Gastrointestinal Transit
Ileus
A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.
Croton Oil
Castor Oil
Digestive System Physiological Phenomena
Zanthoxylum
A plant genus of the family RUTACEAE. Some members of Zanthoxylum are reclassified from ELEUTHEROCOCCUS, Melicope, and EVODIA. The twigs are used as dental brushing sticks (TOOTHBRUSHING). Most plants that are called Fagara have been reclassified as Zanthoxylum, however some Fagara were reclassified to MELICOPE (also in the Rutacea family) or to GLEDITSIA (a genus in the FABACEAE family).
Medicine, East Asian Traditional
Loperamide
Constipation
Nalbuphine
Antidiarrheals
Gastrointestinal Agents
Medetomidine
Colon
Receptors, Serotonin, 5-HT4
Intestine, Small
Gastrointestinal Tract
Ginger
Pentazocine
Peristalsis
Morphine
Cisapride
Analgesics, Opioid
Yohimbine
Feces
Clonidine
Ileum
Dietary Fiber
Dose-Response Relationship, Drug
Digestive System
Delayed-Action Preparations
Diarrhea
Stomach
Intestines
Probiotics
Live microbial DIETARY SUPPLEMENTS which beneficially affect the host animal by improving its intestinal microbial balance. Antibiotics and other related compounds are not included in this definition. In humans, lactobacilli are commonly used as probiotics, either as single species or in mixed culture with other bacteria. Other genera that have been used are bifidobacteria and streptococci. (J. Nutr. 1995;125:1401-12)
Biological Availability
Drug Interactions
Cross-Over Studies
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Muscle, Smooth
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Muscle Contraction
Rats, Wistar
Segmental colonic transit after oral 67Ga-citrate in healthy subjects and those with chronic idiopathic constipation. (1/712)
Measurement of segmental colonic transit is important in the assessment of patients with severe constipation. 111In-diethylenetriamine pentaacetic acid (DTPA) has been established as the tracer of choice for these studies, but it is expensive and not readily available. 67Ga-citrate is an inexpensive tracer and when given orally is not absorbed from the bowel. It was compared with 111In-DTPA in colonic transit studies in nonconstipated control subjects and then in patients with idiopathic constipation. METHODS: Studies were performed after oral administration of 3 MBq (81 microCi) 67Ga-citrate or 4 MBq (108 microCi) 111In-DTPA in solution. Serial abdominal images were performed up to 96 h postinjection, and computer data were generated from geometric mean images of segmental retention of tracer, mean activity profiles and a colonic tracer half-clearance time. RESULTS: There were no differences in segmental retention of either tracer or in mean activity profiles between control subjects and constipated patients. Results in constipated subjects were significantly different from those in controls. The mean half-clearance times of tracer for control subjects were 28.8 h for 67Ga-citrate and 29.9 h for 111In-DTPA in control subjects and 75.0 h for 67Ga-citrate and 70.8 h for 111In-DTPA in constipated patients. CONCLUSION: Oral 67Ga-citrate can be used as a safe alternative to 111In-DTPA for accurate measurement of segmental colonic transit. (+info)Antinociceptive properties of the new alkaloid, cis-8, 10-di-N-propyllobelidiol hydrochloride dihydrate isolated from Siphocampylus verticillatus: evidence for the mechanism of action. (2/712)
The antinociceptive action of the alkaloid cis-8, 10-di-n-propyllobelidiol hydrochloride dehydrate (DPHD), isolated from Siphocampylus verticillatus, given i.p., p.o., i.t., or i.c.v., was assessed in chemical and thermal models of nociception in mice, such as acetic acid-induced abdominal constriction, formalin- and capsaicin-induced licking, and hot-plate and tail-flick tests. DPHD given by i.p., p.o., i.t., or i.c.v. elicited significant and dose-related antinociception. At the ID50 level, DPHD was about 2- to 39-fold more potent than aspirin and dipyrone, but it was about 14- to 119-fold less potent than morphine. Its analgesic action was reversed by treatment of animals with p-chlorophenylalanine, naloxone, cyprodime, naltrindole, nor-binaltrorphimine, L-arginine, or pertussis toxin. Its action was also modulated by adrenal-gland hormones but was not affected by gamma-aminobutyric acid type A or type B antagonist, bicuculine, or phaclofen, nor was it affected by glibenclamide. DPHD, given daily for up to 7 days, did not develop tolerance to itself nor did it induce cross-tolerance to morphine. However, animals rendered tolerant to morphine presented cross-tolerance to DPHD. The antinociception of DPHD was not secondary to its anti-inflammatory effect, nor was it associated with nonspecific effects such as muscle relaxation or sedation. DPHD, in contrast to morphine, did not decrease charcoal meal transit in mice, nor did it inhibit electrical field stimulation of the guinea pig ileum or mouse vas deferens in vitro. Thus, DPHD produces dose-dependent and pronounced systemic, spinal, and supraspinal antinociception in mice, including against the neurogenic nociception induced by formalin and capsaicin. Its antinociceptive effect involves multiple mechanisms of action, namely interaction with mu, delta, or kappa opioid systems, L-arginine-nitric oxide and serotonin pathways, activation of Gi protein sensitive to pertussis toxin, and modulation by endogenous glucocorticoids. (+info)Prolonged large bowel transit increases serum deoxycholic acid: a risk factor for octreotide induced gallstones. (3/712)
BACKGROUND: Treatment of acromegaly with octreotide increases the proportion of deoxycholic acid in, and the cholesterol saturation of, bile and induces the formation of gallstones. Prolongation of intestinal transit has been proposed as the mechanism for the increase in the proportion of deoxycholic acid in bile. AIMS: To study the effects of octreotide on intestinal transit in acromegalic patients during octreotide treatment, and to examine the relation between intestinal transit and bile acid composition in fasting serum. METHODS: Mouth to caecum and large bowel transit times, and the proportion of deoxycholic acid in fasting serum were measured in non-acromegalic controls, acromegalic patients untreated with octreotide, acromegalics on long term octreotide, and patients with simple constipation. Intestinal transit and the proportion of deoxycholic acid were compared in acromegalic patients before and during octreotide. RESULTS: Acromegalics untreated with octreotide had longer mouth to caecum and large bowel transit times than controls. Intestinal transit was further prolonged by chronic octreotide treatment. There were significant linear relations between large bowel transit time and the proportion of deoxycholic acid in the total, conjugated, and unconjugated fractions of fasting serum. CONCLUSIONS: These data support the hypothesis that, by prolonging large bowel transit, octreotide increases the proportion of deoxycholic acid in fasting serum (and, by implication, in bile) and thereby the risk of gallstone formation. (+info)Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. (4/712)
BACKGROUND: Prucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans, with gastrointestinal prokinetic activities in vitro. AIMS: To evaluate the effects of prucalopride on gastrointestinal and colonic transit. METHODS: A validated scintigraphic technique was used to measure gastrointestinal and colonic transit over 48 hours in 50 healthy volunteers. For seven days, each subject received a daily dose of 0. 5, 1, 2, or 4 mg prucalopride, or placebo in a double blind, randomised fashion. The transit test was performed over the last 48 hours. RESULTS: There were significant accelerations of overall colonic transit at 4, 8, 24, and 48 hours (p<0.05) and proximal colonic emptying t1/2 (p<0.05). The 0.5, 2, and 4 mg doses of prucalopride were almost equally effective and accelerated colonic transit compared with placebo. Prucalopride did not significantly alter gastric emptying (p>0.5) or small bowel transit (overall p=0. 12). The medication appeared to be well tolerated during the seven day treatment of healthy subjects. CONCLUSION: Prucalopride accelerates colonic transit, partly by stimulating proximal colonic emptying, but does not alter gastric or small bowel transit in healthy human subjects. Prucalopride deserves further study in patients with constipation. (+info)Gastric emptying and intestinal transit of pancreatic enzyme supplements in cystic fibrosis. (5/712)
OBJECTIVE: To investigate gastric emptying and intestinal transit of pelleted pancreatin in relation to food boluses. METHODS: Dual isotope scintigraphy combined with breath hydrogen sampling was used to track the concurrent gastric emptying and intestinal transit of 111indium labelled microspheres and a 99mtechnetium labelled tin colloid test meal. Twelve pancreatic insufficient cystic fibrosis patients aged 5 to 38 years performed the study. RESULTS: 50% gastric emptying times showed patient to patient variation. The mean discrepancy in 50% gastric emptying times between the two labels was > 67 minutes. Mean small bowel transit time for the food bolus was prolonged at 3.6 minutes. A significant correlation was seen between weight standard deviation score and 50% emptying time for pancreatin (r = +0.73). CONCLUSION: Gastric mixing of food and pancreatin may be limited by rapid emptying of microspheres. Patients with high dosage requirements could benefit from changing the pattern of their pancreatin supplementation. (+info)Randomised controlled trial of trophic feeding and gut motility. (6/712)
OBJECTIVES: To determine the effect of trophic feeding on gastric emptying and whole gut transit time in sick preterm infants. METHODS: A randomised, controlled, prospective study of 70 infants weighing less than 1750 g at birth, who were receiving ventilatory support, was performed. Group TF (33 infants) received trophic feeding from day 3 (0.5 ml/h if birthweight less than 1 kg, 1 ml/h if greater or equal to 1 kg) in addition to parenteral nutrition until ventilatory support finished. Group C (37 infants) received parenteral nutrition alone until ventilatory support finished. Expressed breast milk or a preterm formula were given according to maternal preference. Gastric emptying was assessed within 24 hours of nutritive milk feeding equal to 90 ml/kg/day, using ultrasound scans to measure the reduction in the gastric antral cross sectional area after a feed. Whole gut motility was assessed at both 3 and 6 weeks of age by measuring the whole gut transit time (WGTT) of the marker carmine red. RESULTS: There was no significant difference between groups in their gastric half emptying time, median difference (95% confidence interval) 2.6 (-5.9, 13.9) minutes. The WGTT was significantly faster (p < 0.05) in group TF at both 3 and 6 weeks; median difference -13 (-47, -0.1) and -12.5 (-44, -0.5) hours, respectively. CONCLUSIONS: Trophic feeding enhances whole gut motility but not gastric emptying. This effect could subsequently improve milk tolerance in sick preterm infants. (+info)Visual parameters define the phase and the load of contractions in isolated guinea pig ileum. (7/712)
How the movements of the intestinal walls relate to luminal pressures and outflow remains incompletely understood. We triggered the peristaltic reflex in the isolated ileum of the guinea pig and quantified wall movements through computerized measurements of diameter changes. Contractions developed as indentations close to the upstream end of the loop. The indentations deepened and expanded in length. The downstream shoulder of contractions started and stopped to propagate before the upstream shoulder. Shoulders differed in their length and gradient over most of the duration of the contraction, and this gives the contraction an axial asymmetry. Over the course of individual contractions, the length of the indented segment correlated well with the luminal pressure. Contractions in response to large volumes generated long indented segments and high luminal pressures. The onset and the end of pressure waves and of outflow did not necessarily coincide with the onset and end of visual parameters of contractions. These findings indicate that objective visual parameters might be useful to describe and to classify contractions. (+info)Modeling intermittent digesta flow to calculate glucose uptake capacity of the bovine small intestine. (8/712)
To test the hypothesis that the uptake capacity of the bovine small intestine for glucose is upregulated to match or slightly exceed glucose delivery, glucose was continuously infused into the proximal duodenum of four cannulated holstein heifers. Every 3 days, infusion rates were increased by an average of 34 mmol/h. A model of glucose disappearance from multiple boluses of intestinal digesta was used to estimate the transporter maximum velocity and functional maximum uptake capacity for the entire small intestine from average ileal glucose flows during the third day of each period. Because of its intermittency, digesta flow remained independent of simulated transit time. For each unit increase in glucose infusion rate, uptake capacity increased by only 0.55 units. Excess capacity for glucose uptake was approximately twofold in forage-fed cattle and declined to below delivery at infusions of >208 mmol/h added glucose, approximately three times the normal load. Calculations for cattle, sheep, and rats indicate that the glucose transport capacity of the small intestine is typically underutilized because of a fraction of time that transporters are not in contact with digesta. (+info)
Colonic Transit Time Validation Study - Tabular View - ClinicalTrials.gov
The effect of chilli and its pungent ingredient capsaicin on gastrointestinal transit in the rat | [email protected]
Bowel transit time | Article about bowel transit time by The Free Dictionary
Bowel Transit Time
Diagnostics | Free Full-Text | Scintigraphic Small Intestinal Transit Time and Defaecography in Patients with J-Pouch
Effects of peptide YY (PYY) on mouth to caecum intestinal transit time and on the rate of gastric emptying in healthy...
FTA: Disappointed with DBT, Has Adverse Impacts on Transit - Seattle Transit Blog
Montisci, M.J., Dembri, A., Giovannuci, G., Chacun, H., Duchene, D. and Ponchel, G (2001) Gastrointestinal Transit and...
Health Care Deal News, August 12, 2013 - Kolberg, Kravis Roberts & Co. (NYSE: KKR) Followed its June Acquisition of PRA...
Obesity and Functional Gastrointestinal Disorders
Friday fun poll: ever carry something really cumbersome on transit? - The Buzzer blog
Solabegron - Wikipedia
The Effect of Aqueous Root Extract of |i|Watherian Indica|/i| on Gastrointestinal Smooth Muscle Activity
| Nigerian...
The benefits of getting stronger
PASPERAN - MEDICO LABS.
Trumps infrastructure plan is a rare, and potentially bipartisan, feel good moment
Rapid gastric and intestinal transit is a major determinant of...
Hillslope permeability architecture controls on subsurface transit time distribution and flow paths<...
Patente US7102571 - Offset stacked patch antenna and method - Google Patentes
Metro Vancouver transit issues Archives - Daryls dialogue
transit planning Archives - Daryls dialogue
Scott Sosnowski on Hybrid Transit Models - MV Transportation
Slowed intestinal transit - What do do? | Page 2 | Phoenix Rising ME / CFS Forums
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Northside Hospital
- Bowel transit time
trial data
Plus it
Underwater Kinetics 1022 Transit Case :: Marine Products : Marine Accessories
A Brief Rundown of - Chudinova
Direct measurement of transit time in the stomachs and intestine of dairy cows - pdf descargar
Intestinal bacteria influence food transit through the gut
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Gastrointestinal tract
"Gastrointestinal Transit: How Long Does It Take?". Colorado State University. Keendjele, Tuwilika P. T.; Eelu, Hilja H.; ... Gastrointestinal cancer may occur at any point in the gastrointestinal tract, and includes mouth cancer, tongue cancer, ... Gastrointestinal physiology Gut-on-a-chip All pages with titles beginning with Gastrointestinal All pages with titles ... The Wikibook Human Physiology has a page on the topic of: The gastrointestinal system The gastro intestinal tract in the Human ...
Motion
Bowen, R (27 May 2006). "Gastrointestinal Transit: How Long Does It Take?". Pathophysiology of the digestive system. Colorado ...
Transport tetany
Rumen hypomotility, gastrointestinal stasis and anorexia develop. Also may develop tachycardia and rapid, labored respiration. ... It is also known as transit tetany, railroad disease, railroad sickness, or staggers. Early clinical signs include restlessness ...
Bristol stool scale
Strid, H.; Simrén, M.; Störsrud, S.; Stotzer, PO.; Sadik, R. (June 2011). "Effect of heavy exercise on gastrointestinal transit ... "Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology ... The authors of the former paper concluded that the form of the stool is a useful surrogate measure of colon transit time. That ... The research results (see table) indicate that about 1 in 5 people have a slow transit (type 1 and 2 stools), while 1 in 12 has ...
Absorption (pharmacology)
Gastrointestinal transit time Flip-flop kinetics Alsanosi, Safaa Mohammed M.; Skiffington, Craig; Padmanabhan, Sandosh (2014 ... The gastrointestinal tract is lined with epithelial cells. Drugs must pass through or permeate these cells to be absorbed into ... Later, esterases in the gastrointestinal tract (GIT) wall and blood hydrolyze these esters to release the parent drug. Coatings ... Ions cannot passively diffuse through the gastrointestinal tract because the epithelial cell membrane is made up of a ...
Fibre supplements
Hillemeier C (November 1995). "An overview of the effects of dietary fiber on gastrointestinal transit". Pediatrics. 96 (5 Pt 2 ... Irritable bowel syndrome (IBS) is a common gastrointestinal ailment for which dietary soluble fibre is often prescribed as part ... so it has a good gastrointestinal tolerance (it has no sudden and painful release of gas, and the total gas production is much ... gradually increasing the amount over a few days allows the natural bacteria in the gastrointestinal tract to adjust to the ...
Andreas Bernkop-Schnürch
Kali, G; Knoll, P; Bernkop-Schnürch, A (2022). "Emerging technologies to increase gastrointestinal transit times of drug ... Nanosized drug carriers providing a prolonged gastrointestinal residence time". Carbohydr Polym. 300: 120275. doi:10.1016/j. ...
Upper gastrointestinal series
The total time necessary for the test depends on the speed of bowel motility or transit time and may vary between 1 and 3 hours ... whereas the barium enema is called a lower gastrointestinal series (or study). In upper gastrointestinal series examinations, ... An upper gastrointestinal series, also called a barium swallow, barium study, or barium meal, is a series of radiographs used ... Other methods to reduce transit time are to add ice cold normal saline after the administration of barium saline mixture or to ...
Alpha-adrenergic agonist
Hsu, W. H. and Lu, Z.-X. (1984). Amitraz' induced delay of gastrointestinal transit in mice: Mediated by α2 adrenergic ...
Lacticaseibacillus paracasei
A protracted refrigeration period before in vitro gastrointestinal transit (GIT) did not affect or influenced very weakly cell ... L. paracasei IMPC2.1 may be a chemoprophylactic in gastrointestinal cells. Gastrointestinal cells are susceptible to apoptosis ... "Safety and Stability of Two Potentially Probiotic Lactobacillus Strains After In Vitro Gastrointestinal Transit". Probiotics ... paracasei 8700:2 has been isolated from healthy human gastrointestinal mucosa and human feces. Strain 8700:2 was also found to ...
Neurogenic bowel dysfunction
Faaborg, P M; Christensen, P; Rosenkilde, M; Laurberg, S; Krogh, K (2010-11-23). "Do gastrointestinal transit times and colonic ... The gastrointestinal tract has a complex control that relies on coordinated interaction between muscular contractions and ... An objective method used to evaluate the motility of the colon and help with diagnosis is the colon transit time. Another ... This results in less smooth muscle contraction of the colon, increasing the colon transit time. The reduced dopamine levels ...
Surgical stress
Naitoh, T; Garcia-Ruiz, A; Vladisavljevic, A; Matsuno, S; Gagner, M (Nov 2002). "Gastrointestinal transit and stress response ... Gastrointestinal Endoscopy. 72 (2): 373-80. doi:10.1016/j.gie.2010.01.066. PMID 20537637. Höglund, OV; Olsson, K; Hagman, R; ...
Prucalopride
"Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation ... Bouras EP, Camilleri M, Burton DD, McKinzie S (May 1999). "Selective stimulation of colonic transit by the benzofuran 5HT4 ... The most frequently reported side effects are headache and gastrointestinal symptoms (abdominal pain, nausea or diarrhea). Such ...
Morphine
The gastrointestinal effects of morphine are mediated primarily by μ-opioid receptors in the bowel. By inhibiting gastric ... emptying and reducing propulsive peristalsis of the intestine, morphine decreases the rate of intestinal transit. Reduction in ... In clinical settings, morphine exerts its principal pharmacological effect on the central nervous system and gastrointestinal ... colitis or other gastrointestinal afflictions related to motility, and problems with weight control in either direction In ...
Solabegron
May 2008). "Dose-response effect of a beta3-adrenergic receptor agonist, solabegron, on gastrointestinal transit, bowel ... Gastrointestinal and Liver Physiology. 294 (5): G1114-9. doi:10.1152/ajpgi.00051.2008. PMID 18372395. Kelleher DL, Hicks KJ, ...
TRIMU 5
In addition to analgesia, TRIMU-5 inhibits gastrointestinal transit, a known effect of μ2-opioid receptor activation. Tive LA, ...
Prokinetic agent
Research into the prokinetic effects of probiotics on the gastrointestinal tract has also been conducted in humans. ... Bifidobacterium bifidum in combination with Lactobacillus acidophilus accelerated small intestine transit in rats. ... They are used to treat certain gastrointestinal symptoms, including abdominal discomfort, bloating, constipation, heart burn, ... Higher acetylcholine levels increase gastrointestinal peristalsis and further increase pressure on the lower esophageal ...
Corydaline
... exhibits gastrointestinal modulatory, antinociceptive, anti-allergic, and anti-parasitic activities. Corydaline (1 ... In animal models, corydaline increases gastric emptying and small intestine transit speed and induces gastric relaxation. In ...
Inulin
Due to its resistance to digestive enzymes, inulin resists absorption during its transit through the upper gastrointestinal ... Inulin's health effects had been studied in small clinical trials, which showed that it causes gastrointestinal adverse effects ... "Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring ...
Synucleinopathy
Symptoms include upper gastrointestinal tract dysfunction such as delayed gastric emptying or lower gastrointestinal ... dysfunction, such as constipation and prolonged stool transit time. Urinary retention, waking at night to urinate, increased ... From chewing to defecation, alpha-synuclein deposits affect every level of gastrointestinal function. ...
Magnesium deficiency
... reduced gastrointestinal absorption or increased gastrointestinal loss due to rapid gastrointestinal transits. Kidney causes ... Magnesium deficiency may result from gastrointestinal or kidney causes. Gastrointestinal causes include low dietary intake of ... Insufficient selenium, vitamin D or sunlight exposure, or vitamin B6.[citation needed] Gastrointestinal causes: the distal ...
Velusetrag
January 2010). "Effects of Velusetrag (TD-5108) on gastrointestinal transit and bowel function in health and pharmacokinetics ... Velusetrag showed accelerated intestinal and colonic transit after single dosing and accelerated gastric emptying after ... and lower gastrointestinal motility disorders including chronic idiopathic constipation and irritable bowel syndrome. It is a ...
6β-Naltrexol
... a peripherally selective opioid antagonist that inhibits morphine-induced slowing of gastrointestinal transit: an exploratory ... 41-. ISBN 978-0-19-923664-0. Hipkin, R. William; Dolle, Roland E. (2010). "Opioid Receptor Antagonists for Gastrointestinal ...
Pteropus
Tedman, RA; Hall, LS (1985). "The Morphology of the Gastrointestinal Tract and Food Transit Time in the Fruit Bats Pteropus ... Even though flying foxes can have a gut transit time as fast as 12 minutes, seeds can be retained in the gut for as long as 20 ...
Beta3-adrenergic agonist
"A Study To Investigate The Effect Of Solabegron (GW427353) On Gastrointestinal Transit In Healthy Volunteers - Full Text View ...
Quorum sensing
... becomes active during the transit of Salmonella enterica through the gastrointestinal tract of turtles". PLOS ONE. 3 (7): e2826 ... Salmonella does not detect AHL when passing through the gastrointestinal tracts of several animal species, suggesting that the ... However, SdiA does become activated when Salmonella transits through turtles colonized with Aeromonas hydrophila or mice ...
Magnetic marker monitoring
Magnetically marked pharmaceutical dosage forms to monitor gastrointestinal transit by biomagnetic measurements, Pharm. ... The magnetic capsule delivers drugs to any targeted location in the gastrointestinal tract. The way the capsule takes is ...
Domperidone
... can be used to increase the transit of food through the stomach by increasing gastrointestinal peristalsis and ... the drug is indicated in upper gastrointestinal motility disorders and to prevent gastrointestinal symptoms associated with the ... Poor gastrointestinal function, nausea and vomiting is a major problem for people with Parkinson's disease because most ... There is an exception for use in people with treatment-refractory gastrointestinal symptoms under an FDA Investigational New ...
Cat food
Non-fermentable fibers helps with satiety, maintenance of a normal intestinal transit time and gastrointestinal motility as ... Cells of the gastrointestinal tract are constantly dying and being replaced by new cells, which requires a lot of energy. The ... The addition of fiber at optimal levels in a diet is essential for the normal function and health of the gastrointestinal tract ... Vitamin E as an antioxidant in gastrointestinal health cat food diets can have a positive effect of improving the animal's ...
Zoopharmacognosy
Another possible mode of action is that the ingested material may initiate a purging response of the gastrointestinal tract by ... This substantially decreases gut transit time, causing worm expulsion and interruption in the life cycle of parasites. This, or ... It has been proposed that for primates, there are four hypotheses relating to geophagy in alleviating gastrointestinal ... Villalba JJ, Miller J, Ungar ED, Landau SY, Glendinning J (2014). "Ruminant self-medication against gastrointestinal nematodes ...
Postcholecystectomy syndrome
Non-biliary causes of PCS may be caused by a functional gastrointestinal disorder, such as functional dyspepsia. Chronic ... February 2010). "Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel ... Gastrointestinal Endoscopy. 68 (1): 69-74. doi:10.1016/j.gie.2007.09.046. PMID 18577477. Schmidt M, Søndenaa K, Dumot JA, ... "Post-cholecystectomy symptoms were caused by persistence of a functional gastrointestinal disorder". World Journal of ...
Aspiration pneumonia
While studies have suggested that thickening liquids can decrease aspiration through slowed pharyngeal transit time, they have ... an acid environment is needed to kill the organisms that colonize the gastrointestinal tract; agents, such as proton pump ... especially conditions causing dysfunction of the upper gastrointestinal system. Identifying these conditions before the ...
Timeline of the COVID-19 pandemic in Massachusetts
He had been sick with gastrointestinal problems and was in cardiac arrest during the flight. On March 16, Massachusetts State ... Later that evening, the MBTA announced that 18 transit workers had tested positive for the virus. In addition, the Boston ... The measure was targeted at large events and exempted most workplaces, transit buildings, polling locations, government ...
Antimicrobial
Kellermayer R (November 2013). "Prospects and challenges for intestinal microbiome therapy in pediatric gastrointestinal ... antimicrobial copper alloys are being installed in some healthcare facilities and subway transit systems as a public hygienic ... disorders". World Journal of Gastrointestinal Pathophysiology. 4 (4): 91-3. doi:10.4291/wjgp.v4.i4.91. PMC 3829459. PMID ...
Dementia with Lewy bodies
... or lower gastrointestinal dysfunction (such as constipation and prolonged stool transit time). Persons with Lewy body dementia ... Problems with gastrointestinal function can affect medication absorption. Constipation can present a decade before diagnosis, ... Heart function and every level of gastrointestinal function-from chewing to defecation-can be affected, constipation being one ... From chewing to defecation, alpha-synuclein deposits affect every level of gastrointestinal function. Almost all persons with ...
Appendicitis
However, a prolonged transit time was not observed in subsequent studies. Diverticular disease and adenomatous polyps was ... Liu B, Ramalho M, AlObaidy M, Busireddy KK, Altun E, Kalubowila J, Semelka RC (August 2014). "Gastrointestinal imaging- ... Burkitt DP, Walker AR, Painter NS (December 1972). "Effect of dietary fibre on stools and the transit-times, and its role in ... Gear JS, Brodribb AJ, Ware A, Mann JI (January 1981). "Fibre and bowel transit times". The British Journal of Nutrition. 45 (1 ...
Rectal discharge
This type of lesion may not cause discharge intrinsically, but instead, allow transit of liquid stool components and mucus. ... Vernava AM, Moore BA, Longo WE, Johnson FE (1997). "Lower gastrointestinal bleeding". Dis. Colon Rectum. 40 (7): 846-58. doi: ...
Melena
Gastrointestinal Bleeding". In Longo, Dan L; Fauci, Anthony S; Kasper, Dennis L; Hauser, Stephen L; Jameson, J. Larry; Loscalzo ... therefore if transit time is less than 14 hours the patient will have hematochezia, and if greater than 14 hours the patient ... Causes of upper gastrointestinal bleeding that may result in melena include malignant tumors affecting the esophagus, stomach ... However, any bleeding within the upper gastrointestinal tract or the ascending colon can lead to melena. Melena may also be a ...
ELOM-080
With respect to gastrointestinal tolerability for ELOM-080, the patients were found to be satisfied to very satisfied ... The beat frequency of these cilia is accelerated by ELOM-080, thus shortening the mucus transit time. Thus, in one study, the ...
Kostanay Region
On territory of area pass from the north on the south and a southeast the main transit roads connecting the regional center ... Treatment is carried out: a gastrointestinal tract, respiratory system, postoperative rehabilitation and a mud baths. Kamshat ...
Water supply and sanitation in Canada
... public transit and green energy, as well as other projects; CAN$25 million a year in base funding to each province and ... which may cause gastrointestinal diseases or increased risks for cancer. According to a 2001 Indian and Northern Affairs/ ...
Laxative
Lubricant laxatives also increase the weight of stool and decrease intestinal transit time. Properties Site of action: colon ... making it easier for them to move through the gastrointestinal tract. Properties Site of action: small and large intestines ... laxatives act to speed up the transit of feces through the large intestine, which occurs after the absorption of nutrients in ... are motility stimulants that work through activation of 5-HT4 receptors of the enteric nervous system in the gastrointestinal ...
Endoluminal capsule monitoring
The patient ingests the capsule and while it transits through the gastrointestinal system, it sends signals to the outside, ... The system is normally used for research purposes or for diagnosing long term changes in gastrointestinal physiological ...
Disability in the United States
II Transportation Public transportation should be customized so that disabled people may have easy access to public transit. ... or heart disease Celiac disease Cerebral palsy Deaf or hard of hearing Depression or anxiety Diabetes Epilepsy Gastrointestinal ...
LGR5
This suggests that LGR5 stem cells give rise to transit-amplifying cells, which migrate towards the isthmus where they ... Varying expression profile of LGR5 was also observed in different stages of gastrointestinal cancers, which suggests that the ... the transit-amplifying cells. Tracing has revealed that LGR5 is a marker of adult intestinal stem cells. The high turnover rate ... ve stem cells fuel the actual hair follicle shaft upon migration of transit-amplifying cells into the dermal papilla. In ...
Pancreatic elastase
Human pancreatic elastase 1 (E1) remains undegraded during intestinal transit. Therefore, its concentration in feces reflects ... mild or moderate pancreatic insufficiency Diagnosis/exclusion of pancreatic involvement in association with gastrointestinal ...
Cerebral palsy
In addition to these, functional gastrointestinal abnormalities contributing to bowel obstruction, vomiting, and constipation ... and transportation difficulties due to limited wheelchair access or public transit that can accommodate children with CP. For ...
Pharmacokinetics of progesterone
The transit time of red blood cells from capillaries and the release of steroid hormones from red blood cells are both very ... The very low bioavailability of oral progesterone is due to the fact that it is poorly absorbed from the gastrointestinal tract ... With oral administration, progesterone is rapidly metabolized in the gastrointestinal tract and liver. As many as 30 different ... progesterone was poorly absorbed and rapidly metabolized in the gastrointestinal tract, liver and most tissues, and then ...
Deaths in January 1995
Joseph F. Sullivan (January 7, 1995). "Walter Rand, 75, New Jersey Senator And Transit Expert". The New York Times. p. 1 29. ... Peter Cook, 57, English comedian and writer, gastrointestinal bleeding. Sterling Dow, 91, American classical archaeologist, ...
Blackbirding
From 1875 to 1880, at least 443 Kanakas died in the Maryborough region from gastrointestinal and pulmonary disease at a rate 10 ... a figure which does not include those who expired in transit or who were killed in the recruitment process. This represents a ...
South East England
Novartis manufacture and their large Horsham Research Centre (respiratory and gastro-intestinal, former Ciba-Geigy) is next to ... closed in July with production of the Transit moving to the Ford Otosan plant in Gölcük, Kocaeli (Turkey). Skandia Insurance ...
Relamorelin
December 2015). "Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized ... Valentin N, Acosta A, Camilleri M (June 2015). "Early investigational therapeutics for gastrointestinal motility disorders: ... Drugs acting on the gastrointestinal system and metabolism, Experimental drugs, Ghrelin receptor agonists, Growth hormone ...
Polycarbophil calcium
2005). "Colonic transit, bowel movements, stool form, and abdominal pain in irritable bowel syndrome by treatments with calcium ... Monovalent metal ions such as sodium and potassium ions in gastrointestinal fluid do not reduce the equilibrium swelling of ... The bulky mass stimulates the intestinal muscles, speeding stool transit time through the colon. Results usually occur within ... with IBS-diarrhea and twelve with IBS-constipation were given calcium polycarbophil for eight weeks and their colon transit ...
Superior mesenteric artery syndrome
Gastrointestinal tract disorders, Diseases of arteries, arterioles and capillaries, Syndromes affecting the gastrointestinal ... as well as a delay in transit of four to six hours through the gastroduodenal region. Standard diagnostic exams include ... According to a 1956 study, only 0.3% of patients referred for an upper-gastrointestinal-tract barium studies fit this diagnosis ... However, the reason for the persistence of gastrointestinal symptoms even after surgical correction in some cases has been ...
Gertrude M. Clarke
Her thesis was titled, "A Reassessment of Gastrointestinal Dose from a Continental United States Nuclear Weapons Test". In 1980 ... "Generation of Electromagnetic Radiation by the Interaction of Charged Particle Beams Transiting Periodic Structures" primarily ...
Effect of wheat bran on weight of stool and gastrointestinal transit time: a meta analysis | The BMJ
Effect of wheat bran on weight of stool and gastrointestinal transit time: a meta analysis. Br Med J (Clin Res Ed) 1988; 296 ... Effect of wheat bran on weight of stool and gastrointestinal transit time: a meta analysis Br Med J (Clin Res Ed) 1988; 296 : ... Effect of wheat bran on weight of stool and gastrointestinal transit time: a meta analysis ... Effect of wheat bran on weight of stool and gastrointestinal transit time: a meta analysis ...
Effect of alvimopan and codeine on gastrointestinal transit: A randomized controlled study<...
Effect of alvimopan and codeine on gastrointestinal transit: A randomized controlled study. Clinical Gastroenterology and ... Effect of alvimopan and codeine on gastrointestinal transit : A randomized controlled study. In: Clinical Gastroenterology and ... Dive into the research topics of Effect of alvimopan and codeine on gastrointestinal transit: A randomized controlled study. ... Effect of alvimopan and codeine on gastrointestinal transit : A randomized controlled study. / Gonenne, Jonathan; Camilleri, ...
Gastrointestinal Transit Model - Melior Discovery
This gastrointestinal model is designed to identify compounds that produce effects on bowel function and cause inhibition on ... Interested in running a Gastrointestinal Transit study?. If you are interested in learning more about the Gastrointestinal ... Gastrointestinal Transit Model. Discover how Meliors unique phenotypic screening platforms can uncover the untapped value of ... Like other GI motility models the Gastrointestinal Transit model, is typically a one-day model evaluating acute effects of test ...
Gastrointestinal Complications (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf
Get detailed information about gastrointestinal complications and ways to manage them in this clinician summary. ... Gastrointestinal complications (e.g., constipation, bowel obstruction, diarrhea) can be tumor or treatment related and are ... Opioids bind to receptors within the gastrointestinal tract and reduce diarrhea by reducing transit time. Loperamide is the ... This agent inhibits the release of several gastrointestinal hormones and reduces gastrointestinal secretions.[22,23][Level of ...
Bowel transit time: MedlinePlus Medical Encyclopedia
Bowel transit time refers to how long it takes for the food to move from the mouth to the end of the intestine (anus). ... Sleisenger and Fordtrans Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 19. ... The bowel transit time varies, even in the same person.. *The average transit time through the colon in someone who is not ... The bowel transit time test is rarely done these days. Instead, bowel transit is often measured with small probes called ...
Effects of Dopamine, Dobutamine, and Dopexamine on Microcirculatory Blood Flow in the Gastrointestinal Tract during Sepsis and...
Ultrasonic Transit Time Flowmetry.. Blood flow in the SMA was continuously measured throughout the experiments with ultrasonic ... An ultrasonic transit time flow probe (Transonic Systems, Ithaca, NY) was placed around the vessel and connected to an ... 6-11This concept is based on the assumption that the gastrointestinal mucosa receives its share of increased systemic and ... None of these β-adrenergic agents, however, increased micro-circulatory blood flow either in the gastrointestinal mucosa or in ...
Chromium (Cr) Toxicity: What Is the Biologic Fate of Chromium in the Body? | Environmental Medicine | ATSDR
Public Health Service Task Force Recommendations for the Use of
Antiretroviral Drugs in Pregnant Women Infected with HIV-1 for...
PDF) In vitro digestibility of expanded pork skin and rawhide chews, and digestion and metabolic characteristics of expanded...
Historically, measurement of gastrointestinal transit time has required collection and X-raying of faecal samples for up to 7 d ... GET = gastric emptying time; SBTT = small bowel transit time; CTT = colon transit time; SLBTT = small and large bowel transit ... of the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility capsule sys- ... The use of a wireless motility device (SmartPill(R)) for the measurement of gastrointestinal transit time after a dietary fibre ...
Effect of meal ingestion on ileocolonic and colonic transit in health and irritable bowel syndrome
... whereas colonic transit is blunted in IBS-C. ... Gastrointestinal Transit / physiology* * Humans * Ileum / ... Effect of meal ingestion on ileocolonic and colonic transit in health and irritable bowel syndrome Dig Dis Sci. 2010 Feb;55(2): ... Ileocolonic transit (ICT) was evaluated before (colonic filling [CF]3h) and immediately after (CF4 h) a standard lunch at 3 h ... Conclusions: After feeding, ICT is increased in IBS-D, whereas colonic transit is blunted in IBS-C. ...
Digestive Disease Week 2007 (DDW)
Gastrointestinal transit measurements in mice with 99mTc-DTPA-labeled activated charcoal using NanoSPECT-CT | EJNMMI Research |...
... was used to delay the GI transit. The transit time measured as the peak radioactivity occurring in the rectum was 6 to 7 h ... Here, we describe a method for studying the GI transit time using technetium-labeled activated charcoal ... The exact distribution and movement of radioactivity in the gastrointestinal tract was measured at intervals of 1, 3, 6, 12, ... we present the first non-invasive study of mouse GI transit time, allowing clear differentiation between vehicle- and ...
Effects of Posture and Meal Volume on Gastric Emptying, Intestinal Transit, Oral Glucose Tolerance, Blood Pressure and...
Intestinal Transit, Oral Glucose Tolerance, Blood Pressure and Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass. ... Intestinal Transit, Oral Glucose Tolerance, Blood Pressure and Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass, ... intestinal transit, hormones, absorption, glycaemia, blood pressure and gastrointestinal (GI) symptoms after gastric bypass ( ... intestinal transit, hormones, absorption, glycaemia, blood pressure and gastrointestinal (GI) symptoms after gastric bypass ( ...
Gastro-intestinal transit of solid oral dosage forms: Imaging studies using Magnetic Marker Monitoring technique - SocraTec R&D...
Altered gastrointestinal microbiota in irritable bowel syndrome and its modification by diet: probiotics, prebiotics and the...
Altered gastrointestinal microbiota in irritable bowel syndrome and its modification by diet: probiotics, prebiotics and the ... 2013) Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice. Gastroenterology 144, ... 13. Eswaran, S, Muir, J & Chey, WD (2013) Fiber and functional gastrointestinal disorders. Am J Gastroenterol 108, 718-727. ... The gastrointestinal microbiota. The GI tract harbours 1014 bacteria, ten times more than the total number of cells in the ...
Grape seed powder increases gastrointestinal motility
GSP increased the intestinal transit rate in normal mice and in mice with acetic acid-induced GI motility disorder. In addition ... Al-Shboul O. The importance of interstitial cells of cajal in the gastrointestinal tract. Saudi J Gastroenterol. 2013;19:3-15 ... Camilleri M. Gastrointestinal Hormones and Regulation of Gastric Emptying. Curr Opin Endocrinol Diabetes Obes. 2019;26:3-10 ... Regulation of gastrointestinal motility-insights from smooth muscle biology. Nat Rev Gastroenterol Hepatol. 2012;9:633-45 ...
Nutrients | Free Full-Text | Growth, Gastrointestinal Tolerance and Stool Characteristics of Healthy Term Infants Fed an Infant...
Anthropometric measurements, gastrointestinal tolerance indexes and stool characteristics were assessed at baseline, and 7 and ... gastrointestinal tolerance and stool characteristics from those fed an infant formula containing intact whey protein (IWP-F, ... but no significant gastrointestinal tolerance improvement was observed in HWP-F group. ... Correlates with Total Gastrointestinal Transit Time in Children. J. Pediatr. 2013, 162, 1188-1192. [Google Scholar] [CrossRef ...
Diaper Rash: Practice Essentials, Pathophysiology, Etiology
Effect of Flaxseed on Bile Tolerances of Lactobacillus acidophilus, Lactobacillus bulgaricus, and Streptococcus thermophilus
bulgaricus Survive Gastrointestinal Transit of Healthy Volunteers Consuming Yogurt. FEMS Microbiology Letters, 250, 185-187. ... Some studies have shown that yogurt bacteria can survive transit through the human gastrointestinal tract since these organisms ... Probiotic Lactobacillus bulgaricus in Alginate-Milk Microspheres and Evaluation of the Survival in Simulated Gastrointestinal ...
CAPSICUM - Therapeutic Powerhouse and Herbal Catalyst... - Article
"The effect of chile on gastrointestinal transit." Journal of Gastroenterology-Hepatol. Jan-Feb, 1992 7 (1): 52-56.: 59 ... Capsicum and the Gastro-Intestinal Tract In 1992, researchers tested the effect of chile or Capsicum on gastrointestinal ... To add transit time to the list of functions Capsicum boosts comes as somewhat of a surprise and additional benefit. Capsicum ... Capsicum stimulates eve rything from blood flow to peristaltic action in the stomach, to intestinal transit time. The re m a ...
Xofigo (Radium Ra 223 Dichloride): Uses, Dosage, Side Effects, Interactions, Warning
... of radium-223 dichloride from the gastrointestinal tract is influenced by the high variability in intestinal transit rates ... Patients with a slower intestinal transit rate could potentially receive a higher intestinal radiation exposure. It is not ... including monitoring for potential hematological and gastrointestinal toxicity, and consider using medical countermeasures such ... known whether this will result in increased gastrointestinal toxicity.. Special Populations. Pediatric Patients. Safety and ...
Comparison of Barium and Iohexol as Gastrointestinal Contrast Media in Avian Radiography - AAZV 1999 - VIN
Overall transit times were rapid with either iohexol concentration. For the diluted iohexol, readers felt there was more rapid ... Use of iohexol as a gastrointestinal contrast agent in three dogs, five cats, and one bird. J Am Vet Med Assoc 202:624-627. ... The indications for gastrointestinal contrast radiography in avian medicine are generally the same as in mammals. Studies to ... From these results, a contrast study of the avian gastrointestinal tract can be performed in 1 hr in most birds. Films should ...
医生与医务人员
Frontiers | The Potential Role of Gut Mycobiome in Irritable Bowel Syndrome
... which is a common functional gastrointestinal disorder with a high incidence all over the world. However, investigations to ... which is a common functional gastrointestinal disorder with a high incidence all over the world. However, investigations to ... 2013). Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice. Gastroenterology 144, ... 2018). Fungi in gastrointestinal tracts of human and mice: from community to functions. Microb. Ecol. 75, 821-829. doi: 10.1007 ...
Refinement Database | Animal Welfare Institute
The objective of this study was to assess the impact on gastrointestinal transit time of ketamine-midazolam (KMZ) versus ... Postanaesthetic effects of ketamine-midazolam and ketamine-medetomidine on gastrointestinal transit time in rabbits ... Gastrointestinal stasis is a common perianaesthetic complication in rabbits. ...
A New View of Occult and Obscure Gastrointestinal Bleeding | AAFP
About one half of patients with gastrointestinal bleeding do not have an obvious source of the bleeding. In those patients, ... In patients without symptoms indicating an upper gastrointestinal tract source or in patients older than 50 years, colonoscopy ... Occult gastrointestinal bleeding usually is discovered when fecal occult blood test results are positive or iron deficiency ... Patients are encouraged to eat foods high in fiber for one week before testing to cause more rapid stool transit. Hemoccult II ...
The Added Diagnostic Value of Liquid Gastric Emptying Compared with Solid Emptying Alone | Journal of Nuclear Medicine
AMS Task Force Committee on gastrointestinal transit: measurement of gastrointestinal transit. Dig Dis Sci. 2005;50:989-1004. ... Will Comprehensive Assessment from Esophagus to Large Bowel Revive the Momentum for Radionuclide Gastrointestinal Transit ... Relationships between oesophageal transit and solid and liquid gastric emptying in diabetes mellitus. Eur J Nucl Med. 1990;18: ... This is stated in gastrointestinal (4-6) and nuclear medicine review articles (13-15), textbooks (1,16), and Society of Nuclear ...
TractMotilityDisordersIrritable bowel sySymptomsMicrobiotaAbsorptionGastricIntestinal transit timeColonic transit timeFecalTimeFunctional gastrointestinal diseasesConstipationRadiographyDiscomfortDiseasesAdverse effectsBariumHelicobacterSymptomDigestionSmall-bowelDiarrheaHematocheziaRatsStudyToleranceDietBowel transitStool transitIncidenceDigestivePatientsMiceEffectsFoodSystemic
Tract30
- However, increased systemic flow did not reach the microcirculation in the gastrointestinal tract. (asahq.org)
- Insufficient blood flow to the gastrointestinal tract during sepsis may provoke gut mucosa barrier dysfunction, resulting in bacterial translocation and multiple organ failure. (asahq.org)
- Two experiments were conducted to determine in vitro DM digestibility of expanded pork skin chews and rawhide chews, and apparent total tract digestibility (ATTD), gastrointestinal transit time, and blood metabolite measurements in healthy adult dogs fed a weight control commercial diet and expanded pork skin chews. (researchgate.net)
- The exact distribution and movement of radioactivity in the gastrointestinal tract was measured at intervals of 1, 3, 6, 12, and 22 h by SPECT-CT. (springeropen.com)
- Measurement of gastrointestinal (GI) transit time is a very useful clinical and research technique for evaluating the motility disorders in the gastrointestinal tract. (springeropen.com)
- Interstitial cells of Cajal (ICCs) are pacemaker cells in the gastrointestinal (GI) tract. (medsci.org)
- Most mammals obtain energy from food nutrients through the gastrointestinal (GI) tract [ 8 ]. (medsci.org)
- Some studies have shown that yogurt bacteria can survive transit through the human gastrointestinal tract since these organisms can be recovered in feces [19] [20]. (scirp.org)
- In all three species, films made within the first hour of administration of contrast media will show all portions of the gastrointestinal tract opacified, with the exception of the cloaca. (vin.com)
- The composition of fungi on the skin, oral, airway, genitourinary tract, and gastrointestinal tract has been sequenced through culture-dependent or -independent methods ( Huffnagle and Noverr, 2013 ). (frontiersin.org)
- In patients without symptoms indicating an upper gastrointestinal tract source or in patients older than 50 years, colonoscopy usually is performed first. (aafp.org)
- It is normal to lose 0.5 to 1.5 mL of blood daily in the gastrointestinal tract, 3 and melena usually is identified when more than 150 mL of blood are lost in the upper gastrointestinal tract. (aafp.org)
- The findings from Snyder Institute for Chronic Diseases researchers immediately improve the understanding of factors that help regulate the enteric nervous system, the system of nerves that control the gastrointestinal tract. (indiatimes.com)
- Apparatus 3 (reciprocating cylinder) was develop in recognition of the need for a system that sequentially alters the dissolution conditions to mimic the gastrointestinal tract, so that in vitro-in vivo correlations can be established. (pharmtech.com)
- HN019 improves average gut transit time and promotes healthy daily functions of the upper and lower gastrointestinal tract. (mindbodygreen.com)
- Very quickly, however, members of the genus Bifidobacterium start to colonize the human gastrointestinal tract and exert positive health benefits on their infant host. (bodyecology.com)
- Much of this waste is then dumped into the gastrointestinal tract for final disposal. (ibstreatmentcenter.com)
- Dietary fiber acts on the gastrointestinal tract through several mechanisms, including increased fecal mass with mechanical stimulation/irritation of the colonic mucosa with increasing secretion and peristalsis, and the actions of fermentation byproducts, particularly short-chain fatty acids, on the intestinal microbiota, immune system and the neuroendocrine system of the gastrointestinal tract. (spandidos-publications.com)
- Meanwhile both cayenne pepper and cinnamon contain capsaicin , a compound that triggers the TRVP1 receptors located in your mouth, throughout your body, and gastrointestinal (GI) tract. (naturalnews.com)
- Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. (bvsalud.org)
- This study tested the effects of ß-methylphenylethylamine (ß-MPEA) and octopamine on contractile parameters of the gastrointestinal tract in rats. (bvsalud.org)
- Gastrointestinal tract area was estimated by some combination of autopsy data and nightmartish in vivo mapping exercises. (derangedphysiology.com)
- Then, if one takes into account the variable oroanal length of the gastrointestinal tract in humans, one can use simple maths to work out the surface area of the human digestive tract. (derangedphysiology.com)
- The history and physical examination of the patient provide crucial information for the initial evaluation of persons presenting with a gastrointestinal (GI) tract hemorrhage. (medscape.com)
- the redder the stool, the more rapid the transit, which suggests a large upper tract hemorrhage. (medscape.com)
- Physiology of gastrointestinal tract. (psyllium.fr)
- Motility is a term used to describe the contraction of the muscles that mix and propel contents in the gastrointestinal (GI) tract. (iffgd.org)
- The warm water serves to stimulate the gastrointestinal tract and peristalsis-the waves of muscle contractions within the intestinal walls that keep things moving. (healthywealthyhq.com)
- bland d. a regular d. omitting foods that mechanically or chemically irritate the gastrointestinal tract . (en-academic.com)
- A prenatal diagnosis can be performed by measuring the alpha-fetoprotein produced by the foetal gastrointestinal tract and liver as well as foetal ultrasonography, which is considered the gold standard for diagnosis. (bvsalud.org)
Motility14
- Similar to the Colonic Propulsion Motility model , the Gastrointestinal Transit Model (sometimes call the Charcoal Meal Model) is also commonly used to evaluate bowel motility and further reflect GI function. (meliordiscovery.com)
- At Melior, we have validated this model by examining morphine's effect on inhibiting gastrointestinal motility. (meliordiscovery.com)
- Like other GI motility models the Gastrointestinal Transit model, is typically a one-day model evaluating acute effects of test articles (a single administration). (meliordiscovery.com)
- Camilleri M. Disorders of gastrointestinal motility. (medlineplus.gov)
- However, chew intake did not change transit time as measured by a wireless motility device. (researchgate.net)
- A number of testing methods are available and used frequently by the clinicians to evaluate the symptoms and causes of the GI transit, motility, and drug release in humans. (springeropen.com)
- A variety of methods have been used for assessing GI transit times, motility, and drug release. (springeropen.com)
- GSP increased the intestinal transit rate in normal mice and in mice with acetic acid-induced GI motility disorder. (medsci.org)
- neither sedation nor anesthesia was used to avoid chemical effects on gastrointestinal motility. (vin.com)
- Few studies have demonstrated gastrointestinal motility abnormalities in affected individuals. (who.int)
- Gastrointestinal motility abnormalities have been suggested as a possible cause for symptoms in patients with non-organic recurrent abdominal pain, but very few studies have been done to prove or disprove this. (who.int)
- Case controlled studies were performed in 42 patients and 20 healthy controls to investigate an association between gastric myoelectrical activity (electrogastrography), gastric motility (gastric emptying and antral motility), and oro-caecal transit (small intestinal transit) and non-organic recurrent abdominal pain. (who.int)
- The results showed significantly decreased gastric emptying, decreased antral motility and delayed oro-caecal transit time in patients suggesting that gastrointestinal motility abnormalities may be responsible for generation of symptoms in non-organic recurrent abdominal pain. (who.int)
- Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2011 Oct 23 (10): 935-e398. (cdc.gov)
Disorders12
- Gastrointestinal (GI) disorders are commonly associated with chronic conditions such as diabetes, obesity, and hypertension. (springeropen.com)
- Despite the considerable efforts undertaken by researchers in academia and industry alike during the past two decades, the success rate for effective drug development for irritable bowel syndrome (IBS) and other functional gastrointestinal disorders did not score satisfactorily [ 8 ]. (springeropen.com)
- Researchers can now explore novel ways to treat gastrointestinal disorders using approaches based on these new findings, though the transition to treatment is likely years away. (indiatimes.com)
- The study's findings may impact future treatments for gastrointestinal diseases and disorders such as irritable bowel syndrome, inflammatory bowel disease and slow transit constipation, among others. (indiatimes.com)
- Thompson WG, Irvine EJ, Pare P, Ferrazzi S and Rance L: Functional gastrointestinal disorders in Canada: First population-based survey using Rome II criteria with suggestions for improving the questionnaire. (spandidos-publications.com)
- In the United States, millions of adults have taken some form of probiotic to treat or prevent a variety of conditions, most commonly gastrointestinal (GI) disorders. (uspharmacist.com)
- Over the past two decades, interest in the role of probiotics in improving various conditions has greatly increased, particularly among persons with gastrointestinal (GI) disorders. (uspharmacist.com)
- Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis. (cdc.gov)
- Studies have shown professional bus operators have a high risk of cardiovascular disease, hypertension, gastrointestinal disorders and musculoskeletal problems, as well as psychological health issues, including fatigue, depression and anxiety. (cdc.gov)
- Stress is reported as a main risk factor that leads to adverse health outcomes among professional drivers, especially cardiovascular disease and gastrointestinal disorders. (cdc.gov)
- It is also a great addition to a diet for gastrointestinal disorders . (naturalhealthmessage.com)
- Using the NIH Patient-Reported Outcomes Measurement Information System framework, researchers have developed and validated eight gastrointestinal symptom scales for use in clinical care and research across the full spectrum of GI disorders. (helpforibs.com)
Irritable bowel sy3
- Bran increased the stool weight and decreased the transit time in each study in healthy controls and in patients with the irritable bowel syndrome, with diverticula, and with chronic constipation. (bmj.com)
- Gut microbiota dysbiosis is increasingly considered as a vital factor in the etiopathogenesis of irritable bowel syndrome (IBS), which is a common functional gastrointestinal disorder with a high incidence all over the world. (frontiersin.org)
- Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder. (spandidos-publications.com)
Symptoms6
- The patient with a fecal impaction may present with circulatory, cardiac, or respiratory symptoms rather than with gastrointestinal symptoms. (nih.gov)
- This review describes the role of the gastrointestinal (GI) microbiota in the pathogenesis of IBS and how dietary strategies to manage symptoms impact on the microbial community. (cambridge.org)
- Participants recorded their dietary habits, bowel function, and gastrointestinal symptoms. (unboundmedicine.com)
- Perform stool guaiac testing in patients with gastrointestinal symptoms and in patients older than 50 years. (medscape.com)
- High dietary fat is proven to delay gastric emptying and small intestinal transit, and known to induce gastrointestinal symptoms in patients with functional gastrointestinal disease. (who.int)
- Effects of guar gum, ispaghula and microcrystalline cellulose on abdominal symptoms, gastric emptying, orocaecal transit time and gas production in healthy volunteers. (psyllium.fr)
Microbiota3
- Altered gastrointestinal microbiota in irritable bowel. (cambridge.org)
- Conclusion: there is an important causal influence of the bidirectional brain-gut-microbiota axis in the etiology and exacerbation of clinical manifestations of Autism Spectrum Disorder due to intestinal dysbiosis and gastrointestinal factors of idiopathic origin. (bvsalud.org)
- For infants as being present in most individuals, body sites and including 151 repre- that are vaginally delivered, the initial but with different relative abundanc- sentative gastrointestinal species gut microbiota resembles the moth- es. (who.int)
Absorption4
- 1 ] The longer the transit time of stool in the large intestine, the greater the fluid absorption and the drier and harder the stool becomes. (nih.gov)
- Its significance is based on the fact that for a drug to be effective, it must first be released from the product and dissolve in the gastrointestinal fluids before absorption into the bloodstream can happen. (pharmtech.com)
- In order to predict the impact of meal ingestion on drug absorption, the relationship between the characteristics of a meal and the GE rate was analyzed, characterized and integrated into a novel model for gastrointestinal transit and absorption. (page-meeting.org)
- Here, we consider a PBPK model as a whole-body model describing systemic disposition linked to a mechanistic absorption model such as the advanced compartmental absorption and transit (ACAT) model [ 2 ]. (springer.com)
Gastric4
- Our aim was to evaluate the ability of a peripheral μ-opioid antagonist, alvimopan, to reverse the effect of codeine on gastric, small-bowel, and colonic transit time in healthy volunteers. (elsevier.com)
- Gastric emptying, small-bowel, and colonic transit were measured by scintigraphy using a 99m-labeled technetium egg meal and 111-labeled indium charcoal delivered to the proximal colon via a delayed-release capsule. (elsevier.com)
- Cardiac index was measured with thermodilution, superior mesenteric artery flow was measured with ultrasound transit time flowmetry, and microcirculatory blood flow was continuously measured with a six-channel laser Doppler flowmetry in the gastric, jejunal, and colon mucosa as well as in the kidney, pancreas, and jejunal muscularis. (asahq.org)
- DEVANARAYANA, NM, Gastric myoelectrical activity, gastric emptying time and oro-caecal transit time in children with Recurrent Abdominal Pain Syndrome , University of Kelaniya UK(MED), 2006: p. (who.int)
Intestinal transit time2
- Fecal weight, pH, SCFA and bacterial enzyme activities, total intestinal transit time (TITT), and breath hydrogen were determined. (unboundmedicine.com)
- Consequently, it inhibits the release of acetylcholine and prostaglandins, thereby reducing propulsive peristalsis, and increasing intestinal transit time. (nih.gov)
Colonic transit time2
- Anorectal balloon manometry can be used to assess colonic transit time. (medscape.com)
- This soluble fiber hastens colonic transit time and minimizes the side effects of constipation. (naturalnews.com)
Fecal2
- Occult gastrointestinal bleeding usually is discovered when fecal occult blood test results are positive or iron deficiency anemia is detected. (aafp.org)
- Occult bleeding (i.e., gastrointestinal bleeding that is not visible to the patient or physician) typically is discovered when giron deficiency anemia is detected or the result of a fecal occult blood test (FOBT) is positive. (aafp.org)
Time23
- From these data it is concluded that bran can be expected to be only partially effective in restoring normal stool weight and transit time in patients who are constipated. (bmj.com)
- The primary end points for colonic transit were geometric center of the colonic counts at 24 hours and time for 50% ascending colon emptying. (elsevier.com)
- gastrointestinal transit time. (cdc.gov)
- Bowel transit time refers to how long it takes for the food to move from the mouth to the end of the intestine (anus). (medlineplus.gov)
- This article talks about the medical test used to determine bowel transit time using a radiopaque marker testing. (medlineplus.gov)
- The bowel transit time varies, even in the same person. (medlineplus.gov)
- The average transit time through the colon in someone who is not constipated is 30 to 40 hours. (medlineplus.gov)
- Up to a maximum of 72 hours is still considered normal, although transit time in women may reach up to around 100 hours. (medlineplus.gov)
- The bowel transit time test is rarely done these days. (medlineplus.gov)
- However, their digestion characteristics and gut transit time are virtually unknown. (researchgate.net)
- Here, we describe a method for studying the GI transit time using technetium-labeled activated charcoal diethylenetriaminepentaacetic acid ( 99m Tc-Ch-DTPA) detected by single-photon emission computed tomography (SPECT). (springeropen.com)
- In addition, in order to validate the imaging of GI transient time, loperamide (0.25 mg/animal, n = 3) was used to delay the GI transit. (springeropen.com)
- The transit time measured as the peak radioactivity occurring in the rectum was 6 to 7 h after gavaging of 99m Tc-Ch-DTPA. (springeropen.com)
- Here, we present the first non-invasive study of mouse GI transit time, allowing clear differentiation between vehicle- and loperamide-treated animals. (springeropen.com)
- 2020. Postanaesthetic effects of ketamine-midazolam and ketamine-medetomidine on gastrointestinal transit time in rabbits anaesthetised with isoflurane. (awionline.org)
- The objective of this study was to assess the impact on gastrointestinal transit time of ketamine-midazolam (KMZ) versus ketamine-medetomidine (later antagonised by atipamezole) (KMT-A) in rabbits. (awionline.org)
- OTTAWA: Researchers probing the gut have for the first time discovered specific factors in its workings that in the future may help improve treatment for patients facing the gastrointestinal disease. (indiatimes.com)
- Constipation is a symptom of slow transit time, not unlike rush-hour traffic. (ibstreatmentcenter.com)
- If the intestinal tube is slowed in its transit time, then these toxins are not removed in a timely manner and may even be reabsorbed. (ibstreatmentcenter.com)
- Loperamide prolongs the transit time of the intestinal contents. (nih.gov)
- Ruottinen S, some scientists report that fiber helps by decreasing transit time, and discuss how much fiber is too much. (shiprockhigh.org)
- Insoluble fiber increases stool bulk, decreases transit time of food in the bowel , and decreases constipation and the risk of colon cancer . (en-academic.com)
- it occurs equally in men and women, with a higher prevalence in cultures with a low-fiber diet (which is believed to decrease stool transit time, thereby causing increased intraluminal pressure and resulting in mucosal herniations). (medscape.com)
Functional gastrointestinal diseases3
- IBS is one of the most common functional gastrointestinal diseases with high prevalence worldwide. (frontiersin.org)
- The exact aetiology of this troublesome syndrome is unclear in the majority of patients affected by this condition and attempts have been made to classify them into functional gastrointestinal diseases using Rome II and III criteria. (who.int)
- Clinical and laboratory evaluation revealed organic pathology in less than 24 percent of the affected children, and the majority had functional gastrointestinal diseases. (who.int)
Constipation5
- This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the pathophysiology and treatment of gastrointestinal complications, including constipation, impaction, bowel obstruction, diarrhea, and radiation enteritis. (nih.gov)
- Gastrointestinal complications such as constipation, impaction, bowel obstruction, diarrhea, and radiation enteritis are common problems for patients with cancer. (nih.gov)
- Constipation is relieved more by rye bread than wheat bread or laxatives without increased adverse gastrointestinal effects. (unboundmedicine.com)
- In conclusion, rye bread relieves mild constipation and improves colonic metabolism compared with white wheat bread and commonly used laxatives without increasing gastrointestinal adverse effects. (unboundmedicine.com)
- It regulates transit through the intestine both in cases of constipation, as well as diarrhea. (naturalhealthmessage.com)
Radiography2
- The indications for gastrointestinal contrast radiography in avian medicine are generally the same as in mammals. (vin.com)
- narrowed areas located in the esophageal transit by gastroscopy and radiography. (biomedica.tn)
Discomfort1
- Drug-related gastrointestinal side effects can cause a great deal of discomfort and pain. (meliordiscovery.com)
Diseases3
- These and other gastrointestinal diseases with manifested changes in enteric neural control are all hard to treat. (indiatimes.com)
- As our understanding increases regarding the role the gut microbiome plays in gut health, I think we will ultimately have new ways to diagnose and treat gastrointestinal diseases on an individual level,' added Sharkey. (indiatimes.com)
- Field of application by the gastroenterologist: gastrointestinal diseases, digestive endoscopies, digestive functional investigations. (biomedica.tn)
Adverse effects2
- Although not isotonic, no adverse effects were associated with the use of iohexol as a gastrointestinal contrast agent. (vin.com)
- Gastrointestinal adverse effects did not significantly differ among the study groups. (unboundmedicine.com)
Barium5
- Barium sulfate, iohexol, and half-strength iohexol solutions were compared as gastrointestinal contrast media in three different psittacine species. (vin.com)
- Gastrointestinal contrast studies utilizing iohexol were of comparable diagnostic quality to those using the more routinely recommended barium sulfate. (vin.com)
- 4 Similar to mammals, barium sulfate suspension is contraindicated if gastrointestinal perforation is suspect. (vin.com)
- The purpose of this study was to evaluate gastrointestinal studies made with either barium sulfate suspension or iohexol solution in three psittacine species of differing body size. (vin.com)
- Lower GI (gastrointestinal) series (also called barium enema)- A procedure that examines the rectum, the large intestine, and the lower part of the small intestine. (beaumont.org)
Helicobacter1
- The mode of transmission of Helicobacter pylori gastrointestinal infections, infection is associated with infection is poorly characterized. (cdc.gov)
Symptom1
- The abnormality in gastrointestinal transit is considered as an unfathomable symptom. (springeropen.com)
Digestion1
- A highly digestible formula with balanced fibres, including prebiotics, to support healthy digestion and gastrointestinal transit. (royalcanin.com)
Small-bowel2
- 05). Alvimopan reversed codeine's effect on small bowel and colon (ascending colon and overall colonic transit). (elsevier.com)
- Conclusions: Alvimopan reverses codeine's inhibitory effect on small-bowel and colon transit and has potential for treatment of opiate bowel dysfunction. (elsevier.com)
Diarrhea1
- 2,5 The primary indications for a gastrointestinal contrast study in birds include regurgitation, vomiting or diarrhea, palpation of an abnormal crop or abdominal mass, or abnormal radiographic findings such as an obstructive bowel pattern, organomegaly or organ displacement. (vin.com)
Hematochezia1
- Upper gastrointestinal bleeding can be manifested with hematemesis, melena or hematochezia. (ghrnet.org)
Rats1
- Octopamine, but not ß-MPEA, delayed the gastrointestinal transit of a liquid test meal in awaken rats. (bvsalud.org)
Study2
- Interested in running a Gastrointestinal Transit study? (meliordiscovery.com)
- On three separate occasions, each bird underwent a complete gastrointestinal radiographic study. (vin.com)
Tolerance2
- To investigate whether healthy term infants, fed an infant formula containing hydrolyzed whey protein (HWP-F, hydrolyzed whey/intact casein =63/37), differ in growth, gastrointestinal tolerance and stool characteristics from those fed an infant formula containing intact whey protein (IWP-F, intact whey/intact casein =61/39) or breast milk. (mdpi.com)
- Gastrointestinal Tolerance of Chicory Inulin Products. (shiprockhigh.org)
Diet1
- ROYAL CANIN® Gastrointestinal low fat is a precisely formulated diet for dogs with conditions requiring a highly digestible, significantly fat restricted nutritional solution. (royalcanin.com)
Bowel transit2
- Instead, bowel transit is often measured with small probes called manometry. (medlineplus.gov)
- Dietary fibre has been shown to positively impact the composition of gut bacteria and exerts beneficial effects on bowel transit and total bacterial numbers. (togethermag.eu)
Stool transit1
- Patients are encouraged to eat foods high in fiber for one week before testing to cause more rapid stool transit. (aafp.org)
Incidence1
- Incidence of and risk factors for occupational injury among transit bus operators. (cdc.gov)
Digestive1
- Royal Canin Gastrointestinal High Fiber is a veterinary-exclusive dry dog food for dogs with long- or short-term digestive sensitivities. (southernagriculture.com)
Patients4
- Statistical evaluation of the data showed, however, that constipated patients had lower stool output and slower transit whether or not they had taken bran, and they responded less well to bran treatment than controls. (bmj.com)
- About one half of patients with gastrointestinal bleeding do not have an obvious source of the bleeding. (aafp.org)
- to assess risk factors for hepatic encephalopathy development in Egyptian patients with gastrointestinal bleeding. (ghrnet.org)
- 120 cirrhotic patients with upper gastrointestinal bleeding were randomly assigned into: (group I) patients who complicated with hepatic encephalopathy (n = 60) versus (group II) patients not complicated with hepatic encephalopathy (n = 60). (ghrnet.org)
Mice1
- The Morphine group displayed a reduction in percent transit of the bolus compared to the vehicle treated mice. (meliordiscovery.com)
Effects1
- Given the alteration in the upper gastrointestinal anatomy, certain side effects of bariatric surgery can be expected and ameliorated through patient education and postoperative treatment. (medscape.com)
Food3
- Royal Canin Gastrointestinal Low Fat Dry Dog Food is a palatable, digestible low fat dog food formulated for dogs that may have difficulties digesting or tolerating fat. (chewy.com)
- Finding this very specialized food is very difficult but Southern Agriculture has been amazing in carrying and shipping the Royal Canin Gastrointestinal High Fiber dog food. (southernagriculture.com)
- The group had consumed food prepared by a restaurant on the Gold Coast before transit. (who.int)
Systemic1
- 6-11 This concept is based on the assumption that the gastrointestinal mucosa receives its share of increased systemic and regional oxygen delivery. (asahq.org)