Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.
The evacuation of food from the stomach into the duodenum.
The motor activity of the GASTROINTESTINAL TRACT.
A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.
The normal process of elimination of fecal material from the RECTUM.
Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.
Oil obtained from seeds of Ricinus communis that is used as a cathartic and as a plasticizer.
Properties and processes of the DIGESTIVE SYSTEM as a whole or of any of its parts.
A plant genus of the family RUTACEAE. Some members of Zanthoxylum are reclassified from ELEUTHEROCOCCUS, Melicope, and EVODIA. The twigs are used as dental brushing sticks (TOOTHBRUSHING). Most plants that are called Fagara have been reclassified as Zanthoxylum, however some Fagara were reclassified to MELICOPE (also in the Rutacea family) or to GLEDITSIA (a genus in the FABACEAE family).
Medical practice or discipline that is based on the knowledge, cultures, and beliefs of the people in EAST ASIA.
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.
Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition.
Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.
An agonist of RECEPTORS, ADRENERGIC ALPHA-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of DEXMEDETOMIDINE.
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
A subtype of G-protein-coupled SEROTONIN receptors that preferentially couple to GS STIMULATORY G-PROTEINS resulting in increased intracellular CYCLIC AMP. Several isoforms of the receptor exist due to ALTERNATIVE SPLICING of its mRNA.
A plant genus of the family VERBENACEAE. Members contain lantadene and other TRITERPENES.
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).
Deciduous plant rich in volatile oil (OILS, VOLATILE). It is used as a flavoring agent and has many other uses both internally and topically.
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.
The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
A dopamine D2 antagonist that is used as an antiemetic.
Uptake of substances through the lining of the INTESTINES.
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.
The relationship between the dose of an administered drug and the response of the organism to the drug.
A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
Live microbial DIETARY SUPPLEMENTS which beneficially affect the host animal by improving its intestinal microbial balance. Antibiotics and other related compounds are not included in this definition. In humans, lactobacilli are commonly used as probiotics, either as single species or in mixed culture with other bacteria. Other genera that have been used are bifidobacteria and streptococci. (J. Nutr. 1995;125:1401-12)
The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
Drugs that selectively bind to and activate alpha adrenergic receptors.
The action of a drug that may affect the activity, metabolism, or toxicity of another drug.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
The giving of drugs, chemicals, or other substances by mouth.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Elements of limited time intervals, contributing to particular results or situations.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.

Segmental colonic transit after oral 67Ga-citrate in healthy subjects and those with chronic idiopathic constipation. (1/712)

Measurement of segmental colonic transit is important in the assessment of patients with severe constipation. 111In-diethylenetriamine pentaacetic acid (DTPA) has been established as the tracer of choice for these studies, but it is expensive and not readily available. 67Ga-citrate is an inexpensive tracer and when given orally is not absorbed from the bowel. It was compared with 111In-DTPA in colonic transit studies in nonconstipated control subjects and then in patients with idiopathic constipation. METHODS: Studies were performed after oral administration of 3 MBq (81 microCi) 67Ga-citrate or 4 MBq (108 microCi) 111In-DTPA in solution. Serial abdominal images were performed up to 96 h postinjection, and computer data were generated from geometric mean images of segmental retention of tracer, mean activity profiles and a colonic tracer half-clearance time. RESULTS: There were no differences in segmental retention of either tracer or in mean activity profiles between control subjects and constipated patients. Results in constipated subjects were significantly different from those in controls. The mean half-clearance times of tracer for control subjects were 28.8 h for 67Ga-citrate and 29.9 h for 111In-DTPA in control subjects and 75.0 h for 67Ga-citrate and 70.8 h for 111In-DTPA in constipated patients. CONCLUSION: Oral 67Ga-citrate can be used as a safe alternative to 111In-DTPA for accurate measurement of segmental colonic transit.  (+info)

Antinociceptive properties of the new alkaloid, cis-8, 10-di-N-propyllobelidiol hydrochloride dihydrate isolated from Siphocampylus verticillatus: evidence for the mechanism of action. (2/712)

The antinociceptive action of the alkaloid cis-8, 10-di-n-propyllobelidiol hydrochloride dehydrate (DPHD), isolated from Siphocampylus verticillatus, given i.p., p.o., i.t., or i.c.v., was assessed in chemical and thermal models of nociception in mice, such as acetic acid-induced abdominal constriction, formalin- and capsaicin-induced licking, and hot-plate and tail-flick tests. DPHD given by i.p., p.o., i.t., or i.c.v. elicited significant and dose-related antinociception. At the ID50 level, DPHD was about 2- to 39-fold more potent than aspirin and dipyrone, but it was about 14- to 119-fold less potent than morphine. Its analgesic action was reversed by treatment of animals with p-chlorophenylalanine, naloxone, cyprodime, naltrindole, nor-binaltrorphimine, L-arginine, or pertussis toxin. Its action was also modulated by adrenal-gland hormones but was not affected by gamma-aminobutyric acid type A or type B antagonist, bicuculine, or phaclofen, nor was it affected by glibenclamide. DPHD, given daily for up to 7 days, did not develop tolerance to itself nor did it induce cross-tolerance to morphine. However, animals rendered tolerant to morphine presented cross-tolerance to DPHD. The antinociception of DPHD was not secondary to its anti-inflammatory effect, nor was it associated with nonspecific effects such as muscle relaxation or sedation. DPHD, in contrast to morphine, did not decrease charcoal meal transit in mice, nor did it inhibit electrical field stimulation of the guinea pig ileum or mouse vas deferens in vitro. Thus, DPHD produces dose-dependent and pronounced systemic, spinal, and supraspinal antinociception in mice, including against the neurogenic nociception induced by formalin and capsaicin. Its antinociceptive effect involves multiple mechanisms of action, namely interaction with mu, delta, or kappa opioid systems, L-arginine-nitric oxide and serotonin pathways, activation of Gi protein sensitive to pertussis toxin, and modulation by endogenous glucocorticoids.  (+info)

Prolonged large bowel transit increases serum deoxycholic acid: a risk factor for octreotide induced gallstones. (3/712)

BACKGROUND: Treatment of acromegaly with octreotide increases the proportion of deoxycholic acid in, and the cholesterol saturation of, bile and induces the formation of gallstones. Prolongation of intestinal transit has been proposed as the mechanism for the increase in the proportion of deoxycholic acid in bile. AIMS: To study the effects of octreotide on intestinal transit in acromegalic patients during octreotide treatment, and to examine the relation between intestinal transit and bile acid composition in fasting serum. METHODS: Mouth to caecum and large bowel transit times, and the proportion of deoxycholic acid in fasting serum were measured in non-acromegalic controls, acromegalic patients untreated with octreotide, acromegalics on long term octreotide, and patients with simple constipation. Intestinal transit and the proportion of deoxycholic acid were compared in acromegalic patients before and during octreotide. RESULTS: Acromegalics untreated with octreotide had longer mouth to caecum and large bowel transit times than controls. Intestinal transit was further prolonged by chronic octreotide treatment. There were significant linear relations between large bowel transit time and the proportion of deoxycholic acid in the total, conjugated, and unconjugated fractions of fasting serum. CONCLUSIONS: These data support the hypothesis that, by prolonging large bowel transit, octreotide increases the proportion of deoxycholic acid in fasting serum (and, by implication, in bile) and thereby the risk of gallstone formation.  (+info)

Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. (4/712)

BACKGROUND: Prucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans, with gastrointestinal prokinetic activities in vitro. AIMS: To evaluate the effects of prucalopride on gastrointestinal and colonic transit. METHODS: A validated scintigraphic technique was used to measure gastrointestinal and colonic transit over 48 hours in 50 healthy volunteers. For seven days, each subject received a daily dose of 0. 5, 1, 2, or 4 mg prucalopride, or placebo in a double blind, randomised fashion. The transit test was performed over the last 48 hours. RESULTS: There were significant accelerations of overall colonic transit at 4, 8, 24, and 48 hours (p<0.05) and proximal colonic emptying t1/2 (p<0.05). The 0.5, 2, and 4 mg doses of prucalopride were almost equally effective and accelerated colonic transit compared with placebo. Prucalopride did not significantly alter gastric emptying (p>0.5) or small bowel transit (overall p=0. 12). The medication appeared to be well tolerated during the seven day treatment of healthy subjects. CONCLUSION: Prucalopride accelerates colonic transit, partly by stimulating proximal colonic emptying, but does not alter gastric or small bowel transit in healthy human subjects. Prucalopride deserves further study in patients with constipation.  (+info)

Gastric emptying and intestinal transit of pancreatic enzyme supplements in cystic fibrosis. (5/712)

OBJECTIVE: To investigate gastric emptying and intestinal transit of pelleted pancreatin in relation to food boluses. METHODS: Dual isotope scintigraphy combined with breath hydrogen sampling was used to track the concurrent gastric emptying and intestinal transit of 111indium labelled microspheres and a 99mtechnetium labelled tin colloid test meal. Twelve pancreatic insufficient cystic fibrosis patients aged 5 to 38 years performed the study. RESULTS: 50% gastric emptying times showed patient to patient variation. The mean discrepancy in 50% gastric emptying times between the two labels was > 67 minutes. Mean small bowel transit time for the food bolus was prolonged at 3.6 minutes. A significant correlation was seen between weight standard deviation score and 50% emptying time for pancreatin (r = +0.73). CONCLUSION: Gastric mixing of food and pancreatin may be limited by rapid emptying of microspheres. Patients with high dosage requirements could benefit from changing the pattern of their pancreatin supplementation.  (+info)

Randomised controlled trial of trophic feeding and gut motility. (6/712)

OBJECTIVES: To determine the effect of trophic feeding on gastric emptying and whole gut transit time in sick preterm infants. METHODS: A randomised, controlled, prospective study of 70 infants weighing less than 1750 g at birth, who were receiving ventilatory support, was performed. Group TF (33 infants) received trophic feeding from day 3 (0.5 ml/h if birthweight less than 1 kg, 1 ml/h if greater or equal to 1 kg) in addition to parenteral nutrition until ventilatory support finished. Group C (37 infants) received parenteral nutrition alone until ventilatory support finished. Expressed breast milk or a preterm formula were given according to maternal preference. Gastric emptying was assessed within 24 hours of nutritive milk feeding equal to 90 ml/kg/day, using ultrasound scans to measure the reduction in the gastric antral cross sectional area after a feed. Whole gut motility was assessed at both 3 and 6 weeks of age by measuring the whole gut transit time (WGTT) of the marker carmine red. RESULTS: There was no significant difference between groups in their gastric half emptying time, median difference (95% confidence interval) 2.6 (-5.9, 13.9) minutes. The WGTT was significantly faster (p < 0.05) in group TF at both 3 and 6 weeks; median difference -13 (-47, -0.1) and -12.5 (-44, -0.5) hours, respectively. CONCLUSIONS: Trophic feeding enhances whole gut motility but not gastric emptying. This effect could subsequently improve milk tolerance in sick preterm infants.  (+info)

Visual parameters define the phase and the load of contractions in isolated guinea pig ileum. (7/712)

How the movements of the intestinal walls relate to luminal pressures and outflow remains incompletely understood. We triggered the peristaltic reflex in the isolated ileum of the guinea pig and quantified wall movements through computerized measurements of diameter changes. Contractions developed as indentations close to the upstream end of the loop. The indentations deepened and expanded in length. The downstream shoulder of contractions started and stopped to propagate before the upstream shoulder. Shoulders differed in their length and gradient over most of the duration of the contraction, and this gives the contraction an axial asymmetry. Over the course of individual contractions, the length of the indented segment correlated well with the luminal pressure. Contractions in response to large volumes generated long indented segments and high luminal pressures. The onset and the end of pressure waves and of outflow did not necessarily coincide with the onset and end of visual parameters of contractions. These findings indicate that objective visual parameters might be useful to describe and to classify contractions.  (+info)

Modeling intermittent digesta flow to calculate glucose uptake capacity of the bovine small intestine. (8/712)

To test the hypothesis that the uptake capacity of the bovine small intestine for glucose is upregulated to match or slightly exceed glucose delivery, glucose was continuously infused into the proximal duodenum of four cannulated holstein heifers. Every 3 days, infusion rates were increased by an average of 34 mmol/h. A model of glucose disappearance from multiple boluses of intestinal digesta was used to estimate the transporter maximum velocity and functional maximum uptake capacity for the entire small intestine from average ileal glucose flows during the third day of each period. Because of its intermittency, digesta flow remained independent of simulated transit time. For each unit increase in glucose infusion rate, uptake capacity increased by only 0.55 units. Excess capacity for glucose uptake was approximately twofold in forage-fed cattle and declined to below delivery at infusions of >208 mmol/h added glucose, approximately three times the normal load. Calculations for cattle, sheep, and rats indicate that the glucose transport capacity of the small intestine is typically underutilized because of a fraction of time that transporters are not in contact with digesta.  (+info)

The primary aim of this study is to assess the equivalence of SP to ROM through characterization of device agreement using SP cutoffs for colonic and whole gut transit (59hrs and 73 hrs respectively) derived from the above mentioned study. The cutoffs are derived from the 95th percentile of the healthy subjects in the study. Demonstration of agreement will also serve to validate these SP cutoffs. Device agreement will be evaluated by comparing the percentage of subjects identified with slow transit versus normal transit with SmartPill to the percentage of subjects identified with slow versus normal transit with ROM in the study population. The colonic transit time results will serve as the primary measure for slow versus normal transit for SmartPill. For ROM test we will employ the Metcalf protocol which provides a measure of whole gut transit to compare the SmartPill results to. Additionally, we will characterize gastric emptying and small bowel transit time of the SmartPill in this population. ...
The effect of chilli powder and its pungent ingredient capsaicin on gastrointestinal transit in the rat was studied. Fasted unanaesthetized male Sprague-Dawley rats (n = 144) received by gavage a test meal containing charcoal and cellulose in water or capsaicin solvent plus 51Cr as a radioactive marker. Either 100 or 200 mg of chilli powder (containing 0.13 and 0.26 mg of capsaicin, respectively) or 0.5 or 1 mg of capsaicin were added, the final volume of each meal being 1.5 mL. At 10 and 20 min, animals were killed and the amount of isotope that had left the stomach was measured, together with the distance the charcoal column had travelled along the small intestine. Compared to controls, animals given chilli powder emptied less of their gastric content at 10 and 20 min, an effect partly reproduced by capsaicin. However overall gastric-small intestinal transit was unaffected by chilli powder or capsaicin. Another 12 male Sprague-Dawley rats received, under light ether anaesthesia, on six ...
Looking for bowel transit time? Find out information about bowel transit time. sequential arrangement of all events, or the interval between two events in such a sequence. The concept of time may be discussed on several different... Explanation of bowel transit time
A bowel transit time test measures how long it takes for food to travel through the digestive tract. After you chew and swallow your food, it moves into your stomach, where it is mixed with acid and digestive enzymes. After your food leaves your stomach, it is squeezed through your small intestine, where nutrients are absorbed for use by your body. The food then goes into your large intestine (colon) where water is absorbed. Whatever hasnt been digested and absorbed by your intestines combines with bacteria and other waste products and becomes stool (feces). Stool is expelled from your body through your anus. The time it takes for food to travel from your mouth through your digestive tract to your anus is your bowel transit time. Sometimes, just the time it takes for food to travel through the colon is measured. This is called the colonic transit time.. Bowel transit time depends on what types of food you eat and how much you drink. For example, people who eat lots of fruits, vegetables, and ...
Objective methods for examination of pouch function are warranted for a better understanding of the functional result and treatment of dysfunction. The objective of this study was to evaluate the results of scintigraphic intestinal transit time and defaecography compared to the results of pouch function, mucosal condition and a questionnaire on quality of life (QoL). This cross-sectional study included 21 patients. Scintigraphic transit time and defaecography was determined with the use of Tc-99m. Pouch function was assessed by number of bowel movements, pouch volume, and continence. Pouch mucosal condition was evaluated by endoscopy and histology. Median transit time was 189 min (105-365). Median ejection fraction at defaecography (EF) was 49% (3-77) and 62% (17-98) after first and second defecation. Median pouch volume was 223 mL (100-360). A median daily stool frequency of nine (4-25) was reported and three (14%) patients suffered from daytime incontinence. No patients had symptomatic or endoscopic
The effect of an infusion of two doses of peptide YY (PYY), a novel putative gastrointestinal hormone, has been assessed on mouth to caecum intestinal transit time and on the rate of gastric emptying after ingestion of an inert 200 ml liquid meal thought unlikely to interrupt fasting gastrointestinal motility patterns. A low dose of PYY was chosen to give plasma concentrations within the range seen postprandially in healthy subjects, while the high dose mimicked the raised levels seen in several malabsorptive conditions. During infusion of PYY at 0.18 pmol/kg/min plasma concentrations rose from a basal of 8 +/- 2 pmol/l to 38 +/- 5 pmol/l and at 0.51 pmol/kg/min to 87 +/- 10 pmol/l. Mouth to caecum transit time was delayed from 67 +/- 4 mins on the saline infusion day to 94 +/- 7 mins (p less than 0.01) on the low dose and 192 +/- 9 mins (p less than 0.001) on the high dose infusion day. Time to 50% gastric emptying was prolonged from 37 +/- 8 mins during saline infusion to 63 +/- 10 mins (p ...
F-004-009 The SDEIS states that Since transit routes are designed to serve trips to downtown, while the tunnel is designed to serve trips through downtown, the impact of tolls on transit is negligible (p. 215). This is simplistic and inaccurate. First, much transit does indeed serve trips through downtown both by design and necessity, sometimes directly and sometimes through connections. Second, the extent tolling affects the ability of transit to operate effectively - that is, if tolling affects access, reliability or travel time - it obviously affects ridership.. ….. The SDEIS finds the impact of tolling on transit ridership to be negligible (p.215). However, FTA believes the assessment of the effectiveness of priority treatments to be optimistic. More realistic is the depiction of dramatically increased travel time on Second and Fourth Avenues (Exh. 9-15)… The Project should be ensuring that even the most conservative assumptions show increasing transit use and only minimally ...
Montisci, M.J., Dembri, A., Giovannuci, G., Chacun, H., Duchene, D. and Ponchel, G (2001) Gastrointestinal Transit and Mucoadhesion of Colloidal Suspensions of Lycopersicon esculentum L. and Lotus tetragonolobus Lectin-PLA Microsphere Conjugates in Rats. Pharmaceutical Research, 18, 829-837.
If getting a colonoscopy ranks up there with root canals on your list of dreaded procedures, you have plenty of company. But you probably havent heard of the SmartPill or its cousin, PillCam, from Given Imaging Ltd. (NASDAQ: GIVN) of Yoqneam, Israel. The good news is, the SmartPill Wireless Motility Capsule procedure received a new reimbursement code earlier this year. The SmartPill is a sensor-based capsule technology that measures gastric emptying, small bowel transit, colonic transit and whole gut transit times to help with the diagnosis of gastrointestinal conditions and diseases such as Crohns Disease. So the next time your physical rolls around and your doctor mentions that unpleasant procedure, ask about the SmartPill. You may be glad you did…..Want to read more news? Click here for a free trial to The Health Care M&A Information Source and download the current issue today ...
비만한 사람에서 과민성 장증후군이 더 빈번한 이유는 여러 가지가 있겠지만 다음과 같이 정리해 볼 수 있겠다[32]. 첫째, 비만한 사람에서 소장과 대장의 운동 변화가 나타날 수 있다. Basilisco 등[33]은 락툴로즈 호기 검사를 통하여 비만한 사람에서 경구-맹장 통과시간(orocecal transit time)이 지연됨을 보고하였다. 반면 Sadik 등[34]은 과민성 장증후군 환자에서 BMI와 대장 통과시간은 역비례 관계가 있으며 비만한 사람에서 하행결장과 구불결장/직장 접합부 통과시간이 더 빨랐다고 보고하였다. 비록 아직까지 데이터는 충분하지 않지만 이러한 소장과 대장 운동 변화의 결과들은 변비형 혹은 설사형 과민성 장증후군의 병태생리를 설명할 수 있는 근거가 될 수 있으며 향후 더 많은 연구가 필요하겠다. 둘째, 비만인 사람에서 저섬유질과 고탄수화물 식사가 과민성 ...
Grudell AB, Camilleri M, Jensen KL, Foxx-Orenstein AE, Burton DD, Ryks MD, Baxter KL, Cox DS, Dukes GE, Kelleher DL, Zinsmeister AR. Dose-response effect of a beta3-adrenergic receptor agonist, solabegron, on gastrointestinal transit, bowel function, and somatostatin levels in health. American Journal of Physiology. Gastrointestinal and Liver Physiology. 2008 May;294(5):G1114-9. PMID 18372395 ...
Watherian indica is a dicotyledonous shrub used in the treatment of diarrhoea in Northern Nigeria. It consists of a well-defined mixture of flavonoids, saponins, sugars, alkaloids and mucilage. Both in vitro and in vivo experiments of the aqueous extract were done. The study to determine the in vivo effect of aqueous root extract of the shrub was on the gastrointestinal transit in conscious rats. In the in vivo experiment, fasted rats were given 20, 40, 60 and 80 mg/kg of the extract orally and 15 minutes later, 0.5ml of 10% charcoal (BaSO4. H2O) was administered into the conscious animals. The control group received the vehicle (normal saline) before charcoal meal. In the in vitro experiment, the effect of 0.2, 0.4, 0.6 and 0.8mg/ml of the extract on the frequency and strength of contraction of an isolated rabbit jejunum was determined using a multi-channel physiograph (model PMP-4B). The result of the study indicates that Watherian indica root extract delays the gastrointestinal transit and ...
The benefits of strength training are numerous; from helping to prevent illnesses and diseases to better posture and balance, better sleep and the reduction in stress and anxiety.Improved musculoskeletal systemStrength training has profound effects on the musculoskeletal system, as it helps maintain functional abilities and prevents osteoporosis, sarcopenia, lower-back pain and other disabilities.Positively affects health risk factorsSensible strength training involves precise controlled movements for each major muscle group and does not require the use of heavy loads. Research shows that strength training may positively affect risk factors such as insulin resistance, resting metabolic rate, glucose metabolism, blood pressure, body fat and gastrointestinal transit time, which are associated with diabetes, heart disease and cancer. And all the benefits of strength training are likely to be obtained in two 15 to 20 minute training sessions a week.Other benefits of strength training:Enhances performance of
These changes increase the speed of gastric emptying and reduce reflux from the duodenum and the stomach into the oesophagus. Which has been observed radiologically and by other methods PASPERAN simultaneously increases the motor action of the small intestine which results in a decrease in the small bowel transit time ...
Rapid gastric and intestinal transit is a major determinant of changes in blood glucose, intestinal hormones, glucose absorption and postprandial symptoms after
TY - JOUR. T1 - Hillslope permeability architecture controls on subsurface transit time distribution and flow paths. AU - Ameli, A. A.. AU - Amvrosiadi, N.. AU - Grabs, T.. AU - Laudon, H.. AU - Creed, I. F.. AU - McDonnell, J. J.. AU - Bishop, K.. N1 - Acknowledgement We thank James Craig and Jan Seibert for their support throughout the process. This research was funded by NSERC Discovery Grant and NSERC Accelerator to J.J.M, NSERC Discovery Grant to I.F.C. The Krycklan catchment study is supported by the Swedish Science Foundation (VR) SITES, ForWater (Formas), Future Forest, Kempe Foundation, SLU FOMA and SKB.. PY - 2016/12. Y1 - 2016/12. N2 - Defining the catchment transit time distribution remains a challenge. Here, we used a new semi analytical physically-based integrated subsurface flow and advective dispersive particle movement model to assess the subsurface controls on subsurface water flow paths and transit time distributions. First, we tested the efficacy of the new model for ...
A stacked patch antenna has a first element having a feed thereto spaced above a ground plane and one or more spaced apart parasitic elements spaced above the first element. The first and parasitic elements may be tuned to a fundamental mode for radiation of a specified frequency. The geometric centers of the parasitic elements are offset from one another and from the geometric center of the first element along the same direction. The stacked patch configuration provides increased gain and bandwidth. The offset configuration determines the direction of maximum gain for the antenna. The first and parasitic elements can be single antenna elements and may be microstrip antenna elements. The elements can also be arrays of microstrip antenna elements. The phasing of the arrays of microstrip elements can be controlled to determine a gain sensitivity direction.
If youve read about me in any way, youll likely know about my issue with the Surrey at-grade rail (Light Rail Transit) proposal. It was the turnkey issue that became responsible for dragging me into a world of politics. As a stakeholder, it motivated me to educate myself as best as I could about issues in the community, and is the reason why I pay attention.. My problem with Light Rail? As much as everyone seems to like the option - especially over a SkyTrain expansion - and as much as it DOES work well in many locations around the world, the reality of Light Rail in Surrey is that it wont help us achieve ambitious goals (rather restricting us from getting to them ever); wont move our people the most efficiently; and wont give us the most benefits for the cost.. These arent wild claims; these are facts and stats that have been made clear in numerous studies, including TransLinks Surrey Rapid Transit Study. So far, people across the city of Surrey - from stakeholders to big advocacy ...
If youve read about me in any way, youll likely know about my issue with the Surrey at-grade rail (Light Rail Transit) proposal. It was the turnkey issue that became responsible for dragging me into a world of politics. As a stakeholder, it motivated me to educate myself as best as I could about issues in the community, and is the reason why I pay attention.. My problem with Light Rail? As much as everyone seems to like the option - especially over a SkyTrain expansion - and as much as it DOES work well in many locations around the world, the reality of Light Rail in Surrey is that it wont help us achieve ambitious goals (rather restricting us from getting to them ever); wont move our people the most efficiently; and wont give us the most benefits for the cost.. These arent wild claims; these are facts and stats that have been made clear in numerous studies, including TransLinks Surrey Rapid Transit Study. So far, people across the city of Surrey - from stakeholders to big advocacy ...
Average transit time through the colon is generally thought of as 30-40 hours which is in line with your first posting. Thats why I thought you were...
Cancer thrives on sugar. Regular exercise reduces your insulin levels, which creates a low sugar environment that discourages the growth and spread of cancer cells. Controlling your insulin levels is one of the most powerful steps you can take to reduce your cancer risk. Physically active adults experience about half the incidence of colon cancer as their sedentary counterparts. Exercise has a beneficial influence on insulin, prostaglandins and bile acids, all of which are thought to encourage the growth and spread of cancer cells in your colon. Exercise also improves bowel transit time, which means your body s waste is spending less time in contact with the mucosal lining of your colon. As the Wall Street Journal article points out, women who exercise regularly can reduce their breast cancer risk by 20 to 30 percent over their inactive counterparts. This is likely due to a lowering of estrogen levels. The article cites a study in which women being treated for breast cancer were 50 percent less ...
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In order to optimize the satiating potency of triacylglycerols, we previously performed a study in which we varied the location of fat infusion, showing that activation of the ileal brake by ileal fat infusion reduced food intake by an additional 12 % compared to the same emulsion infused in the duodenum, thereby demonstrating the potency of the ileal brake to reduce food intake and satiety ...
The gut microbiota of humans and other animals comprises more than a thousand microorganisms (Cho and Blaser, 2012; Lakshminarayanan et al., 2014). Most of these microbes reside in the ileum and colon. Their primary function is to ferment carbohydrates and proteins that are not digested in the upper gut into absorbable energy. Other functions of these bacteria include producing vitamins (B and K), protecting against pathogens, mediating innate and adaptive immune responses, and metabolizing orally administered natural products and drugs.. The composition of the gut microbiota, as well as the residence of specific bacterial species, is affected by pH, diet, the use of antibiotics, the presence of digestive enzymes, and the redox potential of the tissue and gut transit time (Oktyabrsky and Smirnova, 1989; Nord, 1990; Aguilera et al., 2013; Xu et al., 2014a). Conditions are extremely variable in the gastrointestinal tract, mouth, pharynx, esophagus, stomach, small intestine, and large intestine. ...
If you are serious about protection, the Transit Case provides unparalleled security for your gear. It is built waterproof, dustproof and shockproof using the highest quality ABS materials so you can take your most sensitive equipment anywhere, regardless of the conditions. Plus, our unique retractable handle and ball bear wheels make your trek a lot easier, no matter where your journey takes you. Transit Cases utilize high-impact ABS resin which resists cracking and damages due to cold weather and is also repairable in the field. Case accessories also available. View Load Out/Transit Case Accessories here. ...
Direct measurement of transit time in the stomachs and intestine of dairy cows. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Food transit through the small intestine affects the bodys absorption of nutrients and, consequently, our health. The discovery that food transit time is regulated by a hormone indicates new ways to increase the intestinal ...
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A stent may comprise a plurality of interconnected struts including a central strut, a first strut on one side of the central strut and a second strut on the other side of the central strut, where a portion of one side of the central strut is nested within the first strut and a portion of the other side of the central strut is nested within the second strut. The nested portions of the central strut are more radiopaque than the remainder of the central strut. A cover may be disposed about the stent in the region of the central strut.
Beginning with the 2011 Happy Valley Park-and-Ride, at I-17 and Happy Valley Road, Lucking designed the waterjet-cut patterns of the shade panels to illustrate cars, bicycles, and buses traveling the curving mountain roads of north Phoenix. She also worked with the design team to integrate custom fencing, free-standing screens, and scored concrete into the transit campus. For the second in the Shade for Transit series, the 27th Avenue and Baseline Road Park-and-Ride, Lucking drew upon the ranching history of Laveen, depicting cowboys waiting along a fence - like other transit riders - for the bus to arrive. For the latest in the series of park-and-rides, at 24th Street and Baseline Road, Lucking created images inspired by the agricultural history of the Japanese flower gardens that once lined Baseline Road ...
DOCTYPE html, ,html, ,head, ,meta name=viewport content=initial-scale=1.0, user-scalable=no, ,meta charset=utf-8, ,title,Transit layer,/title, ,style, /* Always set the map height explicitly to define the size of the div * element that contains the map. */ #map { height: 100%; } /* Optional: Makes the sample page fill the window. */ html, body { height: 100%; margin: 0; padding: 0; } ,/style, ,/head, ,body, ,div id=map,,/div, ,script, function initMap() { var map = new google.maps.Map(document.getElementById(map), { zoom: 13, center: {lat: 51.501904, lng: -0.115871} }); var transitLayer = new google.maps.TransitLayer(); transitLayer.setMap(map); } ,/script, ,script async defer src=https://maps.googleapis.com/maps/api/js?key ...
Dart Transit has had improved uptime and fewer tows on its fleet of 300 Kenworth T680s running the remote diagnostics program Kenworth TruckTech+.
This report by Transportation for America with the Center for Neighborhood Technologies (CNT), examines transit services, and their relationship to an aging population.
The transit agency officially ends its long-term deal to buy expensive, foreign-made buses. Plus, Perata and De La Fuentes newest questionable deal.
Rabbit Transit Atari 2600 Starpath Supercharger Game Produced by: Starpath Model#: AR4104 Atari Rarity Guide|Rarity: 6 Rare+ Imagine Frogger with a much...
Olivia Chow remains highly skeptical about how John Tory will build, pay and proceed with his proposed SmartTrack transit plan, but her mayoral rival says that her criticisms are rooted in...
Murphy says revitalizing NJ Transit is one of his to priorities and his new budget contains $242 million in new money for the agency.
/PRNewswire/ -- Transit Scientific announced completion of the first clinical cases in the world using the XO Cross® Microcatheter platform. Dr. James McGuckin...
TVF is a new vascular function that simplifies the assessment of the peripheral vascular tree. More specific TVF provide a specific support for assessment of Below-Knee stenosis.
Sarah still believed she could make it off the bus without pissing herself. The doors were right there and if she could somehow unclench long enough to propel her body to the front of the bus, maybe she could haul ass off of it in time. On nights like this one, after surviving the hellish shift that she had, Sarah figured karma owed her one. Shit, her whole life was already like one of those Cracker Jack prizes-useless crap getting in the way of what youre really after.
H.R. 4001. To amend titles 23 and 49, United States Code, with respect to bikeshare projects, and for other purposes. In GovTrack.us, a database of bills in the U.S. Congress.
The lipid-rich membranes of cells are largely impermeable to proteins, but evolution has provided a way through - in the form of transmembrane tunnels. A new study shows in unmatched detail what happens as proteins pass ...
Koop Im Feeling U van Transit MP3 download online 7digital België - Ruim 25 miljoen tracks van hoge kwaliteit in onze winkel
TY - JOUR. T1 - Effect of Glepaglutide, a Long-Acting Glucagon-Like Peptide-2 Analog, on Gastrointestinal Transit Time and Motility in Patients With Short Bowel Syndrome. T2 - Findings From a Randomized Trial. AU - Hvistendahl, Mark Krogh. AU - Naimi, Rahim Mohammad. AU - Enevoldsen, Lotte Hahn. AU - Madsen, Jan Lysgaard. AU - Fuglsang, Stefan. AU - Jeppesen, Palle Bekker. N1 - © 2020 American Society for Parenteral and Enteral Nutrition.. PY - 2020/11. Y1 - 2020/11. N2 - BACKGROUND: Patients with short bowel syndrome (SBS) and distal-bowel resections lack neuroendocrine feedback regulations, potentially resulting in rapid gastrointestinal (GI) transit. The objective was to assess the efficacy of glepaglutide, a long-acting glucagon-like peptide-2 analog, on GI transit in patients with SBS.METHODS: In this single-center, double-blind, dose-finding, phase 2 trial, patients with SBS were randomly assigned to 3 treatments (0.1, 1, and 10 mg) in a 2-period crossover design. Each treatment period ...
Loperamide improves anorectal function in patients with chronic diarrhoea. We wished to investigate whether the prodrug loperamide oxide has similar effects. Eleven patients with chronic diarrhoea and faecal incontinence participated in a randomized, placebo-controlled, double-blind, crossover study of the effects of loperamide oxide (4 mg twice daily for 1 week). Loperamide oxide reduced wet stool weight and improved the patients ratings of symptoms. Mouth-to-caecum transit time was not altered, but whole-gut transit time was prolonged. There were limited effects on anorectal function, but the mean minimum basal pressure mainly contributed by the internal anal sphincter (IAS) was increased, as was the mean volume infused before leakage occurred in the saline continence test. Loperamide oxide is effective in the treatment of diarrhoea with faecal incontinence; normalization of colon transit time and an increase in the tone of the IAS seem to be the main determinants of efficacy. ...
Constipation is a commonly diagnosed gastrointestinal disorder with an estimated prevalence in the general population of 12-19%, which results in lower quality of life and significant healthcare costs to the individual. Almost 9 in 10 physician visits for constipation result in a laxative prescription. Additionally, consumers in the USA and in the United Kingdom spend almost 1 billion dollars annually for over-the-counter laxatives. Chronic constipation is diagnosed almost solely on patient symptoms, which generally includes unsatisfactory defecation due to infrequent stools, difficult stool passage, or both. The cause of chronic constipation is unknown and likely multifactorial with physiological changes, psychological factors, and lifestyle influences identified as possible culprits. Consequently, identification of effective constipation treatments remains a challenge.. The initial management of constipation symptoms is focused on evaluating lifestyle and diet variables as possible culprits. ...
To the best of the authors knowledge, this is the first WGCNA-based bioinformatics study for an STC-associated miRNA expression profile (GSE57969) in the GEO platform. This study provided unique insights and meaningful evidence of potential miRNAs, genes and pathways involved in the pathogenesis of STC. The GEO platform was utilized for these studies, which has the only gene expression profile and miRNA expression profile on STC. Previous bioinformatics studies related to STC currently remain limited. Specifically, Liu et al (17) discovered a significant negative correlation between miRNA-128, and colonic macrophage numbers during the pathogenesis of STC. Other studies that have focused on STC were primarily associated with clinical practice, with sparse investigation into genomic expression profiles (2-5). In summary, this is the first study on the bioinformatic analysis of miRNA expression profile in STC. Of note, the original article on GSE57969 showed that miR-128 is significantly decreased ...
In order to propel the contents of the bowel forward the intestines undergo a sequence of rhythmic strong muscular contractions known as peristalsis. These movements are coordinated by a nerve plexus located within the intestinal wall known as enteric nervous system (ENS).
Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated using pharmacokinetic models describing plasma concentrations of drugs from various enteric-coated pellet formulations. Gastric emptying time, lag time of emptying, and drug release rate from pellets in the small intestine, along with other pharmacokinetic parameters of drugs, were used to construct pharmacokinetic models. The models were then evaluated by comparing simulated plasma concentrations of model drugs from Monte Carlo simulations to observed plasma concentrations of these drugs from the literature. Results showed that the models described plasma concentrations of drugs from enteric-coated pellet formulations very well. Pharmacokinetic models describing plasma concentrations of drug from mixed immediate-release and enteric-coated pellet formulations were also used in simulations of bioequivalence studies. Results from the research are very useful in designing ...
It was announced today that AMITIZA (lubiprostone), 24-mcg soft-gel capsules, approved by the U.S. Food and Drug Administration (FDA) in January 2006, is now available by prescription in pharmacies across the United States for the treatment of chronic idiopathic constipation in adults. AMITIZA (pronounced ahm-e-TEASE-a) is the first selective chloride channel activator approved for therapeutic use in chronic idiopathic constipation, a condition that affects both men and women and affects patients over the age of 65 more frequently ...
The influence of octreotide on gastric emptying after pancreatic surgery is unknown. In this study we found that octreotide, in a clinically used dosage (100 μg three times daily), accelerates gastric emptying in healthy volunteers. The increase in gastric emptying was partly caused by a shorter lag phase. These results are in accordance with previous studies, which used either oral SMS products, or lower, single subcutaneous dosage administrations.22 23 Our results suggest that a delay in gastric emptying, as reported for a continuous subcutaneous octreotide infusion rate of 0.83 μg/kg/h in dogs,27which corresponds to a dose of approximately 500 μg three times daily in humans, is not induced by dosages administered after pancreatic surgery (100 μg three times daily).. Because gastric emptying rate after octreotide treatment was accelerated, small bowel transit time was delayed much more than the 80 minute difference of total mouth to caecum transit time. To obtain an indication of small ...
The paracetamol (PCM) and sulfapyridine (SP) double marker technique is based on combined gastric administration of PCM and sulfasalazine followed by plasma concentration measurements for PCM and SP. PCM is rapidly absorbed from the duodenum and can be regarded as a marker for gastric emptying (GE). Sulfasalazine is poorly absorbed from the small intestine but is extensively metabolized in the colon by bacteria into SP. As SP is only absorbed from the colon it serves as a marker for small intestinal transit time (SITT). The double marker method is used to identify and characterize effects on GE and SITT. The aim of the present investigation was to demonstrate how semi-mechanistic modeling of PCM and SP could facilitate characterization and the understanding of pharmacologically induced changes in GI transit under fed and fasting conditions. Two double marker validation studies were performed in dogs with erythromycin (1 mg/kg) and atropine (0.06 mg/kg), both of which have been described to ...
Breath gas contains a range of marker gases that can be associated with disease and metabolism. For instance, the monitoring of breath H2 is useful for measurement of orocecal transit time, colonic fermentation, abnormal fermentation and irritable bowel syndrome.
The effect of morphine (0.1 mg/kg) on insulin secretion stimulated by oral, intraduodenal, or intravenous administration of glucose was studied in seven healthy volunteers. When glucose was given intravenously, morphine had no effect on plasma glucose, insulin, glucose-dependent insulinotropic polypeptide (GIP), or pancreatic glucagon. Following oral glucose, morphine slowed gastric emptying and reduced plasma concentrations of glucose, insulin, and GIP. During intraduodenal infusion of glucose, insulin concentrations in plasma were also decreased by morphine, an effect best explained by decreased small intestinal transit with delayed absorption of glucose and delayed release of GIP. We conclude that clinically relevant doses of morphine have no direct effect on insulin secretion and that the changes observed were secondary to slowed gastric emptying and small intestinal transit.. ...
Cerclage was done at 22 weeks of my pregnancy for a 1 cm short cervix, but then I lost both babies at 23 weeks because of premature birth. However, as fibroids persist or increase in size symptoms can include: heavy/painful menstrual periods, abdominal or pelvic pain, increased urinary frequency, painful intercourse and even infertility. Fibroids are rarely cancerous, but they can make a womans life a misery in spite of this. Some patients with cystic fibrosis have prolonged small intestinal transit times. Performed using general anesthesia, iodine and uterine fibroids is usually done on an outpatient basis.
The aim of this study was to investigate the effects of Pu-erh tea on activated carbon-induced constipation in ICR mice. The changes in body weight, dietary intake, gastrointestinal transit, first black stool defecation time, number and weight of feces, water content of feces and various levels of substances in serum were used to evaluate the anti-constipation effects of Pu-erh tea. Body weight, dietary intake and the amount of water consumed by mice decreased with activated carbon-induced constipation and those of the sample treated group mice were higher than the control group mice. The first black stool time of normal, control, bisacodyl (100 mg/kg) and 200, 400 and 800 mg/kg Pu-erh tea treated mice were 90, 221, 118, 178, 155 and 139 min, respectively. Following oral administration of 200, 400 and 800 mg/kg of Pu-erh tea and 100 mg/kg of bisacodyl, the gastrointestinal transit rates were shortened by 48.6, 59.6, 78.0 and 91.9%, respectively. Serum levels of motilin (MTL), gastrin (Gas), ...
A solid dosage form designed to facilitate rapid and reliable oral, esophageal and GI transit has a surface area of the contact patch, i.e., the area of contact between the dosage form and the bodily
Hi All, Im new to this forum. I have been diagnosed with IBS/Chronic idiopathic constipation. I am at a loss as to what to do. The strangest thing about my problem is that it seemingly came out of...
This module discusses the impact of chronic idiopathic constipation on patients and the NHS, and reviews the currently available methods of diagnosis
Are you living with Chronic Idiopathic Constipation (CIC)? This guide to triggers, medications and lifestyle remedies will help you to manage your condition well.
DiPiro JT. DiPiro J.T. DiPiro, Joseph T.. Plecanatide, a New Therapeutic Option for Chronic Idiopathic Constipation. Pharmacotherapy Updates DiPiro JT. DiPiro J.T. DiPiro, Joseph T. New York, NY: McGraw-Hill, 2016, http://accesspharmacy.mhmedical.com/updatesContent.aspx?gbosid=325601§ionid=151277853. ...
Minister for TransLink Peter Fassbender says Metro Vancouver mayors need to suck it up and approve a modest increase in TransLink taxes to cover the regions share of launching an ambitious transit expansion plan.. Some Metro mayors are reluctant to okay more funding for a first phase of expansion without certainty that the rest of their 10-year plan will get full support from the federal and provincial governments.. Fassbender told Black Press they need to get over that and deliver funding for phase one of the plan, which has 50 per cent contributions from Ottawa and one-third from the province.. What they need to do, quite honestly, is to suck it up and to get on with phase one, he said.. RELATED: NDP promises to boost transit cost sharing if elected TransLink boss maps out transit surge option Fassbender said theres no way for B.C. or Ottawa to provide ironclad guarantees that subsequent phases will be fully funded.. I cant hold future governments to anything other than what we can do ...
Psyllium seed husks are not digestible in humans and are often used as a source of dietary fiber without calories. Mixed with water and allowed to swell, they are used to relieve constipation as well as part of treatment for a variety of more serious bowel complaints. With the problematic lack of fiber in todays diet, Psyllium is a good source of fiber to promote GI (gastrointestinal) transit time and overall intestinal health. It is also considered a prebiotic.*. ...
A wheel of a unicycle has two beams disposed in parallel in a rim. A bolt is extended between the beams. The head of the bolt is disposed away from the geometric center of the wheel and the bolt extends through the geometric center of the wheel. Two plates which are connected together by a nut are slidably disposed between the beams. The bolt is engaged with the nut. An axle is extended outward from each plate. A rotation of the head of the bolt causes the axles to move either away or toward the geometric center of the wheel.
Researchers in the Pankaj Jay Pasricha Lab are interested in the molecular mechanisms of visceral pain and restoration of enteric neural function with novel strategies, including neural stem cell transplants. Recent research has focused on the enteric nervous system and gut-brain axis, and the complexity of pain in chronic pancreatitis. Another recent study indicates that patients with underlying small intestinal bacterial overgrowth have significant delays in small bowel transit time as compared to those without, while another explored the safety and efficacy of carbon dioxide cryotherapy for treatment of neoplastic Barretts esophagus.. Research Areas: gastroenterology, stem cells, neurogastroenterology, pancreatitis, pain, Barretts esophagus, motility disorders ...
Researchers in the Pankaj Jay Pasricha Lab are interested in the molecular mechanisms of visceral pain and restoration of enteric neural function with novel strategies, including neural stem cell transplants. Recent research has focused on the enteric nervous system and gut-brain axis, and the complexity of pain in chronic pancreatitis. Another recent study indicates that patients with underlying small intestinal bacterial overgrowth have significant delays in small bowel transit time as compared to those without, while another explored the safety and efficacy of carbon dioxide cryotherapy for treatment of neoplastic Barretts esophagus.. Research Areas: gastroenterology, stem cells, neurogastroenterology, pancreatitis, pain, Barretts esophagus, motility disorders ...
OBJECTIVE: To evaluate the effects of retrograde colonic electrical stimulation (RCES) with trains of short pulses and RCES with long pulses on colonic transit in irritable bowel syndrome (IBS) rats and to investigate whether stress-induced visceral hypersensitivity could be alleviated by RCES so as to find a valuable new approach for IBS treatment. METHODS: A total of 48 male rats were randomly divided into model group and control group. Visceral hypersensitivity model was induced by a 6-day HIS protocol composed of two stressors, restraint stress for 40 min and forced swimming stress for 20 min ...
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The overall consequence of these draconian cuts will be dramatically less productive service from the nations largest transit provider in a city that relies completely on transit.. These are incredibly scary cuts, especially in light of the fact that the system is unable at the moment to fund its next 5-year plan. Something must be done.. MTA leaders are suggesting that the only way to avert the proposed cuts is to demand more money from the city and state. But the fact is that both of those levels of government are also facing dramatic cuts - and they dont have the ability to increase funding. So the only real place to turn is Washington. The federal government must take a position and increase funding.. -. This is especially true for a very simple reason: New York Citys farebox recovery ratio is higher than that of any other transit system in the country. What does this mean? More of the system is paid for directly through fares - 67% - than anywhere else in the United States, and the ...
Untitled Document Underwater Kinetics has two tough options for transporting and storaing your larger equipment and gear. The Transit™ Case and the Loadout™ Case are Underwater Kinetics extra large hard protective transport case lines. The UK Transit™ and Loadout™ cases come in exactly the same shape and sizes, but are made from different resins. Transit Case vs. Loadout Case: The Difference The Transit™ Cases are constructed with ultra-solid, high-impact ABS resin. ABS is exceptionally durable, tough, and better resists becoming brittle in cold, harsh weather. ABS resin is field repairable and interior components can be solvent welded to the case shell. Transit Cases are also made with silicone O-rings for a superb watertight seal. The Loadout™ Cases are made from automobile grade, micro-cellular foamed, reinforced polypropylene resin. This results in a case that is lighter in weight and more chemically resistant. The design of the
More than 30 members of Congress, including U.S. Reps. Ayanna Pressley (D-MA), Jesus Chuy Garcia (D-IL), and Hakeem Jeffries (D-NY), introduced legislation on Thursday calling for equal funding for transit and highways.. Called the Transit Parity Resolution, the legislation would change how Congress determines to fund highways and public transportation. Currently, Congress uses a formula set in 1982 that allocates 80 percent of federal transportation dollars to highways, and the remaining 20 percent to public transit. The resolution calls for transit funding to be equal to highway funding.. Public transit is a public good, and its past time our government treat it like one, Pressley said. For too long, our federal transportation investments have prioritized highways over public transit, incentivizing travel in private cars, which increases traffic congestion, produces pollution, and exacerbates racial and economic inequality.. The resolution is supported by several transportation ...
Little is known about how milk proteins affect gastrointestinal (GI) transit, particularly for the elderly, in whom digestion has been observed to be slowed. We tested the hypothesis that GI transit is faster for whey than for casein and that this effect is accentuated with hydrolysates, similar to soy. Adult male rats (18 months old) were fed native whey or casein, hydrolyzed whey (WPH) or casein ...
Cameron Diaz Sex Bad Teacher When youre looking for teacher wild and hot moms, then this is the place for you! Watch 1000s of free online teacher videos everyday! Al Ghazaly School Wayne Nj gave his senior students at Al-Ghazaly High School in Wayne an assignment to. What Is a Masters in Radiology? During your studies in a Masters in Radiology program, you might expect to explore the imaging and radiologic sciences. Students may learn about different types of imaging technology and how to properly use them. These could include ultrasound, magnetic resonance imaging , X-ray and.. Your doctor has recommended that you have a Nuclear Medicine Colonic Transit Study. This is a week long procedure. It is advisable that you do not take laxatives on.. Welcome to radiology-courses.com, the website for the distinctive radiology teaching courses that are provided in London by Drs Simon Morley, Lol Berman and Gerald de.. Radiographers use different kinds of radiation to treat ill or injured ...
Untitled Document Underwater Kinetics has two tough options for transporting and storaing your larger equipment and gear. The Transit™ Case and the Loadout™ Case are Underwater Kinetics extra large hard protective transport case lines. The UK Transit™ and Loadout™ cases come in exactly the same shape and sizes, but are made from different resins. Transit Case vs. Loadout Case: The Difference The Transit™ Cases are constructed with ultra-solid, high-impact ABS resin. ABS is exceptionally durable, tough, and better resists becoming brittle in cold, harsh weather. ABS resin is field repairable and interior components can be solvent welded to the case shell. Transit Cases are also made with silicone O-rings for a superb watertight seal. The Loadout™ Cases are made from automobile grade, micro-cellular foamed, reinforced polypropylene resin. This results in a case that is lighter in weight and more chemically resistant. The design of the Loadout™ Case,
Results Intestinal adaptation is affected by many factors, including remaining bowel length, the presence of the ileocaecal valve and colon, underlying disease process, nutritional status, hepatobiliary function, and bacterial flora. Lengthening techniques do not affect the absorptive surface, although changes in the microvilli have been observed in animal models. Dilated dysmotile intestinal segments benefit from tapering because reduction in the intestinal lumen calibre allows better peristalsis, as demonstrated by improvements in intestinal transit time. Tapering also helps prevention of stasis and subsequently reduction of bacterial overgrowth. Additionally, reduction in bowel diameter decreases the volume to surface ratio, theoretically allowing for more effective contact of the chime with the absorptive surface.. ...
I assume there is no evidence for diabetes or H pylori disease. Have you had a bowel transit study done? Localized neuropathy would be unusual but possible if nothing else is found. I would...
All opioids, especially following clinical circum- stances are completely replaced surgery Hypertriglyceridaemia. Radioactive iodine by tremor which can be referred to be essential under the enzyme inhibitors on bowel transit time. 3-dehydroretinol is generally high doses being treated with crohns previously and prednisone methylprednisolone Atropine is needed. narrow therapeutic index in relation to theophylline Acid diffuses easily crushed or proton-pump inhibitors and analgesic combinations. As in prolonging survival - common traditional agents, a high ACEI lower blood cells that act as necessary. In anaesthesia, barbiturates, which bicarbonate causes of blocking activity. Arguably the plasma bicarbonate, permitting very effective in the methylation of the body into the urine. All opioids, especially following clinical circum- stances are completely replaced surgery. Cidofovir is initiated with a competitive inhibitor of vascular smooth muscle is determined by drug can i drink alcohol while ...
Synergy Pharmaceuticals announced that plecanatide, its investigational oral drug for the treatment of chronic idiopathic constipation (CIC), was well tolerated and met the primary and key secondary endpoints of a Phase 2b/3 clinical study.
Ford Transit Compact 2000 Battery. Find out about Ford Transit Compact 2000 Battery, warning signs, symptoms, diagnosis, and treatment options. New potential method of Ford Transit Compact 2000 Battery. Management of Ford Transit Compact 2000 Battery. The aim of diabetes treatment is to keep you in addition to possible, and reduce the chance of damage. A Remedy for Type 2 Diabetes? A current study suggests there could be a much better treatment for one of the worlds most common diseases.
around two and a half hours to make it into the office. When I finally got there, I realized most employees stayed home to avoid getting stuck in the snow. Luckily, HR, my manager, and another co-op made it to the office. We went over my onboarding, I looked around the office, I met with the few people who made it in, and I had lunch with everyone there. I had only been there a couple of hours and the snow seemed to be getting worse. I was dreading going back because I knew it was going to be at least another two hours on transit. However, knowing the transit situation, our CEO offered to drive us home. Appnovation did a great job of making me feel comfortable even in a tough time.. After my initial rough day, everything went smoothly. During my training, I was able to shadow a project the team was working on. Everyone was brought on and worked to finish it by the deadline. Being able to shadow and do small tasks allowed me to experience what goes into a bid, what areas to focus on, and also get ...
Everyone who starts to get serious about transportation rediscovers the importance of load factor and tare. Did you deliberately choose an inflammatory summary? The bland summary is that the statistics show that nationwide average transit uses 60% (per passenger) of the energy that is used by cars. Both figures can be improved substantially, but the easy targeting is different.. For low capacity methods like automobiles, you need to eliminate tare weight. That is why the scooters do so much better than autos. They have much less tare weight. There is a lot that can be done in this area.. For high capacity methods like transit, you need to improve load factor (reducing tare is good, but load factor is easier). The figures that you show look like the 2005 US numbers. Load factors have increased dramatically, so transit is probably doing better now. Carrying more passengers increases the energy cost by only a tiny amount. There is still a lot that can be done here.. Then, defeat the imbecile ...
I came down with my first serious case of transit fever (later diagnosed as egressia with complications due to rossiteria) nearly four years ago. The symptoms were brought on by HD 217107, the first candidate planet-bearing star observed by the transitsearch.org network. On the night of August 6th, 2002, photometric data was sent by both an observer in Pleasanton California, and from the KAIT automatic telescope at Lick Observatory. The fits to the radial velocity data indicated that the HD 217107 b transit window was scheduled to begin at 2:40 am PDT, and amazingly, both data sets showed a photometric dip right at the predicted time. To seemingly clinch the case, Debra Fisher also used the Lick 3-meter telescope to obtain five radial velocity measurements of HD217107 during and before the predicted transit ingress. When the spectra were analyzed, the velocities came back with a pattern consistent with the expected Rossiter-McLaughlin effect! [The data is available at this webpage]. To say that ...
Basically, I am not interested in whatever the specific reason is why modern trams are accepted more than buses. And I do not care if you call those reasons cultural or whatever. Maybe buses are superior compared with trams and the US transit planners were right over all the last 70 years. But I see what works and what does not. And in the end the customer, the transit rider, is always right. So I would give them what they buy. If they would love to ride big pink buses with plastic elephants on top, I would try to get some. For the moment (and the last decades at least) it seems they are going for trams. So give them modern trams if you want that they get out from the car. In Munich they want trams and underground trains. Trams with the overall and by far best grades from our riders when asked about the preferred mode of transit vehicles. Even more than our nice and fast and clean and effective wonderful underground metro system. I like our buses, we transport over 400,000 passengers ...
Transit Aware is a service created to help professional transit system managers keep up to date with the latest news they need to operate their systems.. Transit Aware is brought to you by:. ...
CityLabs Eric Jaffe writes: Under existing rules employees who ride public transit can get as much as $130/month in IRS commuter benefits, but people who drive to work and park can get up to $250. Beginning next year this playing field levels out. (Finally!! I worked on this issue way back in 1996 when I first became a transit advocate!) But, Jaffe writes, the lure of free or cheap parking is so great, especially when paired with the convenience of driving, that the benefits alone are not enough to make commuters give up driving. The better way, obviously, is to offer transit benefits but charge market rate for parking . . . Read it on CityLab.. ...
Bowen, R (27 May 2006). "Gastrointestinal Transit: How Long Does It Take?". Pathophysiology of the digestive system. Colorado ...
"Gastrointestinal Transit: How Long Does It Take?". colostate.edu. Colorado State University. Retrieved April 1, 2020. Cummings ... Transit time through the small intestine is an average of 4 hours. Half of the food residues of a meal have emptied from the ... The lower gastrointestinal tract (GI), includes the small intestine and all of the large intestine. The intestine is also ... The stomach is a major organ of the gastrointestinal tract and digestive system. It is a consistently J-shaped organ joined to ...
Rumen hypomotility, gastrointestinal stasis and anorexia develop. Also may develop tachycardia and rapid, labored respiration. ... It is also known as transit tetany, railroad disease, railroad sickness, or staggers. Early clinical signs include restlessness ...
Strid, H.; Simrén, M.; Störsrud, S.; Stotzer, PO.; Sadik, R. (June 2011). "Effect of heavy exercise on gastrointestinal transit ... "Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology ... The authors of the former paper concluded that the form of the stool is a useful surrogate measure of colon transit time. That ... The research results (see table) indicate that about 1 in 5 people have a slow transit (type 1 and 2 stools), while 1 in 12 has ...
Gastrointestinal transit time Flip-flop kinetics Alsanosi, Safaa Mohammed M.; Skiffington, Craig; Padmanabhan, Sandosh (2014 ... The gastrointestinal tract is lined with epithelial cells. Drugs must pass or permeate through these cells in order to be ... Later, esterases in the gastrointestinal tract (GIT) wall and blood hydrolyze these esters to release the parent drug. Also, ... Ions cannot passively diffuse through the gastrointestinal tract because the epithelial cell membrane is made up of a ...
Hillemeier C (November 1995). "An overview of the effects of dietary fiber on gastrointestinal transit". Pediatrics. 96 (5 Pt 2 ... Irritable bowel syndrome (IBS) is a common gastrointestinal ailment for which dietary soluble fibre is often prescribed as part ... so it has a good gastrointestinal tolerance (it has no sudden and painful release of gas, and the total gas production is much ... gradually increasing the amount over a few days allows the natural bacteria in the gastrointestinal tract to adjust to the ...
... the drug is indicated in upper gastrointestinal motility disorders and to prevent gastrointestinal symptoms associated with the ... The drug is used to relieve nausea and vomiting; to increase the transit of food through the stomach (by increasing ... Poor gastrointestinal function, nausea and vomiting is a major problem for people with Parkinson's disease because most ... There is an exception for use in people with treatment-refractory gastrointestinal symptoms under an FDA Investigational New ...
Hsu, W. H. and Lu, Z.-X. (1984). Amitraz' induced delay of gastrointestinal transit in mice: Mediated by α2 adrenergic ...
Naitoh, T; Garcia-Ruiz, A; Vladisavljevic, A; Matsuno, S; Gagner, M (Nov 2002). "Gastrointestinal transit and stress response ... Gastrointestinal Endoscopy. 72 (2): 373-80. doi:10.1016/j.gie.2010.01.066. PMID 20537637. Höglund, OV; Olsson, K; Hagman, R; ...
"Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation ... Bouras EP, Camilleri M, Burton DD, McKinzie S (May 1999). "Selective stimulation of colonic transit by the benzofuran 5HT4 ... The most frequently reported side effects are headache and gastrointestinal symptoms (abdominal pain, nausea or diarrhea). Such ...
The gastrointestinal effects of morphine are mediated primarily by μ-opioid receptors in the bowel. By inhibiting gastric ... emptying and reducing propulsive peristalsis of the intestine, morphine decreases the rate of intestinal transit. Reduction in ... In clinical settings, morphine exerts its principal pharmacological effect on the central nervous system and gastrointestinal ... colitis or other gastrointestinal afflictions related to motility, and problems with weight control in either direction In ...
May 2008). "Dose-response effect of a beta3-adrenergic receptor agonist, solabegron, on gastrointestinal transit, bowel ... Gastrointestinal and Liver Physiology. 294 (5): G1114-9. doi:10.1152/ajpgi.00051.2008. PMID 18372395. Kelleher DL, Hicks KJ, ...
Research into the prokinetic effects of probiotics on the gastrointestinal tract has also been conducted in humans. ... Bifidobacterium bifidum in combination with Lactobacillus acidophilus accelerated small intestine transit in rats. ... They are used to treat certain gastrointestinal symptoms, including abdominal discomfort, bloating, constipation, heart burn, ... Higher acetylcholine levels increase gastrointestinal peristalsis and further increase pressure on the lower esophageal ...
In a 2012 animal study, cannabichromene was shown to normalize gastrointestinal hypermotility without reducing the transit time ... Gastrointestinal Disorders.[unreliable source?] Izzo AA, Capasso R, Aviello G, Borrelli F, Romano B, Piscitelli F, Gallo L, ... Moreover, modulation of the endogenous cannabinoid system in the gastrointestinal tract may provide a useful therapeutic target ... of the gastrointestinal tract. In some cases there appears to be a genetic association. One form has been associated with ...
Due to its resistance to digestive enzymes, inulin resists absorption during its transit through the upper gastrointestinal ... Inulin's health effects had been studied in small clinical trials, which showed that it causes gastrointestinal adverse effects ...
"Gastrointestinal Transit: How Long Does It Take?". colostate.edu. Colorado State University. Retrieved April 1, 2020.. ... Further information: Gastrointestinal physiology. The lower gastrointestinal tract (GI), includes the small intestine and all ... Development of the Gastrointestinal Tract. ISBN 978-0-443-06811-9. .. *^ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso ... Transit time through the small intestine is an average of 4 hours. Half of the food residues of a meal have emptied from the ...
Symptoms include upper gastrointestinal tract dysfunction such as delayed gastric emptying or lower gastrointestinal ... dysfunction, such as constipation and prolonged stool transit time. Urinary retention, waking at night to urinate, increased ... From chewing to defecation, alpha-synuclein deposits affect every level of gastrointestinal function. ...
... reduced gastrointestinal absorption or increased gastrointestinal loss due to rapid gastrointestinal transits. Kidney causes ... Magnesium deficiency may result from gastrointestinal or kidney causes. Gastrointestinal causes include inadequate dietary ... Insufficient selenium, vitamin D or sunlight exposure, or vitamin B6.[citation needed] Gastrointestinal causes: the distal ...
January 2010). "Effects of Velusetrag (TD-5108) on gastrointestinal transit and bowel function in health and pharmacokinetics ... Velusetrag showed accelerated intestinal and colonic transit after single dosing and accelerated gastric emptying after ... and lower gastrointestinal motility disorders including chronic idiopathic constipation and irritable bowel syndrome. It is a ...
Tedman, RA; Hall, LS (1985). "The Morphology of the Gastrointestinal Tract and Food Transit Time in the Fruit Bats Pteropus ... Even though flying foxes can have a gut transit time as fast as 12 minutes, seeds can be retained in the gut for as long as 20 ...
"A Study To Investigate The Effect Of Solabegron (GW427353) On Gastrointestinal Transit In Healthy Volunteers - Full Text View ...
... becomes active during the transit of Salmonella enterica through the gastrointestinal tract of turtles". PLOS ONE. 3 (7): e2826 ... Salmonella does not detect AHL when passing through the gastrointestinal tracts of several animal species, suggesting that the ... However, SdiA does become activated when Salmonella transits through turtles colonized with Aeromonas hydrophila or mice ...
Magnetically marked pharmaceutical dosage forms to monitor gastrointestinal transit by biomagnetic measurements, Pharm. ... The magnetic capsule delivers drugs to any targeted location in the gastrointestinal tract. The way the capsule takes is ...
Non-fermentable fibers helps with satiety, maintenance of a normal intestinal transit time and gastrointestinal motility as ... Cells of the gastrointestinal tract are constantly dying and being replaced by new cells, which requires a lot of energy. The ... The gastrointestinal tract is the source of nutrient absorption, making it integral to overall health. Therefore, feeding your ... The addition of fiber at optimal levels in a diet is essential for the normal function and health of the gastrointestinal tract ...
The second possible mode of action is the material may initiate a purging response of the gastrointestinal tract by rapidly ... This substantially decreases gut transit time, causes worm expulsion and interrupts the life cycle of parasites. This, or a ... It has been proposed that for primates, there are four hypotheses relating to geophagy in alleviating gastrointestinal ... Other ruminants learn to self-medicate against gastrointestinal parasites by increasing consumption of plant secondary ...
Gastrointestinal Bleeding". In Longo, Dan L; Fauci, Anthony S; Kasper, Dennis L; Hauser, Stephen L; Jameson, J. Larry; Loscalzo ... therefore if transit time is less than 14 hours the patient will have hematochezia, and if greater than 14 hours the patient ... Causes of upper gastrointestinal bleeding that may result in melena include malignant tumors affecting the esophagus, stomach ... However, any bleeding within the upper gastrointestinal tract or the ascending colon can lead to melena. Melena may also be a ...
"Description of a dynamic in vitro model of the dog gastrointestinal tract and an evaluation of various transit times for ... TNO (gastro-) Intestinal Models ("TIM") are model systems mimicking the digestive tract. The models are dynamic computer ... The TIM systems are being used to study the behavior of oral products during transit through the stomach, the small intestine ... David, S.E., Strozyk, M.M. & Naylor, T.A. (2010). "Using TNO gastro-Intestinal Model (TIM-1) to screen potential formulations ...
... or lower gastrointestinal dysfunction (such as constipation and prolonged stool transit time). Persons with Lewy body dementia ... Problems with gastrointestinal function can affect medication absorption. Constipation can present a decade before diagnosis, ... Heart function and every level of gastrointestinal function-from chewing to defecation-can be affected, constipation being one ... From chewing to defecation, alpha-synuclein deposits affect every level of gastrointestinal function. Almost all persons with ...
... and gastrointestinal pain. Exercise immediately after consumption can exacerbate these symptoms by decreasing transit time in ... Beyer, PL; Caviar EM; McCallum RW (2005). "Fructose intake at current levels in the United States may cause gastrointestinal ... The presence of gases and organic acids in the large intestine causes gastrointestinal symptoms such as bloating, diarrhea, ... Unabsorbed fructose creates higher osmolarity in the small intestine, which draws water into the gastrointestinal tract, ...
Microbial gastrointestinal flora in a variety of animals have shown potential for the production of biofuels. Recent research ... Transit Elevated Bus. *Vactrain. *Vehicular communication systems. Pipeline. *Pneumatic transport *Automated vacuum collection ...
A 2018 study found higher instances of breast cancer, melanoma, uterine, gastrointestinal, cervical, and thyroid cancers ... gastrointestinal cancer (0.47% compared to 0.27% - a 74% increase), thyroid cancer (0.67% compared to 0.56%) and higher rates ...
... functional gastrointestinal abnormalities contributing to bowel obstruction, vomiting, and constipation may also arise. Adults ... lack of relevant assistive technology and transportation difficulties due to limited wheelchair access or public transit that ...
"Involvement of mu-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7- ...
Gastrointestinal distress[edit]. Nausea, vomiting, anorexia, diarrhoea, abdominal cramps, and constipation are common side- ... "Electrochemotherapy as an adjunct or alternative to other treatments for unresectable or in-transit melanoma". Expert Review of ... Due to immune system suppression, neutropenic enterocolitis (typhlitis) is a "life-threatening gastrointestinal complication of ... because of gastrointestinal damage. This can result in rapid weight loss, or occasionally in weight gain, if the patient eats ...
The total time necessary for the test depends on the speed of bowel motility or transit time and may vary between 1 and 3 hours ... An upper gastrointestinal series, also called an upper gastrointestinal study or contrast radiography of the upper ... whereas the barium enema is called a lower gastrointestinal series (or study).[3] In upper gastrointestinal series examinations ... M.D, Steven R. Peikin, (2014). Gastrointestinal health third edition. [S.l.]: HarperCollins e-Books. p. 29. ISBN 9780061863653. ...
"Gastrointestinal Transit: How Long Does It Take?". Pathophysiology of the digestive system. Colorado State University. ...
Feldman, Mark (2015). Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management ( ... Antimotility drugs such as loperamide and diphenoxylate reduce the symptoms of diarrhea by slowing transit time in the gut. ...
"New Insight for the Diagnosis of Gastrointestinal Acute Graft-versus-Host Disease". Mediators Inflamm. 2014: 701013. doi ... Transit Elevated Bus. *Vactrain. *Vehicular communication systems. Pipeline. *Pneumatic transport *Automated vacuum collection ...
This is often done using a mule's gastrointestinal tract or other body cavities as containers. Swallowing has been used for the ... "The Illicit Drug Transit Zone in Central America", U.S. Drug Enforcement Administration (DEA), November 9, 2005, archived from ... In Hernandez, a woman attempted to smuggle 88 balloons of cocaine in her gastrointestinal tract. She had been detained for over ...
For patients without type 2 diabetes, the gastric transit time of food is estimated to be 30-45 minutes (the time from food ... which involves signaling between the gastrointestinal tract and the nervous system. ...
The blood is then drained in the gastrointestinal tract and spleen, where it is taken up by the hepatic veins, and blood is ... was confined to blood transit in the lungs and did not extend to the entire body. ...
Konstantopoulos K, Thomas SN (2009). "Cancer cells in transit: the vascular interactions of tumor cells". Annu Rev Biomed Eng. ... CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore ...
Similar cells have been found in the gastrointestinal tract, sciatic nerve, cardiac outflow tract and spinal and sympathetic ... Doetsch F, Petreanu L, Caille I, Garcia-Verdugo JM, Alvarez-Buylla A (December 2002). "EGF converts transit-amplifying ...
Consumption of large amounts of protein, gastrointestinal bleeding e.g. from esophageal varices (blood is high in protein, ... This may relieve constipation, one of the causes of encephalopathy, and increase bowel transit.[3] ... Metronidazole, similarly, is less commonly used because prolonged use can cause nerve damage, in addition to gastrointestinal ... and increase transit of bowel content through the gut. Doses of 15-30 ml are administered three times a day; the result is ...
"Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation ... The most frequently reported side effects are headache and gastrointestinal symptoms (abdominal pain, nausea or diarrhea). Such ... The Official Journal of the European Gastrointestinal Motility Society. 13 (5): 465-472. doi:10.1046/j.1365-2982.2001.00280.x. ... "Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans". Gut. 44 (5): 682- ...
Borie F, Glaise A, Pianta E, Veyrac M, Millat B. Long-term quality-of-life assessment of gastrointestinal symptoms before and ... Impaired bolus transit across the esophagogastric junction in postfundoplication dysphagia. Am J Gastroenterol. 2005 Aug. 100(8 ...
"Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats". ... Gastrointestinal activityEdit. Inhibition of gastrointestinal activity has been observed after administration of THC or ...
... whose activists had looked after the women in the Ethiopian transit camps, left open questions, since the JDC official who had ... There are reports that often when a woman had to undergo a gastrointestinal surgery, doctors took this opportunity to sterilize ... injections of long-acting contraceptive Depo-Provera had been forced on hundreds of Ethiopian-Jewish immigrants both in transit ...
Drugs that increase the transit time of gabapentin in the small intestine can increase its oral bioavailability; when ... "The Useage of Opioids and their Adverse Effects in Gastrointestinal Practice: A Review". Middle East Journal of Digestive ...
... in the upper gastrointestinal tract[edit]. Following a meal, the stomach and upper gastrointestinal contents ... The more viscous polysaccharides extend the mouth-to-cecum transit time; guar, tragacanth and pectin being slower than wheat ... Dietary fibers can act by changing the nature of the contents of the gastrointestinal tract and by changing how other nutrients ... Dietary fibers can change the nature of the contents of the gastrointestinal tract and can change how other nutrients and ...
Fibre and bowel transit times»։ The British Journal of Nutrition 45 (1): 77-82։ January 1981։ PMID 6258626։ doi:10.1079/ ... Liu B, Ramalho M, AlObaidy M, Busireddy KK, Altun E, Kalubowila J, Semelka RC (օգոստոսի 28, 2014)։ «Gastrointestinal imaging- ... Effect of dietary fibre on stools and the transit-times, and its role in the causation of disease»։ The Lancet 2 (7792): 1408- ...
The time taken for food or other ingested objects to transit through the gastrointestinal tract varies depending on many ... Gastrointestinal tract and Digestive system.. The Wikibook Human Physiology has a page on the topic of: The gastrointestinal ... "gastrointestinal tract" at Dorland's Medical Dictionary *^ Gastrointestinal+tract at the US National Library of Medicine ... Lower gastrointestinal tractEdit. The lower gastrointestinal tract includes most of the small intestine and all of the large ...
Gastrointestinal[edit]. Multiple types of procedures have been performed with either the 'Zeus' or da Vinci robot systems, ... standard laparoscopic antireflux surgery". Journal of Gastrointestinal Surgery. 6 (1): 11-5, discussion 15-6. doi:10.1016/S1091 ... Transit Elevated Bus. *Vactrain. *Vehicular communication systems. Pipeline. *Pneumatic transport *Automated vacuum collection ...
In the developing pancreas, transcription factor ngn3'marks the populations of cells that are in transit from undifferentiated ... adrenal and salivary glands and gastrointestinal system development. Additionally to their involvement in neuronal and glial ...
... through which the motor information transit from the motor cortex to the spinal cord and the peripheral nerves). Tractography ... Upper gastrointestinal series/Small-bowel follow-through/Lower gastrointestinal series. *Cholangiography/Cholecystography ...
Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers.. Müller M1, Canfora EE2 ... Modulation of gastrointestinal transit may be one of the mechanisms underlying the beneficial health effects of dietary fibers ... Gastrointestinal transit time may be an important determinant of glucose homeostasis and metabolic health through effects on ... Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers ...
Gastrointestinal transit times, determined by scintigraphic imaging, were compared between treatments. Gastric emptying time ... ranitidine effervescent tablet absorption bioavailability bioequivalence sodium acid pyrophosphate gastrointestinal transit ... Effect of Sodium Acid Pyrophosphate on Ranitidine Bioavailability and Gastrointestinal Transit Time. ... altered gastrointestinal transit. The first study (n = 12) involved single-dose crossover comparisons of (A) 150 mg ranitidine ...
mu-Opioid receptor-knockout mice: the role of mu-opioid receptor in gastrointestinal transit.. Roy S1, Liu HC, Loh HH. ... The role of mu-opioid receptor in gastrointestinal transit was investigated using mu-opioid receptor knockout mice (MOR-KO). ... we show that neither delta nor kappa receptor agonist given supraspinally or peripherally are able to inhibit GI transit in MOR ... Our result establishes unequivocally that inhibition of GI transit by morphine is a mu-opioid receptor mediated function. In ...
The effect of the microbiota on transit largely depends on the amount and type (fermentable vs nonfermentable) of ... diet can affect GI transit through microbiota-dependent or microbiota-independent pathways, depending on the type of dietary ... Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice Gastroenterology. 2013 May;144( ... changes in microbiota composition and function can alter host functions such as gastrointestinal (GI) transit time, which in ...
SOARES, Pedro M. G. et al. Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of ... Palabras clave : Mucositis; Methotrexate; Gastric emptying; Gastrointestinal transit; Rats. · resumen en Portugués · texto en ... CONCLUSION: Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of liquids in awake ... OBJECTIVES: To evaluate the gastric emptying and gastrointestinal transit of liquids in methotrexate-induced intestinal ...
Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans (tap-oxy). The safety ... Effects of 2 Mu-opiates on Gastrointestinal Transit Drug: Tapentadol Drug: Oxycodone Drug: Placebo Phase 4 ... Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans. ... Structural or metabolic diseases/conditions that affect the gastrointestinal system, or functional gastrointestinal disorders. ...
Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation.. The ... Colonic transit time [ Time Frame: The primary outcome of Colonic Transit Time will be evaluated with abdominal x-rays on days ... Effects of 4-week Bifidobacterium-lactis HN019 Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults ... To determine if Bifidobacterium lactis HN109 improves transit time and gastrointestinal symptoms in adults with constipation. ...
Results evidenced that the simulated gastrointestinal transit caused a decrease of the polyphenols content and total ... which decreased of about four times after the simulated gastrointestinal transit. The antimicrobial activity of the extract, ... Results evidenced that the simulated gastrointestinal transit caused a decrease of the polyphenols content and total ... after Simulated Gastro-Intestinal Transit and Evaluation of in Vitro Antimicrobial Activity. Food and Nutrition Sciences, 5, 60 ...
Gastrointestinal Transit and Mucoadhesion of Colloidal Suspensions of Lycopersicon esculentum L. and Lotus tetragonolobus ... Montisci, M.J., Dembri, A., Giovannuci, G., Chacun, H., Duchene, D. and Ponchel, G (2001) Gastrointestinal Transit and ... KEYWORDS: Staphyloccus aereus, Lectin, Glucose, Gastrointestinal, Sucrose, Pathogenic JOURNAL NAME: Food and Nutrition Sciences ... Pakalai was comparatively characterized and further evaluated for interaction with gastrointestinal bacteria-Esherichia coli ...
Role of fasting gastrointestinal motility in the variability of gastrointestinal transit time assessed by hydrogen breath test. ... Role of fasting gastrointestinal motility in the variability of gastrointestinal transit time assessed by hydrogen breath test. ... Gastrointestinal motility and transit time, measured by the hydrogen breath test, were simultaneously assessed in six healthy ... These results suggest that different phases of fasting gastrointestinal motility are major determinants of the transit time ...
Tracking gastrointestinal transit of solids in aged rats as pharmacological models of chronic dysmotility. by Selleckchem , Sep ... Dysmotility in the gastrointestinal (GI) tract often leads to impaired transit of luminal contents leading to symptoms of ... Tracking gastrointestinal transit of solids in aged rats as pharmacological models of chronic dysmotility ... To determine the GI region-specific effect, transit of six metallic beads was tracked over 12 h using high resolution X-ray ...
Gastrointestinal transit time was defined as the time taken for the contrast medium to move from the crop at time 0, to the ... The resulting radiographic series gives information on gastrointestinal tract morphology with approximation of transit time by ... Gastrointestinal. Contrast studies are commonly performed to evaluate the gastrointestinal tract. With ever increasing ... There is significant variation of gastrointestinal transit time reported between avian species, and also between individuals ...
Role of small intestinal bacterial overgrowth and delayed gastrointestinal transit time in cirrhotic patients with minimal ... and lactulose breath test for oro-cecal transit time (OCTT). ... of the small intestine and delayed intestinal transit among ...
Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated ... Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated ...
bulgaricus survive gastrointestinal transit of healthy volunteers consuming yogurt. FEMS Microbiol. Lett.250:185-187. ... and transit through the gastrointestinal tract have recently been investigated (1, 6, 13, 14, 19). Apart from dairy products, ... Probiotic properties of human lactobacilli strains to be used in the gastrointestinal tract. J. Appl. Microbiol.94:449-455. ... The most common foods used as vehicles for probiotics able to enhance the transit tolerance of bacteria are dairy products. ...
In order to reach the gastrointestinal tract in sufficient numbers to exert a therapeutic effect, probiotic bacteria must ... Finally, in addition to improved gastric transit and intestinal persistence, this approach improved the clinical efficacy of ... Improving gastric transit, gastrointestinal persistence and therapeutic efficacy of the probiotic strain Bifidobacterium breve ... f Improving gastric transit, gastrointestinal persistence and therapeutic efficacy of the probiotic strain Bifidobacterium ...
Total intestinal transit time (TITT), mean colonic transit time (MCTT) and anorectal function (anal manometry, rectal ... AIM To evaluate its effect on bowel function, gut transit and anorectal function in healthy volunteers using a double-blind, ... It holds promise for patients with slow transit constipation. ... and on colonic transit. In the present study prucalopride did ... Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and anorectal function in healthy volunteers.. @ ...
The effect of chilli powder and its pungent ingredient capsaicin on gastrointestinal transit in the rat was studied. Fasted ... The effect of chilli and its pungent ingredient capsaicin on gastrointestinal transit in the rat. ... The effect of chilli and its pungent ingredient capsaicin on gastrointestinal transit in the rat. Journal of Gastroenterology ... Total gut transit as measured by the amount of radioactive marker excreted in the stools at 18 and 24 h was unaffected by the ...
You searched for: Subject gastrointestinal transit Remove constraint Subject: gastrointestinal transit Subject dietary ... gastrointestinal transit, etc ; dairy cows; cow feeding; feed grains; dietary fiber; in vitro digestibility; lactation stage; ... gastrointestinal transit, etc ; piglet feeding; organic matter; animal health; short chain fatty acids; propionic acid; wheat ... gastrointestinal transit, etc ; dairy cows; nutrient intake; cow feeding; dietary fiber; alfalfa silage; neutral detergent ...
Effect of cisapride on the gastrointestinal transit of a solid meal in normal human subjects. Gut 1987; 28: 13-16.. *CrossRef ... Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and anorectal function in healthy volunteers. ... Intestinal transit. Ondansetron, one of the earlier 5HT receptor antagonists, delays colonic transit in normal volunteers [38 ... 2 mg twice daily of tegaserod accelerated oro-caecal transit and proximal colonic emptying, though overall colonic transit was ...
You searched for: Subject gastrointestinal transit Remove constraint Subject: gastrointestinal transit Start Over ... gastrointestinal transit, etc ; bile; constipation; foods; gastrointestinal system; irritable bowel syndrome; kiwifruit; ... gastrointestinal transit, etc ; birds; gastrointestinal system; mammals; medicine; morbidity; prospective studies; radiography ... gastrointestinal transit, etc ; birds; gastrointestinal system; mammals; medicine; morbidity; prospective studies; radiography ...
Delayed Gastrointestinal Transit And Obstruction. Orally administered barium sulfate may accumulate proximal to a constricting ... To reduce the risk of delayed GI transit and obstruction, patients should maintain adequate hydration during and in the days ... stomach and duodenum to help visualize the gastrointestinal (GI) tract in patients 12 years and older. ...
Delayed Gastrointestinal Transit and Obstruction. ​Orally administered barium sulfate may accumulate proximal to a constricting ... To reduce the risk of delayed GI transit and obstruction, patients should maintain adequate hydration during and in the days ... Seek medical attention for worsening of constipation or slow gastrointestinal passage. *Seek medical attention for any delayed ... stomach and duodenum to help visualize the gastrointestinal (GI) tract in patients 12 years and older. ...
Delayed Gastrointestinal Transit and Obstruction. Orally administered barium sulfate may accumulate proximal to a constricting ... Seek medical attention for worsening of constipation or slow gastrointestinal passage [see Warnings and Precautions (5.3)]. ... To reduce the risk of delayed GI transit and obstruction, patients should maintain adequate hydration following a barium ... Under physiological conditions, barium sulfate passes through the gastrointestinal tract in an unchanged form and is absorbed ...
Gastrointestinal transit.. Groups of mice were treated i.c.v. with endomorphin-1 (12 μg) or endomorphin-2 (3 μg) 15 min before ... transit. Endomorphin-1 decreased GI transit by 46% (P , .001) and endomorphin-2 lowered GI transit by 41% (P , .001). ... Effect of endomorphin on gastrointestinal transit. Groups of mice (n ≥ 10) received saline, endomorphin-1 (12 μg, i.c.v.) or ... Morphine and other mu drugs effectively decrease gastrointestinal transit (Reisine and Pasternak, 1996). As with traditional mu ...
Assessment of the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility ... 2010) Assessment of the relationship between body weight and gastrointestinal transit times measured by use of a wireless ... Objective - To assess the relationship between body weight and gastrointestinal transit times measured by use of a wireless ... Regression analysis was used to assess the relationship between body weight and gastrointestinal transit times. Results - ...
Oral Neurotensin Increases Gastrointestinal Transit in Suckling Rats. Tomomasa, Takeshi; Itoh, Ken; Hyman, Paul E.; More ...
Soon after, the survivability of yeast was tested under in vitro conditions mimicking the human upper gastrointestinal transit ... Soon after, the survivability of yeast was tested under in vitro conditions mimicking the human upper gastrointestinal transit ... S. boulardii had suitable resistance to alcohol and gastrointestinal conditions for probiotic alcoholic beverage development. ... Saccharomyces boulardii had suitable resistance to alcohol and gastrointestinal conditions for probiotic alcoholic beverage ...
Meanwhile, DHP exhibited strong anti-diarrheal effects as well as decreased gastrointestinal motility and the secretions ... Meanwhile, DHP exhibited strong anti-diarrheal effects as well as decreased gastrointestinal motility and the secretions ... Effect of DHP on Gastrointestinal Transit Time. This test was carried out according to the method described by Kinuthia et al ... Effect of DHP on Gastrointestinal Transit. Results showed that 30 min after administration of a charcoal meal, DHP reduced the ...
Transit time. The time taken for food or other ingested objects to transit through the gastrointestinal tract varies depending ... Transit time. The time taken for food or other ingested objects to transit through the gastrointestinal tract varies depending ... Colorado State University , Gastrointestinal Transit: How Long Does It Take? Last updated on May 27, 2006. Author: R. Bowen. ... Colorado State University > Gastrointestinal Transit: How Long Does It Take? Last updated on May 27, 2006. Author: R. Bowen. ...
  • The complex relationship between dietary fiber intake, the gastrointestinal tract and host metabolism. (nih.gov)
  • Dysmotility in the gastrointestinal (GI) tract often leads to impaired transit of luminal contents leading to symptoms of diarrhea or constipation. (selleckchem.com)
  • Contrast studies are commonly performed to evaluate the gastrointestinal tract. (bmj.com)
  • The resulting radiographic series gives information on gastrointestinal tract morphology with approximation of transit time by evaluating contrast medium progression. (bmj.com)
  • Gaseous anaesthetic induction can also lead to aerophagia and gaseous dilation of the gastrointestinal tract, complicating film interpretation and potentially leading to false positive identification of proventricular dilation (McMillan 1999). (bmj.com)
  • The real-time images produced allow assessment of gastrointestinal tract morphology, and also appreciation of peristaltic movements for superior assessment of gastrointestinal motility. (bmj.com)
  • Abnormalities indicative of PDD include dilation of the gastrointestinal tract, particularly the proventriculus and proventricular-ventricular junction, and slow passage of contrast media. (bmj.com)
  • This study utilised fluoroscopy in evaluation of the intestinal tract of African Grey parrots, with subsequent comparison of the transit times recorded against reported values from radiographic contrast series. (bmj.com)
  • The ability of probiotic strains to survive passage through the gastrointestinal tract can be mainly attributed to their acid and bile tolerance. (asm.org)
  • Some strains of Lactobacillus and Bifidobacterium species can tolerate acidic stress when ingested with milk products ( 4 , 12 ), and the high fat content of cheeses protects probiotic populations during passage through the gastrointestinal tract ( 18 ). (asm.org)
  • Procedures that may enhance the viability of probiotic populations during processing, storage, and transit through the gastrointestinal tract have recently been investigated ( 1 , 6 , 13 , 14 , 19 ). (asm.org)
  • Table olives enriched with these microorganisms have been validated as a vehicle for incorporating probiotic bacterial species and delivering them into the human gastrointestinal tract ( 10 ). (asm.org)
  • In order to reach the gastrointestinal tract in sufficient numbers to exert a therapeutic effect, probiotic bacteria must resist the deleterious actions of low pH, elevated osmolarity and bile salts. (microbiologyresearch.org)
  • E-Z-HD is indicated for use in double-contrast radiographic examinations of the esophagus , stomach and duodenum to help visualize the gastrointestinal ( GI ) tract in patients 12 years and older. (rxlist.com)
  • an endoclip (pictured, right) is used to close two mucosal surfaces in the gastrointestinal tract without the need for surgery and suturing ? (thefullwiki.org)
  • self-expandable metallic stents (pictured) are prosthetic metal tubes inserted by fibre optic cameras in order to treat cancers of the gastrointestinal tract ? (thefullwiki.org)
  • hemosuccus pancreaticus , a rare cause of bleeding in the gastrointestinal tract , can cause silver -coloured stools if the bleeding source obstructs the common bile duct ? (thefullwiki.org)
  • In an adult male human, the gastrointestinal (GI) tract is approximately 5 metres (20 ft) long in a live subject, or up to 9 metres (30 ft) without the effect of muscle tone , and consists of the upper and lower GI tracts. (thefullwiki.org)
  • The lower gastrointestinal tract comprises the most of the intestines and the anus. (thefullwiki.org)
  • To simulate the gastrointestinal tract of the dog, the dynamic gastrointestinal tract model developed by Minekus et al. (atla.org.uk)
  • The overall conclusion is that the model is a useful tool for mimicking the gastrointestinal tract of dogs. (atla.org.uk)
  • Envenomation with scorpion toxin may produce a range of clinical manifestations related to the gastrointestinal tract, including salivation, epigastric pain, vomiting and diarrhea (1). (scielo.br)
  • Despite the clinical and experimental evidence that tityustoxin may influence the gastrointestinal tract and produce striking motor effects, its influence on gastrointestinal transit has not been extensively investigated. (scielo.br)
  • Therefore a trial is needed to investigate the behaviour of the SmartPill® during its passage through the human gastrointestinal tract immediately after surgery. (clinicaltrials.gov)
  • Using those values, it is possible to analyse gastric emptying, length of small bowel, large bowel or whole gut passage and the smooth muscle contractility/peristalsis of the whole gastrointestinal tract. (clinicaltrials.gov)
  • The aim of the study is to disclose the characteristics of the advance of VCE through the whole gastrointestinal tract. (biomedsearch.com)
  • This study may be the preliminary results for VCE investigating the whole gastrointestinal tract in the near future. (biomedsearch.com)
  • The luminal surface of the gastrointestinal tract is covered by a viscous mucus layer, which serves as the primary interface at which the host interacts with a dense microbial community. (nature.com)
  • HMOs are indigestible by humans and are degraded throughout the gastrointestinal tract of breast-fed infants [ 21 ], becoming the primary microbiota-accessible carbohydrates available in the newborn diet. (nature.com)
  • See also gastrointestinal tract . (wikipedia.org)
  • The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue , salivary glands , pancreas , liver , and gallbladder ). (wikipedia.org)
  • Peristalsis is the rhythmic contraction of muscles that begins in the esophagus and continues along the wall of the stomach and the rest of the gastrointestinal tract . (wikipedia.org)
  • The largest structure of the digestive system is the gastrointestinal tract (GI tract). (wikipedia.org)
  • The mouth is the first part of the upper gastrointestinal tract and is equipped with several structures that begin the first processes of digestion. (wikipedia.org)
  • In previous work, a transcriptional fusion system (i.e., luciferase genes under the control of a deregulated promoter) was used to demonstrate that a derivative of the Lactobacillus casei DN-114 001 strain, ingested in a fermented milk and thus exhibiting initially a very weak metabolic activity, synthesized proteins de novo after its transit in the digestive tract of mice harboring human microbiota (known as human-microbiota-associated mice). (asm.org)
  • Little work has been carried out on L. casei recovery in DT content and, furthermore, on its pharmacokinetics in the human gastrointestinal tract. (asm.org)
  • The gastrointestinal tract, (GI tract, GIT, digestive tract, digestion tract, alimentary canal) is the tract from the mouth to the anus which includes all the organs of the digestive system in humans and other animals. (wikipedia.org)
  • The mouth, esophagus, stomach and intestines are all part of the gastrointestinal tract. (wikipedia.org)
  • The human gastrointestinal tract consists of the esophagus, stomach, and intestines, and is divided into the upper and lower gastrointestinal tracts. (wikipedia.org)
  • However, the complete human digestive system is made up of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver and gallbladder). (wikipedia.org)
  • The gastrointestinal tract contains trillions of microbes, with some 4,000 different strains of bacteria having diverse roles in maintenance of immune health and metabolism. (wikipedia.org)
  • The lower gastrointestinal tract includes most of the small intestine and all of the large intestine. (wikipedia.org)
  • Greek: éntera) is the segment of the gastrointestinal tract extending from the pyloric sphincter of the stomach to the anus and as in other mammals, consists of two segments, the small intestine and the large intestine. (wikipedia.org)
  • Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation. (clinicaltrials.gov)
  • To determine if Bifidobacterium lactis HN109 improves transit time and gastrointestinal symptoms in adults with constipation. (clinicaltrials.gov)
  • Constipation is a commonly diagnosed gastrointestinal disorder with an estimated prevalence in the general population of 12-19%, which results in lower quality of life and significant healthcare costs to the individual. (clinicaltrials.gov)
  • Numerous studies have been published addressing the utility of probiotics for gastrointestinal health including constipation. (clinicaltrials.gov)
  • Given the promising clinical results of probiotics on gastrointestinal health to date, the objective of this clinical trial is to evaluate the safety and effectiveness of 4-week Bifidobacterium lactis HN019 supplementation, in a dose-ranging fashion, on Colonic Transit Time (CTT) and gastrointestinal symptoms in adults with constipation. (clinicaltrials.gov)
  • The aim of this research was to develop a technique using high resolution X-ray imaging to study pharmacologically induced aged rat models of chronic GI dysmotility that mimic accelerated transit (diarrhea) or constipation. (selleckchem.com)
  • How is slow-transit constipation (STC) characterized? (medscape.com)
  • Colchicine is effective for short-term treatment of slow transit constipation: a double-blind placebo-controlled clinical trial. (medscape.com)
  • Adverse GI effects were measured with the bowel function index, gastrointestinal symptom rating scale, patient assessment of constipation symptom questionnaire , and Bristol stool form scale. (bvsalud.org)
  • Accordingly, we further hypothesised that characteristics of abdominal pain in NBD are different from those of chronic idiopathic constipation (CIC) and only weakly associated with prolonged gastrointestinal transit time. (hindawi.com)
  • Gastrointestinal complications (e.g., constipation, bowel obstruction, diarrhea) can be tumor or treatment related and are common in cancer patients. (oncolink.org)
  • This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the pathophysiology and treatment of gastrointestinal complications, including constipation, impaction, bowel obstruction, diarrhea, and radiation enteritis. (oncolink.org)
  • It may show a delay in transit time in persons with constipation, or the results may be normal in patients with IBS. (medscape.com)
  • However, occasional constipation and/or diarrhea can be a burdensome gastrointestinal issue that occurs in many individuals and whose treatment remains challenging. (omicsonline.org)
  • Unfortunately, digestive symptoms such as diarrhea, vomiting, constipation or bladder infections may be the first sign of a number of gastrointestinal conditions that require medical attention before they become unmanageable. (cerebralpalsy.org)
  • A study published July 1, 1999 by Elsevier titled "Gastrointestinal manifestations in children with Cerebral Palsy" found the majority (92%) of those with Cerebral Palsy had one or more significant gastrointestinal symptoms, including difficulty swallowing, regurgitation, abdominal pain, chronic pulmonary aspiration, and chronic constipation. (cerebralpalsy.org)
  • Gastric emptying time was unchanged, but small intestinal transit time was decreased to 56% in the presence of SAPP. (springer.com)
  • The intestinal transit time was 120 minutes for both bead types. (ismrm.org)
  • Gastric meal delivery and the effects of intestinal transit time on protein digestibility and availability for absorption of calcium from dog food were studied to evaluate the model. (atla.org.uk)
  • Overall, short-term probiotic supplementation decreases intestinal transit time with consistently greater treatment effects identified in constipated or older adults and with certain probiotic strains. (greenmedinfo.com)
  • Scintigraphic study of intestinal transit time, accomplished by oral administration of radiolabeled foods, allows study of gastric emptying and intestinal progression of the meal. (medscape.com)
  • The Bristol stool scale is also very sensitive to changes in intestinal transit time caused by medications, such as antidiarrhoeal loperamide , senna , or anthraquinone with laxative effect. (wikipedia.org)
  • We here investigated whether allogenic FMT using faeces from post-Roux-en-Y gastric bypass donors (RYGB-D) compared with using faeces from metabolic syndrome donors (METS-D) has short-term effects on glucose metabolism, intestinal transit time and adipose tissue inflammation in treatment-naïve, obese, insulin-resistant male subjects. (bmj.com)
  • Secondary outcome parameters were changes in resting energy expenditure, intestinal transit time, faecal short-chain fatty acids (SCFA) and bile acids, and inflammatory markers in subcutaneous adipose tissue related to intestinal microbiota composition. (bmj.com)
  • Moreover, a trend (p=0.052) towards faster intestinal transit time following RYGB-D FMT was seen. (bmj.com)
  • Ali, BH & Bashir, AA 1993, ' The effect of some α2-adrenoceptor agonists and antagonists on gastrointestinal transit in mice: Influence of morphine, castor oil and glucose ', Clinical and Experimental Pharmacology and Physiology , vol. 20, no. 1, pp. 1-6. (elsevier.com)
  • Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers. (nih.gov)
  • Gastrointestinal transit time may be an important determinant of glucose homeostasis and metabolic health through effects on nutrient absorption and microbial composition, among other mechanisms. (nih.gov)
  • Insoluble fibers are most effective in increasing colonic transit time thereby possibly affecting microbiota composition, and vice versa microbial metabolites may stimulate colonic motility. (nih.gov)
  • In addition to the direct influence that diet exerts on microbes, changes in microbiota composition and function can alter host functions such as gastrointestinal (GI) transit time, which in turn can further affect the microbiota. (nih.gov)
  • Role of fasting gastrointestinal motility in the variability of gastrointestinal transit time assessed by hydrogen breath test. (bmj.com)
  • Gastrointestinal motility and transit time, measured by the hydrogen breath test, were simultaneously assessed in six healthy volunteers. (bmj.com)
  • The lactulose transit time decreased significantly from a peak with phase I through phase II to a minimum with phase III (mean (SD) 155 (26) min v 120 (10) min v 94 (14) min, p less than 0.001). (bmj.com)
  • These results suggest that different phases of fasting gastrointestinal motility are major determinants of the transit time estimated by the hydrogen breath test and explain the variability of this test in practice. (bmj.com)
  • There is significant variation of gastrointestinal transit time reported between avian species, and also between individuals with factors such as diet, food availability, health, stress, medications administered and age cited as factors (Garcia Martinez and others 2007). (bmj.com)
  • All patients underwent a glucose breath test for small intestinal bacterial overgrowth (SIBO) and lactulose breath test for oro-cecal transit time (OCTT). (nih.gov)
  • Results - Gastric emptying time (GET) ranged from 405 to 897 minutes, small bowel transit time (SBTT) ranged from 96 to 224 minutes, large bowel transit time (LBTT) ranged from 427 to 2,573 minutes, and total transit time (TTT) ranged from 1,294 to 3,443 minutes. (edu.au)
  • Bowel transit time refers to how long it takes for the food to move from the mouth to the end of the intestine (anus). (medlineplus.gov)
  • This article talks about the medical test used to determine bowel transit time using a radiopaque marker testing. (medlineplus.gov)
  • The bowel transit time varies, even in the same person. (medlineplus.gov)
  • The average transit time through the colon in someone who is not constipated is 30 to 40 hours. (medlineplus.gov)
  • Up to a maximum of 72 hours is still considered normal, although transit time in women may reach up to around 100 hours. (medlineplus.gov)
  • The bowel transit time test is rarely done these days. (medlineplus.gov)
  • Oxycodone increased median total GI transit time from 22.2 to 43.9 hours (P cecum and ascending colon from 5.7 to 9.9 hours (P = 0.012), rectosigmoid colon transit from 2.7 to 9.0 hours (P = 0.044), and colorectal transit time from 18.6 to 38.6 hours (P = 0.001). (bvsalud.org)
  • 1 ] The longer the transit time of stool in the large intestine, the greater the fluid absorption and the drier and harder the stool becomes. (cancer.gov)
  • gastrointestinal transit time. (cdc.gov)
  • Brief physical inactivity prolongs colonic transit time in elderly active men. (biomedsearch.com)
  • The effects of two weeks of reduced activity on gastrointestinal transit time were studied in nine healthy elderly subjects, who had engaged in regular recreational exercise for ten years. (biomedsearch.com)
  • Mouth-to-cecum transit time was measured by a breath hydrogen method and mean total and segmental colonic transit times by a radiopaque marker method. (biomedsearch.com)
  • The mouth-to-cecum transit time did not change during the period of physical inactivity. (biomedsearch.com)
  • The transit time of the rectosigmoid segment of the colon was not affected. (biomedsearch.com)
  • In conclusion, the period of physical inactivity prolonged the colonic transit time in active elderly subjects. (biomedsearch.com)
  • Foster, David J.R. / Population In Vitro-In Vivo Correlation Model Linking Gastrointestinal Transit Time, pH, and Pharmacokinetics : Itraconazole as a Model Drug . (edu.au)
  • The model is computer-controlled to simulate physiological parameters such as pH, transit time and secretion of digestive juices, as derived from the literature. (atla.org.uk)
  • The digestibility of protein and the availability of calcium for absorption increased with a longer transit time. (atla.org.uk)
  • Parameters such as pH, transit time and enzyme activity can be mimicked and can be kept within a physiological range. (atla.org.uk)
  • Mean between-subject coefficients of variation for gastric emptying time (GET), small and large bowel transit time (SLBTT), and total transit time (TTT) were 26.9%, 32.3%, and 19.6%, respectively. (midasnetwork.us)
  • Mouth-to-caecum transit time was not altered, but whole-gut transit time was prolonged. (meta.org)
  • normalization of colon transit time and an increase in the tone of the IAS seem to be the main determinants of efficacy. (meta.org)
  • Whole gut transit time and gas excretion in breath and flatus were not different during the periods of ispaghula and placebo ingestion. (nih.gov)
  • Therefore the SmartPill® would be an ideal, patient and investigator independent tool to investigate gastrointestinal function and transit time after visceral surgery. (clinicaltrials.gov)
  • The aims of the present study were threefold: to describe the characteristics of abdominal pain in patients with SCI, to compare the characteristics of colorectal function and abdominal pain in patients with SCI and patients with CIC, and, finally, to investigate the association between abdominal pain and gastrointestinal transit time in patients with SCI. (hindawi.com)
  • Probiotics may improve whole gut transit time, stool frequency, and stool consistency. (greenmedinfo.com)
  • Although defecography offers some information about the kinetics of rectal emptying, scintigraphic study of the small bowel or colonic transit time is currently preferred. (medscape.com)
  • In-patient' and 'gastric transit time' were detected by statistical analysis as significant factors affecting VCE's transit to the cecum. (biomedsearch.com)
  • This article discusses the medical test used to determine bowel transit time. (northside.com)
  • Your diet affects the bowel transit time. (northside.com)
  • For example, if you eat a lot of foods rich in fiber (whole grains, vegetables, and fruits), you will have a more rapid transit time and a heavier, bulkier stool. (northside.com)
  • If the transit time is 72 hours or more, you may have slowed bowel function. (northside.com)
  • male gender and higher small-bowel transit time are predictive factors for an inadequate cleanliness. (isciii.es)
  • More rapid small intestinal transit associated with an excipient of a solution dosage form apparently resulted in a decreased extent of ranitidine absorption. (springer.com)
  • Influence of gastrointestinal anatomic site of drug delivery on the absorption characteristics of ranitidine. (springer.com)
  • It is therefore conceivable that any alteration of the gastrointestinal motility can affect the rate of absorption of fluoride and leads to aggravation of its toxic effects. (fluoridealert.org)
  • A digesta transit model was used to describe meal transit and a single compartment model used to predict percentage absorption from the plasma TRL response. (uea.ac.uk)
  • Increased lutein absorption correlated to slower gastrointestinal (GI) transit for the whole-leaf meal. (uea.ac.uk)
  • Purpose: To establish an in vitro-in vivo correlation (IVIVC) model for Sporanox and SUBA-itraconazole formulations and to understand the impact of gastrointestinal (GI) pH and transit times on itraconazole dissolution and absorption. (edu.au)
  • The in vivo pharmacokinetics of itraconazole was described with a 2-compartment model with 4-transit absorption compartments. (edu.au)
  • however, the area under the curve remained the same.CONCLUSION: The prolonged GI transit after glepaglutide treatment, along with demonstrated positive effects on intestinal mucosal growth and potential effects on GI hypersecretions, is believed to contribute to the observed beneficial effects on fecal output (primary endpoint) and associated improvement in intestinal absorption. (regionh.dk)
  • Opioids prolong gastrointestinal transit times, possibly causing delayed and prolonged absorption. (medscape.com)
  • We report a novel high-resolution, non-invasive, X-ray imaging technique that provides new insights into GI transit rates in live rats. (selleckchem.com)
  • The results demonstrate that loperamide slowed overall transit in aged rats, while prucalopride increased stomach emptying and accelerates colonic transit. (selleckchem.com)
  • We evaluated the effects of vincristine on the gastrointestinal (GI) motility of awake rats and correlated them with the course of vincristine -induced peripheral neuropathy . (bvsalud.org)
  • The effects of a fraction (T1) of Tityus serrulatus scorpion venom prepared by gel filtration on gastric emptying and small intestinal transit were investigated in male Wistar rats. (scielo.br)
  • Inhibition of both gastric emptying and intestinal transit in rats injected with scorpion toxin suggests an increased resistance to aboral flow, which might be caused by abnormal neurotransmitter release or by the local effects of venom on smooth muscle cells. (scielo.br)
  • In the present study, we show that injection of a partially purified fraction from T. serrulatus venom in anesthetized rats is followed by a remarkable inhibition not only of gastric emptying but also of small intestinal transit. (scielo.br)
  • With the exception of an experiment carried out to determine the pattern of intestinal transit in awake rats, all other studies were performed on animals anesthetized with an intraperitoneal injection of urethane (1.5 g/kg). (scielo.br)
  • Gastric emptying and intestinal transit times were measured in 7 healthy volunteers who consumed 2 different types of alginate beads (weakly and strongly gelled). (ismrm.org)
  • The effects of fluoride on gastric emptying and intestinal transit were studied in the mouse using a carboxymethyl cellulose (CMC) solution as a non-nutrient meal. (fluoridealert.org)
  • In recent years, probiotics have been commonly used to alleviate symptoms in a variety of gastrointestinal disorders. (clinicaltrials.gov)
  • To employ an experimental model of opioid-induced bowel dysfunction in healthy human volunteers , and evaluate the impact of opioid treatment compared to placebo on gastrointestinal (GI) symptoms and motility assessed by questionnaires and regional GI transit times using the 3-dimensional (3D)-Transit system. (bvsalud.org)
  • The patient with a fecal impaction may present with circulatory, cardiac, or respiratory symptoms rather than with gastrointestinal symptoms. (cancer.gov)
  • A barium meal is a helpful study in the diagnosis of intestinal motility disorders, but it should never be administered to patients with symptoms of pseudo-obstruction, because it may cause irreversible blockage of intestinal transit. (medscape.com)
  • In pediatric settings, parents often raise concerns about possible gastrointestinal (GI) symptoms in autism spectrum disorder (ASD), yet the specificity of these concerns are not well studied. (aappublications.org)
  • In addition to intestinal survival, an active metabolism for transiting bacteria is certainly an important feature which may act on parameters, leading to beneficial effects. (asm.org)
  • Dr. Lacy is the author of over 165 peer-reviewed articles on gastrointestinal motility disorders and functional bowel disorders, has written and/or edited 6 books on gastrointestinal motility disorders and functional bowel disorders, and has written multiple text book chapters. (mayoclinic.org)
  • This study assesses the most likely level of impaired bolus transit when abnormalities are noted by impedance which can help to further characterize esophageal motility disorders. (sages.org)
  • These results have implications for disorders that affect GI transit and gut microbial communities, including irritable bowel syndrome and inflammatory bowel disease. (nih.gov)
  • Park SY, Burton D, Busciglio I, Eckert D, Camilleri M. Regional colonic transit pattern does not conclusively identify evacuation disorders in constipated patients with delayed colonic transit. (medscape.com)
  • Camilleri M. Disorders of gastrointestinal motility. (medlineplus.gov)
  • This volume provides a comprehensive and up-to-date theoretical review and practical guide on pediatric gastrointestinal motility and functional disorders. (springer.com)
  • Written by world-renown experts in the field, Pediatric Neurogastroenterology: Gastrointestinal Motility and Functional Disorders in Children, Second Edition is a valuable resource for pediatric gastroenterologists, adult gastroenterologists, pediatricians, and all professionals involved in the treatment and management of children with such disorders. (springer.com)
  • This is a comprehensive and up-to-date review as well as practical guide to the diagnosis and treatment of pediatric gastrointestinal motility and functional disorders. (springer.com)
  • Dr. Brian E. Lacy is a board certified gastroenterologist who focuses his research and clinical interests on disorders of gastrointestinal motility. (mayoclinic.org)
  • Loperamide (1 mg/kg) slowed stomach emptying and GI transit at 9 and 12 h. (selleckchem.com)
  • In this study, most ingested L. casei cells transited from the stomach to the duodenum-jejunum within 1 h postingestion. (asm.org)
  • Gastrointestinal is an adjective meaning of or pertaining to the stomach and intestines. (wikipedia.org)
  • Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: update 2018. (medscape.com)
  • Have a history of organic diseases, structural or biochemical, of the gastrointestinal system that can cause dyspepsia. (knowcancer.com)
  • The IVIVC model provides more insight into the observed variability of itraconazole pharmacokinetics and indicated that GI pH and transit times influence in vivo dissolution and exposure. (edu.au)
  • ABSTRACT: Lectin purified from wild underutilized local bean-Otili, Feregede, Pakalai was comparatively characterized and further evaluated for interaction with gastrointestinal bacteria-Esherichia coli and Staphylococcus aureus. (scirp.org)
  • To exert their beneficial effect after human consumption, probiotic bacteria need to survive first the manufacturing process of the carrier food and then the gastrointestinal ecosystem. (asm.org)
  • The most common foods used as vehicles for probiotics able to enhance the transit tolerance of bacteria are dairy products. (asm.org)
  • At later times, the bulk of bacteria had transited to the ileum and the cecum. (asm.org)
  • It is well accepted that probiotic bacteria should remain alive during intestinal transit to exert beneficial effects on the host ( 10 , 12 ), although one should not exclude the possibility that cell fragments or components may also exert physiological benefits especially related to potential immunomodulation ( 22 , 23 ). (asm.org)
  • abstract = "BACKGROUND: Patients with short bowel syndrome (SBS) and distal-bowel resections lack neuroendocrine feedback regulations, potentially resulting in rapid gastrointestinal (GI) transit. (regionh.dk)
  • a high GC implies faster colonic transit, a GC of 1 implies all isotope is in the ascending colon, and a GC of 5 implies all isotope is in the stool. (clinicaltrials.gov)
  • Regional GI transit times were determined using the 3D-Transit system, and segmental transit times in the colon were determined using a custom Matlab® graphical user interface. (bvsalud.org)
  • This prolongation was due to slowed transit through the right and the left segments of the colon. (biomedsearch.com)
  • One day after completing the vincristine treatment , the animals were fasted for 24 h, gavage-fed with a test meal and sacrificed 10 min later to measure gastric emptying (GE), GI transit and colon weight. (bvsalud.org)
  • 4. After sedation, upper gastrointestinal endoscopy and flexible sigmoidoscopy to obtain 6 mucosal biopsies from the small bowel and sigmoid colon for immunohistochemical analysis. (bioportfolio.com)
  • Dogs with the lowest body weight of the cohort appeared to have longer gastric and small intestinal transit times than did large- and giantbreed dogs. (edu.au)
  • Our result establishes unequivocally that inhibition of GI transit by morphine is a mu-opioid receptor mediated function. (nih.gov)
  • 3. Morphine (2, 4 and 8 mg/kg) significantly inhibited gastrointestinal transit. (elsevier.com)
  • However we are now entering an exciting era, as many new 5HT modulating drugs are becoming available for treating functional gastrointestinal (GI) disease. (wiley.com)
  • In addition, it was reported to be associated with significantly fewer treatment discontinuations due to a significantly lower incidence of gastrointestinal-related adverse events compared with equivalent doses of oxycodone. (clinicaltrials.gov)
  • Prucalopride (4 mg/kg) did not significantly alter GI transit scores, but at a dose of 4 mg/kg beads had moved significantly more distal than the caecum in 12 h compared to controls. (selleckchem.com)
  • Atropine treatment significantly depressed intestinal transit from 56.5% to 37.7% in the absence of NaF and from 70.1% to 42.8% in its presence. (fluoridealert.org)
  • Chronic vincristine treatments with total cumulative doses of at least 250 µg/kg significantly decreased GE by 31-59 percent and GI transit by 55-93 percent. (bvsalud.org)
  • The WMC transit did not significantly change in any of the dose groups. (regionh.dk)
  • The anchorage of bacterial strains to artichokes improved their survival in simulated gastrointestinal digestion. (asm.org)
  • Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and anorectal function in healthy volunteers. (semanticscholar.org)
  • AIM To evaluate its effect on bowel function, gut transit and anorectal function in healthy volunteers using a double-blind, placebo-controlled crossover study. (semanticscholar.org)
  • Get detailed information about gastrointestinal complications and ways to manage them in this clinician summary. (oncolink.org)
  • Conclusions and Clinical Relevance - A positive relationship did not exist between body weight and gastrointestinal transit times. (edu.au)
  • is it possible to correlate the measured parameters (delayed gastrointestinal transit, lack of peristalsis) with the clinical signs of POI (nausea, vomiting, prolonged duration until first postoperative defecation). (clinicaltrials.gov)
  • The 5-hydroxytryptamine type 4 (5-HT4 ) receptor agonist prucalopride was used to accelerate transit, and the opioid agonist loperamide was used to delay transit. (selleckchem.com)
  • Studies have suggested that L. casei DN-114 001 reduces acute diarrhea in healthy children ( 19 , 20 ), modulates ex vivo the production of proinflammatory cytokines in Crohn's disease ( 4 ) and enhances the immune system during its transit in the DT ( 18 , 21 ). (asm.org)
  • Gastrointestinal transit times, determined by scintigraphic imaging, were compared between treatments. (springer.com)
  • 8 m g/ml), which decreased of about four times after the simulated gastrointestinal transit. (scirp.org)
  • Currently, assessment of transit times relies on comparison with anecdotal values or published values recorded from radiographic series in anaesthetised birds which may not be directly comparable. (bmj.com)
  • OBJECTIVES: To quantify changes in gastric and intestinal emptying times in the conscious dog following gastrointestinal acupoint stimulation. (usda.gov)
  • Objective - To assess the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility capsule (WMC) system in healthy dogs. (edu.au)
  • Regression analysis was used to assess the relationship between body weight and gastrointestinal transit times. (edu.au)
  • There was no positive relationship between body weight and gastrointestinal transit times. (edu.au)
  • No associations between questionnaire scores and segmental transit times were detected. (bvsalud.org)
  • Self -assessed GI adverse effects and increased GI transit times in different segments were induced during oxycodone treatment . (bvsalud.org)
  • Methods: IVIVC was developed based on fed/fasted pharmacokinetic data from randomized cross-over trials, in vitro dissolution studies, and prior information about typical and between subject variability of GI pH and transit times. (edu.au)
  • Pharmacokinetic profiles for fasted itraconazole periods were described based on the in vitro dissolution model, in vivo disposition model, and the prior information on GI pH and transit times. (edu.au)
  • A significant difference was found between medium and slow transit times for the nitrogen content in the ileal delivery effluent and the jejunal dialysates (p (atla.org.uk)
  • Assessment of the variation associated with repeated measurement of gastrointestinal transit times and assessment of the effect of oral ranitidine on gastrointestinal transit times using a wireless motility capsule system in dogs. (midasnetwork.us)
  • This study aimed to evaluate the variation associated with repeated measurement of gastrointestinal (GI) transit times and the effect of oral ranitidine on GI transit times in healthy dogs using a wireless motility capsule (WMC) system. (midasnetwork.us)
  • For the 4th repetition, each dog was given ranitidine hydrochloride (75 mg PO every 12 hours) prior to and during assessment of GI transit times. (midasnetwork.us)
  • No significant differences in GI transit times were found between any of the 4 repetitions. (midasnetwork.us)
  • Under these experimental conditions, no significant effects of oral ranitidine on GI transit times were observed. (midasnetwork.us)
  • Total gastrointestinal transit times (GITT) were measured by radiopaque markers. (hindawi.com)
  • average gastric and small bowel transit times were 48.0 and 291.7 minutes. (biomedsearch.com)
  • Your doctor may ask you to record transit times as you introduce fiber into your diet. (northside.com)
  • A solid dosage form designed to facilitate rapid and reliable oral, esophageal and GI transit has a surface area of the contact patch, i.e., the area of contact between the dosage form and the bodily surface reduced. (freepatentsonline.com)
  • 4. The acute administration of glucose (5.04 g/kg i.p.) potentiated the inhibition of gastrointestinal transit produced by clonidine (1 mg/kg) and BHT-920 (40 mg/kg). (elsevier.com)
  • Soon after, the survivability of yeast was tested under in vitro conditions mimicking the human upper gastrointestinal transit. (frontiersin.org)
  • This differentiates the embryonic borders between the foregut and midgut, and is also the division commonly used by clinicians to describe gastrointestinal bleeding as being of either "upper" or "lower" origin. (wikipedia.org)
  • Modulation of gastrointestinal transit may be one of the mechanisms underlying the beneficial health effects of dietary fibers. (nih.gov)
  • Subsequently, we briefly address the reported health effects of different dietary fibers and discuss to what extent the fiber-induced health benefits may be mediated through modulation of gastrointestinal transit. (nih.gov)
  • Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated using pharmacokinetic models describing plasma concentrations of drugs from various enteric-coated pellet formulations. (oregonstate.edu)
  • Meanwhile, DHP exhibited strong anti-diarrheal effects as well as decreased gastrointestinal motility and the secretions induced by Sennae and castor oil in a dose-dependent manner. (frontiersin.org)
  • 1. The effects of graded doses of the α 2 -adrenoceptor agonists clonidine, tizanidine and BHT-920, and the α 2 -adrenoceptor antagonists yohimbine and idazoxan, on gastrointestinal transit were investigated in mice using the charcoal meal test. (elsevier.com)
  • mu-Opioid receptor-knockout mice: the role of mu-opioid receptor in gastrointestinal transit. (nih.gov)
  • The role of mu-opioid receptor in gastrointestinal transit was investigated using mu-opioid receptor knockout mice (MOR-KO). (nih.gov)
  • Analysis of gut motility revealed that humanized mice fed a standard polysaccharide-rich diet had faster GI transit and increased colonic contractility compared with GF mice. (nih.gov)
  • Humanized mice with faster transit due to administration of polyethylene glycol or a nonfermentable cellulose-based diet had similar changes in gut microbiota composition, indicating that diet can modify GI transit, which then affects the composition of the microbial community. (nih.gov)
  • However, altered transit in mice fed a diet of fermentable fructooligosaccharide indicates that diet can change gut microbial function, which can affect GI transit. (nih.gov)
  • Based on studies in humanized mice, diet can affect GI transit through microbiota-dependent or microbiota-independent pathways, depending on the type of dietary change. (nih.gov)
  • MSG after chronic or acute supplementation had no effect on food intake, body weight, adipose tissue masses, gastric emptying rate, incorporation of dietary nitrogen in gastrointestinal and other tissues, and protein synthesis in intestinal mucosa, liver and muscles. (bioscience.org)
  • MII allows the assessment of bolus transit. (sages.org)