Marked impairments in the development of motor coordination such that the impairment interferes with activities of daily living. (From DSM-V)
Performance of complex motor acts.
Disturbances considered to be pathological based on age and stage appropriateness, e.g., conduct disturbances and anaclitic depression. This concept does not include psychoneuroses, psychoses, or personality disorders with fixed patterns.
Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
Observable manifestations of impaired psychological functioning.
Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)
Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These disorders may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
Autosomal recessive hereditary disorders characterized by congenital SENSORINEURAL HEARING LOSS and RETINITIS PIGMENTOSA. Genetically and symptomatically heterogeneous, clinical classes include type I, type II, and type III. Their severity, age of onset of retinitis pigmentosa and the degree of vestibular dysfunction are variable.
A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
The observable response an animal makes to any situation.
Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.
Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Persistent and disabling ANXIETY.
Those disorders that have a disturbance in mood as their predominant feature.
Neurons which activate MUSCLE CELLS.
The physical activity of a human or an animal as a behavioral phenomenon.
Special hospitals which provide care for ill children.
The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.
Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)
The coordination of a sensory or ideational (cognitive) process and a motor activity.
Performance of an act one or more times, with a view to its fixation or improvement; any performance of an act or behavior that leads to learning.
Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero.
The term "United States" in a medical context often refers to the country where a patient or study participant resides, and is not a medical term per se, but relevant for epidemiological studies, healthcare policies, and understanding differences in disease prevalence, treatment patterns, and health outcomes across various geographic locations.
Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.
An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.
Disorders related to substance abuse.
Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.
Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.
Disturbances in mental processes related to learning, thinking, reasoning, and judgment.
Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Learning to make a series of responses in exact order.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The detailed examination of observable activity or behavior associated with the execution or completion of a required function or unit of work.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.
A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)
Elements of limited time intervals, contributing to particular results or situations.
Abnormalities of motor function that are associated with organic and non-organic cognitive disorders.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
Intellectual or mental process whereby an organism obtains knowledge.
A performance test based on forced MOTOR ACTIVITY on a rotating rod, usually by a rodent. Parameters include the riding time (seconds) or endurance. Test is used to evaluate balance and coordination of the subjects, particular in experimental animal models for neurological disorders and drug effects.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)
A front limb of a quadruped. (The Random House College Dictionary, 1980)
Proteins that are involved in or cause CELL MOVEMENT such as the rotary structures (flagellar motor) or the structures whose movement is directed along cytoskeletal filaments (MYOSIN; KINESIN; and DYNEIN motor families).
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The time from the onset of a stimulus until a response is observed.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)
A characteristic symptom complex.
The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.
The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Conditions characterized by disturbances of usual sleep patterns or behaviors. Sleep disorders may be divided into three major categories: DYSSOMNIAS (i.e. disorders characterized by insomnia or hypersomnia), PARASOMNIAS (abnormal sleep behaviors), and sleep disorders secondary to medical or psychiatric disorders. (From Thorpy, Sleep Disorders Medicine, 1994, p187)
Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by a another medical condition, by the direct effects of a substance, or by another mental disorder. The symptoms must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)
A technique that involves the use of electrical coils on the head to generate a brief magnetic field which reaches the CEREBRAL CORTEX. It is coupled with ELECTROMYOGRAPHY response detection to assess cortical excitability by the threshold required to induce MOTOR EVOKED POTENTIALS. This method is also used for BRAIN MAPPING, to study NEUROPHYSIOLOGY, and as a substitute for ELECTROCONVULSIVE THERAPY for treating DEPRESSION. Induction of SEIZURES limits its clinical usage.
Conditions characterized by language abilities (comprehension and expression of speech and writing) that are below the expected level for a given age, generally in the absence of an intellectual impairment. These conditions may be associated with DEAFNESS; BRAIN DISEASES; MENTAL DISORDERS; or environmental factors.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Change in learning in one situation due to prior learning in another situation. The transfer can be positive (with second learning improved by first) or negative (where the reverse holds).
Recording of the changes in electric potential of muscle by means of surface or needle electrodes.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Four or five slender jointed digits in humans and primates, attached to each HAND.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
Acquired or developmental conditions marked by an impaired ability to comprehend or generate spoken forms of language.
A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
The gradual expansion in complexity and meaning of symbols and sounds as perceived and interpreted by the individual through a maturational and learning process. Stages in development include babbling, cooing, word imitation with cognition, and use of short sentences.
Disorders characterized by proliferation of lymphoid tissue, general or unspecified.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
A group of cognitive disorders characterized by the inability to perform previously learned skills that cannot be attributed to deficits of motor or sensory function. The two major subtypes of this condition are ideomotor (see APRAXIA, IDEOMOTOR) and ideational apraxia, which refers to loss of the ability to mentally formulate the processes involved with performing an action. For example, dressing apraxia may result from an inability to mentally formulate the act of placing clothes on the body. Apraxias are generally associated with lesions of the dominant PARIETAL LOBE and supramarginal gyrus. (From Adams et al., Principles of Neurology, 6th ed, pp56-7)
Includes two similar disorders: oppositional defiant disorder and CONDUCT DISORDERS. Symptoms occurring in children with these disorders include: defiance of authority figures, angry outbursts, and other antisocial behaviors.
A disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, including the ELASTIN gene. Clinical manifestations include SUPRAVALVULAR AORTIC STENOSIS; MENTAL RETARDATION; elfin facies; impaired visuospatial constructive abilities; and transient HYPERCALCEMIA in infancy. The condition affects both sexes, with onset at birth or in early infancy.
Disorders related to or resulting from abuse or mis-use of alcohol.
Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.
Any observable response or action of a child from 24 months through 12 years of age. For neonates or children younger than 24 months, INFANT BEHAVIOR is available.
Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.
The persistence to perform a learned behavior (facts or experiences) after an interval has elapsed in which there has been no performance or practice of the behavior.
Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
An infant during the first month after birth.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Neurotic reactions to unusual, severe, or overwhelming military stress.
The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions.
Any behavior caused by or affecting another individual, usually of the same species.
An outbred strain of rats developed in 1915 by crossing several Wistar Institute white females with a wild gray male. Inbred strains have been derived from this original outbred strain, including Long-Evans cinnamon rats (RATS, INBRED LEC) and Otsuka-Long-Evans-Tokushima Fatty rats (RATS, INBRED OLETF), which are models for Wilson's disease and non-insulin dependent diabetes mellitus, respectively.
A general term referring to a mild to moderate degree of muscular weakness, occasionally used as a synonym for PARALYSIS (severe or complete loss of motor function). In the older literature, paresis often referred specifically to paretic neurosyphilis (see NEUROSYPHILIS). "General paresis" and "general paralysis" may still carry that connotation. Bilateral lower extremity paresis is referred to as PARAPARESIS.
Neural tracts connecting one part of the nervous system with another.
Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994)
The observable response of a man or animal to a situation.
A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
The capability to perform acceptably those duties directly related to patient care.
A direct form of psychotherapy based on the interpretation of situations (cognitive structure of experiences) that determine how an individual feels and behaves. It is based on the premise that cognition, the process of acquiring knowledge and forming beliefs, is a primary determinant of mood and behavior. The therapy uses behavioral and verbal techniques to identify and correct negative thinking that is at the root of the aberrant behavior.
Developmental bone diseases are a category of skeletal disorders that arise from disturbances in the normal growth and development of bones, including abnormalities in size, shape, structure, or composition, which can lead to various musculoskeletal impairments and deformities.
The application of modern theories of learning and conditioning in the treatment of behavior disorders.
A directed conversation aimed at eliciting information for psychiatric diagnosis, evaluation, treatment planning, etc. The interview may be conducted by a social worker or psychologist.
Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.
The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
A principle that learning is facilitated when the learner receives immediate evaluation of learning performance. The concept also hypothesizes that learning is facilitated when the learner is promptly informed whether a response is correct, and, if incorrect, of the direction of error.
Genes that influence the PHENOTYPE only in the homozygous state.
A disorder associated with three or more of the following: eating until feeling uncomfortably full; eating large amounts of food when not physically hungry; eating much more rapidly than normal; eating alone due to embarrassment; feeling of disgust, DEPRESSION, or guilt after overeating. Criteria includes occurrence on average, at least 2 days a week for 6 months. The binge eating is not associated with the regular use of inappropriate compensatory behavior (i.e. purging, excessive exercise, etc.) and does not co-occur exclusively with BULIMIA NERVOSA or ANOREXIA NERVOSA. (From DSM-IV, 1994)
The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.
A POSTURE in which an ideal body mass distribution is achieved. Postural balance provides the body carriage stability and conditions for normal functions in stationary position or in movement, such as sitting, standing, or walking.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Congenital structural abnormalities and deformities of the musculoskeletal system.
The superior part of the upper extremity between the SHOULDER and the ELBOW.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Sudden temporary alterations in the normally integrative functions of consciousness.
Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. (DSM-IV)
Detection of a MUTATION; GENOTYPE; KARYOTYPE; or specific ALLELES associated with genetic traits, heritable diseases, or predisposition to a disease, or that may lead to the disease in descendants. It includes prenatal genetic testing.
A readily reversible suspension of sensorimotor interaction with the environment, usually associated with recumbency and immobility.
Sound that expresses emotion through rhythm, melody, and harmony.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Stress wherein emotional factors predominate.
A state of harmony between internal needs and external demands and the processes used in achieving this condition. (From APA Thesaurus of Psychological Index Terms, 8th ed)
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
A mechanism of communication within a system in that the input signal generates an output response which returns to influence the continued activity or productivity of that system.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.

Motor skills disorders are conditions that affect a person's ability to perform coordinated movements. These movements can be simple, such as buttoning a shirt, or complex, such as playing a musical instrument. Motor skills disorders can make it difficult for a person to perform everyday activities and can impact their quality of life.

There are two main types of motor skills: fine motor skills and gross motor skills. Fine motor skills involve the small movements of the hands, fingers, and wrists, such as writing or using utensils. Gross motor skills involve larger movements of the arms, legs, and torso, such as crawling, walking, or running.

Motor skills disorders can affect either fine or gross motor skills, or both. Some common types of motor skills disorders include:

* Developmental coordination disorder (DCD): a condition that affects a child's ability to perform coordinated movements and is often diagnosed in early childhood. Children with DCD may have difficulty with tasks such as tying their shoes, buttoning their clothes, or using scissors.
* Cerebral palsy: a group of disorders that affect movement and muscle tone, caused by damage to the brain before, during, or after birth. Cerebral palsy can cause stiff or floppy muscles, uncontrolled movements, and difficulty with balance and coordination.
* Dyspraxia: a condition that affects a person's ability to plan and perform coordinated movements. People with dyspraxia may have difficulty with tasks such as writing, buttoning their clothes, or playing sports.
* Ataxia: a group of disorders that affect coordination and balance, caused by damage to the cerebellum (the part of the brain that controls movement). Ataxia can cause unsteady gait, poor coordination, and difficulty with fine motor tasks.

Motor skills disorders can be caused by a variety of factors, including genetics, injury, illness, or developmental delays. Treatment for motor skills disorders may include physical therapy, occupational therapy, speech therapy, and medication. In some cases, surgery may also be necessary to treat the underlying cause of the disorder.

Motor skills are defined as the abilities required to plan, control and execute physical movements. They involve a complex interplay between the brain, nerves, muscles, and the environment. Motor skills can be broadly categorized into two types: fine motor skills, which involve small, precise movements (such as writing or picking up small objects), and gross motor skills, which involve larger movements using the arms, legs, and torso (such as crawling, walking, or running).

Motor skills development is an essential aspect of child growth and development, and it continues to evolve throughout adulthood. Difficulties with motor skills can impact a person's ability to perform daily activities and can be associated with various neurological and musculoskeletal conditions.

Childhood behavior disorders are a group of disruptive behaviors that are more frequent or severe than is typical for the child's age and development. These behaviors can cause significant impairment in the child's life, including their relationships with family, friends, and at school. Common examples of childhood behavior disorders include:

1. Attention Deficit Hyperactivity Disorder (ADHD): A chronic condition characterized by difficulty paying attention, impulsivity, and hyperactivity.
2. Oppositional Defiant Disorder (ODD): A pattern of negative, hostile, and defiant behavior towards authority figures.
3. Conduct Disorder: A repetitive and persistent pattern of behavior that violates the rights of others or major age-appropriate societal norms or rules.
4. Intermittent Explosive Disorder (IED): A disorder characterized by recurrent impulsive aggressive behavior disproportionate to the situation.
5. Autism Spectrum Disorder (ASD): A neurodevelopmental disorder characterized by difficulties in social interaction, communication, and repetitive behaviors.
6. Tourette Syndrome: A neurological disorder characterized by repetitive, involuntary movements and vocalizations called tics.

It's important to note that children with behavior disorders often have other conditions such as learning disabilities, mood disorders, or anxiety disorders. Early identification and treatment of these disorders can significantly improve the child's outcome.

A mental disorder is a syndrome characterized by clinically significant disturbance in an individual's cognition, emotion regulation, or behavior. It's associated with distress and/or impaired functioning in social, occupational, or other important areas of life, often leading to a decrease in quality of life. These disorders are typically persistent and can be severe and disabling. They may be related to factors such as genetics, early childhood experiences, or trauma. Examples include depression, anxiety disorders, bipolar disorder, schizophrenia, and personality disorders. It's important to note that a diagnosis should be made by a qualified mental health professional.

Behavioral symptoms refer to changes or abnormalities in a person's behavior, which may be indicative of an underlying medical or psychological condition. These symptoms can manifest as a wide range of observable behaviors that are unusual, disruptive, or distressing for the individual experiencing them or those around them. Examples of behavioral symptoms include:

1. Agitation: A state of irritability, restlessness, or excitement, often accompanied by aggressive or disruptive behavior.
2. Aggression: Hostile or violent behavior directed towards others, including verbal or physical attacks.
3. Apathy: A lack of interest, motivation, or emotion, often leading to social withdrawal and decreased activity levels.
4. Changes in appetite or sleep patterns: Significant fluctuations in the amount or frequency of food intake or sleep, which can be indicative of various medical or psychological conditions.
5. Disinhibition: A loss of restraint or impulse control, leading to inappropriate behavior in social situations.
6. Hallucinations: Perception of sensory stimuli (such as sight, sound, touch) without an external source, often associated with certain mental illnesses or neurological disorders.
7. Hyperactivity: Increased activity levels, often accompanied by impulsivity and difficulty focusing attention.
8. Impaired judgment: Poor decision-making abilities, often resulting in risky or harmful behavior.
9. Inattention: Difficulty focusing or sustaining attention on a task or activity.
10. Mood changes: Fluctuations in emotional state, such as depression, anxiety, or euphoria.
11. Psychosis: A severe mental disorder characterized by detachment from reality, hallucinations, and disorganized thinking or behavior.
12. Repetitive behaviors: Engaging in repetitive actions or movements, often associated with certain developmental disorders or neurological conditions.
13. Social withdrawal: Avoidance of social interactions or activities, often indicative of depression, anxiety, or other mental health concerns.
14. Thought disturbances: Disorganized or disrupted thinking patterns, such as racing thoughts, tangential thinking, or loose associations between ideas.

Behavioral symptoms can be caused by various factors, including medical conditions (such as infections, brain injuries, or neurodegenerative diseases), mental health disorders (such as depression, anxiety, bipolar disorder, or schizophrenia), substance abuse, and environmental factors (such as stress or trauma). Accurate assessment and diagnosis are crucial for determining appropriate treatment interventions.

Developmental disabilities are a group of conditions that arise in childhood and are characterized by significant impairments in cognitive functioning, physical development, or both. These disabilities can affect various areas of an individual's life, including their ability to learn, communicate, socialize, and take care of themselves.

Examples of developmental disabilities include intellectual disabilities, cerebral palsy, autism spectrum disorder, Down syndrome, and fetal alcohol spectrum disorders. These conditions are typically diagnosed in childhood and can persist throughout an individual's life.

The causes of developmental disabilities are varied and can include genetic factors, environmental influences, and complications during pregnancy or childbirth. In some cases, the exact cause may be unknown.

It is important to note that individuals with developmental disabilities have unique strengths and abilities, as well as challenges. With appropriate support and services, they can lead fulfilling lives and participate actively in their communities.

Autistic Disorder, also known as Autism or Classic Autism, is a neurodevelopmental disorder that affects communication and behavior. It is characterized by:

1. Persistent deficits in social communication and social interaction across multiple contexts, including:
* Deficits in social-emotional reciprocity;
* Deficits in nonverbal communicative behaviors used for social interaction;
* Deficits in developing, maintaining, and understanding relationships.
2. Restricted, repetitive patterns of behavior, interests, or activities, as manifested by at least two of the following:
* Stereotyped or repetitive motor movements, use of objects, or speech;
* Insistence on sameness, inflexible adherence to routines, or ritualized patterns of verbal or nonverbal behavior;
* Highly restricted, fixated interests that are abnormal in intensity or focus;
* Hyper- or hyporeactivity to sensory input or unusual interest in sensory aspects of the environment.
3. Symptoms must be present in the early developmental period (but may not become fully manifest until social demands exceed limited capacities) and limit or impair everyday functioning.
4. Symptoms do not occur exclusively during the course of a schizophrenia spectrum disorder or other psychotic disorders.

Autistic Disorder is part of the autism spectrum disorders (ASDs), which also include Asperger's Syndrome and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS). The current diagnostic term for this category of conditions, according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), is Autism Spectrum Disorder.

Attention Deficit Hyperactivity Disorder (ADHD) with hyperactivity is a neurodevelopmental disorder that affects both children and adults. The condition is characterized by symptoms including:

1. Difficulty paying attention or staying focused on a single task
2. Impulsivity, or acting without thinking
3. Hyperactivity, or excessive fidgeting, restlessness, or talking

In order to be diagnosed with ADHD with hyperactivity, an individual must exhibit these symptoms to a degree that is developmentally inappropriate and interferes with their daily functioning. Additionally, the symptoms must have been present for at least six months and be present in multiple settings (e.g., at home, school, work).

It's important to note that ADHD can manifest differently in different people, and some individuals may experience predominantly inattentive or impulsive symptoms rather than hyperactive ones. However, when the hyperactive component is prominent, it is referred to as ADHD with hyperactivity.

Effective treatments for ADHD with hyperactivity include a combination of medication (such as stimulants) and behavioral therapy. With appropriate treatment, individuals with ADHD can learn to manage their symptoms and lead successful, fulfilling lives.

Intellectual disability (ID) is a term used when there are significant limitations in both intellectual functioning and adaptive behavior, which covers many everyday social and practical skills. This disability originates before the age of 18.

Intellectual functioning, also known as intelligence, refers to general mental capacity, such as learning, reasoning, problem-solving, and other cognitive skills. Adaptive behavior includes skills needed for day-to-day life, such as communication, self-care, social skills, safety judgement, and basic academic skills.

Intellectual disability is characterized by below-average intelligence or mental ability and a lack of skills necessary for day-to-day living. It can be mild, moderate, severe, or profound, depending on the degree of limitation in intellectual functioning and adaptive behavior.

It's important to note that people with intellectual disabilities have unique strengths and limitations, just like everyone else. With appropriate support and education, they can lead fulfilling lives and contribute to their communities in many ways.

A learning disorder is a neurodevelopmental disorder that affects an individual's ability to acquire, process, and use information in one or more academic areas despite normal intelligence and adequate instruction. It can manifest as difficulties with reading (dyslexia), writing (dysgraphia), mathematics (dyscalculia), or other academic skills. Learning disorders are not the result of low intelligence, lack of motivation, or environmental factors alone, but rather reflect a significant discrepancy between an individual's cognitive abilities and their academic achievement. They can significantly impact a person's ability to perform in school, at work, and in daily life, making it important to diagnose and manage these disorders effectively.

Usher Syndromes are a group of genetic disorders that are characterized by hearing loss and visual impairment due to retinitis pigmentosa. They are the most common cause of deafblindness in developed countries. There are three types of Usher Syndromes (Type 1, Type 2, and Type 3) which differ in the age of onset, severity, and progression of hearing loss and vision loss.

Type 1 Usher Syndrome is the most severe form, with profound deafness present at birth or within the first year of life, and retinitis pigmentosa leading to significant vision loss by the teenage years. Type 2 Usher Syndrome is characterized by moderate to severe hearing loss beginning in childhood and vision loss due to retinitis pigmentosa starting in adolescence or early adulthood. Type 3 Usher Syndrome has progressive hearing loss that begins in adolescence and vision loss due to retinitis pigmentosa starting in the third decade of life.

The diagnosis of Usher Syndromes is based on a combination of clinical examination, audiological evaluation, and genetic testing. There is currently no cure for Usher Syndromes, but various assistive devices and therapies can help manage the symptoms and improve quality of life.

Bipolar disorder, also known as manic-depressive illness, is a mental health condition that causes extreme mood swings that include emotional highs (mania or hypomania) and lows (depression). When you become depressed, you may feel sad or hopeless and lose interest or pleasure in most activities. When your mood shifts to mania or hypomania (a less severe form of mania), you may feel euphoric, full of energy, or unusually irritable. These mood swings can significantly affect your job, school, relationships, and overall quality of life.

Bipolar disorder is typically characterized by the presence of one or more manic or hypomanic episodes, often accompanied by depressive episodes. The episodes may be separated by periods of normal mood, but in some cases, a person may experience rapid cycling between mania and depression.

There are several types of bipolar disorder, including:

* Bipolar I Disorder: This type is characterized by the occurrence of at least one manic episode, which may be preceded or followed by hypomanic or major depressive episodes.
* Bipolar II Disorder: This type involves the presence of at least one major depressive episode and at least one hypomanic episode, but no manic episodes.
* Cyclothymic Disorder: This type is characterized by numerous periods of hypomania and depression that are not severe enough to meet the criteria for a full manic or depressive episode.
* Other Specified and Unspecified Bipolar and Related Disorders: These categories include bipolar disorders that do not fit the criteria for any of the other types.

The exact cause of bipolar disorder is unknown, but it appears to be related to a combination of genetic, environmental, and neurochemical factors. Treatment typically involves a combination of medication, psychotherapy, and lifestyle changes to help manage symptoms and prevent relapses.

'Animal behavior' refers to the actions or responses of animals to various stimuli, including their interactions with the environment and other individuals. It is the study of the actions of animals, whether they are instinctual, learned, or a combination of both. Animal behavior includes communication, mating, foraging, predator avoidance, and social organization, among other things. The scientific study of animal behavior is called ethology. This field seeks to understand the evolutionary basis for behaviors as well as their physiological and psychological mechanisms.

The motor cortex is a region in the frontal lobe of the brain that is responsible for controlling voluntary movements. It is involved in planning, initiating, and executing movements of the limbs, body, and face. The motor cortex contains neurons called Betz cells, which have large cell bodies and are responsible for transmitting signals to the spinal cord to activate muscles. Damage to the motor cortex can result in various movement disorders such as hemiplegia or paralysis on one side of the body.

In the context of medicine and healthcare, learning is often discussed in relation to learning abilities or disabilities that may impact an individual's capacity to acquire, process, retain, and apply new information or skills. Learning can be defined as the process of acquiring knowledge, understanding, behaviors, and skills through experience, instruction, or observation.

Learning disorders, also known as learning disabilities, are a type of neurodevelopmental disorder that affects an individual's ability to learn and process information in one or more areas, such as reading, writing, mathematics, or reasoning. These disorders are not related to intelligence or motivation but rather result from differences in the way the brain processes information.

It is important to note that learning can also be influenced by various factors, including age, cognitive abilities, physical and mental health status, cultural background, and educational experiences. Therefore, a comprehensive assessment of an individual's learning abilities and needs should take into account these various factors to provide appropriate support and interventions.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

Anxiety disorders are a category of mental health disorders characterized by feelings of excessive and persistent worry, fear, or anxiety that interfere with daily activities. They include several different types of disorders, such as:

1. Generalized Anxiety Disorder (GAD): This is characterized by chronic and exaggerated worry and tension, even when there is little or nothing to provoke it.
2. Panic Disorder: This is characterized by recurring unexpected panic attacks and fear of experiencing more panic attacks.
3. Social Anxiety Disorder (SAD): Also known as social phobia, this is characterized by excessive fear, anxiety, or avoidance of social situations due to feelings of embarrassment, self-consciousness, and concern about being judged or viewed negatively by others.
4. Phobias: These are intense, irrational fears of certain objects, places, or situations. When a person with a phobia encounters the object or situation they fear, they may experience panic attacks or other severe anxiety responses.
5. Agoraphobia: This is a fear of being in places where it may be difficult to escape or get help if one has a panic attack or other embarrassing or incapacitating symptoms.
6. Separation Anxiety Disorder (SAD): This is characterized by excessive anxiety about separation from home or from people to whom the individual has a strong emotional attachment (such as a parent, sibling, or partner).
7. Selective Mutism: This is a disorder where a child becomes mute in certain situations, such as at school, but can speak normally at home or with close family members.

These disorders are treatable with a combination of medication and psychotherapy (cognitive-behavioral therapy, exposure therapy). It's important to seek professional help if you suspect that you or someone you know may have an anxiety disorder.

Mood disorders are a category of mental health disorders characterized by significant and persistent changes in mood, affect, and emotional state. These disorders can cause disturbances in normal functioning and significantly impair an individual's ability to carry out their daily activities. The two primary types of mood disorders are depressive disorders (such as major depressive disorder or persistent depressive disorder) and bipolar disorders (which include bipolar I disorder, bipolar II disorder, and cyclothymic disorder).

Depressive disorders involve prolonged periods of low mood, sadness, hopelessness, and a lack of interest in activities. Individuals with these disorders may also experience changes in sleep patterns, appetite, energy levels, concentration, and self-esteem. In severe cases, they might have thoughts of death or suicide.

Bipolar disorders involve alternating episodes of mania (or hypomania) and depression. During a manic episode, individuals may feel extremely elated, energetic, or irritable, with racing thoughts, rapid speech, and impulsive behavior. They might engage in risky activities, have decreased sleep needs, and display poor judgment. In contrast, depressive episodes involve the same symptoms as depressive disorders.

Mood disorders can be caused by a combination of genetic, biological, environmental, and psychological factors. Proper diagnosis and treatment, which may include psychotherapy, medication, or a combination of both, are essential for managing these conditions and improving quality of life.

Motor neurons are specialized nerve cells in the brain and spinal cord that play a crucial role in controlling voluntary muscle movements. They transmit electrical signals from the brain to the muscles, enabling us to perform actions such as walking, talking, and swallowing. There are two types of motor neurons: upper motor neurons, which originate in the brain's motor cortex and travel down to the brainstem and spinal cord; and lower motor neurons, which extend from the brainstem and spinal cord to the muscles. Damage or degeneration of these motor neurons can lead to various neurological disorders, such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).

"Motor activity" is a general term used in the field of medicine and neuroscience to refer to any kind of physical movement or action that is generated by the body's motor system. The motor system includes the brain, spinal cord, nerves, and muscles that work together to produce movements such as walking, talking, reaching for an object, or even subtle actions like moving your eyes.

Motor activity can be voluntary, meaning it is initiated intentionally by the individual, or involuntary, meaning it is triggered automatically by the nervous system without conscious control. Examples of voluntary motor activity include deliberately lifting your arm or kicking a ball, while examples of involuntary motor activity include heartbeat, digestion, and reflex actions like jerking your hand away from a hot stove.

Abnormalities in motor activity can be a sign of neurological or muscular disorders, such as Parkinson's disease, cerebral palsy, or multiple sclerosis. Assessment of motor activity is often used in the diagnosis and treatment of these conditions.

A pediatric hospital is a specialized medical facility that provides comprehensive healthcare services for infants, children, adolescents, and young adults up to the age of 21. These hospitals employ medical professionals with expertise in treating various childhood illnesses, injuries, and developmental disorders. The facilities are designed to cater to the unique needs of children, including child-friendly environments, specialized equipment, and age-appropriate care.

Pediatric hospitals offer a wide range of services such as inpatient and outpatient care, emergency services, surgical procedures, diagnostic testing, rehabilitation, and mental health services. They also focus on preventive healthcare, family-centered care, and education to support the overall well-being of their young patients. Some pediatric hospitals may specialize further, focusing on specific areas such as cancer treatment, cardiology, neurology, or orthopedics.

Evoked potentials, motor, are a category of tests used in clinical neurophysiology to measure the electrical activity generated by the nervous system in response to a stimulus that specifically activates the motor pathways. These tests can help assess the integrity and function of the motor neurons, which are responsible for controlling voluntary muscle movements.

During a motor evoked potentials test, electrodes are placed on the scalp or directly on the surface of the brain or spinal cord. A stimulus is then applied to the motor cortex or peripheral nerves, causing the muscles to contract. The resulting electrical signals are recorded and analyzed to evaluate the conduction velocity, amplitude, and latency of the motor responses.

Motor evoked potentials tests can be useful in diagnosing various neurological conditions, such as multiple sclerosis, spinal cord injuries, and motor neuron diseases. They can also help monitor the progression of these conditions and assess the effectiveness of treatments.

The Diagnostic and Statistical Manual of Mental Disorders (DSM) is a publication of the American Psychiatric Association (APA) that provides diagnostic criteria for mental disorders. It is widely used by mental health professionals in the United States and around the world to diagnose and classify mental health conditions.

The DSM includes detailed descriptions of symptoms, clinical examples, and specific criteria for each disorder, which are intended to facilitate accurate diagnosis and improve communication among mental health professionals. The manual is regularly updated to reflect current research and clinical practice, with the most recent edition being the DSM-5, published in 2013.

It's important to note that while the DSM is a valuable tool for mental health professionals, it is not without controversy. Some critics argue that the manual medicalizes normal human experiences and that its categories may be too broad or overlapping. Nonetheless, it remains an essential resource for clinicians, researchers, and policymakers in the field of mental health.

Psychomotor performance refers to the integration and coordination of mental processes (cognitive functions) with physical movements. It involves the ability to perform complex tasks that require both cognitive skills, such as thinking, remembering, and perceiving, and motor skills, such as gross and fine motor movements. Examples of psychomotor performances include driving a car, playing a musical instrument, or performing surgical procedures.

In a medical context, psychomotor performance is often used to assess an individual's ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs), such as bathing, dressing, cooking, cleaning, and managing medications. Deficits in psychomotor performance can be a sign of neurological or psychiatric disorders, such as dementia, Parkinson's disease, or depression.

Assessment of psychomotor performance may involve tests that measure reaction time, coordination, speed, precision, and accuracy of movements, as well as cognitive functions such as attention, memory, and problem-solving skills. These assessments can help healthcare professionals develop appropriate treatment plans and monitor the progression of diseases or the effectiveness of interventions.

Inborn genetic diseases, also known as inherited genetic disorders, are conditions caused by abnormalities in an individual's DNA that are present at conception. These abnormalities can include mutations, deletions, or rearrangements of genes or chromosomes. In many cases, these genetic changes are inherited from one or both parents and may be passed down through families.

Inborn genetic diseases can affect any part of the body and can cause a wide range of symptoms, which can vary in severity depending on the specific disorder. Some genetic disorders are caused by mutations in a single gene, while others are caused by changes in multiple genes or chromosomes. In some cases, environmental factors may also contribute to the development of these conditions.

Examples of inborn genetic diseases include cystic fibrosis, sickle cell anemia, Huntington's disease, Duchenne muscular dystrophy, and Down syndrome. These conditions can have significant impacts on an individual's health and quality of life, and many require ongoing medical management and treatment. In some cases, genetic counseling and testing may be recommended for individuals with a family history of a particular genetic disorder to help them make informed decisions about their reproductive options.

I'm sorry for any confusion, but "United States" is a geopolitical entity, specifically the name of the country consisting of 50 states, and it is not a medical term or concept. Therefore, I can't provide a medical definition for it. If you have any questions related to health, medicine, or biology, I would be happy to try to help answer those!

Major Depressive Disorder (MDD), also simply referred to as depression, is a serious mental health condition characterized by the presence of one or more major depressive episodes. A major depressive episode is a period of at least two weeks during which an individual experiences a severely depressed mood and/or loss of interest or pleasure in nearly all activities, accompanied by at least four additional symptoms such as significant changes in appetite or weight, sleep disturbances, psychomotor agitation or retardation, fatigue or loss of energy, feelings of worthlessness or excessive guilt, difficulty thinking, concentrating, or making decisions, and recurrent thoughts of death or suicide.

MDD can significantly impair an individual's ability to function in daily life, and it is associated with increased risks of suicide, substance abuse, and other mental health disorders. The exact cause of MDD is not fully understood, but it is believed to result from a complex interplay of genetic, biological, environmental, and psychological factors. Treatment typically involves a combination of psychotherapy (such as cognitive-behavioral therapy) and medication (such as selective serotonin reuptake inhibitors or tricyclic antidepressants).

Movement disorders are a group of neurological conditions that affect the control and coordination of voluntary movements. These disorders can result from damage to or dysfunction of the cerebellum, basal ganglia, or other parts of the brain that regulate movement. Symptoms may include tremors, rigidity, bradykinesia (slowness of movement), akathisia (restlessness and inability to remain still), dystonia (sustained muscle contractions leading to abnormal postures), chorea (rapid, unpredictable movements), tics, and gait disturbances. Examples of movement disorders include Parkinson's disease, Huntington's disease, Tourette syndrome, and dystonic disorders.

A depressive disorder is a mental health condition characterized by persistent feelings of sadness, hopelessness, and loss of interest or pleasure in activities. It can also include changes in sleep, appetite, energy levels, concentration, and self-esteem, as well as thoughts of death or suicide. Depressive disorders can vary in severity and duration, with some people experiencing mild and occasional symptoms, while others may have severe and chronic symptoms that interfere with their ability to function in daily life.

There are several types of depressive disorders, including major depressive disorder (MDD), persistent depressive disorder (PDD), and postpartum depression. MDD is characterized by symptoms that interfere significantly with a person's ability to function and last for at least two weeks, while PDD involves chronic low-grade depression that lasts for two years or more. Postpartum depression occurs in women after childbirth and can range from mild to severe.

Depressive disorders are thought to be caused by a combination of genetic, biological, environmental, and psychological factors. Treatment typically involves a combination of medication, psychotherapy (talk therapy), and lifestyle changes.

In the context of medicine and healthcare, "movement" refers to the act or process of changing physical location or position. It involves the contraction and relaxation of muscles, which allows for the joints to move and the body to be in motion. Movement can also refer to the ability of a patient to move a specific body part or limb, which is assessed during physical examinations. Additionally, "movement" can describe the progression or spread of a disease within the body.

Obsessive-Compulsive Disorder (OCD) is a mental health disorder characterized by the presence of obsessions and compulsions. Obsessions are recurrent and persistent thoughts, urges, or images that are intrusive, unwanted, and often distressing. Compulsions are repetitive behaviors or mental acts that an individual feels driven to perform in response to an obsession or according to rigid rules, and which are aimed at preventing or reducing anxiety or distress, or preventing some dreaded event or situation. These obsessions and/or compulsions cause significant distress, take up a lot of time (an hour or more a day), and interfere with the individual's daily life, including social activities, relationships, and work or school performance. OCD is considered a type of anxiety disorder and can also co-occur with other mental health conditions.

Post-traumatic stress disorder (PTSD) is a psychiatric condition that can occur in people who have experienced or witnessed a traumatic event such as a natural disaster, serious accident, war combat, rape, or violent personal assault. According to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5), PTSD is characterized by the following symptoms, which must last for more than one month:

1. Intrusion symptoms: These include distressing memories, nightmares, flashbacks, or intense psychological distress or reactivity to internal or external cues that symbolize or resemble an aspect of the traumatic event.
2. Avoidance symptoms: Persistent avoidance of stimuli associated with the traumatic event, including thoughts, feelings, conversations, activities, places, or people.
3. Negative alterations in cognitions and mood: This includes negative beliefs about oneself, others, or the world; distorted blame of self or others for causing the trauma; persistent negative emotional state; decreased interest in significant activities; and feelings of detachment or estrangement from others.
4. Alterations in arousal and reactivity: This includes irritable behavior and angry outbursts, reckless or self-destructive behavior, hypervigilance, exaggerated startle response, problems with concentration, and sleep disturbance.
5. Duration of symptoms: The symptoms must last for more than one month.
6. Functional significance: The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.

It is essential to note that PTSD can occur at any age and can be accompanied by various physical and mental health problems, such as depression, substance abuse, memory problems, and other difficulties in cognition. Appropriate treatment, which may include psychotherapy, medication, or a combination of both, can significantly improve the symptoms and overall quality of life for individuals with PTSD.

Substance-related disorders, as defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), refer to a group of conditions caused by the use of substances such as alcohol, drugs, or medicines. These disorders are characterized by a problematic pattern of using a substance that leads to clinically significant impairment or distress. They can be divided into two main categories: substance use disorders and substance-induced disorders. Substance use disorders involve a pattern of compulsive use despite negative consequences, while substance-induced disorders include conditions such as intoxication, withdrawal, and substance/medication-induced mental disorders. The specific diagnosis depends on the type of substance involved, the patterns of use, and the presence or absence of physiological dependence.

Pervasive developmental disorders (PDD) are a group of conditions that affect the development and functioning of the brain, leading to delays in many areas of development. The American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) has replaced the term "pervasive developmental disorders" with "autism spectrum disorder" and "other neurodevelopmental disorders."

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and interaction across multiple contexts, as well as restricted, repetitive patterns of behavior, interests, or activities. The symptoms of ASD can range from mild to severe, and the condition affects approximately 1 in 54 children in the United States.

Other neurodevelopmental disorders that were previously classified as PDDs include:

1. Intellectual disability (ID): a condition characterized by significant limitations in intellectual functioning and adaptive behavior, which covers many everyday social and practical skills. This disorder used to be referred to as "mental retardation."
2. Communication disorders: these are disorders that affect an individual's ability to communicate, including language disorders, speech sound disorders, and stuttering.
3. Attention-deficit/hyperactivity disorder (ADHD): a neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity, and impulsivity.
4. Specific learning disorder: a neurodevelopmental disorder that affects an individual's ability to learn and use specific academic skills, such as reading, writing, or mathematics.
5. Motor disorders: these are disorders that affect an individual's movement and coordination, including developmental coordination disorder, stereotypic movement disorder, and tic disorders.

The medical definition of 'Child Development Disorders, Pervasive' has been replaced with more specific diagnoses in the DSM-5 to better reflect the diverse nature of these conditions and improve diagnostic accuracy and treatment planning.

A phobic disorder is a type of anxiety disorder characterized by an excessive and irrational fear or avoidance of specific objects, situations, or activities. This fear can cause significant distress and interfere with a person's daily life. Phobic disorders are typically classified into three main categories: specific phobias (such as fear of heights, spiders, or needles), social phobia (or social anxiety disorder), and agoraphobia (fear of open spaces or situations where escape might be difficult).

People with phobic disorders often recognize that their fear is excessive or unreasonable, but they are unable to control it. When exposed to the feared object or situation, they may experience symptoms such as rapid heartbeat, sweating, trembling, and difficulty breathing. These symptoms can be so distressing that individuals with phobic disorders go to great lengths to avoid the feared situation, which can have a significant impact on their quality of life.

Treatment for phobic disorders typically involves cognitive-behavioral therapy (CBT), which helps individuals identify and challenge their irrational thoughts and fears, as well as exposure therapy, which gradually exposes them to the feared object or situation in a safe and controlled environment. In some cases, medication may also be recommended to help manage symptoms of anxiety.

Cognitive disorders are a category of mental health disorders that primarily affect cognitive abilities including learning, memory, perception, and problem-solving. These disorders can be caused by various factors such as brain injury, degenerative diseases, infection, substance abuse, or developmental disabilities. Examples of cognitive disorders include dementia, amnesia, delirium, and intellectual disability. It's important to note that the specific definition and diagnostic criteria for cognitive disorders may vary depending on the medical source or classification system being used.

Psychotic disorders are a group of severe mental health conditions characterized by distorted perceptions, thoughts, and emotions that lead to an inability to recognize reality. The two most common symptoms of psychotic disorders are hallucinations and delusions. Hallucinations are when a person sees, hears, or feels things that aren't there, while delusions are fixed, false beliefs that are not based on reality.

Other symptoms may include disorganized speech, disorganized behavior, catatonic behavior, and negative symptoms such as apathy and lack of emotional expression. Schizophrenia is the most well-known psychotic disorder, but other types include schizoaffective disorder, delusional disorder, brief psychotic disorder, shared psychotic disorder, and substance-induced psychotic disorder.

Psychotic disorders can be caused by a variety of factors, including genetics, brain chemistry imbalances, trauma, and substance abuse. Treatment typically involves a combination of medication, therapy, and support services to help manage symptoms and improve quality of life.

Child development is a multidisciplinary field that examines the biological, psychological, emotional, and social growth and changes that occur in human beings between birth and the onset of adulthood. It involves a complex interaction of genetics, environment, culture, and experiences that shape a child's growth and development over time.

Child development is typically divided into several domains, including:

1. Physical Development: This refers to the growth and changes in a child's body, including their motor skills, sensory abilities, and overall health.
2. Cognitive Development: This involves the development of a child's thinking, learning, problem-solving, memory, language, and other mental processes.
3. Emotional Development: This refers to the development of a child's emotional awareness, expression, understanding, and regulation.
4. Social Development: This involves the development of a child's ability to interact with others, form relationships, communicate effectively, and understand social norms and expectations.

Child development is an ongoing process that occurs at different rates and in different ways for each child. Understanding typical patterns of child development can help parents, educators, and healthcare providers support children's growth and identify any potential delays or concerns.

Neuropsychological tests are a type of psychological assessment that measures cognitive functions, such as attention, memory, language, problem-solving, and perception. These tests are used to help diagnose and understand the cognitive impact of neurological conditions, including dementia, traumatic brain injury, stroke, Parkinson's disease, and other disorders that affect the brain.

The tests are typically administered by a trained neuropsychologist and can take several hours to complete. They may involve paper-and-pencil tasks, computerized tasks, or interactive activities. The results of the tests are compared to normative data to help identify any areas of cognitive weakness or strength.

Neuropsychological testing can provide valuable information for treatment planning, rehabilitation, and assessing response to treatment. It can also be used in research to better understand the neural basis of cognition and the impact of neurological conditions on cognitive function.

Analysis of Variance (ANOVA) is a statistical technique used to compare the means of two or more groups and determine whether there are any significant differences between them. It is a way to analyze the variance in a dataset to determine whether the variability between groups is greater than the variability within groups, which can indicate that the groups are significantly different from one another.

ANOVA is based on the concept of partitioning the total variance in a dataset into two components: variance due to differences between group means (also known as "between-group variance") and variance due to differences within each group (also known as "within-group variance"). By comparing these two sources of variance, ANOVA can help researchers determine whether any observed differences between groups are statistically significant, or whether they could have occurred by chance.

ANOVA is a widely used technique in many areas of research, including biology, psychology, engineering, and business. It is often used to compare the means of two or more experimental groups, such as a treatment group and a control group, to determine whether the treatment had a significant effect. ANOVA can also be used to compare the means of different populations or subgroups within a population, to identify any differences that may exist between them.

Serial learning is a form of learning in which new information or skills are acquired and organized in a sequential manner, with each piece of information building on the previous one. In other words, it involves learning items or concepts one at a time, in a specific order, rather than all at once. This type of learning is often used in situations where the material to be learned has a clear sequence, such as learning the alphabet, numbers, or days of the week.

In a medical context, serial learning may be used to teach complex medical procedures or concepts that have multiple steps or components. For example, a medical student may learn how to perform a physical examination by first learning how to take a patient's vital signs, then moving on to inspecting various parts of the body in a specific order. Through repeated practice and reinforcement, the student gradually builds up a sequence of skills and knowledge that becomes integrated into their long-term memory.

It is worth noting that some individuals may find serial learning more challenging than other forms of learning, particularly if they have difficulty with sequential processing or working memory limitations. Therefore, individualized instruction and accommodations may be necessary to support learners who struggle with serial learning tasks.

A mutation is a permanent change in the DNA sequence of an organism's genome. Mutations can occur spontaneously or be caused by environmental factors such as exposure to radiation, chemicals, or viruses. They may have various effects on the organism, ranging from benign to harmful, depending on where they occur and whether they alter the function of essential proteins. In some cases, mutations can increase an individual's susceptibility to certain diseases or disorders, while in others, they may confer a survival advantage. Mutations are the driving force behind evolution, as they introduce new genetic variability into populations, which can then be acted upon by natural selection.

'Task Performance and Analysis' is not a commonly used medical term, but it can be found in the field of rehabilitation medicine and ergonomics. It refers to the process of evaluating and understanding how a specific task is performed, in order to identify any physical or cognitive demands placed on an individual during the performance of that task. This information can then be used to inform the design of interventions, such as workplace modifications or rehabilitation programs, aimed at improving task performance or reducing the risk of injury.

In a medical context, task performance and analysis may be used in the assessment and treatment of individuals with disabilities or injuries, to help them return to work or other activities of daily living. The analysis involves breaking down the task into its component parts, observing and measuring the physical and cognitive demands of each part, and evaluating the individual's ability to perform those demands. Based on this analysis, recommendations may be made for modifications to the task or the environment, training or education, or assistive devices that can help the individual perform the task more safely and efficiently.

Overall, task performance and analysis is a valuable tool in promoting safe and effective task performance, reducing the risk of injury, and improving functional outcomes for individuals with disabilities or injuries.

Functional laterality, in a medical context, refers to the preferential use or performance of one side of the body over the other for specific functions. This is often demonstrated in hand dominance, where an individual may be right-handed or left-handed, meaning they primarily use their right or left hand for tasks such as writing, eating, or throwing.

However, functional laterality can also apply to other bodily functions and structures, including the eyes (ocular dominance), ears (auditory dominance), or legs. It's important to note that functional laterality is not a strict binary concept; some individuals may exhibit mixed dominance or no strong preference for one side over the other.

In clinical settings, assessing functional laterality can be useful in diagnosing and treating various neurological conditions, such as stroke or traumatic brain injury, where understanding any resulting lateralized impairments can inform rehabilitation strategies.

Neuronal plasticity, also known as neuroplasticity or neural plasticity, refers to the ability of the brain and nervous system to change and adapt as a result of experience, learning, injury, or disease. This can involve changes in the structure, organization, and function of neurons (nerve cells) and their connections (synapses) in the central and peripheral nervous systems.

Neuronal plasticity can take many forms, including:

* Synaptic plasticity: Changes in the strength or efficiency of synaptic connections between neurons. This can involve the formation, elimination, or modification of synapses.
* Neural circuit plasticity: Changes in the organization and connectivity of neural circuits, which are networks of interconnected neurons that process information.
* Structural plasticity: Changes in the physical structure of neurons, such as the growth or retraction of dendrites (branches that receive input from other neurons) or axons (projections that transmit signals to other neurons).
* Functional plasticity: Changes in the physiological properties of neurons, such as their excitability, responsiveness, or sensitivity to stimuli.

Neuronal plasticity is a fundamental property of the nervous system and plays a crucial role in many aspects of brain function, including learning, memory, perception, and cognition. It also contributes to the brain's ability to recover from injury or disease, such as stroke or traumatic brain injury.

Conduct Disorder is a mental health disorder that typically begins in childhood or adolescence and is characterized by a repetitive pattern of behavior that violates the rights of others or major age-appropriate societal norms and rules. The behaviors fall into four main categories: aggression to people and animals, destruction of property, deceitfulness or theft, and serious violation of rules.

The specific symptoms of Conduct Disorder can vary widely among individuals, but they generally include:

1. Aggression to people and animals: This may include physical fights, bullying, threatening others, cruelty to animals, and use of weapons.
2. Destruction of property: This may include deliberate destruction of others' property, arson, and vandalism.
3. Deceitfulness or theft: This may include lying, shoplifting, stealing, and breaking into homes, buildings, or cars.
4. Serious violation of rules: This may include running away from home, truancy, staying out late without permission, and frequent violations of school rules.

Conduct Disorder can have serious consequences for individuals who suffer from it, including academic failure, substance abuse, depression, anxiety, and difficulties in interpersonal relationships. It is important to note that Conduct Disorder should be diagnosed by a qualified mental health professional based on a comprehensive evaluation.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

Psychomotor disorders are conditions that involve abnormalities in cognition, emotion, and behavior associated with impaired voluntary motor or movement functions. These disorders can be characterized by hypoactivity (decreased motor activity) or hyperactivity (increased motor activity). Examples of psychomotor disorders include Parkinson's disease, Huntington's disease, Tourette syndrome, and catatonia. Psychomotor agitation, retardation, and stereotypies are also considered psychomotor disorders. These conditions can significantly impact a person's daily functioning and quality of life.

Animal disease models are specialized animals, typically rodents such as mice or rats, that have been genetically engineered or exposed to certain conditions to develop symptoms and physiological changes similar to those seen in human diseases. These models are used in medical research to study the pathophysiology of diseases, identify potential therapeutic targets, test drug efficacy and safety, and understand disease mechanisms.

The genetic modifications can include knockout or knock-in mutations, transgenic expression of specific genes, or RNA interference techniques. The animals may also be exposed to environmental factors such as chemicals, radiation, or infectious agents to induce the disease state.

Examples of animal disease models include:

1. Mouse models of cancer: Genetically engineered mice that develop various types of tumors, allowing researchers to study cancer initiation, progression, and metastasis.
2. Alzheimer's disease models: Transgenic mice expressing mutant human genes associated with Alzheimer's disease, which exhibit amyloid plaque formation and cognitive decline.
3. Diabetes models: Obese and diabetic mouse strains like the NOD (non-obese diabetic) or db/db mice, used to study the development of type 1 and type 2 diabetes, respectively.
4. Cardiovascular disease models: Atherosclerosis-prone mice, such as ApoE-deficient or LDLR-deficient mice, that develop plaque buildup in their arteries when fed a high-fat diet.
5. Inflammatory bowel disease models: Mice with genetic mutations affecting intestinal barrier function and immune response, such as IL-10 knockout or SAMP1/YitFc mice, which develop colitis.

Animal disease models are essential tools in preclinical research, but it is important to recognize their limitations. Differences between species can affect the translatability of results from animal studies to human patients. Therefore, researchers must carefully consider the choice of model and interpret findings cautiously when applying them to human diseases.

Psychiatric Status Rating Scales are standardized assessment tools used by mental health professionals to evaluate and rate the severity of a person's psychiatric symptoms and functioning. These scales provide a systematic and structured approach to measuring various aspects of an individual's mental health, such as mood, anxiety, psychosis, behavior, and cognitive abilities.

The purpose of using Psychiatric Status Rating Scales is to:

1. Assess the severity and improvement of psychiatric symptoms over time.
2. Aid in diagnostic decision-making and treatment planning.
3. Monitor treatment response and adjust interventions accordingly.
4. Facilitate communication among mental health professionals about a patient's status.
5. Provide an objective basis for research and epidemiological studies.

Examples of Psychiatric Status Rating Scales include:

1. Clinical Global Impression (CGI): A brief, subjective rating scale that measures overall illness severity, treatment response, and improvement.
2. Positive and Negative Syndrome Scale (PANSS): A comprehensive scale used to assess the symptoms of psychosis, including positive, negative, and general psychopathology domains.
3. Hamilton Rating Scale for Depression (HRSD) or Montgomery-Åsberg Depression Rating Scale (MADRS): Scales used to evaluate the severity of depressive symptoms.
4. Young Mania Rating Scale (YMRS): A scale used to assess the severity of manic or hypomanic symptoms.
5. Brief Psychiatric Rating Scale (BPRS) or Symptom Checklist-90 Revised (SCL-90-R): Scales that measure a broad range of psychiatric symptoms and psychopathology.
6. Global Assessment of Functioning (GAF): A scale used to rate an individual's overall psychological, social, and occupational functioning on a hypothetical continuum of mental health-illness.

It is important to note that Psychiatric Status Rating Scales should be administered by trained mental health professionals to ensure accurate and reliable results.

Cognition refers to the mental processes involved in acquiring, processing, and utilizing information. These processes include perception, attention, memory, language, problem-solving, and decision-making. Cognitive functions allow us to interact with our environment, understand and respond to stimuli, learn new skills, and remember experiences.

In a medical context, cognitive function is often assessed as part of a neurological or psychiatric evaluation. Impairments in cognition can be caused by various factors, such as brain injury, neurodegenerative diseases (e.g., Alzheimer's disease), infections, toxins, and mental health conditions. Assessing cognitive function helps healthcare professionals diagnose conditions, monitor disease progression, and develop treatment plans.

The Rotarod performance test is not a medical diagnosis or condition, but rather a laboratory test used in both preclinical research and clinical settings to evaluate various aspects of motor function and balance in animals, including mice and rats. The test is often used to assess the neurological status, sensorimotor function, and coordination abilities of animals following drug treatments, surgical interventions, or in models of neurodegenerative diseases.

In this test, a rodent is placed on a rotating rod with a diameter that allows the animal to comfortably grip it. The rotation speed gradually increases over time, and the researcher records how long the animal can maintain its balance and stay on the rod without falling off. This duration is referred to as the "latency to fall" or "rotarod performance."

The Rotarod performance test offers several advantages, such as its sensitivity to various neurological impairments, ease of use, and ability to provide quantitative data for statistical analysis. It can help researchers evaluate potential therapeutic interventions, monitor disease progression, and investigate the underlying mechanisms of motor function and balance in health and disease.

A phenotype is the physical or biochemical expression of an organism's genes, or the observable traits and characteristics resulting from the interaction of its genetic constitution (genotype) with environmental factors. These characteristics can include appearance, development, behavior, and resistance to disease, among others. Phenotypes can vary widely, even among individuals with identical genotypes, due to differences in environmental influences, gene expression, and genetic interactions.

In the context of medical and clinical neuroscience, memory is defined as the brain's ability to encode, store, retain, and recall information or experiences. Memory is a complex cognitive process that involves several interconnected regions of the brain and can be categorized into different types based on various factors such as duration and the nature of the information being remembered.

The major types of memory include:

1. Sensory memory: The shortest form of memory, responsible for holding incoming sensory information for a brief period (less than a second to several seconds) before it is either transferred to short-term memory or discarded.
2. Short-term memory (also called working memory): A temporary storage system that allows the brain to hold and manipulate information for approximately 20-30 seconds, although this duration can be extended through rehearsal strategies. Short-term memory has a limited capacity, typically thought to be around 7±2 items.
3. Long-term memory: The memory system responsible for storing large amounts of information over extended periods, ranging from minutes to a lifetime. Long-term memory has a much larger capacity compared to short-term memory and is divided into two main categories: explicit (declarative) memory and implicit (non-declarative) memory.

Explicit (declarative) memory can be further divided into episodic memory, which involves the recollection of specific events or episodes, including their temporal and spatial contexts, and semantic memory, which refers to the storage and retrieval of general knowledge, facts, concepts, and vocabulary, independent of personal experience or context.

Implicit (non-declarative) memory encompasses various forms of learning that do not require conscious awareness or intention, such as procedural memory (skills and habits), priming (facilitated processing of related stimuli), classical conditioning (associative learning), and habituation (reduced responsiveness to repeated stimuli).

Memory is a crucial aspect of human cognition and plays a significant role in various aspects of daily life, including learning, problem-solving, decision-making, social interactions, and personal identity. Memory dysfunction can result from various neurological and psychiatric conditions, such as dementia, Alzheimer's disease, stroke, traumatic brain injury, and depression.

Tic disorders are a group of conditions characterized by the presence of repetitive, involuntary movements or sounds, known as tics. These movements or sounds can vary in complexity and severity, and they may be worsened by stress or strong emotions.

There are several different types of tic disorders, including:

1. Tourette's disorder: This is a neurological condition characterized by the presence of both motor (movement-related) and vocal tics that have been present for at least one year. The tics may wax and wane in severity over time, but they do not disappear for more than three consecutive months.
2. Persistent (chronic) motor or vocal tic disorder: This type of tic disorder is characterized by the presence of either motor or vocal tics (but not both), which have been present for at least one year. The tics may wax and wane in severity over time, but they do not disappear for more than three consecutive months.
3. Provisional tic disorder: This type of tic disorder is characterized by the presence of motor or vocal tics (or both) that have been present for less than one year. The tics may wax and wane in severity over time, but they do not disappear for more than three consecutive months.
4. Tic disorder not otherwise specified: This category is used to describe tic disorders that do not meet the criteria for any of the other types of tic disorders.

Tic disorders are thought to be caused by a combination of genetic and environmental factors, and they often co-occur with other conditions such as attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). Treatment for tic disorders may include behavioral therapy, medication, or a combination of both.

A forelimb is a term used in animal anatomy to refer to the upper limbs located in the front of the body, primarily involved in movement and manipulation of the environment. In humans, this would be equivalent to the arms, while in quadrupedal animals (those that move on four legs), it includes the structures that are comparable to both the arms and legs of humans, such as the front legs of dogs or the forepaws of cats. The bones that make up a typical forelimb include the humerus, radius, ulna, carpals, metacarpals, and phalanges.

Molecular motor proteins are a type of protein that convert chemical energy into mechanical work at the molecular level. They play a crucial role in various cellular processes, such as cell division, muscle contraction, and intracellular transport. There are several types of molecular motor proteins, including myosin, kinesin, and dynein.

Myosin is responsible for muscle contraction and movement along actin filaments in the cytoplasm. Kinesin and dynein are involved in intracellular transport along microtubules, moving cargo such as vesicles, organelles, and mRNA to various destinations within the cell.

These motor proteins move in a stepwise fashion, with each step driven by the hydrolysis of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and inorganic phosphate (Pi). The directionality and speed of movement are determined by the structure and regulation of the motor proteins, as well as the properties of the tracks along which they move.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Reaction time, in the context of medicine and physiology, refers to the time period between the presentation of a stimulus and the subsequent initiation of a response. This complex process involves the central nervous system, particularly the brain, which perceives the stimulus, processes it, and then sends signals to the appropriate muscles or glands to react.

There are different types of reaction times, including simple reaction time (responding to a single, expected stimulus) and choice reaction time (choosing an appropriate response from multiple possibilities). These measures can be used in clinical settings to assess various aspects of neurological function, such as cognitive processing speed, motor control, and alertness.

However, it is important to note that reaction times can be influenced by several factors, including age, fatigue, attention, and the use of certain medications or substances.

Brain mapping is a broad term that refers to the techniques used to understand the structure and function of the brain. It involves creating maps of the various cognitive, emotional, and behavioral processes in the brain by correlating these processes with physical locations or activities within the nervous system. Brain mapping can be accomplished through a variety of methods, including functional magnetic resonance imaging (fMRI), positron emission tomography (PET) scans, electroencephalography (EEG), and others. These techniques allow researchers to observe which areas of the brain are active during different tasks or thoughts, helping to shed light on how the brain processes information and contributes to our experiences and behaviors. Brain mapping is an important area of research in neuroscience, with potential applications in the diagnosis and treatment of neurological and psychiatric disorders.

Borderline Personality Disorder (BPD) is a mental health disorder characterized by a pervasive pattern of instability in interpersonal relationships, self-image, affect, and mood, as well as marked impulsivity that begins by early adulthood and is present in various contexts.

Individuals with BPD often experience intense and fluctuating emotions, ranging from profound sadness, anxiety, and anger to feelings of happiness or calm. They may have difficulty managing these emotions, leading to impulsive behavior, self-harm, or suicidal ideation.

People with BPD also tend to have an unstable sense of self, which can lead to rapid changes in their goals, values, and career choices. They often struggle with feelings of emptiness and boredom, and may engage in risky behaviors such as substance abuse, reckless driving, or binge eating to alleviate these feelings.

Interpersonal relationships are often strained due to the individual's fear of abandonment, intense emotional reactions, and difficulty regulating their emotions. They may experience idealization and devaluation of others, leading to rapid shifts in how they view and treat people close to them.

Diagnosis of BPD is typically made by a mental health professional using criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), which is published by the American Psychiatric Association. Treatment for BPD may include psychotherapy, medication, and support groups to help individuals manage their symptoms and improve their quality of life.

A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.

For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.

It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.

In medical terms, a hand is the part of the human body that is attached to the forearm and consists of the carpus (wrist), metacarpus, and phalanges. It is made up of 27 bones, along with muscles, tendons, ligaments, and other soft tissues. The hand is a highly specialized organ that is capable of performing a wide range of complex movements and functions, including grasping, holding, manipulating objects, and communicating through gestures. It is also richly innervated with sensory receptors that provide information about touch, temperature, pain, and proprioception (the sense of the position and movement of body parts).

I must clarify that the term "pedigree" is not typically used in medical definitions. Instead, it is often employed in genetics and breeding, where it refers to the recorded ancestry of an individual or a family, tracing the inheritance of specific traits or diseases. In human genetics, a pedigree can help illustrate the pattern of genetic inheritance in families over multiple generations. However, it is not a medical term with a specific clinical definition.

Sleep disorders are a group of conditions that affect the ability to sleep well on a regular basis. They can include problems with falling asleep, staying asleep, or waking up too early in the morning. These disorders can be caused by various factors such as stress, anxiety, depression, medical conditions, or substance abuse.

The American Academy of Sleep Medicine (AASM) recognizes over 80 distinct sleep disorders, which are categorized into the following major groups:

1. Insomnia - difficulty falling asleep or staying asleep.
2. Sleep-related breathing disorders - abnormal breathing during sleep such as obstructive sleep apnea.
3. Central disorders of hypersomnolence - excessive daytime sleepiness, including narcolepsy.
4. Circadian rhythm sleep-wake disorders - disruption of the internal body clock that regulates the sleep-wake cycle.
5. Parasomnias - abnormal behaviors during sleep such as sleepwalking or night terrors.
6. Sleep-related movement disorders - repetitive movements during sleep such as restless legs syndrome.
7. Isolated symptoms and normal variants - brief and occasional symptoms that do not warrant a specific diagnosis.

Sleep disorders can have significant impacts on an individual's quality of life, productivity, and overall health. If you suspect that you may have a sleep disorder, it is recommended to consult with a healthcare professional or a sleep specialist for proper evaluation and treatment.

Somatoform disorders are a group of psychological disorders characterized by the presence of physical symptoms that cannot be fully explained by a medical condition or substance abuse. These symptoms cause significant distress and impairment in social, occupational, or other important areas of functioning. The individual's belief about the symptoms is not consistent with the medical evaluation and often leads to excessive or repeated medical evaluations.

Examples of somatoform disorders include:

1. Somatization disorder: characterized by multiple physical symptoms that cannot be explained medically, affecting several parts of the body.
2. Conversion disorder: characterized by the presence of one or more neurological symptoms (such as blindness, paralysis, or difficulty swallowing) that cannot be explained medically and appear to have a psychological origin.
3. Pain disorder: characterized by chronic pain that is not fully explained by a medical condition.
4. Hypochondriasis: characterized by an excessive preoccupation with having a serious illness, despite reassurance from medical professionals.
5. Body dysmorphic disorder: characterized by the obsessive idea that some aspect of one's own body part or appearance is severely flawed and warrants exceptional measures to hide or fix it.

It's important to note that these disorders are not caused by intentional deceit or malingering, but rather reflect a genuine belief in the presence of physical symptoms and distress related to them.

Transcranial Magnetic Stimulation (TMS) is a non-invasive form of brain stimulation where a magnetic field is generated via an electromagnetic coil placed on the scalp. This magnetic field induces an electric current in the underlying brain tissue, which can lead to neuronal activation or inhibition, depending on the frequency and intensity of the stimulation. TMS has been used as a therapeutic intervention for various neurological and psychiatric conditions, such as depression, migraine, and tinnitus, among others. It is also used in research settings to investigate brain function and connectivity.

Language development disorders, also known as language impairments or communication disorders, refer to a group of conditions that affect an individual's ability to understand and/or use spoken or written language in a typical manner. These disorders can manifest as difficulties with grammar, vocabulary, sentence structure, word finding, following directions, and/or conversational skills.

Language development disorders can be receptive (difficulty understanding language), expressive (difficulty using language to communicate), or mixed (a combination of both). They can occur in isolation or as part of a broader neurodevelopmental disorder, such as autism spectrum disorder or intellectual disability.

The causes of language development disorders are varied and may include genetic factors, environmental influences, neurological conditions, hearing loss, or other medical conditions. It is important to note that language development disorders are not the result of low intelligence or lack of motivation; rather, they reflect a specific impairment in the brain's language processing systems.

Early identification and intervention for language development disorders can significantly improve outcomes and help individuals develop effective communication skills. Treatment typically involves speech-language therapy, which may be provided individually or in a group setting, and may involve strategies such as modeling correct language use, practicing targeted language skills, and using visual aids to support comprehension.

A Severity of Illness Index is a measurement tool used in healthcare to assess the severity of a patient's condition and the risk of mortality or other adverse outcomes. These indices typically take into account various physiological and clinical variables, such as vital signs, laboratory values, and co-morbidities, to generate a score that reflects the patient's overall illness severity.

Examples of Severity of Illness Indices include the Acute Physiology and Chronic Health Evaluation (APACHE) system, the Simplified Acute Physiology Score (SAPS), and the Mortality Probability Model (MPM). These indices are often used in critical care settings to guide clinical decision-making, inform prognosis, and compare outcomes across different patient populations.

It is important to note that while these indices can provide valuable information about a patient's condition, they should not be used as the sole basis for clinical decision-making. Rather, they should be considered in conjunction with other factors, such as the patient's overall clinical presentation, treatment preferences, and goals of care.

A case-control study is an observational research design used to identify risk factors or causes of a disease or health outcome. In this type of study, individuals with the disease or condition (cases) are compared with similar individuals who do not have the disease or condition (controls). The exposure history or other characteristics of interest are then compared between the two groups to determine if there is an association between the exposure and the disease.

Case-control studies are often used when it is not feasible or ethical to conduct a randomized controlled trial, as they can provide valuable insights into potential causes of diseases or health outcomes in a relatively short period of time and at a lower cost than other study designs. However, because case-control studies rely on retrospective data collection, they are subject to biases such as recall bias and selection bias, which can affect the validity of the results. Therefore, it is important to carefully design and conduct case-control studies to minimize these potential sources of bias.

Electromyography (EMG) is a medical diagnostic procedure that measures the electrical activity of skeletal muscles during contraction and at rest. It involves inserting a thin needle electrode into the muscle to record the electrical signals generated by the muscle fibers. These signals are then displayed on an oscilloscope and may be heard through a speaker.

EMG can help diagnose various neuromuscular disorders, such as muscle weakness, numbness, or pain, and can distinguish between muscle and nerve disorders. It is often used in conjunction with other diagnostic tests, such as nerve conduction studies, to provide a comprehensive evaluation of the nervous system.

EMG is typically performed by a neurologist or a physiatrist, and the procedure may cause some discomfort or pain, although this is usually minimal. The results of an EMG can help guide treatment decisions and monitor the progression of neuromuscular conditions over time.

Comorbidity is the presence of one or more additional health conditions or diseases alongside a primary illness or condition. These co-occurring health issues can have an impact on the treatment plan, prognosis, and overall healthcare management of an individual. Comorbidities often interact with each other and the primary condition, leading to more complex clinical situations and increased healthcare needs. It is essential for healthcare professionals to consider and address comorbidities to provide comprehensive care and improve patient outcomes.

A questionnaire in the medical context is a standardized, systematic, and structured tool used to gather information from individuals regarding their symptoms, medical history, lifestyle, or other health-related factors. It typically consists of a series of written questions that can be either self-administered or administered by an interviewer. Questionnaires are widely used in various areas of healthcare, including clinical research, epidemiological studies, patient care, and health services evaluation to collect data that can inform diagnosis, treatment planning, and population health management. They provide a consistent and organized method for obtaining information from large groups or individual patients, helping to ensure accurate and comprehensive data collection while minimizing bias and variability in the information gathered.

In medical terms, fingers are not specifically defined as they are common anatomical structures. However, I can provide you with a general anatomy definition:

Fingers are the terminal parts of the upper limb in primates, including humans, consisting of four digits (thumb, index, middle, and ring fingers) and one opposable thumb. They contain bones called phalanges, connected by joints that allow for movement and flexibility. Each finger has a nail, nerve endings for sensation, and blood vessels to supply nutrients and oxygen. Fingers are crucial for various activities such as grasping, manipulating objects, and tactile exploration of the environment.

Neurons, also known as nerve cells or neurocytes, are specialized cells that constitute the basic unit of the nervous system. They are responsible for receiving, processing, and transmitting information and signals within the body. Neurons have three main parts: the dendrites, the cell body (soma), and the axon. The dendrites receive signals from other neurons or sensory receptors, while the axon transmits these signals to other neurons, muscles, or glands. The junction between two neurons is called a synapse, where neurotransmitters are released to transmit the signal across the gap (synaptic cleft) to the next neuron. Neurons vary in size, shape, and structure depending on their function and location within the nervous system.

Speech disorders refer to a group of conditions in which a person has difficulty producing or articulating sounds, words, or sentences in a way that is understandable to others. These disorders can be caused by various factors such as developmental delays, neurological conditions, hearing loss, structural abnormalities, or emotional issues.

Speech disorders may include difficulties with:

* Articulation: the ability to produce sounds correctly and clearly.
* Phonology: the sound system of language, including the rules that govern how sounds are combined and used in words.
* Fluency: the smoothness and flow of speech, including issues such as stuttering or cluttering.
* Voice: the quality, pitch, and volume of the spoken voice.
* Resonance: the way sound is produced and carried through the vocal tract, which can affect the clarity and quality of speech.

Speech disorders can impact a person's ability to communicate effectively, leading to difficulties in social situations, academic performance, and even employment opportunities. Speech-language pathologists are trained to evaluate and treat speech disorders using various evidence-based techniques and interventions.

Schizophrenia is a severe mental disorder characterized by disturbances in thought, perception, emotion, and behavior. It often includes hallucinations (usually hearing voices), delusions, paranoia, and disorganized speech and behavior. The onset of symptoms typically occurs in late adolescence or early adulthood. Schizophrenia is a complex, chronic condition that requires ongoing treatment and management. It significantly impairs social and occupational functioning, and it's often associated with reduced life expectancy due to comorbid medical conditions. The exact causes of schizophrenia are not fully understood, but research suggests that genetic, environmental, and neurodevelopmental factors play a role in its development.

Language development refers to the process by which children acquire the ability to understand and communicate through spoken, written, or signed language. This complex process involves various components including phonology (sound system), semantics (meaning of words and sentences), syntax (sentence structure), and pragmatics (social use of language). Language development begins in infancy with cooing and babbling and continues through early childhood and beyond, with most children developing basic conversational skills by the age of 4-5 years. However, language development can continue into adolescence and even adulthood as individuals learn new languages or acquire more advanced linguistic skills. Factors that can influence language development include genetics, environment, cognition, and social interactions.

Lymphoproliferative disorders (LPDs) are a group of diseases characterized by the excessive proliferation of lymphoid cells, which are crucial components of the immune system. These disorders can arise from both B-cells and T-cells, leading to various clinical manifestations ranging from benign to malignant conditions.

LPDs can be broadly classified into reactive and neoplastic categories:

1. Reactive Lymphoproliferative Disorders: These are typically triggered by infections, autoimmune diseases, or immunodeficiency states. They involve an exaggerated response of the immune system leading to the excessive proliferation of lymphoid cells. Examples include:
* Infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV)
* Lymph node enlargement due to various infections or autoimmune disorders
* Post-transplant lymphoproliferative disorder (PTLD), which occurs in the context of immunosuppression following organ transplantation
2. Neoplastic Lymphoproliferative Disorders: These are malignant conditions characterized by uncontrolled growth and accumulation of abnormal lymphoid cells, leading to the formation of tumors. They can be further classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL). Examples include:
* Hodgkin lymphoma (HL): Classical HL and nodular lymphocyte-predominant HL
* Non-Hodgkin lymphoma (NHL): Various subtypes, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and Burkitt lymphoma

It is important to note that the distinction between reactive and neoplastic LPDs can sometimes be challenging, requiring careful clinical, histopathological, immunophenotypic, and molecular evaluations. Proper diagnosis and classification of LPDs are crucial for determining appropriate treatment strategies and predicting patient outcomes.

"Age factors" refer to the effects, changes, or differences that age can have on various aspects of health, disease, and medical care. These factors can encompass a wide range of issues, including:

1. Physiological changes: As people age, their bodies undergo numerous physical changes that can affect how they respond to medications, illnesses, and medical procedures. For example, older adults may be more sensitive to certain drugs or have weaker immune systems, making them more susceptible to infections.
2. Chronic conditions: Age is a significant risk factor for many chronic diseases, such as heart disease, diabetes, cancer, and arthritis. As a result, age-related medical issues are common and can impact treatment decisions and outcomes.
3. Cognitive decline: Aging can also lead to cognitive changes, including memory loss and decreased decision-making abilities. These changes can affect a person's ability to understand and comply with medical instructions, leading to potential complications in their care.
4. Functional limitations: Older adults may experience physical limitations that impact their mobility, strength, and balance, increasing the risk of falls and other injuries. These limitations can also make it more challenging for them to perform daily activities, such as bathing, dressing, or cooking.
5. Social determinants: Age-related factors, such as social isolation, poverty, and lack of access to transportation, can impact a person's ability to obtain necessary medical care and affect their overall health outcomes.

Understanding age factors is critical for healthcare providers to deliver high-quality, patient-centered care that addresses the unique needs and challenges of older adults. By taking these factors into account, healthcare providers can develop personalized treatment plans that consider a person's age, physical condition, cognitive abilities, and social circumstances.

Apraxia is a motor disorder characterized by the inability to perform learned, purposeful movements despite having the physical ability and mental understanding to do so. It is not caused by weakness, paralysis, or sensory loss, and it is not due to poor comprehension or motivation.

There are several types of apraxias, including:

1. Limb-Kinematic Apraxia: This type affects the ability to make precise movements with the limbs, such as using tools or performing complex gestures.
2. Ideomotor Apraxia: In this form, individuals have difficulty executing learned motor actions in response to verbal commands or visual cues, but they can still perform the same action when given the actual object to use.
3. Ideational Apraxia: This type affects the ability to sequence and coordinate multiple steps of a complex action, such as dressing oneself or making coffee.
4. Oral Apraxia: Also known as verbal apraxia, this form affects the ability to plan and execute speech movements, leading to difficulties with articulation and speech production.
5. Constructional Apraxia: This type impairs the ability to draw, copy, or construct geometric forms and shapes, often due to visuospatial processing issues.

Apraxias can result from various neurological conditions, such as stroke, brain injury, dementia, or neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. Treatment typically involves rehabilitation and therapy focused on retraining the affected movements and compensating for any residual deficits.

Attention Deficit and Disruptive Behavior Disorders (ADDBDs) are a group of childhood-onset disorders characterized by persistent patterns of behavior that are difficult for the individual to control. These disorders include Attention Deficit Hyperactivity Disorder (ADHD), Oppositional Defiant Disorder (ODD), and Conduct Disorder (CD).

Attention Deficit Hyperactivity Disorder (ADHD) is characterized by symptoms of inattention, hyperactivity, and impulsivity that interfere with daily functioning. These symptoms must be present for at least six months and occur in multiple settings, such as school, home, and social situations.

Oppositional Defiant Disorder (ODD) is characterized by a pattern of negative, hostile, and defiant behavior towards authority figures, which includes arguing with adults, losing temper, actively defying rules, and deliberately annoying others. These symptoms must be present for at least six months and occur more frequently than in other children of the same age and developmental level.

Conduct Disorder (CD) is characterized by a repetitive and persistent pattern of behavior that violates the rights of others or major age-appropriate societal norms and rules. These behaviors include aggression towards people and animals, destruction of property, deceitfulness or theft, and serious violation of rules.

It's important to note that these disorders can co-occur with other mental health conditions, such as mood disorders, anxiety disorders, and learning disabilities. Proper diagnosis and treatment are essential for managing the symptoms and improving the individual's quality of life.

Williams Syndrome is a rare genetic disorder caused by the deletion of a small portion of chromosome 7. This results in various developmental and medical problems, which can include:

1. Distinctive facial features such as a broad forehead, wide-set eyes, short nose, and full lips.
2. Cardiovascular disease, particularly narrowed or missing blood vessels near the heart.
3. Developmental delays and learning disabilities, although most people with Williams Syndrome have an IQ in the mild to moderate range of intellectual disability.
4. A unique pattern of strengths and weaknesses in cognitive skills, such as strong language skills but significant difficulty with visual-spatial tasks.
5. Overly friendly or sociable personality, often displaying a lack of fear or wariness around strangers.
6. Increased risk of anxiety and depression.
7. Sensitive hearing and poor depth perception.
8. Short stature in adulthood.

Williams Syndrome affects about 1 in every 10,000 people worldwide, regardless of race or ethnic background. It is not an inherited disorder, but rather a spontaneous genetic mutation.

According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), alcohol-related disorders are a category of mental disorders defined by a problematic pattern of alcohol use that leads to clinically significant impairment or distress. The disorders include:

1. Alcohol Use Disorder (AUD): A chronic relapsing brain disorder characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences. AUD can be mild, moderate, or severe, and recovery is possible regardless of severity. The symptoms include problems controlling intake of alcohol, continued use despite problems resulting from drinking, development of a tolerance, drinking that leads to risky situations, or withdrawal symptoms when not drinking.
2. Alcohol Intoxication: A state of acute impairment in mental and motor function caused by the recent consumption of alcohol. The symptoms include slurred speech, unsteady gait, nystagmus, impaired attention or memory, stupor, or coma. In severe cases, it can lead to respiratory depression, hypothermia, or even death.
3. Alcohol Withdrawal: A syndrome that occurs when alcohol use is heavily reduced or stopped after prolonged and heavy use. The symptoms include autonomic hyperactivity, increased hand tremor, insomnia, nausea or vomiting, transient visual, tactile, or auditory hallucinations or illusions, psychomotor agitation, anxiety, and grand mal seizures.
4. Other Alcohol-Induced Disorders: These include alcohol-induced sleep disorder, alcohol-induced sexual dysfunction, and alcohol-induced major neurocognitive disorder.

It is important to note that alcohol use disorders are complex conditions that can be influenced by a variety of factors, including genetics, environment, and personal behavior. If you or someone you know is struggling with alcohol use, it is recommended to seek professional help.

Inborn errors of metabolism (IEM) refer to a group of genetic disorders caused by defects in enzymes or transporters that play a role in the body's metabolic processes. These disorders result in the accumulation or deficiency of specific chemicals within the body, which can lead to various clinical manifestations, such as developmental delay, intellectual disability, seizures, organ damage, and in some cases, death.

Examples of IEM include phenylketonuria (PKU), maple syrup urine disease (MSUD), galactosemia, and glycogen storage diseases, among many others. These disorders are typically inherited in an autosomal recessive manner, meaning that an affected individual has two copies of the mutated gene, one from each parent.

Early diagnosis and management of IEM are crucial to prevent or minimize complications and improve outcomes. Treatment options may include dietary modifications, supplementation with missing enzymes or cofactors, medication, and in some cases, stem cell transplantation or gene therapy.

Child behavior refers to the actions, reactions, and interactions exhibited by children in response to their environment, experiences, and developmental stage. It is a broad term that encompasses various aspects, including emotional, social, cognitive, and physical development.

Child behavior can be categorized into two main types:

1. Desirable or positive behaviors - These are behaviors that promote healthy development, social interactions, and learning. Examples include sharing toys, following rules, expressing emotions appropriately, and demonstrating empathy towards others.
2. Challenging or negative behaviors - These are behaviors that hinder healthy development, social interactions, and learning. Examples include aggression, defiance, tantrums, anxiety, and withdrawal.

Understanding child behavior is crucial for parents, caregivers, educators, and healthcare professionals to provide appropriate support, guidance, and interventions to promote positive developmental outcomes in children. Factors influencing child behavior include genetics, temperament, environment, parenting style, and life experiences.

Impulse Control Disorders (ICDs) are a group of psychiatric conditions characterized by the failure to resist an impulse, drive, or temptation to perform an act that is harmful to oneself or others. This leads to negative consequences such as distress, anxiety, or disruption in social, occupational, or other important areas of functioning.

The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) recognizes several specific ICDs, including:

1. Kleptomania - the recurrent failure to resist impulses to steal items, even though they are not needed for personal use or financial gain.
2. Pyromania - the deliberate and purposeful fire-setting on more than one occasion.
3. Intermittent Explosive Disorder - recurrent behavioral outbursts representing a failure to control aggressive impulses, resulting in serious assaultive acts or destruction of property.
4. Pathological Gambling - persistent and recurrent maladaptive gambling behavior that disrupts personal, family, or vocational pursuits.
5. Internet Gaming Disorder - the excessive and prolonged use of the internet for gaming, which leads to clinically significant impairment or distress.

These disorders are typically associated with a range of emotional, cognitive, and behavioral symptoms that can vary depending on the specific disorder and individual presentation. Treatment often involves a combination of psychotherapy, medication, and self-help strategies to manage symptoms and improve overall functioning.

Nervous system diseases, also known as neurological disorders, refer to a group of conditions that affect the nervous system, which includes the brain, spinal cord, nerves, and muscles. These diseases can affect various functions of the body, such as movement, sensation, cognition, and behavior. They can be caused by genetics, infections, injuries, degeneration, or tumors. Examples of nervous system diseases include Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, migraine, stroke, and neuroinfections like meningitis and encephalitis. The symptoms and severity of these disorders can vary widely, ranging from mild to severe and debilitating.

Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.

Medical Definition:

"Risk factors" are any attribute, characteristic or exposure of an individual that increases the likelihood of developing a disease or injury. They can be divided into modifiable and non-modifiable risk factors. Modifiable risk factors are those that can be changed through lifestyle choices or medical treatment, while non-modifiable risk factors are inherent traits such as age, gender, or genetic predisposition. Examples of modifiable risk factors include smoking, alcohol consumption, physical inactivity, and unhealthy diet, while non-modifiable risk factors include age, sex, and family history. It is important to note that having a risk factor does not guarantee that a person will develop the disease, but rather indicates an increased susceptibility.

A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.

Prevalence, in medical terms, refers to the total number of people in a given population who have a particular disease or condition at a specific point in time, or over a specified period. It is typically expressed as a percentage or a ratio of the number of cases to the size of the population. Prevalence differs from incidence, which measures the number of new cases that develop during a certain period.

Combat disorders are a category of mental health conditions that can occur in military personnel as a result of their experiences during combat. These disorders can include post-traumatic stress disorder (PTSD), acute stress disorder, and adjustment disorders, among others. Combat disorders may be caused by exposure to traumatic events, such as experiencing or witnessing combat, the threat of death or serious injury, or the loss of fellow soldiers. Symptoms can include flashbacks, nightmares, avoidance of reminders of the trauma, difficulty sleeping, irritability, and feelings of detachment or numbness. Treatment for combat disorders typically involves a combination of medication and therapy.

I must clarify that I cannot provide a "medical definition" of intelligence, as intelligence is not a concept that is typically defined within the field of medicine. Intelligence is a term used to describe the ability to learn, understand, and make judgments or decisions based on reason, experience, and information. It is often measured through various cognitive abilities such as problem-solving, critical thinking, creativity, and knowledge acquisition.

The concept of intelligence is studied in many fields, including psychology, neuroscience, and education. In medicine, healthcare professionals may assess a person's cognitive abilities to better understand their health status or develop treatment plans. However, there is no specific "medical definition" for intelligence. Instead, it is a multifaceted concept that can be influenced by various genetic, environmental, and experiential factors.

Social behavior, in the context of medicine and psychology, refers to the ways in which individuals interact and engage with others within their social environment. It involves various actions, communications, and responses that are influenced by cultural norms, personal values, emotional states, and cognitive processes. These behaviors can include but are not limited to communication, cooperation, competition, empathy, altruism, aggression, and conformity.

Abnormalities in social behavior may indicate underlying mental health conditions such as autism spectrum disorder, schizophrenia, or personality disorders. Therefore, understanding and analyzing social behavior is an essential aspect of diagnosing and treating various psychological and psychiatric conditions.

"Long-Evans" is a strain of laboratory rats commonly used in scientific research. They are named after their developers, the scientists Long and Evans. This strain is albino, with a brownish-black hood over their eyes and ears, and they have an agouti (salt-and-pepper) color on their backs. They are often used as a model organism due to their size, ease of handling, and genetic similarity to humans. However, I couldn't find any specific medical definition related to "Long-Evans rats" as they are not a medical condition or disease.

Paresis is a medical term that refers to a partial loss of voluntary muscle function. It is often described as muscle weakness, and it can affect one or several parts of the body. Paresis can be caused by various conditions, including nerve damage, stroke, spinal cord injuries, multiple sclerosis, and infections like polio or botulism. The severity of paresis can range from mild to severe, depending on the underlying cause and the specific muscles involved. Treatment for paresis typically focuses on addressing the underlying condition causing it.

Neural pathways, also known as nerve tracts or fasciculi, refer to the highly organized and specialized routes through which nerve impulses travel within the nervous system. These pathways are formed by groups of neurons (nerve cells) that are connected in a series, creating a continuous communication network for electrical signals to transmit information between different regions of the brain, spinal cord, and peripheral nerves.

Neural pathways can be classified into two main types: sensory (afferent) and motor (efferent). Sensory neural pathways carry sensory information from various receptors in the body (such as those for touch, temperature, pain, and vision) to the brain for processing. Motor neural pathways, on the other hand, transmit signals from the brain to the muscles and glands, controlling movements and other effector functions.

The formation of these neural pathways is crucial for normal nervous system function, as it enables efficient communication between different parts of the body and allows for complex behaviors, cognitive processes, and adaptive responses to internal and external stimuli.

Anxiety: A feeling of worry, nervousness, or unease, typically about an imminent event or something with an uncertain outcome. In a medical context, anxiety refers to a mental health disorder characterized by feelings of excessive and persistent worry, fear, or panic that interfere with daily activities. It can also be a symptom of other medical conditions, such as heart disease, diabetes, or substance abuse disorders. Anxiety disorders include generalized anxiety disorder, panic disorder, social anxiety disorder, and phobias.

Antisocial Personality Disorder (ASPD) is a mental health condition characterized by a pervasive pattern of disregard for the rights of others, lack of empathy, and manipulative behaviors. It is defined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), as follows:

A. A consistent pattern of behavior that violates the basic rights of others and major age-appropriate societal norms and rules, as indicated by the presence of at least three of the following:

1. Failure to conform to social norms and laws, indicated by repeatedly performing acts that are grounds for arrest.
2. Deceitfulness, as indicated by repeated lying, use of aliases, or conning others for personal profit or pleasure.
3. Impulsivity or failure to plan ahead; indication of this symptom may include promiscuity.
4. Irritability and aggressiveness, as indicated by repeated physical fights or assaults.
5. Reckless disregard for safety of self or others.
6. Consistent irresponsibility, as indicated by repeated failure to sustain consistent work behavior or honor financial obligations.
7. Lack of remorse, as indicated by being indifferent to or rationalizing having hurt, mistreated, or stolen from another.

B. The individual is at least 18 years of age.

C. There is evidence of conduct disorder with onset before the age of 15 years.

D. The occurrence of antisocial behavior is not exclusively during the course of schizophrenia or bipolar disorder.

E. The individual's criminal behavior has not been better explained by a conduct disorder diagnosis or antisocial behavior that began before the age of 15 years.

It's important to note that ASPD can be challenging to diagnose, and it often requires a comprehensive evaluation from a mental health professional with experience in personality disorders.

'Behavior' is a term used in the medical and scientific community to describe the actions or reactions of an individual in response to internal or external stimuli. It can be observed and measured, and it involves all the responses of a person, including motor responses, emotional responses, and cognitive responses. Behaviors can be voluntary or involuntary, adaptive or maladaptive, and normal or abnormal. They can also be influenced by genetic, physiological, environmental, and social factors. In a medical context, the study of behavior is often relevant to understanding and treating various mental health conditions, such as anxiety disorders, mood disorders, and personality disorders.

Tourette Syndrome (TS) is a neurological disorder characterized by the presence of multiple motor tics and at least one vocal (phonic) tic. These tics are sudden, repetitive, rapid, involuntary movements or sounds that occur for more than a year and are not due to substance use or other medical conditions. The symptoms typically start before the age of 18, with the average onset around 6-7 years old.

The severity, frequency, and types of tics can vary greatly among individuals with TS and may change over time. Common motor tics include eye blinking, facial grimacing, shoulder shrugging, and head or limb jerking. Vocal tics can range from simple sounds like throat clearing, coughing, or barking to more complex phrases or words.

In some cases, TS may be accompanied by co-occurring conditions such as attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety, and depression. These associated symptoms can sometimes have a greater impact on daily functioning than the tics themselves.

The exact cause of Tourette Syndrome remains unclear, but it is believed to involve genetic factors and abnormalities in certain brain regions involved in movement control and inhibition. There is currently no cure for TS, but various treatments, including behavioral therapy and medications, can help manage the symptoms and improve quality of life.

Longitudinal studies are a type of research design where data is collected from the same subjects repeatedly over a period of time, often years or even decades. These studies are used to establish patterns of changes and events over time, and can help researchers identify causal relationships between variables. They are particularly useful in fields such as epidemiology, psychology, and sociology, where the focus is on understanding developmental trends and the long-term effects of various factors on health and behavior.

In medical research, longitudinal studies can be used to track the progression of diseases over time, identify risk factors for certain conditions, and evaluate the effectiveness of treatments or interventions. For example, a longitudinal study might follow a group of individuals over several decades to assess their exposure to certain environmental factors and their subsequent development of chronic diseases such as cancer or heart disease. By comparing data collected at multiple time points, researchers can identify trends and correlations that may not be apparent in shorter-term studies.

Longitudinal studies have several advantages over other research designs, including their ability to establish temporal relationships between variables, track changes over time, and reduce the impact of confounding factors. However, they also have some limitations, such as the potential for attrition (loss of participants over time), which can introduce bias and affect the validity of the results. Additionally, longitudinal studies can be expensive and time-consuming to conduct, requiring significant resources and a long-term commitment from both researchers and study participants.

Clinical competence is the ability of a healthcare professional to provide safe and effective patient care, demonstrating the knowledge, skills, and attitudes required for the job. It involves the integration of theoretical knowledge with practical skills, judgment, and decision-making abilities in real-world clinical situations. Clinical competence is typically evaluated through various methods such as direct observation, case studies, simulations, and feedback from peers and supervisors.

A clinically competent healthcare professional should be able to:

1. Demonstrate a solid understanding of the relevant medical knowledge and its application in clinical practice.
2. Perform essential clinical skills proficiently and safely.
3. Communicate effectively with patients, families, and other healthcare professionals.
4. Make informed decisions based on critical thinking and problem-solving abilities.
5. Exhibit professionalism, ethical behavior, and cultural sensitivity in patient care.
6. Continuously evaluate and improve their performance through self-reflection and ongoing learning.

Maintaining clinical competence is essential for healthcare professionals to ensure the best possible outcomes for their patients and stay current with advances in medical science and technology.

Cognitive Therapy (CT) is a type of psychotherapeutic treatment that helps patients understand the thoughts and feelings that influence behaviors. It is a form of talk therapy where the therapist and the patient work together to identify and change negative or distorted thinking patterns and beliefs, with the goal of improving emotional response and behavior.

Cognitive Therapy is based on the idea that our thoughts, feelings, and behaviors are all interconnected, and that negative or inaccurate thoughts can contribute to problems like anxiety and depression. By identifying and challenging these thoughts, patients can learn to think more realistically and positively, which can lead to improvements in their mood and behavior.

In cognitive therapy sessions, the therapist will help the patient identify negative thought patterns and replace them with healthier, more accurate ways of thinking. The therapist may also assign homework or exercises for the patient to practice between sessions, such as keeping a thought record or challenging negative thoughts.

Cognitive Therapy has been shown to be effective in treating a wide range of mental health conditions, including depression, anxiety disorders, eating disorders, and post-traumatic stress disorder (PTSD). It is often used in combination with other forms of treatment, such as medication, and can be delivered individually or in group settings.

Developmental bone diseases are a group of medical conditions that affect the growth and development of bones. These diseases are present at birth or develop during childhood and adolescence, when bones are growing rapidly. They can result from genetic mutations, hormonal imbalances, or environmental factors such as poor nutrition.

Some examples of developmental bone diseases include:

1. Osteogenesis imperfecta (OI): Also known as brittle bone disease, OI is a genetic disorder that affects the body's production of collagen, a protein necessary for healthy bones. People with OI have fragile bones that break easily and may also experience other symptoms such as blue sclerae (whites of the eyes), hearing loss, and joint laxity.
2. Achondroplasia: This is the most common form of dwarfism, caused by a genetic mutation that affects bone growth. People with achondroplasia have short limbs and a large head relative to their body size.
3. Rickets: A condition caused by vitamin D deficiency or an inability to absorb or use vitamin D properly. This leads to weak, soft bones that can bow or bend easily, particularly in children.
4. Fibrous dysplasia: A rare bone disorder where normal bone is replaced with fibrous tissue, leading to weakened bones and deformities.
5. Scoliosis: An abnormal curvature of the spine that can develop during childhood or adolescence. While not strictly a developmental bone disease, scoliosis can be caused by various underlying conditions such as cerebral palsy, muscular dystrophy, or spina bifida.

Treatment for developmental bone diseases varies depending on the specific condition and its severity. Treatment may include medication, physical therapy, bracing, or surgery to correct deformities and improve function. Regular follow-up with a healthcare provider is essential to monitor growth, manage symptoms, and prevent complications.

Behavior therapy is a type of psychotherapy that focuses on modifying harmful or unhealthy behaviors, thoughts, and emotions by applying learning principles derived from behavioral psychology. The goal of behavior therapy is to reinforce positive behaviors and eliminate negative ones through various techniques such as systematic desensitization, aversion therapy, exposure therapy, and operant conditioning.

Systematic desensitization involves gradually exposing the individual to a feared situation or stimulus while teaching them relaxation techniques to reduce anxiety. Aversion therapy aims to associate an undesirable behavior with an unpleasant stimulus to discourage the behavior. Exposure therapy exposes the individual to a feared situation or object in a controlled and safe environment to help them overcome their fear. Operant conditioning uses reinforcement and punishment to encourage desirable behaviors and discourage undesirable ones.

Behavior therapy has been found to be effective in treating various mental health conditions, including anxiety disorders, phobias, depression, obsessive-compulsive disorder, post-traumatic stress disorder, and substance use disorders. It is often used in combination with other forms of therapy and medication to provide a comprehensive treatment plan for individuals seeking help for mental health concerns.

A psychological interview is a clinical assessment tool used by mental health professionals to gather information about a person's cognitive, emotional, and behavioral status. It is a structured or unstructured conversation between the clinician and the client aimed at understanding the client's symptoms, concerns, personal history, current life situation, and any other relevant factors that contribute to their psychological state.

The interview may cover various topics such as the individual's mental health history, family background, social relationships, education, occupation, coping mechanisms, and substance use. The clinician will also assess the person's cognitive abilities, emotional expression, thought processes, and behavior during the interview to help form a diagnosis or treatment plan.

The psychological interview is an essential component of a comprehensive mental health evaluation, as it provides valuable insights into the individual's subjective experiences and helps establish a therapeutic relationship between the clinician and the client. It can be conducted in various settings, including hospitals, clinics, private practices, or community centers.

Locomotion, in a medical context, refers to the ability to move independently and change location. It involves the coordinated movement of the muscles, bones, and nervous system that enables an individual to move from one place to another. This can include walking, running, jumping, or using assistive devices such as wheelchairs or crutches. Locomotion is a fundamental aspect of human mobility and is often assessed in medical evaluations to determine overall health and functioning.

Physiological adaptation refers to the changes or modifications that occur in an organism's biological functions or structures as a result of environmental pressures or changes. These adaptations enable the organism to survive and reproduce more successfully in its environment. They can be short-term, such as the constriction of blood vessels in response to cold temperatures, or long-term, such as the evolution of longer limbs in animals that live in open environments.

In the context of human physiology, examples of physiological adaptation include:

1. Acclimatization: The process by which the body adjusts to changes in environmental conditions, such as altitude or temperature. For example, when a person moves to a high-altitude location, their body may produce more red blood cells to compensate for the lower oxygen levels, leading to improved oxygen delivery to tissues.

2. Exercise adaptation: Regular physical activity can lead to various physiological adaptations, such as increased muscle strength and endurance, enhanced cardiovascular function, and improved insulin sensitivity.

3. Hormonal adaptation: The body can adjust hormone levels in response to changes in the environment or internal conditions. For instance, during prolonged fasting, the body releases stress hormones like cortisol and adrenaline to help maintain energy levels and prevent muscle wasting.

4. Sensory adaptation: Our senses can adapt to different stimuli over time. For example, when we enter a dark room after being in bright sunlight, it takes some time for our eyes to adjust to the new light level. This process is known as dark adaptation.

5. Aging-related adaptations: As we age, various physiological changes occur that help us adapt to the changing environment and maintain homeostasis. These include changes in body composition, immune function, and cognitive abilities.

Genetic predisposition to disease refers to an increased susceptibility or vulnerability to develop a particular illness or condition due to inheriting specific genetic variations or mutations from one's parents. These genetic factors can make it more likely for an individual to develop a certain disease, but it does not guarantee that the person will definitely get the disease. Environmental factors, lifestyle choices, and interactions between genes also play crucial roles in determining if a genetically predisposed person will actually develop the disease. It is essential to understand that having a genetic predisposition only implies a higher risk, not an inevitable outcome.

Parkinson's disease is a progressive neurodegenerative disorder that affects movement. It is characterized by the death of dopamine-producing cells in the brain, specifically in an area called the substantia nigra. The loss of these cells leads to a decrease in dopamine levels, which results in the motor symptoms associated with Parkinson's disease. These symptoms can include tremors at rest, stiffness or rigidity of the limbs and trunk, bradykinesia (slowness of movement), and postural instability (impaired balance and coordination). In addition to these motor symptoms, non-motor symptoms such as cognitive impairment, depression, anxiety, and sleep disturbances are also common in people with Parkinson's disease. The exact cause of Parkinson's disease is unknown, but it is thought to be a combination of genetic and environmental factors. There is currently no cure for Parkinson's disease, but medications and therapies can help manage the symptoms and improve quality of life.

Recessive genes refer to the alleles (versions of a gene) that will only be expressed when an individual has two copies of that particular allele, one inherited from each parent. If an individual inherits one recessive allele and one dominant allele for a particular gene, the dominant allele will be expressed and the recessive allele will have no effect on the individual's phenotype (observable traits).

Recessive genes can still play a role in determining an individual's genetic makeup and can be passed down through generations even if they are not expressed. If two carriers of a recessive gene have children, there is a 25% chance that their offspring will inherit two copies of the recessive allele and exhibit the associated recessive trait.

Examples of genetic disorders caused by recessive genes include cystic fibrosis, sickle cell anemia, and albinism.

Binge-Eating Disorder (BED) is a type of eating disorder characterized by recurrent episodes of consuming large amounts of food in a short period of time, often to the point of discomfort or pain. These episodes are accompanied by a loss of control over eating and are not followed by compensatory behaviors such as purging or excessive exercise.

To be diagnosed with BED, an individual must experience these binge-eating episodes at least once a week for three months or more, along with feelings of distress, shame, or guilt about their eating habits. Additionally, the binge eating must occur on average at least once a week for three months.

BED is different from overeating and can cause significant emotional and physical problems, including depression, anxiety, obesity, and other health issues related to weight gain. It is important to seek professional help if you suspect that you or someone you know may have BED.

The cerebellum is a part of the brain that lies behind the brainstem and is involved in the regulation of motor movements, balance, and coordination. It contains two hemispheres and a central portion called the vermis. The cerebellum receives input from sensory systems and other areas of the brain and spinal cord and sends output to motor areas of the brain. Damage to the cerebellum can result in problems with movement, balance, and coordination.

Postural balance is the ability to maintain, achieve, or restore a state of equilibrium during any posture or activity. It involves the integration of sensory information (visual, vestibular, and proprioceptive) to control and adjust body position in space, thereby maintaining the center of gravity within the base of support. This is crucial for performing daily activities and preventing falls, especially in older adults and individuals with neurological or orthopedic conditions.

Molecular sequence data refers to the specific arrangement of molecules, most commonly nucleotides in DNA or RNA, or amino acids in proteins, that make up a biological macromolecule. This data is generated through laboratory techniques such as sequencing, and provides information about the exact order of the constituent molecules. This data is crucial in various fields of biology, including genetics, evolution, and molecular biology, allowing for comparisons between different organisms, identification of genetic variations, and studies of gene function and regulation.

Musculoskeletal abnormalities refer to structural and functional disorders that affect the musculoskeletal system, which includes the bones, muscles, cartilages, tendons, ligaments, joints, and other related tissues. These abnormalities can result from genetic factors, trauma, overuse, degenerative processes, infections, or tumors. They may cause pain, stiffness, limited mobility, deformity, weakness, and susceptibility to injuries. Examples of musculoskeletal abnormalities include osteoarthritis, rheumatoid arthritis, scoliosis, kyphosis, lordosis, fractures, dislocations, tendinitis, bursitis, myopathies, and various congenital conditions.

In medical terms, the arm refers to the upper limb of the human body, extending from the shoulder to the wrist. It is composed of three major bones: the humerus in the upper arm, and the radius and ulna in the lower arm. The arm contains several joints, including the shoulder joint, elbow joint, and wrist joint, which allow for a wide range of motion. The arm also contains muscles, blood vessels, nerves, and other soft tissues that are essential for normal function.

Reproducibility of results in a medical context refers to the ability to obtain consistent and comparable findings when a particular experiment or study is repeated, either by the same researcher or by different researchers, following the same experimental protocol. It is an essential principle in scientific research that helps to ensure the validity and reliability of research findings.

In medical research, reproducibility of results is crucial for establishing the effectiveness and safety of new treatments, interventions, or diagnostic tools. It involves conducting well-designed studies with adequate sample sizes, appropriate statistical analyses, and transparent reporting of methods and findings to allow other researchers to replicate the study and confirm or refute the results.

The lack of reproducibility in medical research has become a significant concern in recent years, as several high-profile studies have failed to produce consistent findings when replicated by other researchers. This has led to increased scrutiny of research practices and a call for greater transparency, rigor, and standardization in the conduct and reporting of medical research.

Dissociative disorders are a group of mental health conditions characterized by disruptions or dysfunctions in memory, consciousness, identity, or perception. These disturbances can be sudden or ongoing and can interfere significantly with a person's ability to function in daily life. The main types of dissociative disorders include:

1. Dissociative Amnesia: This disorder is characterized by an inability to recall important personal information, usually due to trauma or stress.
2. Dissociative Identity Disorder (formerly known as Multiple Personality Disorder): In this disorder, a person exhibits two or more distinct identities or personalities that recurrently take control of their behavior.
3. Depersonalization/Derealization Disorder: This disorder involves persistent or recurring feelings of detachment from one's self (depersonalization) or the environment (derealization).
4. Other Specified Dissociative Disorder and Unspecified Dissociative Disorder: These categories are used for disorders that do not meet the criteria for any of the specific dissociative disorders but still cause significant distress or impairment.

Dissociative disorders often develop as a way to cope with trauma, stress, or other overwhelming life experiences. Treatment typically involves psychotherapy, including cognitive-behavioral therapy (CBT) and dialectical behavior therapy (DBT), as well as medication for co-occurring conditions such as anxiety or depression.

Dysthymic disorder, also known as persistent depressive disorder, is a chronic type of depression where a person's moods are regularly low. It is characterized by depressed mood that occurs for most of the day, for at least two years, and is accompanied by at least two other symptoms such as appetite or sleep changes, low energy, low self-esteem, difficulty making decisions, or feelings of hopelessness.

To meet the diagnostic criteria, the symptoms cannot be explained by substance abuse or a medical condition, and they must cause significant distress or impairment in social, occupational, or other important areas of functioning. Dysthymic disorder typically has a chronic course, but it may respond to treatment, including psychotherapy and medication.

Genetic testing is a type of medical test that identifies changes in chromosomes, genes, or proteins. The results of a genetic test can confirm or rule out a suspected genetic condition or help determine a person's chance of developing or passing on a genetic disorder. Genetic tests are performed on a sample of blood, hair, skin, amniotic fluid (the fluid that surrounds a fetus during pregnancy), or other tissue. For example, a physician may recommend genetic testing to help diagnose a genetic condition, confirm the presence of a gene mutation known to increase the risk of developing certain cancers, or determine the chance for a couple to have a child with a genetic disorder.

There are several types of genetic tests, including:

* Diagnostic testing: This type of test is used to identify or confirm a suspected genetic condition in an individual. It may be performed before birth (prenatal testing) or at any time during a person's life.
* Predictive testing: This type of test is used to determine the likelihood that a person will develop a genetic disorder. It is typically offered to individuals who have a family history of a genetic condition but do not show any symptoms themselves.
* Carrier testing: This type of test is used to determine whether a person carries a gene mutation for a genetic disorder. It is often offered to couples who are planning to have children and have a family history of a genetic condition or belong to a population that has an increased risk of certain genetic disorders.
* Preimplantation genetic testing: This type of test is used in conjunction with in vitro fertilization (IVF) to identify genetic changes in embryos before they are implanted in the uterus. It can help couples who have a family history of a genetic disorder or who are at risk of having a child with a genetic condition to conceive a child who is free of the genetic change in question.
* Pharmacogenetic testing: This type of test is used to determine how an individual's genes may affect their response to certain medications. It can help healthcare providers choose the most effective medication and dosage for a patient, reducing the risk of adverse drug reactions.

It is important to note that genetic testing should be performed under the guidance of a qualified healthcare professional who can interpret the results and provide appropriate counseling and support.

Sleep is a complex physiological process characterized by altered consciousness, relatively inhibited sensory activity, reduced voluntary muscle activity, and decreased interaction with the environment. It's typically associated with specific stages that can be identified through electroencephalography (EEG) patterns. These stages include rapid eye movement (REM) sleep, associated with dreaming, and non-rapid eye movement (NREM) sleep, which is further divided into three stages.

Sleep serves a variety of functions, including restoration and strengthening of the immune system, support for growth and development in children and adolescents, consolidation of memory, learning, and emotional regulation. The lack of sufficient sleep or poor quality sleep can lead to significant health problems, such as obesity, diabetes, cardiovascular disease, and even cognitive decline.

The American Academy of Sleep Medicine (AASM) defines sleep as "a period of daily recurring natural rest during which consciousness is suspended and metabolic processes are reduced." However, it's important to note that the exact mechanisms and purposes of sleep are still being researched and debated among scientists.

I'm sorry for any confusion, but "music" is not a term that has a medical definition. Music is a form of art that uses sound organized in time. It may include elements such as melody, harmony, rhythm, and dynamics. While music can have various psychological and physiological effects on individuals, it is not considered a medical term with a specific diagnosis or treatment application. If you have any questions related to medicine or health, I'd be happy to try to help answer those for you!

A cross-sectional study is a type of observational research design that examines the relationship between variables at one point in time. It provides a snapshot or a "cross-section" of the population at a particular moment, allowing researchers to estimate the prevalence of a disease or condition and identify potential risk factors or associations.

In a cross-sectional study, data is collected from a sample of participants at a single time point, and the variables of interest are measured simultaneously. This design can be used to investigate the association between exposure and outcome, but it cannot establish causality because it does not follow changes over time.

Cross-sectional studies can be conducted using various data collection methods, such as surveys, interviews, or medical examinations. They are often used in epidemiology to estimate the prevalence of a disease or condition in a population and to identify potential risk factors that may contribute to its development. However, because cross-sectional studies only provide a snapshot of the population at one point in time, they cannot account for changes over time or determine whether exposure preceded the outcome.

Therefore, while cross-sectional studies can be useful for generating hypotheses and identifying potential associations between variables, further research using other study designs, such as cohort or case-control studies, is necessary to establish causality and confirm any findings.

Follow-up studies are a type of longitudinal research that involve repeated observations or measurements of the same variables over a period of time, in order to understand their long-term effects or outcomes. In medical context, follow-up studies are often used to evaluate the safety and efficacy of medical treatments, interventions, or procedures.

In a typical follow-up study, a group of individuals (called a cohort) who have received a particular treatment or intervention are identified and then followed over time through periodic assessments or data collection. The data collected may include information on clinical outcomes, adverse events, changes in symptoms or functional status, and other relevant measures.

The results of follow-up studies can provide important insights into the long-term benefits and risks of medical interventions, as well as help to identify factors that may influence treatment effectiveness or patient outcomes. However, it is important to note that follow-up studies can be subject to various biases and limitations, such as loss to follow-up, recall bias, and changes in clinical practice over time, which must be carefully considered when interpreting the results.

Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.

Psychological stress is the response of an individual's mind and body to challenging or demanding situations. It can be defined as a state of emotional and physical tension resulting from adversity, demand, or change. This response can involve a variety of symptoms, including emotional, cognitive, behavioral, and physiological components.

Emotional responses may include feelings of anxiety, fear, anger, sadness, or frustration. Cognitive responses might involve difficulty concentrating, racing thoughts, or negative thinking patterns. Behaviorally, psychological stress can lead to changes in appetite, sleep patterns, social interactions, and substance use. Physiologically, the body's "fight-or-flight" response is activated, leading to increased heart rate, blood pressure, muscle tension, and other symptoms.

Psychological stress can be caused by a wide range of factors, including work or school demands, financial problems, relationship issues, traumatic events, chronic illness, and major life changes. It's important to note that what causes stress in one person may not cause stress in another, as individual perceptions and coping mechanisms play a significant role.

Chronic psychological stress can have negative effects on both mental and physical health, increasing the risk of conditions such as anxiety disorders, depression, heart disease, diabetes, and autoimmune diseases. Therefore, it's essential to identify sources of stress and develop effective coping strategies to manage and reduce its impact.

Psychological adaptation refers to the process by which individuals adjust and cope with stressors, challenges, or changes in their environment or circumstances. It involves modifying thoughts, feelings, behaviors, and copabilities to reduce the negative impact of these stressors and promote well-being. Psychological adaptation can occur at different levels, including intrapersonal (within the individual), interpersonal (between individuals), and cultural (within a group or society).

Examples of psychological adaptation include:

* Cognitive restructuring: changing negative thoughts and beliefs to more positive or adaptive ones
* Emotion regulation: managing and reducing intense or distressing emotions
* Problem-solving: finding solutions to practical challenges or obstacles
* Seeking social support: reaching out to others for help, advice, or comfort
* Developing coping strategies: using effective ways to deal with stressors or difficulties
* Cultivating resilience: bouncing back from adversity and learning from negative experiences.

Psychological adaptation is an important aspect of mental health and well-being, as it helps individuals adapt to new situations, overcome challenges, and maintain a sense of control and optimism in the face of stressors or changes.

Sprague-Dawley rats are a strain of albino laboratory rats that are widely used in scientific research. They were first developed by researchers H.H. Sprague and R.C. Dawley in the early 20th century, and have since become one of the most commonly used rat strains in biomedical research due to their relatively large size, ease of handling, and consistent genetic background.

Sprague-Dawley rats are outbred, which means that they are genetically diverse and do not suffer from the same limitations as inbred strains, which can have reduced fertility and increased susceptibility to certain diseases. They are also characterized by their docile nature and low levels of aggression, making them easier to handle and study than some other rat strains.

These rats are used in a wide variety of research areas, including toxicology, pharmacology, nutrition, cancer, and behavioral studies. Because they are genetically diverse, Sprague-Dawley rats can be used to model a range of human diseases and conditions, making them an important tool in the development of new drugs and therapies.

In a medical context, feedback refers to the information or data about the results of a process, procedure, or treatment that is used to evaluate and improve its effectiveness. This can include both quantitative data (such as vital signs or laboratory test results) and qualitative data (such as patient-reported symptoms or satisfaction). Feedback can come from various sources, including patients, healthcare providers, medical equipment, and electronic health records. It is an essential component of quality improvement efforts, allowing healthcare professionals to make informed decisions about changes to care processes and treatments to improve patient outcomes.

The cerebral cortex is the outermost layer of the brain, characterized by its intricate folded structure and wrinkled appearance. It is a region of great importance as it plays a key role in higher cognitive functions such as perception, consciousness, thought, memory, language, and attention. The cerebral cortex is divided into two hemispheres, each containing four lobes: the frontal, parietal, temporal, and occipital lobes. These areas are responsible for different functions, with some regions specializing in sensory processing while others are involved in motor control or associative functions. The cerebral cortex is composed of gray matter, which contains neuronal cell bodies, and is covered by a layer of white matter that consists mainly of myelinated nerve fibers.

Perceptual and Motor Skills. 104 (3 Pt 2): 1355-66. doi:10.2466/pms.104.4.1355-1366. PMID 17879670. S2CID 11775613. Caulfield ... "Behavioral correlates of developmental expressive language disorder". J Abnorm Child Psychol. 17 (2): 187-201. doi:10.1007/ ... January 2012). "Genetic variants of FOXP2 and KIAA0319/TTRAP/THEM2 locus are associated with altered brain activation in ... Expressive language disorder is one of the "specific developmental disorders of speech and language" recognised by the tenth ...
Neurodevelopmental disorders, Rare genetic syndromes, Neurogenetic disorders, Syndromes affecting stature, Disorders of ... disrupted fine and gross motor skills. Intellectual disability and learning disability are often present, sometimes ... clinical psychology and psychiatry would be consulted for management and treatment of behavioral and psychiatric disorders. ... Neurodevelopmental anomalies, motor and movement disorders such as hypotonia (most common), dystonia, spasticity, tic disorder ...
She researches the genetic epidemiology of substance abuse and related behavioral disorders. Dick completed her PhD at Indiana ... and abstract problem-solving skills. Dick eventually left WUSTL to join the faculty at Virginia Commonwealth University. As a ... the CHRM2 gene could be correlated with slight differences in performance IQ scores and could affect someone's visual-motor ... Dick, Danielle M.; Nasim, Aashir; Edwards, Alice C. (2014). "Spit for Science: launching a longitudinal study of genetic and ...
About a quarter of cases are caused by a genetic disorder, and about 5% of cases are inherited. Cases of unknown cause affect ... Core components of behavioral treatments include language and social skills acquisition. Typically, one-to-one training is ... Some of the early signs can include: Delays in reaching, or failure to achieve milestones in motor skills development (sitting ... About a quarter of cases are caused by a genetic disorder. Cases of unknown cause affect about 95 million people as of 2013[ ...
"A prospective genetic marker of the visual perception disorder Meares-Irlen syndrome". Perceptual and Motor Skills. 114 (3): ... Behavioral Optometry, and Ophthalmological and Behavioral Optics, among others. The condition has been studied in several ... Perceptual and Motor Skills. 89 (1): 83-113. doi:10.2466/pms.1999.89.1.83. PMID 10544403. S2CID 26076221. Wilkins, A.J.; Evans ... Perceptual and Motor Skills. 91 (3 Pt 1): 707-724. doi:10.2466/pms.2000.91.3.707. PMID 11153837. S2CID 45587679. Soares, FA; ...
"Behavioral and genetic evidence for a novel animal model of Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive ... Meyer A, Sagvolden T (October 2006). "Fine motor skills in South African children with symptoms of ADHD: influence of subtype, ... Crusio WE (October 2020). "Behavioral and Brain Functions at 15". Behavioral and Brain Functions. 16 (1): 8. doi:10.1186/s12993 ... Sagvolden, T. (1979). Behavioral Changes in Rats with Septal Lesions: Effects of Water-Deprivation Level and Intensity of ...
... visuoconstructive and fine-motor coordination skills; (d) visuospatial memory tasks; (e) reading better than mathematical ... Neurodevelopmental disorders may also be confirmed by genetic testing. Traditionally, disease related genetic and genomic ... behavioral disorders including conduct disorder etc. caused by other heavy metals, such as lead, chromium, platinum etc., ... Motor disorders including developmental coordination disorder, stereotypic movement disorder, and tic disorders (such as ...
Structural defects are seen in the cerebellum too, which affect the motor and communication skills. Sometimes the left lobe of ... as Dysgraphia Communication disorders and Auditory processing disorder Developmental coordination disorder Genetic disorders, ... Other stress theories suggest that even small stresses can accumulate to result in emotional, behavioral, or social disorders ... These disorders comprise developmental language disorder, learning disorders, motor disorders, and autism spectrum disorders. ...
... is a genetic disorder affecting the midbrain and cerebellum of the central nervous system. It is caused by ... Delays in development of some physical, psychological and behavioral skills; progressive enlargement of the head (macrocephaly ... These children may have excessive vomiting, difficulty swallowing and speaking, poor coordination, and loss of motor control. ... Disorders causing seizures, Leukodystrophies, Rare diseases, Demyelinating diseases of CNS, Neurological disorders in children ...
Delayed development of motor skills such as sitting, standing, and walking are commonly exhibited in early childhood. Patients ... Weaver syndrome is a rare autosomal dominant genetic disorder associated with rapid growth beginning in the prenatal period and ... and behavioral problems.[citation needed] The cause for Weaver syndrome was identified in 2011 as autosomal dominant mutations ... "Proposal form for the evaluation of a genetic test for NHS Service Gene Dossier/Additional Provider" (PDF). UK Genetic Testing ...
Poor motor skills and balance, speech impairment, mild gait or hand ataxia and irregular eye movement are symptoms of the ... These three genetic mutations reportedly cover 96% of families with COACH syndrome. The diagnosis of COACH syndrome is based on ... Behavioral and intellectual delays are symptoms caused by the hypoplasia of the cerebellar vermis and oligophrenia. This ... The report concludes by suggesting that more cases of the disorder need to be reported to refine its definition, and assigns ...
Most young children with 1p36 deletion syndrome have delayed development of speech and motor skills. Speech is severely ... 1p36 deletion syndrome is a congenital genetic disorder characterized by moderate to severe intellectual disability, delayed ... Behavioral problems are also common, and include temper outbursts, banging or throwing objects, striking people, screaming ... The condition is caused by a genetic deletion (loss of a segment of DNA) on the outermost band on the short arm (p) of ...
... motor skills, strength and neuropsychological parameters without any undesirable side effects. Available reports do not reveal ... obsessive-compulsive disorder, and tic severity to social and behavioral problems in tic disorders". J Dev Behav Pediatr. 25 (4 ... "Protection from genetic diathesis in attention-deficit/hyperactivity disorder: possible complementary roles of exercise". ... Combined use of D2-type receptor antagonists and ADHD stimulants for the treatment of ADHD with comorbid behavioral disorders ...
Perceptual and Motor Skills. 115 (3): 811-832. doi:10.2466/03.10.15.PMS.115.6.811-832. PMID 23409595. S2CID 8775922. Saygin D, ... There may be a genetic predisposition in children with separation anxiety disorder. "Separation anxiety disorder in children ... Behavioral inhibition (BI) plays a large role in many anxiety disorders, SAD included. Compared to children without it, ... Specifically disorders including panic disorder and depressive disorders were more likely to occur. Other sources also support ...
Delayed gross motor development Delayed mental development Delayed fine motor skill development Delayed speech and language ... Being a recessive disorder, the disease can only be inherited from both parents since the disorder can only occur when a person ... Saronwala, A.; Tournay, A.; Gargus, J. J. "Genetic inborn error of metabolism provides a unique window into molecular ... development Hypotonia Frequent manifestations include: Seizures Hyporeflexia Ataxia Behavioral problems Hyperkinesis Unusual ...
Damage to the cerebellum causes impairment in motor skills and can cause nystagmus. Almost a third of people with isolated, ... genetic disorders and neurodegenerative diseases (such as progressive supranuclear palsy and multiple system atrophy). Gluten ... Behavioral intervention is successful when it involves engaging knowledge of the interests and general backgrounds of ... "Scale for Ocular motor Disorders in Ataxia (SODA)". Journal of the Neurological Sciences. 443: 120472. doi:10.1016/j.jns. ...
Motor coordination problems affect fine and gross motor movement as well as perceptual-motor skills. Secondary stressors ... typical development (TD) behavioral, emotional and other mental disorders. When compared to MA children there is a bigger ... Genetic factors play a huge roll in neural development. Genetic factors can influence the timing and pattern of neural ... The stages are: Calculatory Automatic Sensory & Motor Circular sensory-motor Sensory-motor Nominal Sentential Preoperational ...
... and factor structure of the Behavioral Dyscontrol Scale". Perceptual and Motor Skills. 74 (3): 883-892. doi:10.2466/pms.1992.74 ... Liability for externalizing spectrum disorders and its genetic and environmental relation to response inhibition across ... Executive functions are impaired in multiple disorders including anxiety disorder, major depressive disorder, bipolar disorder ... Changing one's behavioral response to meet a new goal or modify an objective is a higher level skill that requires a fusion of ...
... but the main focus with antagonists are diseases connected to motor skills, learning and memory, for example Parkinson's and ... The A2A receptor antagonists may be used for treatment of attention deficit hyperactivity disorder (ADHD), because of the ... It was proposed that the cause of behavioral depression was due to inhibition of cyclic nucleotide phosphodiesterases when ... through pharmacological inhibition or genetic deletion. Some effects were found to be due to enhanced activity of natural ...
The administration of testosterone therapy has been shown to improve motor skills, speech, and nonverbal IQ in males with 49, ... It is genetic but not hereditary, meaning that while the genes of the parents cause the syndrome, there is a small chance of ... Impaired speech and maladaptive behavioral problems are typical. One study looked at males that were diagnosed with 48,XXYY, 48 ... As with most categories of aneuploidy disorders, 49,XXXXY syndrome is often accompanied by intellectual disability. It can be ...
Applied behavioral analysis (ABA) is considered the most effective therapy for autism spectrum disorders by the American ... poor motor planning, and toe walking. It was presumed initially that there was a common cause at the genetic, cognitive, and ... ABA focuses on teaching adaptive behaviors like social skills, play skills, or communication skills and diminishing problematic ... Communication disorders, Neurodevelopmental disorders, Pervasive developmental disorders, Wikipedia medicine articles ready to ...
... motor, or language skills similar to those seen in autistic children. Adults with schizophrenia and related psychotic disorders ... Proponents of the hypothesis also point towards genetic disorders with an elevated risk of one disorder and not the other, ... Crespi B, Badcock C (June 2008). "Psychosis and autism as diametrical disorders of the social brain" (PDF). The Behavioral and ... Crespi and Badcock make a number of claims about genetic disorders and their relationship to the hypothesis; for instance, that ...
... or with language and reading skills). Most behavioral genetic research suggests that all autism spectrum disorders have shared ... motor planning disorder), balance, tandem gait, and finger-thumb apposition. There is no evidence that these motor skills ... Autism spectrum disorders, 1976 neologisms, Genetic disorders by system, Neurological disorders, Neurological disorders in ... This coexistence of psychotic disorders is referred to as comorbid disorders. Comorbid disorders can be completely independent ...
... poor fine motor skills, poor gross motor skills, delayed motor skill development (e.g., riding a bicycle at appropriate age) ... "other specified neurodevelopmental disorders" as a way to better study the behavioral aspects of all FASD disorders. Though ... "Genetic and Epigenetic Perspectives on the Role of Fathers in Fetal Alcohol Spectrum Disorder" (PDF). Canada FASD Research ... Attention deficit hyperactive disorder Autism spectrum disorder Reactive attachment disorder Oppositional defiant disorder ...
... a degenerative disorder of the central nervous system that often impairs motor skills and speech. Huntington's disease, a rare ... Most genetic manipulation techniques are also considered permanent. Temporary lesions can be achieved with advanced in genetic ... EEG allows for the investigation of mental disorders, sleep disorders and physiology. It can monitor brain development and ... As a result, a critical assumption in behavioral neuroscience is that organisms share biological and behavioral similarities, ...
... behavioral/emotional functioning, visuospatial abilities, fine motor skills and others. The tests are selected based on the ... ADHD and Learning Disabilities Intellectual Disability Autism Spectrum Disorder Genetic and metabolic syndromes (e.g., ... An Evidence Based Approach to Emotional and Behavioral Disorders. American Psychological Association. ISBN 978-1-4338-1266-8. ... intellectual and developmental disorders (mental retardation), autism spectrum disorders. Some may work in other settings, such ...
Motor impairments are very common in individuals with the disorder. Rates of epilepsy in children with isodicentric ... children of the same age and IQ with autism not caused by a known genetic disorder (i.e., nonsyndromic ASD). The EEG signature ... children with Dup15q syndrome had significantly greater motor impairment and impairment of daily living skills than children in ... "Identification of a distinct developmental and behavioral profile in children with Dup15q syndrome." Journal of ...
Symptoms most frequently associated with this disease are movement disorders, including impaired motor function, behavioral ... Rubinstein-Taybi syndrome (RTS) is a rare genetic disorder that is the result of genetic mutations in either CBP or p300. RTS ... For mice with homozygous point mutations in their CBP KIX domain, they demonstrated impaired motor skill learning and execution ... Symptoms of these disorders include poor cerebellar-dependent learning, motor coordination and impaired balance. In rats with ...
The cause behind motor disorders is not exact, but the cause is usually genetic or environmental. Motor skills disorders are ... Mental disorders diagnosed in childhood can be neurodevelopmental, emotional, or behavioral disorders. These disorders ... "Motor Skills Disorder." e medicine health WebMD. 25 Mar. 2013. Perlstein, David. "Motor Skills Disorder Symptoms." eMedicine ... April 15, 2013, from http://www.emedicinehealth.com/motor_skills_disorder/page3_em.htm#motor_skills_disorder_symptoms American ...
... that has parallels to human speech learning and basal ganglia motor skill learning. The presence of robust adult neurogenesis ... Recent advances in genetic tools and in vivo microscopy allow for the visualization of neuronal migration in the HVC of ... or for the treatment of neurodegenerative disorders. For example, studying the molecular characteristics of the RA projecting ... in this avian circuit and behavioral context allows for the investigation of ways to manipulate adult neurogenesis with ...
Health Conditions Related to Genetic Changes. GRIN2B-related neurodevelopmental disorder. Several dozen mutations in the GRIN2B ... which is characterized by intellectual disability and delayed development of speech and motor skills. Other neurological ... and behavioral problems.. Many GRIN2B gene mutations lead to production of a nonfunctional GluN2B protein or prevent the ... Autism spectrum disorder. MedlinePlus Genetics provides information about Autism spectrum disorder. More About This Health ...
Perceptual and Motor Skills. 104 (3 Pt 2): 1355-66. doi:10.2466/pms.104.4.1355-1366. PMID 17879670. S2CID 11775613. Caulfield ... "Behavioral correlates of developmental expressive language disorder". J Abnorm Child Psychol. 17 (2): 187-201. doi:10.1007/ ... January 2012). "Genetic variants of FOXP2 and KIAA0319/TTRAP/THEM2 locus are associated with altered brain activation in ... Expressive language disorder is one of the "specific developmental disorders of speech and language" recognised by the tenth ...
The disorder is caused by a mutation in the gene known as the survival motor neuron gene (SMN1), which is responsible for the ... and delay in gross and fine motor skills. The abnormal facial features are subtle in infancy and become more noticeable with ... presenting with cognitive and behavioral disabilities, including autism with intellectual disability; attention deficit- ... Counseling Cystic fibrosis Fragile X syndrome Genetic carrier screening Genetic counseling Genetic disorders Genetic testing ...
This leads to the degeneration of motor skills and cognitive abilities, as well as behavioral difficulties. This is a rare ... Neurology & Metabolic disorders. Huntingtons disease. Huntingtons disease is a genetic disorder affecting the central nervous ... Huntingtons disease: a genetic disorder. Huntingtons disease is caused by a gene defect located in the Huntingtin gene ... Chorea and other motor dysfunctions. Typical motor dysfunctions consist of jerky, involuntary movements of the arms (e.g. ...
... and fine and gross motor skills than children with special healthcare needs without heart problems. These children also missed ... About 20% to 30% of people with a CHD have other physical problems or developmental or cognitive disorders.7,8,9 ... At least 15% of CHDs are associated with genetic conditions.5,6 ... and treatment for developmental or behavioral problems. Nearly ...
Pataus syndrome is a serious rare genetic disorder caused by having an additional copy of chromosome 13 in some or all of the ... delayed motor skill development, such as with writing.. *delayed or difficult speech. ... emotional or behavioral issues.. *hand trembling or involuntary muscle movements.. *hypotonia (weak muscle tone) ... A genetic test called a karyotype analysis can confirm a Turner syndrome diagnosis. This test requires a blood draw. It can ...
... behavioral symptoms that are secondary to motor deficits (eg: tantrums in response to loss of motor skills) are not ... or a known genetic disorder other than MLD. 2. History of bone marrow transplant (BMT), hematopoietic stem cell transplantation ... Decline in gross motor function using GMFC MLD:. - Change from baseline at Week 106 and EOS in gross motor function, using the ... To evaluate the effects of IT administration of SHP611 on gross motor function, using the Gross Motor Function Measure 88 (GMFM ...
Learn about SETD1B-Related Neurodevelopmental Disorder, including symptoms, causes, and treatments. If you or a loved one is ... There are very few detailed reports on fine motor skills (such as picking up food or using a pencil) among individuals with ... Genetic Counseling Genetic counselling is recommended, to explain test results and next steps for family members. A genetic ... autism spectrum disorder or autism-like behaviors and other behavioral challenges. Speech disorders, seizures and autism-like ...
... particularly of motor and language skills. Many have mild intellectual disability; behavioral and psychiatric abnormalities ... The disorder is most often diagnosed through genetic analysis with retrospective clinical phenotyping. Symptom onset is usually ... Peroxisome biogenesis disorder 2A (Zellweger). MedGen UID: 763187. •Concept ID: C3550273. •. Disease or Syndrome. ... Peroxisome biogenesis disorder 5A (Zellweger). MedGen UID: 766854. •Concept ID: C3553940. •. Disease or Syndrome. ...
... autism spectrum disorder, and visual and hearing impairments, Delayed development in speech, language, motor skills, and ... genetic disorders, epilepsy, prematurity, diabetes, asthma, cancer). Elizabeth Harstad, MD, MPH We are a specialty private ... and anxiety disorders, Tics, Tourette syndrome, and other habit disorders, Regulatory disorders including sleep disorders, ... Behavioral disorders, including ADHD and oppositional defiant disorder 4. These include: Asking how your child acts in a ...
... a genetic disorder that starves the brain of the dopamine and serotonin required for basic motor and behavioral skills, like ... With genetic sequencing, a sample of a patients DNA is taken through blood, skin, or tissue, for example. Then, their entire ... But genetic testing is also becoming increasingly useful in the presence of rare symptoms. in July, researchers at the ... How Genetic Testing Will Create Personalized Therapeutics for Rare Diseases. September 28, 2021 ...
Some treatments include physical therapy for help in motor skill delays, and behavioral and educational therapy for help with ... genetic disorders, such as Down syndrome and fragile X syndrome. Remember that children develop at different rates, so its ... Fine motor skills include small movements like holding a toy or using a crayon. Gross motor skills require larger movements, ... Fine motor skills are essential to living and learning. Find out what they are and when they develop as well as what to do if ...
... who has a genetic disorder with symptoms similar to cerebral palsy, is living his best possible life thanks to the loving care ... A pediatrician diagnosed Aiden with cerebral palsy (CP), a disorder of movement, muscle tone or motor skills caused by damage ... That led to the discovery that Aiden actually had a GRIN2B mutation, a genetic disorder with symptoms very similar to those of ... Then he was taken to see Adam Aronsky, MD, a developmental and behavioral pediatrician at CSH in Mountainside. Dr. Aronsky felt ...
This is a rare genetic disorder present at birth. It is characterized by intellectual disabilities or learning problems, unique ... Theyre usually characterized by a significant discrepancy between higher verbal skills and weaker motor, visual-spatial, and ... Behavioral and Emotional. Troubled behaviour / troubled teens roubled teens tend to have problems that are intense, persistent ... Fetal Alcohol Spectrum Disorder (FASD) Fetal Alcohol Spectrum Disorder (FASD) is an umbrella term used to describe the range of ...
This is a rare genetic disorder present at birth. It is characterized by intellectual disabilities or learning problems, unique ... Theyre usually characterized by a significant discrepancy between higher verbal skills and weaker motor, visual-spatial, and ... Behavioral and Emotional. Troubled behaviour / troubled teens roubled teens tend to have problems that are intense, persistent ... Fetal Alcohol Spectrum Disorder (FASD) Fetal Alcohol Spectrum Disorder (FASD) is an umbrella term used to describe the range of ...
Using blood samples, we might do genetic tests or look for metabolic disorders. ... Gross motor skills, like walking. *Fine motor skills, including things like holding a spoon ... Behavioral therapy, to help with emotional or mental-health aspects. *Academic coaching, to help with challenges at school ... Social skills, including making eye contact and giving and receiving hugs. After age 5, we watch how well children do in school ...
The diagnosis of dyspraxia or developmental coordination disorder is based on motor coordination skills significantly below the ... A significant improvement in motor and cognitive behavioral assays as well as normalized delta power measured by ... motor and balance deficits, intellectual disabilities, and seizures. The genetic cause of AS is the neuronal loss of UBE3A ... Interventions to help children cope with their activity limitations are effective in improving motor competence and motor skill ...
Each disorder has symptoms commonly seen with autism... ... At least seven disorders are part of or closely related to ... In most cases, there is a regression in cognition, behavior, social, and motor skills throughout their lifetime. ... Angelman syndrome is a genetic disorder that affects the nervous system. Initial symptoms of this disorder typically manifest ... The conditions listed below all exhibit similar behavioral symptoms to autism spectrum disorder. Behavioral treatments for ...
... adults and geriatrics are in need of speech therapy due to a multitude of disorders and injuries. ... play skills, autism spectrum disorder, behavioral management, language delay, cleft palate and lip, speech sound disorders, ... genetic disorders, stroke and brain injury, and progressive neurological disorders. Early detection is key and the following ... motor speech disorders, expressive language, receptive language, reading and writing, alternative and augmentative ...
Parent or pediatric care provider concerns about delays in motor skills, social communication, cognitive skills, adaptive ... Genetic conditions, chromosome abnormalities, neurological disorders or traumatic brain injury. *Monitoring the developmental ... We assess conditions ranging from birth-related complications to motor or language delays, as well as behavioral problems or ... Early signs of autism spectrum disorder or atypical behavior. *Routine developmental follow-up for babies who are at-risk due ...
Dive into an overview of Autism Related Disorders: Gain insights and understanding to navigate this complex landscape. ... Throughout their lives, most people experience a regression in their cognitive, behavioral, social, and motor skills. ... Williams Syndrome (also known as Williams-Beuren syndrome) is a rare genetic disorder characterized by the absence of a portion ... Motor difficulties. Children with motor difficulties may struggle with gross motor skills, such as difficulties in balance, and ...
... and genetic counselors are consulted routinely. Medications to control the behavioral problems associated with this disorder ... Over time, speech and communication skills decline along with other milestones. Cognitive and motor skills diminish. ... and wheelchairs are often required as the disorder progresses to its final and immobile stage. Genetic counseling is also ... In the first stage: The affected child will display delayed speech as well as mild facial abnormalities and behavioral issues. ...
... autism spectrum disorder includes a number of conditions with different symptoms. Learn about what autism is and how its ... Case Reports in Psychiatry: "Targeted Nutritional and Behavioral Feeding Intervention for a Child with Autism Spectrum Disorder ... Developmental: Speech therapy improves communication skills, physical therapy improves motor ability, occupational therapy ... Is autism genetic?. Autism runs in families, so certain combinations of genes may increase a childs risk. Changes in more than ...
Abstract: Pitt-Hopkins Syndrome (PTHS) is a rare genetic disorder caused by insufficient expression of the TCF4 gene found on ... Initial sessions involved behavioral skills training in data collection procedures. Parent training was delivered weekly, ... The individual typically presents with severe expressive language delays (vocal-verbal speech is often absent), motor delays ( ... We discuss considerations when programming for children with autism spectrum disorder with genetic comorbidities and how to ...
Uneven gross/fine motor skills. ADHD Behavioral Checklist:. *Cant talk or play quietly, disrupts others with talk or actions ... ADHD is a genetic disorder as is ASD. Both situations involve children with difficulty learning and difficulty with interacting ... Uneven gross/fine motor skills. Using checklists like these may be the best option in diagnosing a child correctly and not ... In looking at the two disorder checklists, its easy to see that there are similarities and differences.... ASD Behavioral ...
... disorder, also known as Heller syndrome, is characterized by a loss of previously acquired language and social skills and ... and behavioral features of childhood disintegrative disorder resemble those of autistic disorder. Affected children have ... Previously acquired motor skills are lost (eg, a child who was toilet-trained begins to soil during the day and night, or a ... Ortega-Hernandez OD, Kivity S, Shoenfeld Y. Olfaction, psychiatric disorders and autoimmunity: is there a common genetic ...
INTRODUCTION: These changes are the main causes of deficits in perceptual-motor skills responsible for motor skill acquisition ... Children with DS are especially vulnerable to attention impairments because of a genetic neurodevelopmental disorder; ... Hedges et al.15 cited that insights into the behavioral and neurobiological connections relate to the formation of specific ... Downs syndrome is accompanied by multisystem pathologies, which involve delays in basic motor skills, motor impairments, and ...
What are the changes in behavioral characteristic of frontotemporal dementia (FTD)?. What are the signs and symptoms of motor ... The other 73% of cases in their series were not clearly hereditary, and the molecular genetic basis of these disorders is not ... motor skills usually are spared, except for perseverative or inattentive responses and difficulty with temporal sequencing of ... FTD consequently changed from a lobar atrophy of syndromic definition to a group of molecular genetic disorders. Many MAPT ...
... emotional and immune system disorders, genetic damage, hyperactivity, motor skill difficulties, mouth sores, muscle weakness, ... problems-behavioral and emotional, reproductive damage, scalp eruptions, skin irritation, strips skin of protective oils and ... Fungicide, Insecticide & Pesticides: ADD, birth defects, cancer, death, dizziness, fatigue, flu-like symptoms, genetic ... Heavy Metals (Toxic): abdominal cramps, Alzheimers, brain disorder, cancer, ...
... is a complex neurodevelopmental disorder that impacts social, speech, behavioral and motor skills. It is a spectrum disorder ... cause may be both are related to genetic and environmental causes and are both related to some type of brain disorder. Evidence ... behavioral and social outcomes than individuals diagnosed with autism only including issues with motor and daily living skills. ... Posted in Cerebral Palsy, Chidren/Teens, Children with Special Needs , Tagged aspiration, digestive disorders, dysgraphia, ...
  • But genetic testing is also becoming increasingly useful in the presence of rare symptoms. (opensourcebiology.eu)
  • Signs and symptoms of ASD vary, but usually include delayed speech and language skills and challenges communicating and interacting with others. (healthline.com)
  • That led to the discovery that Aiden actually had a GRIN2B mutation, a genetic disorder with symptoms very similar to those of CP. (rwjbh.org)
  • Each disorder has symptoms commonly seen with autism, as well as its own specific symptoms. (autism.org)
  • Medical comorbidities are also commonly seen in autism spectrum disorder including PANS/PANDAS , ADD/ADHD, seizures, dental issues, sleep disturbances and gastrointestinal symptoms. (autism.org)
  • The conditions listed below all exhibit similar behavioral symptoms to autism spectrum disorder. (autism.org)
  • The typical symptoms of this disorder include a body type that is compact, underdeveloped sexual traits, weak muscular tone, and an obsession with food that is frequently accompanied by impulsive eating. (prayatna.co.in)
  • In most cases, treatment is limited to reducing or controlling the symptoms of this disorder by making sure that neurologists, ophthalmologists, and genetic counselors are consulted routinely. (levislifelovelaughter.org)
  • A case report of a patient with symptoms of childhood disintegrative disorder at age 4 years determined that the patient had a sialylation deficiency and an increase of asialo-core fucosylated bisected N-glycans, aberrant N-glycan structures of CSF even though there were no changes of total plasma N-glycan strucutres of CSF proteins. (medscape.com)
  • Additional symptoms of childhood disintegrative disorder may include the onset of difficulty in the transition to waking from sleep. (medscape.com)
  • Typically, the earlier the symptoms appear, the more severe the behavioral problems are. (docvita.com)
  • There are currently no approved medications for treating core autism spectrum disorders (ASD) symptoms, which include persistent deficits in social communication and restricted and repetitive patterns of behavior or interests [ 1 ]. (nature.com)
  • Consistent with the reports, children with autism disorders are unique, explaining that no two autistics generate equivalent symptoms. (madhyapradeshmirror.com)
  • People with juvenile and adult MLD may display motor and/or cognitive symptoms such as challenges remembering, carrying out multiple-step activities and doing schoolwork or job tasks. (allstripes.com)
  • The condition is not treatable, so associated symptoms - significant behavioral changes, motor disorders, and loss of language skills - persist and worsen with time. (mentalhealth.com)
  • Symptoms include inappropriate social behavior, a loss of ability to recognize others' feelings, and reduced language and cognitive skills. (mentalhealth.com)
  • PPA most often involves the inability to name objects and find words, though other symptoms, including motor speech problems and reduced language comprehension, are often present. (mentalhealth.com)
  • Other common behavioral symptoms include impulsivity, social withdrawal, and feelings of restlessness. (mentalhealth.com)
  • Intellectual disability is subdivided into syndromic intellectual disability, in which intellectual deficits associated with other medical and behavioral signs and symptoms are present, and non-syndromic intellectual disability, in which intellectual deficits appear without other abnormalities. (nursing-assignments.com)
  • Children with SPD struggle with how to process stimulation, which can cause a wide range of symptoms including hypersensitivity to sound, sight and touch, poor fine motor skills and easy distractibility. (ucsf.edu)
  • For juvenile Huntington's disease, the symptoms are difficulty paying attention, rapid/significant drop in overall school performance, behavioral problems, contracted/rigid muscles that affect gait, tremors/slight involuntary movements, frequent falls/clumsiness, and seizures. (demystifyingyourhealth.com)
  • When this energy engine of the cell does not work correctly, many organs in the body-especially those that require a high amount of energy (like the brain, gastrointestinal tract, and immune system)-may not function correctly, resulting in symptoms seen in mitochondrial disorders. (autismfile.com)
  • Recently we also pointed out that symptoms of mitochondrial disorders overlap the symptoms commonly seen in ASD [5, 6]. (autismfile.com)
  • Since this disorder has a broad range of symptoms and severity, the term spectrum is added to the name to signal the symptoms and severity. (eminencepapers.com)
  • HD is typically diagnosed based on clinical symptoms, including the presence of chorea, and a family history of HD, and is confirmed by genetic testing. (arupconsult.com)
  • Although a diagnosis of HD is largely based on clinical symptoms, the gold standard for diagnosis is genetic testing. (arupconsult.com)
  • Diagnostic genetic testing is indicated for individuals with or without a family history of HD after the onset of motor symptoms, particularly those severe enough to receive a score of 4 on the Unified Huntington's Disease Rating Scale (UHDRS) . (arupconsult.com)
  • The progressive nature of the disorder, the variation in symptoms, and the complexity of diagnosis and treatment is well portrayed in a case study published by Lipe and Bird. (medscape.com)
  • Now that the genetic mutation has been discovered, doctors can use a simple blood test to diagnose a person who shows symptoms of the disease. (lu.se)
  • Behavioral disorders, including ADHD and oppositional defiant disorder 4. (expressextension.com)
  • ADHD and Oppositional Defiant Disorder (ODD) are two diagnoses that children with autism often get diagnosed with. (myaspergerschild.com)
  • Is this the same as an oppositional defiant disorder? (docvita.com)
  • Behavior characteristics include mouthing or chewing non-food items, decreased perception of pain, and autism spectrum disorder or autistic-like affect and behavior. (nih.gov)
  • The Division of Developmental and Behavioral Pediatrics strives to provide excellent care for children with developmental delays/concerns, autism, ADHD, ADD, Down syndrome, other genetic syndromes associated with developmental delay, learning disabilities, intellectual disabilities, fussy babies, and/or behavior concerns. (expressextension.com)
  • Several treatments are recommended for individuals with this disorder, including mild medications for behavior problems and therapies for speech and language and sensory improvement. (autism.org)
  • Autism , also called autism spectrum disorder (ASD), is a complicated, lifelong condition that includes problems with communication and behavior. (webmd.com)
  • Conduct disorder (CD) is a disorder of childhood and adolescence that comprises a pattern of persistent and repetitive aggressive behavior. (docvita.com)
  • and psychological measures of social behavior, communication skills, and obsessive-compulsive behaviors. (ku.edu)
  • FTD is a cognitive disorder that affects a person's behavior, motor abilities, and language skills. (mentalhealth.com)
  • Behavioral variant - Known as bvFTD, this version involves a loss of control regarding behavior. (mentalhealth.com)
  • Adaptive behavior is defined in terms of conceptual, social, and practical skills involving tasks performed by people in their everyday lives. (nursing-assignments.com)
  • Behavioral problems are common and can include temper tantrums, obsessive/compulsive behavior and skin picking. (rarediseases.org)
  • She also exhibited avoidance behavior toward strangers and learning disorders, with an IQ of 75. (care4ash1l.com)
  • All four individuals (100%) had MCA, three (75%) exhibited abnormal behavior, two (50%) had a sleep disorder, and one (25%) experienced seizure. (care4ash1l.com)
  • Five (50%) individuals had MCA, seven (70%) had abnormal behavior, six (60%) had a sleep disorder, and four (40%) experienced seizures. (care4ash1l.com)
  • Diagnosis is based on careful assessment of behavior, cognitive development , and language skills. (amboss.com)
  • Huntington's manifests itself through motor dysfunction and through emotional changes that can vary extensively. (aop-health.com)
  • emotional or behavioral issues. (winetourismday.org)
  • These in turn may reduce learning capacity and increase risk of academic failure 8 , poor social relationships and long-term behavioral and emotional problems 9 . (bvsalud.org)
  • Our team also identifies and helps you manage emotional, regulatory or habit disorders that affect your child's ability to live a high-quality life. (lvhn.org)
  • Our developmental-behavioral pediatricians have expert training to care for the emotional, developmental and learning needs of children and teens. (lvhn.org)
  • Endocannabinoids, including anandamide (AEA) and 2-arachidonoyl glycerol (2-AG), are lipid neuromodulators that regulate excitatory and inhibitory synaptic transmission through the activation of cannabinoid receptors and impact a variety of behavioral indices, including cognitive function, emotional regulation, social motivation, and reward processing [ 5 ]. (nature.com)
  • 8] Even when poor academic performance is recognized, it may take expert assessment to distinguish mild intellectual disability from specific learning disability or emotional/behavioral disorders. (nursing-assignments.com)
  • and emotional and behavioral changes) and for asymptomatic adults with a family history of HD. (arupconsult.com)
  • Childhood disintegrative (or disintegration) disorder, also known as Heller syndrome, and now subsumed under the Autism Spectrum Disorders (ASDs) category in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition ( DSM5 ), is characterized by a loss of previously acquired language and social skills and results in a persistent delay in these areas. (medscape.com)
  • More people live with epilepsy than autism, spectrum disorders, Parkinson's disease, multiple sclerosis and cerebral palsy combined. (specialneedsresourceblog.com)
  • Autism spectrum disorders (ASDs) - which include autistic disorder, Asperger's Syndrome, and pervasive developmental disorder-not otherwise specified (PDD-NOS) - are defined by behavioral observations and characterized by impairments in communication and social interaction, along with restrictive and repetitive behaviors [1]. (autismfile.com)
  • Human GRIN2B variants in neurodevelopmental disorders. (medlineplus.gov)
  • In a groundbreaking new study from UC San Francisco, researchers have found that children affected with SPD have quantifiable differences in brain structure, for the first time showing a biological basis for the disease that sets it apart from other neurodevelopmental disorders. (ucsf.edu)
  • According to the National Autism Spectrum Disorder Surveillance System (NASS) (2018), Autism Spectrum Disorder (ASD) is diagnosed in 1 in 66 Canadian children and youth (ages 5-17), making it one of the most common neurodevelopmental disorders in children. (care4ash1l.com)
  • Definition of Developmental Disorders Developmental disorders are better called neurodevelopmental disorders. (msdmanuals.com)
  • Neurodevelopmental disorders are neurologically based conditions that can interfere with the acquisition, retention, or. (msdmanuals.com)
  • In general, when a patient is diagnosed with SETD1B -NDD, it is recommended that at minimum, patients be referred to a geneticist or genetic counselor, neurologist and developmental pediatrician. (rarediseases.org)
  • Here are some of the things some developmental-behavioral pediatrician might evaluate for: Delayed development in speech, language or motor skills, Nonverbal learning disabilities or other The diagnosis may not be clear yet, or there might not be a diagnosis that applies. (expressextension.com)
  • is a developmental behavioral pediatrician at Boston Children's Hospital. (expressextension.com)
  • That professional is called a developmental-behavioral pediatrician. (expressextension.com)
  • A pediatrician diagnosed Aiden with cerebral palsy (CP), a disorder of movement, muscle tone or motor skills caused by damage to or abnormal development of the brain. (rwjbh.org)
  • Then he was taken to see Adam Aronsky, MD , a developmental and behavioral pediatrician at CSH in Mountainside. (rwjbh.org)
  • Lehigh Valley Reilly Children's Hospital offers a developmental-behavioral pediatrician who diagnoses and treats complex behavioral, developmental or learning disorders in children. (lvhn.org)
  • When you choose a board-certified developmental-behavioral pediatrician at Lehigh Valley Reilly Children's Hospital, you can rest assured your child or teen will receive the highest level of specialty care available. (lvhn.org)
  • There can be hyperactivity with both disorders as well. (myaspergerschild.com)
  • In some cases, your child's challenges may be related to attention-deficit/hyperactivity disorder (ADHD). (lvhn.org)
  • Sensory processing disorders (SPD) are more prevalent in children than autism and as common as attention deficit hyperactivity disorder, yet the condition receives far less attention partly because it's never been recognized as a distinct disease. (ucsf.edu)
  • Pastor PN, Reuben CA. Diagnosed attention deficit hyperactivity disorder and learning disability: United States, 2004-2006. (cdc.gov)
  • Diagnosed attention deficit hyperactivity disorder and learning disability, United States, 2004-2006 : data from the National Health Interview Survey. (cdc.gov)
  • Deficit Disorder with Hyperactivity--epidemiology--United States. (cdc.gov)
  • Other neurological problems that commonly occur in this disorder include seizures, weak muscle tone (hypotonia), movement disorders, and behavioral problems. (medlineplus.gov)
  • Affected patients may have developmental delays or intellectual disability, seizures, autism spectrum disorder or autism-like behaviors and other behavioral challenges. (rarediseases.org)
  • Speech disorders, seizures and autism-like features are some of the most common features observed in patients with SETD1B -NDD. (rarediseases.org)
  • Anti-convulsant medication may control seizures, devices can be inserted in the mouth to assist swallowing, and wheelchairs are often required as the disorder progresses to its final and immobile stage. (levislifelovelaughter.org)
  • Epilepsy is a disorder of the central nervous system often caused by abnormal electrical discharges that develop into seizures. (specialneedsresourceblog.com)
  • However, more subtle and sophisticated techniques, such as voxel-based morphometry studies have allowed researchers to identify bilateral abnormalities in neural volume in areas of the brain associated with motor functions, such as the caudate nucleus, in the affected members of the KE family when compared to the unaffected family members. (wikipedia.org)
  • The affected child will display delayed speech as well as mild facial abnormalities and behavioral issues. (levislifelovelaughter.org)
  • Down's syndrome is accompanied by multisystem pathologies, which involve delays in basic motor skills, motor impairments, and abnormalities in gait and posture 4 . (bvsalud.org)
  • PWS occurs due to abnormalities affecting certain genes in the proximal long arm of chromosome 15 when deleted from the father's chromosome 15 and hence referred to as a genomic imprinting disorder which depends on the sex of the parent donating the chromosome leading to the chromosome defect in the child. (rarediseases.org)
  • As we discover more about ASD and its underlying physiological abnormalities, we learn about new disorders that can also result in ASD. (autismfile.com)
  • Huntington disease (HD) is a progressive, hereditary, neurodegenerative disorder that is characterized by abnormalities in motor skills, cognitive skills, and psychiatric changes. (arupconsult.com)
  • The condition is a communication disorder in which there are difficulties with verbal and written expression. (wikipedia.org)
  • This leads to the degeneration of motor skills and cognitive abilities, as well as behavioral difficulties. (aop-health.com)
  • Our team specializes in treating: Talk to your child's doctor about different If you think your child might have a developmental delay, learn more about Developmental Pediatrics at the Donald A. Gardner Family Center for Developing Minds specializes in evaluating and treating children with developmental difficulties and related behavioral challenges. (expressextension.com)
  • Autism, also known as an autism spectrum disorder (ASD), is a complex condition characterized by communication and behavioral difficulties. (prayatna.co.in)
  • Prader-Willi syndrome (PWS) is a genetic multisystem disorder characterized during infancy by lethargy, diminished muscle tone (hypotonia), a weak suck and feeding difficulties with poor weight gain and growth and other hormone deficiency. (rarediseases.org)
  • It affects the cerebellum and nervous system, which leads to progressive difficulties with walking, balance and coordination, fine motor skills, as well as severe falls in blood pressure when in upright position. (lu.se)
  • One of the most common affected areas is speech, with speech delays and language disorders reported in most patients. (rarediseases.org)
  • Other developmental delays can include delays in gross motor skills, like rolling from back-to-front or front-to-back as an infant, sitting independently, walking or running. (rarediseases.org)
  • These delays can be physical and social, and they may affect communication skills as well. (childrens.com)
  • Understanding gross motor skill acquisition in hospitalized infants with complex medical conditions is necessary to develop and evaluate interventions that may lessen delays. (bvsalud.org)
  • This includes: developmental and language delays, problems in gross motor skills, hypersensitivity to sounds, picky eating, and perseverating. (autism.org)
  • We assess conditions ranging from birth-related complications to motor or language delays, as well as behavioral problems or differences. (childrensnational.org)
  • Many Williams Syndrome patients exhibit autistic behaviors like developmental and language delays, problems with gross motor skills, hypersensitivity to sounds, and picky eating. (prayatna.co.in)
  • Fragile X Syndrome is frequently characterized by behavioral issues and speech-language delays. (prayatna.co.in)
  • Verbal and motor development delays, trouble with learning, feeding issues in babies, snoring issues, skin picking, anger outbursts, and a strong tolerance for pain are some of the behaviors shared by both Prader-Willi syndrome and autism. (prayatna.co.in)
  • When we identify developmental delays early, there is a higher likelihood of preventing long-term problems related to speech and language, motor skills or thinking ability. (lvhn.org)
  • Delays In the onset of treatment result in poorer development In motor. (samplefellow.com)
  • Physical therapists address the most common developmental delays, such as with gross motor skill development (rolling, sitting, crawling, standing and walking), decreased strength, decreased balance, and overall poor coordination in a child. (centerforpediatrictherapy.com)
  • Using blood samples, we might do genetic tests or look for metabolic disorders. (childrens.com)
  • Second, apraxia of speech occurs as a primary or secondary sign in children with complex neurobehavioral disorders (e.g., genetic, metabolic). (asha.org)
  • MLD is also one of a large group of genetic disorders called lysosomal diseases, which are a group of over 70 rare inherited metabolic disorders that result from defects in lysosomal function. (allstripes.com)
  • Individuals with Huntington's are prone to weight loss because it's challenging for them to maintain a healthy weight since they have difficulty with chewing/swallowing/fine motor skills and unknown metabolic problems from the disease. (demystifyingyourhealth.com)
  • There is also a lot of debate about whether specific language impairments, such as expressive language disorder, are caused by deficits in grammar or by a deficit in processing language information. (wikipedia.org)
  • The Procedural Deficit Hypothesis opines that we can explain language impairments due to abnormal development of brain structures that are involved in procedural memory, our memories that remember how to perform different cognitive and motor tasks. (wikipedia.org)
  • Aside from the considerable motor dysfunctions, one will also notice swallowing and speaking impairments in later phases. (aop-health.com)
  • CONTEXT: Studying sensorimotor and neurocognitive impairments in unaffected family members of individuals with autism may help identify familial pathophysiological mechanisms associated with the disorder. (ku.edu)
  • Treatment of CFD with folinic acid (leucovorin calcium), which can enter the brain through the RFC, has been shown in some cases to dramatically improve motor skills, even in as little as one week, as well as improve speech impairments [9]. (autismfile.com)
  • Fragile X syndrome (also known as Martin-Bell syndrome) is a sex-linked genetic disorder. (autism.org)
  • The exact frequency of Fragile X syndrome is unclear, but the CDC estimates that roughly 1.4 in 10,000 males and 0.9 in 10,000 females are affected by this disorder. (autism.org)
  • Approximately 15% to 20% of those with Fragile X Syndrome exhibit autistic-type behaviors, such as poor eye contact, hand-flapping or odd gesture movements, hand-biting, and poor sensory skills. (autism.org)
  • Families are advised to seek genetic counseling to understand the inheritable nature of Fragile X Syndrome and to discuss with family members the likelihood other individuals or future offspring may have this disorder. (autism.org)
  • Fragile X syndrome is a genetic condition that affects males more than females. (prayatna.co.in)
  • The disorder manifests itself in early childhood, varies in severity, and is characterized by impaired social skills, and repetitive behaviors. (prayatna.co.in)
  • Instead, they develop in bits, and as such, a slight change in one subsystem can impact the entire system, leading to different motor behaviors. (eminencepapers.com)
  • Rett syndrome is a neurological disorder affecting primarily females. (prayatna.co.in)
  • Autism is a neurological disorder and a behavioral disorder that acts on the kids, which could be single or multiple. (madhyapradeshmirror.com)
  • Overall, the social, communicative, and behavioral features of childhood disintegrative disorder resemble those of autistic disorder . (medscape.com)
  • Infantile hypotonia, which is often severe, is a near universal feature of the disorder. (rarediseases.org)
  • Hypotonia can also affect motor development in children with ASD. (eminencepapers.com)
  • Delayed motor milestones and suspected motor disabilities 3. (expressextension.com)
  • A delay in reaching language, thinking, social, or motor skills milestones is called developmental delay. (healthline.com)
  • Over time, speech and communication skills decline along with other milestones. (levislifelovelaughter.org)
  • In late-infantile MLD, the first sign is often slowing or regressions of motor skills - often difficulty walking and/or missed milestones. (allstripes.com)
  • Motor milestones and language development are often delayed. (rarediseases.org)
  • Specifically for children, a detailed understanding of normal motor development and gross motor milestones is essential. (centerforpediatrictherapy.com)
  • Underlying muscle tone, joint range of motion, and balance is measured, acquisition of gross motor milestones is assessed, and a parent/child interview is completed. (centerforpediatrictherapy.com)
  • If there are areas of concern with the child's motor patterns, quality of movement or if meeting gross motor milestones falls behind typical expectations, therapy likely will be recommended. (centerforpediatrictherapy.com)
  • This program sees children from birth to 18 years with a variety of developmental issues including developmental language delay, school challenges including ADHD, learning disabilities and school failure, autism spectrum disorder, anxiety disorders, behavioral problems, and more. (expressextension.com)
  • ADHD is a genetic disorder as is ASD. (myaspergerschild.com)
  • One of the reasons SPD has been overlooked until now is that it often occurs in children who also have ADHD or autism, and the disorders have not been listed in the Diagnostic and Statistical Manual used by psychiatrists and psychologists. (ucsf.edu)
  • Several dozen mutations in the GRIN2B gene have been found to cause GRIN2B -related neurodevelopmental disorder, which is characterized by intellectual disability and delayed development of speech and motor skills. (medlineplus.gov)
  • Loss of motor skills, poor muscle tone and problems with balance and walking are more common when onset occurs at a younger age, whereas cognitive issues, intellectual impairment and behavioral problems are more common in adolescence and adulthood forms. (allstripes.com)
  • It is postulated that individuals with intellectual disabilities are how many times more at risk for comorbid or co-occurring disorders than the general population? (nursing-assignments.com)
  • Intellectual disability (ID) becomes apparent during childhood and involves deficits in mental abilities, social skills, and core activities of daily living (ADLs) when compared to same-aged peers. (nursing-assignments.com)
  • Intellectual disability can be genetic or the result of a disorder that interferes with brain development. (msdmanuals.com)
  • People with ID have significantly below average intellectual functioning that is severe enough to limit their ability to cope with one or more areas of normal daily living (adaptive skills) to such a degree that they require ongoing support. (msdmanuals.com)
  • Because of the rapid evolution of genetic testing, additional mutations may be included in newer screening panels. (acog.org)
  • Then, their entire genetic code, all 3.2-billion base pairs , are analyzed for signs of mutations that may be causing a symptom or underlying disorder. (opensourcebiology.eu)
  • in July, researchers at the University of California San Francisco published a study on the use of genetic sequencing to locate mutations that cause Aromatic L-amino acid decarboxylase (AADC) deficiency, a genetic disorder that starves the brain of the dopamine and serotonin required for basic motor and behavioral skills, like holding up one's head or saying hello . (opensourcebiology.eu)
  • MLD is caused by pathogenic variants, also called genetic mutations, in the ARSA or PSAP genes. (allstripes.com)
  • ASH1L with novel private LGD and MIS30 mutations identified in this study (Targeted sequencing identifies 91 neurodevelopmental disorder risk genes with autism and developmental disability biases) and published DN variants indicated in HGVS format. (care4ash1l.com)
  • Due to the vague nature of the diagnosis of expressive language disorder, there is little specific scientific research that we can currently locate. (wikipedia.org)
  • Carrier screening is a term used to describe genetic testing that is performed on an individual who does not have any overt phenotype for a genetic disorder but may have one variant allele within a gene(s) associated with a diagnosis. (acog.org)
  • Any individual who is considering genetic diagnosis should first seek professional support. (aop-health.com)
  • A genetic test called a karyotype analysis can confirm a Turner syndrome diagnosis. (winetourismday.org)
  • Most patients described in the literature have either autism spectrum disorder or autistic features without a formal diagnosis. (rarediseases.org)
  • It is recognized within the medical community that a diagnosis made early in the course of this disorder will render treatment more effective than following a later diagnosis. (levislifelovelaughter.org)
  • While the disorder is life-lasting, individuals with ASD can benefit from early diagnosis, intervention and ongoing therapies to support healthy development. (pmhccares.org)
  • What are the most common co-occurring disorders found that make the diagnosis more complex? (nursing-assignments.com)
  • His motor and cognitive function deteriorated over several years following diagnosis. (medscape.com)
  • Extensive genetic analysis is performed in search of a diagnosis, but more than half of these patients are today left without one. (lu.se)
  • Developmental-behavioral Pediatrics Our location, with state of the art diagnostic and treatment facilities, offers outstanding pediatric services to children in Northwestern Suffolk and Nassau Counties. (expressextension.com)
  • The Division of Development and Behavioral Pediatrics is dedicated to evaluating and treating many different concerns, including: 1. (expressextension.com)
  • Developmental pediatricians (sometimes called Developmental Disabilities and Behavioral Pediatricians) are medical doctors who have completed a residency in pediatrics and have additional subspecialty training in developmental and behavioral pediatrics. (expressextension.com)
  • In 2002, the American Board of Pediatrics began certifying developmental-behavioral pediatricians via a comprehensive examination process. (expressextension.com)
  • Developmental and Behavioral Pediatrics at Children's Hospital of Philadelphia (CHOP) is the largest facility in the tri-state region offering this type of comprehensive care to children. (expressextension.com)
  • Developmental-behavioral pediatricians at Lehigh Valley Reilly Children's Hospital complete medical school as well as an additional three years of training in pediatrics. (lvhn.org)
  • These specialists demonstrate their skill and knowledge by passing a comprehensive exam given by the American Board of Pediatrics. (lvhn.org)
  • NORD gratefully acknowledges Merlin G. Butler, MD, PhD, Director, Division of Research and Genetics, Director, KUMC Genetics Clinic and Professor of Psychiatry & Behavioral Sciences and Pediatrics, University of Kansas Medical Center, for assistance in the preparation of this report. (rarediseases.org)
  • It is the position of ASHA that apraxia of speech exists as a distinct diagnostic type of childhood (pediatric) speech sound disorder that warrants research and clinical services. (asha.org)
  • Childhood apraxia of speech (CAS) is a neurological childhood (pediatric) speech sound disorder in which the precision and consistency of movements underlying speech are impaired in the absence of neuromuscular deficits (e.g., abnormal reflexes, abnormal tone). (asha.org)
  • This mini review aimed to identify the most effective VR systems being used in pediatric rehabilitation and examine the effects of VR on physical activity and motor competence of children with disorders over time. (biomedgrid.com)
  • Future research should expand on the long-term effects of physical activity and motor development among children with disorders as well as the efficacy of different VR systems when pediatric rehabilitation is concerned. (biomedgrid.com)
  • Whether your child requires an autism evaluation, pediatric behavioral therapy, speech therapy, or sensory integration therapy, our staff will be here to help. (centerforpediatrictherapy.com)
  • Reis-Bucklers corneal dystrophy (CDRB) is an autosomal dominant disorder of the superficial corneal stroma that manifests as recurrent corneal erosions in early childhood. (nih.gov)
  • Since a person needs only one copy of the defective gene to develop the disorder, it's an autosomal dominant disorder. (demystifyingyourhealth.com)
  • Researchers are unsure how abnormal activity of NMDA receptors prevents normal growth and development of the brain or why too much or too little activity lead to similar neurological problems in people with GRIN2B -related neurodevelopmental disorder. (medlineplus.gov)
  • This volume reduction showed a high correlation between reduced volume and tests of oral praxis, supporting the idea that odd development of the caudate nucleus is related to the problems in motor control observed in the KE family. (wikipedia.org)
  • Developmental-behavioral pediatricians possess training and experience to consider, in their assessments and treatments, the medical and psychosocial aspects of children's and adolescents' developmental and behavioral problems. (expressextension.com)
  • Medications to control the behavioral problems associated with this disorder have not proven effective. (levislifelovelaughter.org)
  • As well as several major motor disorders when compared to healthy persons 5 , previous studies suggest that children with DS, demonstrate motor problems and cognitive deficits 6 . (bvsalud.org)
  • 10 , one of the main problems for DS individuals is the deficit of the perceptual-motor abilities, which are responsible for the abilities that support the acquisition of several motor skills. (bvsalud.org)
  • The complex of behavioral features reportedly associated with CAS places a child at increased risk for early and persistent problems in speech, expressive language, and the phonological foundations for literacy, and the possible need for augmentative and alternative communication and assistive technology. (asha.org)
  • It often starts with an MRI to look for problems with the brain, followed by formal diagnostic confirmation via a genetic test to look for variants in the ARSA or PSAP genes and/or a test to measure enzyme activity in the blood. (allstripes.com)
  • This research has established a hereditary component of the disorder 7-9 , a number of biochemical markers for problems associated with Irlen Syndrome 10-13 , and differences in brain function for individuals with Irlen Syndrome 14-19, 41 . (irlen.com)
  • Psychotherapy can provide talk therapy to help with behavioral problems, develop coping strategies, manage expectations, and encourage effective communication. (demystifyingyourhealth.com)
  • Establishing a baseline of gross motor abilities and skill development for these infants will guide future research. (bvsalud.org)
  • One possible task that may require perceptual motor abilities and is important for people with DS to adapt to the modern environment is to use the computer as assistive technology. (bvsalud.org)
  • An audiologist specializes in diagnosing and treating disorders of balance and hearing including preventative care, assessment of hearing deficits and need/use of hearing aids. (brooksrehab.org)
  • These changes are the main causes of deficits in perceptual-motor skills responsible for motor skill acquisition and performance of functional activities. (bvsalud.org)
  • Similar oculomotor deficits have been reported in individuals with autism, suggesting that they may be familial and useful for studies of neurophysiological and genetic mechanisms in autism. (ku.edu)
  • When the child is in a social environment, anxiety can deter the child from physical activities, hindering motor development. (eminencepapers.com)
  • Predictive genetic testing is discouraged for asymptomatic minors because a positive result could diminish their autonomy and cause anxiety with no meaningful benefit. (arupconsult.com)
  • Overview of Mental Health Disorders Children and Adolescents Several important mental health disorders, such as depression, anxiety disorders, and eating disorders, often start during childhood and adolescence. (msdmanuals.com)
  • Results showed that VR is useful and efficacious in rehabilitation, especially to children with disorders such as developmental coordination disorder, cerebral palsy, hemiplegia, Down syndrome, and developmental dyspraxia. (biomedgrid.com)
  • Cerebral palsy (CP) is a general term that includes very different clinical manifestations that have in common motor difficulty due to a brain injury. (bvsalud.org)
  • Even though doctors have clear diagnostic guidelines for children with ASD (High-Functioning Autism), some children get misdiagnosed with other disorders. (myaspergerschild.com)
  • This largely explains the introduction of two novel diagnostic categories: Internet gaming disorder in The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition and gaming disorder in The International Classification of Diseases, 11th Revision. (samplefellow.com)
  • Review of the research literature indicates that, at present, there is no validated list of diagnostic features of CAS that differentiates this symptom complex from other types of childhood speech sound disorders, including those primarily due to phonological-level delay or neuromuscular disorder (dysarthria). (asha.org)
  • At the conclusion of the session, the participant will be able to describe Diagnostic and Statistical Manual of Mental Disorders 5th edition , DSM-5 assessment criteria for opioid use disorder, discuss the evidence for opioid use disorder medication assisted treatment with types of medications and settings used in medication assisted therapy. (cdc.gov)
  • At 8 years old, Aiden Shanklin is wheelchair-dependent, has a sensory processing disorder and functions at the level of a 1-and-a-half-year-old. (rwjbh.org)
  • The image shows areas of the brain that can be affected by sensory processing disorders. (ucsf.edu)
  • Sensory processing disorders affect 5 to 16 percent of school-aged children. (ucsf.edu)
  • These brain images, taken with DTI, show water diffusion within the white matter of children with sensory processing disorders. (ucsf.edu)
  • Sensory-motor development is when a child gains the ability to use and coordinate the muscles of their arms, trunk, legs, and even hands. (eminencepapers.com)
  • Children with ASD may face motor challenges because the differences in the brain affect the sensory and motor system and affect the coordination of movement. (eminencepapers.com)
  • Behavioral treatments for these conditions overlap with those of autism. (autism.org)
  • These treatments wholly aim to lessen autism and treat genetic tendencies. (madhyapradeshmirror.com)
  • I'm delighted to welcome you to today's COCA Call "Assessment and Evidence-based Treatments for Opioid Use Disorder. (cdc.gov)
  • Huntington disease (HD) is a genetic, autosomal dominant, neurodegenerative disorder characterized clinically by disorders of movement, progressive dementia, and psychiatric and/or behavioral disturbance. (medscape.com)
  • In the following 128 years, HD has inspired thousands of research papers in which elucidation of this unrelenting neurodegenerative disorder has been attempted. (medscape.com)
  • In looking at the two disorder checklists, it's easy to see that there are similarities and differences. (myaspergerschild.com)
  • It is the eating cause Of cognitive disorders and is associated with mild to moderate learning disabilities. (samplefellow.com)
  • 11] There often are no physical signs of mild forms of ID, although there may be characteristic physical traits when it is associated with a genetic disorder (e.g. (nursing-assignments.com)
  • People with mild ID are capable of learning reading and mathematics skills to approximately the level of a typical child aged nine to twelve. (nursing-assignments.com)
  • For example, a person who has only mild impairment on an intelligence test may have such poor adaptive skills that extensive support is required. (msdmanuals.com)
  • As a result, they often exhibit persistent difficulty with communication and interpersonal skills. (pmhccares.org)
  • Social interactions become compromised (as manifested by aggressiveness, tantrums, or withdrawal from peers), as does motor function, resulting in poor coordination and possible awkwardness of gait. (medscape.com)
  • This skin pigmentation disorder is characterized by dark patches of skin accompanied with severe itching. (targetwoman.com)
  • Patau's syndrome is a serious rare genetic disorder caused by having an additional copy of chromosome 13 in some or all of the body's cells . (winetourismday.org)
  • Hypotrichosis-lymphedema-telangiectasia syndrome is an autosomal recessive disorder characterized by these 3 features, which begin at birth or in early childhood and are progressive (summary by Irrthum et al. (nih.gov)
  • Normal stature and normal head size distinguishes Phelan-McDermid syndrome from other autosomal chromosome disorders. (nih.gov)
  • Williams Syndrome (also known as Williams-Beuren syndrome) is a rare genetics disorder in which a portion of DNA material on chromosome 7 is missing. (autism.org)
  • For more detailed information regarding this disorder please visit the Williams Syndrome Association . (autism.org)
  • computer task, motor learning, Down's syndrome. (bvsalud.org)
  • Subsequently, the PPA syndrome was defined as a disorder limited to progressive aphasia, without general cognitive impairment or dementia, over a 2-year period. (medscape.com)
  • Down syndrome is the most common genetic disorder in children and occurs in I Out Of 600 live births. (samplefellow.com)
  • ASD today encompasses the other previously singled out conditions like pervasive development disorder, Asperger's syndrome, and childhood disintegrative disorder. (eminencepapers.com)
  • Expressive language disorder is one of the "specific developmental disorders of speech and language" recognised by the tenth edition of the International Classification of Diseases (ICD-10). (wikipedia.org)
  • As of the eleventh edition (ICD-11, current 1 January 2022), it is considered to be covered by the various categories of developmental language disorder. (wikipedia.org)
  • According to the National Institute on Deafness and Other Communication Disorders , the most active time for learning speech and language is the first 3 years of life, as the brain develops and matures. (healthline.com)
  • This month is dedicated to raising awareness about communication disorders and the role of Speech-Language Pathologists and Audiologists in providing life-altering treatment. (brooksrehab.org)
  • A Speech-Language Pathologist (SLP) specializes in diagnosing and treating disorders of speech, language and swallowing in individuals of all ages from infancy to the elderly. (brooksrehab.org)
  • The left-lateralized alterations have not been identified in other neuropsychiatric disorders and are of interest given atypical brain lateralization and language development associated with the disorder. (ku.edu)
  • Studies show that the language skills of children with Dc. (samplefellow.com)
  • AIM: This qualitative study explored therapists' use of instructions and feedback when teaching motor tasks to children with developmental coordination disorder (DCD) as a first step in developing practical recommendations. (bvsalud.org)
  • However, current research has yet to reveal a clear-cut pathophysiology for childhood disintegrative disorder, and there remains considerable debate within the developmental disabilities field regarding the long-term outcomes of children with this condition. (medscape.com)
  • Rather, the goals of management are to support young patients in their development and communication skills and ensure families have adequate social supports. (rarediseases.org)
  • Contextual opportunities facilitate skill acquisition, and the interaction between individual and contextual factors is fundamental to enhancing health and social parameters in children with DCD. (bvsalud.org)
  • We know that early intervention can improve learning, communication, social skills and brain development. (pmhccares.org)
  • Home / Shop / Books / Social Sciences / Social and Behavioral Sciences / Psychology / Psychological Methods, Research and Statistics / Psychology Research Summaries. (novapublishers.com)
  • The delay in the neuropsychomotor development is an indication that there are alterations in the acquisition of skills and other development areas 7 . (bvsalud.org)
  • Recent advancements in Virtual Reality (VR) technology has opened a wide array of its practical uses in rehabilitation, physical activity, and motor skill acquisition among children. (biomedgrid.com)
  • Fine motor skills include small movements like holding a toy or using a crayon. (healthline.com)
  • The most sacred skills to humans include eating, thinking and communicating and SLPs treat all three! (brooksrehab.org)
  • Those factors include a genetic component (research shows that most cases involve a genetic link) and increased gestational age. (pmhccares.org)
  • In childhood, features of this disorder include short stature, small genitals and an excessive appetite. (rarediseases.org)
  • Other factors include drug reactions, hormonal changes, genetic factors and medications. (targetwoman.com)
  • It's a spectrum disorder, which means it affects people in different ways and in varying degrees. (webmd.com)
  • This skin pigmentation disorder affects nearly 2% of the population and is more evident in those with darker skin. (targetwoman.com)
  • Autism spectrum disorder (ASD) is a condition that affects brain development, and as a result, the perception and socialization capabilities of the individual are affected. (eminencepapers.com)
  • HD supposedly can cause psychiatric disorders in 2 ways: (1) by the direct action of the gene on striatal neurons, and (2) by the indirect effect of the disordered family environment on the children, regardless of whether they inherited the HD gene. (medscape.com)
  • The PMC is devoting its own research dollars to disproving this, most recently via a paper on rare childhood disorders on a sample of data from the Nicklaus Children's Hospital in Miami. (opensourcebiology.eu)
  • When formulating an appropriate treatment plan, the developmental-behavioral pediatricians at Lehigh Valley Reilly Children's Hospital factor in how developmental, learning or behavioral concerns affect your child, as well as how they affect your entire family. (lvhn.org)
  • What follows is a detailed discussion of some of the more common genetic conditions for which carrier screening is recommended in at least some segments of the population. (acog.org)
  • It is the most common genetic cause of life-threatening childhood obesity. (rarediseases.org)
  • in these patients, speech was affected, and patients lost previously acquired verbal skills or vocabulary. (rarediseases.org)
  • CAS is preferred over alternative terms for this disorder, including developmental apraxia of speech and developmental verbal dyspraxia , which have typically been used to refer only to the idiopathic presentation. (asha.org)
  • Typical motor dysfunctions consist of jerky, involuntary movements of the arms (e.g. finger and hands), the legs, the torso and the face (chorea: Greek for dance). (aop-health.com)