Regenerative Medicine: A field of medicine concerned with developing and using strategies aimed at repair or replacement of damaged, diseased, or metabolically deficient organs, tissues, and cells via TISSUE ENGINEERING; CELL TRANSPLANTATION; and ARTIFICIAL ORGANS and BIOARTIFICIAL ORGANS and tissues.Complementary Therapies: Therapeutic practices which are not currently considered an integral part of conventional allopathic medical practice. They may lack biomedical explanations but as they become better researched some (PHYSICAL THERAPY MODALITIES; DIET; ACUPUNCTURE) become widely accepted whereas others (humors, radium therapy) quietly fade away, yet are important historical footnotes. Therapies are termed as Complementary when used in addition to conventional treatments and as Alternative when used instead of conventional treatment.Medicine, Chinese Traditional: A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.Acupuncture Therapy: Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. It is sometimes used in conjunction with heat, moxibustion, acupressure, or electric stimulation.Tissue Engineering: Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.Genetic Therapy: Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.Embryonic Stem Cells: Cells derived from the BLASTOCYST INNER CELL MASS which forms before implantation in the uterine wall. They retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells.Induced Pluripotent Stem Cells: Cells from adult organisms that have been reprogrammed into a pluripotential state similar to that of EMBRYONIC STEM CELLS.Bioengineering: The application of engineering principles and methods to living organisms or biological systems.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Nuclear Reprogramming: The process that reverts CELL NUCLEI of fully differentiated somatic cells to a pluripotent or totipotent state. This process can be achieved to a certain extent by NUCLEAR TRANSFER TECHNIQUES, such as fusing somatic cell nuclei with enucleated pluripotent embryonic stem cells or enucleated totipotent oocytes. GENE EXPRESSION PROFILING of the fused hybrid cells is used to determine the degree of reprogramming. Dramatic results of nuclear reprogramming include the generation of cloned mammals, such as Dolly the sheep in 1997.Pluripotent Stem Cells: Cells that can give rise to cells of the three different GERM LAYERS.Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Regeneration: The physiological renewal, repair, or replacement of tissue.Tissue Scaffolds: Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.Stem Cell Transplantation: The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.Stem Cells: Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.Stem Cell Research: Experimentation on STEM CELLS and on the use of stem cells.Genetic Vectors: DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.Mesenchymal Stromal Cells: Bone-marrow-derived, non-hematopoietic cells that support HEMATOPOETIC STEM CELLS. They have also been isolated from other organs and tissues such as UMBILICAL CORD BLOOD, umbilical vein subendothelium, and WHARTON JELLY. These cells are considered to be a source of multipotent stem cells because they include subpopulations of mesenchymal stem cells.Cell- and Tissue-Based Therapy: Therapies that involve the TRANSPLANTATION of CELLS or TISSUES developed for the purpose of restoring the function of diseased or dysfunctional cells or tissues.Adult Stem Cells: Cells with high proliferative and self renewal capacities derived from adults.Cell Culture Techniques: Methods for maintaining or growing CELLS in vitro.Gene Transfer Techniques: The introduction of functional (usually cloned) GENES into cells. A variety of techniques and naturally occurring processes are used for the gene transfer such as cell hybridization, LIPOSOMES or microcell-mediated gene transfer, ELECTROPORATION, chromosome-mediated gene transfer, TRANSFECTION, and GENETIC TRANSDUCTION. Gene transfer may result in genetically transformed cells and individual organisms.Hydrogels: Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)Cell Lineage: The developmental history of specific differentiated cell types as traced back to the original STEM CELLS in the embryo.Individualized Medicine: Therapeutic approach tailoring therapy for genetically defined subgroups of patients.Cell Dedifferentiation: A reverse developmental process in which terminally differentiated cells with specialized functions revert back to a less differentiated stage within their own CELL LINEAGE.Multipotent Stem Cells: Specialized stem cells that are committed to give rise to cells that have a particular function; examples are MYOBLASTS; MYELOID PROGENITOR CELLS; and skin stem cells. (Stem Cells: A Primer [Internet]. Bethesda (MD): National Institutes of Health (US); 2000 May [cited 2002 Apr 5]. Available from: http://www.nih.gov/news/stemcell/primer.htm)Cell Transplantation: Transference of cells within an individual, between individuals of the same species, or between individuals of different species.Internal Medicine: A medical specialty concerned with the diagnosis and treatment of diseases of the internal organ systems of adults.Translational Medical Research: The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.Nuclear Medicine: A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds in a pharmaceutical form.Medicine, Traditional: Systems of medicine based on cultural beliefs and practices handed down from generation to generation. The concept includes mystical and magical rituals (SPIRITUAL THERAPIES); PHYTOTHERAPY; and other treatments which may not be explained by modern medicine.Cell Engineering: Methods and techniques used to modify or select cells and develop conditions for growing cells for biosynthetic production of molecules (METABOLIC ENGINEERING), for generation of tissue structures and organs in vitro (TISSUE ENGINEERING), or for other BIOENGINEERING research objectives.Medicine, Kampo: System of herbal medicine practiced in Japan by both herbalists and practitioners of modern medicine. Kampo originated in China and is based on Chinese herbal medicine (MEDICINE, CHINESE TRADITIONAL).Mesenchymal Stem Cell Transplantation: Transfer of MESENCHYMAL STEM CELLS between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS).Lentivirus: A genus of the family RETROVIRIDAE consisting of non-oncogenic retroviruses that produce multi-organ diseases characterized by long incubation periods and persistent infection. Lentiviruses are unique in that they contain open reading frames (ORFs) between the pol and env genes and in the 3' env region. Five serogroups are recognized, reflecting the mammalian hosts with which they are associated. HIV-1 is the type species.Octamer Transcription Factor-3: An octamer transcription factor that is expressed primarily in totipotent embryonic STEM CELLS and GERM CELLS and is down-regulated during CELL DIFFERENTIATION.Transduction, Genetic: The transfer of bacterial DNA by phages from an infected bacterium to another bacterium. This also refers to the transfer of genes into eukaryotic cells by viruses. This naturally occurring process is routinely employed as a GENE TRANSFER TECHNIQUE.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Medicine: The art and science of studying, performing research on, preventing, diagnosing, and treating disease, as well as the maintenance of health.Halcinonide: A glucocorticoid used topically in the treatment of DERMATITIS; ECZEMA; or PSORIASIS. It may cause skin irritation.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Guided Tissue Regeneration: Procedures for enhancing and directing tissue repair and renewal processes, such as BONE REGENERATION; NERVE REGENERATION; etc. They involve surgically implanting growth conducive tracks or conduits (TISSUE SCAFFOLDING) at the damaged site to stimulate and control the location of cell repopulation. The tracks or conduits are made from synthetic and/or natural materials and may include support cells and induction factors for CELL GROWTH PROCESSES; or CELL MIGRATION.Adenoviridae: A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.Osteogenesis: The process of bone formation. Histogenesis of bone including ossification.Nanofibers: Submicron-sized fibers with diameters typically between 50 and 500 nanometers. The very small dimension of these fibers can generate a high surface area to volume ratio, which makes them potential candidates for various biomedical and other applications.Bone Regeneration: Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.Biomimetics: An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS.Biomimetic Materials: Materials fabricated by BIOMIMETICS techniques, i.e., based on natural processes found in biological systems.Cellular Microenvironment: Local surroundings with which cells interact by processing various chemical and physical signals, and by contributing their own effects to this environment.Cell SeparationTransgenes: Genes that are introduced into an organism using GENE TRANSFER TECHNIQUES.Feeder Cells: Cells used in COCULTURE TECHNIQUES which support the growth of the other cells in the culture. Feeder cells provide auxillary substances including attachment substrates, nutrients, or other factors that are needed for growth in culture.Hydrogel: A network of cross-linked hydrophilic macromolecules used in biomedical applications.History of MedicineExtracellular Matrix: A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.Dependovirus: A genus of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, which are dependent on a coinfection with helper adenoviruses or herpesviruses for their efficient replication. The type species is Adeno-associated virus 2.Clinical Medicine: The study and practice of medicine by direct examination of the patient.Stem Cell Niche: A particular zone of tissue composed of a specialized microenvironment where stem cells are retained in a undifferentiated, self-renewable state.Drugs, Chinese Herbal: Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.AlchemyTransplants: Organs, tissues, or cells taken from the body for grafting into another area of the same body or into another individual.Cell Transdifferentiation: A naturally occurring phenomenon where terminally differentiated cells dedifferentiate to the point where they can switch CELL LINEAGES. The cells then differentiate into other cell types.Nanostructures: Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.Emergency Medicine: The branch of medicine concerned with the evaluation and initial treatment of urgent and emergent medical problems, such as those caused by accidents, trauma, sudden illness, poisoning, or disasters. Emergency medical care can be provided at the hospital or at sites outside the medical facility.Teratoma: A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)Evidence-Based Medicine: An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)SOXB1 Transcription Factors: A subclass of SOX transcription factors that are expressed in neuronal tissue where they may play a role in the regulation of CELL DIFFERENTIATION. Members of this subclass are generally considered to be transcriptional activators.Adipogenesis: The differentiation of pre-adipocytes into mature ADIPOCYTES.Medicine, Ayurvedic: The traditional Hindu system of medicine which is based on customs, beliefs, and practices of the Hindu culture. Ayurveda means "the science of Life": veda - science, ayur - life.History, 21st Century: Time period from 2001 through 2100 of the common era.Electromagnetic Radiation: Waves of oscillating electric and MAGNETIC FIELDS which move at right angles to each other and outward from the source.History, 20th Century: Time period from 1901 through 2000 of the common era.Dental Pulp: A richly vascularized and innervated connective tissue of mesodermal origin, contained in the central cavity of a tooth and delimited by the dentin, and having formative, nutritive, sensory, and protective functions. (Jablonski, Dictionary of Dentistry, 1992)Bioartificial Organs: Artificial organs that are composites of biomaterials and cells. The biomaterial can act as a membrane (container) as in BIOARTIFICIAL LIVER or a scaffold as in bioartificial skin.Chondrogenesis: The formation of cartilage. This process is directed by CHONDROCYTES which continually divide and lay down matrix during development. It is sometimes a precursor to OSTEOGENESIS.Teratology: A branch of embryology for the study of congenital malformations and developmental abnormalities.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Lipectomy: Removal of localized SUBCUTANEOUS FAT deposits by SUCTION CURETTAGE or blunt CANNULATION in the cosmetic correction of OBESITY and other esthetic contour defects.Neural Stem Cells: Self-renewing cells that generate the main phenotypes of the nervous system in both the embryo and adult. Neural stem cells are precursors to both NEURONS and NEUROGLIA.Integrative Medicine: The discipline concerned with using the combination of conventional ALLOPATHIC MEDICINE and ALTERNATIVE MEDICINE to address the biological, psychological, social, and spiritual aspects of health and illness.Bone Marrow Cells: Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.Embryo Research: Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus during the prenatal stage of development that is characterized by rapid morphological changes and the differentiation of basic structures. In humans, this includes the period from the time of fertilization to the end of the eighth week after fertilization.Mechanical Phenomena: The properties and processes of materials that affect their behavior under force.Osteopathic Medicine: A medical discipline that is based on the philosophy that all body systems are interrelated and dependent upon one another for good health. This philosophy, developed in 1874 by Dr. Andrew Taylor Still, recognizes the concept of "wellness" and the importance of treating illness within the context of the whole body. Special attention is placed on the MUSCULOSKELETAL SYSTEM.Microtechnology: Manufacturing technology for making microscopic devices in the micrometer range (typically 1-100 micrometers), such as integrated circuits or MEMS. The process usually involves replication and parallel fabrication of hundreds or millions of identical structures using various thin film deposition techniques and carried out in environmentally-controlled clean rooms.Wound Healing: Restoration of integrity to traumatized tissue.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Embryo, Mammalian: The entity of a developing mammal (MAMMALS), generally from the cleavage of a ZYGOTE to the end of embryonic differentiation of basic structures. For the human embryo, this represents the first two months of intrauterine development preceding the stages of the FETUS.Rejuvenation: The phenomenon of youthfulness, vitality, and freshness being restored. This can apply to appearance, TISSUES, organ functions, or other areas.Dental Papilla: Mesodermal tissue enclosed in the invaginated portion of the epithelial enamel organ and giving rise to the dentin and pulp.Fluocinonide: A topical glucocorticoid used in the treatment of ECZEMA.Developmental Biology: The field of biology which deals with the process of the growth and differentiation of an organism.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Porosity: Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.Embryoid Bodies: Spontaneous aggregations of human embryonic stem cells that occur in vitro after culturing in a medium that lacks LEUKEMIC INHIBITORY FACTOR. The embryoid bodies can further differentiate into cells that represent different lineages.Sports Medicine: The field of medicine concerned with physical fitness and the diagnosis and treatment of injuries sustained in exercise and sports activities.Polyglycolic Acid: A biocompatible polymer used as a surgical suture material.Cell Shape: The quality of surface form or outline of CELLS.Hematopoietic Stem Cells: Progenitor cells from which all blood cells derive.Tooth Exfoliation: Physiologic loss of the primary dentition. (Zwemer, Boucher's Clinical Dental Terminology, 4th ed)Neovascularization, Physiologic: The development of new BLOOD VESSELS during the restoration of BLOOD CIRCULATION during the healing process.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Totipotent Stem Cells: Single cells that have the potential to form an entire organism. They have the capacity to specialize into extraembryonic membranes and tissues, the embryo, and all postembryonic tissues and organs. (Stem Cells: A Primer [Internet]. Bethesda (MD): National Institutes of Health (US); 2000 May [cited 2002 Apr 5]. Available from: http://www.nih.gov/news/stemcell/primer.htm)Mice, SCID: Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.Internship and Residency: Programs of training in medicine and medical specialties offered by hospitals for graduates of medicine to meet the requirements established by accrediting authorities.Genes, Transgenic, Suicide: Genes that are used transgenically, i.e., via GENE TRANSFER TECHNIQUES to induce CELL DEATH.Medicine, African Traditional: A system of traditional medicine which is based on the beliefs and practices of the African peoples. It includes treatment by medicinal plants and other materia medica as well as by the ministrations of diviners, medicine men, witch doctors, and sorcerers.Silk: A continuous protein fiber consisting primarily of FIBROINS. It is synthesized by a variety of INSECTS and ARACHNIDS.Artificial Organs: Devices intended to replace non-functioning organs. They may be temporary or permanent. Since they are intended always to function as the natural organs they are replacing, they should be differentiated from PROSTHESES AND IMPLANTS and specific types of prostheses which, though also replacements for body parts, are frequently cosmetic (EYE, ARTIFICIAL) as well as functional (ARTIFICIAL LIMBS).Alginates: Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.Biomedical Engineering: Application of principles and practices of engineering science to biomedical research and health care.Germ Layers: The three primary germinal layers (ECTODERM; ENDODERM; and MESODERM) developed during GASTRULATION that provide tissues and body plan of a mature organism. They derive from two early layers, hypoblast and epiblast.Gelatin: A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food adjuvant, plasma substitute, hemostatic, suspending agent in pharmaceutical preparations, and in the manufacturing of capsules and suppositories.Physical and Rehabilitation Medicine: A medical specialty concerned with the use of physical agents, mechanical apparatus, and manipulation in rehabilitating physically diseased or injured patients.Genetic Engineering: Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc.Occupational Medicine: Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings.Hexuronic Acids: Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.Platelet-Rich Plasma: A preparation consisting of PLATELETS concentrated in a limited volume of PLASMA. This is used in various surgical tissue regeneration procedures where the GROWTH FACTORS in the platelets enhance wound healing and regeneration.Cloning, Organism: The formation of one or more genetically identical organisms derived by vegetative reproduction from a single cell. The source nuclear material can be embryo-derived, fetus-derived, or taken from an adult somatic cell.Glucuronic Acid: A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.Epigenesis, Genetic: A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.Immunomodulation: Alteration of the immune system or of an immune response by agents that activate or suppress its function. This can include IMMUNIZATION or administration of immunomodulatory drugs. Immunomodulation can also encompass non-therapeutic alteration of the immune system effected by endogenous or exogenous substances.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Tooth: One of a set of bone-like structures in the mouth used for biting and chewing.Green Fluorescent Proteins: Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Retroviridae: Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES).Implants, Experimental: Artificial substitutes for body parts and materials inserted into organisms during experimental studies.Veterinary Medicine: The medical science concerned with the prevention, diagnosis, and treatment of diseases in animals.Phytotherapy: Use of plants or herbs to treat diseases or to alleviate pain.Gastroenterology: A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).Mice, Inbred C57BLModels, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Endothelial Cells: Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.Polymerization: Chemical reaction in which monomeric components are combined to form POLYMERS (e.g., POLYMETHYLMETHACRYLATE).Liver, Artificial: Devices for simulating the activities of the liver. They often consist of a hybrid between both biological and artificial materials.Drug Discovery: The process of finding chemicals for potential therapeutic use.Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).National Library of Medicine (U.S.): An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.Hepatocytes: The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.Thymidine Kinase: An enzyme that catalyzes the conversion of ATP and thymidine to ADP and thymidine 5'-phosphate. Deoxyuridine can also act as an acceptor and dGTP as a donor. (From Enzyme Nomenclature, 1992) EC 188.8.131.52.Forecasting: The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Sus scrofa: A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Ganciclovir: An ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.Adipose Tissue: Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.Collagen: A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).Bone Diseases: Diseases of BONES.Mice, Nude: Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.Hair Follicle: A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.Drugs, Essential: Drugs considered essential to meet the health needs of a population as well as to control drug costs.Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Nanotechnology: The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.Environmental Medicine: Medical specialty concerned with environmental factors that may impinge upon human disease, and development of methods for the detection, prevention, and control of environmentally related disease.Medicine, Korean Traditional: Medical practice or discipline that is based on the knowledge, cultures, and beliefs of the people of KOREA.Endoderm: The inner of the three germ layers of an embryo.Periodontium: The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Amniotic Fluid: A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS).Bioreactors: Tools or devices for generating products using the synthetic or chemical conversion capacity of a biological system. They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. For production of proteins or enzymes, recombinant microorganisms such as bacteria, mammalian cells, or insect or plant cells are usually chosen.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Alkaline Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 184.108.40.206.Elastic Modulus: Numerical expression indicating the measure of stiffness in a material. It is defined by the ratio of stress in a unit area of substance to the resulting deformation (strain). This allows the behavior of a material under load (such as bone) to be calculated.Schools, Medical: Educational institutions for individuals specializing in the field of medicine.Community Medicine: A branch of medicine concerned with the total health of the individual within the home environment and in the community, and with the application of comprehensive care to the prevention and treatment of illness in the entire community.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Polyesters: Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.Osteoblasts: Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.Amnion: The innermost membranous sac that surrounds and protects the developing embryo which is bathed in the AMNIOTIC FLUID. Amnion cells are secretory EPITHELIAL CELLS and contribute to the amniotic fluid.Microfluidic Analytical Techniques: Methods utilizing the principles of MICROFLUIDICS for sample handling, reagent mixing, and separation and detection of specific components in fluids.Bone Morphogenetic Protein 2: A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into OSTEOBLASTS.Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Fetal Blood: Blood of the fetus. Exchange of nutrients and waste between the fetal and maternal blood occurs via the PLACENTA. The cord blood is blood contained in the umbilical vessels (UMBILICAL CORD) at the time of delivery.Chondrocytes: Polymorphic cells that form cartilage.Tropical Medicine: The branch of medicine concerned with diseases, mainly of parasitic origin, common in tropical and subtropical regions.Education, Medical: Use for general articles concerning medical education.Parthenogenesis: A unisexual reproduction without the fusion of a male and a female gamete (FERTILIZATION). In parthenogenesis, an individual is formed from an unfertilized OVUM that did not complete MEIOSIS. Parthenogenesis occurs in nature and can be artificially induced.Osteocytes: Mature osteoblasts that have become embedded in the BONE MATRIX. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi.Nanoparticles: Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.Coculture Techniques: A technique of culturing mixed cell types in vitro to allow their synergistic or antagonistic interactions, such as on CELL DIFFERENTIATION or APOPTOSIS. Coculture can be of different types of cells, tissues, or organs from normal or disease states.Curriculum: A course of study offered by an educational institution.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Cell Adhesion: Adherence of cells to surfaces or to other cells.Polyethylene Glycols: Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.Social Medicine: A branch of medicine concerned with the role of socio-environmental factors in the occurrence, prevention and treatment of disease.
Jocelyn Kaiser (2005). "Gene therapy. Putting the fingers on gene repair". Science. 310 (5756): 1894-6. doi:10.1126/science. ... Stem cell regenerative medicine uses three different strategies: Implantation of stem cells from culture into an existing ... This was one of the first medically accepted rejuvenation therapies (before he was proved to be wrong around 1930-1940). The ... For cancer (the most lethal consequence of mutations) the strategy is to use gene therapy to delete the genes for telomerase ...
National Institute of Arthritis and Musculoskeletal and Skin Diseases
... bone and cartilage transplantation and gene therapy. Tissue engineering, regenerative medicine, sports medicine and ... programs emphasize the application of fundamental knowledge of bone cell biology to the development of drug and gene therapies ... The program operates a Laboratory of Regenerative Medicine and a Laboratory of Oral Connective Tissue Biology. NIAMS scientists ... A major focus is the study of receptor-mediated signal transduction and how these processes link to the regulation of genes ...
Rao was also the VP of Regenerative Medicine at Life Technologies. Additionally, he co-founded Q Therapeutics, a stem-cell ... research firm and serves on USDA Cellular Tissue and Gene Therapies advisory committee and more. Rao also holds a joint ... Rao, Mahendra S. (2011). "Funding Translational Work in Cell-Based Therapy". Cell Stem Cell. 9 (1): 7-10. doi:10.1016/j.stem. ... In 2011, Rao was appointed Director of the National Institutes of Health Center for Regenerative Medicine. Rao received his ...
... including gene therapy and regenerative medicine, are the National Institute of Neurological Disorders and Stroke, National ... Present and Future in Relation to Implementing Therapies". The Clinical Biochemist Reviews. 32 (3): 129-134. ISSN 0159-8090. ... occupational therapy, orthotic intervention (e.g., ankle-foot orthosis), speech therapy, and respiratory therapy may be helpful ... The word "dystrophy" is from the Greek dys, meaning "difficult" and troph meaning "nourish". Gene therapy, as a treatment, is ...
... regenerative medicine, molecular repair, gene therapy, pharmaceuticals, and organ replacement (such as with artificial organs ... The anti-aging industry offers several hormone therapies. Some of these have been criticized for possible dangers and a lack of ... Rattan, S. I. S.; Singh, R. (2008-10-22). "Progress & Prospects: Gene therapy in aging". Gene Therapy. 16 (3-9): 3-9. doi: ... 2015). Cellular senescence in aging and age-related disease: from mechanisms to therapy Nature Medicine doi:10.1038/nm.4000 ...
Nolta's research focuses on human stem cells and regenerative medicine therapies. Nolta's work focuses primarily on ... After serving as Scientific Director of the Cell Processing and Gene Therapy Good Manufacturing Practice facility at Washington ... Nolta is known for her work with stem cell-related regenerative medicine. Nolta's current research focuses on treatment of ... Nolta was hired by Donald Kohn at the Children's Hospital Los Angeles and worked on gene therapy procedures. Nolta now serves ...
For example, clinical trials began in February 2014 to use gene therapy to treat Leber hereditary optic neuropathy, which is ... National Institutes of Health is to use the visual system as a window to understand neural plasticity and regenerative medicine ... and novel therapies are emerging to treat traditionally vision-devastating disease. ... preparation for gene therapy clinical trial". JAMA ophthalmology. 132 (4): 428-36. doi:10.1001/jamaophthalmol.2013.7971. PMC ...
Leonard M. Miller School of Medicine
Stem Cell Institute seeks to understand the biology of stem cells and translate basic research into new regenerative therapies ... In 2012, U.S. News & World Report ranked the University of Miami Physical Therapy Department 9th in the nation. In 2017, U.S. ... The center has identified a family of genes that may control the ability of the optic nerve to regenerate. The Miller Medical ... University of Miami Leonard M. Miller School of Medicine University of Miami Miller School of Medicine Internal Medicine ...
... potential applicability in cell replacement therapy and regenerative medicine". Frontiers in Bioscience. 12 (8-12): 4525-35. ... The chromatin of iPSCs appears to be more "closed" or methylated than that of ESCs. Similarly, the gene expression ... Hanna V, Gassei K, Orwig KE (2015). "Stem Cell Therapies for Male Infertility: Where Are We Now and Where Are We Going?". ... Gurtner GC, Callaghan MJ, Longaker MT (2007). "Progress and potential for regenerative medicine". Annual Review of Medicine. 58 ...
On December 21, the company announced it would acquire LifeCell Corp., a specialist in regenerative medicine, for $2.9 billion ... gaining the positive photosensitivity gene therapy treatment, RST-001. RST-001 is to be used in retinas in which rod and cone ... "Allergan Partners with Rugen to Develop ASD, OCD Therapies". GEN. 25 November 2015. Retrieved 27 November 2015. Rockoff, ... US General Medicine (containing - CNS, Cardiovascular, GI, Women's health, anti-infectives and urology) and International. The ...
Induced stem cells
Pan, G.; Wang, T.; Yao, H.; Pei, D. (2012). "Somatic cell reprogramming for regenerative medicine: SCNT vs. IPS cells". ... Dhodapkar, M. V.; Dhodapkar, K. M. (2011). "Spontaneous and therapy-induced immunity to pluripotency genes in humans: Clinical ... It has potential for in vitro scale-up, enabling MSC-based therapies. MSC derived from iPSC have the capacity to aid ... Such reprogramming of somatic cells to a pluripotent state holds huge potentials for regenerative medicine. Unfortunately, the ...
Further research into this technique should have potential benefits to gene therapy, blood transfusion, and topical medicine. ... "NPJ Regenerative Medicine. 2: 33. doi:10.1038/s41536-017-0036-x. PMC 5736713. PMID 29302366.. ... Bone marrow transplant is the most widely used stem-cell therapy, but some therapies derived from umbilical cord blood are also ... European Medicines Agency. "First stem-cell therapy recommended for approval in EU". Retrieved 12 December 2014.. ...
... "regenerative medicine" in the way that it is used today: "an approach to therapy that ... employs human genes, proteins and ... had the potential to develop into a new kind of regenerative therapy. Explaining the new class of therapies that such cells ... Regenerative Medicine. 3 (1): 1-5. doi:10.2217/174607220.127.116.11. PMID 18154457. "Regenerative medicine glossary". Regenerative ... Regenerative Medicine, 2008, 3(1), 1-5  "UM Leads in the Field of Regenerative Medicine: Moving from Treatments to Cures - ...
Eugene, Marty. "Dr. Farshchian: The Center for regenerative medicine introduces Genorthix system". prweb.com. PR Web. Retrieved ... One of the letters included a package that began Jackson detoxification therapy. In March 2003, Jackson and Farshchian zeroed ... His results have demonstrated the effectiveness of the additional, non-traditional therapies for many patients. Farshchian is ... He is director of The Center for Regenerative Medicine, which he founded in 2000 in order to pursue pioneering regimens in the ...
Brian Hanley (microbiologist)
"Gene Therapy AMAScience Ama Series: Hi Reddit! I'm Brian Hanley, PhD and CEO of Butterfly Sciences. I work on gene therapies ( ... He submitted his protocol to a private institutional review board (IRB), the Institute of Regenerative and Cellular Medicine in ... "GHRH plasmid gene therapy for aging". Retrieved 13 November 2017. Regalado, Antonio. "One man's quest to hack his own genes". ... He is known for using an experimental gene therapy to try to improve health span, and is the first subject in the study. Hanley ...
... the first targeted therapy for chronic myelogenous leukemia. Witte also co-discovered the gene for Bruton's tyrosine kinase, a ... founding director of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, and the UC Regents' ... the stem cells for epithelial cancers of the prostate and other organs in order to define new and more targeted therapies. ... He is a distinguished professor of microbiology, immunology and molecular genetics in the David Geffen School of Medicine at ...
Sel tunjang Bahasa Melayu, ensiklopedia bebas
"Progress and potential for regenerative medicine". Annu. Rev. Med. 58: 299-312. 2007. doi:10.1146/annurev.med.58.082405.095329 ... "Gene therapy is first deafness 'cure'". New Scientist. February 14, 2005.. *^ "Stem cells used to restore vision". BBC News.. ... "Stem Cell Therapies for Male Infertility: Where Are We Now and Where Are We Going?". Biennial Review of Infertility. 2015.. ...
This led the way to treatments for other genetic diseases and increased interest in germ line gene therapy - therapy affecting ... as cited in Gurtner GC; Callaghan MJ; Longaker MT (2007). "Progress and potential for regenerative medicine". Annu. Rev. Med. ... to encourage the development of new life extension therapies in mice, which are genetically similar to humans. So far, three ... "Gene Therapy Clinical Trials Worldwide". www.wiley.com. Retrieved 28 May 2017. "Approval Letter - Provenge". Food and Drug ...
Further research into this technique should have potential benefits to gene therapy, blood transfusion, and topical medicine. ... Bone marrow transplant is the most widely used stem-cell therapy, but some therapies derived from umbilical cord blood are also ... Most stem cells intended for regenerative therapy are generally isolated either from the patient's bone marrow or from adipose ... European Medicines Agency. "First stem-cell therapy recommended for approval in EU". Retrieved 12 December 2014. Maguire, G (12 ...
She is the director of the Center for Regenerative Medicine and professor at the Scripps Research Institute in La Jolla, ... Multiple sclerosis therapy development Loring is developing a cell based therapy for multiple sclerosis. Along with ... Loring oversaw the development of PluriTest, an animal-free, molecular test of pluripotency which uses gene expression array ... invited to join the prestigious international group of researchers working toward development of cell replacement therapies for ...
Regenerative medicine. 6 (3): 265-72. doi:10.2217/rme.11.28. PMID 21548728. "Allogeneic Stem Cell Transplant". WebMD. Retrieved ... Van Der Berg DJ, Sharma AK, Bruno E, Hoffman R (1998). "Role of members of the Wnt gene family in human hematopoiesis". Blood. ... Mays, RW; Van't Hof, W; Ting, AE; Perry, R; Deans, R (2007). "Development of adult pluripotent stem cell therapies for ischemic ... The experimental field of Stem cell therapy has shown promise for new types of treatment. In mainstream medicine, cell therapy ...
Hati bahasa Indonesia, ensiklopedia bebas
"Division of Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka University Graduate School of Medicine; Kim WH ... "The Goldyne Savad Institute for Gene Therapy, Hadassah Hebrew University Hospital,; Galun E, Axelrod JH. Diakses tanggal 2010- ... "The role of cytokines in liver failure and regeneration: potential new molecular therapies". ... "Stem Cell and Regenerative Medicine Lab, Beijing Institute of Transfusion Medicine; Zhou J, Zhao L, Qin L, Wang J, Jia Y, Yao H ...
Cilmes šūna - Vikipēdija
"Journal of Stem Cells and Regenerative Medicine.. *↑ "Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal ... Gene therapy is first deafness 'cure'». New Scientist. 2005. gada 14. februāris. ... "Stem Cell Therapies for Male Infertility: Where Are We Now and Where Are We Going?". Biennial Review of Infertility. 2015. Bone ... "Progress and potential for regenerative medicine". Annu. Rev. Med. 58: 299-312. 2007. doi:10.1146/annurev.med.58.082405.095329 ...
Abeona Receives FDA Regenerative Medicine Advanced Therapy Designation for EB-101 Gene Therapy in Epidermolysis Bullosa |...
NASDAQ:ABEO), a leading clinical-stage biopharmaceutical company focused on developing novel cell and gene therapies for life- ... has granted the Regenerative Medicine Advanced Therapy (RMAT) designation to EB-101, the Companys gene-corrected autologous ... EB-101 is an autologous gene-corrected cell therapy approach that utilizes a patients own cells and genetically re-engineers ... First gene therapy RMAT designation for Epidermolysis Bullosa Enables accelerated approval path and real world data usage NEW ...
The Alliance for Regenerative Medicine Releases Agenda for Fifth Annual Cell & Gene Therapy Investor Day
Gene Therapy Investor Day, taking place April 27, 2017 in Boston, MA. This event, co-hosted by Piper Jaffray and held in ... The Alliance for Regenerative Medicine (ARM) today released the complete agenda for its upcoming fifth annual Cell & ... and held in partnership with Cowen and Company is the only investor conference specifically focused on cell and gene therapies ... The Alliance for Regenerative Medicine Releases Agenda for Fifth Annual Cell & Gene Therapy Investor Day ...
Biomaterials for Cell Delivery: Vehicles in Regenerative Medicine, 1st Edition (Hardback) - Routledge
... key strategies and recent accomplishments in the area of developing cell/biomaterial constructs for regenerative medicine. The ... Gene and Cell Therapy. Learn more…. Subject Categories. *Physical Sciences*Materials Science*Biomaterials ... Natural materials for cell-based therapies. Synthetic polymers for cell-based therapies. Decellularized tissues for ... key strategies and recent accomplishments in the area of developing cell/biomaterial constructs for regenerative medicine. The ...
Regenerative medicine : The Niche
Can gene therapy plus liver "stem cells" cure diabetes?. Posted by Monya Baker , Categories: Regenerative medicine ... Regenerative medicine. Heres a trio of three early stage studies that look encouraging for using stem cells as therapies in ... Gene therapy combined with reprogramming makes disease-free cells. Posted by Monya Baker , Categories: Regenerative medicine ... Posted by Monya Baker , Categories: Regenerative medicine. One of the leading cell-therapy diabetes companies has just enlisted ...
Hamon Center for Regenerative Science and Medicine - UT Southwestern, Dallas, Texas
The Hamon Center for Regenerative Science and Medicine seeks to understand the basis of organ formation to develop therapies ... Presidents Lecture Series: "Gene Therapy and Gene Editing: New Hope for Rare Diseases". February 28, 2019. ... of scientists and clinicians who will develop this new scientific knowledge and translate it into novel human therapies ... 2019-2020 Regenerative Medicine Seminar Series. September 6, 2019. The Hamon Center for Regenerative Science and Medicine is ...
... of operations for the universitys leading scientists and clinical faculty working to develop regenerative medicine therapies. ... stem cell therapy, medical devices and other techniques to repair damaged or diseased tissues and organs. The University of ... Pittsburgh School of Medicine and UPMC Health System have established the McGowan Institute for Regenerative Medicine which ... enables cutting-edge basic and clinical research to be performed across disciplines allowing rapid development of therapies and ...
Planning for Commercial Scale of Cell Therapy and Regenerative Medicine Products, Part 1BioProcess International
Crucial to cell therapy manufacturing success is developing a plan early to understand how and when to address challenges for a ... CDMO Celonic jumping into cell & gene therapies with €50m plant. *. BioProcess Insider. Biocon going digital to fix insulin ... Since early 2004, my company has worked with organizations dedicated to cell therapy and regenerative medicine to help them ... Much mystique and mystery surround the emerging industries of cell therapy and regenerative medicine. As companies progress ...
Cell & Gene Therapy, and Regenerative Medicine - Different Definitions | Cell & Gene Therapy Insights
Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market. *Automation of Cell and Gene Therapy Manufacturing: ... Cell & Gene Therapy, and Regenerative Medicine - Different Definitions. In by 6th July 2016. ... Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market. *Automation of Cell and Gene Therapy Manufacturing: ... The Cell & Gene Therapy Manufacturing Pathway: Part 3. *Automation and single-use systems in cell & gene therapy manufacture: ...
Reportlinker Adds Regenerative Medicines: Bone and Joint Applications
Regenerative Medicines: Bone and Joint Applications http://www.reportlinker.com/p ... GENE THERAPY 27 Gene Therapy Trials Targeting Bone and Joint Diseases and Disorders 28 BIOREACTOR USE IN REGENERATIVE MEDICINE ... Chapter-6: STEM CELL THERAPIES AND REGENERATIVE MEDICINE STEM CELLS AS POTENTIAL REPLACEMENT CELLS 49 TECHNICAL IMPEDIMENTS 50 ... BARRIERS TO REGENERATIVE MEDICINE 11 CURRENT R&D PRIORITIES 12 TABLE 2 PRINCIPAL REGENERATIVE MEDICINE BUSINESS R&D FOCUSES 13 ...
Clinical Trials and Research in Cell & Gene Therapies
10th International Conference on Tissue Science and Regenerative Medicine. , Radisson, Narita , Tokyo, Japan ... Clinical Trials and Research in Cell & Gene Therapies. *Principles of gene therapy & clinical gene therapy ... 2nd International Conference and Exhibition on Cell & Gene Therapy October 23-25, 2013 Holiday Inn Orlando International ... Related Conference of Clinical Trials and Research in Cell & Gene Therapies. January 28-29, 2019 ...
25 Million funding for Ontario Institute for Regenerative Medicine | Cell & Gene Therapy Insights
Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market. *Automation of Cell and Gene Therapy Manufacturing: ... Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market. *Automation of Cell and Gene Therapy Manufacturing: ... The Cell & Gene Therapy Manufacturing Pathway: Part 3. *Automation and single-use systems in cell & gene therapy manufacture: ... The Cell & Gene Therapy Manufacturing Pathway: Part 3. *Automation and single-use systems in cell & gene therapy manufacture: ...
2nd Global Conference on Tissue Engineering and Regenerative Medicine, Stem Cell Research(CSE) Tickets, Mon, Mar 25, 2019 at 8...
New York Events List presents 2nd Global Conference on Tissue Engineering and Regenerative Medicine, Stem Cell Research(CSE) - ... Tissue designing methodologies has included cell and Gene Therapy.. 3D Bio-printing Techniques. The 3D Bio-printing uses ... regenerative capacity in comparison with lower vertebrates.This review will first discuss regenerative medicine therapies that ... Tissue Engineering and Regenerative Medicine, Stem Cell Research. About. Tissue Engineering and Regenerative Medicine, Stem ...
Gene Therapy, PTC Therapeutics. Michael Lehmicke, Director, Science And Industry Affairs, Alliance for Regenerative Medicine. ... Advanced Therapies Clinical Development * Advanced Therapies Manufacturing * Advanced Therapies Commercialization * Digital ... Pediatric Gene Therapy And Medical Ethics Working Group, Assistant Professor Of Psychiatry, Icahn School Of Medicine, The Mount ... Weiyong Sun, Senior Director, Specialty Medicine Search, Evaluation And Global Business Development, Daiichi Sankyo Co Ltd. ...
Developments in Tissue Engineered and Regenerative Medicine Products - 1st Edition
Purchase Developments in Tissue Engineered and Regenerative Medicine Products - 1st Edition. Print Book & E-Book. ISBN ... He has over 10 years experience in the creation, research and development of cell therapy, gene therapy, regenerative medicine ... 2.4 Development of genome modification technologies: gene-based cell therapies. 2.5 Committed cell types: ideal candidates for ... of non-integrative gene therapy products and has published and presented broadly within the field of regenerative medicine/ ...
Abeona Receives FDA Regenerative Medicine Advanced Therapy Designation for Gene Therapy in Epidermolysis Bullosa - THE BIO...
... announced that the FDA has granted Regenerative Medicine Advanced Therapy designation to EB-101, a gene-corrected autologous ... ex-vivo gene-corrected cell therapy in which the COL7A1 gene is inserted into a patient`s own skin cells (keratinocytes) for… ... cell therapy product for patients with recessive dystrophic epidermolysis bullosa (RDEB). Abeona`s EB-101 product is an ... Similar to Breakthrough Therapy designation, the RMAT allows companies developing regenerative medicine therapies to work more ...
ComplianceOnline Announces Seminar on FDA Regulation of Regenerative Medicine
2-Day In-Person Seminar On FDAs Regulation of Regenerative Medicine including Stem Cell Treatments, Tissue Engineering and ... FDAs Regulation of Regenerative Medicine including Stem Cell Treatments, Tissue Engineering and Gene Therapies ... His biologic experience includes viral antigens, enzymes, monoclonal antibodies, gene therapy products and therapeutic proteins ... Course "FDAs Regulation of Regenerative Medicine including Stem Cell Treatments, Tissue Engineering and Gene Therapies" has ...
News Articles | RAPS
Drug Reform, Expedited Pathways, Regenerative Medicine and Gene Therapy *05 June 2018 ... regulatory and economic challenges for gene therapies, re-designing regulatory capabilities to improve operational efficiency ... Expanded Access Policy Requirements, Orphan Drug Legislation and Gene Therapy Regulatory Challenges *01 May 2018 ... Articles posted throughout May included global opportunities and requirements for expedited pathways, a harmonized gene therapy ...
Caladrius Biosciences, Inc. (CLBS) Stock Price, Quote, History & News
Caladrius Biosciences to Present at the Alliance for Regenerative Medicine 7th Annual Cell & Gene Therapy Investor Day. BASKING ... "Cognate"), a leading contract development and manufacturing organization in the global cellular therapies industry, announced ... Caladrius Biosciences Receives Advanced Therapy Medicinal Product Classification for CLBS12, its CD34+ Cell Therapy for ... Advanced therapy medicinal products are defined as medical treatments that are based on genes or cells and are intended as long ...
Most Popular Articles : Current Opinion in Ophthalmology
The future of keratoplasty: cell-based therapy, regenerative medicine, bioengineering keratoplasty, gene therapy. Mehta, ... Multiple sclerosis: review of eye movement disorders and update of disease-modifying therapies. Amezcua, Lilyana; Morrow, Mark ... Precision medicine to prevent glaucoma-related blindness. Moroi, Sayoko E.; Reed, David M.; Sanders, David S.; More ... Physical therapy for facial nerve palsy: applications for the physician. van Landingham, Suzanne W.; Diels, Jacqueline; ...
Protecting methods for treatment related to regenerative medicine and gene therapy in Japan. Multi-kinase inhibitors create...
Protecting methods for treatment related to regenerative medicine and gene therapy in Japan. Multi-kinase inhibitors create ... American Society of Clinical Oncology (ASCO) meeting were from phase 3 trials of two targeted therapies with multiple ... Protecting methods for treatment related to regenerative medicine and gene therapy in Japan. Article Abstract:. On August 7, ... Gene therapy: Cursed or inching towards credibility. Article Abstract:. The failures in gene therapy are quite devastating as ...
Cell & Gene Therapy : Pharmaceuticals : UK
Regenerative and Experimental Medicine. • Cell / Molecular Biology. • Cell / Gene Therapy. • Rare & ultra-rare diseases. • ... Adeno-associated virus (AAV) vector-based gene therapy became a principal actor in the development of therapies for monogenic ... Ronzitti then moved to the development of gene therapy approaches for glycogen storage diseases. An innovative gene therapy ... Ronzitti then moved to the development of gene therapy approaches for glycogen storage diseases. An innovative gene therapy ...
Cell & Gene Therapy : Pharmaceuticals : UK
Regenerative and Experimental Medicine. • Cell / Molecular Biology. • Cell / Gene Therapy. • Rare & ultra-rare diseases. • ... The latest developments in cell and gene therapies and specifically in gene editing technologies present unlimited research ... Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network ... Gene therapy manufacturing. Ryan McCoy, Lead Technical Scientist, The Cell and Gene Therapy Catapult. • The value of risk and ...
Minaris Regenerative Medicine to Significantly Expand Manufacturing Capacity for Cell and Gene Therapies in Germany and Japan
... a leading global contract development and manufacturing organization for cell and gene therapies, wholly owned by Showa Denko ... Keywords: Investments; Regenerative Medicine; Genetic Therapy; Induced Pluripotent Stem Cells; Mesenchymal Stem Cells; ... Minaris Regenerative Medicine to Significantly Expand Manufacturing Capacity for Cell and Gene Therapies in Germany and Japan ... About Minaris Regenerative Medicine. Minaris Regenerative Medicine is a global contract development and manufacturing ...
Community Academic Profiles - Faculty & Researchers - Stanford Medicine
Stanford Medicine integrates a premier medical school with world-class hospitals to advance human health. ... Stanford Medicine integrates a premier medical school with world-class hospitals to advance human health. ... Current Research and Scholarly Interests Organ transplantation, regenerative medicine, tissue engineering, gene therapy ... creative teaching protocols and effective clinical therapies. ... From the Special Forces to medicine. Stanford Medicine PA ...
Frontiers | Recent Progress in European Advanced Therapy Medicinal Products and Beyond | Bioengineering and Biotechnology
This report presents a succinct analysis of developments in the regenerative medicine landscape, including immuno-oncology, ... This report presents a succinct analysis of developments in the regenerative medicine landscape, including immuno-oncology, ... Regenerative Medicine International Society European Chapter 2017 Industry Symposium. ... technology adoption and permeation of innovative advanced therapy medicinal products in the clinical set up are reflected upon ...
Request Bundle Reports - Regenerative Medicine Market - Global Forecast to 2025 | MarketsandMarkets
Regenerative Medicine Market by Product (Cell Therapies (Autologous, Allogenic), Stemcell Therapy, Tissue-engineering, Gene ... What are the Known and Unknown Adjacencies Impacting the Regenerative Medicine Market ... Therapy), Application (Wound Care, Musculoskeletal, Oncology, Dental, Ocular), Geography - Global Forecast to 2025 ...
Evox Therapeutics Appoints Martin Andrews as Non-Executive Director
Here, he led the global rare disease business and oversaw the development of a portfolio of ex vivo gene therapies, and the ... Martin has previously held Board positions at Orchard Therapeutics and the Alliance for Regenerative Medicine. He is currently ... Furthermore, under his leadership, GlaxoSmithKline transferred its gene therapy portfolio to Orchard Therapeutics. Prior to ... gene therapy and vaccines.. Martin is an experienced Non-Executive Director and commercial leader, with a strong track record ...
AlloVir Announces Viralym-M Granted Regenerative Medicine Advanced Therapy (RMAT) Designation for the Treatment of Hemorrhagic...
College of Medicines Center for Cell and Gene Therapy, is the leader in the development of novel cell therapies with a focus ... AlloVir Announces Viralym-M Granted Regenerative Medicine Advanced Therapy (RMAT) Designation for the Treatment of Hemorrhagic ... announced that it has received Regenerative Medicine Advanced Therapy (RMAT) designation from the U.S. Food and Drug ... ElevateBio BaseCamp, a company-owned Cell and Gene Therapy Center of Innovation, will serve as the R&D, process development and ...
Community Academic Profiles - Faculty & Researchers - Stanford Medicine
... stem cells and gene therapy and will open new pathways into the emerging field of Interventional Regenerative Medicine. ... Looking forward, our ability to super-selectively deliver new therapies directly to target organs. These therapies include ... School of Medicine. Showing 11-20 of 23 Results. * Avnesh Thakor. Assistant Professor of Radiology (Pediatric Radiology) at the ... MicroRNAs are small, non-coding RNAs that regulate the expression of ?suites? of genes. The work in my lab seeks to identify ...
Are Stem Cells Ready for Prime Time? A Look at FDA Research Advances in Regenerative Medicine | FDA
Chief, Cellular and Tissue Therapy. Division of Cellular and Gene Therapies. FDAs Center for Biologics Evaluation and Research ... Bauer joined FDAs Center for Biologics Evaluation and Research in its Division of Cellular and Gene Therapies. ... Are Stem Cells Ready for Prime Time? A Look at FDA Research Advances in Regenerative Medicine ... Are Stem Cells Ready for Prime Time? A Look at FDA Research Advances in Regenerative Medicine ...
The 2019 Rare Neurological Disease Special Report Is Now Available - NORD (National Organization for Rare Disorders)
... are the profile of the New York Genome Center and the Alliance for Regenerative Medicines article on cell and gene therapy. ... and gene-based therapies. Information and resources on gene therapy are a particular focus; of note ... Neurology Reviews and NORD partner to keep the busy clinician abreast of the latest diagnostic tools and medical therapies ...
Guide for Authors
Clinical applications include the therapies of medical technology and regenerative medicine in all clinical disciplines, and ... The journal is relevant to areas such as cancer diagnosis and therapy, implantable devices, drug delivery systems, gene vectors ... These sciences include polymer synthesis and characterization, drug and gene vector design, the biology of the host response, ...
Gene Therapy Conferences 2017
Next-Generation Biologics Market Size | Industry Report, 2018-2028
9.2 The Regenerative Medicine Submarket: Revenue Projections 2017-2028. 9.2.1 Stem Cell and Gene Therapy Launches to Drive ... 9.5.4 There are More Than Five Gene Therapies in Late-Stage Development. 18.104.22.168 ProstAtak: Gene Therapy for Prostate Cancer. ... 9.5 The Gene Therapies Submarket 2017-2028. 9.5.1 Glybera Approved and Set for Launch in the EU. 9.5.2 Gene Therapies Submarket ... Table 9.11 Gene Therapies Submarket: Drivers and Restraints, 2017-2028. Table 9.12 Gene Therapies in Phase II and III Clinical ...
RegenerativeMedicine.net - Article Archives
... of regenerative medicine research and therapies as reviewed by the experts at the McGowan Institute for Regenerative Medicine ... Cooling May Save Trauma Victims Regenerative Medicine Paper Makes Top 10 of Gene Therapy Downloads Regenerative Medicine ... Medicine Therapy Human Blood Cell Found Through Regenerative Medicine Work at Stanford Regenerative Medicine Therapy Used for ... Stem Cell Sorter Regenerative Medicine Therapy for Heart Patients Regenerative Medicine: Rebuilding Our Bodies Regenerative ...
Gene Therapy Market Global Industry Analysis and Growth By 2020 - Size, Share, Trends, Opportunities, Top 5 Key Players and...
The mutation of genes can lead to a genetic disorder in which proteins are made incorrectly. So for that, gene therapy is used ... Genes are genetic materials composed of deoxyribonucleic acid (DNA), responsible for producing proteins that have a key role in ... For instance, According to a published article in 2014 Regenerative Medicine reports 4749 registries of clinical trials related ... These companies are conducting various clinical and pre-clinical developmental stages of gene therapies. Key players are ...
Community Academic Profiles - Faculty & Researchers - Stanford Medicine
Stanford Medicine integrates a premier medical school with world-class hospitals to advance human health. ... Stanford Medicine integrates a premier medical school with world-class hospitals to advance human health. ... with a focus on gene therapy and regenerative medicine. We have created novel methods for inserting therapeutic genes into the ... Current Research and Scholarly Interests My lab is developing innovative gene and stem cell therapies for genetic diseases, ...
Gene Therapy Net Newsletter
... clinical trial databases and more gene therapy information ... Information resource for gene therapy news, clinical trials, ... 15 - 17 May 2019, World Advanced Therapies & Regenerative Medicine Congress 2019, London, UK. ... Conference: 3rd Annual Gene Therapy for Rare Disorders Summit. The Gene Therapy for Rare Disorders focuses exclusively on ... Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network ...
University of Manitoba - Information Services and Technology - Regenerative Medicine Program
Gene Therapy of Neurological Disorders with an emphasize on Rett Syndrome, HOX/HOX-Targets in Neural Stem Cell (NSC)/Brain ... Application of cancer stem cells concept to the development of preventative breast cancer therapies. Origin of breast cancer ... Regenerative Medicine Program. Regenerative medicine is an emerging field of medicine focused on repairing and replacing ... Translational and applied study of cellular therapy products for use in regenerative medicine applications.. Tel: (204) 787- ...
Gene Therapy Net Newsletter
... clinical trial databases and more gene therapy information ... Information resource for gene therapy news, clinical trials, ... World Advanced Therapies and Regenerative Medicine Congress 2017, London, UK. -. 24 - 26 May 2017, 10th Australasian Gene ... Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network ... gene therapy jobs, regulations and guidelines. Other information websites created and maintained by the owner of Gene Therapy ...
Pfizer Raises Gene Therapy Stake with $500M Sanford, NC, Expansion
Pfizer will expand its manufacturing of gene therapies in North Carolina, where the pharma giant joined Gov. Roy Cooper in ... a gene therapy candidate indicated for severe hemophilia A that recently received the FDAs regenerative medicine advanced ... Pfizer will expand its manufacturing of gene therapies in North Carolina, where the pharma giant joined Gov. Roy Cooper in ... Home Genome Editing Gene Therapy Pfizer Raises Gene Therapy Stake with $500M Sanford, NC, Expansion ...
How Gene Therapy can Help You Stop Aging, Build Muscles, and Fight Diseases
What is Gene Therapy and how Practical is it? 2. How Gene Therapies or Gene Editing help you Stop Aging, Build Muscle and Fight ... As a strong proponent of progress and education for the advancement of regenerative medicine modalities, she serves as a ... 1. What is Gene Therapy and how Practical is it?. 2. How Gene Therapies or Gene Editing help you Stop Aging, Build Muscle and ... How Gene Therapy can Help You Stop Aging, Build Muscles, and Fight Diseases Posted by John Davies in categories: bioengineering ...
RNA Therapeutics : Pharmaceuticals : UK
... her PhD at the Centre for Regenerative Medicine at the University of Modena in 2008 working on development of gene therapy for ... the company is now also focusing on the development of AAV-based gene therapies for several neuromuscular diseases. ... Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network ... Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network ...
Global Cell Therapy Technologies market set to grow to $23bn by 2024
The Cell therapy technology is one of the fastest growing markets set to grow to $23bn by 2024. According to Visiongain ... "Cell therapy technologies are used across various research areas including gene therapy, cancer vaccines, regenerative medicine ... availability of advanced cell therapy technologies and growing demand of cell therapies are expected to further propel the ... It represents the umbrella of recent advancement in the field of gene therapy, drug delivery, cancer vaccines, various ...
Seven Biopharma Trends to Watch in 2021
Check out gene editing, gene and cell therapy, and other areas. ... According to the Alliance for Regenerative Medicine, gene ... Most of these therapies are focused on cancer, but one therapy in preclinical development is targeting COVID-19. ... Cell therapy financing grew at an impressive rate. According to the Alliance for Regenerative Medicine, cell therapy financing ... 2. Gene therapy: Big pharma, big deals. Big pharma firms have truly warmed to gene therapy to expand their pipelines in 2021 ...
Cognate BioServices & Its Gene Therapy Division Cobra Biologics Announce Major Expansion
... the gene therapy division of the Cognate BioServices group, recently announced a multi-phase augmentation of its plasmid DNA ... organization focused on providing the broadest range of commercialization services to regenerative medicine, cellular ... This is critically important to our clients around the world who are commercializing cell and gene therapies that require rapid ... Cognate BioServices & Its Gene Therapy Division Cobra Biologics Announce Major Expansion. Cobra Biologics, the gene therapy ...
The Virtue of Miami in January - World Stem Cell Summit
HCP Busted for Selling Fake Stem Cell Therapy * New institute to leverage experts to advance regenerative medicine ... co-located with Phacilitiates Cell and Gene Therapy World and Immuno-Oncology Frontiers World events. ... Mid-term clinical trial results show similar outcomes in two promising cell therapies for CLI ... There are many regenerative medicine conferences to consider in 2018, but I urge you to jump-start your success by attending ...
SELECTBIO - Stem Cells in Drug Discovery Speaker Biography
... regenerative medicine, gene therapy, and macromolecules/biologic products. Client relationships have ranged from large pharma ... Regenerative Medicine has been an area of strong focus with over 30 engagements, several published papers, and numerous invited ... cell and gene therapy programs in Pfizer R&D. Prior to this Devyn was Head of Strategy for the Pharmatherapeutics Division of ...
CPhI Festival of Pharma | Speakers
Hes specialty area is bio pharmaceuticals, biosimilar, chemical pharmaceuticals, IVD, cell therapy, gene therapy and genetic ... Member of Alliance for Regenerative Medicine (ARM) Board of Directors. Previously CEO of Zelluna Immunotherapy from 2017 to end ... such as those required to cryopreserve and administer cell and gene therapies. To achieve this, Alex leads a dynamic ... At his time at PCT as their COO he supported over 20 clinical trials in the Cell and Gene Therapy field. These trials ranged ...
CCRM: Cultivating Good Health one Stem Cell Treatment at a Time • Ontario Society of Professional Engineers
... profit organization supporting the development of technologies that accelerate the commercialization of cell and gene therapies ... Regenerative medicine harnesses the power of stem cells, genes, biomaterials and molecules to repair, regenerate or replace ... In 2016, CCRM partnered with GE Healthcare to strategically identify gaps in the manufacturing of cell and gene therapies. As ... The Centre welcomes pharma, biotech and cell therapy partners to bring this initiative to life. ...
Life Sciences & Healthcare | Taylor Wessing Hub | Gradcracker Home | Gradcracker - Careers for STEM Students
For example, we focus on emerging technological fields of advanced therapies such as cell and gene therapy; tissue engineering ... and regenerative medicine; areas of convergence such as the increasing importance of the collection and protection of patient ... We also advise on emerging client service and business models relating to personalised medicine and patient experience-driven ...
CellGenix Completed First Step of Facility Expansion to Stay on Top of the Increasing Demands for GMP Cell Culture Reagents
... gene therapy and regenerative medicine space. The expansion of our facility is a result of the robust, sustainable and ... we strengthen our position as a leading partner for all companies active in the manufacturing of cell and gene therapies. It ... gene therapy and regenerative medicine. The superior quality GMP reagents are used by leading experts and are proven in ... a global manufacturing leader of GMP-grade raw materials for cell therapy, gene therapy and tissue-engineered products, ...
Stem cellsCenter for Regenerative MedicineInstitute for Regenerative MedicineTherapeuticsField of regenerative medicineMolecular Biology20192018Tissue engineering and geApproachesRegenerateGENOMICSMarket is segmentedImmunotherapyOrganAdvanced therapy medicinal productsTissuesMedicine'sResearchersAdvances2016CellularTreatmentsPreclinicalDegenerative diseasesTherapeuticDevelopmentAllianceRegenerationDEVELOPMENTS2020DiseasesProductsCell and Gene TherapyRecessive dystrophic epidermIntrinsicBiomaterialClinicBiologyPotentialMechanisms
- Can gene therapy plus liver "stem cells" cure diabetes? (nature.com)
- Here's a trio of three early stage studies that look encouraging for using stem cells as therapies in the brain. (nature.com)
- People who need a recent, accessible summary of what stem cells could do in medicine should check out this Newsweek piece, Will Stem Cells Finally Deliver? (nature.com)
- The Niche is a blog hosted by Nature Reports Stem Cells to provide an informal forum for debate and commentary on stem cell research and its wider implications for ethics, policy, business, and medicine. (nature.com)
- The announcement was made by Minister Moridi to the 150 scientists working on stem cells and regenerative medicine at the Institute. (insights.bio)
- This training workshop will provide a historical context for the use of stem cells in medicine, where the field has been and where it is going. (prweb.com)
- This two-day workshop will host discussions on fundamentals of stem cells and on how the FDA regulates regenerative treatments and therapies. (prweb.com)
- In addition, the course will provide the various examples of FDA approved use of stem cells in medicine and what is needed for the field to progress. (prweb.com)
- Now, researchers at the Stanford University School of Medicine in California have developed a novel nanoparticle-based system that allows stem cells to be tracked in real time in a living mouse for up to a year after injection. (nature.com)
- Delivering stem cells to specific tissues is a very big challenge, since basically all investigators have to shoot blindly," says Sanjiv Gambhir , director of Stanford's molecular imaging program who led the work published online today in Science Translational Medicine . (nature.com)
- Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in the clinic for approximately 10 years. (nature.com)
- Cell therapy based on stem cells describes the process of introducing stem cells into tissue to treat a disease with or without the addition of gene therapy. (nature.com)
- Hematopoietic stem cells (HSCs) have been widely used for allogeneic cell therapy. (nature.com)
- Number of registered clinical trials of mesenchymal stem cells-based therapy on ClinicalTrials.gov. (nature.com)
- Clinical phages of mesenchymal stem cells-based therapy. (nature.com)
- Harris DT, Badowski M, Ahmad N, Gaballa M. The potential of cord blood stem cells for use in regenerative medicine. (springer.com)
- Phacilitate World Leaders Forum, incorporating Cell & Gene Therapy World, Immuno-Oncology Frontiers World, and our shared Cord Blood & Perinatal Stem Cells track. (worldstemcellsummit.com)
- Endometrial regenerative cells (ERCs) is an attractive novel type of adult mesenchymal stem cells that can be non-invasively obtained from menstrual blood and are easily replicated at a large scale without tumorigenesis. (biomedcentral.com)
- On a commercial scale, many scientists are utilizing regenerative medicine approaches to rebuild stem cells and tissues and in some clinical trials, practicing novel therapies is a gateway to modern way of treating degenerative diseases. (medindia.net)
- His group is also investigating the function of progenitor cells during repair, and the translational use of fat-derived stem cells in chronic wound therapy and tissue engineering. (stanford.edu)
- Researchers are engaged in developing technologies based on biologics, genes, somatic as well as stem cells. (bio-medicine.org)
- ST-400 is an autologous cell therapy that involves gene editing of a patient's own hematopoietic stem cells (HSCs) using zinc finger nuclease (ZFN) technology. (pharmiweb.com)
Center for Regenerative Medicine2
- 34 studies in Center for Regenerative Medicine (all studies, either open or closed). (mayo.edu)
- Co-organizers of the World Stem Cell Summit are the Regenerative Medicine Foundation, Karolinska Institute, Maryland Stem Cell Research Fund/TEDCO, Mayo Clinic, The New York Stem Cell Foundation, Nova Southeastern University and NSU Cell Therapy Institute, The Cure Alliance, Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine, University of Florida Center for Regenerative Medicine, Wake Forest Institute for Regenerative Medicine and Weill Cornell Medicine. (worldstemcellsummit.com)
Institute for Regenerative Medicine7
- The McGowan Institute for Regenerative Medicine was selected as one of the winners of this inaugural award for its pioneering development and clinical implementation of regenerative medicine-based therapies. (pitt.edu)
- Since the formation of the McGowan Center for Artificial Organ Development (1992) and the McGowan Institute for Regenerative Medicine (2001) there have been many accomplishments advancing the science and clinical achievements in regenerative medicine-based therapies. (pitt.edu)
- McGowan Institute for Regenerative Medicine affiliated faculty member Julie Phillippi, PhD , Assistant Professor in the Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, received NIH funding for her project entitled "Matrix mediated vasa vasorum dysfunction in thoracic aortic disease. (pitt.edu)
- The funds are being directed to the Institute for Regenerative Medicine (Toronto, Canada) to support investigations into potential new treatments and therapies for people living with chronic diseases, such as cancer, multiple sclerosis and diabetes - diseases that contribute over a hundred billion dollars to healthcare costs annually. (insights.bio)
- We are extremely pleased with this government's support and investment in the Ontario Institute of Regenerative Medicine, which we will turn into stem cell therapies, technologies and innovation for Ontario's future health and prosperity," said Janet Rossant, Executive Director of the Ontario Institute for Regenerative Medicine. (insights.bio)
- The 2019 WSCS was led by the Regenerative Medicine Foundation and principal organizing partners, Maryland Stem Cell Research Fund, The Cure Alliance, Interdisciplinary Stem Cell Institute at the University of Miami, Wake Forest Institute for Regenerative Medicine, Weill Cornell Medicine and media partner Leapsmag . (globenewswire.com)
- RICHMOND, Calif., April 27, 2018 /PRNewswire/ -- Sangamo Therapeutics, Inc. (NASDAQ: SGMO) announced today that the California Institute for Regenerative Medicine (CIRM) has awarded an $8 million grant for Sangamo to evaluate ST-400, a gene-edited cell therapy candidate for people with transfusion-dependent beta-thalassemia. (pharmiweb.com)
- Gene therapy developer, Abeona Therapeutics , announced that the FDA has granted Regenerative Medicine Advanced Therapy designation to EB-101, a gene-corrected autologous cell therapy product for patients with recessive dystrophic epidermolysis bullosa (RDEB). (thebioconnection.com)
- Caladrius Biosciences, Inc. (CLBS) ("Caladrius" or the "Company"), a late-stage therapeutics development biopharmaceutical company pioneering advancements of cell therapies in select cardiovascular and autoimmune diseases, and Cognate BioServices, Inc. ("Cognate"), a leading contract development and manufacturing organization in the global cellular therapies industry, announced today that they have entered into a manufacturing agreement for the production of CLBS14, Caladrius' CD34+ cell therapy. (yahoo.com)
- Caladrius Biosciences, Inc. (CLBS) ("Caladrius" or the "Company"), a late-stage therapeutics development biopharmaceutical company pioneering advancements of cell therapies in select cardiovascular and autoimmune diseases, announces that the Company will release financial results for the six months ended June 30, 2019 after close of the U.S. financial markets on Thursday, August 8, 2019. (yahoo.com)
- Cell and gene therapeutics have revolutionised modern medicine and mark a new generation in biomedical and agricultural sciences. (smi-online.co.uk)
- Dr. Kathy High, an accomplished hematologist with a longstanding interest in gene therapy for genetic disease, began her career studying the molecular basis of blood coagulation and the development of novel therapeutics for the treatment of bleeding disorders. (terrapinn.com)
- The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies. (wiley.com)
- Brainstorm Cell Therapeutics to Present at ARM's 5th Annual Cell & Gene Therapy Investor Day, April 27. (bio-medicine.org)
- About BrainStorm Cell Therapeutics Inc.BrainStorm Cell Therapeutics Inc. is a biotechnology company engaged in the development of first-of-its-kind adult stem cell therapies derived from autologous bone marrow cells for the treatment of neurodegenerative diseases. (bio-medicine.org)
- MUNICH, Germany, January 13, 2020 / B3C newswire / -- apceth Biopharma GmbH , a subsidiary of Hitachi Chemical Co., Ltd. and a leading company for the manufacturing of cell and gene therapeutics, starts the commercial manufacturing of Zynteglo™ ▼ , a product of bluebird bio, Inc. Today bluebird bio announced the market entry of its gene therapy Zynteglo in Germany, the first country globally where Zynteglo is commercially available. (b3cnewswire.com)
- About apceth Biopharma GmbH apceth Biopharma, a subsidiary of Hitachi Chemical Co., Ltd., is a pioneering company in regenerative medicines and a leading and certified Contract Development and Manufacturing Organization for cell and gene therapeutics with a broad international customer base. (b3cnewswire.com)
- Sangamo Therapeutics, Inc. is focused on translating ground-breaking science into genomic therapies that transform patients' lives using the company's industry leading platform technologies in genome editing, gene therapy, gene regulation and cell therapy. (pharmiweb.com)
Field of regenerative medicine2
- Ontario is exceptionally rich in terms of research talent, commercial capacity and a strong health care system, which is why it is a powerhouse in the field of regenerative medicine. (insights.bio)
- Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. (elsevier.com)
- The Hamon Center for Regenerative Science and Medicine is pleased to announce the 2019-2020 CRSM Regenerative Medicine Seminar Series. (utsouthwestern.edu)
- The Hamon Center for Regenerative Science and Medicine is currently accepting nominations by faculty members for 2019-2020 CRSM Trainee Fellowships. (utsouthwestern.edu)
- Miami, FL, Jan. 25, 2019 (GLOBE NEWSWIRE) -- The international regenerative medicine community concluded a week of sharing breakthroughs, facing challenges and developing collaborations at the 2019 co-located Phacilitate Leaders World and World Stem Cell Summit (WSCS) at the Hyatt Regency Miami, January 22-25, 2019. (globenewswire.com)
- The 2019 Stem Cell and Regenerative Medicine Action Award honorees were recognized at a gala reception and dinner on Wednesday, January 23rd at the Hyatt Regency Miami. (globenewswire.com)
Tissue engineering and ge3
- ComplianceOnline, the leading GRC advisory network, and ex-FDA official Debra Webster and regulatory consultant David A. Cummings will conduct a two day seminar on FDA's regulation of regenerative medicine including stem cell treatments, tissue engineering and gene therapies. (prweb.com)
- Course "FDA's Regulation of Regenerative Medicine including Stem Cell Treatments, Tissue Engineering and Gene Therapies" has been pre-approved by RAPS as eligible for up to 12 credits towards a participant's RAC recertification upon full completion. (prweb.com)
- ComplianceOnline, the leading governance, risk and compliance advisory network with over 500 experts in various regulatory subjects, today announced a seminar on FDA's Regulation of Regenerative Medicine including Stem Cell Treatments, Tissue Engineering and Gene Therapies. (prweb.com)
- Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. (schweitzer-online.de)
- Studying integrative medicine approaches to painful spinal stenosis. (mayoclinic.org)
- In this review, we present and review the current status of two different approaches to restoring or protecting hearing, gene therapy, including the newly introduced CRISPR/Cas9 genome editing, and stem cell therapy, and suggest the future direction. (hindawi.com)
- Gene therapy not only helps injured brain cells to live longer and regenerate, but also changes the shape of the cells, according to researchers at The University of Western Australia (UWA). (regenerativemedicine.net)
- The Ortved Laboratory at New Bolton Center is focused on understanding the pathophysiology of post-traumatic osteoarthritis (PTOA) and developing gene and cell-based therapies to help regenerate cartilage and prevent the development of PTOA following joint injury. (upenn.edu)
- Our lab is focused on understanding the pathogenesis of PTOA and developing regenerative medicine therapies to help regenerate cartilage and prevent the development of PTOA following joint injury. (upenn.edu)
- Regenerative medicines have the unique ability to repair, replace and regenerate tissues and organs, affected due to some injury, disease or due to natural aging process. (bio-medicine.org)
- In contrary, regenerative medicines have the capability to replace or regenerate the tissues and organs suffering from injury or disease. (bio-medicine.org)
Market is segmented3
- Regenerative medicine market is segmented into cell-based products and acellular products, based on type. (medindia.net)
- Regenerative medicine market is segmented into cell therapy, gene therapy, tissue engineering and immunotherapy, based on therapy. (medindia.net)
- On the basis of technology used, this market is segmented into small molecules & biologics, gene therapy and cell therapy. (bio-medicine.org)
- Researchers at Mayo Clinic are studying regenerative medicine techniques for restoring tissue and organ function. (mayo.edu)
- Operative Technique of Donor Organ Procurement for En Bloc Heart-Liver Transplantation. (stanford.edu)
- The good news is the eye is an ideal organ for gene therapy as it is well protected from the body's immune response. (retina-international.org)
- To design biomedical therapies for organ repair, it is necessary to develop a detailed understanding of natural regeneration. (jneurosci.org)
- Regenerative medicine also helps in understanding and promoting the ability of an organ or tissue to repair by self. (medindia.net)
- According to the World Health Organization, there are approximately 100,000 known beta-thalassemia patients worldwide, with ~19,000 of those in the United States and Europe.1 The majority of these patients are transfusion-dependent, and their current standard of care includes a chronic regimen of red blood cell transfusions, which may lead to iron overload and organ damage even with daily iron chelation therapy. (pharmiweb.com)
Advanced therapy medicinal products2
- Advanced therapy medicinal products are defined as medical treatments that are based on genes or cells and are intended as long-term or permanent therapeutic solutions to acute or chronic human diseases at a genetic, cellular or tissue level. (yahoo.com)
- apceth owns state-of-the-art manufacturing facilities with Grade B/A, C and D cleanrooms (ISO 5, ISO 7, ISO 8, BSL2) and is certified according to regulatory requirements for cell and gene therapies (Advanced Therapy Medicinal Products, ATMPs). (b3cnewswire.com)
- Thus Regenerative Medicine promises the repair of body parts with their own living tissues by inculcating Scaffolds. (eventbrite.com)
- Biologic Tissues consist of the cells,the extracellular matrix (made up of a complex of cell secretions immobilized in spaces continuous with cells), and the signaling systems, which are brought into play through differential activation of Genes or cascades of genes whose secreted or transcriptional products are responsible for cueing tissue building and differentiation. (eventbrite.com)
- These medicines are capable of restoring the functionality of cells and tissues. (bio-medicine.org)
- Reversing autoimmune type 1 diabetes without immunosuppression has proven to be extremely difficult, but in a study published in Cell Stem Cell , researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine report achieving that outcome in mice using gene therapy. (pitt.edu)
- Researchers all over the world are investigating retinal dystrophies, also referred to as retinal degenerations, and are continuously identifying the causative genes and symptoms with the intention of developing treatments and, ultimately, cures. (retina-international.org)
- The researchers used a specially engineered virus to deliver extra copies of the gene for NGF into the hearts of mice. (regenerativemedicine.net)
- Research in the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program is led by Atta Behfar, M.D., Ph.D., and Andre Terzic, M.D., Ph.D., supported by a dedicated administrative staff, and carried out by expert researchers and M.D.-Ph.D. students. (mayo.edu)
- Ms. Rowe has expertise in processing tissue samples from research studies, allowing researchers in the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program to evaluate heart muscle tissue for signs of regeneration. (mayo.edu)
- The Alliance for Regenerative Medicine (ARM) is an international multi-stakeholder advocacy organization that promotes legislative, regulatory and reimbursement initiatives necessary to facilitate access to life-giving advances in regenerative medicine worldwide. (marketwired.com)
- In this review, recent advances in the application of gene therapies to treat inherited muscle disorders are presented, including Duchenne muscular dystrophy and x-linked myotubular myopathy. (nih.gov)
- However, in order for significant advances in regenerative biomedicine to occur, it is necessary to identify new pathways that can be targeted by therapies to induce appendage regeneration after injury and nonpermissive wound healing. (jneurosci.org)
- We're hopeful that advances in regenerative medicine over the next decade might mean we can finally reverse the damage caused by a heart attack. (regenerativemedicine.net)
- Cell Gene Therapy Insights 2016;2(2), 141-145. (insights.bio)
- Andrew Obenshain is Head of Europe at bluebird bio, a biotech company focused on developing potentially transformative cell & gene therapies for severe genetic and rare diseases.Before taking up this role in 2016, he was at Shire in Paris, France where he was the general manager of France and. (terrapinn.com)
- New vectors are now becoming available as gene therapy delivery tools, and recent preclinical experiments have demonstrated the feasibility, safety, and efficacy of gene therapy with adeno-associated virus for long-term correction of muscle pathology and weakness in myotubularin-deficient canine and murine disease models. (nih.gov)
- Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. (wiley.com)
- His biologic experience includes viral antigens, enzymes, monoclonal antibodies, gene therapy products and therapeutic proteins. (prweb.com)
- Potential areas for therapeutic synergies between rehabilitation medicine and genetics are also discussed. (nih.gov)
- The event includes clinical and commercial experts who are on-hand to address specific questions regarding the outlook for these products, as well as offer insight into how cell and gene therapies could impact the standard of care in key therapeutic areas such as cardiovascular disease, wound healing and tissue repair, ophthalmology, neurodegenerative diseases, diabetes and oncology. (bio-medicine.org)
- Dr. Meenakshi Siddharthan is identifying new therapeutic targets at the gene and protein levels using samples from patients. (mayo.edu)
- Scientists have been studying this process to better understand human development, birth defects, and cancer and to advance technologies like organoid generation and cell replacement therapy. (pitt.edu)
- He has broad experience in the cell therapy area with over 30 years working in various senior management roles in research and development, manufacturing and quality in cell and gene therapy. (terrapinn.com)
- Initially members of RI were focused on gene therapies solely, but the development of innovative technologies and a better understanding of biology has meant that there are now many more pillars of research offering hope for treatment. (retina-international.org)
- The key driving factors responsible for the growth of regenerative medicine market includes government and private subsidy to assist development of regenerative medicine. (medindia.net)
- Specifically, we are interested in gene and cell therapies targeted at reducing post-traumatic inflammation and improving repair of the articular surface, thereby preventing the development of PTOA in the first place. (upenn.edu)
- The Hitachi Chemical's Regenerative Medicine Business Sector provides contract development and manufacturing organization (CDMO) services at current Good Manufacturing Practices (cGMP) standards, including clinical manufacturing, commercial manufacturing, and manufacturing development. (b3cnewswire.com)
- We believe the precision, efficiency and specificity of zinc finger nuclease gene editing has the potential to differentiate ST-400 from other genomic therapies in development for this disease. (pharmiweb.com)
- Organized by the Alliance for Regenerative Medicine (ARM) and co-hosted with Piper Jaffray , this one-day, high impact program provides institutional, strategic and venture investors with unique insight into the financing hypothesis for advanced therapies-based treatment and tools. (bio-medicine.org)
- A local, early increase in intracellular sodium is required for initiating regeneration following Xenopus laevis tail amputation, and molecular and pharmacological inhibition of sodium transport causes regenerative failure. (jneurosci.org)
- Our previous work has shown that when growth-promoting genes are introduced into injured brain cells for long periods of time (up to 9 months), the cells' capacity for survival and regeneration is significantly increased," he said. (regenerativemedicine.net)
- Mr. Rolland is a student in the Graduate Research Employment Program who is focused on cell-free gene delivery technologies for cardiovascular regeneration. (mayo.edu)
- New Bolton Center's Surgery faculty are actively engaged in groundbreaking research, including stem cell therapy, bone growth and regeneration, and stimulating the synthesis of cartilage components in the treatment of equine arthritis. (upenn.edu)
- We are looking forward to "Advance Therapies Week in 2020 in Miami" and taking our event to the next impactful level" said Michael Adeniya, Event Director at Phacilitate. (globenewswire.com)
- However, gene therapies are expected to be the fastest emerging technology, growing at a CAGR of 28.6% during 2014-2020. (bio-medicine.org)
- Established under the 21st Century Cures Act, the RMAT designation is an expedited program for the advancement and approval of regenerative medicine products where preliminary clinical evidence indicates the potential to address unmet medical needs for life-threatening diseases or conditions. (ntbinfo.no)
- It is found that various failures of gene therapy have raised concerns on the safety and efficacy of gene therapy but the scientists are quite optimistic about the successful use of gene therapy in curing various diseases. (readabstracts.com)
- These medicines find applicability in wide range of degenerative disorders including dermatology, neurodegenerative diseases, cardiovascular and orthopedic applications. (bio-medicine.org)
- Similar to Breakthrough Therapy designation, the RMAT allows companies developing regenerative medicine therapies to work more closely and frequently with the FDA, and RMAT-designated products may be eligible for priority review and accelerated approval. (ntbinfo.no)
- This article (the first of a two-part series) will cover each of the five pillars as a means of discussing requirements for planning the commercial-scale manufacture of products related to cell therapy and regenerative medicine. (bioprocessintl.com)
- Like all manufacturers seeking to create market-winning products, cell-therapy manufacturers must develop and refine their processes to be robust and error-proof, using manufacturing equipment that produces consistent and repeatable processes. (bioprocessintl.com)
- The TRO builds on an increasingly vibrant translational culture across UCL by collaboration with academics, industry partners and external funding bodies, to facilitate the translation of UCL's emerging research into therapies and medical products. (smi-online.co.uk)
- apceth has successfully obtained manufacturing licenses for multiple cell therapy products for clinical use as well as one commercial cell-based gene therapy. (b3cnewswire.com)
- The small molecules and biologics segment have the largest contribution among all other technologies used for creating regenerative products. (bio-medicine.org)
Cell and Gene Therapy5
- Cell and Gene Therapy will be inviting speakers from global pharmaceutical organisations, leading biotech companies and internationally renowned academic institutions. (smi-online.co.uk)
- Expect over 16 presentations and case studies focused on the key aspects of drug discovery, safety and toxicology assessments, bioprocessing, regulatory frameworks and patient access in the field of cell and gene therapy. (smi-online.co.uk)
- Pamela has advised and supported successful applications for cell and gene therapy projects which she is now managing in both the pre-clinical and early clinical phases. (smi-online.co.uk)
- Attendees of World Stem Cell Summit, Cell and Gene Therapy World and Immuno-Oncology World have access to shared partnering app! (worldstemcellsummit.com)
- To improve cartilage repair using stem cell and gene therapy. (upenn.edu)
Recessive dystrophic epiderm1
- Although MSCs for cell therapy have been shown to be safe and effective, there are still challenges that need to be tackled before their wide application in the clinic. (nature.com)
- Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. (schweitzer-online.de)
- Contributing partners include Mayo Clinic, Sanford Health, New York Stem Cell Foundation and Nova Southeastern University Cell Therapy Institute. (globenewswire.com)
- She supports planning and coordination of the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program and its activities. (mayo.edu)
- Ms. Nagel supports surgical care and investigative models to enhance the mission and vision of the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program. (mayo.edu)
- This book examines recent progress in our understanding of the biology of these cells, how they are regulated, and opportunities for using them in disease therapies. (cshlpress.com)
- The study was led by Winthrop Professor Alan Harvey from UWA's School of Anatomy, Physiology and Human Biology, and Associate Professor Jennifer Rodger, National Health and Medical Research Council (NHMRC) Research Fellow in Experimental and Regenerative Neurosciences at UWA's School of Animal Biology. (regenerativemedicine.net)
- Panel I: Cell Therapy Beyond Oncology: Where Does the Greatest Potential Lie? (marketwired.com)
- Seven speakers from the US and six from Japan will discuss the innovations in three-dimensional (3D) bioprinting of various anatomical structures and their potential use in regenerative medicine. (fda.gov)
- Currently, there are 344 registered clinical trials in different clinical trial phases ( Figure 2 ) aimed at evaluating the potential of MSC-based cell therapy worldwide. (nature.com)
- The en bloc technique offers several potential advantages over the traditional sequential technique. (stanford.edu)
- These therapies may have the potential to be administered to many different forms of IRD, and not just gene specific conditions. (retina-international.org)
- In addition, Dr. Ralph Kern , MD, MHSc, Chief Medical Officer & Chief Operating Officer, will participate in a panel titled "Cell Therapy Beyond Oncology: Where Does The Greatest Potential Lie? (bio-medicine.org)
- In addition, the regenerative potential of fatally damaged vestibular HCs has been demonstrated [ 4 ]. (hindawi.com)
- Gene therapy also has the potential to bolster the weak healing response in articular cartilage. (upenn.edu)
- The key reason for the growth of this technology can be attributed to the tremendous potential of gene therapy in minimizing immune rejections, which commonly occur after transplantations. (bio-medicine.org)
- American Society of Clinical Oncology (ASCO) meeting were from phase 3 trials of two targeted therapies with multiple mechanisms of action or multi-kinase inhibitors. (readabstracts.com)
- In this review, we summarize the recent opinions on methods, timing and cell sources for MSC administration in clinical applications, and provide an overview of mechanisms that are significant in MSC-mediated therapies. (nature.com)