Ganglia
Retinal Ganglion Cells
Neurons of the innermost layer of the retina, the internal plexiform layer. They are of variable sizes and shapes, and their axons project via the OPTIC NERVE to the brain. A small subset of these cells act as photoreceptors with projections to the SUPRACHIASMATIC NUCLEUS, the center for regulating CIRCADIAN RHYTHM.
Ganglia, Spinal
Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.
Basal Ganglia
Ganglia, Sympathetic
Ganglia, Autonomic
Clusters of neurons and their processes in the autonomic nervous system. In the autonomic ganglia, the preganglionic fibers from the central nervous system synapse onto the neurons whose axons are the postganglionic fibers innervating target organs. The ganglia also contain intrinsic neurons and supporting cells and preganglionic fibers passing through to other ganglia.
Trigeminal Ganglion
Ganglia, Parasympathetic
Ganglia, Sensory
Stellate Ganglion
Spiral Ganglion
Nodose Ganglion
Ganglia, Invertebrate
Clusters of neuronal cell bodies in invertebrates. Invertebrate ganglia may also contain neuronal processes and non-neuronal supporting cells. Many invertebrate ganglia are favorable subjects for research because they have small numbers of functional neuronal types which can be identified from one animal to another.
Basal Ganglia Diseases
Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
Neurons
Retina
The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.
Geniculate Ganglion
Optic Nerve
The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.
Action Potentials
Autonomic Fibers, Preganglionic
NERVE FIBERS which project from the central nervous system to AUTONOMIC GANGLIA. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the SPINAL CORD, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in SYNAPSES or continue through the SPLANCHNIC NERVES to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the BRAIN STEM and sacral spinal cord. In both divisions the principal transmitter is ACETYLCHOLINE but peptide cotransmitters may also be released.
Rats, Sprague-Dawley
Amacrine Cells
Sensory Receptor Cells
Optic Nerve Injuries
Injuries to the optic nerve induced by a trauma to the face or head. These may occur with closed or penetrating injuries. Relatively minor compression of the superior aspect of orbit may also result in trauma to the optic nerve. Clinical manifestations may include visual loss, PAPILLEDEMA, and an afferent pupillary defect.
Basal Ganglia Hemorrhage
Chick Embryo
Cell Count
Axotomy
Nerve Growth Factors
Synapses
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Electrophysiology
Globus Pallidus
Hypogastric Plexus
Axonal Transport
Immunohistochemistry
Membrane Potentials
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
Visual Pathways
Autonomic Fibers, Postganglionic
Cats
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Synaptic Transmission
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Glaucoma
An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
Satellite Cells, Perineuronal
Transcription Factor Brn-3A
Hexamethonium Compounds
Cells, Cultured
Nerve Fibers
Neurites
In tissue culture, hairlike projections of neurons stimulated by growth factors and other molecules. These projections may go on to form a branched tree of dendrites or a single axon or they may be reabsorbed at a later stage of development. "Neurite" may refer to any filamentous or pointed outgrowth of an embryonal or tissue-culture neural cell.
Substance P
Transcription Factor Brn-3B
Calcitonin Gene-Related Peptide
Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Ganglionic Blockers
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
In Situ Hybridization
Superior Colliculi
Rod Opsins
Patch-Clamp Techniques
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
Dendrites
Basal Ganglia Cerebrovascular Disease
A pathological condition caused by impaired blood flow in the basal regions of cerebral hemispheres (BASAL GANGLIA), such as INFARCTION; HEMORRHAGE; or ISCHEMIA in vessels of this brain region including the lateral lenticulostriate arteries. Primary clinical manifestations include involuntary movements (DYSKINESIAS) and muscle weakness (HEMIPARESIS).
Photic Stimulation
Autonomic Nerve Block
Leeches
Guinea Pigs
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Aplysia
Herpes Simplex
A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
Horseradish Peroxidase
Tyrosine 3-Monooxygenase
Tetrodotoxin
Vagus Nerve
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Virus Latency
The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.
Neuropeptides
Nociceptors
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
Sciatic Nerve
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Neuroglia
The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.
Enteric Nervous System
Two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. (From Kandel, Schwartz, and Jessel, Principles of Neural Science, 3d ed, p766)
Disease Models, Animal
Neural Crest
The two longitudinal ridges along the PRIMITIVE STREAK appearing near the end of GASTRULATION during development of nervous system (NEURULATION). The ridges are formed by folding of NEURAL PLATE. Between the ridges is a neural groove which deepens as the fold become elevated. When the folds meet at midline, the groove becomes a closed tube, the NEURAL TUBE.
Nervous System
Models, Neurological
Choline O-Acetyltransferase
Spinal Cord
TRPV Cation Channels
Cranial Nerves
Urodela
Transcription Factor Brn-3
Retinal Bipolar Cells
Receptors, Purinergic P2X3
A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.
Putamen
Macaca fascicularis
Peripheral Nervous System
The nervous system outside of the brain and spinal cord. The peripheral nervous system has autonomic and somatic divisions. The autonomic nervous system includes the enteric, parasympathetic, and sympathetic subdivisions. The somatic nervous system includes the cranial and spinal nerves and their ganglia and the peripheral sensory receptors.
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Nerve Degeneration
Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
Vision, Ocular
Neurofilament Proteins
Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal element in nerve axons and dendrites. They consist of three distinct polypeptides, the neurofilament triplet. Types I, II, and IV intermediate filament proteins form other cytoskeletal elements such as keratins and lamins. It appears that the metabolism of neurofilaments is disturbed in Alzheimer's disease, as indicated by the presence of neurofilament epitopes in the neurofibrillary tangles, as well as by the severe reduction of the expression of the gene for the light neurofilament subunit of the neurofilament triplet in brains of Alzheimer's patients. (Can J Neurol Sci 1990 Aug;17(3):302)
Gene Expression Regulation, Developmental
Rats, Wistar
Neurotrophin 3
Brain-Derived Neurotrophic Factor
Rana catesbeiana
Cell Survival
Subthalamic Nucleus
Central Nervous System
Peripheral Nerves
The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
Ciliary Body
Eye
Nervous System Physiological Phenomena
Myenteric Plexus
One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)
Magnetic Resonance Imaging
Sodium Channels
Virus Activation
The mechanism by which latent viruses, such as genetically transmitted tumor viruses (PROVIRUSES) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. It may be effected by various endogenous and exogenous stimuli, including B-cell LIPOPOLYSACCHARIDES, glucocorticoid hormones, halogenated pyrimidines, IONIZING RADIATION, ultraviolet light, and superinfecting viruses.
Neural Conduction
Tubocurarine
Nephropidae
Optic Chiasm
The X-shaped structure formed by the meeting of the two optic nerves. At the optic chiasm the fibers from the medial part of each retina cross to project to the other side of the brain while the lateral retinal fibers continue on the same side. As a result each half of the brain receives information about the contralateral visual field from both eyes.
Hyperalgesia
Retinal Cone Photoreceptor Cells
Photosensitive afferent neurons located primarily within the FOVEA CENTRALIS of the MACULA LUTEA. There are three major types of cone cells (red, blue, and green) whose photopigments have different spectral sensitivity curves. Retinal cone cells operate in daylight vision (at photopic intensities) providing color recognition and central visual acuity.
Retinal Degeneration
A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
Neurotransmitter Agents
Histocytochemistry
Cochlea
Herpesvirus 1, Human
The type species of SIMPLEXVIRUS causing most forms of non-genital herpes simplex in humans. Primary infection occurs mainly in infants and young children and then the virus becomes latent in the dorsal root ganglion. It then is periodically reactivated throughout life causing mostly benign conditions.
Brachyura
Microelectrodes
Acetylcholine
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Sympathetic Nervous System
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
Oculomotor Nerve
The 3d cranial nerve. The oculomotor nerve sends motor fibers to the levator muscles of the eyelid and to the superior rectus, inferior rectus, and inferior oblique muscles of the eye. It also sends parasympathetic efferents (via the ciliary ganglion) to the muscles controlling pupillary constriction and accommodation. The motor fibers originate in the oculomotor nuclei of the midbrain.
Nerve Endings
Branch-like terminations of NERVE FIBERS, sensory or motor NEURONS. Endings of sensory neurons are the beginnings of afferent pathway to the CENTRAL NERVOUS SYSTEM. Endings of motor neurons are the terminals of axons at the muscle cells. Nerve endings which release neurotransmitters are called PRESYNAPTIC TERMINALS.
Aminobutyrates
Neural Inhibition
Nerve Growth Factor
Visual Fields
Retrograde Degeneration
Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.
Fluorescent Antibody Technique, Indirect
A form of fluorescent antibody technique commonly used to detect serum antibodies and immune complexes in tissues and microorganisms in specimens from patients with infectious diseases. The technique involves formation of an antigen-antibody complex which is labeled with fluorescein-conjugated anti-immunoglobulin antibody. (From Bennington, Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Schwann Cells
Glossopharyngeal Nerve
The 9th cranial nerve. The glossopharyngeal nerve is a mixed motor and sensory nerve; it conveys somatic and autonomic efferents as well as general, special, and visceral afferents. Among the connections are motor fibers to the stylopharyngeus muscle, parasympathetic fibers to the parotid glands, general and taste afferents from the posterior third of the tongue, the nasopharynx, and the palate, and afferents from baroreceptors and CHEMORECEPTOR CELLS of the carotid sinus.
NAV1.8 Voltage-Gated Sodium Channel
Spinal Nerves
Parasympathetic Nervous System
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
Sympathectomy
Rabbits
Microscopy, Electron
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Hexamethonium
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Muscarine
Corpus Striatum
Striped GRAY MATTER and WHITE MATTER consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the THALAMUS in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The WHITE MATTER is the INTERNAL CAPSULE.
Ocular Hypertension
Photoreceptor Cells
Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade.
Thalamus
Acetylcholinesterase
Photoreceptor Cells, Vertebrate
Carbocyanines
Receptors, Nerve Growth Factor
Parkinson Disease
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Optic Nerve Diseases
Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
Dopamine
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
Fluorescent Dyes
Nerve Net
A meshlike structure composed of interconnecting nerve cells that are separated at the synaptic junction or joined to one another by cytoplasmic processes. In invertebrates, for example, the nerve net allows nerve impulses to spread over a wide area of the net because synapses can pass information in any direction.
Serotonin
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Neuralgia
Receptors, Nicotinic
One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
Celiac Plexus
Simplexvirus
Physostigmine
Interneurons
Transcription Factor Brn-3C
Herpesvirus 3, Human
Substantia Nigra
Adaptation, Ocular
Dose-Response Relationship, Drug
Mechanoreceptors
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Mice, Transgenic
Caudate Nucleus
Microscopy, Confocal
Spinal Nerve Roots
Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.
Octopamine
An alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates.
Early specification of sensory neuron fate revealed by expression and function of neurogenins in the chick embryo. (1/953)
The generation of sensory and autonomic neurons from the neural crest requires the functions of two classes of basic helix-loop-helix (bHLH) transcription factors, the Neurogenins (NGNs) and MASH-1, respectively (Fode, C., Gradwohl, G., Morin, X., Dierich, A., LeMeur, M., Goridis, C. and Guillemot, F. (1998) Neuron 20, 483-494; Guillemot, F., Lo, L.-C., Johnson, J. E., Auerbach, A., Anderson, D. J. and Joyner, A. L. (1993) Cell 75, 463-476; Ma, Q., Chen, Z. F., Barrantes, I. B., de la Pompa, J. L. and Anderson, D. J. (1998 Neuron 20, 469-482). We have cloned two chick NGNs and found that they are expressed in a subset of neural crest cells early in their migration. Ectopic expression of the NGNs in vivo biases migrating neural crest cells to localize in the sensory ganglia, and induces the expression of sensory neuron-appropriate markers in non-sensory crest derivatives. Surprisingly, the NGNs can also induce the expression of multiple pan-neuronal and sensory-specific markers in the dermomyotome, a mesodermal derivative. Taken together, these data suggest that a subset of neural crest cells may already be specified for a sensory neuron fate early in migration, as a consequence of NGN expression. (+info)Rhythmic swimming activity in neurones of the isolated nerve cord of the leech. (2/953)
1. Repeating bursts of motor neurone impulses have been recorded from the nerves of completely isolated nerve cords of the medicinal leech. The salient features of this burst rhythm are similar to those obtained in the semi-intact preparation during swimming. Hence the basic swimming rhythm is generated by a central oscillator. 2. Quantitative comparisons between the impulse patterns obtained from the isolated nerve cord and those obtained from a semi-intact preparation show that the variation in both dorsal to ventral motor neurone phasing and burst duration with swim cycle period differ in these two preparations. 3. The increase of intersegmental delay with period, which is a prominent feature of swimming behaviour of the intact animal, is not seen in either the semi-intact or isolated cord preparations. 4. In the semi-intact preparation, stretching the body wall or depolarizing an inhibitory motor neurone changes the burst duration of excitatory motor neurones in the same segment. In the isolated nerve cord, these manipulations also change the period of the swim cycle in the entire cord. 5. These comparisons suggest that sensory input stabilizes the centrally generated swimming rhythm, determines the phasing of the bursts of impulses from dorsal and ventral motor neurones, and matches the intersegmental delay to the cycle period so as to maintain a constant body shape at all rates of swimming. (+info)Physiological properties and receptive fields of mechanosensory neurones in the head ganglion of the leech: comparison with homologous cells in segmental ganglia. (3/953)
A study of the head ganglion of the leech was made to compare the properties of specific sensory cells in this ganglion with those of homologous neurones in the segmental ganglia. 1. In the head ganglion, cells were identified that had electrical properties, sensory modalities and adaptation properties similar to those of touch (T), pressure (P) and nociceptive (N) cells in the segmental ganglia. The cell bodies of these neurones were situated in characteristics positions that could be correlated with those in the segmental ganglia. Several lines of evidence suggested that they were primary sensory neurones. Fewer T, P and N neurones were identified in the head ganglion than would be expected from its six constituent segmental ganglia. 2. The receptive fields of identified T, P and N cells were situated on the external surface of the head and the interior of the mouth with considerable overlap. They were generally smaller in size than those situated on the main part of the body. The receptive fields were also displaced anteriorly so that some of them were situated in segments anterior to those of the innervating cells. 3. The morphology of the sensory cells in the head ganglion was studied by intracellular injection of horseradish perioxidase. The general branching characteristics of the cells and the structural appearance of their processes resembled those of homologous cells in the segmental ganglia. However, the routes taken to the periphery by some of the cells were not constant from head ganglion to head ganglion. This variability was confirmed by electrophysiological evidence, and differed from the constancy seen in segmental sensory cells. (+info)Receptive fields, geometry and conduction block of sensory neurones in the central nervous system of the leech. (4/953)
1. In segmental ganglia of the leech, the cutaneous mechanosensory neurones responding to to touch innervated the skin of their own segment and of part of the anterior and posterior adjacent segments. Each touch receptive field could be divided into three non-overlapping areas: a central part innervated by the branches of the cell which ran in the nerve roots of the ganglion containing the cell body, and anterior and posterior parts innervated by its branches which ran in the nerve roots of the anterior and posterior adjacent ganglia. 2. Impulses originating from the anterior and posterior parts of the receptive fields were susceptible to conduction block within the central nervous system when the touch cells fired repetitively at frequencies that could readily be elicited with weak mechanical stimulation. In contrast, impulses originating from the central part of the receptive fields were less susceptible to block. 3. The morphology of touch cells revealed by intracellular injection of horseradish peroxidase suggested that conduction block occurred at specific bifurcation points where small cell processes joined the main process. Different physiological experiments supported this conclusion. 4. In some touch cells, bifurcation points with particularly low safety margins of conduction operated as low-pass filters, limiting the frequency of impulses capable of invading certain branches. 5. The results suggest that mechanical stimuli which would likely be encountered by the animal can lead to conduction block within its central nervous system and as a result modify its integrative activities. (+info)Dopaminergic synapses mediate neuronal changes in an analogue of operant conditioning. (5/953)
Feeding behavior in Aplysia can be modified by operant conditioning in which contingent reinforcement is conveyed by the esophageal nerve (E n.). A neuronal analogue of this conditioning in the isolated buccal ganglia was developed by using stimulation of E n. as an analogue of contingent reinforcement. Previous studies indicated that E n. may release dopamine. We used a dopamine antagonist (methylergonovine) to investigate whether dopamine mediated the enhancement of motor patterns in the analogue of operant conditioning. Methylergonovine blocked synaptic connections from the reinforcement pathway and the contingent-dependent enhancement of the reinforced pattern. These results suggest that dopamine mediates at least part of the neuronal modifications induced by contingent reinforcement. (+info)Detection of caprine herpesvirus 1 in sacral ganglia of latently infected goats by PCR. (6/953)
A study of the latency of caprine herpesvirus 1 (CpHV.1) was carried out with four latently infected goats. Three goats were treated with dexamethasone and euthanized after 4 and 6 days. PCR and virus isolation allowed us to detect CpHV.1 only in the third and fourth sacral ganglia of the two animals euthanized 6 days after the start of treatment. (+info)Extraventricular neurocytoma with ganglionic differentiation associated with complex partial seizures. (7/953)
We report an unusual case of extraventricular ("cerebral") neurocytoma with ganglion cells located in the right temporal lobe in a 9-year-old girl with complex partial seizures and precocious puberty. CT showed a calcified mass with central cystic zones. MR imaging showed a markedly hyperintense predominately solid tumor on both T1- and T2-weighted images, without appreciable contrast enhancement. Cerebral neurocytomas are histologically benign and radical surgery is curative; they should be included in the differential diagnosis of temporal lobe tumors in children. (+info)An analysis of herpes simplex virus gene expression during latency establishment and reactivation. (8/953)
In order to facilitate an analysis of the pattern of herpes simplex virus gene expression during latency establishment and reactivation, recombinant viruses containing the lacZ reporter gene under control of either the immediate early 110 (IE110) promoter or the latency-associated promoter have been constructed. Histochemical staining of ganglia taken from mice infected with these viruses allows for the rapid identification and quantification of sensory neurones in which these two promoters are active. Using the mouse ear model, this study demonstrates that, during the establishment of latency in vivo, IE110 promoter activity is only detectable in ganglia which provide innervation to the site of virus inoculation. Latency, however, is efficiently established not only in these ganglia, but also in adjacent ganglia whose neurones do not innervate the ear, and in which there was no evidence of IE110 expression during the acute phase of infection. This implies that replication-competent virus can efficiently establish latency in the absence of detectable IE110 expression. In addition, it has been possible to investigate viral gene expression in neurones following ganglionic explant culture by monitoring IE110 promoter-driven lacZ expression within reactivating neurones. This study shows that virus can be reactivated from all latently infected ganglia, but that reactivation appears to be more efficient from ganglia which provide innervation to the site of infection. The implications of these results for the mechanisms involved in latency establishment and reactivation are discussed. (+info)Difference between revisions of The Central Ganglion - ZineWiki - the history and culture of zines, independent media and the...
Peripheral Ganglia - Human Anatomy
The Central Ganglion: 2009
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Peripheral ganglia and the eye : a connection tracing study</em>...
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Spontaneous activity in the statoacoustic ganglion of the chicken embryo<...
Abstract 18522: Atrial Ganglionated Plexus Stimulation Prevents Myocardial Ischemia Reperfusion Arrhythmias by Preserving...
Distribution of NADPH-diaphorase and nitric oxide synthase-containing neurons in the intramural ganglia of guinea pig urinary...
Excitation evoked by FMRFamide and FLRFamide in the heart of Buccinum undatum and evidence for inositol 1,4,5-trisphosphate as...
Peripheral ganglia in healthy rats as target structures for the evaluation of PSMA imaging agents | BMC Cancer | Full Text
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THE DISTRIBUTION OF SEVERAL AMINO ACIDS IN SPECIFIC GANGLIA AND NERVE BUNDLES OF THE LOBSTER<...
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Neuropeptides, amines and amino acids in an elementary insect ganglion: functional and chemical anatomy of the unfused...
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Celiac ganglia
They are sometimes referred to as the semilunar ganglia or the solar ganglia. The celiac ganglion is part of the sympathetic ... The celiac ganglia or coeliac ganglia are two large irregularly shaped masses of nerve tissue in the upper abdomen. Part of the ... The main preganglion neurotransmitter of the celiac ganglion is acetylcholine, yet the celiac ganglion-mesenteric complex also ... the two celiac ganglia are the largest ganglia in the ANS, and they innervate most of the digestive tract. They have the ...
Parasympathetic ganglia
... pterygopalatine ganglion, submandibular ganglion) glossopharyngeal nerve (otic ganglion) vagus nerve (no named ganglion) pelvic ... Parasympathetic ganglia are the autonomic ganglia of the parasympathetic nervous system. Most are small terminal ganglia or ... Some ganglia also carry special sensory fibers (SVA) for taste sensation. oculomotor nerve (ciliary ganglion) facial nerve ( ... These paired ganglia supply all parasympathetic innervation to the head and neck. ciliary ganglion (sphincter pupillae, ciliary ...
Lumbar ganglia
The lumbar ganglia are paravertebral ganglia located in the inferior portion of the sympathetic trunk. The lumbar portion of ... Paravertebral ganglia are divided into cervical, thoracic, lumbar, and sacral ganglia. Each controls different glands and ... Superiorly, it is continuous with thoracic sympathetic ganglion and inferiorly continuous with sacral sympathetic ganglion. ... The upper two lumbar ganglia (L1 and L2) of the sympathetic chain also give rise to the lumbar splanchnic nerves. Splanchnic ...
Ganglia (software)
Free and open-source software portal Official website Ganglia (software) on SourceForge "Ganglia". Freecode. Wikimedia Ganglia ... "Release 3.7.2". Ganglia Monitoring System Wikimedia Commons has media related to Ganglia (software). ... The ganglia system comprises two unique daemons, a PHP-based web front-end, and a few other small utility programs. Gmond is a ... Therefore, the Ganglia web front-end should run on a fairly powerful, dedicated machine if it presents a large amount of data. ...
Sacral ganglia
The sacral ganglia are paravertebral ganglia of the sympathetic trunk.:39 As the sympathetic trunk heads inferiorly down the ... Near the coccyx, the right and left sympathetic trunks join to form the ganglion impar. The sacral ganglia innervate blood ... There are generally four or five sacral ganglia. In addition to gray rami communicantes, the ganglia send off sacral splanchnic ... v t e (Articles with TA98 identifiers, Autonomic ganglia, All stub articles, Neuroanatomy stubs). ...
Segmental ganglia
The segmental ganglia (singular: s. ganglion) are ganglia of the annelid and arthropod central nervous system that lie in the ... The ventral nerve cord itself is a chain of ([Metamerism (biology),metamerism ganglia, some compressed. Smarandache-Wellmann, ...
Enteric ganglia
... may refer to: Submucous plexus Myenteric plexus This disambiguation page lists articles associated with the ... title Enteric ganglia. If an internal link led you here, you may wish to change the link to point directly to the intended ...
Prevertebral ganglia
... (or collateral ganglia, or preaortic ganglia) lie between the sympathetic ganglia and the target organ. ... the celiac ganglia (which can include the aorticorenal ganglion), 2. superior mesenteric ganglia, and 3. inferior mesenteric ... Similar to the paravertebral ganglia, the prevertebral ganglia are the nodules where preganglionic neurons synapse with their ... The nerves that synapse in the prevertebral ganglia innervate the pelvic viscera. Some of the targets present in the pelvic ...
Basal ganglia
The basal ganglia are situated at the base of the forebrain and top of the midbrain. Basal ganglia are strongly interconnected ... Basal ganglia disease is a group of movement disorders that result from either excessive output from the basal ganglia to the ... The term ganglia is a misnomer: In modern usage, neural clusters are called "ganglia" only in the peripheral nervous system; in ... The International Basal Ganglia Society (IBAGS) informally considers the basal ganglia to be made up of the striatum, the ...
Cervical ganglia
The inferior ganglion may be fused with the first thoracic ganglion to form a single structure, the stellate ganglion. - ... The cervical ganglion has three paravertebral ganglia: superior cervical ganglion (largest) - adjacent to C2 & C3; ... Unlike all other ganglia, the medial branches of the cervical ganglia are 95% postganglionic axons. Muscles, arteries and ... The cervical ganglia are paravertebral ganglia of the sympathetic nervous system. Preganglionic nerves from the thoracic spinal ...
Sympathetic ganglia
The sympathetic ganglia, or paravertebral ganglia are autonomic ganglia, of the sympathetic nervous system. Ganglia are 20,000 ... These include the celiac ganglia, superior mesenteric ganglia, and inferior mesenteric ganglia. Schematic Illustration of ... The chain extends from the upper neck down to the coccyx, forming the unpaired coccygeal ganglion. Each ganglion within this ... There are usually 22-23 pairs of these ganglia: 3 in the cervical region (cervical ganglia), 11 in the thoracic region (note ...
Ganglia (disambiguation)
The term ganglia may refer to: Plural form of ganglion, a cluster of neurons Lymph node Ganglion cyst Ganglia (software), a ... Look up ganglia in Wiktionary, the free dictionary. ... page lists articles associated with the title Ganglia. If an ... scalable distributed monitoring system for high-performance computing systems Ganglion (disambiguation) This disambiguation ...
Thoracic ganglia
The thoracic ganglia are paravertebral ganglia. The thoracic portion of the sympathetic trunk typically has 12 thoracic ganglia ... Sympathetic connections of the ciliary and superior cervical ganglia. v t e (Articles with TA98 identifiers, Autonomic ganglia ... Emerging from the ganglia are thoracic splanchnic nerves (the cardiopulmonary, the greater, lesser, and least splanchnic nerves ... the ganglia of the thoracic sympathetic trunk have both white and gray rami communicantes. The white rami communicantes carry ...
Primate basal ganglia
It has a dual role as a regulator of, and of being regulated by the basal ganglia. In the cortico-basal ganglia-thalamo- ... The primate central complex as one of the basal ganglia. In The Basal Ganglia III Bernardi, G. et al. (eds) pp. 177-186. Plenum ... The basal ganglia form a major brain system in all species of vertebrates, but in primates (including humans) there are special ... 2004) to propose that the complex be linked in a way or another to the basal ganglia system. A review on its role in the system ...
Cranial nerve ganglia
... ciliary ganglion pterygopalatine ganglion otic ganglion submandibular ganglion trigeminal ganglion (CN V) geniculate ganglion ( ... CN VII) spiral ganglion (CN VIII) vestibular ganglion aka Scarpa's ganglion (CN VIII) superior ganglion of glossopharyngeal ... In neuroanatomy, the cranial nerve ganglia are ganglia of certain cranial nerves. They can be parasympathetic or sensory. All ... nerve inferior ganglion of glossopharyngeal nerve superior ganglion of vagus nerve inferior ganglion of vagus nerve Purves, ...
Basal ganglia disease
Blepharospasm may come from abnormal functioning of the brain's basal ganglia. Many disorders of the basal ganglia are due to ... Though motor disorders are the most common associated with the basal ganglia, recent research shows that basal ganglia ... primarily in the basal ganglia. About 0.3-1.5% of people have asymptomatic basal ganglia calcifications. Blepharospasm is any ... Basal ganglia disease is a group of physical problems that occur when the group of nuclei in the brain known as the basal ...
Ganglion
Ganglia often interconnect with other ganglia to form a complex system of ganglia known as a plexus. Ganglia provide relay ... Among vertebrates there are three major groups of ganglia: Dorsal root ganglia (also known as the spinal ganglia) contain the ... Cranial nerve ganglia contain the cell bodies of cranial nerve neurons. Autonomic ganglia contain the cell bodies of autonomic ... A pseudoganglion looks like a ganglion, but only has nerve fibers and has no nerve cell bodies. Ganglia are primarily made up ...
Suboesophageal ganglion
The suboesophageal ganglion (acronym: SOG; synonym: subesophageal ganglion) of arthropods and in particular insects is part of ... and to the first thoracic ganglion (or protothoracic ganglion). Its nerves innervate the sensory organs and muscles of the ... Neurons in the suboesophageal ganglion control movement of the head and neck as well. It is composed of three pairs of fused ... As part of the ventral nerve cord, it is connected (via pairs of connections) to the brain (or supraoesophageal ganglion) ...
Ganglion (disambiguation)
Ganglion may also refer to: Ganglion cyst Ganglion (band), a musical act from Calgary, Alberta, Canada Ganglia (disambiguation ... Look up Ganglion or ganglion in Wiktionary, the free dictionary. Ganglion is a biological tissue mass, most commonly a mass of ... This disambiguation page lists articles associated with the title Ganglion. If an internal link led you here, you may wish to ...
Aorticorenal ganglion
... and inferior mesenteric ganglia. This is distinct from the celiac ganglia. However, they are part of the preaortic ganglia. ... The aorticorenal ganglion is composed of the superior mesenteric, renal, ... and synapses in the celiac ganglion before proceeding onto the foregut. Below this the lesser splanchnic nerve arises from T10- ... T11, leaves the sympathetic chain and synapses at the aorticorenal ganglion before going onto also supply the kidney and upper ...
Ganglion impar
Below, the two pelvic sympathetic trunks converge, and end on the front of the coccyx in a small ganglion, the ganglion impar, ... also known as azygos or ganglion of Walther. A study found that in some cases a single injection of nerve block at the ganglion ... ganglion impar - azygos. Foye P, Buttaci C, Stitik T, Yonclas P (2006). "Successful injection for coccyx pain". Am J Phys Med ... Munir MA, Zhang J, Ahmad M. (2004) "A modified needle-inside-needle technique for the ganglion impar block." Can J Anaesth. ...
Stellate ganglion
The stellate ganglion (or cervicothoracic ganglion) is a sympathetic ganglion formed by the fusion of the inferior cervical ... The stellate ganglion is relatively big (10-12 x 8-20 mm) compared to much smaller thoracic, lumbar and sacral ganglia, and is ... It is thought that anesthetic is spread along the paravertebral muscles to the stellate ganglion. Stellate ganglion block also ... ganglion, which exists in 80% of people. Sometimes, the second and the third thoracic ganglia are included in this fusion. ...
Inferior ganglion
... may refer to: Inferior cervical ganglion Inferior cervical sympathetic ganglion Inferior ganglion of vagus ... nerve Inferior ganglion of glossopharyngeal nerve Inferior mesenteric ganglion This disambiguation page lists articles ... associated with the title Inferior ganglion. If an internal link led you here, you may wish to change the link to point ...
Geniculate ganglion
The geniculate ganglion is one of several ganglia of the head and neck. Like the others, it is a bilaterally distributed ... The geniculate ganglion is an important surgical landmark near the internal auditory meatus. The geniculate ganglion may become ... much like the Dorsal root ganglion neurons relay signal to nuclei in the spinal cord. Via the geniculate ganglion, the facial ... do not synapse in the geniculate ganglion. Instead, the cells of the geniculate ganglion relay the signal to the appropriate ...
Vagus ganglion
A vagus ganglion (plural: vagus ganglia) is a small, elongated ganglion located between the esophagus and aorta. They mark the ... nervous system neuron ganglion "vagus nerve." Encyclopædia Britannica. Encyclopædia Britannica Online Academic Edition. ... Nervous ganglia of the torso, Vagus nerve, All stub articles, Neuroanatomy stubs). ...
Submandibular ganglion
The others are the otic ganglion, pterygopalatine ganglion, and ciliary ganglion). The submandibular ganglion is small and ... The submandibular ganglion (or submaxillary ganglion in older texts) is part of the human autonomic nervous system. It is one ... Like other parasympathetic ganglia of the head and neck, the submandibular ganglion is the site of synapse for parasympathetic ... Autonomic ganglia of the head and neck, Mandibular nerve, Parasympathetic ganglia). ...
Trigeminal ganglion
A trigeminal ganglion (or Gasserian ganglion, or semilunar ganglion, or Gasser's ganglion) is the sensory ganglion at the base ... The otic ganglion and its branches. Trigeminal ganglion Trigeminal ganglion. Deep dissection. Superior view. This article ... The greater superficial petrosal nerve lies also underneath the ganglion. The ganglion receives, on its medial side, filaments ... The motor root runs in front of and medial to the sensory root, and passes beneath the ganglion; it leaves the skull through ...
Vestibular ganglion
The vestibular ganglion (also called Scarpa's ganglion) is the ganglion of the vestibular nerve. It is located inside the ... The ganglion contains the cell bodies of bipolar neurons whose peripheral processes form synaptic contact with hair cells of ... Sato H; Sando I; Takahashi H (September 1992). "Three-dimensional anatomy of human Scarpa's ganglion". Laryngoscope. 102 (9): ...
Mesenteric ganglion
... may refer to: inferior mesenteric ganglion superior mesenteric ganglion This disambiguation page lists ... articles associated with the title Mesenteric ganglion. If an internal link led you here, you may wish to change the link to ...
Ganglion cyst
... ganglion volar wrist ganglion volar retinaculum ganglion extensor retinaculum ganglion occult ganglion intraosseous ganglion ... the ganglion cyst is unrelated to the neural "ganglion" or "ganglion cell"; its etymology traces back to the ancient Greek ... Between 50 and 70% of all masses on the hand and wrist are expected to be ganglion cysts. Ganglion cysts most frequently occur ... Although most commonly found in the wrist, ganglion cysts also may occur in the foot. Ganglion cysts are "commonly observed in ...
Basal ganglia dysfunction: MedlinePlus Medical Encyclopedia
Basal ganglia dysfunction is a problem with the deep brain structures that help start and control movement. ... Basal ganglia dysfunction is a problem with the deep brain structures that help start and control movement. ... A common cause of the symptoms of basal ganglia dysfunction is chronic use of medicines used to treat schizophrenia. ... Damage to the basal ganglia cells may cause problems controlling speech, movement, and posture. This combination of symptoms is ...
Browsing by Subject "Basal Ganglia Diseases"
Stellate Ganglion Block a Potential Lifesaver in Severe PTSD
It is hypothesized that trauma leads to an increase in nerve growth factor in the stellate ganglion. This in turn leads to a ... Stellate ganglion blockade (SGB) "seems to significantly improve PTSD symptoms as well as significantly reduce or eliminate ... Cite this: Stellate Ganglion Block a Potential Lifesaver in Severe PTSD - Medscape - May 19, 2015. ...
The Hidden Life of the Basal Ganglia
The anatomy and physiology of the basal ganglia and their relation to brain and behavior, disorders and therapies, and ... The main task of the basal ganglia-a group of subcortical nuclei, located at the base of the brain-is to optimize and execute ... In this book, Hagai Bergman analyzes the anatomy and physiology of the basal ganglia, discussing their relation to brain and ... Focusing on studies of nonhuman primates and human basal ganglia and relying on system physiology and in vivo extra-cellular ...
Medical Definition of Basal ganglia
Browsing by Subject "Basal Ganglia Diseases"
Overview of salamander ganglion cell responses to natural images.
... insideretinal ganglion cellsnatural visual scenesnatural images dependsalamander ganglion cellsencoding natural imagesganglion ... B) Left: One of the 300 natural images, overlaid with the 3-sigma outline of the receptive field of a sample retinal ganglion ... Simple model for encoding natural images by retinal ganglion cells with nonlinear spatial integration ...
Basal ganglia volume and proximity to onset in presymptomatic Huntington disease
The results suggest that atrophy of the basal ganglia occurs gradually, beginning years before symptom onset. ... Basal ganglia volume and proximity to onset in presymptomatic Huntington disease Arch Neurol. 1996 Dec;53(12):1293-6. doi: ... Gene-positive subjects who were far from onset had smaller basal ganglia volumes than gene-negative subjects for all structures ... Gene-positive subjects who were close to onset had smaller volumes than gene-negative subjects for all basal ganglia structures ...
Ganglion Anatomy
... , Nerve Plexus Anatomy, Ganglion, Nerve Plexus. ... Ganglion Anatomy. Ganglion Anatomy Aka: Ganglion Anatomy, Nerve ... Ganglia, ganglion, Ganglionic, neural ganglion, a group of nerve cell, ganglia, Ganglion, GANGLION, Nervous system ganglion, ... spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. ... spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. ...
Ganglion Cyst Removal: Procedures, Risks, and Recovery
A ganglion cyst is a noncancerous lump that most commonly develops on the wrist or hand. It may be painful or restrict movement ... When a ganglion cyst presses on a nerve it can be painful. And depending on its location, a ganglion cyst may restrict movement ... A ganglion cyst removal does not guarantee that ganglion cysts will not return, and you may experience new cysts a few years ... Removal of severe ganglion cysts can be quite beneficial.. Some people with a ganglion cyst may never experience pain or ...
Wand: Ganglion Reef Album Review | Pitchfork
Accordingly, it moves, what makes Ganglion Reef so euphorically hypnotic is the way it translates bandleader Cory Hansons ... It seemingly depicts Ganglion Reef itself-an imaginary island that the members of Wand might just frequent from time to time, ... The insert that comes with Ganglion Reef, the debut album by Los Angeles Wand, is printed with the kind of map that might ... Plenty of new psych-rock albums are content to fill the signifier checklist and then just sit there, but Ganglion Reef is as ...
Basal Ganglia Pathophysiology | Lund University
Basal Ganglia Pathophysiologys profile in Lund University Research portal Description. The basal ganglia are a group of ... Loss or dysfunction of neurons within the basal ganglia cause some typical motor symptoms, such as poverty of movement ( ... is the most common neurodegenerative disease affecting the basal ganglia. The typical lesion in PD consists in a loss of ... Website: http://www.med.lu.se/english/expmed/research/basal_ganglia_pathophysiology ...
Basal Ganglia Neuronal Activity during Scanning Eye Movements in Parkinson's Disease | PLOS ONE
We conclude that a relatively large number of basal ganglia neurons are involved in eye motion control. Surprisingly, neurons ... The oculomotor role of the basal ganglia has been supported by extensive evidence, although their role in scanning eye ... Basal ganglia Is the Subject Area "Basal ganglia" applicable to this article? Yes. No. ... basal ganglia or cerebellum [4], [8], [24]. Therefore, in a subgroup of patients, we additionally studied the basal ganglia ...
SOLR-9880] Add Ganglia, Graphite and SLF4J metrics reporters - ASF JIRA
Ganglions
... Condition Basics. What are ganglions?. Ganglions are small sacs (cysts) filled with fluid that often appear as bumps ... Some ganglions can weaken your grip or affect joint motion. How are they diagnosed?. A ganglion can usually be diagnosed based ... How are ganglions treated?. Ganglions usually dont need treatment, and they often go away on their own. But treatment may be ... Most people with ganglions notice that the bumps appear suddenly. Bumps may be very small or bigger than a cherry. Ganglions ...
Grueneberg Ganglion Neurons Are Finely Tuned Cold Sensors | Journal of Neuroscience
Grueneberg Ganglion Neurons Are Finely Tuned Cold Sensors Message Subject (Your Name) has forwarded a page to you from Journal ... Grueneberg Ganglion Neurons Are Finely Tuned Cold Sensors. Andreas Schmid, Martina Pyrski, Martin Biel, Trese Leinders-Zufall, ... Grueneberg Ganglion Neurons Are Finely Tuned Cold Sensors. Andreas Schmid, Martina Pyrski, Martin Biel, Trese Leinders-Zufall, ... Grueneberg Ganglion Neurons Are Finely Tuned Cold Sensors. Andreas Schmid, Martina Pyrski, Martin Biel, Trese Leinders-Zufall ...
Nerve Cells from Spinal Ganglia | ClipArt ETC
Interaction of sensory and motor signals in the basal ganglia in health and disease | KTH
TRANSMISSION AND BLOCK IN SYMPATHETIC GANGLIA | Pharmacological Reviews
Basal ganglia calcification - Ontology Report - Rat Genome Database
The purinergic receptors 2X3 on spiral ganglion neurons enha... : NeuroReport
The purinergic receptors 2X3 on spiral ganglion neurons enhance the medial olivocochlear reflex in mice after long-term ... The purinergic receptors 2X3 on spiral ganglion neurons enhance the medial olivocochlear reflex in mice after long-term ... The purinergic receptors 2X3 on spiral ganglion neurons enhance the medial olivocochlear reflex in mice after long-term ... long-term moderate noise\r, medial olivocochlear\r, P2X\r, spiral ganglion neurons. ...
ganglia - NERDlogger.com
Orphanet: Hypomyelination with atrophy of basal ganglia and cerebellum
Longitudinal change in basal ganglia volume in patients with Huntington's disease | Neurology
Longitudinal change in basal ganglia volume in patients with Huntingtons disease. E. H. Aylward, Q. Li, O. C. Stine, N. Ranen ... Longitudinal change in basal ganglia volume in patients with Huntingtons disease. E. H. Aylward, Q. Li, O. C. Stine, N. Ranen ... Total basal ganglia volume was calculated by adding the volumes of the head of the caudate, putamen, and globus pallidus. ... Amount of basal ganglia change did not correlate significantly with QNE at time of initial imaging or duration of symptoms, ...
Ganglia Archives - IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)
Ultrasound Stimulations Induce Prolonged Depolarization and Fast Action Potentials in Leech Neurons https://www.embs.org/ojemb/wp-content/uploads/sites/20/2020/02/ojemb-gagraphic-2963474-e1582803092460-1.jpg 800 345 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB) IEEE Open Journal of Engineering in Medicine and Biology (OJEMB) //www.embs.org/ojemb/wp-content/uploads/sites/20/2022/06/ieee-ojemb-logo2x.png ...
Ganglion Cyst | Connecticut Children's
What is a Dorsal Wrist Ganglion Cyst?. A ganglion cyst (synovial cyst) is a fluid filled membrane that can occur around any ... Ganglion cysts are caused when normal joint fluid leaks out of the joint capsule due to a capsular injury (sprain) or due to a ... Wrist ganglion cysts will many times rupture on their own due to continued pressure to this area from activity approximately 60 ... This again can lead to recurrence of the ganglion cyst in about 50% of cases. If recurrence continues, surgical intervention ...
Strange Horizons - Podcast: Basal Ganglia By Lynne Sargent, Podcast read by Ciro Faienza
Proceedings of the workshop on Cerebellum, Basal Ganglia and Cortical Connections Unmasked in ...
Proceedings of the workshop on Cerebellum, Basal Ganglia and Cortical Connections Unmasked in Health and Disorder Held in Brno ... KW - Basal ganglia. KW - Dentate. KW - Striatum. KW - Imaging. KW - White matter. KW - Magnetic resonance spectroscopy. KW - ... Publications , Proceedings of the workshop on Cerebellum, Basal Ganglia and Cortical Connections Unmasked in .... ... TI - Proceedings of the workshop on Cerebellum, Basal Ganglia and Cortical Connections Unmasked in Health and Disorder Held in ...
NeuronsCerebellumRetinalStellate ganglion blocksRole of the basal gangliaStudying the basal gangliaDorsal ganglion cystSphenopalatine ganglion blockNerveParasympatheticStructuresAnatomyCyst removalCerebralCysts do notThalamusStimulationAtrophyOccipital lobesOccurNervesRetinaNervousTumorsVolarCalcificationCancerousBrainAutonomicSurgicallyAspirationScaphotrapezial jointSymptomsRecurrenceWrist and handMucousPathogenesisIncluding Parkinson's diseaseArthroscopicTendonArisesNonsurgicalDysfunctionJoint capsuleLumpTreatmentSymptomCervicalOccultInferior
Neurons11
- We conclude that a relatively large number of basal ganglia neurons are involved in eye motion control. (plos.org)
- The purinergic receptors 2X3 on spiral ganglion neurons enha. (lww.com)
- Our purpose was to study the expression of purinergic receptors 2X2 (P2X2) and purinergic receptors 2X3 (P2X3) in spiral ganglion neurons (SGNs), the afferent nerves of medial olivocochlear (MOC) reflex, after long-term moderate noise exposure, and its relationship with the enhancement of MOC reflex. (lww.com)
- Retinal ganglion cells (RGCs) are the neurons in the retina which directly project to the brain and transmit visual information along the optic nerve. (frontiersin.org)
- Cultured dissociated primary dorsal root ganglion neurons from adult horses enable study of axonal transport. (cam.ac.uk)
- Here we report the generation of primary neuronal dorsal root ganglia (DRG) cultures from adult horses: the mixed, dissociated cultures, containing neurons and glial cells, remained viable for at least 90 days. (cam.ac.uk)
- Diabetic Polyneuropathy: New Strategies to Target Sensory Neurons in Dorsal Root Ganglia. (bvsalud.org)
- Although the pathogenesis of DPN is complex, this review emphasizes the concept that hyperglycemia and metabolic stressors directly target sensory neurons in the dorsal root ganglia ( DRG ), leading to distal axonal degeneration. (bvsalud.org)
- No obvious histopathologies were observed after 24h treatment with any of the paclitaxel doses employed, but with 48 h treatment, paclitaxel damaged cochlear hair cells in a dose-dependent manner and also damaged auditory nerve fibers and spiral ganglion neurons (SGN) near the base of the cochlea. (cdc.gov)
- 1987. The influence of skeletal muscle on the electrical excitability of dorsal root ganglion neurons in culture. (cdc.gov)
- A part of the coeliac ganglion that is semidetached and contains sympathetic neurons that innervate the kidney. (cdc.gov)
Cerebellum5
- Proceedings of the workshop on Cerebellum, Basal Ganglia and Cortical Connections Unmasked in Health and Disorder Held in Brno, Czech Republic, October 17th, 2013. (muni.cz)
- N2 - The proceedings of the workshop synthesize the experimental, preclinical, and clinical data suggesting that the cerebellum, basal ganglia (BG), and their connections play an important role in pathophysiology of various movement disorders (like Parkinson's disease and atypical parkinsonian syndromes) or neurodevelopmental disorders (like autism). (muni.cz)
- These patients were noted to have variable degree of calcification in different parts of brain i.e., basal ganglia (42 cases), cerebellum (12 cases) and cerebral cortex (nine cases). (who.int)
- The premotor and sensory regions provide the input for planning to the basal ganglia and the cerebellum. (cdc.gov)
- There is usually preserved metabolism in the sensorimotor cortices, basal ganglia, occipital lobes, and cerebellum. (snmjournals.org)
Retinal8
- A) Schematic of the sequence of 300 natural images presented individually in a pseudo-random fashion for 200 ms each, with an inter-stimulus-interval of 800 ms. B) Left: One of the 300 natural images, overlaid with the 3-sigma outline of the receptive field of a sample retinal ganglion cell. (figshare.com)
- However, we unexpectedly detected a large number of cells in the inner nuclear layer expressing retinal ganglion cell (RGC)-specific markers (called displaced RGCs, dRGCs) when at least one allele of Gsk3α is expressed. (eneuro.org)
- Our study thus uncovers a unique role of GSK3 in controlling the production of ganglion cells in the inner nuclear layer, which correspond to dRGCs, a rare and poorly characterized retinal cell type. (eneuro.org)
- Interrestingly, we unexpectedly uncovered a unique role of GSK3s in controlling the genesis of retinal ganglion cells in the inner nuclear layer, which could correspond to a rare and poorly characterized retinal cell type. (eneuro.org)
- Therefore, our mouse models potentially offer a unique and powerful model system to study the visual function of displaced retinal ganglion cells in mammals. (eneuro.org)
- In the vertebrate retina, retinal ganglion cell (RGC) dendrites extend from the cell body and form synapses with nearby amacrine and bipolar cells. (pubpub.org)
- Solutions will be evaluated for establishment of a human PSC-derived in vitro retina model system that resembles the morphology of a healthy-native retina and is viable through formation of photoreceptor outer segments and/or long-term survival of retinal ganglion cells with extension of axonal processes. (nih.gov)
- Off-cone), and Retinal Ganglion Cells (identify at least three subtypes). (nih.gov)
Stellate ganglion blocks8
- Stellate ganglion blocks have been utilized for almost a century to treat a variety of medical conditions. (medscape.com)
- Today, stellate ganglion blocks are most commonly used in the diagnosis and treatment of sympathetically maintained pain in the head, neck, and upper extremity. (medscape.com)
- Stellate ganglion blocks have traditionally been performed blindly by palpating the anterior tubercle of the transverse process of C6 (Chassaignac tubercle) and directing a needle to the C6 transverse process while retracting the the carotid laterally. (medscape.com)
- Image-guided stellate ganglion blocks have the advantages of increased safety and accuracy compared with blind injections. (medscape.com)
- Stellate ganglion blocks are also used to see if blood flow can be improved in those patients with circulation problems related to vascular disease. (umms.org)
- Stellate ganglion blocks may be therapeutic (to relieve pain) and/or diagnostic (to determine the source of your pain). (umms.org)
- SHINGLES RELIEF: Sphenopalatine Ganglion (SPG) Blocks Offers Fast Relief for Herpes Zoster as does Stellate Ganglion Blocks. (sleepandhealth.com)
- Autonomic Blocks: Sphenopalatyine Ganglion Blocks and Stellate Ganglion Blocks can give amazing relief from the pain of a Herpes Zoster Episode. (sleepandhealth.com)
Role of the basal ganglia2
- In his unique, passionate style, Hagai Bergman takes the reader on a journey through his lifelong quest for understanding the fundamental role of the basal ganglia within the brain orchestra. (mit.edu)
- The oculomotor role of the basal ganglia has been supported by extensive evidence, although their role in scanning eye movements is poorly understood. (plos.org)
Studying the basal ganglia1
- Drawing on his forty years of studying the basal ganglia, Bergman presents new information on physiology and computational models, Parkinson's disease and other ganglia-related disorders, and such therapies as deep brain stimulation. (mit.edu)
Dorsal ganglion cyst2
- Typical appearance of dorsal ganglion cyst. (medscape.com)
- Surgery (open or arthroscopic) often becomes necessary, and current evidence suggests that arthroscopic ganglion excision is a practical and successful means of dorsal ganglion cyst removal. (medscape.com)
Sphenopalatine ganglion block3
- Schaffer J, Hunter B, Ball K, Weaver C. Noninvasive sphenopalatine ganglion block for acute headache in the emergency department: a randomized placebo-controlled trial. (aliem.com)
- PALM SPRINGS, California - A noninvasive, easy-to-administer sphenopalatine ganglion block relieves postdural puncture headache (PDPH) faster than an epidural blood patch in obstetric patients and has fewer adverse effects, new research shows. (medscape.com)
- The sphenopalatine ganglion block has been used successfully for other headaches, including migraines, for more than 100 years, without significant side effects. (medscape.com)
Nerve14
- Okada K, Miyake J, Kataoka T, Moritomo H, Murase T, Yoshikawa H. Median nerve neuropathy in the forearm due to recurrence of anterior wrist ganglion that originates from the scaphotrapezial joint: Case Report. (medscape.com)
- Ulnar Nerve Compression in Guyon's Canal by Ganglion Cyst. (medscape.com)
- together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. (fpnotebook.com)
- When a ganglion cyst presses on a nerve it can be painful. (healthline.com)
- This illustration shows nerve cells from spinal ganglia. (usf.edu)
- Compression of the median nerve can occur when a volar radial ganglion arises within the carpal canal. (medscape.com)
- [ 5 ] The ulnar nerve may also be compressed within the tunnel of Guyon when the ganglion presents on the ulnar side of the wrist. (medscape.com)
- Volar ganglia are commonly associated with the radioscaphoid and scaphotrapezial joints, with proximity to the palmar cutaneous branch of the median nerve and the median nerve itself. (medscape.com)
- Electron micrograph of Maize mosaic virus (MMV, Rhabdoviridae) in nerve ganglion of the insect vector Peregrinus maidis (planthopper, Hemiptera, Delphacidae). (cellimagelibrary.org)
- It's imperative to identify potential issues such as nerve sheath tumors or ganglion cysts with pre-op imaging beforehand. (aorn.org)
- VZV remains dormant in sensory-nerve ganglia and may be reactivated at a later time causing herpes zoster (i.e., shingles) -- a painful vesicular rash usually appearing in a dermatomal distribution of one or two sensory-nerve roots. (cdc.gov)
- His first project was to isolate nerve growth factor from sarcoma 180-a tumor which causes extreme nerve growth in spinal and sympathetic ganglia of the chick . (asu.edu)
- COLD SORE STAGES: #1 - LATENT - Here the cold sore herpes simplex virus is hiding in the nerve ganglia near the back of the jaw on the same side as your cold sore usually appears. (comixme.net)
- Your cold sore virus is now retreating back to the nerve ganglia area where it will sleep until the next opportunity. (comixme.net)
Parasympathetic2
- The sphenopalatine ganglion (SPG) is an extracranial parasympathetic ganglion with both sensory and autonomic fibers. (aliem.com)
- Which of the following ganglia are associated with the parasympathetic division of the autonomic nervous system? (easynotecards.com)
Structures8
- Basal ganglia dysfunction is a problem with the deep brain structures that help start and control movement. (medlineplus.gov)
- Focusing on studies of nonhuman primates and human basal ganglia and relying on system physiology and in vivo extra-cellular recording techniques, Bergman first describes the major brain structures that constitute the basal ganglia, the morphology of their cellular elements, their synaptic connectivity and their physiological function in health and disease. (mit.edu)
- After controlling for the subject's age at the time of the scan, significant correlations were found between volumes of all basal ganglia structures and years to onset. (nih.gov)
- Gene-positive subjects who were far from onset had smaller basal ganglia volumes than gene-negative subjects for all structures except globus pallidus. (nih.gov)
- The presence of calcium deposition affecting one or more structures of the basal ganglia. (mcw.edu)
- Amount of change in basal ganglia structures was not significantly correlated with neurologic symptom severity at the time of the initial imaging or duration of symptoms. (neurology.org)
- The activity of free moving rats was recorded in different structures of the cortico-basal ganglia circuit before and after an injection of a subanesthesic dose of ketamine (10mg/kg). (cun.es)
- The basal ganglia are a set of structures deep in the brain. (medlineplus.gov)
Anatomy4
- The anatomy and physiology of the basal ganglia and their relation to brain and behavior, disorders and therapies, and philosophy of mind and moral values. (mit.edu)
- In this book, Hagai Bergman analyzes the anatomy and physiology of the basal ganglia, discussing their relation to brain and behavior, to disorders and therapies, and even to moral values. (mit.edu)
- These images are a random sampling from a Bing search on the term "Ganglion Anatomy. (fpnotebook.com)
- Understanding the surrounding anatomy of the stellate ganglion is critical for an effective block and to avoid serious and even life-threatening complications. (medscape.com)
Cyst removal5
- During a ganglion cyst removal, a doctor removes the cyst capsule or stalk to completely remove the cyst. (healthline.com)
- Ganglion cyst removal is usually an outpatient procedure and may be performed under local or general anesthesia. (healthline.com)
- What are the benefits of ganglion cyst removal? (healthline.com)
- As with any surgery, ganglion cyst removal can cause infection. (healthline.com)
- Most likely, you'll heal quickly and without difficulty after a ganglion cyst removal. (healthline.com)
Cerebral2
- At the subcortical level, an involvement of the basal ganglia during scanning EM was suggested by early research using regional cerebral blood flow in healthy controls and schizophrenic patients [7] . (plos.org)
- H-ABC is diagnosed on the basis of the distinctive MRI findings of diffuse but partial hypomyelination of the cerebral hemispheres, mild to severe cerebellar atrophy and atrophy of the basal ganglia. (orpha.net)
Cysts do not1
- Many ganglion cysts do not require treatment. (orthoinfo.org)
Thalamus2
- Studies show the importance of the basal ganglia and thalamus in memory, attention, selection and monitoring of information. (bvsalud.org)
- Shaheen H , Melnik R, Singh P. Deep Brain Stimulation with a Computational Model for the Cortex-Thalamus-Basal-Ganglia System and Network Dynamics of Neurological Disorders. (wjgnet.com)
Stimulation5
- Dorsal root ganglion (DRG) stimulation is an emerging technique that may have a role in the treatment in many pain conditions. (cns.org)
- Dorsal root ganglion stimulation appears to be a valuable addition to the armamentarium against chronic pain. (cns.org)
- Dorsal root ganglion stimulation is similarly based upon the gate theory of pain but with more precision as it strictly targets the dorsal root ganglion. (cureus.com)
- We present a case of a patient with chronic pancreatitis who obtained 80% abdominal pain relief for two years after undergoing dorsal root ganglion stimulation. (cureus.com)
- Dopamine physiology in the basal ganglia of male zebra finches during social stimulation. (ucsf.edu)
Atrophy4
- The results suggest that atrophy of the basal ganglia occurs gradually, beginning years before symptom onset. (nih.gov)
- Article abstract-Cross-sectional MRI studies demonstrating an association between caudate atrophy and symptom severity and duration of symptoms in patients with Huntington's disease (HD) have been assumed to reflect longitudinal changes in basal ganglia, but such neuropathologic progression has never been directly demonstrated. (neurology.org)
- This is the first longitudinal MRI study to document progressive basal ganglia atrophy in HD, and suggests that quantitative neuroimaging with serial MRI may be useful in monitoring effectiveness of potential treatments. (neurology.org)
- In addition, demonstration of greater rate of basal ganglia atrophy in patients with earlier symptom onset suggests that treatment effects may be more quickly observed in this subgroup of patients than in the general HD population. (neurology.org)
Occipital lobes1
- CNS toxoplasmosis produces multifocal lesions, with a predilection for the basal ganglia and the frontal, parietal, and occipital lobes. (aao.org)
Occur6
- Ganglion cysts can occur at any joint or tendon sheath, but they most often present in the dorsum of the wrist at the scapholunate joint, followed by the volar wrist. (medscape.com)
- A ganglion cyst (synovial cyst) is a fluid filled membrane that can occur around any joint in the body. (connecticutchildrens.org)
- Ganglion cysts are not limited to any specific location as they can occur near any joint in the body, commonly in the back of the knee (Baker's Cyst) and in the foot. (connecticutchildrens.org)
- The involuntary movement might occur due to the unequal distribution of the blood flow in the basal ganglia. (scirp.org)
- Although anyone can be affected by ganglion cysts, they occur three times as often in women as they do in men. (medscape.com)
- Which of the following types of ganglia occur in chains on either side of the vertebral column? (easynotecards.com)
Nerves4
- If the ganglion puts pressure on nearby nerves, you may have tingling in your fingers, hand, or forearm. (alberta.ca)
- Although many ganglions produce no other symptoms besides the appearance of a mass, if a cyst puts pressure on the nerves that pass across the joint, it can cause pain, tingling, and muscle weakness. (orthoinfo.org)
- Activity often causes the ganglion to increase in size, which may increase pressure on surrounding nerves, causing pain. (orthoinfo.org)
- A stellate ganglion block is an injection of local anesthetic (numbing medicine) to block the sympathetic nerves located on either side of the voice box in the neck. (umms.org)
Retina2
- This paper by Devid Damiani, Elena Novelli, Francesca Mazzoni and Enrica Strettoi documents continued negative plasticity in retina by examining ganglion cells in the rd1 mouse. (utah.edu)
- A 3-D human retina organoid system that mimics the physiological and morphological features of the in vivo biology, consists of the major retina cell types (rod and cone photoreceptors, horizontal, bipolar, amacrine, and ganglion cells and Muller glia) with appropriate lamination and synaptic organization, and represents their biological functions and interplay. (nih.gov)
Nervous2
- The ganglion impar also is located just anterior to the coccyx, so a potential risk of injury to the sympathetic nervous system exists during coccygectomy. (medscape.com)
- In humans, this process was found to be regulated by the closely related transporter, OATP1B1 that regulates cellular uptake of paclitaxel into dorsal root ganglia, the main site of drug accumulation within the nervous system. (cancer.gov)
Tumors3
- Sometimes, an MRI or ultrasound is needed to find an occult ganglion that is not visible, or to distinguish the cyst from other tumors. (orthoinfo.org)
- [ 1 ] Representing about 60% of these benign tumors is the ganglion cyst. (medscape.com)
- Ganglion cysts are the most common soft-tissue tumors of the hand and wrist. (medscape.com)
Volar2
- Transillumination of recurrent multilobulated left volar ganglion cyst. (medscape.com)
- Rocchi L, Canal A, Fanfani F, Catalano F. Articular ganglia of the volar aspect of the wrist: arthroscopic resection compared with open excision. (medscape.com)
Calcification3
- IMSEAR at SEARO: Basal ganglia calcification. (who.int)
- Basal ganglia calcification (BGC) is now being diagnosed with increasing frequency with widespread application of computed tomography (CT) in clinical practice and is no more considered a rarity. (who.int)
- This study highlights the fact that calcification of basal ganglia and other parts of the brain is often a nonspecific finding on CT scan and it may not be possible to establish a clinicopathological correlation. (who.int)
Cancerous2
- Ganglions aren't cancerous. (alberta.ca)
- This is typically safe because ganglions are not cancerous and may disappear on their own in time. (orthoinfo.org)
Brain6
- Any condition that can cause brain injury can damage the basal ganglia. (medlineplus.gov)
- Many brain disorders are associated with basal ganglia dysfunction. (medlineplus.gov)
- The main task of the basal ganglia-a group of subcortical nuclei, located at the base of the brain-is to optimize and execute our automatic behavior. (mit.edu)
- Explaining this leap into domains rarely explored in neuroscientific accounts, Bergman writes that the longer he studies the basal ganglia, the more he is convinced that they are truly the base of both brain and mind. (mit.edu)
- Group A streptococcus bacteria can react with a part of the brain called the basal ganglia to cause this disorder. (medlineplus.gov)
- Example: dystonia is known to origin in the basal ganglia, but it is also suspected or known that the cortex and maybe other areas of the brain have an impact in dystonia. (dystonia-europe.org)
Autonomic2
Surgically1
- Sometimes, doctors need to remove ganglia surgically. (msdmanuals.com)
Aspiration4
- Unfortunately, aspiration frequently fails to eliminate the ganglion because the root or connection to the joint or tendon sheath is not removed. (orthoinfo.org)
- Thus, in many cases, the ganglion cyst returns after an aspiration procedure. (orthoinfo.org)
- If ganglia are painful or keep growing, doctors can remove the fluid inside it with a needle (called aspiration). (msdmanuals.com)
- Multiple nonsurgical modalities have been used over the years for ganglion cyst, including simple aspiration. (medscape.com)
Scaphotrapezial joint1
- [ 5 ] A ganglion cyst can also arise from the radioscaphoid or scaphotrapezial joint volarly. (medscape.com)
Symptoms6
- A common cause of the symptoms of basal ganglia dysfunction is chronic use of medicines used to treat schizophrenia. (medlineplus.gov)
- Ganglions are usually small, painless bumps and do not cause other symptoms. (alberta.ca)
- But treatment may be needed if the ganglion causes pain or other symptoms, limits what you can do, affects your bones or ligaments, or gets infected. (alberta.ca)
- Ganglions are usually painless bumps that don't cause other symptoms. (peacehealth.org)
- A wrist brace or splint may relieve symptoms and cause the ganglion to decrease in size. (orthoinfo.org)
- What are the symptoms of ganglia? (msdmanuals.com)
Recurrence1
- This again can lead to recurrence of the ganglion cyst in about 50% of cases. (connecticutchildrens.org)
Wrist and hand1
- Ganglion of the wrist and hand. (alberta.ca)
Mucous3
- Unlike with the ganglia of the wrist, mucous cysts can cause the overlying skin to become thinned and may even lead to skin rupture. (medscape.com)
- A common type of ganglion called a mucous cyst ganglion occurs with arthritis of the hands. (alberta.ca)
- Ganglion cysts that develop at the end joint on the nail side of a finger - also known as mucous cysts - are typically associated with arthritis in the finger joint, and are more common in women between the ages of 40 and 70. (orthoinfo.org)
Pathogenesis2
- Soren A. Pathogenesis and treatment of ganglion. (medscape.com)
- Recent studies have suggested the implication of the basal ganglia in the pathogenesis of schizophrenia. (cun.es)
Including Parkinson's disease2
- He discusses the computational physiology of the healthy basal ganglia, describing four generations of computational models, and then traces the computational physiology of basal ganglia-related disorders and their treatments, including Parkinson's disease and its pharmacological and surgical therapies. (mit.edu)
- The basal ganglia are abnormal in a number of important neurologic conditions, including Parkinson's disease and Huntington's disease . (rxlist.com)
Arthroscopic1
- Arthroscopic resection in the management of dorsal wrist ganglions: results with a minimum 2-year follow-up period. (medscape.com)
Tendon1
- A ganglion can grow out of a joint capsule, which surrounds the joint , or a tendon sheath, which covers the tendon (the fibres connecting muscle to bone). (alberta.ca)
Arises1
- A ganglion arises out of a joint, like a balloon on a stalk. (orthoinfo.org)
Nonsurgical2
- The Efficacy of Nonsurgical and Surgical Interventions in the Treatment of Pediatric Wrist Ganglion Cysts. (medscape.com)
- Initial treatment of a ganglion cyst is nonsurgical. (orthoinfo.org)
Dysfunction1
- A person with basal ganglia dysfunction may have trouble starting, stopping, or sustaining movement. (medlineplus.gov)
Joint capsule2
- Ganglion cysts are caused when normal joint fluid leaks out of the joint capsule due to a capsular injury (sprain) or due to a weakened portion of the capsule from overuse. (connecticutchildrens.org)
- Dorsal ganglia most often affect the scapholunate joint, and the scaphoid interosseus ligament and extensor tendons must be considered because they are closely associated with the joint capsule. (medscape.com)
Lump3
- A ganglion cyst is a fluid-filled noncancerous lump that usually develops in the wrist or hand. (healthline.com)
- Ganglion cysts are the most common mass or lump in the hand. (orthoinfo.org)
- The only symptom of ganglia is the lump on your wrist or hand. (msdmanuals.com)
Treatment10
- Although physical therapy was the primary treatment in the study, baclofen, ganglion impar blocks, and coccygeus trigger point injections were also used. (medscape.com)
- Surgery is usually seen as a last resort for ganglion cyst treatment. (healthline.com)
- Before deciding to remove a ganglion cyst, your doctor will discuss other treatment options. (healthline.com)
- footnote 1 Children don't usually have ganglions, but if they do, the ganglion will very likely go away without any treatment. (alberta.ca)
- Ganglions usually don't need treatment, and they often go away on their own. (alberta.ca)
- With or without treatment, ganglions may come and go and may get bigger or smaller. (alberta.ca)
- Stellate ganglion block (SGB) has been the alternative treatment of Meniere's disease for years. (clinicaltrials.gov)
- Most ganglia go away on their own without treatment. (msdmanuals.com)
- [ 7 ] The patient can experience paresthesias and pain from a ganglion cyst, and in such cases, surgical treatment should be considered, to provide a favorable outcome with few complications. (medscape.com)
- Potential advances in sclerosing agents specific to the treatment of ganglion cysts may lead to a definitive medical treatment of ganglions, which would avoid surgery. (medscape.com)
Symptom1
- Age at onset and length of trinucleotide repeat correlated significantly with amount of volume change in caudate and total basal ganglia, even after controlling for length of interimage interval, duration of disease, and measures of symptom severity. (neurology.org)
Cervical4
- The stellate ganglion is part of the sympathetic network formed by the inferior cervical and first thoracic ganglia. (medscape.com)
- The cervical sympathetic chain is composed of the superior, middle, and inferior cervical ganglia. (medscape.com)
- In approximately 80% of the population, the inferior cervical ganglion fuses with the first thoracic ganglion, forming the cervicothoracic ganglion also known as the stellate ganglion. (medscape.com)
- Involvement of nicotinic and muscarinic receptors in synaptic transmission in cat superior cervical ganglions reinnervated by vagal primary afferent axons. (aspetjournals.org)
Occult2
- The occult dorsal carpal ganglion. (medscape.com)
- however, smaller ganglions can remain hidden under the skin (occult ganglions). (orthoinfo.org)
Inferior1
- The lung apex lies anterior and inferior to the ganglion. (medscape.com)