Harbor Laboratory), Elda Grabocka (Department of Biochemistry and Molecular Pharmacology, NYU Langone School of Medicine), Costas A. Lyssiotis (Weill Cornell Medical College ), George Miller (NYU Langone Medical Center), Michael Ports (Gilead Sciences), Curtis B. Thompson (Halozyme Therapeutics, Inc)Pancreatic cancer patients currently have limited therapeutic options. This symposium explores breakthroughs in the pathogenesis and progression of pancreatic cancer, and efforts to exploit key vulnerabilities for novel therapeutic interventions.
https://www.nyas.org/events/2014/targeting-key-vulnerabilities-in-pancreatic-cancer/
NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY - Patent applicationNOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY - Patent application
0009]Patent document 1: International Publication No. WO2001/005801. [0010]Patent document 2: International Publication No. WO2005/026187. [0011]Patent document 3: Specification of Published U.S. Patent Application No. US2007/0105099. [0012]Patent document 4: International Publication No. WO2007/066737 [0013]Non-patent document 1: Benner, S. A., Burgstaller, P., Battersby, T. R. & Jurczyk, S. in The RNA World (eds Gesteland, R. F., Cech, T. R. & Atkins, J. F.) 163-181 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 1999). [0014]Non-patent document 2: Henry, A. A. & Romesberg, F. E. Beyond A, C, G and T: augmenting natures alphabet. Curr. Opin. Chem. Biol. 7, 727-733 (2003). [0015]Non-patent document 3: Moser, M. J. & Prudent, J. R. Enzymatic repair of an expanded genetic information system. Nucleic Acids Res. 31, 5048-5053 (2003). [0016]Non-patent document 4: Bergstrom, D. E. Orthogonal base pairs continue to evolve. Chem. Biol. 11, 18-20 (2004). [0017]Non-patent document 5: ...
http://www.patentsencyclopedia.com/app/20110053782
Protein Kinase C Inhibitor and Irradiation-induced Apoptosis: Relevance of the Cytochrome c-mediated Caspase-9 Death Pathway --...
2 Department of Radiation Oncology, University Hospital Zurich, CH-8091 Zurich, Switzerland [S. R., C. G., S. B., M. P.]; Laboratory for Biochemistry, Federal Institute of Technology, 8091 Zurich, Switzerland [S. R., K. W.]; Novartis Pharma Inc., 4002 Basel, Switzerland [D. F.]; and Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724 [M. S. S., S. W. L.] Abstract. Caspases are a family of cysteine proteases that constitute the apoptotic cell death machinery. We report the importance of the cytochrome c-mediated caspase-9 death pathway for radiosensitization by the protein kinase C (PKC) inhibitors staurosporine (STP) and PKC-412. In our genetically defined tumor cells, treatment with low doses of STP or the conventional PKC-specific inhibitor PKC-412 in combination with irradiation (5 Gy) potently reduced viability, enhanced mitochondrial cytochrome c release into the cytosol, and specifically stimulated the initiator caspase-9. Whereas treatment with each agent alone had a minimal ...
http://cgd.aacrjournals.org/cgi/content/abstract/11/9/491
Cold Spring/St. Joseph/Paynesville Veterinary Clinic - Veterinarian in Cold Spring, MN USCold Spring/St. Joseph/Paynesville Veterinary Clinic - Veterinarian in Cold Spring, MN US
Cold Spring/St. Joseph/Paynesville Veterinary Clinic is your local Veterinarian in Cold Spring serving all of your needs. Call us today at 320-363-7756 for an appointment.
https://www.cssjpvets.com/articles/general/page/22
Cold Spring/St. Joseph/Paynesville Veterinary Clinic - Veterinarian in Cold Spring, MN USCold Spring/St. Joseph/Paynesville Veterinary Clinic - Veterinarian in Cold Spring, MN US
Cold Spring/St. Joseph/Paynesville Veterinary Clinic is your local Veterinarian in Cold Spring serving all of your needs. Call us today at 320-363-7756 for an appointment.
https://www.cssjpvets.com/articles/general/593750-medication-tips-for-your-pet
Public health genomics - WikipediaPublic health genomics - Wikipedia
Public health genomics is the use of genomics information to benefit public health. This is visualized as more effective personalized preventive care and disease treatments with better specificity, targeted to the genetic makeup of each patient. According to the CDC, Public Health genomics is an emerging field of study that assesses the impact of genes and their interaction with behavior, diet and the environment on the populations health. This field of public health genomics is less than a decade old. A number of think tanks, universities, and governments (including the U.S., UK, and Australia) have started public health genomics projects. Research on the human genome is generating new knowledge that is changing public health programs and policies. Advances in genomic sciences are increasingly being used to improve health, prevent disease, educate and train the public health workforce, other healthcare providers, and citizens. Public policy has protected people against genetic discrimination, ...
https://en.wikipedia.org/wiki/Public_health_genomics
Symposium on Genomics in Clinical Practice: Future of Precision Medicine | June 1-2, 2016 ~ helpBIOTECH
Symposium on Genomics in clinical practice: Future of precision medicine. Date: June 1-2, 2016. Venue: Yenepoya University, Mangalore. About the workshop:. YU-IOB Center for Systems Biology and Molecular Medicine and Yenepoya Research Center are organizing a Symposium on Genomics in clinical practice: Future of precision medicine. YU-IOB Center for Systems Biology and Molecular Medicine (YU-IOB CSBMM) is a premier center for research in the cutting-edge areas of Proteomics, Genomics and Bioinformatics formed as a result of a collaborative effort between Yenepoya University and Institute of Bioinformatics, Bangalore. We are organizing this symposium with an aim to educate clinicians, researchers and students about advances in clinical genomics and how it is paving the way for precision medicine. We are inviting experts from various organizations for this event. Our goal is to bring together practitioners of the field to give talks that can educate the participants on current advances and a ...
http://www.helpbiotech.co.in/2016/05/symposium-on-genomics-in-clinical.html
Genomics Network (archive) | Genomics Forum
Established in August 2004, the ESRC Genomics Policy and Research Forum was a novel initiative in the field of social science research. As part of the ESRC Genomics Network, the Forum acted to integrate the diverse strands of social science research within and beyond the Network; to develop links between social scientists and scientists working across the entire range of genomic science and technology; and to connect research in this area to policy makers, business, the media and civil society in the UK and abroad.. A key part of the Forums work was to exploit synergies across the ESRC Genomics Network, and to ensure the visibility and use of the Network and its output. These functions were no longer needed when the Network ceased operations and so the Forum closed in June 2013.. This archive website preserves the output of the Genomics Forum, including details of its research and publications.. ...
http://www.genomicsnetwork.ac.uk/forum/
ASMscience | Comparative Genomics ofASMscience | Comparative Genomics of
The use of comparative genomics combined with robust methods for data analysis will continue and will form the basis for the development of rational intervention strategies to reduce Campylobacter jejuni in the food chain. This chapter reviews the salient comparative features of the four fully sequenced genomes and reveals highlights from selected whole-genome microarray studies. The publication of the first C. jejuni genome paved the way for comparative genomics of this species. The relative genome diversity of bacterial species varies from clonal (genetically uniform) to genetically highly variable. The majority of genes on CJIE3 are of unknown function, although 23% share homology with Helicobacter hepaticus ATCC 51449 genomic island (HHGI1). Recent comparative phylogenomics studies have been undertaken on increasingly large collections of strains from defined origins. The chapter discusses case studies of C. jejuni genomic comparisons by microarray. More recently, the authors studied over 230 C.
https://www.asmscience.org/content/book/10.1128/9781555815554.ch04
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogrammingFunctional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) by expression of defined embryonic factors. However, little is known of the molecular mechanisms underlying the reprogramming process. Here we explore somatic cell reprogramming by exploiting a secondary mouse embryonic fibr …
https://pubmed.ncbi.nlm.nih.gov/20621051/?dopt=Abstract
UCSC Genome Browser: PublicationsUCSC Genome Browser: Publications
de Leeuw N, Dijkhuizen T, Hehir-Kwa JY, Carter NP, Feuk L, Firth HV, Kuhn RM, Ledbetter DH, Martin CL, van Ravenswaaij-Arts CM, Scherer SW, Shams S, Van Vooren S, Sijmons R, Swertz M, Hastings R. Diagnostic interpretation of array data using public databases and internet sources. Hum Mutat. 2012 Jun;33(6):930-40. PMID: 26285306; PMC: PMC5027376 Dreszer TR, Karolchik D, Zweig AS, Hinrichs AS, Raney BJ, Kuhn RM, Meyer LR, Wong M, Sloan CA, Rosenbloom KR, Roe G, Rhead B, Pohl A, Malladi VS, Li CH, Learned K, Kirkup V, Hsu F, Harte RA, Guruvadoo L, Goldman M, Giardine BM, Fujita PA, Diekhans M, Cline MS, Clawson H, Barber GP, Haussler D, Kent WJ The UCSC Genome Browser database: extensions and updates 2011. Nucleic Acids Res. 2012 Jan;40(Database issue):D918-23. PMID: 22086951; PMC: PMC3245018. ENCODE Project Consortium, Dunham I, Kundaje A, Aldred SF, Collins PJ, Davis CA, Doyle F, Epstein CB, Frietze S, Harrow J et al. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012 ...
http://ucscbrowser.genap.ca/goldenPath/pubs.html
ASMscience | Comparative Genomics ofASMscience | Comparative Genomics of
This chapter describes the approaches and results of comparative genomic analysis of Deinococcaceae with an emphasis on stress response systems and their impact on contemporary models of extreme ionizing radiation (IR) resistance. Clusters of orthologous genes (COGs) are the most useful framework for comparative genomics. Researchers assigned the proteins of D. deserti to tdCOGs, which has reinforced the view of the proliferation of Deinococcaceae genes involved in stress response pathways. Gene expression in D. radiodurans recovering from high-dose irradiation has been investigated using whole genome microarrays, which identified hundreds of D. radiodurans genes that were upregulated during recovery. The radiation/desiccation response (RDR) regulon is dominated by DNA repair genes, including the recombinational repair proteins RecA and RecQ, the mismatch repair proteins MutS and MutL, and the UvrB and UvrC proteins, which are involved in nucleotide excision repair. The prospect of comparative genomics
http://www.asmscience.org/content/book/10.1128/9781555816841.ch27
Plant Proteogenomics: Improvements to the Grapevine Genome Annotation - Murdoch Research RepositoryPlant Proteogenomics: Improvements to the Grapevine Genome Annotation - Murdoch Research Repository
Grapevine is an important perennial fruit to the wine industry, and has implications for the health industry with some causative agents proven to reduce heart disease. Since the sequencing and assembly of grapevine cultivar Pinot Noir, several studies have contributed to its genome annotation. This new study further contributes toward genome annotation efforts by conducting a proteogenomics analysis using the latest genome annotation from CRIBI, legacy proteomics dataset from cultivar Cabernet Sauvignon and a large RNA-seq dataset. A total of 341 novel annotation events are identified consisting of five frame-shifts, 37 translated UTRs, 15 exon boundaries, one novel splice, nine novel exons, 159 gene boundaries, 112 reverse strands, and one novel gene event in 213 genes and 323 proteins. From this proteogenomics evidence, the Augustus gene prediction tool predicted 52 novel and revised genes (54 protein isoforms), 11 genes of which are associated with key traits such as stress tolerance and ...
http://researchrepository.murdoch.edu.au/id/eprint/38827/
Difference between revisions of Marcel Dinger - Profile - Marcel Dinger
Marcel Dinger is Professor and Head of School for Biotechnology and Biomolecular Sciences at UNSW Sydney. He has more than 20 years experience in genomics as both an academic and entrepreneur. He has published 150 papers that have collectively been cited ,22,000 times (Google Scholar h-index 56) and is (co)-founder of four startups in biotechnology and IT. He is a director on the board of Pryzm Health, a digital health enterprise focused on developed tools to enable precision healthcare at population-scale, a director on the governance board of the National Centre for Indigenous Genomics (NCIG), an ANU-based centre focused on using genomics to improve the health and well-being of Australias First Peoples, a director on the board of GenieUs, a genomics and machine-learning technology startup dedicated to finding new therapies for neurodegenerative diseases, and President of the Australasian Genomics Technologies Association (AGTA), the principal body for the promotion of genomics research and ...
https://marceldinger.net/index.php?title=Marcel_Dinger_-_Profile&diff=next&oldid=280
The evolution of DNA sequencing and cancer genomics based on next generation sequencing :: CCSU Theses & Dissertations
The first methods for sequencing DNA were developed in the mid-1970s (Strausberg et al. 2008). The sequencing efforts were labor-intensive, slow, and costly (Metzker, 2005). As a result, researchers could sequence only a few base pairs per year. By the time the human genome project began in 1990, only a few researchers were able to sequence 100,000 bases (Shendure et al. 2004). Sequencing of large numbers of samples required complex automations in order to obtain high throughput consistent quality (Metzker, 2005). Since then, improved sequencing technologies have allowed the field of genomics to evolve. Exciting new DNA sequencing technologies has lead to the sequencing of many microbial genomes and higher eukaryotes genomes (Metzker, 2005). These technological improvements have not only increased speed, but are also cost effective. Several platforms were discovered and are based on different principles that have differences in sequence read lengths and numbers (Marguerat et al. 2008). New ...
http://content.library.ccsu.edu/cdm/singleitem/collection/ccsutheses/id/1669/rec/17
Mammalian comparative genomics reveals genetic and epigenetic features associated with genome reshuffling in Rodentia | Grup de...Mammalian comparative genomics reveals genetic and epigenetic features associated with genome reshuffling in Rodentia | Grup de...
Understanding how mammalian genomes have been reshuffled through structural changes is fundamental to the dynamics of its composition, evolutionary relationships between species and, in the long run, speciation. In this work, we reveal the evolutionary genomic landscape in Rodentia, the most diverse and speciose mammalian order, by whole-genome comparisons of six rodent species and six representative outgroup mammalian species. The reconstruction of the evolutionary breakpoint regions across rodent phylogeny shows an increased rate of genome reshuffling that is approximately two orders of magnitude greater than in other mammalian species here considered. We identified novel lineage and clade-specific breakpoint regions within Rodentia and analyzed their gene content, recombination rates and their relationship with constitutive lamina genomic associated domains, DNase I hypersensitivity sites and chromatin modifications. We detected an accumulation of protein-coding genes in evolutionary ...
https://grupsderecerca.uab.cat/evolgenom/node/183
UW Medicine | Genomic Medicine at the University of WashingtonUW Medicine | Genomic Medicine at the University of Washington
These two grants laid the groundwork for investment from four additional awards. In October 2009, UW Medicine received a large-scale DNA sequencing project award from the National Heart, Lung, and Blood Institute (NHLBI), made under the auspices of the American Recovery and Reinvestment Act (ARRA) of 2009. The lions share, $25 million, has been used to launch the Northwest Genomics Center at UW Medicine. An additional $2 million grant from the states Life Sciences Discovery Fund is supporting the new centers infrastructure. Deborah A. Nickerson, professor of genome sciences and one of the centers principal investigators, says the grant recognizes UW Medicines expertise in genomics. Weve been working in the area of medical sequencing for quite some time, particularly in cardiovascular disease, says Nickerson.. The lions share, $25 million, has been used to launch the Northwest Genomics Center at UW Medicine. An additional $2 million grant from the states Life Sciences Discovery Fund is ...
http://depts.washington.edu/meddev/uwmedmagazine/archives/vol33-no1/genomic-medicine-at-the-university-of-washington.php
European Future Panel on Public Health Genomics | PACITAEuropean Future Panel on Public Health Genomics | PACITA
The emerging field of Public Health Genomics intends to integrate genome-based knowledge and technologies into public policy and into health services. It thus is expected that human genetics will develop from a specialist medical field pertaining mainly to those small groups of patients with a risk of developing an inherited (and mainly monogenetic) disease into a significant area of mainstream medicine. Predictive testing for susceptibilities to develop common diseases (such as diabetes mellitus and cancer) e.g. is regarded as a field for Public Health Genomics.. A discussion on Public Health Genomics (including fields and concepts such as genetic population screening, pharmacogenetics, nutrigenetics, personalized medicine) has started in many European countries. The expansion of the reach of human genetics is promoted by some human geneticists and public health authority representatives (e.g. the Public Health Genomics Foundation). Critics argue that a public, preventive programme making use ...
http://www.pacitaproject.eu/public-health-genomics/
Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas<...Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas<...
TY - JOUR. T1 - Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas. AU - Olsen, Lars Rønn. AU - Campos, Benito. AU - Winther, Ole. AU - Sgroi, Dennis C.. AU - Karger, Barry L.. AU - Brusic, Vladimir. PY - 2014/12/8. Y1 - 2014/12/8. N2 - Background: The majority of genetic biomarkers for human cancers are defined by statistical screening of high-throughput genomics data. While a large number of genetic biomarkers have been proposed for diagnostic and prognostic applications, only a small number have been applied in the clinic. Similarly, the use of proteomics methods for the discovery of cancer biomarkers is increasing. The emerging field of proteogenomics seeks to enrich the value of genomics and proteomics approaches by studying the intersection of genomics and proteomics data. This task is challenging due to the complex nature of transcriptional and translation regulatory mechanisms and the disparities between genomic and proteomic data from the same samples. In this ...
https://research.nu.edu.kz/en/publications/tumor-antigens-as-proteogenomic-biomarkers-in-invasive-ductal-car
The Pathway to Genomic Medicine | BioEd OnlineThe Pathway to Genomic Medicine | BioEd Online
Slide set: The Pathway to Genomic Medicine. Richard Gibbs, PhD, explains genomic medicine and its role in and relationship to genetic research, and outlines how cutting-edge technologies and the study of genetics in human and in different species is transforming our understanding and treatment of human disease. This slide set accompanies the presentation, The Pathway to Genomic Medicine.
http://bioedonline.org/slides/content-slides/molecular-genetics/the-pathway-to-genomic-medicine/?pageaction=displaySlideDetails&tk=55&dpg=6
The Pathway to Genomic Medicine | BioEd OnlineThe Pathway to Genomic Medicine | BioEd Online
Slide set: The Pathway to Genomic Medicine. Richard Gibbs, PhD, explains genomic medicine and its role in and relationship to genetic research, and outlines how cutting-edge technologies and the study of genetics in human and in different species is transforming our understanding and treatment of human disease. This slide set accompanies the presentation, The Pathway to Genomic Medicine.
http://bioedonline.org/slides/content-slides/molecular-genetics/the-pathway-to-genomic-medicine/
The naked geneticists | Gene Expression
Girl_hands_out_flyer_at_Loveparade_03][1]John Hawks, [Genomes unzipped, unzipped][2]:. > _What I wonder is, how much will personal genomics be like nude beaches? I mean, its been a long time since the first nude beaches, but most people dont take advantage of the opportunity. Clearly, theres variation in different countries! But most people neither feel compelled to see others data nor feel comfortable sharing their own._ > > _Well, they used the word unzipped, not me!_. Obviously John had his tongue-firmly-planted-in-cheek, but I have wondered about this. **How deep is the impact of personal genomics going to be for individuals?** If a person gets their genome sequenced and has a list of [odds ratios][3] in front of them are they going to bone up on the [statistical genetic subtleties of the face value][3]?. That is where [genetic counselors][4] come in. The necessity of interpretative experts highlights the difference between nude beaches and personal genomics: personal genomics has more ...
http://fiveplanets.com/2010/10/12/the-naked-geneticists-gene-expression/
Anopheles Mosquito Comparative Genomics - Business Ideas PlanAnopheles Mosquito Comparative Genomics - Business Ideas Plan
Download full project about Anopheles Mosquito Comparative Genomics . Your business software is ready for download . You can use it for your own company / Office / home without any cost. We provide free business software for our visitor. The software is develop by using different model such as waterfall life-cycle ,traditional ,classic etc Anopheles Mosquito Comparative Genomics is a large and time consuming project. So, Our aim is to help all business vendors by sharing our best. We want your help by joining our community. You will get your project as you desire ...
https://businessideasplan.blogspot.com/2016/11/anopheles-mosquito-comparative-genomics.html
Safe Visit - Historic Cold Spring VillageSafe Visit - Historic Cold Spring Village
WELCOME, EVERYONE!. THANK YOU FOR VISITING HISTORIC COLD SPRING VILLAGE. FOR YOUR SAFETY PLEASE READ AND FOLLOW THE GUIDELINES BELOW. Please understand due to Covid-19 restrictions that not all buildings on Village grounds will be accessible and entrance for the Village is only through Seashore Road gatehouse 735 Seashore Road.. Historic Cold Spring Village requires face masks to enter all museum buildings.. Participants may choose to be mask-free outdoors. Social distancing is to remain in effect at all times.. Please practice physical distancing (6 feet) and be mindful of other guests and Village staff.. Public restrooms are available behind the Ice Cream parlor building.. Ice Cream Parlor is CLOSED for the season but frozen prepackaged treats are available at the Country Store.. Rules and guidelines are tentative and subject to change without prior notice.. ...
https://hcsv.org/safe-visit/?s=
minet : A R/Bioconductor Package for Inferring Large Transcriptional Networks Using Mutual Information | BMC Bioinformatics |...minet : A R/Bioconductor Package for Inferring Large Transcriptional Networks Using Mutual Information | BMC Bioinformatics |...
This paper presents the R/Bioconductor package minet (version 1.1.6) which provides a set of functions to infer mutual information networks from a dataset. Once fed with a microarray dataset, the package returns a network where nodes denote genes, edges model statistical dependencies between genes and the weight of an edge quantifies the statistical evidence of a specific (e.g transcriptional) gene-to-gene interaction. Four different entropy estimators are made available in the package minet (empirical, Miller-Madow, Schurmann-Grassberger and shrink) as well as four different inference methods, namely relevance networks, ARACNE, CLR and MRNET. Also, the package integrates accuracy assessment tools, like F-scores, PR-curves and ROC-curves in order to compare the inferred network with a reference one. The package minet provides a series of tools for inferring transcriptional networks from microarray data. It is freely available from the Comprehensive R Archive Network (CRAN) as well as from the
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-9-461
International Conference on Cancer Genomics and Proteomics in November 2020 in SingaporeInternational Conference on Cancer Genomics and Proteomics in November 2020 in Singapore
Cancer Genomics and Proteomics scheduled on November 19-20, 2020 in November 2020 in Singapore is for the researchers, scientists, scholars, engineers, academic, scientific and university practitioners to present research activities that might want to attend events, meetings, seminars, congresses, workshops, summit, and symposiums.
https://waset.org/cancer-genomics-and-proteomics-conference-in-november-2020-in-singapore
Sequence - Evolution - Function: Computational Approaches in Comparative ... - Eugene Koonin, Michael Y. Galperin - Google...Sequence - Evolution - Function: Computational Approaches in Comparative ... - Eugene Koonin, Michael Y. Galperin - Google...
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Key topics covered in this textbook are: *the completed and ongoing genome sequencing projects, *databases that store and organize genomic data, with their unique advantages and pitfalls, *principles and methods of genome analysis and annotation, *ways to automate the searches and increase search sensitivity while minimizing the error rate, *the first lessons from the Human Genome Project, *the contribution of comparative genomics to the understanding of hereditary diseases and cancer, *fundamental and practical applications of comparative genomics, *the use of complete genomes for evolutionary analysis, *the application of
https://books.google.com.mx/books?id=T_68UeOTowoC&vq=alignment&dq=editions:OCLC615342558&lr=&source=gbs_navlinks_s
Sequence - Evolution - Function: Computational Approaches in Comparative ... - Eugene Koonin, Michael Y. Galperin - Google...Sequence - Evolution - Function: Computational Approaches in Comparative ... - Eugene Koonin, Michael Y. Galperin - Google...
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Key topics covered in this textbook are: *the completed and ongoing genome sequencing projects, *databases that store and organize genomic data, with their unique advantages and pitfalls, *principles and methods of genome analysis and annotation, *ways to automate the searches and increase search sensitivity while minimizing the error rate, *the first lessons from the Human Genome Project, *the contribution of comparative genomics to the understanding of hereditary diseases and cancer, *fundamental and practical applications of comparative genomics, *the use of complete genomes for evolutionary analysis, *the application of
https://books.google.com.mx/books?id=T_68UeOTowoC&vq=multiple&dq=editions:OCLC615342558&lr=&source=gbs_navlinks_s
Mass at Assumption (Grasshopper) Chapel - Cold Spring - The Visitor
Cold Spring • Bishop Donald Kettler and Father Robert Rolfes celebrate Thanksgiving Mass at Assumption (Grasshopper) Chapel Mass at 7:30 p.m. Knights of Columbus Council #5344 hosts public rosary at 7 p.m. to honor of the 100-year anniversary of the Blessed Virgin Marys request to the children of Fatima for prayer and penance. Bring a lawn chair. (Turn off Hwy. 23 onto 3rd Ave. SE, take left at corner onto Chapel St., immediately take right onto Pilgrimage Rd. and up to chapel nestled in trees.) In case of rain or cold weather, Mass will be celebrated at St. Boniface Church on Main St. in Cold Spring.. ...
http://stcloudvisitor.org/event/mass-assumption-grasshopper-chapel-cold-spring/
Functional Genomics Approach to Identifying Genes Required for Biofilm Development by Streptococcus mutans | Applied and...Functional Genomics Approach to Identifying Genes Required for Biofilm Development by Streptococcus mutans | Applied and...
FIG. 6. Biofilm formation of S. mutans UA159 and its derivatives in BM medium. Crystal violet-stained 24-h biofilms of brpA (wells A5 to A7), ccpA (wells B4 and B5), and luxSSm (well B3) mutants and their parental strain UA159 (wells A2 and A4 and well B1). Wells A1 and B2 are uninoculated BM medium as negative control. The graphs show quantitation of the biofilms formed after 6 h (left) and 24 h (right) by ccpA (ccpA), brpA (brpA), and luxSsm (luxS) mutants and the wild-type (WT) strains. See the text for more details. Data are representative of no fewer than three separate experiments. The error bars represent standard deviations. ...
https://aem.asm.org/content/68/3/1196/figures-only
RCSB PDB - 2KKL: Solution NMR structure of FHA domain of Mb1858 from Mycobacterium bovis. Northeast Structural Genomics...RCSB PDB - 2KKL: Solution NMR structure of FHA domain of Mb1858 from Mycobacterium bovis. Northeast Structural Genomics...
2KKL: Solution NMR structure of FHA domain of Mb1858 from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR243C (24-155).
https://www.rcsb.org/3d-view/2KKL/0
GenomicsGenomics
A BMC journal on Genomics Genomics journal Genomics.org: An openfree genomics portal. NHGRI: US government's genome institute ... Biology portal Cognitive genomics Computational genomics Epigenomics Functional genomics GeneCalling, an mRNA profiling ... ENCODE threads explorer Machine learning approaches to genomics. Nature (journal) Global map of genomics laboratories Genomics ... The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional ...
https://en.wikipedia.org/wiki/Genomics
Structural genomicsStructural genomics
... can be used to predict novel protein folds based on other structural data. Structural genomics can also ... A Science article from January 2006 analyzes the structural genomics field. One advantage of structural genomics, such as the ... The principal difference between structural genomics and traditional structural prediction is that structural genomics attempts ... for annotating protein structures emerging from high-throughput structural genomics centers. One goal of structural genomics is ...
https://en.wikipedia.org/wiki/Structural_genomics
CD GenomicsCD Genomics
... , a genomics services company, provides sequencing services, genotyping and library construction by developing ... CD Genomics, is a next-generation sequencing provider that was established in 2004. Equipped with both traditional and modern ... Scientists from CD Genomics have participated in many genome projects, such as Illumina, the genome sequence, DNA analyzer, ... In 2007, CD Genomics expanded its services to molecular biology research.[citation needed] Bager, Ragnhild J.; Kudirkiene, Egle ...
https://en.wikipedia.org/wiki/CD_Genomics
Genomics (journal)Genomics (journal)
Genomics is a peer-reviewed scientific journal in genomics, publishing articles on topics such as comparative genomics, ... Genomics author instructions. Accessed 18 Aug 2009. Genomics. Entrez NLM Catalog. Accessed 18 Aug 2009. Official website v t e ... functional genomics, association studies, regulatory DNA elements, and genetics on a genome-wide scale. The journal was ... Genomics journals, All stub articles, Genetics journal stubs). ... MEDLINE Science Citation Index Expanded Scopus Genomics ...
https://en.wikipedia.org/wiki/Genomics_(journal)
Chordate genomicsChordate genomics
The deep branching of chordate phylogeny has been clarified by chordate genomics. Chordate genomics demonstrates that the ... Chordate genomics is the study of the evolution of the chordate clade based on a comparison of the genomes of several species ... Nature 453 1064-1071, (2008) v t e v t e (Genomics, All stub articles, Chordate stubs, Genetics stubs). ...
https://en.wikipedia.org/wiki/Chordate_genomics
Computational genomicsComputational genomics
... this field is also often referred to as Computational and Statistical Genetics/genomics. As such, computational genomics may be ... The final Computational Genomics conference was held in 2006, featuring a keynote talk by Nobel Laureate Barry Marshall, co- ... "Computational Genomics and Proteomics at MIT". Archived from the original on 2018-03-22. Retrieved 2006-12-29. Mount D (2000). ... Computational genomics refers to the use of computational and statistical analysis to decipher biology from genome sequences ...
https://en.wikipedia.org/wiki/Computational_genomics
Color GenomicsColor Genomics
"20 Minutes With: Color Genomics CEO Othman Laraki". www.barrons.com. Retrieved 2022-02-18. "Color valuation reaches $4.6B with ... All articles with unsourced statements, Articles with unsourced statements from March 2022, Genomics companies, Genetics, ... Siwicki, Bill (October 24, 2019). "Jefferson Health combines genomics, population health to enhance employee wellness". ...
https://en.wikipedia.org/wiki/Color_Genomics
10x Genomics10x Genomics
... were ordered to pay $24 million in damages to Bio-Rad and a 15% royalty on sales. 10x Genomics appealed the ... "Buzzy Startup 10x Genomics Buys Spatial Transcriptomics In Bet On Genetic Tools". Forbes. Retrieved 2019-01-28. "10X Genomics ... "10x Genomics' IPO rockets past a $390M raise". FierceBiotech. Retrieved 2019-10-07. Hepler, Lauren. "10x Genomics takes gene ... Farr, Christina (2018-08-28). "SoftBank-backed 10x Genomics buys pinomics". www.cnbc.com. Retrieved 2019-01-28. "10x Genomics ...
https://en.wikipedia.org/wiki/10x_Genomics
Nutritional genomicsNutritional genomics
... or Nutrigenomics is the relation between food and inherited genes, it was first expressed in 2001. The ... Nutritional genomics, also known as nutrigenomics, is a science studying the relationship between human genome, human nutrition ... Obesity is one of the most widely studied topics in nutritional genomics. Due to genetic variations among individuals, each ... There are several applications for nutritional genomics, for example how much nutritional intervention and therapy can ...
https://en.wikipedia.org/wiki/Nutritional_genomics
Empire GenomicsEmpire Genomics
"Empire Genomics building a new $1.2M lab". Buffalo Business First. Retrieved 27 December 2012. "Empire Genomics Creating 50 ... "Biocare Medical Acquires Empire Genomics". NS Medical Devices. 2022-11-23. Retrieved 2022-11-23. Empire Genomics on Twitter ... In 2012, Empire Genomics released a test for multiple myeloma and opened a new laboratory to focus on the test. As of 2012, ... Empire Genomics is a cancer molecular diagnostics company. They make genetic tests for over 200 different types of health ...
https://en.wikipedia.org/wiki/Empire_Genomics
Genomics EnglandGenomics England
"Professor Ewan Birney appointed to the Genomics England Board , Genomics England". Genomics England. 26 May 2016. Retrieved 6 ... "Chris Wigley appointed CEO of Genomics England , Genomics England". 26 July 2019. "GENOMICS ENGLAND LIMITED". Companies House. ... "Genomics England - How we work". Genomics England Limited. Retrieved 3 April 2021. "NHS England » New NHS centres add their ... it is hoped that Genomics England will also mark the beginnings of a UK genomics industry and the start of a personalised ...
https://en.wikipedia.org/wiki/Genomics_England
Cofactor GenomicsCofactor Genomics
... St. Louis Business Journal: St. Louis startup Cofactor to sequence Ozzy's genome [2] "Cofactor Genomics ... Cofactor Genomics was founded in August 2008 by Jarret Glasscock, Matt Hickenbotham, and Ryan Richt. The technological advances ... Cofactor Genomics is a biotech company that primarily focuses on drug development, medical research, and personalized medicine ... In November 2013, Cofactor Genomics opened a 10,000 ft2 headquarters in St. Louis, MO. The company also has offices in San ...
https://en.wikipedia.org/wiki/Cofactor_Genomics
Nebula GenomicsNebula Genomics
... was co-founded in 2018 by George Church, geneticist at Harvard Medical School. In August 2018, Nebula Genomics ... Nebula Genomics is a personal genomics company based in San Francisco, California. It offers a whole-genome sequencing service ... although nowadays Nebula Genomics states in its FAQs that the samples are sequenced in Europe. Nebula Genomics said that this ... In 2019, Nebula Genomics won the "Best-in-Show" award at the SXSW Pitch competition, part of the South by Southwest festival. " ...
https://en.wikipedia.org/wiki/Nebula_Genomics
Landscape genomicsLandscape genomics
... is a relatively new field, made possible by recent technological advances in genetic mapping. Genomics is ... Landscape genomics analyzes adaptive markers, whereas landscape genetics only analyzes neutral markers. The field of genomics ... Landscape genomics makes use of several fields of study. Environmental association analysis is used to link adaptive processes ... Landscape genomics is one of many strategies used to identify relationships between environmental factors and the genetic ...
https://en.wikipedia.org/wiki/Landscape_genomics
Cambrian GenomicsCambrian Genomics
... maintained that it could make any life form by laser printing DNA. It was able to print DNA for companies ... Cambrian Genomics was a biotechnology company based in San Francisco which used a laser-based technique to synthesize DNA. ... In 2014, Cambrian Genomics raised a $10 million round of funding intended for printing DNA for customers in the industrial ... Cambrian Genomics produced genetic material for a 2013 effort to produce genetically modified glowing plants for sale to the ...
https://en.wikipedia.org/wiki/Cambrian_Genomics
Psychosocial genomicsPsychosocial genomics
... (PG) is a field of research first proposed by Ernest L. Rossi in 2002. PG examines the modulation of gene ... Psychosocial genomics focuses on the how the highly personal and subjective states of human consciousness can modulate gene ... Ernest L. Rossi describes the new science[clarification needed] of Psychosocial Genomics: "I call this new perspective on the ... Rossi, E. L., & Rossi, K. L. (2013). Creating New Consciousness in Everyday Life - The Psycho-Social Genomics of Self Creation ...
https://en.wikipedia.org/wiki/Psychosocial_genomics
Personal genomicsPersonal genomics
... or consumer genetics is the branch of genomics concerned with the sequencing, analysis and interpretation of ... BMC Genomics. 16 (910): 910. doi:10.1186/s12864-015-1973-7. PMC 4636840. PMID 26547235. "Is Preventive Genomics Elitist?". 21 ... Public Health Genomics. Retrieved 20 February 2017/ Corpas, Manuel (6 January 2012). "A Family Experience of Personal Genomics ... In 2009, Complete Genomics of Mountain View announced that it would provide full genome sequencing for $5,000, from June 2009. ...
https://en.wikipedia.org/wiki/Personal_genomics
Ontario GenomicsOntario Genomics
... , formerly the Ontario Genomics Institute, is a not-for-profit organization that manages genomics research ... Ontario Genomics is funded by the Ontario government and the federal research funding agency Genome Canada. Ontario Genomics ... Ontario Genomics has: Raised more than $1 billion for genomics research in Ontario and directly supported 7300 R&D jobs Secured ... Ontario Genomics Synthetic Biology Report 2016 Ontario Genomics Health Data Report - Call for a Health Data Ecosystem Genome ...
https://en.wikipedia.org/wiki/Ontario_Genomics
Synthetic genomicsSynthetic genomics
... is unlike genetic modification in the sense that it does not use naturally occurring genes in its life forms ... Synthetic genomics is a nascent field of synthetic biology that uses aspects of genetic modification on pre-existing life forms ... "Synthetic Genomics, Inc. - Our Business". www.syntheticgenomics.com. Retrieved 2015-09-26. Montague, Michael G; Lartigue, ... The development of synthetic genomics is related to certain recent technical abilities and technologies in the field of ...
https://en.wikipedia.org/wiki/Synthetic_genomics
Complete GenomicsComplete Genomics
In March 2013 Complete Genomics was acquired by BGI-Shenzhen, a genomics services company in Shenzhen, Guangdong, China. After ... a spinoff of Complete Genomics' consumer division. In February 2009, Complete Genomics announced that it had sequenced its ... Complete Genomics is a life sciences company that has developed and commercialized a DNA sequencing platform for human genome ... In 2016, Complete Genomics contributed over 184 phased human genomes to George Church's Personal Genome Project. In 2019, they ...
https://en.wikipedia.org/wiki/Complete_Genomics
BMC GenomicsBMC Genomics
... Retrieved 9 January 2019. "BMC Genomics". BMC Genomics. Retrieved 2020-01-20. v t e (Articles with short ... BMC Genomics is an open-access scientific journal covering all areas of genomics and proteomics. The journal was established in ... "BMC Genomics". BMC Genomics. Retrieved 2020-01-20. "About". biomedcentral.com. ... Genomics journals, All stub articles, Genetics journal stubs). ...
https://en.wikipedia.org/wiki/BMC_Genomics
Rosetta GenomicsRosetta Genomics
"Rosetta Genomics sold for $10m". Globes (in Hebrew). 2017-12-17. Retrieved 2020-07-20. Rosetta Genomics Files for Chapter 7 ... "Rosetta Genomics, Ltd--ROSG: To Work In Collaboration With NYU Medical Center," Knobias, September 7, 2007. "Rosetta Genomics ... Rosetta Genomics has developed a microRNA discovery process. Rosetta Genomics has developed several proprietary technologies ... Also in January 2008, Rosetta Genomics announced that its subsidiary, Rosetta Genomics Inc. has received a license to use Roche ...
https://en.wikipedia.org/wiki/Rosetta_Genomics
Phase GenomicsPhase Genomics
In 2018, Phase Genomics received a $1.5 million SBIR grant from the National Institute of Allergy and Infectious Diseases ( ... Phase Genomics developed a library preparation kit for the Hi-C sequencing method previously developed by researchers Job ... In 2020, Phase Genomics received 2 grants totaling $3.9 million from the National Human Genome Research Institute and the ... Phase Genomics is an American biotechnology company based in Seattle, Washington. The company develops proximity ligation kits ...
https://en.wikipedia.org/wiki/Phase_Genomics
Comparative genomicsComparative genomics
See also: History of genomics Comparative genomics has a root in the comparison of virus genomes in the early 1980s. For ... Touchman, J. (2010). "Comparative Genomics". Nature Education Knowledge. 3 (10): 13. Xia, X. (2013). Comparative Genomics. ... Comparative genomics is a field of biological research in which the genomic features of different organisms are compared. The ... Applying a comparative genomics approach by analyzing the genomes of several related pathogens can lead to the development of ...
https://en.wikipedia.org/wiki/Comparative_genomics
TREC GenomicsTREC Genomics
TREC, the Text Retrieval Conference The TREC Genomics track web site v t e (Genomics organizations, All stub articles, Genetics ... The TREC Genomics track was a workshop held under the auspices of NIST for the purpose of evaluating systems for information ... The TREC Genomics track took place annually from 2003 to 2007, with some modifications to the task set every year; tasks ... retrieval and related technologies in the genomics domain. ...
https://en.wikipedia.org/wiki/TREC_Genomics
Cognitive genomicsCognitive genomics
... (or neurative genomics) is the sub-field of genomics pertaining to cognitive function in which the genes and ... Genomics Neurogenetics Comparative genomics Genetics Evolutionary biology Molecular biology Cognitive psychology Behavioral ... In genomics, a gene being imaged and analyzed is referred to as a candidate gene. The ideal candidate genes for comparative ... By applying comparative genomics, the genomes of multiple species are compared in order to identify genetic and phenotypical ...
https://en.wikipedia.org/wiki/Cognitive_genomics
Tute GenomicsTute Genomics
... is a genomics startup that provides a cloud-based web application for rapid and accurate annotation of human ... "Tute Genomics Joins the Global Alliance for Genomics and Health". article.wn.com. Retrieved 1 March 2015. "Commercial Launch of ... Tute Genomics was acquired by PierianDX in 2016. 2013 Tute Genomics launched in 2013 and entered the accelerator, BoomStartup. ... "Tute Genomics Inks NGS Test Analytics Deal with Lineagen". Genomeweb.com. Retrieved 1 March 2015. "Tute Genomics Biomarker ...
https://en.wikipedia.org/wiki/Tute_Genomics
Population genomicsPopulation genomics
Genomics Landscape genomics Personal genomics Population groups in biomedicine Luikart, G.; England, P. R.; Tallmon, D.; Jordan ... Population genomics is the large-scale comparison of DNA sequences of populations. Population genomics is a neologism that is ... Population Genomics from Nature Education The Simple Fool's Guide to Population Genomics via RNA-Seq Drosophila Population ... population genomics allows us to learn about the species' genetic differences. In the human population, population genomics has ...
https://en.wikipedia.org/wiki/Population_genomics
Personalized genomicsPersonalized genomics
The order of nucleotides determines the genomics of individuals, and individuals have different genomics . Therefore, people ... To analyze personal genomics, a technique called DNA sequencing is needed and it is used to determine any disorders or ... Personalized genomics includes the analysis of the genome of individuals. To analyze the genome, a basic knowledge of genetics ... Whole exome sequencing is the method to sequence all exons in genomics. As proteins produced by the exons are crucial for human ...
https://en.wikipedia.org/wiki/Personalized_genomics
Current GenomicsCurrent Genomics
... is a peer-reviewed scientific journal covering all aspects of genomics. It was established in 2000 with Stefan ... "Current Genomics". 2019 Journal Citation Reports. Clarivate. 2020. Official website (Articles with short description, Short ...
https://en.wikipedia.org/wiki/Current_Genomics
Public Health Genomics | CDCPublic Health Genomics | CDC
The mission of the Office of Genomics and Precision Public Health is to integrate advances in genomics and precision health ... Source: National Center on Birth Defects and Developmental Disabilities, Office of Genomics and Precision Public Health ...
https://www.cdc.gov/genomics
precision medicineprecision medicine
Genomics and Precision Health - precision medicine - Genomics and Precision Health Blog ... What should be the public health priorities in genomics and precision medicine in the next decade?. The CDC Office of Genomics ... Genomics and Health Equity: Reaching Asian American, Native Hawaiian, and Pacific Islander Communities. On April 29, 2022, ... What is the Role of Public Health in Addressing Health Equity in Genomics and Precision Medicine?. The following are excerpts ...
https://blogs.cdc.gov/genomics/category/precision-medicine/
FDA Creates New Genomics PositionFDA Creates New Genomics Position
The Food and Drug Administration said this week it is creating a new position for coordinating genomics activities in its ... "The FDAs emphasis on a coordinated genomics effort is the outcome of the June 2008 FDA Symposium and Retreat on Genomics, the ... Appointed to the new position of "Senior Genomics Advisor" is Liz Mansfield, who was previously with the agencys Center for ... Cite this: Kathryn Foxhall . FDA Creates New Genomics Position - Medscape - Feb 06, 2009. ...
https://www.medscape.com/viewarticle/587963
Browsing WHA55 by Subject GenomicsBrowsing WHA55 by Subject "Genomics"
JavaScript is disabled for your browser. Some features of this site may not work without it ...
https://apps.who.int/iris/handle/10665/78090/browse?authority=Genomics&type=mesh
ABRF Genetics & Genomics News | GenomeWebABRF Genetics & Genomics News | GenomeWeb
Single-cell Genomics Studies Enable Detailed Look into Tumor, Immune Cells, ABRF Speakers Say ... In Brief This Week: T2 Biosystems, Novacyt, OpGen, Dante Genomics, Nautilus Biotechnology, More ... New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More ...
https://www.genomeweb.com/organization/abrf
Genomics and world healthGenomics and world health
2004)‎. Genomics and world health. World Health Organization. https://extranet.who.int/iris/restricted/handle/10665/20055 ...
https://extranet.who.int/iris/restricted/handle/10665/20055
The end of the deCODEme personal genomics service? | ScienceBlogsThe end of the deCODEme personal genomics service? | ScienceBlogs
This piece in Newsweek is a neat summary of the rise and fall of Icelandic genomics giant deCODE Genetics. Regular readers of ... The end of the (deCODEme) personal genomics service excellent entry is actually a double question (when parentheses are used). ... This piece in Newsweek is a neat summary of the rise and fall of Icelandic genomics giant deCODE Genetics. Regular readers of ... The loss of deCODEme would mean the end of one of the "Big Three" personal genomics companies out there right now; and there ...
https://scienceblogs.com/geneticfuture/2010/02/14/the-end-for-the-decodeme-perso
PCR purification - Genomics Core Facility (UPF)PCR purification - Genomics Core Facility (UPF)
Breeding, Genetics and Genomics - Southern Cross UniversityBreeding, Genetics and Genomics - Southern Cross University
Crop Genetics and Genomics. Crop genomics research at Southern Cross Plant Science provides a window into the genetic factors ... Breeding, Genetics and Genomics. Global Niche Crops. Australia is exceptionally well-placed to address the growing global ... Located at Lismore, at the confluence of several major bioregions, and with its world class genomics and plant chemistry ... Ongoing work includes integration of information to allow navigation via comparative genomics from genetics loci to chromosome ...
https://www.scu.edu.au/southern-cross-plant-science/research/breeding-genetics-and-genomics/
WHO EMRO | Genomics | Health topics
MAXIMUM 150 WORDS: Remember: front load your paragraphs! This content should include a strong opening sentence describing the health topic in the Eastern Mediterranean (include key words "Eastern Mediterranean" and health topic name for search engine optimization). You should focus on the issue as it relates to the Region and the magnitude of problem in the region, as well as a brief mention of current situation/problem.. ...
http://www.emro.who.int/health-topics/genomics/
Adding or Expanding Data Fields Collected by the Cancer Registry | Cancer Genomics Program | CDCAdding or Expanding Data Fields Collected by the Cancer Registry | Cancer Genomics Program | CDC
Utah genomics program staff, the state cancer registry, and genetic counselors from two large health care systems worked ... The cost of the activity included genomics program staff time and a subcontract with the registry to pay staff to perform ...
https://www.cdc.gov/cancer/genomics/collaborating-with-registries/data-fields.htm
Sol Genomics Network
To reset your password, please enter your email address. A link will be sent to that address with a link that will enable you to reset your password ...
https://www.sgn.cornell.edu/gem/target.pl?id=138
ROSGQ - Rosetta Genomics Ltd Stock Price Quote - PINX | MorningstarROSGQ - Rosetta Genomics Ltd Stock Price Quote - PINX | Morningstar
See the latest Rosetta Genomics Ltd stock price (PINX:ROSGQ), related news, valuation, dividends and more to help you make your ... FAQs for Rosetta Genomics Ltd Stock Does ROSGQ pay dividends? If so, how much? ... How big is Rosetta Genomics Ltd? ROSGQs market cap is 592.99. Market capitalization is calculated by taking a companys share ... Rosetta Genomics Ltd is an Israel based genomic diagnostics company operating globally. It is focused on research and ...
https://www.morningstar.com/stocks/pinx/rosgq/quote
Proximal tubular dysfunction related to tenofovir in people... : Pharmacogenetics and GenomicsProximal tubular dysfunction related to tenofovir in people... : Pharmacogenetics and Genomics
Pharmacogenetics and Genomics 32(9):p 293-300, December 2022. , DOI: 10.1097/FPC.0000000000000482 ... Thought you might appreciate this item(s) I saw in Pharmacogenetics and Genomics.. ... Thought you might appreciate this item(s) I saw in Pharmacogenetics and Genomics.. ... Thought you might appreciate this item(s) I saw in Pharmacogenetics and Genomics.. ...
https://journals.lww.com/jpharmacogenetics/Abstract/2022/12000/Proximal_tubular_dysfunction_related_to_tenofovir.1.aspx
Compressive genomics | Nature BiotechnologyCompressive genomics | Nature Biotechnology
Box 1: Compressive genomics using BLAST and BLAT. We describe versions of the widely used BLAST and BLAT algorithms that ... Compressive algorithms for genomics have the great advantage of becoming proportionately faster with the size of the available ... As proof of principle for the underlying idea of compressive genomics, we present model compressive algorithms that run BLAST ... the compressive genomic paradigm will become critical to fully realizing the potential of large-scale genomics. ...
https://www.nature.com/articles/nbt.2241?error=cookies_not_supported&code=5a16cb7d-ea7d-4478-b517-35a71eb78501
Figure 3 - Use of Genomics to Investigate Historical Importation of Shiga Toxin-Producing Escherichia coli Serogroup O26 and...
Use of Genomics to Investigate Historical Importation of Shiga Toxin-Producing Escherichia coli Serogroup O26 and Nontoxigenic ... Use of Genomics to Investigate Historical Importation of Shiga Toxin-Producing Escherichia coli Serogroup O26 and Nontoxigenic ...
https://wwwnc.cdc.gov/eid/article/25/3/18-0899-f3
Institute for Environmental GenomicsInstitute for Environmental Genomics
... and Director of the Institute for Environmental Genomics. Dr. Zhou is an international leader in genomics-enabled microbial ... Institute for Environmental Genomics. 101 David L Boren Blvd. Norman, OK 73019 ... Updated 11/25/2022 by Institute for Environmental Genomics: [email protected] ... Biological and Environmental Sciences Honored for his outstanding accomplishments in environmental genomics and microbial ...
https://www.ou.edu/ieg/
Genomics and ProteomicsGenomics and Proteomics
BRCA1/2-deficient ovarian carcinoma (OC) has been shown to be particularly sensitive to poly (ADP-ribose) polymerase inhibitors (PARPis). Furthermore, BRCA1/2 mutation status is currently used as a predictive biomarker for PARPi therapy. Despite providing a major clinical benefit to the majority of patients, a significant proportion of BRCA1/2-deficient OC tumors do not respond to PARPis for reasons that are incompletely understood. Using an integrated chemical, phospho- and ADP-ribosylation proteomics approach, we sought here to develop additional mechanism-based biomarker candidates for PARPi therapy in OC and identify new targets for combination therapy to overcome primary resistance ...
https://www.jbc.org/Genomics-Proteomics?startPage=&Ppub=%5B20211124%20TO%2020221124%5D
Genomics: Junking the junk DNA | New ScientistGenomics: Junking the junk DNA | New Scientist
Is most of our DNA really rubbish that doesnt code for anything? The best way to find out is by deleting it
https://www.newscientist.com/article/mg19526121-500-genomics-junking-the-junk-dna/
Genomics - Technology Facility, University of YorkGenomics - Technology Facility, University of York
... using both 10X Genomics and Nanostring systems. Please contact members of the Genomics ([email protected]) or Imaging ( ... The genomics lab provides access and training to our users in the use of qPCR. We maintain and run three qPCR instruments: ... The genomics lab can provide end-to-end support, from experimental design through to analysis (working with members of our data ... The Genomics, Imaging and Cytometry and Data Science labs work together to support a range of spatial analysis platforms as ...
https://www.york.ac.uk/biology/technology-facility/genomics/
Global Health Brief: Prognostic Genomics and Breast CancerGlobal Health Brief: Prognostic Genomics and Breast Cancer
Download Prognostic Genomics and Breast Cancer The Author. * Dr. Elizabeth Gil Aguilar Medical Manager - Health, Latin ...
https://www.rgare.com/knowledge-center/media/articles/global-health-brief-prognostic-genomics-and-breast-cancer
Cerebral palsy and genomics: an international consortiumCerebral palsy and genomics: an international consortium
... Dev Med Child Neurol. 2018 Feb;60(2):209-210. doi: 10.1111/dmcn.13643 ... 3 Department of Health, Public Health Division, Office of Population Health Genomics, Government of Western Australia, Perth, ... 14 The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada. ... members of the International Cerebral Palsy Genomics Consortium ...
https://pubmed.ncbi.nlm.nih.gov/29336076/
USPTO Genetics & Genomics News | GenomeWebUSPTO Genetics & Genomics News | GenomeWeb
This week, the US PTAB found that some claims of a Personal Genomics patent for single-molecule detection didnt hold up, while ... Illumina had argued that Complete Genomics patent covering two-color sequencing-by-synthesis chemistry was obvious, but the US ... New Products Posted to GenomeWeb: Thermo Fisher, Element Biosciences, Dante Genomics, More ...
https://www.genomeweb.com/organization/uspto
Key Terms | GenomicsKey Terms | Genomics
Genomics: The study of the genome. Genomics aims to understand how our DNA functions and interacts within our bodies.. Genetics ... Precision Genomics: A service line of Intermountain Healthcare centered on the study of genomics to personalize care for ... Pharmacogenomics: A cutting-edge field of genomics that studies how genes can influence a persons response to medication. ... Watch the stories of patients like you, who live the healthiest lives possible thanks to Intermountain Precision Genomics. ...
https://intermountainhealthcare.org/services/genomics/patients/dna/key-terms/
Genetics and GenomicsGenetics and Genomics
Human and Mammalian Genetics and Genomics: The 64th McKusick Short Course Precision medicine, Ethics, Stem cells, Microbiome, ... Endocrinology, Genetic Tools, Rare Diseases, Neurodegenerative Disease, Cancer/Tumors, Genetics and Genomics, Cancer ... Genetic Tools, Reproductive Biology, Fertility Research, Resource Development and Dissemination, Genetics and Genomics, ... Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative ...
https://www.jax.org/research-and-faculty/genetics-and-genomics
Privacy in GenomicsPrivacy in Genomics
When conducting genomics research, two essential values of scientific research should be balanced:. *the need to share data ... When conducting genomics research, two essential values of scientific research should be balanced:. *the need to share data ... Genomics in Law Enforcement. Genetic and genomic information is used by law enforcement to investigate criminal acts and within ... Genomics in Law Enforcement. Genetic and genomic information is used by law enforcement to investigate criminal acts and within ...
https://www.genome.gov/about-genomics/policy-issues/Privacy
Medical Genetics and Genomics Residency ProgramMedical Genetics and Genomics Residency Program
Zhang Pregnancy Genomics Lab | Human GeneticsZhang Pregnancy Genomics Lab | Human Genetics
The Ge Zhang laboratory studies pregnancy genomics to define the mechanism controlling the timing for birth in humans. ... Zhang Pregnancy Genomics Research Lab. The laboratory of Ge Zhang, PhD, studies pregnancy genomics to define the mechanism ... Genomics and Development. Six Gene Loci Associated with Gestational Duration. Louis J. Muglia, MD, PhD, Ge Zhang, MD, PhD7/1/ ... The Zhang Pregnancy Genomics Laboratory has analyzed mice with corticotropin-releasing hormone (CRH) deficiency to determine ...
https://www.cincinnatichildrens.org/research/divisions/h/genetics/labs/zhang
nsf21546 Enabling Discovery through GEnomics (EDGE) | NSF - National Science Foundation
Enabling Discovery through GEnomics (EDGE) Available Formats: HTML , PDF Document Type: Program Announcements & Information. ...
https://nsf.gov/publications/pub_summ.jsp?org=IOS&ods_key=nsf21546
Genomics | The Scientist Magazine®Genomics | The Scientist Magazine®
Genomics. Edited by: Steve Bunk A. Goffeau, B.G. Barrell, H. Bussey, R.W. Davis, B. Dujon, H. Feldmann, F. Galibert, J.D. ...
https://www.the-scientist.com/hot-paper/genomics-56585

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