Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.
Compounds that contain a BENZENE ring fused to a furan ring.
Chlorinated hydrocarbons containing heteroatoms that are present as contaminants of herbicides. Dioxins are carcinogenic, teratogenic, and mutagenic. They have been banned from use by the FDA.
Synthetic organic reactions that use reactions between unsaturated molecules to form cyclical products.
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
A group of compounds that are derivatives of methoxybenzene and contain the general formula R-C7H7O.
Organic compounds containing a carbonyl group in the form -CHO.
Amidines substituted with a benzene group. Benzamidine and its derivatives are known as peptidase inhibitors.
Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.
Derivatives of benzene in which one or more hydrogen atoms on the benzene ring are replaced by bromine atoms.
Rhodium. A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh. (Dorland, 28th ed)
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
A group of DITERPENES cyclized into 2-rings with a side-chain.
A benign tumor of the intrahepatic bile ducts.
Hydrocarbons with at least one triple bond in the linear portion, of the general formula Cn-H2n-2.
A chemical by-product that results from burning or incinerating chlorinated industrial chemicals and other hydrocarbons. This compound is considered an environmental toxin, and may pose reproductive, as well as, other health risks for animals and humans.
A course of action or principle adopted or proposed by a government, party, business, or individual that concerns human interactions with nature and natural resources.
Contamination of the air, bodies of water, or land with substances that are harmful to human health and the environment.
The external elements and conditions which surround, influence, and affect the life and development of an organism or population.
An agency in the Executive Branch of the Federal Government. It was created as an independent regulatory agency responsible for the implementation of federal laws designed to protect the environment. Its mission is to protect human health and the ENVIRONMENT.
The protection, preservation, restoration, and rational use of all resources in the total environment.
The science of controlling or modifying those conditions, influences, or forces surrounding man which relate to promoting, establishing, and maintaining health.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
High temperature destruction of waste by burning with subsequent reduction to ashes or conversion to an inert mass.
The study, utilization, and manipulation of those microorganisms capable of economically producing desirable substances or changes in substances, and the control of undesirable microorganisms.
Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.
Hydrocarbon-rich byproducts from the non-fossilized BIOMASS that are combusted to generate energy as opposed to fossilized hydrocarbon deposits (FOSSIL FUELS).
The attitude of a significant portion of a population toward any given proposition, based upon a measurable amount of factual evidence, and involving some degree of reflection, analysis, and reasoning.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
The relationships of groups of organisms as reflected by their genetic makeup.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
A colorless liquid used as a solvent and an antiseptic. It is one of the ketone bodies produced during ketoacidosis.
Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.
Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)
Enzymes of the transferase class that catalyze the transfer of a pentose group from one compound to another.
A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes visceral leishmaniasis (LEISHMANIASIS, VISCERAL). The sandfly genera Phlebotomus and Lutzomyia are the vectors.
The presence of an infectious agent on instruments, prostheses, or other inanimate articles.
The presence of organisms, or any foreign material that makes a drug preparation impure.
Common name for a number of different species of fish in the family Cyprinidae. This includes, among others, the common carp, crucian carp, grass carp, and silver carp.
A family of enveloped, linear, double-stranded DNA viruses infecting a wide variety of animals. Subfamilies, based on biological characteristics, include: ALPHAHERPESVIRINAE; BETAHERPESVIRINAE; and GAMMAHERPESVIRINAE.
Diseases of freshwater, marine, hatchery or aquarium fish. This term includes diseases of both teleosts (true fish) and elasmobranchs (sharks, rays and skates).
An unassigned genus in the family HERPESVIRIDAE, comprising one species Ictalurid herpesvirus 1 (Channel Catfish Virus).
Virus diseases caused by the HERPESVIRIDAE.

Development of muscarinic analgesics derived from epibatidine: role of the M4 receptor subtype. (1/1563)

Epibatidine, a neurotoxin isolated from the skin of Epipedobates tricolor, is an efficacious antinociceptive agent with a potency 200 times that of morphine. The toxicity of epibatidine, because of its nonspecificity for both peripheral and central nicotinic receptors, precludes its development as an analgesic. During the synthesis of epibatidine analogs we developed potent antinociceptive agents, typified by CMI-936 and CMI-1145, whose antinociception, unlike that of epibatidine, is mediated via muscarinic receptors. Subsequently, we used specific muscarinic toxins and antagonists to delineate the muscarinic receptor subtype involved in the antinociception evoked by these agents. Thus, the antinociception produced by CMI-936 and CMI-1145 is inhibited substantially by 1) intrathecal injection of the specific muscarinic M4 toxin, muscarinic toxin-3; 2) intrathecally administered pertussis toxin, which inhibits the G proteins coupled to M2 and M4 receptors; and 3) s.c. injection of the M2/M4 muscarinic antagonist himbacine. These results demonstrate that the antinociception elicited by these epibatidine analogs is mediated via muscarinic M4 receptors located in the spinal cord. Compounds that specifically target the M4 receptor therefore may be of substantial value as alternative analgesics to the opiates.  (+info)

A comparison of an A1 adenosine receptor agonist (CVT-510) with diltiazem for slowing of AV nodal conduction in guinea-pig. (2/1563)

1. The purpose of this study was to compare the pharmacological properties (i.e. the AV nodal depressant, vasodilator, and inotropic effects) of two AV nodal blocking agents belonging to different drug classes; a novel A1 adenosine receptor (A1 receptor) agonist, N-(3(R)-tetrahydrofuranyl)-6-aminopurine riboside (CVT-510), and the prototypical calcium channel blocker diltiazem. 2. In the atrial-paced isolated heart, CVT-510 was approximately 5 fold more potent to prolong the stimulus-to-His bundle (S-H interval), a measure of slowing AV nodal conduction (EC50 = 41 nM) than to increase coronary conductance (EC50 = 200 nM). At concentrations of CVT-510 (40 nM) and diltiazem (1 microM) that caused equal prolongation of S-H interval (approximately 10 ms), diltiazem, but not CVT-510, significantly reduced left ventricular developed pressure (LVP) and markedly increased coronary conductance. CVT-510 shortened atrial (EC50 = 73 nM) but not the ventricular monophasic action potentials (MAP). 3. In atrial-paced anaesthetized guinea-pigs, intravenous infusions of CVT-510 and diltiazem caused nearly equal prolongations of P-R interval. However, diltiazem, but not CVT-510, significantly reduced mean arterial blood pressure. 4. Both CVT-510 and diltiazem prolonged S-H interval, i.e., slowed AV nodal conduction. However, the A1 receptor-selective agonist CVT-510 did so without causing the negative inotropic, vasodilator, and hypotensive effects associated with diltiazem. Because CVT-510 did not affect the ventricular action potential, it is unlikely that this agonist will have a proarrythmic action in ventricular myocardium.  (+info)

Relationships between environmental organochlorine contaminant residues, plasma corticosterone concentrations, and intermediary metabolic enzyme activities in Great Lakes herring gull embryos. (3/1563)

Experiments were conducted to survey and detect differences in plasma corticosterone concentrations and intermediary metabolic enzyme activities in herring gull (Larus argentatus) embryos environmentally exposed to organochlorine contaminants in ovo. Unincubated fertile herring gull eggs were collected from an Atlantic coast control site and various Great Lakes sites in 1997 and artificially incubated in the laboratory. Liver and/or kidney tissues from approximately half of the late-stage embryos were analyzed for the activities of various intermediary metabolic enzymes known to be regulated, at least in part, by corticosteroids. Basal plasma corticosterone concentrations were determined for the remaining embryos. Yolk sacs were collected from each embryo and a subset was analyzed for organochlorine contaminants. Regression analysis of individual yolk sac organochlorine residue concentrations, or 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQs), with individual basal plasma corticosterone concentrations indicated statistically significant inverse relationships for polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans (PCDDs/PCDFs), total polychlorinated biphenyls (PCBs), non-ortho PCBs, and TEQs. Similarly, inverse relationships were observed for the activities of two intermediary metabolic enzymes (phosphoenolpyruvate carboxykinase and malic enzyme) when regressed against PCDDs/PCDFs. Overall, these data suggest that current levels of organochlorine contamination may be affecting the hypothalamo-pituitary-adrenal axis and associated intermediary metabolic pathways in environmentally exposed herring gull embryos in the Great Lakes.  (+info)

Oxidative bioactivation of the lactol prodrug of a lactone cyclooxygenase-2 inhibitor. (4/1563)

The lactol derivative of a lactone cyclooxygenase-2 inhibitor (DFU) was evaluated in vivo and in vitro for its potential suitability as a prodrug. DFU-lactol was found to be 10 to 20 times more soluble than DFU in a variety of aqueous vehicles. After administration of DFU-lactol at 20 mg kg-1 p.o. in rats, a Cmax of 7.5 microM DFU was reached in the plasma. After oral administration, the ED50s of DFU-lactol in the carrageenan-induced paw edema and lipopolysaccharide-induced pyresis assays in rats are comparable with the ED50s observed when dosing with DFU. Incubations of DFU-lactol with rat and human hepatocytes demonstrated that the oxidation of DFU-lactol can be mediated by liver enzymes and that a competing pathway is direct glucuronidation of the DFU-lactol hydroxyl group. Assays with subcellular fractions from rat liver indicated that most of the oxidation of DFU-lactol occurs in the cytosolic fraction and requires NAD(P)+. Human liver cytosol can also support the oxidation of DFU-lactol to DFU when NAD(P)+ is added to the incubations. Fractionation of human liver cytosolic proteins showed that at least three enzymes are capable of efficiently effecting the oxidation of DFU-lactol to DFU. Incubations with commercially available dehydrogenases suggest that alcohol and hydroxysteroid dehydrogenases are involved in this oxidative process. These data together suggest that lactols may represent useful prodrugs for lactone-containing drugs.  (+info)

Evolution of plant defense mechanisms. Relationships of phenylcoumaran benzylic ether reductases to pinoresinol-lariciresinol and isoflavone reductases. (5/1563)

Pinoresinol-lariciresinol and isoflavone reductase classes are phylogenetically related, as is a third, the so-called "isoflavone reductase homologs." This study establishes the first known catalytic function for the latter, as being able to engender the NADPH-dependent reduction of phenylcoumaran benzylic ethers. Accordingly, all three reductase classes are involved in the biosynthesis of important and related phenylpropanoid-derived plant defense compounds. In this investigation, the phenylcoumaran benzylic ether reductase from the gymnosperm, Pinus taeda, was cloned, with the recombinant protein heterologously expressed in Escherichia coli. The purified enzyme reduces the benzylic ether functionalities of both dehydrodiconiferyl alcohol and dihydrodehydrodiconiferyl alcohol, with a higher affinity for the former, as measured by apparent Km and Vmax values and observed kinetic 3H-isotope effects. It abstracts the 4R-hydride of the required NADPH cofactor in a manner analogous to that of the pinoresinol-lariciresinol reductases and isoflavone reductases. A similar catalytic function was observed for the corresponding recombinant reductase whose gene was cloned from the angiosperm, Populus trichocarpa. Interestingly, both pinoresinol-lariciresinol reductases and isoflavone reductases catalyze enantiospecific conversions, whereas the phenylcoumaran benzylic ether reductase only shows regiospecific discrimination. A possible evolutionary relationship among the three reductase classes is proposed, based on the supposition that phenylcoumaran benzylic ether reductases represent the progenitors of pinoresinol-lariciresinol and isoflavone reductases.  (+info)

Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein. (6/1563)

Acylated homoserine lactone (AHL)-mediated gene expression controls phenotypes involved in colonization, often specifically of higher organisms, in both marine and terrestrial environments. The marine red alga Delisea pulchra produces halogenated furanones which resemble AHLs structurally and show inhibitory activity at ecologically realistic concentrations in AHL bioassays. Evidence is presented that halogenated furanones displace tritiated OHHL [N-3-(oxohexanoyl)-L-homoserine lactone] from Escherichia coli cells overproducing LuxR with potencies corresponding to their respective inhibitory activities in an AHL-regulated bioluminescence assay, indicating that this is the mechanism by which furanones inhibit AHL-dependent phenotypes. Alternative mechanisms for this phenomenon are also addressed. General metabolic disruption was assessed with two-dimensional PAGE, revealing limited non-AHL-related effects. A direct chemical interaction between the algal compounds and AHLs, as monitored by 1H NMR spectroscopy, was shown not to occur in vitro. These results support the contention that furanones, at the concentrations produced by the alga, can control bacterial colonization of surfaces by specifically interfering with AHL-mediated gene expression at the level of the LuxR protein.  (+info)

NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone. (7/1563)

The proton-translocating NADH-quinone oxidoreductase (EC 1.6.99.3) is the largest and least understood enzyme complex of the respiratory chain. The mammalian mitochondrial enzyme (also called complex I) contains more than 40 subunits, whereas its structurally simpler bacterial counterpart (NDH-1) in Paracoccus denitrificans and Thermus thermophilus HB-8 consists of 14 subunits. A major unsolved question is the location and mechanism of the terminal electron transfer step from iron-sulfur cluster N2 to quinone. Potent inhibitors acting at this key region are candidate photoaffinity probes to dissect NADH-quinone oxidoreductases. Complex I and NDH-1 are very sensitive to inhibition by a variety of structurally diverse toxicants, including rotenone, piericidin A, bullatacin, and pyridaben. We designed (trifluoromethyl)diazirinyl[3H]pyridaben ([3H]TDP) as our photoaffinity ligand because it combines outstanding inhibitor potency, a suitable photoreactive group, and tritium at high specific activity. Photoaffinity labeling of mitochondrial electron transport particles was specific and saturable. Isolation, protein sequencing, and immunoprecipitation identified the high-affinity specifically labeled 23-kDa subunit as PSST of complex I. Immunoprecipitation of labeled membranes of P. denitrificans and T. thermophilus established photoaffinity labeling of the equivalent bacterial NQO6. Competitive binding and enzyme inhibition studies showed that photoaffinity labeling of the specific high-affinity binding site of PSST is exceptionally sensitive to each of the high-potency inhibitors mentioned above. These findings establish that the homologous PSST of mitochondria and NQO6 of bacteria have a conserved inhibitor-binding site and that this subunit plays a key role in electron transfer by functionally coupling iron-sulfur cluster N2 to quinone.  (+info)

Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: mechanism of action of the lung-toxic furan, 4-ipomeanol. (8/1563)

Many xenobiotics produce hepatic injury due to their metabolism in the liver to highly reactive electrophile intermediates which form covalent conjugates with nucleophilic cellular constituents. This presentation describes studies indicating that the production of chemically reactive metabolites by pulmonary metabolism of xenobiotics can also play a fundamental role in the pathogenesis of chemically induced lung disease.  (+info)

Buying a frame allows you to customize your build, which is a key advantage for buying a frame instead of a full bike.. You could have your own reasons for trying out the Furan Frame. We are here to help you evaluate whether its the best choice for you.. Hard knuckle mountain riding is Furans forte. Hand welded from 6061 Aluminum, Psynydes specially designed Hydroformed downtube, toptube and stays add rigidity without the bulk. Furans tapered head tube is evolved for todays new suspension forks out there. With our forged droputs and disc brake mounts the rear end of this hardtail is sorted for impact. Our elite geometry pumped into the Furans long toptube and slack styling will change the way you ride a trail hardtail.. Designed for the new 27.5 wheels, Furan is ready to roll over any terrain with ease. Created for trail forks between 100mm-130mm of travel, heres a hardtail thatll allow you to get wild on dirt!. Not just limited to the mountains and rocky world, the Furan can fireup the ...
2-Oxo-2,3-dihydrofuran-5-acetate; 3-Oxoadipate enol-lactone; 4,5-Dihydro-5-oxofuran-2-acetate; 5-Oxo-4,5-dihydrofuran-2-acetate; C03586 ...
Word Scramble - English word FURANS: words that start with furans, words that end with furans, anagrams of furans, how to spell furans!, Words with Friends, Scrabble
[(2S,5R)-5-(6-Aminopurin-9-yl)-2,5-dihydrofuran-2-yl]methanol | C10H11N5O2 | CID 268420 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
0033]Starting materials of formula (III) of the present invention are available commercially or from known methods in the art as disclosed in the following list: [0034]2,5-dimethyl-3(2H)-furanone, from Ryan Scientific Product List. [0035]4-(1,1-dimethylethyl)-2,5-dimethyl-3(2H)-furanone, from JP10036259. [0036](S)-2,5-dimethyl-3(2H)-furanone and (R)-2,5-dimethyl-(2H)-furanone, from Eghbaldar et al., Parfums, Cosmetiques, Aromes (1992), 104, 71-8. [0037](R)-5-hexyl-2-methyl-3(2H)-furanone and (S)-5-hexyl-2-methyl-3(2H)-furanone, from Mosandl et al. Journal of High Resolution Chromatography (1990), 13(9), 660-2. [0038]2-methyl-4-(2-methylpropyl)-3(2H)-furanone and 2-methyl-4-pentyl-3(2H)-furanone, from Baraldi et al. Tetrahedron (1987), 43(1), 235-42. [0039]2-methyl-5-(2-methylpropyl)-3(2H)-furanone, 2-methyl-5-phenyl-3(2H)-furanone, and 2-methyl-5-pentyl-3(2H)-furanone, from Baraldi et al. Tetrahedron Letters (1984), 25(38), 4313-16. [0040]5-hexyl-2-methyl-3(2H)-furanone, from Winkler et al. ...
The report generally describes (methylsulphonyl)benzene, examines its uses, production methods, patents. (methylsulphonyl)benzene market situation is
Toxic dioxins and furans can accumulate through industrial processes. SGS dioxin and furan analysis can accurately measure trace quantities to improve your site safety. Find out more.
While environmental controversy surrounding use of this fuel is wide and varied, the greatest supported evidence of toxicity comes from the presence of dioxins and furans in the flue gases. Zinc has also been found to dissolve into storm water, from shredded rubber, at acutely toxic levels for aquatic life and plants.[7]. A study of dioxin and furan content[8] of stack gasses at a variety of cement mills, paper mills, boilers, and power plants conducted in the 1990s shows a wide and inconsistent variation in dioxin and furan output when fueled partially by TDF as compared to the same facilities powered by only coal. Some facilities added as little as 4% TDF and experienced as much as a 4,140% increase in dioxin and furan emsissions. Other facilities added as much as 30% TDF and experienced dioxin and furan emissions increases of only as much as 58%. Still other facilities used as much as 8% TDF and experienced a decrease of as much as 83% of dioxin and furan emissions. One facility conducted ...
110-00-9 Furan (furane) testing. Laboratory testing for CAS number 110-00-9. Divinylene oxide;Furfuran;Oxacyclopentadiene;Oxole;Tetrole;Furane;Furfurane;NCI-C56202;Rcra waste number U124;UN 2389;QO Furan. This chemical is colourless liquid
QAYBTII SADEXAAD EE DOODII MAXAAN KU MUTAYSTAY HEYBSOOCA DOOD FURAN QAYBTII SADEXAAD EE DOODII MAXAAN KU MUTAYSTAY HEYBSOOCA DOOD FURAN marka ugu horeysa waxan salaan xushmad & qadariin ku dheehantahey ku salamaya ,dhamaan shaqaalaha websetka ,gaar ahaan mamulka shabakada , sidookale waxaan salan xushmad & qadariin ku dheehantahey waxaan ku salamaya dhamaan akhristaha sharafta badan…
RHYTHM CHEMICALS PVT. LTD., We are famous Manufacturer,Supplier,Wholesaler and Exporter of Tetrahydrofuran based in Surat, Gujarat, India.
[108 Pages Report] Check for Discount on United States Tetrahydrofuran Market Report 2021 report by QYResearch Group. Notes: Sales, means the sales volume of Tetrahydrofuran Revenue, means...
ID Reingold, HA Trujillo, BE Kahr. A new preparation of alpha-cycloheptatrienyl ketones J. Org. Chem. 1986, 51, 1627-1629. B Kahr, D Van Engen, K Mislow. The length of the ethane bond in hexaphenylethane and its derivatives J. Amer. Chem. Soc. 1986, 108, 8305-8307. B Kahr, SA Biali, W Schaefer, AB Buda, K Mislow. Molecular structure of hexakis(dichloromethyl)benzene J. Org. Chem. 1987, 52, 3713-3717. SA Biali, B Kahr, Y Okamoto, R Aburatani, K Mislow Structure, resolution and racemization decakis(dichloromethyl)biphenyl J. Am. Chem. Soc. 1988, 110, 1917-1922. RA Pascal, Jr, D Van Engen, B Kahr, WD McMillan Twisted polycyclic aromatic hydrocarbons Structural studies of protic and deuteriated 1,2,3,4-tetraphenyltriphenylenes J. Org. Chem. 1988, 53, 1687-1689. J. Chance, B Kahr, A B Buda, J. P Toscano, K Mislow Stereochemistry of hexakis(dimethylamino)benzene and its dication J. Org. Chem. 1988, 53, 3226-3232. N Yannoni, B Kahr, K Mislow Determination of the central bond length in hexaarylethanes ...
ELIMINATE all ignition sources and groumd all equipment used when handling the product. Do not touch spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. A vapor suppressing foam may be used to reduce vapors. FOR CHLOROSILANES, use AFFF alcohol-resistant medium expansion foam to reduce vapors. DO NOT GET WATER on spilled substance or inside containers. Cover with DRY earth, DRY sand, or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean non-sparking tools to collect material and place it into loosley covered plastic containers for later disposal ...
Page contains details about Concanavalin A/bovine serum albumin-incorporated LA-conjugated Tetronic® 1107 micelles aggregates . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
Find quality suppliers and manufacturers of 497-23-4(2(5H)-Furanone) for price inquiry. where to buy 497-23-4(2(5H)-Furanone).Also offer free database of 497-23-4(2(5H)-Furanone) including MSDS sheet(poisoning, toxicity, hazards and safety),chemical properties,Formula, density and structure, solution etc.
5-Fluoro-7-(methylsulphonyl)-1H-indole-2-carboxylic acid/ACM849035876 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
Learn how APGC coupled to a Xevo TQ-S tandem quadrupole instrument can better characterize dioxin and furan generation (polybromo- and mixed halogenated) that firefighters and first responders are exposed to.
Adhere to stringent environmental regulation with our comprehensive range of reference materials for dioxin & furan testing. 500+ products available online.
Creative-Proteomics offer cas NA BROMINATED DIOXIN/FURAN LABELED COMPOUNDS (13C12, 99%). We are specialized in manufacturing Stabel Isotope Labeled Analytical Standard products.
A highly efficient Au-catalyzed cyclization of (Z)-enynols that proceeds under mild reaction conditions has been developed. This methodology provides rapid access to Substituted furans and stereodefined (Z)-5-ylidene-2,5-dihydrofurans in a regioselective manner frorn suitably Substituted (Z)-2-en-4-yn-1-ols. (C) 2008 Elsevier Ltd. All rights reserved ...
Creative-Proteomics offer cas NA MODIFIED JIS LOW CONCENTRATION DIOXIN & FURAN CALIBRATION SOLN CS2L (UNLABELED/13C12, 99%). We are specialized in manufacturing Stabel Isotope Labeled Analytical Standard products.
ChemInform Abstract: Synthesis of New 2- or 3-Deoxy Carbapyranoses from Furan.|span||/span| | Odon Arjona; Gema Lorenzo; Rocio Medel; Joaquin Plumet | download | BookSC. Download books for free. Find books
FURAN | C4H4O | CID 8029 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
2,3,5-Trifluorotetrahydro-4-(pentafluoroethyl)-2,3,4,5-tetrakis(trifluoromethyl)furan/ACM69661309 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
125372-43-2 - VLTVCYQMCFCYBJ-UHFFFAOYSA-N - Naphtho(2,1-b)furan, 7-isothiocyanato-2-nitro- - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Get the latest furan contamination news on Environmental XPRT, the worlds largest environmental industry marketplace and information resource.
To elucidate possible mechanism(s) of carcinogenic action of tetrahydrofuran (THF) that had been demonstrated in previous inhalation studies, groups of male F344 rats and female B6C3F1 mice were exposed to dynamic atmospheric concentrations of 0, 600, 1800, or 5400 mg/m3 for 6 h per day, either for 5 consecutive days or for a period of 4 weeks (5 days per week). The reversibility of treatment-related changes was investigated in rats and mice exposed for 5 days and sacrificed 21 days after the last exposure. Female B6C3F1 mice exposed to 5400 mg/m3 showed significantly increased cytochrome P450 content, increased ethoxyresorufin-O-deethylase and pentoxyresorufin-O-depentylase activities, increased cell proliferation (5-bromo-2-deoxyuridine-method) and an increased mitotic index in liver zones 2 (midzonal region) and 3 (central vein region). The changes were found to be reversible after a 3-week treatment-free period (cell proliferation examined, only). Male F344 rats showed dose-related ...
2-(furan-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 248924-59-6 route of synthesis, 2-(furan-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical synthesis methods, 2-(furan-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane synthetic routes ect.
1-[4-(furan-2-yl)phenyl]ethanone 35216-08-1 NMR spectrum, 1-[4-(furan-2-yl)phenyl]ethanone H-NMR spectral analysis, 1-[4-(furan-2-yl)phenyl]ethanone C-NMR spectral analysis ect.
Italy and #OperationGreenRights are still working on the data, about the chemical agents, contained in the dumps of Ilvas and Riva Groups database (www.ilvataranto.com & www.rivagroup.com). The chemical agents tables, sometimes, are not easy to read, sometimes is not possible to understand which is the real grade of production, of these materials, but is sure that some values are not crossable. Another certain is that these limits are applied by the law. The factories, which produce chemical agents over the limits set by the law, make this work dangerous for all the people who works in these places and for who lives in these cities. The limits are decided by the law, so are not changeable by the owners of these factories. One of the most dangerous chemical agent produced is furan (C4H4O). The furan is an organic persistent enviromental pollutant which naturally becames benzofuran polychlorinated, whom is associated to dioxins. Also normally, the furan is highly volatile close to room ...
By now you should have spent a good amount of time using the main dial on your…camera to configure all sorts of options.…You can reverse the direction that the dial works in by going here into the…Custom Setting menu, into Controls, and scrolling down to Reverse dial rotation.…Now, the reason were talking about this particular custom setting is that if you…watched the previous movies and chose to reverse your indicators--this is the…one where plus and minus are swapped in the Exposure Compensation display--…if youve done that then youre probably going to want to reverse the dial…location for your camera, simply to feel like it makes sense.… So if I just turn this on, now things that used to happen when I scrolled to the…left will happen when I scroll to the right.…So if I reversed my indicators, reversing the dial rotation is going to make the…dial feel like its fitting more with what Im seeing in my Exposure…Compensation indicator.… ...
Golka, Leonie; 2019: Kinetische Untersuchungen zur Pyrolyse oxygenierter Kohlenwasserstoffe: Stoßwellenexperimente und kinetische Modellierungen. Jöckle, Philipp; 2019: Visible light-triggered precursor molecules: relating reactivity and ultrafast dynamics. Schweigert, Caroline; 2018: Untersuchungen Lokaler Umgebungsvariation auf das Relaxationsverhalten Photoangeregter Zustände von Molekülen in Lösung Mittels Femtosekunden-Breitband-Absorptionsspektroskopie. Janzer, Corina; 2017: NO2-Bildung unter Motorischen Bedingungen: Kinetische Modellierungen und Stoßwellenexperimente. Weber, Isabelle; 2017: Kinetic Studies with Shock Tubes: Instrumental Developments and the Thermal Decompostiion of Furan Derivatives. Eble, Julia; 2017: Zündung oxygenierter Kohlenwasserstoffe: Mechanismus und Elementarschritte. Bänsch, Cornelie; 2017: Reactions of Hydroxyl Radicals with Oxygenated Hydrocarbons in the Gas Phase: A Laser Photolysis/Laser-Induced Fluorescence Study. Kiecherer, Johannes; 2016: ...
About ranitidinea histamine h2-receptor antagonist, furan derivative, anti-secretory g.i agent,anti ulcer.mechanism of action of ranitidineranitidine
About ranitidinea histamine h2-receptor antagonist, furan derivative, anti-secretory g.i agent,anti ulcer.mechanism of action of ranitidineranitidine
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Metabolic products of microorganisms. 197. Investigations on metabolites of microorganisms. 23. Tetronic acid derivatives from Aspergillus panamensis. Production, isolation, characterization and biological activity. Anke, H.; Schwab, H.; Achenbach, H. Inst. Biol. II, Univ. Tuebingen, Tuebingen, Fed. Rep. Ger. Journal of Antibiotics (1980), 33(9), 931-9 ...
A new Streptomyces strain was isolated from the soil of volcanic Cheju Island, which produces a novel immunosuppressive molecule. The active compound was purified through various chemical methods and identified as TMC, which was originally found as an antifungal antibiotic. A comparable level of inhibition of T lymphocyte proliferation induced by mouse MLR or the mitogen Con A was observed with a 100-fold lower concentration of TMC than CsA. Although the induction of IL-2 gene expression was inhibited by both TMC and CsA, TMC showed the inhibition of the surface expression of CD69 or IL-2Rα chain. These findings suggested that TMC has the capacity to inhibit the intracellular signaling pathway leading to T cell activation and proliferation, and its mechanism of action is different from that of CsA.. Among the intracellular signaling events proximal to the TcR complex, TMC inhibited T lymphocyte activation by blocking the tyrosine phosphorylation induction of the T cell-specific signal mediator ...
51756-68-4 - LPUKOCDKXPMREF-QKIOLIMFSA-N - 2-(2-Hydroxy-7-(N-(5-hydroxy-2,4-dimethyl-6,9-dioxonaphtho(2,1-b)furan-7-yl)carbamoyl)-1,3-dimethylocta-4,6-dienyl)-6-(2,2-dimethoxyethyl)-3-methylperhydropyran-4-yl acetate - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Product Name: 4-bromo-6-tert-butyldibenzofuranFormula: C16H15OBrWeight: 303.1937SMILES: BrC1C2=C(C=CC=1)C3C(O2)=C(C=CC=3)C(C)(C)CCAS NO: 104010-37-9 Product:
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Product Name: 8-Chloro-benzonaphthofuranFormula: C16H9OClWeight: 252.69506SMILES: ClC1C2=C(C=CC=1)C3=C4C(C=CC=C4)=CC=C3O2CAS NO: 1146-98-1 Product: Bromindione
Landolt-Börnstein - Group II Molecules and Radicals | Volume 29D2 | Book DOI: 10.1007/978-3-642-10400-8 | SpringerMaterials 2011
IPEN is a unique global network of people and public interest organizations, which respects and enjoys a wide diversity of cultures, skills and knowledge. Together we share a common commitment to achieve a toxic-free future where chemical production, use and disposal does not harm people and the environment.. ...
67 degree head angle keeps the bike well planted on descents and adds to the Long Slack Low design language.. 120mm fork (longest travel in its segment). The geometry of the bicycle is designed considering average height of Indian Population. Customizable Cockpit: ...
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The formation of furam and certain volatiles related to furan formation mechanisms was studied using gas chromatography-mass spectrometry combined with solid-phase micro extraction after adding dicarbonyl trapping agents [epicatechin (EC), epigallocatechin gallate (EGCG), and catechin] water-soluble antioxidants (Trolox, caffeic acid, ferulic acid, and chlorogenic acid), fat-soluble antioxidants (e-tocopherol, BHT, and beta-carotene), and reducing agents (glutathione and sodium sulfite) to canned-coffee model systems (CMS). The level of furan formation decreased significantly following the addition of EC (by 65.3%), EGCG (by 60.0%), and catechin (by 44.7%). In addition, the formation of Maillard reaction products, including furan derivatives (furfural and 5-methylfurfural), Strecker aldehyde (2-methylbutanal), pyrazines (2,6-dimethylpyrazine), and lipid oxidation products (including hexanal and 2-pentylfuran) was suppressed when any of the dicarbonyl trapping agents was added. Among the ...
Find quality suppliers and manufacturers of 88-14-2(2-Furoic acid) for price inquiry. where to buy 88-14-2(2-Furoic acid).Also offer free database of 88-14-2(2-Furoic acid) including MSDS sheet(poisoning, toxicity, hazards and safety),chemical properties,Formula, density and structure, solution etc.
Eribulin mesylate: View Uses, Side Effects and Medicines, cost care | Eribulin mesylate uses, side-effects, care price, drug interactions, expert advice and user FAQs only on MHP.ooo.
VALLEY COTTAGE, N.Y. - Furfuryl alcohol (C4H3OCH2OH), also known as 2-furylmethanol or 2-furancarbinol, is an organic compound containing a furan substituted with a hydroxymethyl group. Furfuryl alcohol is made from furfural by means of catalysis with hydrogen. It is colourless or pale yellow in appearance and find...
Various furans are considered as valuable platform chemicals as they can be derived from plant biomass. Yet, for their exploitation, follow-up chemistry is required. Here we demonstrate that Baeyer-Villiger monooxygenases (BVMOs) can be used as biocatalysts for the selective oxidation of several furans, including 5-(hydroxymethyl) furfural (HMF) and furfural. A total of 15 different BVMOs were tested for their activity on furfural, which revealed that most of the biocatalysts were active on this aromatic aldehyde. Phenylacetone monooxygenase (PAMO) and a mutant thereof (PAMOM446G) were selected for studying their biocatalytic potential in converting furfural and some other furans. While BVMOs are usually known to form an ester or lactone as a normal product by inserting an oxygen atom adjacent to the carbonyl carbon of the substrate, our results reveal that both biocatalysts produce furanoid acids as the main product from the corresponding aldehydes. Altogether, our study shows that BVMOs can be
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TY - CHAP. T1 - Marine sponge derived eribulin in preclinical and clinical studies for cancer. AU - Swami, Umang. AU - Shah, Umang. AU - Goel, Sanjay. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Eribulin mesylate is a completely synthetic, structurally simplified, macrocyclic ketone analogue of Halichondrin B. Halichondrin B is complex, natural, macrocyclic polyether derived from marine sponges. Eribulin has been approved by United States Food and Drug Administration in 2010 as a third line therapy for metastatic breast cancer patients, who have previously been treated with an anthracycline and a taxane. It has a microtubule dynamics inhibitory action. Preclinical studies have demonstrated a broad spectrum of anti-tumor activity in various cancer cell lines and synergistic action with multiple anticancer agents. It has also undergone clinical trials in non-small cell lung cancer, pancreatic, prostate, bladder, head and neck cancers, sarcomas and ovarian and other gynecological tumors. Various combination ...
This randomized phase II trial studies the side effects of atezolizumab with or without eribulin mesylate and how well they work in treating patients with
2-Furoyl chloride is an acyl chloride of furan. It takes the form of a corrosive liquid, which is more irritating to the eyes than benzoyl chloride. 2-Furoyl chloride is a useful pharmaceutical intermediate and is used in the synthesis of mometasone furoate, an antiinflammatory prodrug used in the treatment of skin disorders, hay fever and asthma. 2-Furoyl chloride was prepared in 1924 by Gelissen by refluxing 2-furoic acid in excess thionyl chloride on a water bath. 2-Furoyl chloride has no major applications but it has been used as a chemical intermediate in the synthesis of various pharmaceuticals; examples include mometasone furoate, fluticasone furoate, diloxanide furoate, Ceftiofur (Excenel), and mirfentanil. Another use is in the patented synthesis of Diclofurime (Ex 15). Furfurylamine - corresponding amine Furfuryl alcohol - corresponding alcohol Furan-2-ylmethanethiol - corresponding thiol 2-Furoic acid - corresponding carboxylic acid H. Gelissen; van Roon, J. D. (1924). Furfuroyl ...
Eribulin mesylate (eribulin), an analogue of the marine natural product halichondrin B, is a microtubule-depolymerizing drug that has utility in the treatment of patients with breast cancer. Clinical trial results have demonstrated that eribulin treatment provides a survival advantage to patients with metastatic or locally advanced breast cancer previously treated with an anthracycline and a taxane. Furthermore, a pooled analysis of two pivotal phase III trials has demonstrated that eribulin also improves overall survival in several patient subgroups, including in women with HER2-negative disease and triple-negative breast cancer. This review covers the preclinical research that led to the clinical testing and approval of eribulin, as well as subsequent research that was prompted by distinct and unexpected effects of eribulin in the clinic. Initial studies with halichondrin B demonstrated unique effects on tubulin binding that resulted in distinct microtubule-dependent events and antitumor ...
Lariciresinol is a phytochemical in the class of Lignans (phytoestrogens), found abundantly in sesame seed, brassica vegetables, etc. Health Benefits 1. Mammary tumor growth and reduces blood vessel density In the investigation of the effects and possible mechanisms of action of lariciresinol on hormone responsive mammary cancer in vivo in dimethylbenz[a]anthracene induced mammary cancer in …. ...
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Abstract A series of 3-[5-nitro(furan/thiophene)-2-yl]-1-aryl-3-(5-aryl-1,3,4-oxadiazol-2-ylthio)prop-2-en-1-one derivatives was synthesized and studied with the aim of developing dual inhibitors of...
The present invention concerns the synthesis of 5-methyl-2-furoic acid, including ester, amide, and thioester derivatives of such from 5-(chloromethyl)-2-furaldehyde (CMF). The molecules so prepared are useful as intermediates for pharmaceutical, food, and fragrance molecules; as well as fuel or fuel additives.
As the measurements of PCDD/PCDFs are complex, there is no reliable estimation of emissions in most of low- and middle-income countries. In order to help countries identify sources of emissions and to estimate release of PCDD/PCDFs, the United Nations Environment Program (UNEP) has established a Toolkit for Identification and Quantification of Releases of Dioxins, Furans and Other Unintentional Persistent Organic Pollutants (POPs) [21, 22]. The main objective of the Toolkit is to estimate the PCDD/PCDFs emissions from existing sources to the air, water, land, residue, and other products [22]. Therefore, emissions of PCDD/PCDFs were estimated by the methods proposed by the UNEP Toolkit, which consists of five-steps [21-23]. They are 1) the use of screening matrix to identify the major source categories of PCDD/PCDFs, 2) controlling subcategories to determine present activities and sources in the country, 3) collection of detailed information on the processes and classifying processes into similar ...
Palladium is probably the most useful metal in organic syntheses. It has shown great utility in various reactions such as C-C, C-N, C-O bond formation under mild conditions. The presence of abundant amount of palladium-chemistry related literature in the form of books, reviews emphasizes the growing importance of these reagents. Nowadays organopalladium chemistry is being used in various fields such as new methodology development, natural product synthesis, synthesis of polymers. Regio- and stereoselectivity is another facet of Pd catalyzed methodologies which has been extensively utilized in the last decade to obtain enantiopure compounds. The main emphasis of this work is to utilize Pd catalyzed allylic alkylation to synthesize new heterocycles including furans, isoxazolines and new cyclopentane amino-acid analogs in an enantioselective manner. The stereochemical outcome of these reactions is influenced by desymmetrization catalyzed by hydrolytic enzymes namely lipases. Chapter 1 reviews the recent
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First principles calculations including relativistic effects are carried out for dipole moments, polarizabilities, first- and second-order hyperpolarizabilities for the series of furan homologues XC4H 4, X = O, S, Se, Te, at three different levels of theory, time-dependent Dirac-Hartree-Fock (DHF), time-dependent Hartree-Fock with a Douglas-Kroll transformed one-component Hamiltonian, and time-dependent Hartree-Fock using effective-core potentials. By comparison with the corresponding non-relativistic results, the influence of relativistic effects on the properties as well as the accuracy of previously reported calculations on these molecules using effective-core potentials for selenium and tellurium can be addressed. The obtained results indicate that relativistic effects can be described with comparable accuracy at all three employed levels, and that non-scalar effects, which are explicitly treated only at the time-dependent DHF level, are of minor importance. Frequency dispersion and ...
Gitlitz BJ, Tsao-Wei DD, Groshen S, Davies A, Koczywas M, Belani CP, Argiris A, Ramalingam S, Vokes EE, Edelman M, Hoffman P, Ballas MS, Liu SV, Gandara DR. A phase II study of halichondrin B analog eribulin mesylate (E7389) in patients with advanced non-small cell lung cancer previously treated with a taxane: a California cancer consortium trial. J Thorac Oncol. 2012 Mar; 7(3):574-8 ...
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This invention provides a process for producing 4-hydroxybutanal in a yield of at least 87 percent by hydroformylation of allyl alcohol in a solvent at a temperature of about 20° C-120° C and a pressure of about 15-150 psi in the presence of a rhodium metal-phosphine complex hydroformylation catalyst. Also provided are additional processing procedures for recovering the 4-hydroxybutanal product and converting it into 1,4-butanediol and tetrahydrofuran.
Learn more about Tetrahydrofuran : propylene glycol. We enable science by offering product choice, services, process excellence and our people make it happen.
The purpose of this study is to verify that combination therapy with trastuzumab + pertuzumab + eribulin brings similar PFS and better QOL compared to
Described is a method of processing biomass to separate it into a liquid fraction enriched in solubilized C5-sugar-containing oligomers and C-5 sugar monomers and a solid fraction enriched in substantially insoluble cellulose and C6-sugar-containing oligomers. The method includes the steps of reacting biomass with a solvent system comprising water, at least one lactone, or at least one furan, or at least one cyclic ether, and at least one acid, for a time and at a temperature to yield the liquid and solid fractions. The liquid and solid fractions may then be separated. Gamma-valeroloactone is a preferred lactone for use in the solvent system. Tetrahydrofuran is a preferred furan species for use in the solvent system.
0130] The number average molecular weight of the polyamide acid is a value obtained by measuring a tetrahydrofuran (THF)-dissolved portion with gel permeation chromatography (GPC). Specifically, the measurement is carried out as follows: an apparatus HLC-8220 (available from TOSOH CORPORATION) and column TSK guardcolumn+TSK gel Super HZM-M3 triple series (available from TOSOH CORPORATION) are used; tetrahydrofuran (THF) is allowed to flow as a carrier medium at a flow rate of 0.2 ml/min while maintaining the column temperature at 40° C.; a sample to be measured is dissolved in tetrahydrofuran in a concentration of 1 mg/ml under dissolving conditions where ultrasonic treatment is carried out for 5 minutes with an ultrasonic disperser at room temperature; subsequently, a sample solution is prepared by treatment with a membrane filter having a pore size of 0.2 μm; 10 μl of this sample solution is injected into the apparatus together with the aforementioned carrier medium; detection is ...
Abstract: Singapore is reputed for its delicious seafood such as chili crab. One of the major components in the leftover crab shells is chitin, which is the world second most abundant renewable organic carbon resources bearing 7 wt% fixed nitrogen. This presentation will highlight recent advances within the group on the valorization chitin into value added chemicals and materials. The essence of these transformations is to harness the valuable functional groups originally presented in chitin, to produce furan derivatives, polyols, amino sugars and so on, via advanced catalysis.. At the end of the presentation, various other projects undergoing in the group will also be introduced.. About the speaker: Ning Yan is currently an Assistant Professor in the Department of Chemical & Biomolecular Engineering at the National University of Singapore. He was recently awarded the inauguration UNESCO Green Chemistry for Life Award. Before coming to NUS he was a Marie-Curie Research Fellow in Paul Dysons lab ...
Learn more about FDA-approved HALAVEN, an injectable chemotherapy treatment for metastatic breast cancer. Please see the full Indication and Important Safety Information for HALAVEN.
Learn more about HALAVEN, an injectable medicine used to treat certain patients with metastatic breast cancer (mBC). Please see the full Indication and Important Safety Information for HALAVEN.
A three-necked round bottom flask equipped with a stir bar, digital thermometer and argon inlet / outlet is charged with dry tetrahydrofuran (7.5 mL) and cooled to −78 ° C. Sodium borohydride (172.5 mg, 4.56 mmol) was added under a stream of argon, then diethyl-methoxyborane (0.694 g, 50% solution in tetrahydrofuran, 3.47 mmol) at −78 ° C. Added. The mixture is stirred for 5 minutes at this temperature. Then crude (E)-(R) -7- [2-cyclopropyl-4- (4-fluorophenyl) quinoline-3-dissolved in dry tetrahydrofuran (1.8 mL) and dry methanol (2.2 mL). Yl] -3-hydroxy-5-oxo-6-heptenoic acid ((S) -1-phenyl-ethyl) amide (1.84 g, 3.52 mmol) was slowly added in about 30 minutes at -78 ° C. Add dropwise and continue stirring at this temperature for 1 hour. For workup, the reaction mixture is poured into a solution of sodium bicarbonate (0.383 g) in water (12 mL) and isopropyl acetate (30 mL) is added. The biphasic solution is stirred at room temperature for 30 minutes until gas evolution ceases. Separate ...
An SAE is any untoward medical occurrence that at any dose: results in death; is life threatening (ie, the participant was at immediate risk of death from the adverse event as it occurred; this does not include an event that, had it occurred in a more severe form or was allowed to continue, might have caused death); requires inpatient hospitalization or prolongation of existing hospitalization; results in persistent or significant disability/incapacity; is a congenital anomaly/birth defect (in the child of a participant who was exposed to the study drug). A treatment-emergent adverse event (TEAE) is defined as an AE that emerges during treatment, having been absent at pretreatment (Baseline) or (1) reemerges during treatment, having been present at pretreatment (Baseline) but stopped before treatment, or (2) worsens in severity during treatment relative to the pretreatment state, when the AE is continuous ...
Looking for Furanose? Find out information about Furanose. A sugar whose cyclic or ring structure resembles that of furan. a ring-shaped monosaccharide containing a five-member furan ring. Unlike the six-member... Explanation of Furanose
Background Peripheral neuropathy (PN) is a common toxicity and treatment limiting factor in heavily pretreated patients (pts) with metastatic breast cancer (MBC). Consequently, tolerability is important when choosing treatment. Eribulin mesylate has recently been approved in the US for patients with MBC who have previously received at least two chemotherapeutic regimens for metastatic disease including an anthracycline and a taxane. Eribulin was associated with a 34.6% incidence of PN (7.8% grade 3; 0.4% grade 4), however, over half of pts experiencing grade 3/4 PN continued eribulin. Ixabepilone (IXA) is frequently used in late-line MBC pts and registration studies reported an overall PN incidence of 63% (14-21% grade 3/4). We sought to define incidence of PN of eribulin and IXA in a late-line setting since indirect comparisons suggest eribulin may have a more favorable neurotoxicity profile compared with IXA.. Methods: This randomized, two-arm, multicenter, open-label, phase II study ...
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By hydroboration-oxidation methyl 10-undecenoate, methyl oleate, methyl ricinoleate and methyl linoleate are converted into hydroxy- and dihydroxyesters in 82-92% yield. Hydroboration of oleic acid and subsequent isomerization of the organoborane by heating to 220°C leads after oxidative work-up to 70% of 1,4-octadecanediol. Fatty ester groups of organoboranes can be attached to the carbonyl-equivalent: dichloromethyl methyl ether (DCME) to afford in one step and 55-80% yield dimers of fatty esters with an inserted ketocarbonyl group. ...
Dr. Larry D. Dial has been named associate chief medical officer of Marshall Health. In this position, he will assist Marshalls current chief medical officer, Dr. Joe Werthammer, and will work with the executive management team to ensure the continued success of Marshall Health and the School of Medicine. Dial also will retain his current role as chairman of the department of internal medicine. Dial is a 1999 graduate of the school of medicine and completed a residency in internal medicine at Marshall as well.. I couldnt be more pleased that these two outstanding physicians have accepted new roles for us, said Dr. Joseph I. Shapiro, dean of the school of medicine. As we expand to continue our missions of medical education, research and patient care, its imperative we select leaders whose abilities align with those goals. Both Dr. Becker and Dr. Dial understand where we are going and their vision will help us get there.. The new appointments will be effective Jan. 1.. ...
From the United Kingdom, dial 0800-587-1047; from Australia, dial 1-800-98-7713; from Colombia, dial 01800-5-1-81120; from Netherlands, dial 0800-022-2493; from Peru, dial 0800-52627; from Singapore, dial 800-110-1460; from Saudi, dial 800-844-6984; from U.A.E., dial 8000-444-0538 and from Venezuela, dial 0800-1-00-2128. From Dubai and all other international locations, access an international operator and ask to place an international collect call to the United States. Ask the operator to dial 1-866-235-5687. The call will be placed to the Compliance Hotline.. The CB&I Compliance Hotline is staffed by a live operator from an outside company, 24 hours a day, seven days a week. Calls may be made anonymously. Concerns and complaints will be referred to the appropriate areas within the Company or to the Audit Committee or non-management directors, based on the nature of the call, and will be investigated promptly.. ...
Waters provides magnetic sector and APGC-MS/MS systems for the detection and quantification of dioxins and related compounds at ultra-trace levels.
Rosefuran (3-methyl-2-prenylfuran) is a liquid boiling at 103-104 °C (at 50 mm Hg), with a density of 0.9089 g/cm3 (at 30 °C), less than that of water. It is an aroma chemical which is a minor constituent of the aroma of the rose (Rosa damascene). Rosefuran is a 2,3-disubstituted furan (3-methyl-2-(3-methyl-2-buten-1-yl)furan ...
Photochemical reactions of 2-substituted furans I, IV and V with benzaldehyde, benzophenone and 4-methylbenzophenone gave substitued 2,7-dioxabicyclo[3,2,0]-3-heptenes, which can be used for syntheses of 2,3- or 2,4-disubstituted furans. Regioisomeric (2:1)-cycloadducts XV and XVI were distinguished on the basis of their 1H and 13C NMR spectra.. ...
Catalytic conversions of various furan derivatives[edit]. The third class includes reactions describing the synthesis of FDCA ... The potential applications of furan-based building blocks for polymer applications has been extensively reviewed by Gandini.[20 ... The second class of synthesis routes include the oxidation reactions of various 2,5-disubstituted furans utilizing a variety of ... Furan-2,5-dicarboxylic acid (FDCA) has been suggested as an important renewable building block because it can substitute for ...
Furan, Amy. "Dream Job: Snowplow Driver". salary.com. Archived from the original on 1 May 2007. Retrieved 23 April 2007.. ...
Toxic equivalence factors (TEFs) exist for seven congeners of dioxins, ten furans and twelve PCBs. The reference congener is ... Polychlorinated dibenzofurans (PCDFs), or furans. PCDFs are derivatives of dibenzofuran. There are 135 isomers, ten have dioxin ... in case of dioxins and furans, chlorine substitutes in positions 2,3,7, and 8.[2] Each additional non-lateral chlorine ... "Apparent half-lives of dioxins, furans, and polychlorinated biphenyls as a function of age, body fat, smoking status, and ...
Maga, Joseph A.; Katz, Ira (May 1979). "Furans in foods". C R C Critical Reviews in Food Science and Nutrition. 11 (4): 355-400 ...
1832: Dobereiner produces furfural (a furan) by treating starch with sulfuric acid. 1834: Runge obtains pyrrole ("fiery oil") ... Included are pyridine, thiophene, pyrrole, and furan. Another large class of heterocycles are fused to benzene rings, which for ... "Design, synthesis of novel furan appended benzothiazepine derivatives and in vitro biological evaluation as potent VRV-PL-8a ... pyridine, thiophene, pyrrole, and furan are quinoline, benzothiophene, indole, and benzofuran, respectively. Fusion of two ...
They consist of coumarin annulated with furan. It can also be injected and used topically. Methoxsalen is extracted from Ammi ...
Furan is thus derivable from renewable resources. Applications[edit]. Polymerization[edit]. In the presence of strong acids, ... THF can also be synthesized by catalytic hydrogenation of furan.[8][9] Certain sugars can be converted to THF,[citation needed] ...
In furan, the oxygen atom is sp2 hybridized. One lone pair is in the π system and the other in the plane of the ring (analogous ... This can lessen the ring's aromaticity, and thus (as in the case of furan) increase its reactivity. Other examples include ... to the C-H bond in the other positions). There are 6 π-electrons, so furan is aromatic. Aromatic molecules typically display ...
2. Dien-Synthesen des Furans.)". Annalen. 490 (1): 243-257. doi:10.1002/jlac.19314900110. Van Berkel, Sander S.; Dirks, A. (Ton ... 3-triazoles and furans. The intermediate triazolines avoid detection because of a very strong thermodynamic drive to collapse ... readily obtainable by a Diels-Alder cycloaddition between furans and acetylenedicarboxylates such as DMAD. OND-2,3- ...
The asymmetric hydrogenation of furans and benzofurans has so far proven challenging. Some Ru-NHC complex catalyze asymmetric ... The asymmetric hydrogenation of furans and benzofurans As is the case with oxygen-containing heterocycles, the asymmetric ... Wysocki, Jędrzej; Ortega, Nuria; Glorius, Frank (2014). "Asymmetric Hydrogenation of Disubstituted Furans". Angewandte Chemie ... hydrogenations of benzofurans and furans. with high levels of enantioinduction. ...
The aromatic ethers include furans. Acetals (α-alkoxy ethers R-CH(-OR)-O-R) are another class of ethers with characteristic ...
4-(4-methylsulfonylphenyl)-3-phenyl-5H-furan-2-one. CAS Number. *162011-90-7 Y ...
Furan Gachkun , Gachlu , Gandam Guh , Garakan , Garmab , Gav Khaneh , Gavar , Gavi Cheshmeh , Gavjellu , Gazavand , Gazeran , ...
2017). "Furan". Glottolog 3.0. Jena, Germany: Max Planck Institute for the Science of Human History. ...
... is used to make other furan derivative, such as furoic acid, via oxidation, and furan itself via palladium catalyzed ... Chemically, furfural is an aldehyde of furan. It is a colorless oily liquid with the odor of almonds, which quickly darkens ... Hydrogenation of furfural provides furfuryl alcohol (FA), which is a used to produce furan resin prepolymers exploited in ... "The Furans: Fifteen Years of Progress". Industrial & Engineering Chemistry. 28 (7): 755-759. doi:10.1021/ie50319a002. ISSN 0019 ...
Furan, Amy (2006). "Dream Jobs: Zamboni Driver". Archived from the original on July 5, 2006. Retrieved April 3, 2007 - via ...
2-METHYL-FURAN". Retrieved 2008-08-26. "2-methyl furan". The Good Scents Company. Retrieved 2008-08-26. L. W. Burnette, et al ...
... is a natural terpenoid that consists of a furan ring with a six-carbon side chain containing a ketone functional ... 64: 1130-6. Perilla: Botany, Uses and Genetic Resources Teruo Matsuura (1957). "Natural furan derivatives. I. The synthesis of ...
US patent US4128658, "Aminoalkyl furan derivatives", 1978 *^ Laurence Brunton; John Lazo; Keith Parker (August 2005). Goodman ... Glaxo refined the model further by replacing the imidazole ring of cimetidine with a furan ring with a nitrogen-containing ... N-(2-[(5-[(dimethylamino)methyl]furan-2-yl)methylthio]ethyl)-N'-methyl-2-nitroethene-1,1-diamine ...
These noxious fumes include dioxins and furans. Bonfire refuse can be disposed of quickly into drainage ditches or waterways ...
Wilson, Christopher L. (December 1947). "Reactions of Furan Compounds. VII. Thermal Interconversion of 2,3-Dihydrofuran and ...
Wilson, C. L.; Borchert, A. E. (1947). "Reactions of Furan Compounds. VII. Thermal Interconversionof 2,3-Dihydrofuran and ...
Ramonczai, J.; L. Vargha (June 1950). "Studies of furan compounds. III. A new synthesis of furyl ketones". Journal of the ...
Furan, an oxygen analog. Thiophene, a sulfur analog. Simple aromatic rings Varsol, a petroleum distillate with a boiling range ...
135-234, doi:10.1016/S0065-2725(08)60141-5 W. Friedrichsen (1999), "Recent advances in the chemistry of benzo[c]furans and ... W. Friedrichsen (1980), "Benzo[c]furans", Adv. Heterocycl. Chem. 26: pp. ...
"Palladium-catalyzed asymmetric hydrogenation of furan carboxylic acids". Journal of Catalysis. 219 (1): 52-58. doi:10.1016/ ... "Enantioselective homogeneous hydrogenation of monosubstituted pyridines and furans". Monatshefte fuer Chemie. 131 (12): 1335- ...
Besedilo se sme prosto uporabljati v skladu z dovoljenjem Creative Commons Priznanje avtorstva-Deljenje pod enakimi pogoji 3.0; uveljavljajo se lahko dodatni pogoji. Za podrobnosti glej Pogoje uporabe ...
5H-furan-2-on. Drugi nazivi furan-2-on, γ-krotonolakton, β-anđelika lakton, butenolid ...
These are the furan ring, the ketone group and the alcohol group. The furan ring is aromatic according to Hückel's rule, so the ... It consists of a furan ring, which is substituted at the third carbon of the furan ring with a pentanone containing a hydroxyl ... Furan is heterocyclic, which means that it is cyclic, but one or more of the ring atoms is not a carbon atom. In the case of ... A furan ring is a five-membered aromatic ring consisting of one oxygen atom and four carbon atoms; a pentanone is a ketone ...
Furan Furfural Pyrone Thiopyran Masamune, S.; Castellucci, N. T. (1962). "γ-Pyran". Journal of the American Chemical Society. ...
SGS dioxin and furan analysis can accurately measure trace quantities to improve your site safety. Find out more. ... Toxic dioxins and furans can accumulate through industrial processes. ... Environment Dioxins and Furans. Dioxins and furans are carcinogenic and so are some of the most regulated environmental ... Home › Environment › Air, Noise, Odor and Vibration › Laboratory Analysis › Specialty Analyses › Dioxins and Furans ...
Toxics Link Dioxins and Furans booklet.pdf. Toxics Link Dioxins and Furans booklet.pdf ... Ongoing review and updating of the Standardized Toolkit for Identification and Quantification of Dioxin and Furan Releases - An ...
Get the latest furan contamination news on Environmental XPRT, the worlds largest environmental industry marketplace and ... Keenan is known for his skills in risk assessment of PCBs, dioxins, furans, chromium, and mercury and for the development of ... The sediments are contaminated with high levels of dioxins and furans, chlorobenzenes, metals, and other materials. On June 27 ...
Koi Ha Furan ARO HIROSHI 恋は芙蘭 - あろひろし/著 ...
110-00-9 Furan (furane) testing. Laboratory testing for CAS number 110-00-9. Divinylene oxide;Furfuran;Oxacyclopentadiene;Oxole ... Tetrole;Furane;Furfurane;NCI-C56202;Rcra waste number U124;UN 2389;QO Furan. This chemical is colourless liquid ... Alternate Names: Furan , FURAN. Department: Organics. * Columbia Analytical may or may not test for the presence of Furan ( ... Furan (furane) - CAS # 110-00-9. Information provided on Furan (furane) (110-00-9) is for reference only and is subject to ...
... words that start with furans, words that end with furans, anagrams of furans, how to spell furans!, Words with Friends, ... Anagrams and words you can make with the letters in furans ( a f n r s u ). Words that end with furans. furans. ... furanosides : furans : furazolidone Words that sound like or rhyme with furans. burans furanes puranas francs franks pyrans ... See what words contain the exact word furans. ... Suffixes of furans. urans rans ans ns Prefixes of furans. furan ...
Furan 27.5". Hard knuckle mountain riding is Furans forte. Hand welded from 6061 Aluminum, Psynydes specially designed ... The Furan will perform well with 100 mm fork travel as well. A higher travel fork will put the frame integrity at risk. ... The Furan will perform well with 100 mm fork travel as well. A higher travel fork will put the frame integrity at risk. ... Our Furan frame is available to customers as a frame only option. This is a great way to experience the Psynyde Design ...
Psynyde Furan 27.5"-Deore Build. PsynydeFuran27.5Deore Build The Furan is a 650B Trail & Single track Bike which features short ... Psynyde Furan 27.5"-Deore Build. Home / Bicycles / MTB / Psynyde Furan 27.5"-Deore Build. ... Be the first to review "Psynyde Furan 27.5"-Deore Build" Cancel reply. Your email address will not be published. Required ... The 800mm wide bar and 50mm stem combination allows Furan to maneuver over some of the most technical terrain with ease. ...
Furan is used as a starting point to other speciality chemicals. The name "furan" comes from the Latin furfur, which means bran ... Furan is therefore listed as a possible human carcinogen. BS 4994 - Furan resin as thermoset FRP for chemical process plant ... Many routes exist for the synthesis of substituted furans. Furan is aromatic because one of the lone pairs of electrons on the ... Hydrogenation of furans sequentially affords dihydrofurans and tetrahydrofurans. In the Achmatowicz reaction, furans are ...
Furan, the chemical industrial compound Polychlorinated dibenzofurans, an unintentional contaminant byproduct of furans Furan ( ... river) in France Furan, Iran, a village in Markazi Province, Iran Nitrofurantoin, by the trade name Furan. ...
... and application of furans and benzofurans bearing a fluorine atom and a trifluoromethyl group are reviewed. ... Lyalin VV, Grigorash RV, Alekseeva LA, Yagupolskii LM (1975) Mono(trifluoromethyl)furans and bis(trifluoromethyl)furans. Russ J ... Wilson WS, Warrener RN (1972) A mild retro-[π4S+π2S] cleavage route to furans and fulvenes. J Chem Soc Chem Commun 211-212 ... Palladium-catalyzed alkenylation of fluoro-substituted furans via C-H activation to form tetrasubstituted furans. Tetrahedron ...
furans This website has limited functionality with javascript off. Please make sure javascript is enabled in your browser. ... For references, please go to https://www.eea.europa.eu/help/glossary/eea-glossary/furans or scan the QR code. ...
Body burden levels of dioxin, furans, and PCBs among frequent consumers of Great Lakes sport fish. The Great Lakes Consortium. ... Table of laboratory methods panels for Dioxins, Furans, coplanar polychlorinated biphenyls (PCBs). Chemical. Specimen Type. ... Biomonitoring Factsheet: Dioxins, Furans and Dioxin-Like Polychlorinated Biphenyls. National Report on Human Exposure to ... On the isolation of polychlorinated dibenzo-p-dioxins and furans from serum samples using immunoaffinity chromatography prior ...
The purpose of this technical report is to present the IDLH value for furan (CAS® #110-00-9). ... The purpose of this technical report is to present the IDLH value for furan (CAS® #110-00-9). The scientific basis, toxicologic ... Immediately Dangerous to Life or Health (IDLH) Value Profile: Furan. ...
APGC-MS/MS Investigation of a Complex Mixture of Polyhalogenated Dioxins and Furans (PXDD/Fs) Generated in Fire Debris ...
EHP is pleased to present the abstracts from the 29th Annual Scientific Conference of the International Society for Environmental Epidemiology (ISEE), held in Sydney, Australia, 24-28 September 2017. The conference was hosted by The University of Sydney and cosponsored by the Woolcock Institute of Medical Research, with the theme "Healthy Places, Healthy People-Where Are the Connections?". ...
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Green J.H.S., Spectroscopic and thermodynamic properties of furan derivatives. I. 2- and 2,5-substituted compounds, Spectrochim ... Energy storage capacity of reversible liquid-phase Diels Alder reaction between maleic anhydride and 2-methyl furan, Am. Inst. ...
Other names: 2-Propylfuran; Furan, «alpha»-propyl-; 2-n-Propylfuran * Permanent link for this species. Use this link for ...
The name "furan" comes from the Latin furfur, which means bran.[5] The first furan derivative to be described was 2-furoic acid ... Synthesis of furansEdit. The Feist-Benary synthesis is a classic way to synthesize furans, although many syntheses have been ... For other uses, see Furan (disambiguation).. Furan is a heterocyclic organic compound, consisting of a five-membered aromatic ... Hydrogenation of furans sequentially affords dihydrofurans and tetrahydrofurans.. *In the Achmatowicz reaction, furans are ...
Dioxins, Furans, & Coplanar PCBs (L28DFP_C) Data File: L28DFP_C.xpt First Published: April 2008. Last Revised: NA ... Together with the polychlorinated dioxins and furans, these two special classes of PCBs are often referred to as "dioxin-like" ...
2005) Furan fatty acids: Occurrence, synthesis, and reactions. Are furan fatty acids responsible for the cardioprotective ... Furan fatty acids. Rachelle A. S. Lemke, Amelia C. Peterson, Eva C. Ziegelhoffer, Michael S. Westphall, Henrik Tjellström, ... Furan fatty acids. Rachelle A. S. Lemke, Amelia C. Peterson, Eva C. Ziegelhoffer, Michael S. Westphall, Henrik Tjellström, ... 2011) Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus. Proc Natl Acad Sci USA ...
Altogether, our study shows that BVMOs can be employed for the selective oxidation of furans. ... were selected for studying their biocatalytic potential in converting furfural and some other furans. While BVMOs are usually ... can be used as biocatalysts for the selective oxidation of several furans, including 5-(hydroxymethyl) furfural (HMF) and ... Various furans are considered as valuable platform chemicals as they can be derived from plant biomass. Yet, for their ...
Find furan sampling articles on Environmental XPRT, the worlds largest environmental industry marketplace and information ... furan sampling Articles. Related terms for "furan sampling ": furan articles , furan sampling system articles , long-term furan ... Dioxins and Furans on the Equity-5 Dioxins and furans are byproducts of several different industrial processes, including ... Paper fibers as a carbon source for the de novo formation of polychlorinated dioxins and furans Abstract The formation of ...
P. putida ALS1267 was the most tolerant to furans and tolerated 17 mM furfural or 195 mM furoate before its growth rate was ... Wang, X., Miller, E. N., Yomano, L. P., Shanmugam, K. T., & Ingram, L. O. (2012). Increased furan tolerance in Escherichia coli ... Isolation and Characterization of Bacteria That Use Furans as the Sole Carbon Source. ...
Furans have one or two phenyl rings connected to a furan ring. PCBs have two phenyl rings attached at one point. One or more ... Dioxins, Furans, PCBs (contain phenyl rings of carbon atoms). Dioxins, furans, and polychlorinated biphenyls (PCBs) are a class ... Dioxins and dioxin-like furans have no known commercial or natural use. They are produced primarily during the incineration or ...
Change in dioxin and furan emissions This website has limited functionality with javascript off. Please make sure javascript is ... 20environment/change-in-dioxin-furan-emissions or scan the QR code. ...
Furans have one or two phenyl rings connected to a furan ring. PCBs have two phenyl rings attached at one point. One or more ... Dioxins, Furans, PCBs (contain phenyl rings of carbon atoms). Dioxins, furans, and polychlorinated biphenyls (PCBs) are a class ... Dioxins and dioxin-like furans have no known commercial or natural use. They are produced primarily during the incineration or ...
Consumer exposure to furan and methylfurans in food could lead to possible long-term liver damage. The most exposed group of ... Reducing furan exposure. Furans form from a variety of substances naturally present in food, including vitamin C, carbohydrates ... Potential health risks linked to furan. EFSA carried out this assessment following its monitoring of furan levels in food and ... The level of furan in toast increases with toasting time and with the degree of browning, albeit toast is a less important ...
... "furan levels alone do not equate to furan exposure; calculating exposure requires consideration of both furan levels, and the ... "Exploratory Data on Furan in Food: Individual Food Products" See also "Questions and Answers on the Occurrence of Furan in Food ... Furans can be found in a multitude of heat processed food products- many of which do not contain high fructose corn syrup. To ... Misleading Study on Furans and High Fructose Corn Syrup. FOR IMMEDIATE RELEASE. May 14, 2010 ...
Ime furan izhaja iz latinske besede furfur, ki pomeni otrobe.[1] Prvi opis derivata furana je bila 2-furojska kislina, ki jo je ... Furan sam je kot prvi pripravil Heinrich Limpricht leta 1870, čeprav mu je rekel tetrafenol.[2][3] ... Furan je heterociklična organska spojina, ki jo sestavlja petčlenski aromatski obroč s štirimi atomi ogljika in enim atomom ... Furan je brezbarvna, vnetljiva, izjemno hlapljiva tekočina z vreliščem blizu sobne temperature. Je strupen, morda tudi ...
... successfully completed an engine test to demonstrate the potential of its furan-based biofuels, or ... Avantium Engine-Tests Furan-Based Biofuel 26 October 2007 Avantium derives its Furanics fuels from the intermediate ... Well, the furans might be good fuels. But the real problem here is to get them cheaply on large scale. You get them from ... In furan production, the feedstock can only be sugars (luckily, we have a lot of sugars in any plant material). ...
  • Dioxins and furans are carcinogenic and so are some of the most regulated environmental contaminants. (sgs.com)
  • Produced inadvertently by industrial processes such as waste incineration, chemical manufacturing and paper bleaching, dioxins and furans can be found in the air, in water and contaminated soil. (sgs.com)
  • High-resolution mass spectrometry is the only legally accepted analytical technique for quantifying dioxins and furans. (sgs.com)
  • The sediments are contaminated with high levels of dioxins and furans, chlorobenzenes, metals, and other materials. (environmental-expert.com)
  • Call SGS today for a dioxin and furan analysis to ensure your site safety. (sgs.com)
  • Our dioxin and furan testing can identify where toxic emissions are occurring and help to improve the safety of your operations. (sgs.com)
  • We also monitor dioxin and furan levels in food and animal feed. (sgs.com)
  • Fully accredited at local and international level, we are recognized as one of the world's leading and most reliable laboratories for dioxin and furan testing. (sgs.com)
  • About ranitidinea histamine h2-receptor antagonist, furan derivative, anti-secretory g.i agent,anti ulcer.mechanism of action of ranitidineranitidine is a h2 (histamine) receptor antagonist. (dalilaldwaa.com)
  • Dioxins and furans are carcinogenic and so are some of the most regulated environmental contaminants. (sgs.com)
  • Produced inadvertently by industrial processes such as waste incineration, chemical manufacturing and paper bleaching, dioxins and furans can be found in the air, in water and contaminated soil. (sgs.com)
  • High-resolution mass spectrometry is the only legally accepted analytical technique for quantifying dioxins and furans. (sgs.com)
  • The process of smashing and burning the plastic casing and cables, to extract the metals, releases dangerous chemicals found within the plastics, such as brominated flame retardants, and creates highly toxic by-product chemicals like brominated and chlorinated dioxins and furans. (ipen.org)
  • Together with the polychlorinated dioxins and furans, these two special classes of PCBs are often referred to as "dioxin-like" chemicals because they act in the body through a similar mechanism. (cdc.gov)
  • The sediments are contaminated with high levels of dioxins and furans, chlorobenzenes, metals, and other materials. (environmental-expert.com)
  • Dioxins and furans are byproducts of several different industrial processes, including incineration and paper bleaching. (environmental-expert.com)
  • Polychlorinated dibenzo dioxins (PCDDs) and polychlorinated dibenzo furans (PCDFs) are persistent organic pollutants (POPs) banned by the Stockholm Convention and they are therefore monitored worldwide. (environmental-expert.com)
  • The efficacy of pressurized solvent extraction with BUCHI's new SpeedExtractor was examined for the extraction of dioxins/furans (PCDDs/PCDFs), polybrominated diphenyl ethers (PBDEs), and perfluorinated compounds (PFCs) from different environmental matrices: PCDDs/PCDFs from soil samples, PFCs from soil and sewage sludge, and PBDEs from lake sediments. (environmental-expert.com)
  • Car-engine air filters (CAFs) have been recently used as inexpensive alternative air sampling media for hydrophobic organic compounds such as polycyclic aromatic hydrocarbons, polychlorinated dibenzo-p-dioxins and furans and also for heavy metals. (environmental-expert.com)
  • Dioxins, furans, and polychlorinated biphenyls (PCBs) are a class of similar chlorinated aromatic organic compounds. (cdc.gov)
  • Dioxins and dioxin-like furans have no known commercial or natural use. (cdc.gov)
  • Please explore our range of standards for dioxins and furans below and get in touch if you have questions about how we can support you in your analytical testing. (lgcstandards.com)
  • We identify and quantify ultra-trace levels of Dioxins, Furans and Dioxin-like PCB congeners and other persistent organic pollutants (POPS) in liquid, solid, air and biota. (maxxam.ca)
  • In selecting a 'supplier' for analysis of dioxins and furans and dioxin-like PCB congeners, it is important to realize that services differ from lab to lab in terms of analytical solutions provided, instrumentation used and the expertise of the people involved in the project. (maxxam.ca)
  • As part of environmental health studies in Escambia and Santa Rosa counties, UWF's CEDB found that blue crabs and oysters collected from western Escambia Bay locations had relatively higher loads (TEQs) of dioxins/furans and dioxin-like PCBs than samples collected from eastern Escambia Bay. (uwf.edu)
  • Recent findings indicate that mullet and large mouth bass collected from Lower Escambia River contain relatively high concentrations of total PCBs and dioxins/furans/dioxin-like PCBs. (uwf.edu)
  • Because of the paucity of information on sediment contamination in the Escambia Bay system, notably the limited spectrum of past analyses for PCB congeners and none for dioxins/furans, it is difficult to ascertain the geographical extent and levels of these toxic chemicals in the bay. (uwf.edu)
  • This project will determine the levels of PCBs (complete congener profiles) and dioxins/furans in sediment samples taken at 20 locations in the Escambia Bay, including some sites in the Lower Escambia River. (uwf.edu)
  • This study provides suggestive evidence that average serum concentrations of dioxins, furans, and PCBs are decreasing over time among residents of this town. (biomedcentral.com)
  • Dioxins and furans in sewage sludges : a review of their occurrence and possible sources in sludge and of their environmental fate, behaviour and significance in sludge-amended agricultural systems. (lancs.ac.uk)
  • Dioxins and furans in sewage sludges : a review. (lancs.ac.uk)
  • Polychlorinated dibenzo-p-dioxins and-furans (PCDD/Fs) are two groups of organic compounds that are ubiquitous in the environment at ultratrace levels, but that have attracted considerable scientific and political concern because of their environmental persistence, tendency to bioaccumulate through the foodchain, and toxicity. (lancs.ac.uk)
  • Synthesis, reactions, and application of furans and benzofurans bearing a fluorine atom and a trifluoromethyl group are reviewed. (springer.com)
  • The Feist-Benary synthesis is a classic way to synthesize furans, although many syntheses have been developed. (wikipedia.org)
  • One of the simplest synthesis methods for furans is the reaction of 1,4-diketones with phosphorus pentoxide (P2O5) in the Paal-Knorr synthesis. (wikipedia.org)
  • Many routes exist for the synthesis of substituted furans. (wikipedia.org)
  • The reaction product is a mixture of isomers with preference for the endo isomer: Diels-Alder reaction of furan with arynes provides corresponding derivatives of dihydronaphthalenes, which are useful intermediates in synthesis of other polycyclic aromatic compounds. (wikipedia.org)
  • Considerable attention has been focused on the synthesis of furan derivatives and screening them for pharmacological activity. (sigmaaldrich.com)
  • Diels-Alder reaction of furan with arynes provides corresponding derivatives of dihydronaphthalenes , which are useful intermediates in synthesis of other polycyclic aromatic compounds . (wikipedia.org)
  • This paper reports on the occurrence and synthesis of a newly discovered class of furan-containing fatty acid. (pnas.org)
  • A new strategy for cyclopenta[ b ]furan synthesis mediated by hypervalent iodine(III) has been described. (mdpi.com)
  • Chuang, T.-H. Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[ b ]furans. (mdpi.com)
  • Synthesis, anthelmintic and antiacetylcholinesterase activity of newer furan derivatives. (ijpsonline.com)
  • An efficient CuI-catalyzed coupling cyclization of gem -difluoroalkenes with active methylene carbonyl compounds such as 1,3-dicarbonyl compounds, acetoacetonitrile, and phenylsulfonylacetone enables the synthesis of 2,3,5-trisubstituted furans with the assistance of a base. (organic-chemistry.org)
  • Very good isolated yields, and excellent functional group compatibility make this transformation a powerful tool for the synthesis of various furans. (organic-chemistry.org)
  • Palladium catalysis enables a highly efficient synthesis of a wide range of 2,5-disubstituted furans in very good yields from enyne acetates in the presence of a Lewis acid. (organic-chemistry.org)
  • Chapter 1 reviews the recent advances in the field of palladium catalyzed synthesis of bicyclic furan analogs and provides a mechanistic explanation for these processes. (usf.edu)
  • Chapter 2 describes synthesis of new optically pure isoxazoline-2-oxide and furan analogs using Pd(0) catalyzed intramolecular cyclizations. (usf.edu)
  • Khan, Pasha Moeenuddin, "Application of Pd catalyzed alkylation: Synthesis of bicyclic furans, isoxazolines and new cyclopentane amino acid analogs" (2008). (usf.edu)
  • Penn furan and furfural based solvents offer unique capabilities as starting materials for the synthesis of pharmaceutical, agricultural, and industrial chemicals. (chempoint.com)
  • Results: Among the various ionic resins attempted, Amberlyst-15® in PEG-400 was the choice of selection for the synthesis of 3-benzoyl-5-hydroxy benzofuran and naphtho[1,2-b]furan derivatives at room temperature in an environmentally friendly method. (eurekaselect.com)
  • Industrially, furan is manufactured by the palladium-catalyzed decarbonylation of furfural, or by the copper-catalyzed oxidation of 1,3-butadiene: In the laboratory, furan can be obtained from furfural by oxidation to 2-furoic acid, followed by decarboxylation. (wikipedia.org)
  • In the laboratory, furan can be obtained from furfural by oxidation to 2-furoic acid, followed by decarboxylation . (wikipedia.org)
  • Here we demonstrate that Baeyer-Villiger monooxygenases (BVMOs) can be used as biocatalysts for the selective oxidation of several furans, including 5-(hydroxymethyl) furfural (HMF) and furfural. (mdpi.com)
  • Phenylacetone monooxygenase (PAMO) and a mutant thereof (PAMO M446G ) were selected for studying their biocatalytic potential in converting furfural and some other furans. (mdpi.com)
  • P. putida ALS1267 was the most tolerant to furans and tolerated 17 mM furfural or 195 mM furoate before its growth rate was reduced by 50 % in a defined medium. (springer.com)
  • Body burden levels of dioxin, furans, and PCBs among frequent consumers of Great Lakes sport fish. (cdc.gov)
  • It is submitted in the Court that the Central Pollution Control Board does not have in-house mechanism in their laboratories to analyse Dioxin and Furans. (org.in)
  • Furan is a heterocyclic organic compound, consisting of a five-membered aromatic ring with four carbon atoms and one oxygen. (wikipedia.org)
  • Furan is a heterocyclic organic compound produced in the chemical manufacturing industry and also found in a broad range of food products, including infant formulas and baby foods. (nih.gov)
  • The ceric ammonium nitrate oxidation of the furo(3,2-b]naphtho[2,l-d]furan-8(9H)- ones (5c,5d) gave the rearranged hemiketals (llc,lld) in 72-76% yield. (auckland.ac.nz)
  • Furan is therefore listed as a possible human carcinogen. (wikipedia.org)
  • Furans form from a variety of substances naturally present in food, including vitamin C, carbohydrates, amino acids, unsaturated fatty acids and carotenoids. (europa.eu)
  • The study, published in the October, 2004 issue of Journal of Agricultural and Food Chemistry , shows how food-based amino acids and sugars break down when heated to produce furan. (bio-medicine.org)
  • The report generally describes 2-amino-1-furan-2-yl-ethanol, examines its uses, production methods, patents. (marketpublishers.com)
  • 2-amino-1-furan-2-yl-ethanol manufacturers and suppliers with contacts and product range are mentioned in the study. (marketpublishers.com)
  • Furthermore, 2-amino-1-furan-2-yl-ethanol prices in regional markets can be found in the report with regards to countries and companies. (marketpublishers.com)
  • The report also focuses on 2-amino-1-furan-2-yl-ethanol consumers by providing data on companies that use it. (marketpublishers.com)
  • 2-AMINO-1-FURAN-2-YL-ETHANOL (CAS 2745-22-4) Market Research Report 2017 contents were worked out and placed on the website in December, 2017. (marketpublishers.com)
  • Please note that 2-AMINO-1-FURAN-2-YL-ETHANOL (CAS 2745-22-4) Market Research Report 2017 is a half ready publication and contents are subject to change. (marketpublishers.com)
  • We provide independent and unbiased information on manufacturers, prices, production news and consumers for the global and regional (North America, Asia and Europe) market of {[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid. (reportsnreports.com)
  • The main emphasis of this work is to utilize Pd catalyzed allylic alkylation to synthesize new heterocycles including furans, isoxazolines and new cyclopentane amino-acid analogs in an enantioselective manner. (usf.edu)
  • The crystal and molecular structure of 6-bromo-2-(furan-2-yl)-3-(prop-2-ynyl)-3H-imidazo[4,5-b]pyridine (C 13 H 8 BrN 3 O) has been investigated from single crystal X-ray diffraction data. (hindawi.com)
  • In this work, we have synthesized the 3-prop-2-ynyl analogue which is 6-bromo-2-(furan-2-yl)-3-(prop-2-ynyl)-3H-imidazo[4,5-b]pyridine ( 1 ) (Scheme 1 ). (hindawi.com)
  • Furans have one or two phenyl rings connected to a furan ring. (cdc.gov)
  • In the title compound, C 21 H 14 F 2 O 2 S, the dihedral angles between the mean plane [r.m.s. deviation = 0.007 (2) Å] of the benzo-furan ring system and the pendant 4-fluoro-phenyl and phenyl rings are 5.93 (9) and 80.23 (5)°, respectively. (iucr.org)
  • In November 2016, the EMCDDA and Europol examined the available information on a new psychoactive substance N -phenyl- N -[1-(2-phenylethyl)piperidin-4-yl]-furan-2-carboxamide, commonly known as furanylfentanyl, through a joint assessment. (europa.eu)
  • In the central fragment, consisting of two fused tetra-hydro-furan rings, one O atom and its two adjacent C atoms, a methyl-ene and a bridgehead C atom, are disordered over two sets of sites with an occupancy ratio of 0.735 (9):0.265 (9). (iucr.org)
  • 1. 2-methyl furan is widely used as solvent. (guidechem.com)
  • 2. Our 2- methyl furan annual output is 5000MT. (guidechem.com)
  • Exposure to furan at doses about 2000 times the projected level of human exposure from foods increases the risk of hepatocellular tumors in rats and mice and bile duct tumors in rats. (wikipedia.org)
  • Consumer exposure to furan and methylfurans in food could lead to possible long-term liver damage. (europa.eu)
  • EFSA carried out this assessment following its monitoring of furan levels in food and assessing consumer exposure. (europa.eu)
  • As did the Joint FAO/WHO Expert Committee on Food Additives [JECFA], we concluded that the level of exposure to furan in food indicates a human health concern. (europa.eu)
  • Although the average intake of foods containing furan indicates a low health concern for most consumers, for high consumers exposure is up to three times what would be considered of low concern for public health. (europa.eu)
  • There are some knowledge gaps about the toxicity of furan and methylfurans and about exposure to them. (europa.eu)
  • Dr Knutsen said: "Our opinion describes how cooking practices could reduce dietary exposure to furan and methylfurans, bearing in mind that consumers are exposed to them in a variety of foods. (europa.eu)
  • The level of furan in toast increases with toasting time and with the degree of browning, albeit toast is a less important contributor to overall furan exposure. (europa.eu)
  • calculating exposure requires consideration of both furan levels, and the amounts of food that consumers eat. (corn.org)
  • The agency also notes that their estimates of consumer exposure to furan is "well below what FDA expects would cause harmful effects. (corn.org)
  • It has been estimated that coffee consumption may be the highest contributor to furan exposure from dietary sources among adults. (oreilly.com)
  • The ' Global and Chinese Tetrahydro-2-Furan Methanol Industry, 2011-2021 Market Research Report ' is a professional and in-depth study on the current state of the global Tetrahydro-2-Furan Methanol industry with a focus on the Chinese market. (marketresearch.com)
  • The report provides key statistics on the market status of the Tetrahydro-2-Furan Methanol manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.Firstly, the report provides a basic overview of the industry including its definition, applications and manufacturing technology. (marketresearch.com)
  • Through the statistical analysis, the report depicts the global and Chinese total market of Tetrahydro-2-Furan Methanol industry including capacity, production, production value, cost/profit, supply/demand and Chinese import/export. (marketresearch.com)
  • The report then estimates 2016-2021 market development trends of Tetrahydro-2-Furan Methanol industry. (marketresearch.com)
  • In the end, the report makes some important proposals for a new project of Tetrahydro-2-Furan Methanol Industry before evaluating its feasibility. (marketresearch.com)
  • Overall, the report provides an in-depth insight of 2011-2021 global and Chinese Tetrahydro-2-Furan Methanol industry covering all important parameters. (marketresearch.com)
  • 5.2 Market Competition of Tetrahydro-2-Furan Methanol Industry by Country (USA, EU, Japan, Chinese etc. (marketresearch.com)
  • The thiophene formation reaction of 1,4-diketones with Lawesson's reagent also forms furans as side products. (wikipedia.org)
  • Furan is a highly volatile compound present in many foods and drinks as a result of thermal treatment during processing. (oreilly.com)
  • Furan itself was first prepared by Heinrich Limpricht in 1870, although he called it "tetraphenol" (as if it were a four-carbon analog to phenol, C6H6O). (wikipedia.org)
  • Avantium, which spun-off from Shell in 2000, successfully completed an engine test to demonstrate the potential of its furan-based biofuels, or "furanics. (greencarcongress.com)
  • Furan a potentially dangerous chemical. (bio-medicine.org)
  • Furan, a potentially dangerous chemical has been found by Health Canada and the U.S. Food and Drug Administration (FDA) in processed foods, especially canned or bottled foods. (bio-medicine.org)
  • Normally, furan is a volatile chemical which tends to quickly evaporate. (bio-medicine.org)
  • TIANFUCHEM-- 4282-32-0 --High purity Dimethyl Furan-2,5-dicarboxylate factory price price,buy Formaldehyde,Formaldehyde supplier-Henan Tianfu Chemical Co., Ltd. (lookchem.com)
  • Furans or All Furans to refine by category, grade, purity, and various physical properties. (sigmaaldrich.com)
  • Different preparation methods for coffee result in different losses of furan concentrations. (europa.eu)
  • Furan is a colorless, flammable, highly volatile liquid with a boiling point close to room temperature. (wikipedia.org)
  • Altogether, our study shows that BVMOs can be employed for the selective oxidation of furans. (mdpi.com)
  • Tailored photo-oxidation of the pro-reactive furan moiety is ensured by the simultaneous introduction of a weak photosensitizer as well as a nucleophilic moiety in the reacting PNA strand. (rsc.org)
  • Here, we show the first example of a visible light-triggered templated ligation on a surface, employing furan-modified peptide nucleic acids (PNAs). (rsc.org)
  • Furan is present in coffee as part of the volatile aroma components generated during roasting of green coffee beans. (oreilly.com)
  • Various furans are considered as valuable platform chemicals as they can be derived from plant biomass. (mdpi.com)
  • This increased understanding of the transformation of DMF and ethylene to p -xylene will aid in the development of a variety of renewable aromatics from biomass derived furans. (umass.edu)
  • Wood ducks were sensitive to dioxin and furan contamination, and we recommend it as an indicator species for monitoring biological impacts from these contaminants. (usgs.gov)
  • Male F344 rats were treated by gavage 5 days per week with 8 mg furan/kg body weight (bw)/day for 90 days. (nih.gov)
  • 1 group of rats was sacrificed 24 h after the last treatment, whereas other groups were maintained without further furan treatment for an additional 90, 180, or 360 days. (nih.gov)
  • Furan is aromatic because one of the lone pairs of electrons on the oxygen atom is delocalized into the ring, creating a 4n + 2 aromatic system (see Hückel's rule) similar to benzene. (wikipedia.org)
  • wherein the molar ratio of 2,5-furan dicarboxylic acid to at least one of the polyfunctional aromatic acid or the hydroxy acid is in the range of 1 : 100 to 100: 1 , and wherein the molar ratio of diol to total acid content is in the range of 1 .2: 1 to 3: 1. (sumobrain.com)
  • It captures 3-[5-(3-hydroxy-propyl)-furan-2-yl]-propan-1-ol market trends, pays close attention to 3-[5-(3-hydroxy-propyl)-furan-2-yl]-propan-1-ol manufacturers and names suppliers. (marketpublishers.com)
  • Our dioxin and furan testing can identify where toxic emissions are occurring and help to improve the safety of your operations. (sgs.com)
  • For references , please go to https://www.eea.europa.eu/data-and-maps/daviz/eionet/sandbox/LOT2%20-%20Daviz%20testing%20environment/change-in-dioxin-furan-emissions or scan the QR code. (europa.eu)