A prospective randomized study of megestrol acetate and ibuprofen in gastrointestinal cancer patients with weight loss. (1/1704)
The use of megestrol acetate in the treatment of weight loss in gastrointestinal cancer patients has been disappointing. The aim of the present study was to compare the combination of megestrol acetate and placebo with megestrol acetate and ibuprofen in the treatment of weight loss in such patients. At baseline, 4-6 weeks and 12 weeks, patients underwent measurements of anthropometry, concentrations of albumin and C-reactive protein and assessment of appetite, performance status and quality of life using EuroQol-EQ-5D and EORTC QLQ-C30. Thirty-eight and 35 patients (median weight loss 18%) were randomized to megestrol acetate/placebo or megestrol acetate/ibuprofen, respectively, for 12 weeks. Forty-six (63%) of patients failed to complete the 12-week assessment. Of those evaluable at 12 weeks, there was a decrease in weight (median 2.8 kg) in the megestrol acetate/placebo group compared with an increase (median 2.3 kg) in the megestrol acetate/ibuprofen group (P<0.001). There was also an improvement in the EuroQol-EQ-5D quality of life scores of the latter group (P<0.05). The combination of megestrol acetate/ibuprofen appeared to reverse weight loss and appeared to improve quality of life in patients with advanced gastrointestinal cancer. Further trials of this novel regimen in weight-losing patients with hormone-insensitive cancers are warranted. (+info)Predicting delayed anxiety and depression in patients with gastrointestinal cancer. (2/1704)
The aim of this study was to examine the possibility of predicting anxiety and depression 6 months after a cancer diagnosis on the basis of measures of anxiety, depression, coping and subjective distress associated with the diagnosis and to explore the possibility of identifying individual patients with high levels of delayed anxiety and depression associated with the diagnosis. A consecutive series of 159 patients with gastrointestinal cancer were interviewed in connection with the diagnosis, 3 months (non-cured patients only) and 6 months later. The interviews utilized structured questionnaires assessing anxiety and depression [Hospital Anxiety and Depression (HAD) scale], coping [Mental Adjustment to Cancer (MAC) scale] and subjective distress [Impact of Event (IES) scale]. Patient anxiety and depression close to the diagnosis were found to explain approximately 35% of the variance in anxiety and depression that was found 6 months later. The addition of coping and subjective distress measures did little to improve that prediction. A model using (standardized) cut-off scores of moderate to high anxiety, depression (HAD) and intrusive thoughts (IES subscale) close to the diagnosis to identify patients at risk for delayed anxiety and depression achieved a sensitivity of 75% and a specificity of 98%. Levels of anxiety and depression at diagnosis predicted a similar status 6 months later. The results also indicated that the HAD scale in combination with the IES intrusion subscale may be used as a tool for detecting patients at risk of delayed anxiety and depression. (+info)Management and outcome of patients undergoing surgery after acute upper gastrointestinal haemorrhage. Steering Group for the National Audit of Acute Upper Gastrointestinal Haemorrhage. (3/1704)
Most patients with acute upper gastrointestinal haemorrhage are managed conservatively or with endoscopic intervention but some ultimately require surgery to arrest the haemorrhage. We have conducted a population-based multicentre prospective observational study of management and outcomes. This paper concerns the subgroup of 307 patients who had an operation because of continued or recurrent haemorrhage or high risk of further bleeding. The principal diagnostic group was those with peptic ulcer. Of 2071 patients with peptic ulcer presenting with acute haemorrhage, 251 (12%) had an operative intervention with a mortality of 24%. In the non-operative group mortality was 10%. The operative intervention rate increased with risk score, ranging from 0% in the lowest risk categories to 38% in the highest. Much of the discrepancy between operative and non-operative mortality was explainable by case mix; however, for high-risk cases mortality was significantly higher in the operated group. In 78% of patients who underwent an operation for bleeding peptic ulcer there had been no previous attempt at endoscopic haemostasis. For patients admitted to surgical units, the operative intervention rate was about four times higher than for those admitted under medical teams. In patients with acute upper gastrointestinal haemorrhage operative intervention is infrequent and largely confined to the highest-risk patients. The continuing high mortality in surgically treated patients is therefore to be expected. The reasons for the low use of endoscopic treatment before surgery are not revealed by this study, but wider use of such treatments might further reduce the operative intervention rate. Physicians and surgeons have not yet reached consensus on who needs surgery and when. (+info)Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors. (4/1704)
The c-kit gene encodes a transmembrane receptor kinase (KIT) which is expressed in the majority of human gastrointestinal stromal tumors (GISTs), a subtype of gastrointestinal mesenchymal neoplasms. A previous study identified mutations in the juxtamembrane (JM) domain of c-kit in five of six GISTs (Science 279: 577, 1998). To better define the frequency and spectrum of c-kit gene mutations in mesenchymal neoplasms of the GI tract that had been characterized for KIT protein expression, we examined archived tissue samples for mutations in the JM domain by PCR amplification and DNA sequencing. c-kit JM domain mutations were found in nine of 56 mesenchymal tumors (46 GISTs, eight leiomyomas, two leiomyosarcomas) and occurred exclusively in GISTs (21%). Seven of the nine mutations consisted of intragenic deletions of one to 19 codons. There was one insertion mutation that added 12 codons and one missense mutation (Val560Asp). None of the mutations disrupted the downstream reading frame of the gene. The single missense mutation (Val560Asp) is very similar to the only other missense mutation reported in GISTs (Val599Asp). Of the 46 GISTs, 43 were strongly positive for KIT protein expression and negative for diffuse expression of desmin. Neither KIT expression nor gene mutations were found in gastrointestinal leiomyomas or leiomyosarcomas. We conclude that mutation of the c-kit JM domain does not occur in gastrointestinal mesenchymal neoplasms with well developed-smooth muscle differentiation, and is restricted to GISTs. However, since these mutations are only found in a minority of GISTs, further investigation into the mechanisms of c-kit gene activation in this group of neoplasms is warranted. (+info)Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice. (5/1704)
An3 1 KAL I MutL homologue 1 (MLH1) is a member of the family of proteins required for DNA mismatch repair. Germ-line mutations in MLH1 lead to the cancer susceptibility syndrome hereditary nonpolyposis colorectal cancer (HNPCC). We generated mice carrying a null mutation in the Mlh1 gene. We showed that mice heterozygous and homozygous for the Mlh1 gene are predisposed to developing tumors of the gastrointestinal (GI) tract, lymphomas, and a number of other tumor types. We also examined the role of adenomatous polyposis coli gene (Apc) gene mutations in the GI tumors of Mlh1 mutant mice by different methods and showed that the GI tumors in Mlh1 mice express little or no adenomatous polyposis coli protein. When an Apc gene mutation was bred into the Mlh1 mutant mice, the GI tumor incidence increased 40-100-fold. The wild-type Apc allele in these tumors was found to contain mutations. Together, these results show that we have developed two mouse models for human HNPCC and that the mechanisms of tumor development in the GI tract of these mice involve loss of Apc gene function in a manner very similar to that seen in the GI tumors of HNPCC. (+info)Review article: current status of gastrointestinal carcinoids. (6/1704)
Carcinoid tumours are enigmatic, slow growing malignancies which occur most frequently (74%) in the gastrointestinal tract. In recent years, it has become apparent that the term 'carcinoid' represents a wide spectrum of different neoplasms originating from a variety of different neuroendocrine cell types. Carcinoid lesions are usually identified histologically by their affinity for silver salts, by general neuroendocrine markers, or more specifically by immunocytochemistry using antibodies against their specific cellular products. Within the gut, the most frequent sites are the small bowel (29%), the appendix (19%) and rectum (13%). Clinical manifestations are often vague or absent. Nevertheless, in approximately 10% of patients the tumours secrete bioactive mediators which may engender various elements of characteristic carcinoid syndrome. In many instances the neoplasms are detected incidentally at the time of surgery for other gastrointestinal disorders. The tendency for metastatic spread correlates with tumour size, and is substantially higher in lesions larger than 2.0 cm. An association with noncarcinoid neoplasms is ascribed in 8-17% of lesions. Treatment consists of radical surgical excision of the tumour, although gastric (type I and II) and rectal carcinoids may be managed with local excision. Overall 5-year survival is excellent for carcinoids of the appendix (86%) and rectum (72%), whereas small intestinal (55%), gastric (49%) and colonic carcinoids (42%) exhibit a far worse prognosis. (+info)Treatment of upper abdominal malignancies with organ cluster procedures. (7/1704)
Upper abdominal exenteration for upper abdominal malignancies was carried out in 15 patients with removal of the liver, spleen, pancreas, duodendum, all or part of the stomach, proximal jejunum and ascending and transverse colon. Organ replacement was with the liver, pancreas and duodenum plus, in some cases, a short segment of jejunum. Eleven of the 15 patients survived for more than 4 months; 2 died, after 61/2 and 10 months, of recurrent tumor. Of the 9 patients who are surviving after 61/2 to 14 months, recurrent tumor is suspected in only 1 and proven in none. Four patients with sarcomas and carcinoid tumors (2 each) have had no recurrences. The other 5 survivors had duct cell cancers (3 examples), a cholangiocarcinoma (1 example), and a hepatoma (1 example). The experience so far supports further cautious trials with this drastic cancer operation. (+info)Enteral nutritional supplementation with key nutrients in patients with critical illness and cancer: a meta-analysis of randomized controlled clinical trials. (8/1704)
OBJECTIVE: To conduct a meta-analysis of 11 randomized controlled trials comparing enteral nutritional support supplemented with key nutrients versus standard enteral nutritional support to determine effects on morbidity and mortality rates and hospital stay. BACKGROUND DATA: Recent studies have shown that malnutrition occurs in up to 30% of patients undergoing gastrointestinal surgery, resulting in an increased risk of postoperative complications and death. With the realization that key nutrients can modulate inflammatory, metabolic, and immune processes, enteral nutritional regimens (supplemented with large amounts of key nutrients) have been developed for clinical use. METHODS: Eleven prospective, randomized controlled trials evaluating 1009 patients treated with combinations of key nutrients (Impact, Immun-Aid) were evaluated. Outcome measures examined were the incidences of pneumonia, infectious complications, and death, and length of hospital stay. Meta-analyses were undertaken to obtain the odds ratio and 95% confidence interval for incidences of infectious complications, pneumonia, and death, and the weighted mean difference and 95% confidence interval for length of hospital stay. RESULTS: The provision of nutritional support supplemented with key nutrients to patients with critical illness resulted in a decrease in infectious complications when compared with patients receiving standard nutritional support and a significant reduction in overall hospital stay. Similar results were documented in patients with gastrointestinal cancer. However, there were no differences between patient groups for either pneumonia or death. CONCLUSIONS: This meta-analysis has demonstrated that nutritional support supplemented with key nutrients results in a significant reduction in the risk of developing infectious complications and reduces the overall hospital stay in patients with critical illness and in patients with gastrointestinal cancer. However, there is no effect on death. These data have important implications for the management of such patients. (+info)
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Pancreatic mucinous cystic neoplasm
Gastrointestinal Endoscopy. 67 (4): 636-42. doi:10.1016/j.gie.2007.09.038. PMID 18262182. Oh, HC; Seo, DW; Song, TJ; Moon, SH; ... Pancreatic mucinous cystic neoplasm (MCN) is a type of cystic lesion that occurs in the pancreas. Amongst individuals ... Intraductal papillary mucinous neoplasm Pancreatic serous cystadenoma Elta, GH; Enestvedt, BK; Sauer, BG; Lennon, AM (April ... Where possible, surgical resection of mucinous cystic neoplasms is preferable. In individuals who are eligible to undergo ...
Intraductal papillary mucinous neoplasm
World Journal of Gastrointestinal Surgery. 2 (10): 342-6. doi:10.4240/wjgs.v2.i10.342. ISSN 1948-9366. PMC 2999210. PMID ... Pancreatic serous cystadenoma Solid pseudopapillary neoplasm "Intraductal Papillary Mucinous Neoplasms of the Pancreas". Johns ... Intraductal papillary mucinous neoplasm (IPMN) is a type of tumor that can occur within the cells of the pancreatic duct. IPMN ... Campbell, NM; Katz, SS; Escalon, JG; Do, RK (March 2015). "Imaging patterns of intraductal papillary mucinous neoplasms of the ...
Endoscopic submucosal dissection
Application of endoscopic resection (ER) to gastrointestinal (GI) neoplasms is limited to lesions with no risk of nodal ... The resected size and shape can be controlled, en bloc resection is possible even in a large neoplasm, and neoplasms with ... Kakushima, Naomi; Fujishiro, Mitsuhiro (2008). "Endoscopic submucosal dissection for gastrointestinal neoplasms". World Journal ... So this technique can be applied to the resection of complex neoplasms such as large neoplasms, ulcerative non-lifting ...
Anaerobic infection
... recent gastrointestinal, obstetric, or gynecologic surgery; malignant neoplasms intestinal obstruction; decubitus ulcers; ... colonize the lower gastrointestinal tract, they can contaminate compound lower extremities fractures.[citation needed] Septic ... is often associated with a gastrointestinal source, pigmented Prevotella and Porphyromonas spp. and Fusobacterium spp.with ... Perforated appendicitis, diverticulitis, inflammatory bowel disease with perforation and gastrointestinal surgery are often ...
Neoplasm
Bernstein C, Bernstein H, Payne CM, Dvorak K, Garewal H (February 2008). "Field defects in progression to gastrointestinal ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term neoplasm is a synonym of tumor. Neoplasia denotes the process of the formation of neoplasms/tumors, and the process is ... The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that ...
Indolent T cell lymphoproliferative disorder of the gastrointestinal tract
Matutes E (May 2018). "The 2017 WHO update on mature T- and natural killer (NK) cell neoplasms". International Journal of ... Indolent T cell lymphoproliferative disorder of the gastrointestinal tract or Indolent T cell lymphoproliferative disorder of ... Weindorf SC, Smith LB, Owens SR (November 2018). "Update on Gastrointestinal Lymphomas". Archives of Pathology & Laboratory ... Cahu X, Constantinescu SN (December 2015). "Oncogenic Drivers in Myeloproliferative Neoplasms: From JAK2 to Calreticulin ...
Neuroendocrine tumor
G1 and G2 neuroendocrine neoplasms are called neuroendocrine tumors (NETs) - formerly called carcinoid tumours. G3 neoplasms ... Most gastrointestinal carcinoid tumors tend not to respond to chemotherapy agents, showing 10 to 20% response rates that are ... Although there are many kinds of NETs, they are treated as a group of tissue because the cells of these neoplasms share common ... Gastrointestinal Carcinoid Tumors Treatment cancer.gov Archived 2011-06-27 at the Wayback Machine National Cancer Institute. ...
Anthramycin
... has been shown particularly effective against sarcomas, lymphomas, and gastrointestinal neoplasms.[citation needed ...
Small intestine cancer
It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer (stomach cancer) and colorectal ... Malignant Neoplasms of the Small Intestine. eMedicine.com. URL: http://www.emedicine.com/MED/topic2651.htm. Accessed on: June 2 ... Five-year survival rates are 65%. Subtypes of small intestine cancer include: Adenocarcinoma Gastrointestinal stromal tumor ... Articles with short description, Short description is different from Wikidata, Gastrointestinal cancer). ...
Gastrointestinal stromal tumor
... s (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in ... many non-epithelial tumors of the gastrointestinal tract were called "gastrointestinal stromal tumors". Histopathologists were ... KIT-p.D419del (exon 8) - A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic ... GISTs are tumors of connective tissue, i.e. sarcomas; unlike most gastrointestinal tumors, they are nonepithelial. About 70% ...
MLH1
"Clinicopathological relevance of the association between gastrointestinal and sebaceous neoplasms: the Muir-Torre syndrome". ... Bernstein C, Bernstein H (2015). "Epigenetic reduction of DNA repair in progression to gastrointestinal cancer". World J ...
Pancreatic serous cystadenoma
... mixed serous-endocrine neoplasm, and VHL-associated serous cystic neoplasm. This latter classification scheme is useful because ... Journal of Gastrointestinal Surgery. 11 (7): 820-826. doi:10.1007/s11605-007-0157-4. PMID 17440789. S2CID 32023143. Elta GH, ... Serous cystic neoplasms that have spread ("metastasized") to another organ are considered malignant and are designated "serous ... In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and ...
Muir-Torre syndrome
Along with neoplasms of the sebaceous gland, this patient developed cerebral neoplasms, characteristic of Turcot syndrome. ... Gastrointestinal and genitourinary cancers are the most common internal malignancies. Colorectal cancer is the most common ... Age of onset of first sebaceous neoplasm: 2 = 2 points. Personal history of Lynch related cancers: No = 0 points, Yes = 1 point ... 2014). "A clinical scoring system to identify patients with sebaceous neoplasms at risk for the Muir-Torre variant of Lynch ...
Human feces
... ulcerative colitis and neoplasms (cancer). Also, feces may be analyzed for any fecal occult blood, which is indicative of a ... combines with gastrointestinal bleeding from any source (black stool). It can also suggest a carcinoma of the ampulla of Vater ... which will result in gastrointestinal bleeding and biliary obstruction, resulting in silver stool. Feces can be green due to ... gastrointestinal bleeding. A quick test for fecal contamination of water sources or soil is a check for the presence of E. coli ...
Retroperitoneal space
The most common type is a sarcoma followed by lymphoma, extragonadal germ cell tumor, and Gastrointestinal stromal tumor/GIST. ... Retroperitoneal fibrosis Retroperitoneal lymph node dissection It is also possible to have a neoplasm in this area, more ... commonly a metastasis; or very rarely a primary neoplasm. ...
MedDRA
Neoplasms benign, malignant and unspecified (incl cysts and polyps); Nervous system disorders; Pregnancy, puerperium and ... Gastrointestinal disorders; General disorders and administration site conditions; Hepatobiliary disorders; Immune system ...
Siamese cat
The majority of deaths were caused by neoplasms, mainly mammary tumors. The Siamese also has a higher rate of morbidity. They ... are at higher risk of neoplastic and gastrointestinal problems, but have a lower risk of feline lower urinary tract disease. ...
Toxicodynamics
Neoplasms occurring in epithelial tissue such as the liver, gastrointestinal tract, and the pancreas have been linked to ...
Attenuated familial adenomatous polyposis
Gastrointestinal cancer, Hereditary cancers, All stub articles, Neoplasm stubs). ...
Hamartoma
When seen on upper gastrointestinal series, a pancreatic rest may appear to be a submucosal mass or gastric neoplasm. Most are ... A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an ... Case report: ectopic pancreatic rest in the proximal stomach mimicking gastric neoplasms. Clin Radiol. 2007 Jun;62(6):600-2. ... the definition of hamartoma versus benign neoplasm is often unclear, since both lesions can be clonal. Lesions such as adenomas ...
David B. Adams
... , M.D. (born 1950) is Professor of Surgery, Chief, Division of Gastrointestinal and Laparoscopic Surgery and Co- ... Ellis, C. T.; Barbour, J. R.; Shary, T. M.; Adams, D. B. (2010). "Pancreatic cyst: Pseudocyst or neoplasm? Pitfalls in ... Theruvath, T. P.; Morgan, K. A.; Adams, D. B. (2010). "Mucinous cystic neoplasms of the pancreas: How much preoperative ... Association American College of Surgeons American Society for Gastrointestinal Endoscopy Society of American Gastrointestinal ...
Large intestine
The gastrointestinal tract is derived from these layers. One variation on the normal anatomy of the colon occurs when extra ... and left-sided colorectal neoplasms after colonoscopy: population-based study". J Natl Cancer Inst. 102 (2): 89-95. doi:10.1093 ... The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system ... The descending colon is also called the distal gut, as it is further along the gastrointestinal tract than the proximal gut. ...
Tyrosine kinase
Gastrointestinal stromal tumors consist of a cluster of mesenchymal neoplasms that are formed from precursors to cells that ... Gastrointestinal stromal tumors (GIST) are mesenchymal tumors that affect the gastrointestinal tract. Treatment options have ... Therapy with imatinib can inhibit the non-normal cell signaling mechanisms in gastrointestinal stromal tumors. This results in ... There are no effective means of treatment for advanced gastrointestinal stromal tumors, but that STI571 represents an effective ...
Carney's triad
Carney triad (CT) is characterized by the coexistence of three types of neoplasms, mainly in young women, including gastric ... A third condition, the Carney-Stratakis syndrome (CSS), describes the dyad of hereditary gastrointestinal stromal tumor (GIST) ... The Carney complex is a distinct entity, characterized by myxomatous neoplasms (cardiac, endocrine, cutaneous and neural), and ... Subsequent advances in molecular biology have led to the current terminology of gastrointestinal stromal tumors (GISTs). ...
Mesoblastic nephroma
... of all childhood renal neoplasms. This neoplasm is generally non-aggressive and amenable to surgical removal. However, a ... 2 with gastrointestinal anomalies, 1 with hydrocephalus, and 1 with the Beckwith-Wiedemann syndrome. The vast majority of ... It shows a mixture of the classic and cellular types in different areas of the neoplasm. A study conducted in 1998 found that ... Congenital mesoblastic nephroma, while rare, is the most common kidney neoplasm diagnosed in the first three months of life and ...
Intraepithelial neoplasia
Hackeng WM, Hruban RH, Offerhaus GJ, Brosens LA (2016). "Surgical and molecular pathology of pancreatic neoplasms". Diagn ... 2000). "The Vienna classification of gastrointestinal epithelial neoplasia". Gut. 47 (2): 251-5. doi:10.1136/gut.47.2.251. PMC ...
MALT lymphoma
2012). Handbook of Gastrointestinal Cancer (2 ed.). Chicester: John Wiley and Sons Ltd. pp. 243-244. ISBN 978-0-470-65624-2. ... ISBN 0-7817-5007-5. Frequency of lymphoid neoplasms. (Source: Modified from WHO Blue Book on Tumour of Hematopoietic and ... Gastrointestinal cancer, Lymphoma, Infectious causes of cancer). ...
Neurofibromin 1
... gastrointestinal stromal tumors (GIST), Watson syndrome, astrocytic neoplasms, phaeochromocytomas and breast cancer. No ... which develops myeloproliferative neoplasms similar to those found in NF1 juvenile myelomonocytic leukemia/JMML) were used to ... an oral selective MEK inhibitor used previously in several advanced adult neoplasms. The children enrolled in the study ...
Endoscope
Edmonson JM (March 1991). "History of the instruments for gastrointestinal endoscopy". Gastrointestinal Endoscopy. 37 (2 Suppl ... Small intestine: small intestine neoplasms, smooth muscle tumors, sarcomas, polyps, lymphomas, inflammation, etc. Large ... Whilst there are regions of the body that will always require flexible endoscopes (principally the gastrointestinal tract), the ... Health care workers can use endoscopes to review the following body parts: The gastrointestinal tract: Esophagus: chronic ...
Pseudomyxoma peritonei
For example, neoplasms characterized by high-grade features, invasive glands and or signet ring cells, are termed ... Harmon RL, Sugarbaker PH (February 2005). "Prognostic indicators in peritoneal carcinomatosis from gastrointestinal cancer". ... Young RH (May 2004). "Pseudomyxoma peritonei and selected other aspects of the spread of appendiceal neoplasms". Seminars in ... ISBN 978-0-323-35909-2. Sugarbaker PH (January 2006). "New standard of care for appendiceal epithelial neoplasms and ...
Appendix cancer
Gastrointestinal stromal tumors are rare tumors with malignant potential. Primary lymphomas can occur in the appendix. Breast ... Mucinous cystadenoma is an obsolete term for appendiceal mucinous neoplasm. Small carcinoids (. ...
List of diseases (C)
Carrington syndrome Cartilage hair hypoplasia like syndrome Cartilage-hair hypoplasia Cartilaginous neoplasms Cartwright-Nelson ... Congenital erythropoietic porphyria Congenital facial diplegia Congenital fiber type disproportion Congenital gastrointestinal ... hypoxia Cerebral malformations hypertrichosis claw hands Cerebral palsy Cerebral thrombosis Cerebral ventricle neoplasms ... Choriocarcinoma Chorioretinitis Chorioretinopathy dominant form microcephaly Choroid plexus cyst Choroid plexus neoplasms ...
Index of biochemistry articles
... neoplasm protein - Nernst equation - nerve - nerve growth factor - nerve growth factor receptor - nerve tissue protein - nerve ... gastrointestinal hormone receptor - gastrula - gel electrophoresis - gene - gene expression - gene pool - gene regulatory ...
Primary effusion lymphoma
Gastrointestinal track lesions often occur as multiple lymphoid polyps in the large intestine. At diagnosis, more than 50% of ... This lymphoma also belongs to a group of lymphoid neoplasms with plasmablastic differentiation that involve malignant ... The extracavitary tumors may develop in lymph nodes, bone, bone marrow, the gastrointestinal tract, skin, spleen, liver, lungs ... Individuals with extracavitary PEL present with lesions in the lung, central nervous system, gastrointestinal tract, and/or ...
Dendritic cell
Blastic plasmacytoid dendritic cell neoplasm is a rare type of myeloid cancer in which malignant pDCs infiltrate the skin, bone ... gastrointestinal tract, bone, sinuses, ears, and/or testes. The disease may also present as a pDC leukemia, i.e. increased ... Wang S, Wang X, Liu M, Bai O (April 2018). "Blastic plasmacytoid dendritic cell neoplasm: update on therapy especially novel ... Blastic plasmacytoid dendritic cell neoplasm has a high rate of recurrence following initial treatments with various ...
Low-grade myofibroblastic sarcoma
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... the thin layer of tissue lying just below the mucous membranes that line passageways such as the gastrointestinal, respiratory ...
Rectal discharge
Rare neoplasms at this site that can give rise to discharge include Paget's disease (which is possibly a type of adenocarcinoma ... Vernava AM, Moore BA, Longo WE, Johnson FE (1997). "Lower gastrointestinal bleeding". Dis. Colon Rectum. 40 (7): 846-58. doi: ...
Cancer
They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often ... Rates of gastrointestinal cancers are increased in people with Crohn's disease and ulcerative colitis, due to chronic ... In the general population, NSAIDs reduce the risk of colorectal cancer; however, due to cardiovascular and gastrointestinal ... World Journal of Gastrointestinal Oncology. 5 (3): 43-49. doi:10.4251/wjgo.v5.i3.43. PMC 3648662. PMID 23671730. Narayanan L, ...
Chronic lymphocytic leukemia
Gastrointestinal (GI) involvement can rarely occur with chronic lymphocytic leukemia. Some of the reported manifestations ... Hairy cell leukemia is also a neoplasm of B lymphocytes, but the neoplastic cells have a distinct morphology under the ... ISBN 978-0-7817-5007-3. Frequency of lymphoid neoplasms. (Source: Modified from WHO Blue Book on Tumour of Hematopoietic and ... Choi SM, O'Malley DP (December 2018). "Diagnostically relevant updates to the 2017 WHO classification of lymphoid neoplasms". ...
Adrenal medulla
Neoplasms include: Pheochromocytoma (most common), a catecholamine-secreting tumor of the adrenal medulla Neuroblastoma, a ... blood vessel constriction in the skin and gastrointestinal tract, smooth muscle (bronchiole and capillary) dilation, and ...
Periodontal disease
... diarrhoea and gastrointestinal disturbances. There is currently low-quality evidence suggesting if adjunctive systemic ... induced Genetic/developmental disorders Specific infections Inflammatory and immune conditions Reactive processes Neoplasms ...
Phenoxybenzamine
Due to its 5-HT2A receptor antagonism, phenoxybenzamine is useful in the treatment of carcinoid tumor, a neoplasm that secretes ... 206-. ISBN 978-0-08-054111-2. Timothy S. Gaginella; James J. Galligan (25 July 1995). Serotonin and Gastrointestinal Function. ...
Radiation therapy
Radiation enteropathy The gastrointestinal tract can be damaged following abdominal and pelvic radiotherapy. Atrophy, fibrosis ... Hypopituitarism commonly develops after radiation therapy for sellar and parasellar neoplasms, extrasellar brain tumours, head ...
Lower gastrointestinal bleeding
H7 Shigella Salmonella Campylobacter jejuni Hemorrhoids Neoplasm - such as colorectal cancer Angiodysplasia Bleeding from a ... Lower gastrointestinal bleeding, commonly abbreviated LGIB, is any form of gastrointestinal bleeding in the lower ... LGIB accounts for 30-40% of all gastrointestinal bleeding and is less common than upper gastrointestinal bleeding (UGIB). It is ... A lower gastrointestinal bleed is defined as bleeding originating distal to the ileocecal valve which includes the colon, ...
List of skin conditions
... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... "Paraneoplastic dermatological manifestation of gastrointestinal malignancies". World J. Gastroenterol. 15 (35): 4372-79. doi: ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ... neoplasms invading or aberrantly present in the dermis. Acquired progressive lymphangioma (benign lymphangioendothelioma) Acral ...
Plasmacytoid dendritic cell
Wang S, Wang X, Liu M, Bai O (April 2018). "Blastic plasmacytoid dendritic cell neoplasm: update on therapy especially novel ... gastrointestinal tract, bone, sinuses, ears, and/or testes. The disease may also present as a pDC leukemia, i.e. increased ... Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare type of myeloid cancer in which malignant pDCs infiltrate the ... pDCs that undergo malignant transformation cause a rare hematologic disorder, blastic plasmacytoid dendritic cell neoplasm. In ...
Malignancy
This includes bone marrow suppression, gastrointestinal problems and alopecia. Some side effects are specific to the anticancer ... Uses of "malignant" in oncology include: Malignancy, malignant neoplasm and malignant tumor are synonymous with cancer ...
Nicolaus Copernicus University Ludwik Rydygier Collegium Medicum in Bydgoszcz
In the 2000s, scientific research conducted by the institution focused on various domains: neoplasm, injury and their ... Surgery Department of Urology and Andrology Cell and Tissue Bank Laboratory for Pediatric Endoscopy and Gastrointestinal ... Neoplasms and Tuberculosis Department of Infectious Diseases and Hepatology Department of Dermatology and Venereology ...
Iodine-131
It can also cause sialadenitis (an inflammation of the salivary gland), gastrointestinal disturbances, allergic reactions and ... "Malignant and benign neoplasms of the thyroid in patients treated for hyperthyroidism: a report of the cooperative ...
Ollier disease
While chondrosarcoma is the most common form of a secondary malignant bone neoplasm found in cases of Ollier disease, other ... like chondrosarcomas but also much more aggressive tumors such as acute lymphocytic leukemia and gastrointestinal and ovarian ... Early detection and consistent and repeated monitoring is important in order to prevent and treat any potential bone neoplasms ... Clinical and radiological evaluations are conducted in order to detect the presence of bone neoplasms or lesions typically ...
Brain metastasis
Neoplasm Metastasis Cancer Brain tumor Tse V (10 November 2009). "Brain Metastasis". Medscape. Retrieved 13 January 2010. " ... Gastrointestinal cancers, especially colorectal and pancreatic carcinoma, 3% Lymphoma, 1% Lung cancer and melanoma are most ... Percy AK, Elveback LR, Okazaki H, Kurland LT (January 1972). "Neoplasms of the central nervous system. Epidemiologic ... the national survey of intracranial neoplasms". Neurology. 35 (2): 219-26. doi:10.1212/WNL.35.2.219. PMID 3969210. S2CID ...
Tumors of the hematopoietic and lymphoid tissues
CEBPA mutation Myeloid neoplasms with germline DDX41 mutation Myeloid neoplasms with germline RUNX1 mutation Myeloid neoplasms ... NOS Indolent T-cell lymphoproliferative disorder of the gastrointestinal tract Hepatosplenic T-cell lymphoma Subcutaneous ... neoplasms with PDGFRA rearrangement Myeloid/lymphoid neoplasms with PDGFRB rearrangement Myeloid/lymphoid neoplasms with FGFR1 ... NOS Lymphoid neoplasms Precursor lymphoid neoplasms B-lymphoblastic leukaemia/lymphoma, NOS B-lymphoblastic leukaemia/lymphoma ...
Serous cystadenocarcinoma
Journal of Gastrointestinal Surgery. 13 (10): 1864-1868. doi:10.1007/s11605-009-0926-3. PMC 2759006. PMID 19459016. Friebe V, ... Neoplasm stubs). ...
Anal cancer
... is a cancer which arises from the anus, the distal opening of the gastrointestinal tract. Symptoms may include ... Chemotherapy commonly used is similar to other squamous cell epithelial neoplasms, such as platinum analogues, anthracyclines ... and Colostomy Failure in US Gastrointestinal Intergroup RTOG 98-11 Phase 3 Trial. Int J Radiation Oncol Biol Phys, 2013, Vol. ... Gastrointestinal cancer, Papillomavirus-associated diseases, Infectious causes of cancer, Wikipedia medicine articles ready to ...
Proton therapy
"TREATING GASTROINTESTINAL MALIGNANCY WITH PROTON THERAPY". IBA White Paper. September 2016. Tae Hyung Kim (2020). "Proton beam ... Two prominent examples are pediatric neoplasms (such as medulloblastoma) and prostate cancer. Irreversible long-term side ... Indeed, the largest study to date showed that IMRT compared with proton therapy was associated with less gastrointestinal ... gastrointestinal and bladder side effects. Proton therapy for eye tumors is a special case since this treatment requires only ...
O6-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine...
In this study, we examined the MGMT and GLUT2 status in gastrointestinal neuroendocrine neoplasm (NEN). We studied 84 NEN cases ... 33 foregut and 37 hindgut GI-NETs and 14 gastrointestinal neuroendocrine carcinomas (GI-NECs). In GI-NETs, MGMT scores of ≥2 ... and gastrointestinal (GI-NET) neuroendocrine tumors but its therapeutic efficacy is relatively low in GI-NETs. Therefore, it ... In this study, we examined the MGMT and GLUT2 status in gastrointestinal neuroendocrine neoplasm (NEN). We studied 84 NEN cases ...
Lower Gastrointestinal Bleeding: Practice Essentials, Background, Anatomy
... of episodes of gastrointestinal (GI) hemorrhage, with an annual incidence of about 20-27 cases per 100,000 population in ... Neoplasm. Neoplastic bleeding can be from a polyp or carcinoma. Colon cancer is the predominant cause of neoplastic bleeding ... Lower gastrointestinal bleeding (LGIB) accounts for approximately 20%-33% of episodes of gastrointestinal (GI) hemorrhage, with ... Table 1. Common Causes of Lower Gastrointestinal Bleeding in Adults. *Table 2. Common Causes of Lower Gastrointestinal Bleeding ...
Pediatric Gastrointestinal Neoplasms: Background, Esophageal Neoplasms, Gastric Neoplasms
Primary GI neoplasms in children are rare entities. In 1960, the incidence of GI malignancies arising from the bowel was ... encoded search term (Pediatric Gastrointestinal Neoplasms) and Pediatric Gastrointestinal Neoplasms What to Read Next on ... Pediatric Gastrointestinal Neoplasms Updated: May 31, 2022 * Author: Nathaniel Koo, MD; Chief Editor: Max J Coppes, MD, PhD, ... Primary gastrointestinal (GI) neoplasms in children are rare. [1] In 1960, the incidence of GI malignancies arising from the ...
Results of search for 'su:{Gastrointestinal neoplasms.}' › WHO HQ Library catalog
Results of search for su:{Gastrointestinal neoplasms.} Refine your search. *. Availability. * Limit to currently available ... Gastrointestinal cancer / edited by Jerome J. DeCosse and Paul Sherlock. 1, . by DeCosse, Jerome J , Sherlock, Paul. ... Combined modality therapy of gastrointestinal tract cancer / P. Schlag, P. Hohenberger, U. Metzger (eds.) by Schlag, Peter , ... Nutrition in gastrointestinal disease / edited by Robert C. Kurtz. by Kurtz, Robert C. ...
Find a Doctor in Your Area: Search Results - Sharecare
Simultaneous Triple Primary Neoplasms in the
Gastrointestinal Tract: A Rare Case Report
| Biomedres
Multiple primary neoplasms (MPNs) were not recognized until the 1890s [1]. ... Simultaneous Triple Primary Neoplasms in the Gastrointestinal Tract: A Rare Case Report Volume 14 - Issue 2 ... Keywords: Case Report; Multiple Primary Neoplasms; Primary Colon Cancer. Abbrevations: MPNs: Multiple Primary Neoplasms; CT: ... Background: Multiple primary neoplasms (MPNs) are of rare occurrence. The majority of MPNs are double primary neoplasms while ...
Gastrointestinal Complications (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf
Get detailed information about gastrointestinal complications and ways to manage them in this clinician summary. ... Gastrointestinal complications (e.g., constipation, bowel obstruction, diarrhea) can be tumor or treatment related and are ... This agent inhibits the release of several gastrointestinal hormones and reduces gastrointestinal secretions.[22,23][Level of ... Symptoms of gastrointestinal GVHD include nausea and vomiting, severe abdominal pain and cramping, and watery, green diarrhea.[ ...
Nature Reviews Clinical Oncology
Nature Reviews Clinical Oncology
Gastrointestinal stromal tumor: MedlinePlus Genetics
... is a type of tumor that occurs in the gastrointestinal tract, most commonly in the stomach or small intestine. Explore symptoms ... Gastrointestinal stromal neoplasm. *Gastrointestinal stromal sarcoma. *GIST. Additional Information & Resources. Genetic ... A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs in the gastrointestinal tract, most commonly in the ... Sometimes, tumors cause bleeding into the gastrointestinal tract, which may lead to low red blood cell counts (anemia. ) and, ...
Systematic study of novel lncRNAs in different gastrointestinal cancer cells
... which could be involved in important pathways related to gastrointestinal cancer development. Overall, we provide a rich ... Gastrointestinal Neoplasms / genetics* * Gene Expression Profiling * Gene Expression Regulation, Neoplastic* * Humans * RNA, ... Systematic study of novel lncRNAs in different gastrointestinal cancer cells Discov Med. 2016 Mar;21(115):159-71. ... Material and methods: To investigate the association of lncRNAs to gastrointestinal cancers, 12 cases of esophageal cancer and ...
ROMAN: A Study to Investigate the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer -...
A Study of Famitinib in Patients With Gastrointestinal Stromal Tumor - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Connective Tissue. Neoplasms, Connective and Soft Tissue. Neoplasms by Histologic Type. Gastrointestinal ... A Study of Famitinib in Patients With Gastrointestinal Stromal Tumor. The safety and scientific validity of this study is the ... MedlinePlus Genetics related topics: Gastrointestinal stromal tumor Genetic and Rare Diseases Information Center resources: ... A Single Arm, Open Label, Multicenter, Phase II Study of Famitinib in Patients With Gastrointestinal Stromal Tumor. ...
Puumala Virus Infections Associated with Cardiovascular Causes of Death - Volume 19, Number 1-January 2013 - Emerging...
... neoplasms, 34.3 ± 20.1 d (n = 3); gastrointestinal, 44 ± 39.5 d (n = 2); infections, 77.5 ± 16.3 d (n = 2); endocrine, 22 d (n ... neoplasms (C00-D48); gastrointestinal diseases (K55-K63); infectious diseases (A00-B99, excluding A94.0 and A98.5); endocrine ... Causes of death for remaining persons in the cohort were neoplasms, infectious diseases, endocrine diseases, and CNS diseases ( ...
Neoplasm - Wikipedia
... or gastrointestinal duplications) due to outflow obstructions or narrowings, or abnormal connections, may also present as a ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... p. Neoplasm. ISBN 978-0781733908. .. *^ "II Neoplasms". International Statistical Classification of Diseases and Related Health ... The term neoplasm is a synonym of tumor. Neoplasia denotes the process of the formation of neoplasms/tumors, and the process is ...
Colorectal Cancer | Baylor Medicine
Dr. Dilendra Weerasinghe, MD | Bariatric Surgery in Trinity, FL | Healthline FindCare
NIOSHTIC-2 Search Results - Full View
Dr. Faiz Shakir, MD - Gastroenterology Specialist in Sandy, UT | Healthgrades
Pathology for the Physical Therapist Assistant - 9780323395496
4. The Gastrointestinal System 5. The Renal and Urologic Systems. 6. Central Nervous System Neoplasms 7. Epilepsy. 8. Headache ... Musculoskeletal Neoplasms. 17. Bone, Joint, and Soft Tissue Diseases and Disorders Section 4: Pathology of the Nervous System. ... Twelve e-chapters offer supplemental information in the areas of behavioral issues, the gastrointestinal system, vestibular ...
Gastric tissue biopsy and culture
Epithelial neoplasms of the stomach. In: Iacobuzio-Donahue CA, Montgomery E, eds. Gastrointestinal and Liver Pathology. 2nd ed ... Sleisenger and Fordtrans Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: ... Sleisenger and Fordtrans Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: ...
Find a Doctor in Your Area: Search Results - Sharecare
Gastric Neoplasms: A Multidisciplinary Approach via the SAGES Surgical Calendar
Breast Cancer Screening: Group Education | The Community Guide
... splenic neoplasms/ or exp *thoracic neoplasms/. *** Bold terms replace "exp *gastrointestinal neoplasms/" ... cecal neoplasms/ or exp *duodenal neoplasms/ or exp *ileal neoplasms/ or exp *jejunal neoplasms/ or exp *stomach neoplasms/ or ... cecal neoplasms/ or exp *duodenal neoplasms/ or exp *ileal neoplasms/ or exp *jejunal neoplasms/ or exp *stomach neoplasms/ or ... pc or exp COLONIC NEOPLASMS/pc or exp SIGMOID NEOPLASMS/pc or exp RECTAL NEOPLASMS/pc or exp ANUS NEOPLASMS/pc or exp NEOPLASMS ...
Familial Adenomatous Polyposis Treatment & Management: Medical Care, Surgical Care, Consultations
Malignant neoplasms of the large intestine. Feldman M, Friedman LS, Brandt LJ, eds. In: Sleisenger & Fordtrans ... ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol. ... Division of Gastrointestinal Endoscopy, Atlanta Veterans Affairs Medical Center. Kamil Obideen, MD is a member of the following ... American Society for Gastrointestinal Endoscopy. Disclosure: Nothing to disclose. ...
Publications | Benny Geiger's
LEVY, R; CZERNOBILSKY, B; GEIGER, B (1988). STUDY OF CYTOKERATINS IN GASTROINTESTINAL-TRACT AND ITS NEOPLASMS. Journal Of ... Levy, R; Czernobilsky, B; Geiger, B (1992). Cytokeratin polypeptide in gastrointestinal adenocarcinomas displaying squamous ... COEXPRESSION OF NEURO-ENDOCRINE MARKERS AND EPITHELIAL CYTOSKELETAL PROTEINS IN BRONCHOPULMONARY NEURO-ENDOCRINE NEOPLASMS. ...
Advanced Search Results - Public Health Image Library(PHIL)
Gengraf Oral Solution (Cyclosporine Oral Solution): Uses, Dosage, Side Effects, Interactions, Warning
Neoplasms: skin malignancies [squamous cell (0.9%) and basal cell (0.4%) carcinomas]. Reticuloendothelial: platelet, bleeding, ... Gastrointestinal: constipation, dysphagia, enanthema, eructation, esophagitis, gastric ulcer, gastritis, gastroenteritis, ... Neoplasms: breast fibroadenosis, carcinoma. Psychiatric: anxiety, confusion, decreased libido, emotional lability, impaired ... The most common forms of neoplasms are non-Hodgkins lymphoma and carcinomas of the skin. The risk of malignancies in ...
TractTumorsPancreatic NeoplasmsCancersStromal tumorMalignantCancerComputed TomographyGastroesophageal RefluxAmerican Society fGISTPancreasBenign NeoplasmMucinous neoplasmLymphomaUpper gastrointNeuroendocrinePrimaryCarcinomaStomachComplicationsDisordersEpithelialClinicalDisorderIncidenceEndoscopicSynonym
Tract12
- The gastrointestinal (GI) tract is one of the most frequent primary sites of NETs, and 12-22% of patients with NETs harbor metastatic lesions at the time of initial clinical diagnosis [ 1 ]. (biomedcentral.com)
- Consequently, this article focuses on the more common benign and malignant neoplasms of the GI tract in children, in addition to information gleaned from the relatively sparse literature. (medscape.com)
- Combined modality therapy of gastrointestinal tract cancer / P. Schlag, P. Hohenberger, U. Metzger (eds. (who.int)
- Gastrointestinal disorder (functional problems of gastrointestinal tract) is found to be associated with 2,263 drugs and 1,807 conditions by eHealthMe. (ehealthme.com)
- Esophageal cancer is one of the leading causes of mortality among the neoplasms that affect the gastrointestinal tract. (scielo.br)
- Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL . (bvsalud.org)
- All but one failure in the EGD group was secondary to a lack of a bulge seen in the gastrointestinal (GI) tract. (micrornaarray.com)
- NETs are a group of tumors with heterogenous malignancy that evolve from neuroendocrine cells, with the lung being the second target organ after the gastrointestinal tract. (spandidos-publications.com)
- In addition to the single pulmonary localizations there have been cases described of two or more carcinoid tumors or tumorlets of the lung, gastrointestinal tract and pancreas. (spandidos-publications.com)
- Ampullary cancer accounts for approximately 0.5% of all gastrointestinal tract malignancies. (medscape.com)
- The multicomponent peptide complex LowacidTIDE PLUS forte is a natural and safe product for normalizing functions of the mucous membranes of the gastrointestinal tract in chronic gastritis with low acidity. (personalizedotc.com)
- Peptides normalize functions of the gastrointestinal tract in chronic gastritis with low acidity and restore, heal cells of gastric tissues. (personalizedotc.com)
Tumors11
- Streptozocin (STZ) is used for treating both pancreatic (PanNET) and gastrointestinal (GI-NET) neuroendocrine tumors but its therapeutic efficacy is relatively low in GI-NETs. (biomedcentral.com)
- What Are Gastrointestinal Stromal Tumors? (medlineplus.gov)
- How Are Gastrointestinal Stromal Tumors Diagnosed? (medlineplus.gov)
- How Are Gastrointestinal Stromal Tumors Staged? (medlineplus.gov)
- What Are the Risk Factors for Gastrointestinal Stromal Tumors? (medlineplus.gov)
- Do We Know What Causes Gastrointestinal Stromal Tumors? (medlineplus.gov)
- For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
- Gastrointestinal stromal tumors (GIST) are a heterogeneous group of neoplasms whose biologic behavior is difficult to predict. (cun.es)
- Recent studies show favorable diagnosis efficiency in a variety of tumors, especially in gastrointestinal cancer, but the previous studies were all small-sample data or case reports. (centerwatch.com)
- Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms most frequently found in the stomach and presenting without symptoms or with unspecific ones such as hemorrhage and abdominal pain. (irb.hr)
- [ 1 ] Prior to the recently reported increase, the quoted incidence for ampullary carcinoma was 0.2% of all gastrointestinal malignancies and 6% of all periampullary tumors. (medscape.com)
Pancreatic Neoplasms3
- A gastrointestinal pathologist, she runs a research laboratory dedicated to the evolutionary biology and genetics of pancreatic neoplasms. (agora-gallery.com)
- EUS has an integral role in the diagnosis of pancreatic cancer given its high sensitivity for detecting pancreatic neoplasms and the access it affords to perform fine needle aspiration (FNA) of the suspected lesions. (abdominalkey.com)
- Carcinoma of the ampulla of Vater tends to manifest early due to biliary outflow obstruction, as opposed to pancreatic neoplasms that often are advanced at the time of diagnosis. (medscape.com)
Cancers4
- To investigate the association of lncRNAs to gastrointestinal cancers, 12 cases of esophageal cancer and hepatic cancer, 16 cases of gastric cancer and colorectal cancer and their matched adjacent tissue samples, 12 esophageal cancer cell lines, 7 gastric cancer cell lines, 10 colorectal cancer cell lines, and 11 hepatic cancer cell lines were examined. (nih.gov)
- [7] Malignant neoplasms are also simply known as cancers and are the focus of oncology . (wikipedia.org)
- Smad4, a tumor suppressor, is often mutated in human gastrointestinal cancers. (elsevier.com)
- The alteration of ELF and/or Smad4 expression and function in the TGF-beta signaling pathway may be induced by enhancement of ELF degradation, which is mediated by the high level expression of PRAJA in gastrointestinal cancers. (elsevier.com)
Stromal tumor3
- What Happens After Treatment for Gastrointestinal Stromal Tumor? (medlineplus.gov)
- The purpose of this study is to evaluate the efficacy and safety profile of Famitinib in patients with advanced or metastatic gastrointestinal stromal tumor who failed from imatinib therapy. (clinicaltrials.gov)
- Unresectable advanced or metastatic, histologically-confirmed, gastrointestinal stromal tumor.Patients has been failed from last imatinib treatment due to disease progression or unacceptable toxicity and unable to use sunitinib. (clinicaltrials.gov)
Malignant14
- benign neoplasms , in situ neoplasms , malignant neoplasms , and neoplasms of uncertain or unknown behavior. (wikipedia.org)
- A neoplasm can be benign , potentially malignant, or malignant ( cancer ). (wikipedia.org)
- Potentially-malignant neoplasms include carcinoma in situ . (wikipedia.org)
- Malignant neoplasms are commonly called cancer. (wikipedia.org)
- C48.1 Malignant neoplasm of specified parts of peri. (icd10data.com)
- C48.2 Malignant neoplasm of peritoneum, unspecified. (icd10data.com)
- C48.8 Malignant neoplasm of overlapping sites of re. (icd10data.com)
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
- FAP can be detected in various of malignant neoplasms and is associated to tumor cell migration, invasion, and angiogenesis. (centerwatch.com)
- Epithelioid angiosarcoma is a rare malignant neoplasm found in vascular endothelial cells. (bvsalud.org)
- Angiosarcoma is a rare malignant vascular neoplasm which constitutes less than 1% of all sarcomas. (bvsalud.org)
- Epithelioid angiosarcoma (EA) is a rare variant of angiosarcoma, which is characterized by a high-grade malignant neoplasm, which consists of an atypical, multilayered, or solid endothelial proliferation and vasoformative architecture, presenting necrosis and an area of hemorrhage 1-5 . (bvsalud.org)
- BACKGROUND: Worldwide, colorectal cancer (CRC) is a malignant neoplasm that affects both genders. (unifesp.br)
Cancer13
- Gastrointestinal cancer / edited by Jerome J. DeCosse and Paul Sherlock. (who.int)
- This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the pathophysiology and treatment of gastrointestinal complications, including constipation, impaction, bowel obstruction, diarrhea, and radiation enteritis. (nih.gov)
- Gastrointestinal complications such as constipation, impaction, bowel obstruction, diarrhea, and radiation enteritis are common problems for patients with cancer. (nih.gov)
- In addition, we analyzed the differentially expressed lncRNAs in gastrointestinal cancer cells before and after treatment with 5-Aza. (nih.gov)
- Based on RNA-Seq and bioinformatics analysis, we have identified a significant number of novel lncRNAs, which could be involved in important pathways related to gastrointestinal cancer development. (nih.gov)
- Overall, we provide a rich resource for identifying new biomarkers and studying novel lncRNA regulation pathways in gastrointestinal cancer. (nih.gov)
- Secondary neoplasm refers to any of a class of cancerous tumor that is either a metastatic offshoot of a primary tumor, or an apparently unrelated tumor that increases in frequency following certain cancer treatments such as chemotherapy or radiotherapy . (wikipedia.org)
- Rarely there can be a metastatic neoplasm with no known site of the primary cancer and this is classed as a cancer of unknown primary origin . (wikipedia.org)
- Inactivation of the TGF-beta pathway often occurs in malignancies of the gastrointestinal system, including gastric cancer. (elsevier.com)
- Conversely, biannual endoscopy is recommended in the Manual of Gastric Cancer Screening published by the Japanese Society of Gastrointestinal Cancer Screening ( 7,8 ). (lww.com)
- Not taking the opportunity to obtain gastric biopsy samples for Helicobacter pylori testing during upper gastrointestinal endoscopy is a mistake in patients with dyspepsia or in the setting of a family history of gastric cancer. (ueg.eu)
- Glutathione S-transferases genes variants and chemotherapy efficacy in gastrointestinal cancer patients: a meta-analysis based on 50 pharmacogenetic studies. (cdc.gov)
- The 5-year survival rate for pancreatic cancer is 5%, which is the lowest among gastrointestinal malignancies. (abdominalkey.com)
Computed Tomography1
- We report the case of a male patient with obscure overt gastrointestinal bleed in whom repeated upper gastrointestinal endoscopy, colonoscopy, computed tomography scanning and exploratory laparotomy showed no specific pathology. (who.int)
Gastroesophageal Reflux1
- Gastrointestinal problems including gastroesophageal reflux disease, constipation, and. (bvsalud.org)
American Society f1
- During the investigation of chronic diarrhoea, for instance, sampling normal-appearing colonic mucosa is the only method available for diagnosing microscopic colitis and is one of the quality indicators in colonoscopy according to the American Society for Gastrointestinal Endoscopy (ASGE). (ueg.eu)
GIST1
- This educational symposium will update the medical community on the state-of-the-art care of gastric neoplasms while focusing on the importance of a multidisciplinary approach to the diagnosis and treatment of these rare and complicated disease entities including GIST and gastric adenocarcinoma. (sages.org)
Pancreas2
- Intraductal papillary mucinous neoplasm of pancreas, high grade. (webpathology.com)
- Duodenal diverticula mimicking cystic neoplasm of the pancreas: CT and MR imaging findings in seven patients. (clinicalimaging.org)
Benign Neoplasm1
- A musculoskeletal system benign neoplasm that is located_in connective tissue. (mcw.edu)
Mucinous neoplasm3
- Management of low-grade appendiceal mucinous neoplasm (LAMN) is controversial, and we discuss the importance of the case. (hindawi.com)
- The case of young male post stump appendectomy with histopathology showing LAMN in the stump of the appendix, which to our knowledge, is the first in the medical literature and, discuss the stump appendicitis and incomplete appendectomy concerning malignancy, mucinous neoplasm, and adenocarcinoma. (hindawi.com)
- At the same time, the histopathology of the stump showed appendix measuring 4 cm in length and 0.6 cm in diameter with low-grade appendiceal mucinous neoplasm (LAMN) (Figures 5 - 7 ). (hindawi.com)
Lymphoma2
- For lymphoid neoplasms, e.g. lymphoma and leukemia , clonality is proven by the amplification of a single rearrangement of their immunoglobulin gene (for B cell lesions) or T cell receptor gene (for T cell lesions). (wikipedia.org)
- Increased susceptibility to infection and the possible development of lymphoma and other neoplasms may result from the increase in the degree of immunosuppression in transplant patients. (rxlist.com)
Upper gastroint3
- Upper gastrointestinal endoscopy detected esophageal and duodenal varices. (go.jp)
- Upper gastrointestinal endoscopy detected a submucosal lesion and computerized tomography revealed a node near the liver. (irb.hr)
- 6 When there is a clinical and/or serological suspicion of coeliac disease, biopsy samples should be obtained during upper gastrointestinal endoscopy, both from the bulb and distal duodenum, while the patient is on a gluten-containing diet. (ueg.eu)
Neuroendocrine5
- In this study, we examined the MGMT and GLUT2 status in gastrointestinal neuroendocrine neoplasm (NEN). (biomedcentral.com)
- We studied 84 NEN cases: 33 foregut and 37 hindgut GI-NETs and 14 gastrointestinal neuroendocrine carcinomas (GI-NECs). (biomedcentral.com)
- Abdel-Rahman O , Ghosh S , Morrish D . Impact of baseline body mass index on the outcomes of patients with neuroendocrine neoplasms. (wjgnet.com)
- Lan X , Fazio N, Abdel-rahman O. Exploring the Relationship between Obesity, Metabolic Syndrome and Neuroendocrine Neoplasms. (wjgnet.com)
- Budek M , Nuszkiewicz J , Piórkowska A , Czuczejko J , Szewczyk-Golec K . Inflammation Related to Obesity in the Etiopathogenesis of Gastroenteropancreatic Neuroendocrine Neoplasms. (wjgnet.com)
Primary9
- Primary gastrointestinal (GI) neoplasms in children are rare. (medscape.com)
- Multiple primary neoplasms (MPNs) are of rare occurrence. (biomedres.us)
- The majority of MPNs are double primary neoplasms while triple and quadruple primary neoplasms are extremely rare. (biomedres.us)
- Here, we report a rare case of a 78-year-old woman diagnosed with simultaneous triple primary neoplasms in the ascending colon, the transverse colon and the appendix. (biomedres.us)
- Simultaneous triple primary neoplasms are uncommon cases. (biomedres.us)
- Surgery-based comprehensive therapy is the recommended therapy for simultaneous multiple primary neoplasms. (biomedres.us)
- Multiple primary neoplasms (MPNs) were not recognized until the 1890s [1]. (biomedres.us)
- The majority of MPNs are metachronous double primary neoplasms, while simultaneous triple and quadruple primary neoplasms are much rarer [6]. (biomedres.us)
- clonality studies suggest that most of these neoplasms are separate primary lesions. (cancer.gov)
Carcinoma1
- [12] [13] Some neoplasms do not form a tumor - these include leukemia and most forms of carcinoma in situ . (wikipedia.org)
Stomach1
- Epithelial neoplasms of the stomach. (ucsfhealth.org)
Complications1
- Bhattacharya S, Pavletic S, Heller T. Gastrointestinal complications of hematopoietic cell transplant in: Savani BN, ed. (nih.gov)
Disorders1
- Various neuromuscular, reproductive, gastrointestinal, and urologic disorders may cause or contribute to chronic pain. (medicineshoppe.com)
Epithelial1
- CAFs are the predominant component in the stroma of epithelial neoplasms. (centerwatch.com)
Clinical1
- The phase IV clinical study analyzes which people take Effexor xr and have Gastrointestinal disorder. (ehealthme.com)
Disorder4
- Gastrointestinal disorder is found among people who take Effexor xr, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. (ehealthme.com)
- Among them, 140 people (0.46%) have Gastrointestinal disorder. (ehealthme.com)
- What is Gastrointestinal disorder? (ehealthme.com)
- Do you take Effexor xr and have Gastrointestinal disorder? (ehealthme.com)
Incidence1
- Interestingly, the incidence of pancreatic endocrine neoplasms increased over the same time periods by 106% in men and 125% in women. (abdominalkey.com)
Endoscopic1
- 1 , 2 Current guidelines do not recommend antithrombotic discontinuation for low-risk endoscopic procedures, 3 , 4 with European Society of Gastrointestinal Endoscopy (ESGE) guidelines suggesting an international normalized ratio (INR) check and warfarin dose adjustment one week prior to the procedure. (ueg.eu)
Synonym1
- In modern English, tumor is used as a synonym for neoplasm (a solid or fluid-filled cystic lesion that may or may not be formed by an abnormal growth of neoplastic cells) that appears enlarged in size. (wikipedia.org)