The external and internal organs related to reproduction.
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
The female reproductive organs. The external organs include the VULVA; BARTHOLIN'S GLANDS; and CLITORIS. The internal organs include the VAGINA; UTERUS; OVARY; and FALLOPIAN TUBES.
An erectile structure homologous with the penis, situated beneath the anterior labial commissure, partially hidden between the anterior ends of the labia minora.
In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure to abnormal levels of GONADAL HORMONES in the maternal environment, or disruption of the function of those hormones by ENDOCRINE DISRUPTORS are included.
A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.
Development of male secondary SEX CHARACTERISTICS in the FEMALE. It is due to the effects of androgenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.
The process in developing sex- or gender-specific tissue, organ, or function after SEX DETERMINATION PROCESSES have set the sex of the GONADS. Major areas of sex differentiation occur in the reproductive tract (GENITALIA) and the brain.
A cutaneous pouch of skin containing the testicles and spermatic cords.
A type of defective gonadal development in patients with a wide spectrum of chromosomal mosaic variants. Their karyotypes are of partial sex chromosome monosomy resulting from an absence or an abnormal second sex chromosome (X or Y). Karyotypes include 45,X/46,XX; 45,X/46,XX/47,XXX; 46,XXp-; 45,X/46,XY; 45,X/47,XYY; 46,XYpi; etc. The spectrum of phenotypes may range from phenotypic female to phenotypic male including variations in gonads and internal and external genitalia, depending on the ratio in each gonad of 45,X primordial germ cells to those with normal 46,XX or 46,XY constitution.
Congenital conditions in individuals with a male karyotype, in which the development of the gonadal or anatomical sex is atypical.
A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.
The processes of anatomical and physiological changes related to sexual or reproductive functions during the life span of a human or an animal, from FERTILIZATION to DEATH. These include SEX DETERMINATION PROCESSES; SEX DIFFERENTIATION; SEXUAL MATURATION; and changes during AGING.
Sexual union of a male and a female in non-human species.
Validation of the SEX of an individual by inspection of the GONADS and/or by genetic tests.
Pathological processes of the VULVA.
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
The 46,XX gonadal dysgenesis may be sporadic or familial. Familial XX gonadal dysgenesis is transmitted as an autosomal recessive trait and its locus was mapped to chromosome 2. Mutation in the gene for the FSH receptor (RECEPTORS, FSH) was detected. Sporadic XX gonadal dysgenesis is heterogeneous and has been associated with trisomy-13 and trisomy-18. These phenotypic females are characterized by a normal stature, sexual infantilism, bilateral streak gonads, amenorrhea, elevated plasma LUTEINIZING HORMONE and FSH concentration.
Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
A disorder of sexual development transmitted as an X-linked recessive trait. These patients have a karyotype of 46,XY with end-organ resistance to androgen due to mutations in the androgen receptor (RECEPTORS, ANDROGEN) gene. Severity of the defect in receptor quantity or quality correlates with their phenotypes. In these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in Reifenstein Syndrome, to that of a normal male with INFERTILITY.
Abnormal number or structure of the SEX CHROMOSOMES. Some sex chromosome aberrations are associated with SEX CHROMOSOME DISORDERS and SEX CHROMOSOME DISORDERS OF SEX DEVELOPMENT.
Pathological processes involving the PENIS or its component tissues.
All the organs involved in reproduction and the formation and release of URINE. It includes the kidneys, ureters, BLADDER; URETHRA, and the organs of reproduction - ovaries, UTERUS; FALLOPIAN TUBES; VAGINA; and CLITORIS in women and the testes; SEMINAL VESICLES; PROSTATE; seminal ducts; and PENIS in men.
A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.
A number of syndromes with defective gonadal developments such as streak GONADS and dysgenetic testes or ovaries. The spectrum of gonadal and sexual abnormalities is reflected in their varied sex chromosome (SEX CHROMOSOMES) constitution as shown by the karyotypes of 45,X monosomy (TURNER SYNDROME); 46,XX (GONADAL DYSGENESIS, 46XX); 46,XY (GONADAL DYSGENESIS, 46,XY); and sex chromosome MOSAICISM; (GONADAL DYSGENESIS, MIXED). Their phenotypes range from female, through ambiguous, to male. This concept includes gonadal agenesis.
The primary testis-determining gene in mammalians, located on the Y CHROMOSOME. It codes for a high mobility group box transcription factor (TRANSCRIPTION FACTORS) which initiates the development of the TESTES from the embryonic GONADS.
A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.
Congenital structural abnormalities of the UROGENITAL SYSTEM in either the male or the female.
A dilated cavity extended caudally from the hindgut. In adult birds, reptiles, amphibians, and many fishes but few mammals, cloaca is a common chamber into which the digestive, urinary and reproductive tracts discharge their contents. In most mammals, cloaca gives rise to LARGE INTESTINE; URINARY BLADDER; and GENITALIA.
Clinical conditions caused by an abnormal sex chromosome constitution (SEX CHROMOSOME ABERRATIONS), in which there is extra or missing sex chromosome material (either a whole chromosome or a chromosome segment).
A suborder of HEMIPTERA, called true bugs, characterized by the possession of two pairs of wings. It includes the medically important families CIMICIDAE and REDUVIIDAE. (From Dorland, 28th ed)
An ester of TESTOSTERONE with a propionate substitution at the 17-beta position.
The body region lying between the genital area and the ANUS on the surface of the trunk, and to the shallow compartment lying deep to this area that is inferior to the PELVIC DIAPHRAGM. The surface area is between the VULVA and the anus in the female, and between the SCROTUM and the anus in the male.
Cutaneous lesions arising from infection with Treponema pallidum. In the primary stage, 18-21 days following infection, one or more chancres appear. If untreated, the subsequent stages of the disease appear as syphilids. These eruptions are superficial, nondestructive, exanthematic, transient, macular roseolas that may later be maculopapular or papular polymorphous or scaly, pustular, pigmented eruptions.(Arnold, Odom, and James, Andrew's Diseases of the Skin, 8th ed, p409)
Burns produced by contact with electric current or from a sudden discharge of electricity.
Sexual activities of animals.
A foul-smelling accumulation of SEBUM and desquaminated epidermal cells, especially the cheesy substance found under the foreskin of the penis and at the base of the labia minor near the clitoris.
An enzyme that catalyzes the reduction of TESTOSTERONE to 5-ALPHA DIHYDROTESTOSTERONE.
Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
Peculiarities associated with the internal structure, form, topology, or architecture of organisms that distinguishes them from others of the same species or group.
A complex neoplasm composed of a mixture of gonadal elements, such as large primordial GERM CELLS, immature SERTOLI CELLS or GRANULOSA CELLS of the sex cord, and gonadal stromal cells. Gonadoblastomas are most often associated with gonadal dysgenesis, 46, XY.
The external genitalia of the female. It includes the CLITORIS, the labia, the vestibule, and its glands.
An inherited condition characterized by multiple malformations of CARTILAGE and bone including CRANIOSYNOSTOSIS; midface hypoplasia; radiohumeral SYNOSTOSIS; CHOANAL ATRESIA; femoral bowing; neonatal fractures; and multiple joint CONTRACTURES and, occasionally, urogenital, gastrointestinal or cardiac defects. In utero exposure to FLUCONAZOLE, as well as mutations in at least two separate genes are associated with this condition - POR (encoding P450 (cytochrome) oxidoreductase (NADPH-FERRIHEMOPROTEIN REDUCTASE)) and FGFR2 (encoding FIBROBLAST GROWTH FACTOR RECEPTOR 2).
A syndrome characterized by abdominal wall musculature deficiency, cryptorchism, and urinary tract abnormalities. The syndrome derives its name from its characteristic distended abdomen with wrinkled skin.
Mapping of the KARYOTYPE of a cell.
Congenital structural deformities of the upper and lower extremities collectively or unspecified.
Pathological processes involving the female reproductive tract (GENITALIA, FEMALE).
A "smooth brain" malformation of the CEREBRAL CORTEX resulting from abnormal location of developing neurons during corticogenesis. It is characterized by an absence of normal convoluted indentations on the surface of the brain (agyria), or fewer and shallower indentations (pachygryia). There is a reduced number of cortical layers, typically 4 instead of 6, resulting in a thickened cortex, and reduced cerebral white matter that is a reversal of the normal ratio of cerebral white matter to cortex.
An infant during the first month after birth.
Eating other individuals of one's own species.
The occurrence in an individual of two or more cell populations of different chromosomal constitutions, derived from a single ZYGOTE, as opposed to CHIMERISM in which the different cell populations are derived from more than one zygote.
A syndrome characterized by CHRONIC KIDNEY FAILURE and GONADAL DYSGENESIS in phenotypic females with karyotype of 46,XY or female individual with a normal 46,XX karyotype. It is caused by donor splice-site mutations of Wilms tumor suppressor gene (GENES, WILMS TUMOR) on chromosome 11.
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed)
The deposit of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.
A family of large terrestrial carnivores possessing long legs, coarse guard hairs and a busy tail. It is comprised of hyenas and aardwolves.
A characteristic symptom complex.
Inherited disorders that are characterized by subcutaneous and submucosal EDEMA in the upper RESPIRATORY TRACT and GASTROINTESTINAL TRACT.
A genus of cone-nosed bugs of the subfamily TRIATOMINAE. Its species are vectors of TRYPANOSOMA CRUZI.
Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
A pair of ducts near the WOLFFIAN DUCTS in a developing embryo. In the male embryo, they degenerate with the appearance of testicular ANTI-MULLERIAN HORMONE. In the absence of anti-mullerian hormone, mullerian ducts give rise to the female reproductive tract, including the OVIDUCTS; UTERUS; CERVIX; and VAGINA.
Defects in the SEX DETERMINATION PROCESS in 46, XY individuals that result in abnormal gonadal development and deficiencies in TESTOSTERONE and subsequently ANTIMULLERIAN HORMONE or other factors required for normal male sex development. This leads to the development of female phenotypes (male to female sex reversal), normal to tall stature, and bilateral streak or dysgenic gonads which are susceptible to GONADAL TISSUE NEOPLASMS. An XY gonadal dysgenesis is associated with structural abnormalities on the Y CHROMOSOME, a mutation in the GENE, SRY, or a mutation in other autosomal genes that are involved in sex determination.
An acute necrotic infection of the SCROTUM; PENIS; or PERINEUM. It is characterized by scrotum pain and redness with rapid progression to gangrene and sloughing of tissue. Fournier gangrene is usually secondary to perirectal or periurethral infections associated with local trauma, operative procedures, or urinary tract disease.
The human female sex chromosome, being the differential sex chromosome carried by half the male gametes and all female gametes in humans.
INSECTS of the order Coleoptera, containing over 350,000 species in 150 families. They possess hard bodies and their mouthparts are adapted for chewing.
A congenital abnormality characterized by the persistence of the anal membrane, resulting in a thin membrane covering the normal ANAL CANAL. Imperforation is not always complete and is treated by surgery in infancy. This defect is often associated with NEURAL TUBE DEFECTS; MENTAL RETARDATION; and DOWN SYNDROME.
A discipline or occupation concerned with the study of INSECTS, including the biology and the control of insects.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
A chronic inflammatory mucocutaneous disease usually affecting the female genitalia (VULVAR LICHEN SCLEROSUS) and BALANITIS XEROTICA OBLITERANS in males. It is also called white spot disease and Csillag's disease.
The mechanisms by which the SEX of an individual's GONADS are fixed.
A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
A transcription factor that plays an essential role in the development of the TESTES. It is encoded by a gene on the Y chromosome and contains a specific HMG-BOX DOMAIN that is found within members of the SOX family of transcription factors.
A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
The selection or choice of sexual partner in animals. Often this reproductive preference is based on traits in the potential mate, such as coloration, size, or behavioral boldness. If the chosen ones are genetically different from the rejected ones, then NATURAL SELECTION is occurring.
Gross hypo- or aplasia of one or more long bones of one or more limbs. The concept includes amelia, hemimelia, phocomelia, and sirenomelia.
A general term encompassing three types of excision of the external female genitalia - Sunna, clitoridectomy, and infibulation. It is associated with severe health risks and has been declared illegal in many places, but continues to be widely practiced in a number of countries, particularly in Africa.
Cancers or tumors of the PENIS or of its component tissues.
The family Gryllidae consists of the common house cricket, Acheta domesticus, which is used in neurological and physiological studies. Other genera include Gryllotalpa (mole cricket); Gryllus (field cricket); and Oecanthus (tree cricket).
A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.
Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.
The male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in humans and in some other male-heterogametic species in which the homologue of the X chromosome has been retained.
The recording of images in three-dimensional form on a photographic film by exposing it to a laser beam reflected from the object under study.
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
An autosomal dominant disorder with an acronym of its seven features (LENTIGO; ELECTROCARDIOGRAM abnormalities; ocular HYPERTELORISM; PULMONARY STENOSIS; abnormal genitalia; retardation of growth; and DEAFNESS or SENSORINEURAL HEARING LOSS). This syndrome is caused by mutations of PTPN11 gene encoding the non-receptor PROTEIN TYROSINE PHOSPHATASE, type 11, and is an allelic to NOONAN SYNDROME. Features of LEOPARD syndrome overlap with those of NEUROFIBROMATOSIS 1 which is caused by mutations in the NEUROFIBROMATOSIS 1 GENES.
The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.
A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES.
An order of MAMMALS, usually flesh eaters with appropriate dentition. Suborders include the terrestrial carnivores Fissipedia, and the aquatic carnivores PINNIPEDIA.
Formation of differentiated cells and complicated tissue organization to provide specialized functions.
The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellular actions. The complex of the androgen and receptor migrates to the CELL NUCLEUS where it induces transcription of specific segments of DNA.
A birth defect in which the URINARY BLADDER is malformed and exposed, inside out, and protruded through the ABDOMINAL WALL. It is caused by closure defects involving the top front surface of the bladder, as well as the lower abdominal wall; SKIN; MUSCLES; and the pubic bone.
Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth.
The farthest or outermost projections of the body, such as the HAND and FOOT.
The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.
A period in the human life in which the development of the hypothalamic-pituitary-gonadal system takes place and reaches full maturity. The onset of synchronized endocrine events in puberty lead to the capacity for reproduction (FERTILITY), development of secondary SEX CHARACTERISTICS, and other changes seen in ADOLESCENT DEVELOPMENT.
A fibroblast growth factor that preferentially activates FIBROBLAST GROWTH FACTOR RECEPTOR 4. It was initially identified as an androgen-induced growth factor and plays a role in regulating growth of human BREAST NEOPLASMS and PROSTATIC NEOPLASMS.

A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. (1/467)

Morphogenesis depends on the precise control of basic cellular processes such as cell proliferation and differentiation. Wnt5a may regulate these processes since it is expressed in a gradient at the caudal end of the growing embryo during gastrulation, and later in the distal-most aspect of several structures that extend from the body. A loss-of-function mutation of Wnt5a leads to an inability to extend the A-P axis due to a progressive reduction in the size of caudal structures. In the limbs, truncation of the proximal skeleton and absence of distal digits correlates with reduced proliferation of putative progenitor cells within the progress zone. However, expression of progress zone markers, and several genes implicated in distal outgrowth and patterning including Distalless, Hoxd and Fgf family members was not altered. Taken together with the outgrowth defects observed in the developing face, ears and genitals, our data indicates that Wnt5a regulates a pathway common to many structures whose development requires extension from the primary body axis. The reduced number of proliferating cells in both the progress zone and the primitive streak mesoderm suggests that one function of Wnt5a is to regulate the proliferation of progenitor cells.  (+info)

Value of scintigraphy in chronic peritoneal dialysis patients. (2/467)

BACKGROUND: A variety of factors can adversely impact chronic peritoneal dialysis (CPD) as an effective renal replacement therapy for patients with end-stage renal disease. These factors include peritonitis, poor clearances, loss of ultrafiltration, and a variety of anatomic problems, such as hernias, peritoneal fluid leaks, loculations, and catheter-related problems caused by omental blockage. This study reviews our experience with peritoneal scintigraphy for the evaluation of some of these difficulties. METHODS: From 1991 to 1996, 50 peritoneal scintigraphy scans were obtained in 48 CPD patients. Indications for scintigraphy were evaluated, and the patients were placed into four groups: group I, abdominal wall swelling; group II, inguinal or genital swelling; group III, pleural fluid; and group IV, poor drainage and/or poor ultrafiltration. A peritoneal scintigraphy protocol was established and the radiotracer isotope that was used was 2.0 mCi of 99mtechnetium sulfur colloid placed in two liters of 2.5% dextrose peritoneal dialysis solution. RESULTS: Ten scans were obtained to study abdominal wall swelling, with seven scans demonstrating leaks; six of these episodes improved with low-volume exchanges. Twenty scans were obtained to evaluate inguinal or genital swelling, and 10 of these had scintigraphic evidence for an inguinal hernia leak (9 of these were surgically corrected). One of four scans obtained to evaluate a pleural fluid collection demonstrated a peritoneal-pleural leak that corrected with a temporary discontinuation of CPD. Sixteen scans were obtained to assess poor drainage and/or ultrafiltration. Five of these scans demonstrated peritoneal location, and all of these patients required transfer to hemodialysis. The other 11 scans were normal; four patients underwent omentectomies, allowing three patients to continue with CPD. CONCLUSION: Peritoneal scintigraphy is useful in the evaluation and assessment of CPD patients who develop anatomical problems (such as anterior abdominal, pleural-peritoneal, inguinal, and genital leaks) and problems with ultrafiltration and/or drainage.  (+info)

Morphogenesis of the Caenorhabditis elegans male tail tip. (3/467)

Using electron microscopy and immunofluorescent labeling of adherens junctions, we have reconstructed the changes in cell architecture and intercellular associations that occur during morphogenesis of the nematode male tail tip. During late postembryonic development, the Caenorhabditis elegans male tail is reshaped to form a copulatory structure. The most posterior hypodermal cells in the tail define a specialized, sexually dimorphic compartment in which cells fuse and retract in the male, changing their shape from a tapered cone to a blunt dome. Developmental profiles using electron microscopy and immunofluorescent staining suggest that cell fusions are initiated at or adjacent to adherens junctions. Anterior portions of the tail tip cells show the first evidence of retractions and fusions, consistent with our hypothesis that an anterior event triggers these morphogenetic events. Available mutations that interfere with morphogenesis implicate particular regulatory pathways and suggest loci at which evolutionary changes could have produced morphological diversity.  (+info)

Mucosal immune system of the human genital tract. (4/467)

In contrast to the pronounced dominance of secretory IgA over other immunoglobulin isotypes in human saliva, tears, milk, and gastrointestinal fluids, secretions of both female and male genital tracts contain more IgG than secretory IgA. Both IgG and IgA are derived, to a variable degree, from the systemic immunoglobulin pool as well as from local synthesis. The origin of IgG- and IgA-plasma cell precursors destined for the genital tract is unknown, but indirect evidence suggests that mucosal inductive sites localized in the rectum, small intestine, and especially in the nasal cavity contribute such precursors to the female genital tract. Several studies indicated that intranasal immunization of various species, including humans, was efficient at inducing antigen-specific antibody responses in the female genital tract; however, whether this route is also effective in males has not been explored.  (+info)

Exposure to female hormone drugs during pregnancy: effect on malformations and cancer. (5/467)

This study aimed to investigate whether the use of female sex hormone drugs during pregnancy is a risk factor for subsequent breast and other oestrogen-dependent cancers among mothers and their children and for genital malformations in the children. A retrospective cohort of 2052 hormone-drug exposed mothers, 2038 control mothers and their 4130 infants was collected from maternity centres in Helsinki from 1954 to 1963. Cancer cases were searched for in national registers through record linkage. Exposures were examined by the type of the drug (oestrogen, progestin only) and by timing (early in pregnancy, only late in pregnancy). There were no statistically significant differences between the groups with regard to mothers' cancer, either in total or in specified hormone-dependent cancers. The total number of malformations recorded, as well as malformations of the genitals in male infants, were higher among exposed children. The number of cancers among the offspring was small and none of the differences between groups were statistically significant. The study supports the hypothesis that oestrogen or progestin drug therapy during pregnancy causes malformations among children who were exposed in utero but does not support the hypothesis that it causes cancer later in life in the mother; the power to study cancers in offspring, however, was very low. Non-existence of the risk, negative confounding, weak exposure or low study-power may explain the negative findings.  (+info)

Ontogeny of LH receptor gene expression in the pig reproductive tract. (6/467)

In view of the recently documented expression of the LH receptor gene in several nongonadal reproductive tissues, the aim of this study was to analyse further the ontogeny of expression of this gene in the pig reproductive tract in fetal and neonatal life. RT-PCR was used to investigate the expression of the extracellular and transmembrane receptor domains, and to identify the time of onset of transcription of the full-length LH receptor mRNA and its shorter splice variants. Expression of the LH receptor gene was first detected around day 30 of fetal life in both ovary and testis, coinciding with morphological differentiation. The pattern of expression of LH receptor splice variants did not change during postnatal gonadal maturation. Expression of the LH receptor gene in the pig non-gonadal reproductive tract started during fetal life and continued during sexual maturation. A novel pig LH receptor spliced variant, lacking exon 10, was detected for the first time. The transmembrane receptor domain was expressed in fetal tissues, but not in neonatal control tissues. On the basis of the transmembrane domain of the LH receptor mRNA, it is concluded that the ovary and extragonadal tissues of the pig reproductive tract, like the pig testis, synthesize functional LH receptors during fetal life. The presence of LH receptor mRNA in extragonadal reproductive tissues indicates that LH is involved in the control and regulation of reproductive tract maturation.  (+info)

Mammalian reproductive tract mucins. (7/467)

Mucin glycoproteins are major constituents of the glycocalyx that covers mucosal epithelium. Two broad classes of mucins exist: membrane-associated and secretory. Of the secreted mucins, those with cysteine-rich regions are thought to polymerize through disulphide bonds. Among these gel-forming mucins are MUC2, MUC5AC, MUC5B and possibly MUC6. MUC7 lacks cysteine-rich domains and is thought to be secreted as a soluble monomer. Incomplete sequence information prevents classification of other mucins. Tandem repeats of amino acids rich in serine, threonine and proline are a common element in mucin core proteins, giving rise to relatively rigid, linear molecules with great potential for glycosylation. Ten distinct mucin genes have been identified in humans so far. Patterns of expression vary greatly. While MUC9, or oviductin, appears to be restricted to oviduct, the transmembrane mucin MUC1 is widely expressed. Proven functions for the different mucins are largely unknown, although potential functions are addressed in this review. Genetic and protein sequence information and expression profiles are also summarized, followed by a description of mucin assembly. Special attention is given to mucin expression in male and female reproductive tracts.  (+info)

A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1beta. (8/467)

Mutations in the homeodomain-containing transcription factor hepatocyte nuclear factor (HNF)-1beta are the cause of one form of maturity-onset diabetes of the young (MODY), type 5 (MODY5). We have studied a Norwegian family, N5, with a syndrome of mild diabetes, progressive non-diabetic renal disease and severe genital malformations. The sequence of the HNF-1beta gene ( TCF2 ) revealed a 75 bp deletion in exon 2 (409-483del) which would result in the synthesis of a protein lacking amino acids Arg137 to Lys161 (R137-K161del). This deletion is located in the pseudo-POU region of HNF-1beta, a region implicated in the specificity of DNA binding. Functional studies of R137-K161del HNF-1beta revealed that it could not bind an HNF-1 target sequence or stimulate transcription of a reporter gene indicating that this is a loss-of-function mutation. The R137-K161del allele co-segregated with diabetes and renal disease in pedigree N5. In addition, two of four female carriers with this mutation had vaginal aplasia and rudimentary uterus (Mullerian aplasia). These studies strongly suggest that heterozygous mutations in the HNF-1beta gene are associated with a syndrome characterized by MODY and severe, non-diabetic renal disease. Moreover, the presence of internal genital malformations in two females suggests that additional clinical features may be associated with HNF-1beta mutations.  (+info)

External genital development begins with formation of paired genital swellings, which develop into the genital tubercle. Proximodistal outgrowth and axial patterning of the genital tubercle are coordinated to give rise to the penis or clitoris. The genital tubercle consists of lateral plate mesoderm, surface ectoderm, and endodermal urethral epithelium derived from the urogenital sinus. We have investigated the molecular control of external genital development in the mouse embryo. Previous work has shown that the genital tubercle has polarizing activity, but the precise location of this activity within the tubercle is unknown. We reasoned that if the tubercle itself is patterned by a specialized signaling region, then polarizing activity may be restricted to a subset of cells. Transplantation of urethral epithelium, but not genital mesenchyme, to chick limbs results in mirror-image duplication of the digits. Moreover, when grafted to chick limbs, the urethral plate orchestrates morphogenetic ...
J:94932 Satoh Y, Haraguchi R, Wright TJ, Mansour SL, Partanen J, Hajihosseini MK, Eswarakumar VP, Lonai P, Yamada G, Regulation of external genitalia development by concerted actions of FGF ligands and FGF receptors. Anat Embryol (Berl). 2004 Sep;208(6):479-86 ...
The baby with atypical or ambiguous genitalia is usually born in secondary care. For most clinicians, this is an unfamiliar and challenging scenario with the potential for life-long ramifications arising from a consultation led by an unprepared clinician. Language needs to be used carefully with particular clarity when liaising with parents, local health professionals and the specialist multidisciplinary team. Confidence in the recognition and assessment of atypical or ambiguous genitalia in a newborn will guide the local clinician when deciding on the initial investigations required and is a foundation for subsequent management. The local team have key roles in the initial support for parents as well as managing expectations at a time of great uncertainty. There are numerous different diagnoses that can result in atypical or ambiguous genitalia. The clinical findings should guide the initial investigations, and there are many pitfalls when it comes to interpreting the results. The aim of this ...
What are the definitions of genitals and genitalia terms? Learn about the anatomy and physiology of genitals and genitalia in both males and females.
GO Terms Descrition:, DNA binding, nucleus, transcription, DNA-templated, regulation of transcription, DNA-templated, transcription factor binding, programmed cell death, regulation of cell fate specification, negative regulation of Ras protein signal transduction, embryo development ending in birth or egg hatching, locomotion, reproduction, hermaphrodite genitalia development, negative regulation of vulval development, sequence-specific DNA binding transcription factor activity, transcription factor complex, cell cycle ...
Biological Process: abortive mitotic cell cycle; activation of MAPK activity; axon guidance; Bergmann glial cell differentiation; brain development; cellular response to epidermal growth factor stimulus; cerebellar cortex formation; DNA damage checkpoint; ephrin receptor signaling pathway; epidermal growth factor receptor signaling pathway; ERBB signaling pathway; fibroblast growth factor receptor signaling pathway; genitalia development; glucose homeostasis; heart development; homeostasis of number of cells within a tissue; hormone metabolic process; hormone-mediated signaling pathway; inner ear development; integrin-mediated signaling pathway; leukocyte migration; microvillus organization; multicellular organism growth; multicellular organismal reproductive process; negative regulation of cell adhesion mediated by integrin; negative regulation of cortisol secretion; negative regulation of growth hormone secretion; negative regulation of insulin secretion; nerve growth factor receptor signaling ...
Dear Readers,. Like fingerprints, genitalia are unique from person to person, including those who are intersex. Someone with an intersex condition could have external genitalia that are ambiguous or their genitalia might be different from their genetic sex. They could have female genitalia on the outside but be genetically male, they may have both testes and ovaries, or they may have some other combination where the lines between male and female organs are blurred. Also called disorders of sexual development (DSDs), these conditions can be due to genetic or hormonal irregularities. Sometimes DSDs are noticed at birth, while others may not be detected until puberty. Some people might simply ignore irregularities and never seek care, or they may never even realize they have discrepant genitalia. Its hard to say how common it is to have an intersex condition because every case of intersex is different. If you had to put a number on it, though, most estimates are around 1 in 2000 live births to 1 ...
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Addresses ones teeth Herpes inspections, syndrome, hazards, difficulty simply to avoidance. My factor. HSV-1 may possibly also infect the very genitals and can turn into resulting from oral-genital come into contact with during the course of ones teeth sexual intercourse or genital-genital come into contact with during the course of genital or anal intercourse. Herpes a single will become pass on by the use of connection with one contaminated out from the computer virus. Imagine if we do not get treated so you can get Herpes a single? An integrated herpes contamination can prove to be brought about by the herpes virus (HSV), and that will come in two forms: HSV-1, there are always a usually means ones teeth herpes infection influencing either a mouth area simply to lip area; simply to HSV-2, there are always a sets off vaginal herpes influencing either a genitals simply to anus. Sadly, HSV-1 may also distribute towards the genitals during the course of ones teeth sexual intercourse, because ...
Ambiguous genitalia is when there is question about whether the child is male or female. Experienced specialists at Childrens Minnesota diagnose and treat this condition.
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S30.8 is a non-billable diagnosis code, consider using a code with a higher level of specificity for a diagnosis of other superficial injuries of abdomen, lower back, pelvis and external genitals.
ICD-9 code 016.53 for Tuberculosis of other male genital organs tubercle bacilli found (in sputum) by microscopy is a medical classification as listed
Ive been asked to comment on some of the claims made by Jessica Yaniv in their recent British Columbia Human Rights Tribunal hearing (theres some background to the case here for those not familiar with it), as well as other comments they have made in the past pertaining to being intersex.. Lets get the easy one out of the way first, Yaniv has said in the tribunal that intersex means people having both genitalia. This is a common misconception. Ive written about ambiguous genitalia and what this means before (clue: its not both), so Im not going to go into detail again here (edit: as Yaniv has made repeated claims about having intersex genitalia in both the tribunal amd media interviews, Ive written a more detailed blog about ambiguous genitalia. You can find it here). Suffice to say, if Yaniv has a penis, they do not also have a vagina. The claim I am going to explore in more detail is that Yaniv has periods. To begin with, lets remind ourselves what a period is. A period is part of ...
And how we burned in the camps later, thinking: What would things have been like if every Security operative, when he went out at night to make an arrest, had been uncertain whether he would return alive and had to say good-bye to his family? Or if, during periods of mass arrests, as for example in Leningrad, when they arrested a quarter of the entire city, people had not simply sat there in their lairs, paling with terror at every bang of the downstairs door and at every step on the staircase, but had understood they had nothing left to lose and had boldly set up in the downstairs hall an ambush of half a dozen people with axes, hammers, pokers, or whatever else was at hand? [...] We didnt love freedom enough. And even more - we had no awareness of the real situation.... We purely and simply deserved everything that happened afterward ...
May I proceed the potential viruses right to someone soon dont have any signs and symptoms? For those who have captured the tv upon all of these vegetable, you can note throughout your earliest outbreak. Sign may appear smooth whether it be genitals per se come into contact with contaminated epidermis, deficiencies in penetration does occur. That a many young adults through the U. S. To try and possess ones teeth herpes (extensive sores), which will be most of the time attributable to HSV-1. Ones teeth herpes is also some more often called vast sores and then turns up ever since sores on their lip area and then encircling regions of the facial skin. Though the its possible created for HSV-1 on to distribute to this genitals by the use of ones teeth sexual activity, additionally it really is HSV-2 this can be distribute at the time of intimate come into contact with. And then, recall, while you are not still left that an outbreak, youre likely to non-etheless deliver herpes on to your ...
According to Ravi (35), a street vendor, he was allegedly attacked at his girlfriends house in outer Delhis Mangolpuri late on Wednesday, where he was called by the womans relative.. Ravi says that, at knife point, he was forced to undress and have sex with a 23 year old woman inside a bathroom of her house and later the woman chopped off his genitals.. Here below is the story said by Ravi which was accepted by police:. Ravi was in love with a woman for four years. Over phone he was asked to come to her home by one of her relative. As he reached her home, she broached the topic of marriage. However, Ravi refused, saying his family was against it.. The victim told police that the woman then pushed him inside the bathroom, undressed him and forced him to have sex with her.. She allegedly threatened him of dire consequences if he did not give in to her demand.. Enraged at his refusal, the accused chopped off the mans genitals with a kitchen knife.. The victim said the womans brother and ...
You may have seen an odd story in the news a few weeks ago. A story about pair of women caught trying to smuggle 13 pounds of horse genitals into the country. Two immediate thoughts leapt into my head. When youve been caught smuggling 13 pounds of horse genitals, youve likely taken a few missteps down…
Embryonic appendicular structures, such as the limb buds and the developing external genitalia, are suitable models with which to… Expand ...
Scientists from the Medical School presented research results last week at the American Society for Human Genetics meeting in Baltimore. Ancient master control gene directs limb/genital development from mice to men One tiny mutation passed on for six generations in the genes of a Michigan family gave Jeff Innis the clue he needed to make a connection between evolutionary and embryological development in mice and humans. In 1996, Innis and graduate students Douglas Mortlock and Laura Post discovered that a mutation in HOXA13 was responsible for abnormal limb and genital development in mice. Because of another single-point mutation occurring over 100 years ago, he now knows that HOXA13 has the same effect in people. HOXA13 is one of 39 master control genes that regulate embryonic development in vertebrates by coordinating the activity of other genesÑturning them on and off at precise times and locations as the embryo develops. Scientists believe these ancient genes originated millions of ...
I believe that we live in a culture that oppresses women. One of the ways we are oppressed is that our bodies are politicised, censored, sexualised and controlled by others (often men). We are not supported or encouraged to talk about our bodies, especially our vulva. We are made to feel embarrassed or ashamed. When our bodies are not hidden away, when they are available for titillation, the media often only represent porn star genitals that are plucked, shaved, waxed, neat, tidy, mannequin-like and almost identikit. There is of course nothing wrong with having genitals that conform to this appearance but the prevalence of this one-size-fits-all stereotyping denies the existence of any other choices and/or presentations. As a result many women become worried that their genitals are abnormal if they dont look like what they see in the movies etc ...
Construction of reproductive organs in women is obviously different from that of the male, but still have one thing similar and even the same building, guess what the body is it? Read our article and youll know. Genitals women are especially important for reproduction. The uterus is ready for it, wear 42 weeks the fetus and then, thanks to an ingenious system of many glands and muscles to give birth. Read the main division of reproductive organs in women, you must come to things you do not know now. Function of reproductive organs in women Egg maturation and release from the ovary cortex, production of sex hormones, the realization of sexual union, if fertilization of an egg, creating a favorable environment for the development of the fetus and its birth. Efferent genital tract Fallopian tubes (tubae uterinae) - tube freely in the peritoneal algae on the pelvic wall are long about 13 cm, along with the ovaries form a so-called. Uterine appendages. The inner surface is covered with mucosa, whose cells
Are you sleeping with him?. I started coughing violently, before looking back at him, and in a high voice, demanding, - WHAT?. His eyes were intense. Are you sleeping with de Silva?. I started freaking. Uhhhhhh - . Paul blinked. Youre kidding me.. Well, I babbled, You cant technically call it SLEEPING as such, I mean, Jesses dead and all and therefore cant actually SLEEP so what we do doesnt even really involve all that much sleeping if you know what I mean, and plus it was just once and we were both drunk - how a ghost can get drunk, I dont know - and it was something that Ill never do again because WHO KNOW A GUYS GENITALS DISAPPEARED WHEN THEY DIED?. Again, Paul blinked. My genitals are still here.. Well, that was cool. Prove it.. ...
Question - Deep kissing, protected oral sex, unprotected oral sex, genitals to hands. Chances of contracting HPV ?. Ask a Doctor about diagnosis, treatment and medication for Hpv, Ask a Sexual Diseases Specialist
A few simple steps will keep your babys penis or labia clean. Our practical guide has all you need to know about care and cleaning of baby genitals.
HUMAN rights groups have condemned the Philippine president for saying troops should shoot female communist rebels in the genitals to render them…
This week is somewhat of a landmark for your developing baby. By now, your babys complete body plan is laid down. Your baby will continue to develop and grow for the remainder of the pregnancy. The fingers and toes have separated and the tail has disappeared now. Your baby has taste and tooth buds at this point, which will continue to develop. The brain will continue to grow at an amazing rate and nearly a quarter of a million new neurons are produced every minute! The embryonic heart is completely developed. External genitalia are not apparent until next week, but the testes in baby boys will already be producing testosterone. Because you have high hormone levels at this time, you may notice an abundance of emotional and physical effects. Most pregnant women find themselves getting distressed easily and have frequent mood swings. Common physical changes include the beginning of real weight gain, potential softening of the gums and slightly swollen thyroid glands. Common emotional changes ...
Amazingly Marianne and her friends are battle of the bands winners in their home town of Boston with says a lot about Boston, frankly. A lot of worrying things. Like that its perhaps not as classy as some of the films we see try to make it out to be. On the other hand, at least the place must have a sense of humour.. Eargasms contains six tracks which cover such varying topics as anally-birthed offspring, denying being gay, losing your genitals in freak gardening accidents and … well… shagging. This is most definitely not an album to put on in the car during the school run. The lyrics would make Steel Panther blush.. Musically, theyre actually pretty good. Catchy rock and rollers like FiFi make me think of the B-52s with the dual male/female vocals and the surf sound, but the band have gone for spreading their wings a bit stylewise. We have a couple of gentler numbers - Frat Guy in the Closet is mainly acoustic, and Gentleman and a Scholar wouldnt be out of place in a rock opera. ...
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Question - Irritation in the genitals after intercourse. Chances of UTI?. Ask a Doctor about diagnosis, treatment and medication for Urinary tract infection, Ask a Urologist
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A tiny water-dwelling insect has the loudest song for its size in the world, researchers find - a mating call it probably makes with its genitals.
Helpful, trusted answers from doctors: Dr. Childs on change in color of genitals: If you have liver damage or certain types of cancer, kidney failure, anemia, and other medical conditions you can have changes in your color tones. Hormone medication as well as pregnancy can cause melasma and some prescriptions can also give those side effects. Speak with your doctor about your medical condition, medication list, or diet (too many carrots) and see if you can get help with this.
According to this report ( Sept.13,2010) over $800,000 in U.S. taxpayer dollars (adding to U.S. indebtedness to China) will go to teaching African males how to wash their genitalia. Some taxpayers may wonder how the rest of the $12 million will be spent. Quote: The National Institute of Mental Health (NIMH), a division of the National…
Looking at and talking about genitalia: understanding where physicians and patients get their ideas about whats normal and what isnt ...
A netizen reported a man stripping naked when the train he was on nears its arrival at Yishun MRT station. The male commuter in question suddenly threw his bag down and started playing with his genitals, according to eye-witnesses, before deciding to lie on the floor. ...
A 40-year old man, who was arrested in Portland on Monday for allegedly washing his genitals in a park drinking fountain while kids played close by, said he was just trying to take a quick bath, according...
has been moved to new address. Rep. Anthony Weiners Fall From Grace Continues With Purported Photograph of Fully Exposed Genitals Sorry for inconvenience... Redirection provided by Blogger to WordPress Migration Service ...
SAN ANTONIO, Tx. - A 34-year-old woman will spend the next two years in federal prison after she pleaded guilty to tearing her young sons genitals and then using glue to try and fix the wound. Jennifer Vargas pleaded guilty to the crime.
Ive had several posts the last week or so with vibrating, buzzing, and goosebumps sensations. Today, I am having a burning, numbness, vibrating in my genitalia area. This I have never had before. ...
An alleged escort was arrested and charged with attempted murder for biting a mans genitals in an Orange County hotel room, deputies said.
genitalia as art? - MISCELLANEOUS TOPICS - I am just wondering if anyone else is as mystified by things like a crocheted vulva or crotch embroidery as I am. I just dont
Days after his junk made news after a scandalous leak of nude photos, Justin Biebers genitalia is back in the headlines - this time with a lawsuit.
Ringtones of Show Me Your Genitals by John Lajoie. Make your own custom ringtones of popular songs! Choose from popular starting times then upload one of your downloaded MP3 files to create any custom ringtone of any song.
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Secondary stage: A non-itchy rash can develop anywhere from 14 to 90 days after sexual contact. The rash can appear anywhere on the body, but it is most often found on the chest, belly, genitals, palms of the hands and soles of the feet. The rash usually disappears, but it can come back months later. Other symptoms may include headache, fever, hair loss, swollen lymph nodes and bumps or patches inside the mouth, anus, penis/external genitals, or vagina/internal genitals ...
You mean, the way I would look stupid if I walked around with a gigantic dick on top of my head? Kind of bobbin and boingin around, like a hot dog in a hurricane. Yeah, Im not sure stupid is the right word, but I have never understood the thinking behind pussy hats. I always wonder what the rest of the World thinks when they see photos of thousands of American women wearing replicas of their external genitalia on their heads in public. It must really worry them, that we have those nukes. Plus, they have to wonder if American womens external genitalia really look like that. ...
A study finds male genitalia are shrinking because of environmental factors. Limbaugh says it has to be the feminazis and chickification.
A study finds male genitalia are shrinking because of environmental factors. Limbaugh says it has to be the feminazis and chickification.
Looking for online definition of organa genitalia in the Medical Dictionary? organa genitalia explanation free. What is organa genitalia? Meaning of organa genitalia medical term. What does organa genitalia mean?
66 sentence examples: 1. They are found on the external genitalia and on the thighs, buttocks, and lower abdomen. 2. Until recently, the position of female genitalia on the homunculus had only been guessed at. 3. Instead, it means female genitalia in
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Several years ago I was sitting in a Pei Wei with my then girlfriend, Joyce, when she looked up from her General Tsos chicken and said, You left the toilet seat up again last night.. Thinking she meant this only as an observation, I decided to respond with a little bit of improvised theory on the matter.. You know, I said, I think it should be the other way around: Women should have to put the seat down for themselves, then put it back up when theyre done. The reason being: Women dont have to touch their genitals when peeing, and men do. Therefore, to keep us from transferring bacteria and other problematic microbes from the toilet seat to our, I lowered my head and gestured at my food.. Asian fusion? she said.. No. What? Noodles.. Joyce nodded. Oh.. And therefore, I continued. It would be helpful if we didnt have to touch the seat before urinating.. Chewing her food, she remained silent for a second before taking a sip of water, then wiping her mouth.. I wouldnt make a ...
The young man that is originally from El Salvador and is an active member of the MS-13 crime family is believed to have attempted to gold plate his own genitals with a professional automotive gold plater stolen from a local garage after first painting his genitals with a lead-based paint, believe experts.. The 17-year old man who was allegedly a fan of the 2002 American comedy movie Goldmember, which is a loose parody of the James Bond films Goldfinger, had taken the Spanish nickname of Pelotas de oro, or golden testicles, before attempting to gold plate his own genitals to his ultimate demise.. ...
The young man that is originally from El Salvador and is an active member of the MS-13 crime family is believed to have attempted to gold plate his own genitals with a professional automotive gold plater stolen from a local garage after first painting his genitals with a lead-based paint, believe experts.. The 17-year old man who was allegedly a fan of the 2002 American comedy movie Goldmember, which is a loose parody of the James Bond films Goldfinger, had taken the Spanish nickname of Pelotas de oro, or golden testicles, before attempting to gold plate his own genitals to his ultimate demise.. ...
reproductive system or genital system is a system of organs within an organism which work together for the purpose of reproduction. Many non-living substances such as fluids, hormones, and pheromones are also important accessories to the reproductive system. The major organs of the human reproductive system include the external genitalia (penis and vulva) as well as a number of internal organs including the gamete producing gonads (testicles and ovaries). Diseases of the human reproductive system are very common and widespread, particularly communicable sexually transmitted diseases.Medical Tests Analyzer labtest bloodtest What does the test result mean?
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Learn more about Ambiguous Genitalia symptoms, diagnosis, and treatments from experts at Boston Childrens, ranked best Childrens Hospital by US News.
Learn about Ambiguous Genitalia symptoms and causes from experts at Boston Childrens, ranked best Childrens Hospital by US News.
A group of externally very similar, grey species of the genus Nemophora Hoffmannsegg, whose females possess a brush of dark scales at the middle of their antenna, is revised. Five species of this group, all distributed in South-East Asia, are recognized: N. griseella (Walsingham) sp. rev. [= cyphozona (Meyrick) syn. n. ; = tricrates (Meyrick) syn. n.] from India, Burma and Nepal; N. ichnodesma (Meyrick) comb. n. from India and W Malaysia; N. cassiterites (Meyrick) comb. n. from India only; N. askoldella (Millière) [= irroratella (Christoph) ; = niphites (Meyrick) syn. n.] from China, S Korea, Japan, Khabarovsk and Primorye regions of Russia; N. chionites (Meyrick) comb. n. from India and Thailand. Data on all primary types are provided; lectotypes are designated where necessary. The monophyly of the group and the relationships of its species are discussed. Keys to species based on external characters and male genitalia are provided; adults and male genitalia are described and illustrated.
The sexual transmission of viruses is responsible for the spread of multiple infectious diseases. Although the human immunodeficiency virus (HIV)/AIDS pandemic remains fueled by sexual contacts with infected semen, the origin of virus in semen is still unknown. In a substantial number of HIV-infected men, viral strains present in semen differ from the ones in blood, suggesting that HIV is locally produced within the genital tract. Such local production may be responsible for the persistence of HIV in semen despite effective antiretroviral therapy. In this study, we used single-genome amplification, amplicon sequencing ( gene), and phylogenetic analyses to compare the genetic structures of simian immunodeficiency virus (SIV) populations across all the male genital organs and blood in intravenously inoculated cynomolgus macaques in the chronic stage of infection. Examination of the virus populations present in the male genital tissues of the macaques revealed compartmentalized SIV populations in testis,
N51* - Disorders of testis and epididymis in diseases classified elsewhere; Balanitis in diseases classified elsewhere; Other disorders of male genital organs in diseases classified elsewhere: Diseases and Medical Conditions (ICD-10) from
CAIX expression in bronchial trees and genital organs: In the bronchial trees high expression of CAIX was seen in the peribronchial immature mesenchymal cells a
See? Its so not just you.. Not feeling anything at all, or feeling very little, with any kind of genital sex where the most sensory parts of the genitals are being stimulated is most typically an indication someone is just not very aroused or as aroused as they need to be. We dont all need to be turned on to the same degree to have various kinds of sex feel pleasurable, but sometimes or for some people more than others, being as amped up as possible is key. And when we are fully aroused, every kind of sex is always going to feel more intense.. Parts of our genitals are incredibly sensitive, but how sensitive they are has a LOT to do with if were highly sexually excited or not, which is why when we, say, wipe after toileting, wash ourselves in the bath, or have a pelvic exam, were not usually in the throes of ecstasy. Most of arousal, and all of sexual response, and most of pleasure is about our brains and central nervous systems. If theres not a whole lot of the good stuff going on upstairs ...
Intersexed people tend to have ambiguous genitalia, rather than both.. What the biology means - is that most boys look like boys, emote like boys, smell and hear like boys, have XY chromosomes, have male genitalia etc. And most girls look like girls etc etc.. But some children behave as neither, no matter what they look like. Some boys have ambiguous genitalia, or even look female. Some girls have masculinised bodies. Mostly they dont. Mostly, everything matches. Mostly. But sometimes it doesnt, and this isnt because theyre evil or perverted or attention-seeking or any of the other vices ascribed to them, its because of their physical anatomy.. 1 in 300 men dont have the XY chromosomes most men do. 1 in 650 girls dont have XX chromosomes either. About 1 in 200 children have had some surgical reconstruction of their genitalia, sometimes the wrong way. 1 in 3000 are Transsexual, anatomically male brain in otherwise anatomically female body, or the reverse.. Add up all the various forms of ...
In an effort to ground the rise of FGCS in a longer history of (mostly Western) medical ideas regarding what are considered normal genitals, Nurka largely focuses on one of the surgeries that falls under this grouping, labiaplasty (the removal or reduction of protruding labia). As often the need for and use of labiaplasty is based on perceptions (from both clinicians as well as women) that labia are larger or more pronounced than is typical, she asks: where did the diagnosis of labial hypertrophy come from?1 Nurka seeks answers in a series of chapters that each focus on a different era, starting with Hippocratic medicine, then turning to early Roman physicians through Vesalius to the seventeenth century, before moving to the nineteenth century and Western European colonial interest in Indigenous Khoi womens genitalia. She then spends a chapter considering the work of the early twentieth-century French clinician Félix Jayle, who she believes to be the first medical author to attempt to ...
We obtained 191 Cholevini specimens belonging to 33 species. Specimens were collected in Europe, Japan and North America (electronic supplementary material, S2) and preserved in pure ethanol in the field. Additionally, we obtained published sequences from Fresneda et al. [17] and Schilthuizen et al. [18], and from GenBank, making a total of 212 individuals belonging to 40 nominal species. For the outgroup, we used one species each of four other Cholevinae tribes, namely Graciliella apfelbecki (Leptodirini), Ptomaphagus subvillosus (Ptomaphagini), Speonemadus maroccanus (Anemadini) and Sciaphyes sibiricus (Sciaphyini). The data for the former two species were generated in the present study, while those for the latter two were taken from Fresneda et al. [17]. From each specimen, we dissected the genitalia and removed three legs from one flank. The legs and sometimes also abdominal tissue were used for DNA extraction, whereas the body and the genitalia were mounted dry, pinned, labelled and stored ...
London - Michael Phelpss girlfriend has revealed she was born with male genitalia. Taylor Lianne Chandler, who started dating the Olympic swimmer in August after they met through the dating app Tinder, announced on her Facebook page that she was an intersex baby and named David Roy Fitch by her parents. She wrote: I was…
True underdevelopment of male genitalia is a rare conditionSunbury Daily ItemANSWER: I hear this question frequently, and most of the time when I perform an
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Male Genitalia and Prostate Exam CPD Lab Student examiner: Patient name: Tim Xyz. Age: 52. Date of exam: 4/25/09 S: No history of hernias, urinary or sexual malfunction. O: On observation the patient has no bulges or scars in the inguinal region, and reports no history of hernias. Three sclerotic…
Male genitalia of Varicopsella species: pygofer lobe, aedeagus and dorsal connective, lateral view. (16) Varicopsella (Varicopsella) breakeyi; (17) V. (V.) eleg
Dr. Bensinger responded: Old wives excuse. Spermatozoa are designed to survive in very special environment. A toilet seat is not that environment. Even if the women in question deliberately tried to introduce some of the |a href=/topics/semen track_data={
A man in Uganda recently contracted the Ebola virus after stealing a cellphone; that is no surprise considering a report that said that the average cellphone carries ten times the amount of bacteria as a toilet seat...
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Womens health Aortic Aneurysm question and answers about Bent down to pick up toilet seat and got throbbing pain in lower back hurting still constant then gets really hurting all of a sudden hurts in abdomen like little pulses too
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American author Christopher Bollen was named winner of the 2017 prize for bad sex in fiction on Thursday, for a passage from his novel The Destroyers, which sees the male protagonist comparing his own genitalia to a billiard rack.
Chimerism is defined as the presence in a subject of more than one stable and genetically distinct cell line; cases reported so far include both patients with ambiguous genitalia and healthy subjects. The biological mechanisms, which may give origin to chimeras, are complex, and can be understood by analyzing DNA samples of the patients and their parents using molecular techniques. The objective of this study is to identify the mechanism of origin for the 2 cases we report. The first patient is a phenotipically normal girl with normal (external and internal) genitalia; the second patient had ambiguous genitalia and underwent surgery. DNA was purified from blood samples and, limited to Patient 1, from a sample of biliary cyst. Short tandem repeat polymorphisms were analyzed in order to identify the relative parental contribution to the patients. Molecular analyses carried out on the first patient are not fully informative because of two possible explanations (|i|i.e. |/i|parthenogenetic and andrognetic
Male genitalia[edit]. See also: Penis § Felidae. In the male cat, the genitalia includes the penis, which is covered with small ... Female genitalia[edit]. In the female cat, the genitalia include two gonads, the uterus, the vagina, the genital passages and ...
6 External genitalia *6.1 Common development *6.1.1 Before differentiation * Urogenital membrane ... Until about the ninth week of gestational age[4] the external genitalia of males and females look the same, and follow a common ... Development of external genitalia. A: common development. C, E: male development. B, D, F: female development ...
Genitalia. Penis are standard gonyleptoid and very conservative, with rectangular ventral plate, puffed sac-glans, well- ...
A small number of affected people have external genitalia that do not look clearly male or clearly female (ambiguous genitalia ... In some cases, gonadal surgery can be performed to remove partial or whole female genitalia. This may be followed by plastic ... The appearance of XX males can fall into one of three categories: 1) males that have normal internal and external genitalia, 2 ... Individuals with SRY-negative 46,XX testicular disorder of sex development are more likely to have ambiguous genitalia than are ...
Male genitalia. Uncus moderately long, stout, with a broad, rounded tip; beyond the uncus a weak structure of hair-like setae; ... Also, the female genitalia can be recognized quite well. In particular, the degree of sclerotization of sternite IX and of the ... Female genitalia. Tergite IX missing, only indicated by a group of setae; sternite IX strongly reduced, weakly sclerotized, ... Phylogeny: In the male genitalia, M. aglaella has distinct lobes with long, hair-like setae on the posterior margin of the ...
... burning genitalia; forcing objects into the rectum; beatings while the victim is suspended from the ceiling and on the soles of ...
Genitalia large. Yellow spots reach the side margin of tergites 3 and 4.Scutellum mainly yellow-haired. Female frons with white ... The male genitalia and the larva are figured described by Dusek & Laska (1961) Habitat: grassland, dune systems, dry river beds ...
... burning genitalia; beating, sometimes while the victim was suspended from the ceiling; dousing victims with freezing water and ...
Volume IV The spleen; the liver and gall bladder; the kidneys and the bladder; the genitalia; pregnancy; the muscles. The ...
Osman Hill, W. C. (1958). "External genitalia". In Hofer, H.; Schultz, A. H.; Starck, D. (eds.). Primatologia. 3. Basel: Karger ...
Genitals. A newborn's genitals are enlarged and reddened, with male infants having an unusually large scrotum. The breasts may ...
The male genitalia contain some of the most distinguishing characteristics when differentiating bumble bee species. The ... "Psithyrus male genitalia". Bumblebee ID. Retrieved 25 April 2019. Sramkova, A.; Ayasse, M. (2009). "Chemical ecology involved ...
... genitalia concealed by skin (unknown gender, unless skin removed) Aylonit: Barren female. Female genitalia, barren. Saris: ... Intersex people are born with sex characteristics, such as chromosomes, gonads, or genitals that, according to the UN Office of ... In old Israel there were: Zachar: male Nekeva: female Androgynos: both male and female genitalia (eternal doubt of legal gender ... Joyce notes that many figures of mesoamerican art are depicted with male genitalia and female breasts, while she suggests that ...
The genitalia differ. Adults are on wing from April to May in western Europe. The larvae feed on Populus x canadensis and ...
As long as the skin covers their genitals, they are considered doubtful men and women. As long as the skin is present, they are ... It usually refers to a person whose sex is unknown because their genitalia are covered or "hidden" or otherwise unrecognizable ... "Ambiguous genitalia (tumtum)." Encyclopedia of Jewish Medical Ethics. Jerusalem, Israel: Feldheim Publishers, 2003. Page 50-53 ... symbolize their genitals being uncovered and remade. The eleventh century dictionary, the Aruch, says the word tumtum came from ...
Genitals[edit]. Infection of the vagina or vulva may cause severe itching, burning, soreness, irritation, and a whitish or ... and the genitalia (vagina, penis, etc.);[23][24][25] less commonly in healthy individuals, the gastrointestinal tract,[26][27][ ... Symptoms of infection of the male genitalia (balanitis thrush) include red skin around the head of the penis, swelling, ...
Genitals[edit]. The genital tubercle is a small bump that eventually develops into a penis or a clitoris on a human fetus. ...
A09: Genital systems (systemata genitalia)[edit]. *Female internal genitalia. *Female external genitalia ...
Jesus with erased genitalia; Jesus minus erotic body." Instead, she speaks about the bi-sexuality of Christ as an inclusive ...
The male external genitalia consist of the penis, the male urethra, and the scrotum, while the male internal genitalia consist ... ISBN 978-0-7167-5706-1. "Definition of Male genitalia". MedicineNet. "Why is life expectancy longer for women than it is for ... The male reproductive system includes external and internal genitalia. ...
ISBN 0-7817-5309-0. "Chapter 35: Female genitalia". Retrieved 2007-12-09. Anatomy photo:43:03-0300 at the SUNY Downstate ...
All have similar genitalia. The pattern is black with white marks above and with brick-red areas beneath. In G. endochus the ...
Lost, Cosmos The In (2014-09-04). "Nudus Nudum Christum Sequi: On Christ's Genitalia". Cosmos The In Lost. Retrieved 2019-06-15 ... his genitalia). The phrase originated from Saint Jerome who wrote in four letters to embrace a life in the mold of Jesus of ... produced a large body of devotional images in which the genitalia of the Christ Child, or of the dead Christ, receive such ... of Christ in Renaissance Art and in Modern Oblivion as a blunt overlook of how many depictions of Jesus and his genitalia are " ...
Male genitalia Beccaloni, G.; Scoble, M.; Kitching, I.; Simonsen, T.; Robinson, G.; Pitkin, B.; Hine, A.; Lyal, C., eds. (2003 ...
Kellaway, Kate (April 22, 2001). "Talking 'bout our genitalia". The Guardian. Retrieved October 7, 2015. Llewellyn Smith, Julia ...
... hypoplastic genitalia: underdeveloped genitalia undescended testis (males) micropenis (males) small testis (males) Note: it is ... "Hypoplastic male external genitalia". National Center for Biotechnology Information. U.S. National Library of Medicine. ...
Female Genitalia System: f. History of major abnormalities or defects of the genitalia, such as hermaphroditism, ... Male Genitalia System: m. History of major abnormalities or defects of the genitalia such as hermaphroditism, ... and 15r", here it was listed as "major abnormalit[y] or defect of genitalia". The amendments made for transgender people were ... gender identity disorder to include major abnormalities or defects of the genitalia such as change of sex or a current attempt ...
Male Genitalia), subparagraph l.: History of major abnormalities or defects of the genitalia such as change of sex (P64.5) (CPT ... Female Genitalia), subparagraph e.: History of major abnormalities or defects of the genitalia such as change of sex (P64.5) ( ... Male Genitalia: History of major abnormalities or defects of the genitalia such as hermaphroditism, pseudohermaphroditism, or ... People born with non-standard genital anatomy or ambiguous genitalia are largely excluded from military service. This practice ...
Pierce & Metcalfe, 1922 (Archipsidii). Genitalia Group Tortricidae Lepid. Br. Is.: XXI, 1. Dugdale, J.S. 1990: Reassessment of ...
Genitalia are not present. Concerning ManuelbastionLAB, the word phenotype is intended with the following meaning: A "phenotype ...
From Latin genitalia, substantive use of plural of genitalis ("pertaining to generation or birth"). ... genitalia in Charles du Fresne du Canges Glossarium Mediæ et Infimæ Latinitatis (augmented edition, 1883-1887) ... Retrieved from "" ... genitalia n pl (definite plural genitaliaa) *genitalia Synonym: kjønnsorgan. References[edit]. *"genitalia" in The Nynorsk ...
... Male genitalia The male genital organs comprise the testes and epididymides, ductus deferentes, ...
The uniqueness of genitalia of a species led to the use of the morphological study of genitalia as one of the most important ... Genitalia in male and female of any particular Lepidopteran species are adapted to fit each other like a lock (female) and key ... The genitalia are attached onto the tenth or most distal segment of the abdomen. Lepidoptera have some of the most complex ... The genitalia are complex and provide the basis for species discrimination in most families and also in family identification. ...
Ambiguous genitalia is a birth defect where the outer genitals do not have the typical appearance of either a boy or a girl. ... Ambiguous genitalia is a birth defect where the outer genitals do not have the typical appearance of either a boy or a girl. ... Causes for ambiguous genitalia includes:. *Pseudohermaphroditism. The genitalia are of one sex, but some physical ... This is because it is easier for a surgeon to make female genitalia than it is to make male genitalia. Therefore, sometimes ...
Media in category "Labia (genitalia)". The following 51 files are in this category, out of 51 total. ... part of the female genitalia (en); جزء من العضو التناسلي عند إناث البشر (ar); Osa naisen ulkoisia sukupuolielimiä (fi) genital ... Retrieved from "" ...
Did you know ducks have probably the most interesting genitals of all bird species? The evolution of the enormous duck phallus ... Duck Genitalia Tells an Evolutionary Tale. Did you know ducks have probably the most interesting genitals of all bird species? ... Did you know ducks have probably the most interesting genitals of all bird species? The evolution of the enormous duck phallus ... In the fall, the genitalia will disappear, only to reappear next spring. ...
The restaurant is sexist though as it doesnt serve female genitalia - but oh what the heck. ...
... and we were talking about something in the news that had to do with male genitals. ... That being said,in mixed company,Ill use "Twig and Berries" for male genitalia and "HooHa" for female genitalia. Never fails ... How Women Own, Name & become Comfortable with their Genitals. *If you want to know what women have been up to, look at mens ... Men are a little ahead of the game here as male sexuality, desire, and even their genitals are more external in nature. Many ...
... Related: female genitalia - male genitalia - private - pubic hair - pudenda Definition. A sex organ or primary ... [May 2004] Intimate and private parts. An intimate or private part is a place on the ...
Ambiguity of a newborns genitalia or clinical situations in which determining the sex of a newborn is not clear represent a ... Ambiguous genitalia Sex determination Sex differentiation Adrenal hyperplasia Gonadal dysgenesis This is a preview of ... Ambiguous genitalia are due to under-masculinization of genetic males or virilization of genetic females. Although congenital ... Ambiguity of a newborns genitalia or clinical situations in which determining the sex of a newborn is not clear represent a ...
... is a condition that affects the development of the brain and genitalia. Explore symptoms, inheritance, genetics of this ... X-linked lissencephaly with abnormal genitalia (XLAG) is a condition that affects the development of the brain and genitalia. ... or external genitalia that do not look clearly male or clearly female (ambiguous genitalia). ... Another key feature of XLAG in males is abnormal genitalia that can include an unusually small penis (micropenis), undescended ...
Genitalia as Social Constructs - By besieging, indicting and belittling traditional masculinity, Americas rulers aim to ... Genitalia as Social Constructs. By Linh Dinh (Page 1 of 2 pages) (View How Many People Read This) No comments ...
Mutilated Genitals is a promotional EP by Dog Fashion Disco released in 2001. It has since been deleted and is quite rare, but ... ... ", "Dont fall asleep or well mutilate your genitals". The versions of tracks 4 and 5 are re-recordings; they would appear on ...
... by keeping certain kinds of genitals in one bathroom and other kinds of genitals in another-even though theres no evidence to ... this obsession with transgender genitalia would be laughably absurd. After all, who really cares what genitals someone else has ... And on a cultural level, its no surprise that with the bizarre level of significance we ascribe to our genitalia-from gender ... Indeed, many of the same cisgender people who bristle at having their genitalia scanned in airport security lines seem to think ...
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Chicken wings cause smaller genitalia? Posted By -NO AUTHOR-. On 09/03/2013 @ 2:39 pm In Diversions,Health , No Comments ( ... URL to article: ...
All about Sarcoma of the female genitalia by (Gynecologist) Guenter Koehler. LibraryThing is a cataloging and social networking ... Sarcoma of the female genitalia. by (Gynecologist) Guenter Koehler. Members. Reviews. Popularity. Average rating. Conversations ...
A male fish from Mexico has some fearsome genitalia. Equipped with four hooks, the males sex parts might allow him to grab ... Mosquitofish sports fearsome genitalia. The hooked male genitalia of mosquitofish is seen as an evolutionary response to ... The four-hooked genitalia could help the males overcome resistance and latch onto a females genital pore and deposit sperm ... A male fish from Mexico has some fearsome genitalia. Equipped with four hooks, the males sex parts might allow him to grab ...
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An Indian woman defended herself from an alleged attacker by cutting off his genitals. Credit: AFP ...
... what is the purpose of the Genitalia exam? I was reading from several sources, but the only thing I could find was the ... With a school physical / sports physical on children, what is the purpose of the Genitalia exam? I was reading from several ... Is this the only important of the Genitalia exam in school / sports physicals? What about females? Also, how many practitioners ...
Learn about the anatomy and physiology of genitals and genitalia in both males and females. ... What are the definitions of genitals and genitalia terms? ... Genitals (or genitalia) are the sex organs in the pelvic region ... Male and female genitals are divided into external genitals (those visible outside the body) and internal genitals (those that ... The males external genitals include the penis and the scrotum. The internal genitals include the testicles, or testes, ...
... which sees the male protagonist comparing his own genitalia to a billiard rack. ... which sees the male protagonist comparing his own genitalia to a "billiard rack." ...
Earliest wall art features female genitalia. Tuesday, 15 May 2012 AFP. A close up of a carved image of a vulva from the rock ... Use these social-bookmarking links to share Earliest wall art features female genitalia. ... Use this form to email Earliest wall art features female genitalia to someone you know:. ...
A study finds male genitalia are shrinking because of environmental factors. Limbaugh says it has to be the feminazis and ... Rush Limbaugh: Male Genitalia Are Shrinking Because Of Feminazis A study finds male genitalia are shrinking because of ... In a study looking at changes in male genitalia over the past 50 years, Italian researchers found that penises were around 10 ...
When to Worry About Your Newborns Genitals Your newborn girls genitals have been exposed to many hormones in the uterus. ... Caring for Your Baby Girls Genitals. Clean your daughters genitals as you would any other part of her body. Spread the labia ... Your Newborn Girls Genitals and Bleeding. In this Article. In this Article In this Article * Caring for Your Baby Girls ... When to Worry About Your Newborns Genitals. Contact your pediatric provider if you smell a foul odor from the discharge, which ...
See an archive of all other uses for your genitals stories published on the New York Media network, which includes NYMag, The ... Other Uses For Your Genitals. Most Recent Articles. @media (min-width: 0px) and (max-width: 599.9px) { .search-results-bg-1 { ...
... known as SGLT2 inhibitors are linked with an increased risk of developing a flesh-eating bacteria that attacks the genitals, a ... It gets worse rapidly and is found on the external genitals and the area around the anus. It is an emergency. Symptoms may ... Those can include trauma after sex, a urinary tract infection, piercing of the genitals, getting a prosthetic penile implant, ...
I have developed a red bump on my inner thigh area close to my genitals. It looks similar to a skin tag however it is red in ... Skin tag on genitals? kayleeD I have developed a red bump on my inner thigh area close to my genitals. It looks similar to a ... Skin tag on genitals?. I have developed a red bump on my inner thigh area close to my genitals. It looks similar to a skin tag ...
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  • Ambiguous genitalia is a birth defect where the outer genitals do not have the typical appearance of either a boy or a girl. (
  • Ambiguous genitalia can develop if the process that causes this fetal tissue to become "male" or "female" is disrupted. (
  • Undescended testicles commonly occur with ambiguous genitalia. (
  • With a few exceptions, ambiguous genitalia is most often not life-threatening. (
  • Ambiguous genitalia are due to under-masculinization of genetic males or virilization of genetic females. (
  • Although congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is the most common cause of ambiguous genitalia in a newborn, other causes should be considered after ruling out this inherited adrenal condition. (
  • Another key feature of XLAG in males is abnormal genitalia that can include an unusually small penis (micropenis), undescended testes (cryptorchidism), or external genitalia that do not look clearly male or clearly female (ambiguous genitalia). (
  • Ambiguous genitalia is a rare condition. (
  • Ambiguous genitalia is often a sign of one of several conditions categorized as a disorder of sex development - often referred to as a DSD. (
  • Who gets ambiguous genitalia? (
  • If there's a family history of ambiguous genitalia, a baby may be at higher risk of inheriting it. (
  • Ambiguous genitalia or DSD happens in about one in 1,500 births. (
  • Both and girls can be affected by ambiguous genitalia. (
  • What causes ambiguous genitalia? (
  • The development of ambiguous genitalia can be caused by abnormalities in the chromosomes, in the development of ovaries or testes, or in hormone production. (
  • Other cases of ambiguous genitalia happen after the genetic sex - XX or XY - is determined. (
  • Ambiguous genitalia can also develop through other disruptions in fetal development of the sex organs. (
  • What are the symptoms of ambiguous genitalia? (
  • Because there are different types of ambiguous genitalia, there are also different symptoms. (
  • Females with ambiguous genitalia may have an enlarged clitoris, labia that are fused or convergence between the urethra and vagina. (
  • Ambiguous genitalia is usually not life-threatening unless a child has congenital adrenal hyperplasia (CAH). (
  • What conditions involve ambiguous genitalia? (
  • How is ambiguous genitalia diagnosed? (
  • Ambiguous genitalia is often diagnosed at birth or shortly after. (
  • Doctors and nurses who help with the delivery may notice signs of ambiguous genitalia in the baby. (
  • Discovering that your newborn has ambiguous genitalia can be emotionally traumatizing and confusing for you and your family. (
  • Ambiguous genitalia are sexual organs that aren't well formed or aren't clearly male or female. (
  • An estimated 1 in 4,500 infants are born with ambiguous genitalia. (
  • With few exceptions, babies with ambiguous genitalia are physically healthy. (
  • Ambiguous genitalia can signal a medical emergency if the condition is the result of a rare form of a genetic disorder called congenital adrenal hyperplasia. (
  • What is ambiguous genitalia? (
  • The Clinic is designed to address psychosocial issues that may arise from ambiguous genitalia. (
  • The goal was to refashion M.C.'s "ambiguous" genitals to look feminine, in order to match the child's female gender assignment. (
  • When a child's gender is in question at birth, because genitals may not appear clearly male or female, the child is said to have ambiguous genitalia. (
  • Ambiguous genitalia can be a traumatizing experience for parents. (
  • A variety of genetic and environmental factors may influence this development, leading to ambiguous genitalia. (
  • Ambiguous genitalia, as the word implies, may make determining the child's gender more difficult. (
  • Very few infants with ambiguous genitalia have genitals that are so ambiguous that a gender determination is not made at birth. (
  • There are a number of different causes of ambiguous genitalia, with the most common described below. (
  • External genitalia that are partially ambiguous. (
  • Testes with ambiguous genitalia. (
  • When a child's genitalia appear ambiguous at birth, your child's physician will conduct a medical history and a physical examination of your child's external genitalia. (
  • Treatment for ambiguous genitalia depends on the type of condition and may include diagnostic or reconstructive surgery. (
  • Diagnosing a newborn with a disorder of sex development (DSD) or ambiguous genitalia should be treated with urgency and the neonatologist on call should be informed. (
  • Included are development of ambiguous genitalia, congenital disjunction of internal and external sex anatomy, incomplete development of sex anatomy, sex chromosome anomalies and disorders of gonadal development (1) . (
  • ambiguous genitalia or other gender disorders. (
  • Ambiguous genitalia is a rare condition in which an infant's external genitals don't appear to be clearly either male or female. (
  • In a baby with ambiguous genitalia, the genitals may not be well-formed or the baby may have characteristics of both sexes. (
  • The external sex organs may not match the internal sex organs or genetic sex.Ambiguous genitalia isn't a disease. (
  • More information about ambiguous genitalia, including causes and treatment, can be found at the above referred-to link. (
  • There are many options for corrective treatment for a child born with ambiguous genitalia, all that is needed is the right family that is able to care for the child. (
  • Some wanted to comment or ask questions but many contacted us directly or indirectly [e.g. 5 ] asking for specific guidelines on how to manage cases of traumatized or ambiguous genitalia. (
  • In all cases of ambiguous genitalia, to establish most probable cause, do a complete history and physical. (
  • Disorders of sex development (DSD) are congenital conditions where there is an inconsistency between chromosomal, gonadal, and/or anatomic sex and includes individuals with ambiguous genitalia, the situation in which the genital appearance does not permit an accurate declaration of gender. (
  • Ambiguous genitalia, one presentation of DSD, involves external genitalia that are neither fully differentiated as male or female. (
  • Ambiguous genitalia include a spectrum ranging from mildly virilized female genitalia with clitoromegaly and/or posterior labial fusion to essentially male genitalia with hypospadias and a unilateral gonad. (
  • Newborns may present with ambiguous genitalia, which may not permit a sex assignment at birth. (
  • Because outcome-based guidelines are lacking and the ideal management for any infant with ambiguous genitalia is unknown, decisions made by a multidisciplinary team are highly recommended. (
  • Numerous published studies by an EPA scientist found that rats fed vinclozolin in utero had feminized genitalia with malformations like vaginal pouches, undescended testicles, and malformed penises. (
  • For such taxa, the pattern of genital asymmetry evolution appears to be a component of the more general phenomenon of rapid and divergent evolution in male genitalia [ 10 ], explained as the result of two not entirely mutually exclusive classes of sexual selection, namely cryptic female choice and sexually antagonistic co-evolution [ 7 ]. (
  • In contrast to male genitalia that typically exhibit patterns of rapid and divergent evolution among internally fertilizing animals, female genitalia have been less well studied and are generally thought to evolve slowly among closely-related species. (
  • The aim of this study rests on three premises: (i) Humans are altering ecosystems worldwide, (ii) environmental variation often influences the strength and nature of sexual selection, and (iii) sexual selection is largely responsible for rapid and divergent evolution of male genitalia. (
  • The male and female reproductive organs and genitals both come from the same tissue in the fetus. (
  • Genitals (or genitalia) are the sex organs in the pelvic region of both men and women. (
  • As a result, the person's genitals are typically female in appearance, but the person does not have internal sex organs. (
  • Pure gonadal dysgenesis - a female child who has a 46, XY karyotype, underdeveloped gonads, internal female reproductive organs and female external genitalia. (
  • Pseudohermaphroditism - children who have questionable external genitalia, but have only one gender's internal reproductive organs. (
  • Females with penislike genitals and males with vaginalike organs are cases of a new extreme reversal of sex roles researchers have discovered in little-known cave insects. (
  • Genitalia is defined as the sex organs , or any anatomical parts , which are involved in sexual reproduction , and constitute the reproductive system in a complex organism. (
  • The bill focuses on intersex minors, defined as someone who is born with atypical physical sex characteristics, which could include genitals or internal organs that don't conform to a single gender. (
  • In women, after 40 years the cause of itching genitals must first seek internal organs and various chronic diseases in the pathology (eg, diabetes mellitus). (
  • Normal female external genitalia. (
  • The four-hooked genitalia could help the males overcome resistance and latch onto a female's genital pore and deposit sperm inside her. (
  • As with males, the female genitals are partly external and partly internal. (
  • Males typically have normal-appearing genitals. (
  • But to say that gives you "both sets of genitals" is to pretend that somehow all that matters to males is their penises and all that matters to females in their vaginas. (
  • The distance between the anus and the genitals is typically 50 to 100 percent longer in males than in females, and a shortened anogenital distance may signal incomplete masculinization, the researchers said. (
  • In the context of male genital asymmetry, evolution under cryptic female choice would mean that, under some conditions, females prefer males with asymmetric genitalia-perhaps because decoupling of left and right sides of the genitalia allows a more varied mix of tactile signals. (
  • The external genitals start out as several small bulges that form between your baby's legs at 6 weeks of pregnancy. (
  • Whether it's Germaine Greer declaring , "just because you lop off your penis… it doesn't make you a woman," or U.S. Republican state representatives trying to pass laws restricting bathroom usage by " original birth certificate " (i.e., the genitals you were born with), transphobia is often fueled by a fixation on the contents of people's pants. (
  • The male's external genitals include the penis and the scrotum. (
  • In terms of sexual play and sexual intercourse, the single most important part of a man's genitals is undoubtedly his penis. (
  • What people mean when they say a person "was born with both sets of genitals" is that a child may be born with a phallus that looks a lot like a penis plus a vagina (the tubular organ that goes from the outside of the body towards the uterus, if there is a uterus). (
  • That includes a broad range of characteristics ranging from an enlarged clitoris or a misplaced urethra opening on the penis to genitalia that don't clearly match one gender. (
  • Parents might consider how they can help their daughters to feel more positively about their bodies, such as by teaching them accurate names for their body parts, including their genitals (e.g., "vulva" rather than "down there") and responding in supportive ways to their self-exploration. (
  • The external genitalia are the accessory structures of the female reproductive system that are external to the vagina . (
  • The external genitalia include the labia majora , mons pubis , labia minora, clitoris , and glands within the vestibule . (
  • The internal genitals include the testicles, or testes, epididymis and vas deferens (housed in the scrotum), the seminal vesicles, the prostate gland, the ejaculatory ducts, the Cowper's gland, and the urethra. (
  • There are three basic configurations of genitalia in the majority of the Lepidoptera based on how the arrangement in females of openings for copulation, fertilisation and egg-laying has evolved: Exoporian : Hepialidae and related families have an external groove that carries sperm from the copulatory opening (gonopore) to the (ovipore) and are termed Exoporian. (
  • The hooked male genitalia of mosquitofish is seen as an evolutionary response to females' blocked genital pore. (
  • The researchers were astonished to discover that the females of four Neotrogla species from extremely dry Brazlian caves had penislike genitals dubbed gynosomes, a complex organ composed of muscles, ducts, membranes and spikes. (
  • An alleged escort was arrested and charged with attempted murder for biting a man's genitals in an Orange County hotel room, deputies said. (
  • Those can include trauma after sex, a urinary tract infection, piercing of the genitals, getting a prosthetic penile implant, or having a foreign object in the rectum. (
  • Infant male and female genitalia set in tan skin tone for use with Nursing Baby manikins for urinary catheterization and rectal suppository insertion procedures. (
  • Ambiguity of a newborn's genitalia or clinical situations in which determining the sex of a newborn is not clear represent a true dilemma in the nursery. (
  • Your newborn girl's genitals have been exposed to many hormones in the uterus. (
  • 5) History of major abnormalities or defects of the genitalia such as change of sex (P64.5), hermaphroditism, pseudohermaphroditism, or pure gonadal dysgenesis (752.7) or dysfunctional residuals from surgical correction of these conditions is disqualifying. (
  • In addition to impairing normal brain development, a lack of functional ARX protein disrupts cell differentiation during the formation of the testes, leading to abnormal genitalia. (
  • But Tschopp thinks that the results might at least partially explain why, in the case of certain congenital diseases, deformed arms and legs are often coupled with damage to the external genitals. (
  • The study of the genitalia of Lepidoptera is important for Lepidoptera taxonomy in addition to development, anatomy and natural history. (
  • The history of Bahamas mosquitofish is written in their genitals. (
  • Another trait evolving differently across mosquitofish populations is their genitals. (
  • In the past, researchers studying mosquitofish-and other rapidly changing species-have focused on male genitalia. (
  • In an earlier study , Langerhans found that male mosquitofish living with predators have evolved different genitalia too. (
  • It might seem that Langerhans has exhausted the questions there are to ask about mosquitofish genitals. (
  • NC State Ph.D. student Justa Heinen-Kay and assistant professor of biological sciences R. Brian Langerhans show, in a paper published in the journal Evolutionary Applications , that the male genitalia of three different species of Bahamian mosquitofish ( Gambusia ) living in fragmented waters differ markedly from the genitalia of fish living in unfragmented waters. (
  • Fragmentation limits the number of mosquitofish predators, which appears to have a link to the shape of the male fish's genitalia. (
  • Many women still have no idea what their genitals really look like - and how they look in comparison with other women's genitals. (
  • An Indiana University study published in the September issue of the International Journal of Sexual Health found that women who feel more positively about women's genitals find it easier to orgasm and are more likely to engage in sexual health promoting behaviors, such as having regular gynecological exams or performing vulvar self-examinations. (
  • Our culture often portrays women's genitals as dirty and in need of cleaning and grooming. (
  • Herbenick's study created a scale for measuring men's and women's attitudes toward women's genitals. (
  • The study also found that men had more positive attitudes about women's genitals than women. (
  • What we found in this study is that men generally feel positive about a variety of aspects of women's genitals including how they look, smell, taste and feel. (
  • Indeed, Leo Steinberg has persuasively proposed, in his The Sexuality of Christ in Renaissance Art and in Modern Oblivion (recently issued in a revised and expanded second edition), 2 that from before 1400 to the mid-sixteenth century, European religious art emphasized the genitals of the infant Jesus and the dead Christ in an ostentatio genitalium that enforced the doctrine of the divine incarnation. (
  • The genitalia are complex and provide the basis for species discrimination in most families and also in family identification. (
  • The uniqueness of genitalia of a species led to the use of the morphological study of genitalia as one of the most important keys in taxonomic identification of taxa below family level. (
  • Genitalia in male and female of any particular Lepidopteran species are adapted to fit each other like a lock (female) and key (male). (
  • Did you know ducks have probably the most interesting genitals of all bird species? (
  • A magnified view of the four-hooked genitalia of the newly identified fish species Gambusia quadruncus. (
  • Neotrogla species constitute the first cases in nature in which genitalia are reversed," said study co-author Rodrigo Ferreira, a cave biologist at the Federal University of Lavras in Brazil, shown here collecting samples. (
  • Coevolution between male and female genitalia in the Drosophila melanogaster species subgroup. (
  • Here, we re-examined male and female genitalia in the nine species of the D. melanogaster subgroup. (
  • Note the absence of species-specific structures in the male and female genitalia of D. santomea (G, I). Scale bar is 50 µm. (
  • While we expected to see some changes, we were surprised to see the consistency with which each species changed in accordance with our predictions based on earlier work that focused on how ecological factors, such as predation, affected the evolution of male genitalia over the course of thousands of years. (
  • We tested whether anthropogenic habitat fragmentation has resulted in rapid changes in the size, allometry, shape, and meristics of male genitalia in three native species of livebearing fishes (genus: Gambusia) inhabiting tidal creeks across six Bahamian islands. (
  • X-linked lissencephaly with abnormal genitalia (XLAG) is a condition that affects the development of the brain and genitalia. (
  • Miyata R, Hayashi M, Miyai K, Akashi T, Kato M, Kohyama J. Analysis of the hypothalamus in a case of X-linked lissencephaly with abnormal genitalia (XLAG). (
  • When possible avoid expressions like maldeveloped or undeveloped, errors of development, defective genitals, abnormal, or mistakes of nature. (
  • Initial assessment includes physical examination focusing on external genitalia, karyotype, and imaging of internal genitalia. (
  • Langerhans explained that the male's hooked genitals may be a counter-response to the female's own defenses against undesirable mates. (
  • Can Itching in the Genitals Indicate Cancer? (
  • Itching genitals very common worldwide, but is more common in women than in men. (
  • Treatment of genital itching genitals complex, aims to eliminate the cause of the itch (for example, the treatment of candidiasis, the removal of local inflammation). (
  • The evolution of asymmetry in male genitalia is a pervasive and recurrent phenomenon across almost the entire animal kingdom. (
  • Bilateral asymmetry of male genitalia occurs in many animal groups with internal fertilization [ 1 , 2 ], and is especially common in the Platyhelminthes, Arthropoda, Chordata and Nematoda [ 3 ]. (
  • However, genital asymmetry has yet to emerge as a morphological phenomenon in its own right within this conceptual framework for genitalia evolution. (
  • Initial testing can be based on symmetry/asymmetry of genitalia and presence of palpable gonad(s). (
  • The child may have parts of both male and female genitals. (
  • Male and female genitals are divided into external genitals (those visible outside the body) and internal genitals (those that are inside the body). (
  • First off, contrary to some news reports and commentaries, M.C. was not born "with both sets of genitals," male and female. (
  • SACRAMENTO, Calif. (AP) - California doctors would be barred from treating or performing surgery on children born with genitals that don't fit a single gender or are otherwise atypical unless it's medically necessary or the child consents, under a bill unveiled Monday. (
  • Many furries that design their character 's form to include anatomical parts use genitalia that's either human -like, animal , or mix of both. (
  • OKLAHOMA CITY, July 17 (UPI) -- A felon was arrested in Oklahoma City for possession of a firearm after he told police he shot himself in the genitals, officials said. (
  • Yet Langerhans says the shape (not size) of female genitalia, which is somewhat more elongated in predator-free populations, does seem to have evolved along with the changing male shape. (