AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsTechnology, Industry, AgricultureHumanitiesInformation ScienceHealth CareGeographicals
Carcinoid TumorGastrointestinal NeoplasmsAppendiceal NeoplasmsMalignant Carcinoid SyndromeCarcinoid Heart DiseaseIleal NeoplasmsBronchial NeoplasmsHydroxyindoleacetic AcidIntestinal NeoplasmsChromograninsOctreotideNeuroendocrine TumorsChromogranin AACTH Syndrome, EctopicAppendixAsparaginasePrecursor Cell Lymphoblastic Leukemia-LymphomaBostonSick Building SyndromeEncyclopedias as TopicParaneoplastic Endocrine SyndromesPaneth CellsAppendicitisDigestive SystemTomography, X-Ray ComputedArchivesBiological Science DisciplinesPeriodicals as TopicPubMedDirectories as TopicPublishingGastroenterologyGermanyCatsHepatic ArteryNeurosecretory SystemsEmbolization, TherapeuticSkin NeoplasmsDermatologyNeoplasm MetastasisMedical Laboratory ScienceTechnology, High-CostEndocrine Gland NeoplasmsHistory, 18th CenturyHistory, 19th CenturyHistory, 20th CenturyEndocrine GlandsNaval MedicineEndocrine SystemIleitisCrohn DiseaseC-Reactive ProteinNew Jersey
Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)Gastrointestinal Neoplasms: Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.Appendiceal Neoplasms: Tumors or cancer of the APPENDIX.Malignant Carcinoid Syndrome: A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)Carcinoid Heart Disease: Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.Ileal Neoplasms: Tumors or cancer in the ILEUM region of the small intestine (INTESTINE, SMALL).Bronchial Neoplasms: Tumors or cancer of the BRONCHI.Hydroxyindoleacetic AcidIntestinal Neoplasms: Tumors or cancer of the INTESTINES.Chromogranins: A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.Octreotide: A potent, long-acting synthetic SOMATOSTATIN octapeptide analog that inhibits secretion of GROWTH HORMONE and is used to treat hormone-secreting tumors; DIABETES MELLITUS; HYPOTENSION, ORTHOSTATIC; HYPERINSULINISM; hypergastrinemia; and small bowel fistula.Neuroendocrine Tumors: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.Chromogranin A: A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.ACTH Syndrome, Ectopic: Symptom complex due to ACTH production by non-pituitary neoplasms.Appendix: A worm-like blind tube extension from the CECUM.Asparaginase: A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.BostonSick Building Syndrome: A group of symptoms that are two- to three-fold more common in those who work in large, energy-efficient buildings, associated with an increased frequency of headaches, lethargy, and dry skin. Clinical manifestations include hypersensitivity pneumonitis (ALVEOLITIS, EXTRINSIC ALLERGIC); allergic rhinitis (RHINITIS, ALLERGIC, PERENNIAL); ASTHMA; infections, skin eruptions, and mucous membrane irritation syndromes. Current usage tends to be less restrictive with regard to the type of building and delineation of complaints. (From Segen, Dictionary of Modern Medicine, 1992)Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Paraneoplastic Endocrine Syndromes: Syndromes resulting from inappropriate production of HORMONES or hormone-like materials by NEOPLASMS in non-endocrine tissues or not by the usual ENDOCRINE GLANDS. Such hormone outputs are called ectopic hormone (HORMONES, ECTOPIC) secretion.Paneth Cells: Differentiated epithelial cells of the INTESTINAL MUCOSA, found in the basal part of the intestinal crypts of Lieberkuhn. Paneth cells secrete GROWTH FACTORS, digestive enzymes such as LYSOZYME and antimicrobial peptides such as cryptdins (ALPHA-DEFENSINS) into the crypt lumen.Appendicitis: Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated.Digestive System: A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Gastroenterology: A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).GermanyCats: The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)Hepatic Artery: A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.Neurosecretory Systems: A system of NEURONS that has the specialized function to produce and secrete HORMONES, and that constitutes, in whole or in part, an ENDOCRINE SYSTEM or organ.Embolization, Therapeutic: A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.Skin Neoplasms: Tumors or cancer of the SKIN.Dermatology: A medical specialty concerned with the skin, its structure, functions, diseases, and treatment.Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Medical Laboratory Science: The specialty related to the performance of techniques in clinical pathology such as those in hematology, microbiology, and other general clinical laboratory applications.Technology, High-Cost: Advanced technology that is costly, requires highly skilled personnel, and is unique in its particular application. Includes innovative, specialized medical/surgical procedures as well as advanced diagnostic and therapeutic equipment.Endocrine Gland Neoplasms: Tumors or cancer of the ENDOCRINE GLANDS.History, 18th Century: Time period from 1701 through 1800 of the common era.History, 19th Century: Time period from 1801 through 1900 of the common era.History, 20th Century: Time period from 1901 through 2000 of the common era.Endocrine Glands: Ductless glands that secrete HORMONES directly into the BLOOD CIRCULATION. These hormones influence the METABOLISM and other functions of cells in the body.Naval Medicine: The practice of medicine concerned with conditions affecting the health of individuals associated with the marine environment.Endocrine System: The system of glands that release their secretions (hormones) directly into the circulatory system. In addition to the ENDOCRINE GLANDS, included are the CHROMAFFIN SYSTEM and the NEUROSECRETORY SYSTEMS.Ileitis: Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.C-Reactive Protein: A plasma protein that circulates in increased amounts during inflammation and after tissue damage.New Jersey
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsTechnology, Industry, AgricultureHumanitiesInformation ScienceHealth CareGeographicals
Carcinoid TumorGastrointestinal NeoplasmsAppendiceal NeoplasmsMalignant Carcinoid SyndromeCarcinoid Heart DiseaseIleal NeoplasmsBronchial NeoplasmsHydroxyindoleacetic AcidIntestinal NeoplasmsChromograninsOctreotideNeuroendocrine TumorsChromogranin AACTH Syndrome, EctopicAppendixAsparaginasePrecursor Cell Lymphoblastic Leukemia-LymphomaBostonSick Building SyndromeEncyclopedias as TopicParaneoplastic Endocrine SyndromesPaneth CellsAppendicitisDigestive SystemTomography, X-Ray ComputedArchivesBiological Science DisciplinesPeriodicals as TopicPubMedDirectories as TopicPublishingGastroenterologyGermanyCatsHepatic ArteryNeurosecretory SystemsEmbolization, TherapeuticSkin NeoplasmsDermatologyNeoplasm MetastasisMedical Laboratory ScienceTechnology, High-CostEndocrine Gland NeoplasmsHistory, 18th CenturyHistory, 19th CenturyHistory, 20th CenturyEndocrine GlandsNaval MedicineEndocrine SystemIleitisCrohn DiseaseC-Reactive ProteinNew Jersey
5-Hydroxyindoleacetic acid5-Hydroxyindoleacetic acid
"Carcinoid tumour of the gastrointestinal tract: prognostic factors and disease outcome". J Surg Oncol. 47 (1): 45-52. doi: ... Tumors derived from hindgut cells (rectal carcinoid) rarely produce excess serotonin or 5-HIAA. Of 75 patients with carcinoid ... 5-HIAA may be normal with nonmetastatic carcinoid tumor and may be normal even with the carcinoid syndrome, particularly in ... Serotonin, and consequently 5-HIAA, are produced in excess by most carcinoid tumors, especially those producing the carcinoid ...
Enteroendocrine cellEnteroendocrine cell
Rare and slow growing carcinoid and non-carcinoid tumors develop from these cells. When a tumor arises it has the capacity to ... APUD cells Neuroendocrine tumors Rehfeld, Jens F (1998). "The New Biology of Gastrointestinal Hormones". Physiol. Rev. 78: 1087 ... Warner, RR (May 2005). "Enteroendocrine tumors other than carcinoid: a review of clinically significant advances". ... They produce gastrointestinal hormones or peptides in response to various stimuli and release them into the bloodstream for ...
Appendix (anatomy)Appendix (anatomy)
The most common diseases of the appendix (in humans) are appendicitis and carcinoid tumors (appendiceal carcinoid). Appendix ... cholera or to boost it following a milder gastrointestinal illness. The appendix has been identified as an important component ... preserving the flora during times of gastrointestinal infection in societies without modern medicine. This function is ... cancer accounts for about 1 in 200 of all gastrointestinal malignancies. In rare cases, adenomas are also present. Appendicitis ...
Hormonal therapy (oncology)Hormonal therapy (oncology)
It is also effective in suppression of the carcinoid syndrome, caused by advanced or extra-gastrointestinal carcinoid tumors. ... The exact mechanism of action of these hormones is unclear, and may involve both direct effect on the tumor cells (suppression ... One effective strategy for starving tumor cells of growth- and survival-promoting hormones is to use drugs which inhibit the ... Octreotide is used for suppression of the hormonal syndromes which accompany several pancreatic islet cell tumors, including ...
String signString sign
It may be seen in Crohn's disease, hypertrophic pyloric stenosis, carcinoid tumor and colon cancer. In people with Crohn's ... The gastrointestinal string sign represents a severe narrowing of loop of bowel, in which a thin stripe of contrast within the ... String sign, or gastrointestinal string sign (also called string sign of Kantour) , is a medical term for a radiographic ...
Appendix (anatomy)Appendix (anatomy)
The most common diseases of the appendix (in humans) are appendicitis and carcinoid tumors (appendiceal carcinoid).[21] ... Appendix cancer accounts for about 1 in 200 of all gastrointestinal malignancies. In rare cases, adenomas are also present.[22] ... preserving the flora during times of gastrointestinal infection in societies without modern medicine. This function is ... gut flora in the digestive system following a bout of dysentery or cholera or to boost it following a milder gastrointestinal ...
Cardiac fibrosisCardiac fibrosis
Certain diseases such as gastrointestinal carcinoid tumors of the mid-gut, which sometimes release large amounts of 5- ...
Liver cancerLiver cancer
... colon cancer and carcinoid tumors mainly of the appendix), but also from breast cancer, ovarian cancer, lung cancer, renal ... the site of origin is the gastrointestinal tract, since the liver is close to many of these metabolically active, blood-rich ... whether due to spread of the initial tumor or formation of new tumors . Liver transplantation can also be considered in cases ... Tumor markers, chemicals sometimes found in the blood of people with cancer, can be helpful in diagnosing and monitoring the ...
Small intestineSmall intestine
Adenocarcinoma Carcinoid Gastrointestinal stromal tumor (GIST) Lymphoma Sarcoma Leiomyoma Metastatic tumors, especially SCLC or ... The small intestine or small bowel is the part of the gastrointestinal tract between the stomach and the large intestine, and ... "The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling ... ulcers Gastrointestinal perforation Hyperthyroidism Diverticulitis Radiation enterocolitis Mesenteric cysts Peritoneal ...
Small intestine cancerSmall intestine cancer
These include: adenocarcinoma gastrointestinal stromal tumor lymphoma ileal carcinoid tumor Risk factors for small intestine ... It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer (stomach cancer) and colorectal ... Micrograph of a small intestine neuroendocrine tumour. H&E stain. "SEER Stat Fact Sheets: Small Intestine Cancer". NCI. ... mice which carry a gene deficiency corresponding to that of humans with FAP also go on to develop small intestinal tumors, ...
CarcinoidCarcinoid
Over two-thirds of carcinoid tumors are found in the gastrointestinal tract. Carcinoid tumors are also found in the lungs. ... Carcinoid tumors of the midgut (jejunum, ileum, appendix, and cecum) are associated with carcinoid syndrome. Carcinoid tumors ... "ACS :: What Is a Gastrointestinal Carcinoid Tumor?". Cunningham JL, Janson ET (2011). "The Hallmarks of Ileal Carcinoids". Eur ... Carcinoid (also carcinoid tumor) is a slow-growing type of neuroendocrine tumor originating in the cells of the neuroendocrine ...
Gastrointestinal cancerGastrointestinal cancer
The five-year survival rate with the latter procedure is above 70%. A gastrointestinal carcinoid tumor is a rare, slow-growing ... first1= missing ,last1= in Authors list (help)CS1 maint: Extra text: authors list (link) "Gastrointestinal Carcinoid Tumor". ... Gastrointestinal stromal tumors represent from 1% to 3% of gastrointestinal malignancies. Cancers of the biliary tree, ... Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract (GI tract) and accessory organs of ...
Neuroendocrine tumorNeuroendocrine tumor
Gastrointestinal Carcinoid Tumors Treatment cancer.gov National Cancer Institute. Merkel cell tumors, cancer.gov National ... Carcinoid Tumor Overview. healthcommunities.com Kvols LK. 2002. Carcinoid Tumors and the Carcinoid Syndrome: What's New in the ... gastrointestinal carcinoids, Merkel cell tumors and pheochromocytoma/paraganglioma. Even if the tumor has advanced and ... Parathyroid tumors Thymus and mediastinal carcinoid tumors Pulmonary neuroendocrine tumorsbronchus pulmonary carcinoid tumors: ...
Meckels diverticulumMeckel's diverticulum
Carcinoids: most common, 44% Mesenchymal tumors: Leiomyosarcoma, peripheral nerve sheath and gastrointestinal stromal tumors, ... Benign tumors: Leiomyoma Lipoma Vascular and neuromuscular hamartoma Malignant tumors: ... Tumors e.g. carcinoma: direct spread of an adenocarcinoma arising in the diverticulum may lead to obstruction Lithiasis, stones ... Gastrointestinal bleeding may be self-limiting but chronic bleeding may lead to iron deficiency anaemia. The appearance of ...
Carcinoid syndromeCarcinoid syndrome
When the primary tumor is in the gastrointestinal tract, as it is in the great majority of cases, the serotonin and kallikrein ... Carcinoid syndrome is a paraneoplastic syndrome comprising the signs and symptoms that occur secondary to carcinoid tumors. The ... Play media The carcinoid syndrome occurs in approximately 5% of carcinoid tumors and becomes manifest when vasoactive ... Carcinoid tumors arising in the bronchi may be associated with manifestations of carcinoid syndrome without liver metastases ...
Goblet cell carcinoidGoblet cell carcinoid
... is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, ... The goblet cell carcinoid, abbreviated GCC and also known as crypt cell carcinoma and neuroendocrine tumour with goblet cell ... December 2007). "Goblet cell carcinoid of the appendix: a specific type of carcinoma". Histopathology. 51 (6): 763-73. doi: ...
List of cancer typesList of cancer types
... cancer Gastrointestinal carcinoid tumor Gastrointestinal stromal tumor (GIST) Hepatocellular cancer Pancreatic cancer, islet ... Not all tumors or lumps are cancerous; benign tumors are not classified as being cancer because they do not spread to other ... surface epithelial-stromal tumor) Ovarian germ cell tumor Penile cancer Renal cell carcinoma Renal pelvis and ureter, ... Germ cell tumor: Cancers derived from pluripotent cells, most often presenting in the testicle or the ovary (seminoma and ...
Endocrine oncologyEndocrine oncology
There are many different kinds of endocrine tumors, some of which are listed below: Gastrointestinal ECLoma Midgut carcinoid ... Appendix carcinoid Hindgut carcinoid sometimes also referred to as Rectal carcinoid Pulmonary Typical bronchial carcinoid ... Atypical bronchial carcinoid Large cell neuroendocrine carcinoma Small cell lung cancer Endocrine pancreatic tumors Non- ... Endocrine oncology refers to a medical speciality dealing with hormone producing tumors, i.e. a combination of endocrinology ...
CarcinoidCarcinoid
Gastrointestinal[edit]. Carcinoid tumors are apudomas that arise from the enterochromaffin cells throughout the gut. Over two- ... thirds of carcinoid tumors are found in the gastrointestinal tract.[3]. Lung[edit]. Main article: Typical lung carcinoid tumor ... Carcinoid tumors are also found in the lungs.. Other sites / metastases[edit]. Metastasis of carcinoid can lead to carcinoid ... Carcinoid (also carcinoid tumor) is a slow-growing[1] type of neuroendocrine tumor originating in the cells of the ...
Enterochromaffin cellEnterochromaffin cell
Excess circulating serotonin is usually manufactured by EC-cell-originated carcinoid tumors in the small bowel or appendix. ... They reside alongside the epithelium lining the lumen of the digestive tract and play a crucial role in gastrointestinal ... Carcinoid syndrome[edit]. Carcinoid syndrome is a rare condition characterized by an abnormal increase in circulating ... Tumors are slow growing, but can metastasise to the liver if aggressive. They can also be present at other sites, particularly ...
Appendix cancerAppendix cancer
Gastrointestinal stromal tumors are rare tumors with malignant potential. Primary lymphomas can occur in the appendix. Breast ... cancer, colon cancer, and tumors of the female genital tract may metastasize to the appendix. Small carcinoids (. ...
Desmoplastic small-round-cell tumorDesmoplastic small-round-cell tumor
First symptoms of the disease often include abdominal distention, abdominal mass, abdominal or back pain, gastrointestinal ... and mesenteric carcinoid. In older patients DSRCT can resemble lymphoma, peritoneal mesothelioma, and peritoneal carcinomatosis ... In dogs, mast cell tumors are the most frequent round cell tumor. There are few early warning signs that a patient has a DSRCT ... 2012) E-cadherin in canine mast cell tumors: Decreased expression and altered subcellular localization in Grade 3 tumors. Vet J ...
LanreotideLanreotide
... and the management of symptoms caused by neuroendocrine tumors, particularly carcinoid tumors and VIPomas. In the United States ... The main side effects of lanreotide treatment are mild to moderate pain at the injection site and gastrointestinal disturbances ... In the United Kingdom, it is also indicated in the treatment of thyrotrophic adenoma, a rare tumor of the pituitary gland which ... Lanreotide (INN) is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most ...
Armed Forces Institute of PathologyArmed Forces Institute of Pathology
Miettinen M, Sobin, LH, Lasota J. Gastrointestinal stromal tumors of the stomach. A clinicopathologic, immunohistochemical, and ... Duodenal carcinoids: Imaging Features with Clinicopathologic Comparison. Radiology 2005;237:967-972 "Building a Bombproof ... and molecular characteristics of the relatively newly recognized gastrointestinal stromal tumors. Another special feature of ... The AFIP played a critical role in the standardization of pathologic diagnosis of tumors. This was mainly the result of the ...
CecumCecum
A cecal carcinoid tumor is a carcinoid tumor of the cecum. An appendiceal carcinoid tumor (a carcinoid tumor of the appendix) ... Human gastrointestinal tract seen from front (cecum colored red). Superior ileocecal fossa. (cecum labeled at bottom left) ... is sometimes found next to a cecal carcinoid.[citation needed]. Neutropenic enterocolitis (typhlitis) is the condition of ...
AcneAcne
These gene candidates include certain variations in tumor necrosis factor-alpha (TNF-alpha), IL-1 alpha, and CYP1A1 genes, ... appears to have similar efficacy to 100 milligrams daily and has fewer gastrointestinal side effects.[15] However, low-dose ... and androgen-secreting tumors, can cause acne in affected individuals.[45][46] Conversely, people who lack androgenic hormones ... as it may increase certain tumors, which has been shown in animal studies, and the caution that "Unnecessary use of this drug ...
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsTechnology, Industry, AgricultureHumanitiesInformation ScienceHealth CareGeographicals
Carcinoid TumorGastrointestinal NeoplasmsAppendiceal NeoplasmsMalignant Carcinoid SyndromeCarcinoid Heart DiseaseIleal NeoplasmsBronchial NeoplasmsHydroxyindoleacetic AcidIntestinal NeoplasmsChromograninsOctreotideNeuroendocrine TumorsChromogranin AACTH Syndrome, EctopicAppendixAsparaginasePrecursor Cell Lymphoblastic Leukemia-LymphomaBostonSick Building SyndromeEncyclopedias as TopicParaneoplastic Endocrine SyndromesPaneth CellsAppendicitisDigestive SystemTomography, X-Ray ComputedArchivesBiological Science DisciplinesPeriodicals as TopicPubMedDirectories as TopicPublishingGastroenterologyGermanyCatsHepatic ArteryNeurosecretory SystemsEmbolization, TherapeuticSkin NeoplasmsDermatologyNeoplasm MetastasisMedical Laboratory ScienceTechnology, High-CostEndocrine Gland NeoplasmsHistory, 18th CenturyHistory, 19th CenturyHistory, 20th CenturyEndocrine GlandsNaval MedicineEndocrine SystemIleitisCrohn DiseaseC-Reactive ProteinNew Jersey
Carcinoid Heart Disease | JACC: Journal of the American College of CardiologyCarcinoid Heart Disease | JACC: Journal of the American College of Cardiology
The most common primary site of carcinoid tumors is the gastrointestinal tract (60%); one-third of them (34%) arise in the ... Carcinoid tumors are rare (2.5 to 5.0 cases per 100,000 of the population per year), slow-growing neuroendocrine malignancies ... Department of Gastroenterology, Center for Carcinoid and Neuroendocrine Tumors, The Mount Sinai Hospital, New York, New York. ... Department of Cardiovascular Surgery, Center for Carcinoid and Neuroendocrine Tumors, The Mount Sinai Hospital, New York, New ...
onlinejacc.org
Phase 2 Trial of Lexicons LX1032, Telotristat Etiprate, Shows Positive Results in Carcinoid Syndrome - RedorbitPhase 2 Trial of Lexicon's LX1032, Telotristat Etiprate, Shows Positive Results in Carcinoid Syndrome - Redorbit
Carcinoid syndrome is a chronic condition caused by neuroendocrine tumors that usually originate from the gastrointestinal ... About Carcinoid Syndrome. Carcinoid syndrome is a chronic condition caused by metastatic neuroendocrine tumors that usually ... Symptoms of carcinoid syndrome have been linked to excess production of serotonin by metastatic tumor cells. Telotristat ... originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of ...
redorbit.com
High tumour burden, delayed diagnosis and history of cardiovascular disease may be associated with carcinoid heart disease -...High tumour burden, delayed diagnosis and history of cardiovascular disease may be associated with carcinoid heart disease -...
... delayed diagnosis and history of cardiovascular disease may be associated with carcinoid heart disease Carolina Alves1, Marcell ... Guidelines for the management of neuroendocrine tumours by the Brazilian gastrointestinal tumour group Ecancermedicalscience 11 ... 1. Halperin DM, Shen C, and Dasari A, et al (2017) Frequency of carcinoid syndrome at neuroendocrine tumour diagnosis: a ... High tumour burden, delayed diagnosis and history of cardiovascular disease may be associated with carcinoid heart disease. ...
ecancer.org
Carcinoid syndrome | Tumors | ePharmaPediaCarcinoid syndrome | Tumors | ePharmaPedia
If people with carcinoid tumors have a gastrointestinal carcinoid tumor, and particularly if the tumor has spread (metastasized ... The cause of carcinoid tumors is not recognized. A carcinoid tumor that secretes serotonin or other chemicals into the ... The chemicals that cause carcinoid syndrome are secreted only by a small percent of carcinoid tumors, however, these tumors ... the carcinoid lung tumors that secrete them do so much farther upstream. On the other hand, the chemicals of carcinoid tumors ...
epharmapedia.com
Treating Gastrointestinal Carcinoid TumorsTreating Gastrointestinal Carcinoid Tumors
If you are facing gastrointestinal carcinoid tumors , we can help you learn about the treatment options and possible side ... If youve been diagnosed with a gastrointestinal (GI) carcinoid tumor, your cancer care team will discuss your treatment ... Who treats GI carcinoid tumors?. Based on your treatment options, you might have different types of doctors on your treatment ... Whether the tumor is causing bothersome symptoms (including symptoms of carcinoid syndrome) ...
cancer.org
Signs and Symptoms of Gastrointestinal Carcinoid TumorsSigns and Symptoms of Gastrointestinal Carcinoid Tumors
... carcinoids often do not cause any symptoms and may be found when looking for causes of other problems. Learn more about GI ... Signs and Symptoms of Gastrointestinal Carcinoid Tumors. Most gastrointestinal (GI) carcinoids grow slowly. If they do cause ... Signs and symptoms from hormones made by carcinoid tumors. Some carcinoid tumors can release hormones into the bloodstream. ... Carcinoid) Tumors and the Carcinoid Syndrome. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of ...
cancer.org
Gastrointestinal Carcinoid Tumor Surgery | MoffittGastrointestinal Carcinoid Tumor Surgery | Moffitt
Surgery may be recommended to remove a gastrointestinal carcinoid tumor, as well as any nearby lymph nodes or tissues that also ... The most common types of gastrointestinal carcinoid tumor surgery include:. *A local excision, which involves the removal of ... There are several different surgeries that can be recommended for a patient with a gastrointestinal carcinoid tumor; the most ... Referrals are not required to consult with Moffitts expert oncologists about gastrointestinal carcinoid tumor surgery. To meet ...
moffitt.org
Carcinoid Tumor Guidelines: Guidelines Summary, Gastrointestinal Tumors, Thoracic carcinoidsCarcinoid Tumor Guidelines: Guidelines Summary, Gastrointestinal Tumors, Thoracic carcinoids
In children, most tumors occur in the appendix and are benign and asymptomatic. ... Origin and general involvement and presentation Carcinoid tumors are derived from primitive stem cells in the gut wall but can ... and TTF-1 can help distinguish gastrointestinal carcinoid tumors from pancreatic endocrine and pulmonary carcinoid tumors. Am J ... HER2 expression in gastrointestinal carcinoid tumors: high in intestinal but not in gastric tumors. Surg Today. 2007. 37(3):270 ...
emedicine.medscape.com
Gastrointestinal Carcinoid Tumors | Vanderbilt-Ingram Cancer CenterGastrointestinal Carcinoid Tumors | Vanderbilt-Ingram Cancer Center
Stages of Gastrointestinal Carcinoid Tumors Key Points. *After a gastrointestinal carcinoid tumor has been diagnosed, tests are ... The metastatic tumor is the same type of tumor as the primary tumor. For example, if a gastrointestinal (GI) carcinoid tumor ... Gastrointestinal Carcinoid Tumors Treatment General Information About Gastrointestinal Carcinoid Tumors. Go to Health ... Health history can affect the risk of gastrointestinal carcinoid tumors. *Some gastrointestinal carcinoid tumors have no signs ...
vicc.org
Gastrointestinal Carcinoid Tumors Risk Factors, Symptoms & TreatmentGastrointestinal Carcinoid Tumors Risk Factors, Symptoms & Treatment
Some gastrointestinal carcinoid tumors have no signs or symptoms in the early stages. Carcinoid syndrome may occur if the tumor ... A gastrointestinal carcinoid tumor is cancer that forms in the lining of the gastrointestinal tract. ... The metastatic tumor is the same type of tumor as the primary tumor. For example, if a gastrointestinal (GI) carcinoid tumor ... Who Is at Risk for a Gastrointestinal Carcinoid Tumor?. *What Are the Signs and Symptoms of Gastrointestinal Carcinoid Tumors? ...
emedicinehealth.com
Gastrointestinal Carcinoid Tumor | Colorectal Cancer Care | Mercy HealthGastrointestinal Carcinoid Tumor | Colorectal Cancer Care | Mercy Health
Learn about gastrointestinal carcinoid tumors, including causes, risk factors, symptoms, diagnosis and treatment from the ... What is a gastrointestinal carcinoid tumor?. A gastrointestinal carcinoid tumor is a type of cancer that forms in the lining of ... Symptoms of gastrointestinal (GI) carcinoid tumors. In most cases, people with gastrointestinal carcinoid tumors dont have any ... Risk factors for gastrointestinal (GI) carcinoid tumors. Your risk for a GI carcinoid tumor increases if you have any of the ...
mercy.com
Gastrointestinal Carcinoid Tumors Treatment (PDQ®): Treatment - Health Professional Information [NCI] | UW...Gastrointestinal Carcinoid Tumors Treatment (PDQ®): Treatment - Health Professional Information [NCI] | UW...
Carcinoid tumors represent about 0.5% of all newly diagnosed malignancies.[2,3] Anatomy Carcinoid tumors are rare, slow-growing ... Epidemiology The age-adjusted incidence of carcinoid tumors worldwide is approximately 2 per 100,000 persons.[1,2] The average ... General Information About Gastrointestinal (GI) Carcinoid Tumors. Epidemiology The age-adjusted incidence of carcinoid tumors ... Treatment Option Overview for GI Carcinoid Tumors. Standard treatments for patients with gastrointestinal (GI) carcinoid tumors ...
uwhealth.org
Neuroendocrine Tumor of Gastrointestinal Tract, Lung, and Thymus - Carcinoid TumorsNeuroendocrine Tumor of Gastrointestinal Tract, Lung, and Thymus - Carcinoid Tumors
... slow-growing tumors. Some may be functional neuroendocrine tumors (NETs) of the gastrointestinal system, lungs, or thymus. ... Neuroendocrine Tumors of the Gastrointestinal Tract, Lung, and Thymus - Carcinoid Tumors Carcinoid tumors are rare, slow- ... Neuroendocrine Tumors of the Gastrointestinal Tract, Lung, and Thymus - Carcinoid Tumors. ARUP Consult©. Retrieved June 12, ... All Topics › Neuroendocrine Tumors of the Gastrointestinal Tract, Lung, and Thymus - Carcinoid Tumors ...
arupconsult.com
Gastrointestinal neuroendocrine tumors & carcinoid syndrome | MDedge Internal MedicineGastrointestinal neuroendocrine tumors & carcinoid syndrome | MDedge Internal Medicine
Gastrointestinal neuroendocrine tumors & carcinoid syndrome. Take Quiz. Carcinoid syndrome: Clinical features & diagnosis. Take ... Carcinoid syndrome: Clinical evaluation & surgical management. Take Quiz. ...
mdedge.com
Gastrointestinal Carcinoid Tumors | HOA - Hematology-Oncology Associates of CNYGastrointestinal Carcinoid Tumors | HOA - Hematology-Oncology Associates of CNY
... carcinoid tumor treatment options include surgery, radiation therapy, chemotherapy, and hormone therapy. Treatment for ... carcinoid syndrome includes hormonal treatment, interferon, and other medications to control symptoms. Learn more in this ... Gastrointestinal Carcinoid Tumors. Gastrointestinal Carcinoid Tumors Treatment (PDQ®)-Patient Version. General Information ... Stages of Gastrointestinal Carcinoid Tumors Key Points. *After a gastrointestinal carcinoid tumor has been diagnosed, tests are ...
hoacny.com
Top Gastrointestinal Carcinoid Tumors Cancer Symptoms by Cancer Survivors | Blog for a CureTop Gastrointestinal Carcinoid Tumors Cancer Symptoms by Cancer Survivors | Blog for a Cure
Read reports about cancer symptoms by our users with Gastrointestinal Carcinoid Tumors, which involve terms such as abdominal, ... Gastrointestinal Carcinoid Tumors Cancer Symptoms. What Gastrointestinal Carcinoid Tumors Cancer Survivors said about their ... What are Gastrointestinal Carcinoid Tumors Cancer Symptoms? List from Cancer Survivors. The below is a list that has been ...
blogforacure.com
Carcinoid Tumor (Carcinoid Cancer), Staging & Treatment - Dana-Farber Cancer Institute | Boston, MACarcinoid Tumor (Carcinoid Cancer), Staging & Treatment - Dana-Farber Cancer Institute | Boston, MA
Learn about carcinoids and find information on how we support for people with carcinoids before, during, and after treatment. ... A carcinoid is a type of tumor often found in the appendix and sometimes in the lungs. ... About Gastrointestinal Carcinoid Tumors. * Gastrointestinal (GI) carcinoid tumors are slow-growing cancers that form in cells ... Learn about gastrointestinal carcinoid tumors and find information on how we support and care for people with gastrointestinal ...
dana-farber.org
Carcinoid Tumor News, ResearchCarcinoid Tumor News, Research
Gleevec receives FDA priority review for gastrointestinal stromal tumors after surgery Novartis has announced that Gleevec ( ... the recipients of the 2011 Caring for Carcinoid Foundation-AACR Grants for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor ... or time without tumor growth, in patients with advanced carcinoid tumors compared to taking octreotide LAR alone. ... Afinitor-Sandostatin LAR Depot combination extends median PFS in patients with advanced carcinoid tumors A Novartis ...
news-medical.net
Carcinoid Syndrome (Tumor) Symptoms, Prognosis, Survival RateCarcinoid Syndrome (Tumor) Symptoms, Prognosis, Survival Rate
... they may cause carcinoid syndrome. Signs and symptoms of carcinoid syndrome may include facial flushing, diarrhea, heart ... The majority (65%) of carcinoid tumors are found in the gastrointestinal tract. The origin of gastrointestinal carcinoid tumors ... Appendiceal carcinoid tumors. While tumors of the appendix are rare, carcinoid tumors are the most common tumor of the appendix ... What is the prognosis and natural history of carcinoid tumors?. *What is the treatment for carcinoid tumors and carcinoid ...
medicinenet.com
Natural History of Familial Carcinoid Tumor - Full Text View - ClinicalTrials.govNatural History of Familial Carcinoid Tumor - Full Text View - ClinicalTrials.gov
Gastrointestinal. Serotonin. Carcinoid Tumor. Gastrointestinal Carcinoid Tumor. Familial Cancer Tumor. Additional relevant MeSH ... People who already have a small bowel carcinoid tumor or are at risk of developing a carcinoid tumor have some or all of the ... Carcinoid Tumor. Neuroendocrine Tumors. Neuroectodermal Tumors. Neoplasms, Germ Cell and Embryonal. Neoplasms by Histologic ... MedlinePlus related topics: Carcinoid Tumors Genetic and Rare Diseases Information Center resources: Carcinoid Tumor ...
clinicaltrials.gov
Carcinoid - WikipediaCarcinoid - Wikipedia
Gastrointestinal[edit]. Carcinoid tumors are apudomas that arise from the enterochromaffin cells throughout the gut. Over two- ... thirds of carcinoid tumors are found in the gastrointestinal tract.[3]. Lung[edit]. Main article: Typical lung carcinoid tumor ... Carcinoid tumors are also found in the lungs.. Other sites / metastases[edit]. Metastasis of carcinoid can lead to carcinoid ... Carcinoid (also carcinoid tumor) is a slow-growing[1] type of neuroendocrine tumor originating in the cells of the ...
en.wikipedia.org
Carcinoid Tumors: MedlinePlusCarcinoid Tumors: MedlinePlus
Carcinoid tumors can happen in the lungs or digestive tract. Learn about risk factors, tests, treatment, and more. ... What Are Lung Carcinoid Tumors? (American Cancer Society) * What Is a Gastrointestinal Carcinoid Tumor? (American Cancer ... How Are Gastrointestinal Carcinoid Tumors Diagnosed? (American Cancer Society) * How Are Lung Carcinoid Tumors Diagnosed? ( ... Lung Carcinoid Tumor: Surgery (American Cancer Society) * Treatment of Gastrointestinal Carcinoid Tumors by Stage (American ...
medlineplus.gov
Carcinoid Tumor Workup: Laboratory Studies, Imaging Studies, ProceduresCarcinoid Tumor Workup: Laboratory Studies, Imaging Studies, Procedures
In children, most tumors occur in the appendix and are benign and asymptomatic. ... Origin and general involvement and presentation Carcinoid tumors are derived from primitive stem cells in the gut wall but can ... and TTF-1 can help distinguish gastrointestinal carcinoid tumors from pancreatic endocrine and pulmonary carcinoid tumors. Am J ... Carcinoid Tumor) and Carcinoid Tumor What to Read Next on Medscape. Related Conditions and Diseases. * Neuroendocrine Tumors ...
emedicine.medscape.com
Primary Renal Carcinoid Tumor Presenting as an Unusual Calcific MassPrimary Renal Carcinoid Tumor Presenting as an Unusual Calcific Mass
Carcinoid tumors are commonly found in the gastrointestinal (GI) tract; the most common sites are the appendix and small ... In the kidney, 26.8% of the carcinoid tumors are associated with another renal pathology [3]. Carcinoid tumors have been found ... Carcinoid tumors are low-grade malignant tumors commonly found in the GI and respiratory tract. They are very uncommon in the ... Whenever a carcinoid of the kidney is diagnosed, a thorough evaluation for another focus of carcinoid tumor is mandated. This ...
urotoday.com
Gastrointestinal carcinoid tumor. Definition | WikBioGastrointestinal carcinoid tumor. Definition | WikBio
Definition of Gastrointestinal carcinoid tumor. Meaning of Gastrointestinal carcinoid tumor. ... Gastrointestinal carcinoid tumorCancer indolent (slow growing) that forms in cells that produce hormones in the lining of the ... Gastrointestinal carcinoid tumor. Definition. Medical Definition: Gastrointestinal carcinoid tumor. Cancer indolent (slow ... Suffer from gastrointestinal carcinoid tumor increases the risk of forming other cancers of the digestive system. ...
wikbio.com
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsTechnology, Industry, AgricultureHumanitiesInformation ScienceHealth CareGeographicals
Carcinoid TumorGastrointestinal NeoplasmsAppendiceal NeoplasmsMalignant Carcinoid SyndromeCarcinoid Heart DiseaseIleal NeoplasmsBronchial NeoplasmsHydroxyindoleacetic AcidIntestinal NeoplasmsChromograninsOctreotideNeuroendocrine TumorsChromogranin AACTH Syndrome, EctopicAppendixAsparaginasePrecursor Cell Lymphoblastic Leukemia-LymphomaBostonSick Building SyndromeEncyclopedias as TopicParaneoplastic Endocrine SyndromesPaneth CellsAppendicitisDigestive SystemTomography, X-Ray ComputedArchivesBiological Science DisciplinesPeriodicals as TopicPubMedDirectories as TopicPublishingGastroenterologyGermanyCatsHepatic ArteryNeurosecretory SystemsEmbolization, TherapeuticSkin NeoplasmsDermatologyNeoplasm MetastasisMedical Laboratory ScienceTechnology, High-CostEndocrine Gland NeoplasmsHistory, 18th CenturyHistory, 19th CenturyHistory, 20th CenturyEndocrine GlandsNaval MedicineEndocrine SystemIleitisCrohn DiseaseC-Reactive ProteinNew Jersey
TractSyndromeMetastasesLiverSymptomsDiseaseSerotoninIntestinalMetastatic diseaseMidgutNETSHormonesClinicalOctreotideGastricLymphomaOriginatePrimary tumorGISTCarcinomaPulmonary carcinoid tumorsNeuroendocrine cellsAppendicealAriseTreatmentIncidenceDiagnosis of Neuroendocrine TumorsMalignanciesBronchialPatients With Progressive Carcinoid TumorsPeople with gastrointestinal carcinoid tumorsCauses Gastrointestinal Carcinoid TumorsSomatostatinAdrenalSmallMalignant tumorsAbdominalLymphIslet cellSurgery
Tract2
Syndrome12
Metastases1
  • But when an advanced tumor spreads (metastasizes) to the liver itself, the chemicals that are secreted by these metastases won't be degraded as efficiently before they reach the bloodstream. (epharmapedia.com)
Liver3
  • CHD was frequent among patients with CS, significantly associated with high liver tumour burden, and likely linked to the history of cardiovascular disease and longer time of CS. (ecancer.org)
  • Instead of secreting chemicals directly into the liver where the chemicals are processed and eliminated, the carcinoid lung tumors that secrete them do so much farther upstream. (epharmapedia.com)
  • On the other hand, the chemicals of carcinoid tumors in the intestine are secreted into blood that must first pass through the liver before reaching the rest of the body. (epharmapedia.com)
Symptoms2
Disease2
Serotonin13
Intestinal13
Metastatic disease9
Midgut3
NETS22
Hormones12
Clinical19
Octreotide9
Gastric10
Lymphoma2
  • These radiologic findings raised the concern not only for the presence of inflammatory bowel disease but also a likely separate malignancy such as a carcinoid tumor or lymphoma. (sages.org)
  • IAN CHAU, MD, a consultant medical oncologist at the Gastrointestinal and Lymphoma Units of The Royal Marsden NHS Foundation Trust in London and Surrey, United Kingdom, was the invited discussant of KEYNOTE-062. (ascopost.com)
Originate4
Primary tumor2
GIST2
  • Novartis has announced that Gleevec (imatinib mesylate) tablets, (known as Glivec (imatinib) outside the US, Canada and Israel), has been granted priority review status by the US Food and Drug Administration (FDA) as the first therapy to be reviewed for use after surgery in kit-positive gastrointestinal stromal tumors (GIST). (news-medical.net)
  • Recently, the U.S. Food and Drug Administration granted Breakthrough Therapy designation to acalabrutinib in chronic lymphocytic leukemia (CLL), accepted a new drug application for avapritinib in some types of gastrointestinal stromal tumors (GIST), and granted 501(k) clearance to market the. (ascopost.com)
Carcinoma5
Pulmonary carcinoid tumors3
Neuroendocrine cells3
Appendiceal4
Arise3
Treatment38
Incidence3
Diagnosis of Neuroendocrine Tumors2
Malignancies3
Bronchial1
Patients With Progressive Carcinoid Tumors1
  • Pazopanib significantly improved progression-free survival by 47% in patients with progressive carcinoid tumors, in a prospective randomized phase II trial presented at the 2019 ASCO Annual Meeting.1 "With these results, Alliance A021202 becomes the first randomized study to show that the vascular. (ascopost.com)
People with gastrointestinal carcinoid tumors1
  • In most cases, people with gastrointestinal carcinoid tumors don't have any symptoms until late in the disease. (mercy.com)
Causes Gastrointestinal Carcinoid Tumors1
  • Do We Know What Causes Gastrointestinal Carcinoid Tumors? (medlineplus.gov)
Somatostatin1
Adrenal5
Small24
Malignant tumors2
Abdominal5
Lymph2
Islet cell3
Surgery11