Functional laterality. Medical search

Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.

Dominance of one cerebral hemisphere over the other in cerebral functions.

The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.

A congenital abnormality in which organs in the THORAX and the ABDOMEN are opposite to their normal positions (situs solitus) due to lateral transposition. Normally the STOMACH and SPLEEN are on the left, LIVER on the right, the three-lobed right lung is on the right, and the two-lobed left lung on the left. Situs inversus has a familial pattern and has been associated with a number of genes related to microtubule-associated proteins.

The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.

The dorsal posterior subdivision of the diencephalon. The epithalamus is generally considered to include the habenular nuclei (HABENULA) and associated fiber bundles, the PINEAL BODY, and the epithelial roof of the third ventricle. The anterior and posterior paraventricular nuclei of the thalamus are included with the THALAMIC NUCLEI although they develop from the same pronuclear mass as the epithalamic nuclei and are sometimes considered part of the epithalamus.

Abnormal thoracoabdominal VISCERA arrangement (visceral heterotaxy) or malformation that involves additional CONGENITAL HEART DEFECTS (e.g., heart isomerism; DEXTROCARDIA) and/or abnormal SPLEEN (e.g., asplenia and polysplenia). Irregularities with the central nervous system, the skeleton and urinary tract are often associated with the syndrome.

The species Delphinapterus leucas, in the family Monodontidae, found primarily in the Arctic Ocean and adjoining seas. They are small WHALES lacking a dorsal fin.

A small protuberance at the dorsal, posterior corner of the wall of the THIRD VENTRICLE, adjacent to the dorsal THALAMUS and PINEAL BODY. It contains the habenular nuclei and is a major part of the epithalamus.

A family of rat kangaroos found in and around Australia. Genera include Potorous and Bettongia.

Signaling ligands that act in opposition to NODAL PROTEIN. During vertebrate development they regulate the degree of left-right asymmetry by controlling the spatiotemporal influence of NODAL PROTEIN.

Tests for central hearing disorders based on the competing message technique (binaural separation).

An exotic species of the family CYPRINIDAE, originally from Asia, that has been introduced in North America. They are used in embryological studies and to study the effects of certain chemicals on development.

A verbal or nonverbal means of communicating ideas or feelings.

A group of islands in Melanesia constituting a French overseas territory. The group includes New Caledonia (the main island), Ile des Pins, Loyalty Island, and several other islet groups. The capital is Noumea. It was discovered by Captain Cook in 1774 and visited by various navigators, explorers, and traders from 1792 to 1840. Occupied by the French in 1853, it was set up as a penal colony 1864-94. In 1946 it was made a French overseas territory. It was named by Captain Cook with the 5th and 6th century A.D. Latin name for Scotland, Caledonia. (From Webster's New Geographical Dictionary, 1988, p830 & Room, Brewer's Dictionary of Names, 1992, p375)

Proteins obtained from the ZEBRAFISH. Many of the proteins in this species have been the subject of studies involving basic embryological development (EMBRYOLOGY).

A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.

Populations of thin, motile processes found covering the surface of ciliates (CILIOPHORA) or the free surface of the cells making up ciliated EPITHELIUM. Each cilium arises from a basic granule in the superficial layer of CYTOPLASM. The movement of cilia propels ciliates through the liquid in which they live. The movement of cilia on a ciliated epithelium serves to propel a surface layer of mucus or fluid. (King & Stansfield, A Dictionary of Genetics, 4th ed)

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

Artery formed by the bifurcation of the BASILAR ARTERY. Branches of the posterior cerebral artery supply portions of the OCCIPITAL LOBE; PARIETAL LOBE; inferior temporal gyrus, brainstem, and CHOROID PLEXUS.

A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)

Common name for the largest birds in the order PASSERIFORMES, family Corvidae. These omnivorous black birds comprise most of the species in the genus Corvus, along with ravens and jackdaws (which are often also referred to as crows).

Substances and materials manufactured for use in various technologies and industries and for domestic use.

Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.

An autosomal recessive disorder characterized by a triad of DEXTROCARDIA; INFERTILITY; and SINUSITIS. The syndrome is caused by mutations of DYNEIN genes encoding motility proteins which are components of sperm tails, and CILIA in the respiratory and the reproductive tracts.

The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.

A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.

A spectrum of septal defects involving the ATRIAL SEPTUM; VENTRICULAR SEPTUM; and the atrioventricular valves (TRICUSPID VALVE; BICUSPID VALVE). These defects are due to incomplete growth and fusion of the ENDOCARDIAL CUSHIONS which are important in the formation of two atrioventricular canals, site of future atrioventricular valves.

The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Movement of a part of the body for the purpose of communication.

Tests designed to assess language behavior and abilities. They include tests of vocabulary, comprehension, grammar and functional use of language, e.g., Development Sentence Scoring, Receptive-Expressive Emergent Language Scale, Parsons Language Sample, Utah Test of Language Development, Michigan Language Inventory and Verbal Language Development Scale, Illinois Test of Psycholinguistic Abilities, Northwestern Syntax Screening Test, Peabody Picture Vocabulary Test, Ammons Full-Range Picture Vocabulary Test, and Assessment of Children's Language Comprehension.

A new pattern of perceptual or ideational material derived from past experience.

The ability to differentiate tones.

Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Tumors or cancer of the RETINA.

The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.

The measurement of magnetic fields over the head generated by electric currents in the brain. As in any electrical conductor, electric fields in the brain are accompanied by orthogonal magnetic fields. The measurement of these fields provides information about the localization of brain activity which is complementary to that provided by ELECTROENCEPHALOGRAPHY. Magnetoencephalography may be used alone or together with electroencephalography, for measurement of spontaneous or evoked activity, and for research or clinical purposes.

The process whereby auditory stimuli are selected, organized, and interpreted by the organism.

Dyneins that are responsible for ciliary and flagellar beating.

A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

A condition of an inequality of refractive power of the two eyes.

Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.

A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Use of sound to elicit a response in the nervous system.

Common name for perch-like fish of the family Cichlidae, belonging to the suborder Labroidei, order PERCIFORMES.

The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.

Proteins obtained from various species of Xenopus. Included here are proteins from the African clawed frog (XENOPUS LAEVIS). Many of these proteins have been the subject of scientific investigations in the area of MORPHOGENESIS and development.

A light-sensitive neuroendocrine organ attached to the roof of the THIRD VENTRICLE of the brain. The pineal gland secretes MELATONIN, other BIOGENIC AMINES and NEUROPEPTIDES.

Motion of an object in which either one or more points on a line are fixed. It is also the motion of a particle about a fixed point. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.

The coordination of a sensory or ideational (cognitive) process and a motor activity.

Any of the large interior organs in any one of the three great cavities of the body, especially in the abdomen.

Formation of differentiated cells and complicated tissue organization to provide specialized functions.

Bony structure of the mouth that holds the teeth. It consists of the MANDIBLE and the MAXILLA.

A front limb of a quadruped. (The Random House College Dictionary, 1980)

Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.

The middle germ layer of an embryo derived from three paired mesenchymal aggregates along the neural tube.

Paired, segmented masses of MESENCHYME located on either side of the developing spinal cord (neural tube). Somites derive from PARAXIAL MESODERM and continue to increase in number during ORGANOGENESIS. Somites give rise to SKELETON (sclerotome); MUSCLES (myotome); and DERMIS (dermatome).

A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.

A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.

Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.

A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

The observable response an animal makes to any situation.

A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.

The time from the onset of a stimulus until a response is observed.

Includes both producing and responding to words, either written or spoken.

The common chimpanzee, a species of the genus Pan, family HOMINIDAE. It lives in Africa, primarily in the tropical rainforests. There are a number of recognized subspecies.

Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.

The hollow, muscular organ that maintains the circulation of the blood.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.

Subjectively experienced sensations in the absence of an appropriate stimulus, but which are regarded by the individual as real. They may be of organic origin or associated with MENTAL DISORDERS.

The developmental stage that follows BLASTULA or BLASTOCYST. It is characterized by the morphogenetic cell movements including invagination, ingression, and involution. Gastrulation begins with the formation of the PRIMITIVE STREAK, and ends with the formation of three GERM LAYERS, the body plan of the mature organism.

Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).

Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.

The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.

A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.

The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.

Performance of complex motor acts.

The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.

Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.

The detailed examination of observable activity or behavior associated with the execution or completion of a required function or unit of work.

Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.

Family of the suborder HAPLORHINI (Anthropoidea) comprising bipedal primate MAMMALS. It includes modern man (HOMO SAPIENS) and the great apes: gorillas (GORILLA GORILLA), chimpanzees (PAN PANISCUS and PAN TROGLODYTES), and orangutans (PONGO PYGMAEUS).

Morphological and physiological development of EMBRYOS.

Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.

One of the two types of ACTIVIN RECEPTORS or activin receptor-like kinases (ALK'S). There are several type I activin receptors. The major active ones are ALK-2 (ActR-IA) and ALK-4 (ActR-IB).

The region of the cerebral cortex that receives the auditory radiation from the MEDIAL GENICULATE BODY.

An aquatic genus of the family, Pipidae, occurring in Africa and distinguished by having black horny claws on three inner hind toes.

Elements of limited time intervals, contributing to particular results or situations.

The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.

A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.

An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).

A characteristic symptom complex.

The science and art of collecting, summarizing, and analyzing data that are subject to random variation. The term is also applied to the data themselves and to the summarization of the data.

Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.

Central peptidergic neurons are hyperactive during collateral sprouting and inhibition of activity suppresses sprouting. (1/6942)

Little is known regarding the effect of chronic changes in neuronal activity on the extent of collateral sprouting by identified CNS neurons. We have investigated the relationship between activity and sprouting in oxytocin (OT) and vasopressin (VP) neurons of the hypothalamic magnocellular neurosecretory system (MNS). Uninjured MNS neurons undergo a robust collateral-sprouting response that restores the axon population of the neural lobe (NL) after a lesion of the contralateral MNS (). Simultaneously, lesioned rats develop chronic urinary hyperosmolality indicative of heightened neurosecretory activity. We therefore tested the hypothesis that sprouting MNS neurons are hyperactive by measuring changes in cell and nuclear diameters, OT and VP mRNA pools, and axonal cytochrome oxidase activity (COX). Each of these measures was significantly elevated during the period of most rapid axonal growth between 1 and 4 weeks after the lesion, confirming that both OT and VP neurons are hyperactive while undergoing collateral sprouting. In a second study the hypothesis that chronic inhibition of neuronal activity would interfere with the sprouting response was tested. Chronic hyponatremia (CH) was induced 3 d before the hypothalamic lesion and sustained for 4 weeks to suppress neurosecretory activity. CH abolished the lesion-induced increases in OT and VP mRNA pools and virtually eliminated measurable COX activity in MNS terminals. Counts of the total number of axon profiles in the NL revealed that CH also prevented axonal sprouting from occurring. These results are consistent with the hypothesis that increased neuronal activity is required for denervation-induced collateral sprouting to occur in the MNS. (+info)

Retinotopic mapping of lateral geniculate nucleus in humans using functional magnetic resonance imaging. (2/6942)

Subcortical nuclei in the thalamus, which play an important role in many functions of the human brain, provide challenging targets for functional mapping with neuroimaging techniques because of their small sizes and deep locations. In this study, we explore the capability of high-resolution functional magnetic resonance imaging at 4 Tesla for mapping the retinotopic organization in the lateral geniculate nucleus (LGN). Our results show that the hemifield visual stimulation only activates LGN in the contralateral hemisphere, and the lower-field and upper-field visual stimulations activate the superior and inferior portion of LGN, respectively. These results reveal a similar retinotopic organization between the human and nonhuman primate LGN and between LGN and the primary visual cortex. We conclude that high-resolution functional magnetic resonance imaging is capable of functional mapping of suborganizations in small nuclei together with cortical activation. This will have an impact for studying the thalamocortical networks in the human brain. (+info)

Command-related distribution of regional cerebral blood flow during attempted handgrip. (3/6942)

To localize a central nervous feed-forward mechanism involved in cardiovascular regulation during exercise, brain activation patterns were measured in eight subjects by employing positron emission tomography and oxygen-15-labeled water. Scans were performed at rest and during rhythmic handgrip before and after axillary blockade with bupivacaine. After the blockade, handgrip strength was reduced to 25% (range 0-50%) of control values, whereas handgrip-induced heart rate and blood pressure increases were unaffected (13 +/- 3 beats/min and 12 +/- 5 mmHg, respectively; means +/- SE). Before regional anesthesia, handgrip caused increased activation in the contralateral sensory motor area, the supplementary motor area, and the ipsilateral cerebellum. We found no evidence for changes in the activation pattern due to an interaction between handgrip and regional anesthesia. This was true for both the blocked and unblocked arm. It remains unclear whether the activated areas are responsible for the increase in cardiovascular variables, but neural feedback from the contracting muscles was not necessary for the activation in the mentioned areas during rhythmic handgrip. (+info)

Language processing is strongly left lateralized in both sexes. Evidence from functional MRI. (4/6942)

Functional MRI (fMRI) was used to examine gender effects on brain activation during a language comprehension task. A large number of subjects (50 women and 50 men) was studied to maximize the statistical power to detect subtle differences between the sexes. To estimate the specificity of findings related to sex differences, parallel analyses were performed on two groups of randomly assigned subjects. Men and women showed very similar, strongly left lateralized activation patterns. Voxel-wise tests for group differences in overall activation patterns demonstrated no significant differences between women and men. In further analyses, group differences were examined by region of interest and by hemisphere. No differences were found between the sexes in lateralization of activity in any region of interest or in intrahemispheric cortical activation patterns. These data argue against substantive differences between men and women in the large-scale neural organization of language processes. (+info)

Selective horizontal dysmetropsia following prestriate lesion. (5/6942)

We describe a patient (P.S.) who, following a right prestriate lesion, reported that objects in the left visual field appeared distorted and smaller than those on the right. Other aspects of visual processing were remarkably unaffected. We carried out a series of size comparison tests using simple or complex stimuli and requiring different types of behavioural responses. We found that P.S. significantly underestimated the size of stimuli presented in her left visual field. When comparison tasks involved stimuli placed along the vertical axis or in the right visual field, P.S. performed well. The vertical and horizontal components of size distortion were found to be differentially affected. We conclude that size processing may be dissociated from other aspects of visual processing, such as form or colour processing, and depends critically on part of the occipital, prestriate areas (Brodmann areas 18-19). (+info)

The role of ventral medial wall motor areas in bimanual co-ordination. A combined lesion and activation study. (6/6942)

Two patients with midline tumours and disturbances of bimanual co-ordination as the presenting symptoms were examined. Both reported difficulties whenever the two hands had to act together simultaneously, whereas they had no problems with unimanual dexterity or the use of both hands sequentially. In the first patient the lesion was confined to the cingulate gyrus; in the second it also invaded the corpus callosum and the supplementary motor area. Kinematic analysis of bimanual in-phase and anti-phase movements revealed an impairment of both the temporal adjustment between the hands and the independence of movements between the two hands. A functional imaging study in six volunteers, who performed the same bimanual in-phase and anti-phase tasks, showed strong activations of midline areas including the cingulate and ventral supplementary motor area. The prominent activation of the ventral medial wall motor areas in the volunteers in conjunction with the bimanual co-ordination disorder in the two patients with lesions compromising their function is evidence for their pivotal role in bimanual co-ordination. (+info)

Multicentre European study of thalamic stimulation in parkinsonian and essential tremor. (7/6942)

OBJECTIVES: Thalamic stimulation has been proposed to treat disabling tremor. The aims of this multicentre study were to evaluate the efficacy and the morbidity of thalamic stimulation in a large number of patients with parkinsonian or essential tremor. METHODS: One hundred and eleven patients were included in the study and 110 were implanted either unilaterally or bilaterally. Patients were evaluated with clinical scales, before and up to 12 months after surgery. RESULTS: Upper and lower limb tremor scores were reduced in both groups. Eighty five per cent of the electrodes satisfied the arbitrary criteria of two point reduction in rest tremor reduction in the parkinsonian tremor group and 89% for postural tremor reduction in the essential tremor group. In the parkinsonian tremor group, limb akinesia and limb rigidity scores were moderately but significantly reduced. Axial scores were unchanged. In the essential tremor group, head tremor was significantly reduced only at 3 months and voice tremor was non-significantly reduced. Activities of daily living were improved in both groups. Changes in medication were moderate. Adverse effects related to the surgery were mild and reversible. CONCLUSIONS: Thalamic stimulation was shown to be an effective and relatively safe treatment for disabling tremor. This procedure initially applied in a very limited number of centres has been successfully used in 13 participating centres. (+info)

Cognitive outcome after unilateral pallidal stimulation in Parkinson's disease. (8/6942)

OBJECTIVES: Chronic high frequency electrostimulation of the globus pallidus internus mimics pallidotomy and improves clinical symptoms in Parkinson's disease. The aim of this study was to investigate the cognitive consequences of unilateral deep brain stimulation. METHODS: Twenty non-demented patients with Parkinson's disease (age range 38-70 years) were neuropsychologically assessed 2 months before and 3 months after unilateral pallidal stimulation. The cognitive assessment included measures of memory, spatial behaviour, and executive and psychomotor function. In addition to group analysis of cognitive change, a cognitive impairment index (CII) was calculated for each individual patient representing the percentage of cognitive measures that fell more than 1 SD below the mean of a corresponding normative sample. RESULTS: Neurological assessment with the Hoehn and Yahr scale and the unified Parkinson's disease rating scale disclosed a significant postoperative reduction in average clinical Parkinson's disease symptomatology (p<0.001). Repeated measures multivariate analysis of variance (using right/left side of stimulation as a between subjects factor) showed no significant postoperative change in cognitive performance for the total patient group (main effect of operation). The side of stimulation did not show a significant differential effect on cognitive performance (main effect of lateralisation). There was no significant operation by lateralisation interaction effect. Although the patients experienced significant motor symptom relief after pallidal stimulation, they remained mildly depressed after surgery. Analysis of the individual CII changes showed a postoperative cognitive decline in 30% of the patients. These patients were significantly older and took higher preoperative doses of levodopa than patients showing no change or a postoperative cognitive improvement. CONCLUSIONS: Left or right pallidal stimulation for the relief of motor symptoms in Parkinson's disease seems relatively safe, although older patients and patients needing high preoperative doses of levodopa seem to be more vulnerable for cognitive decline after deep brain stimulation. (+info)

Gur RE, Chin S (1999). "Laterality in functional brain imaging studies of schizophrenia". Schizophrenia Bulletin. 25 (1): 141- ... Similarly, there is now evidence to suggest there may be a number of functional and structural anomalies in the brains of some ... Some functional neuroimaging studies have also shown that, after taking amphetamine, patients diagnosed with schizophrenia show ... Arinami T, Gao M, Hamaguchi H, Toru M (April 1997). "A functional polymorphism in the promoter region of the dopamine D2 ...

https://en.wikipedia.org/wiki/Dopamine_hypothesis_of_schizophrenia

Conditions include leftward functional hemispheric lateralization, loss of laterality for language comprehension, a reduction ... Split-brain Laterality Lateralization of brain function Alien hand syndrome Michael Gazzaniga Roger Wolcott Sperry Nielsen, J. ... Studies have found that individuals with schizophrenia have a lack in brain asymmetry thus reducing the functional efficiency ... right-brain hypothesis with resting state functional connectivity magnetic resonance imaging. PLOS ONE, 8(8), e71275. LeMay M ( ...

https://en.wikipedia.org/wiki/Brain_asymmetry

The teeth of plankton-feeders such as the basking shark are small and non-functional. Cartilaginous jaws and their teeth Jaw ... development and a genetic locus for jaw laterality in Lake Tanganyika scale-eating cichlids". BMC Biology. 8 (1): 8. doi: ... Mehta, R. S.; Wainwright, P. C. (2008). "Functional morphology of the pharyngeal jaw apparatus in moray eels" (PDF). Journal of ... Wainwright, P. C. (2006). "Functional Morphology of the Pharyngeal Jaw Apparatus". In Shadwick, R. E.; Lauder, G. V. (eds.). ...

https://en.wikipedia.org/wiki/Fish_jaw

Janovetz, Jeff (2005). "Functional morphology of feeding in the scale-eating specialist Catoprion mento" (PDF). The Journal of ... development and a genetic locus for jaw laterality in Lake Tanganyika scale-eating cichlids". BMC Biology. 8 (1): 8. doi: ... Stewart, T. A.; Albertson, R. C. (2010). "Evolution of a unique predatory feeding apparatus: functional anatomy, ...

https://en.wikipedia.org/wiki/Fish_scale

... functional anatomy, development and a genetic locus for jaw laterality in Lake Tanganyika scale-eating cichlids". BMC Biology. ...

https://en.wikipedia.org/wiki/Lake_Tanganyika

Stewart, T. A.; Albertson, R. C. (2010). "Evolution of a unique predatory feeding apparatus: functional anatomy, development ... and a genetic locus for jaw laterality in Lake Tanganyika scale-eating cichlids". BMC Biology. 8 (1): 8. doi:10.1186/1741-7007- ...

https://en.wikipedia.org/wiki/List_of_animals_featuring_external_asymmetry

... and Roger Wolcott Sperry in the 1960s on split-brain patients led to an even greater understanding of functional laterality. ... Because of this functional division of the left and right sides of the body and of the space that surrounds it, the processing ... Furthermore, the functional map of the motor and sensory cortices is fairly consistent from person to person; Penfield and ... Lucas, Timothy (2004). "Functional separation of languages in the bilingual brain: a comparison of electrical stimulation ...

https://en.wikipedia.org/wiki/Lateralization_of_brain_function

Mazzarello, Paolo (2011). "Cesare Lombroso: an anthropologist between evolution and degeneration". Functional Neurology. 26 (2 ... Laterality: Asymmetries of Body, Brain and Cognition. 18 (4): 416-436. doi:10.1080/1357650x.2012.697171. PMID 22757625. S2CID ... Laterality. 18 (4): 416-436. doi:10.1080/1357650X.2012.697171. PMID 22757625. S2CID 30990112. Bailey, Frankie Y. (Winter 2005 ...

https://en.wikipedia.org/wiki/Cesare_Lombroso

2002). "Sex differences in functional brain activation during a lexical visual field task". Brain and Language. 80 (1): 97-105 ... 2006). "Sex differences in cerebral laterality of language and visuospatial processing". Brain and Language. 98 (2): 150-158. ... 1995). "Sex differences in the functional organization of the brain for language". Nature. 373 (6515): 607-609. doi:10.1038/ ... 2003). "Sex differences in semantic language processing: A functional MRI study". Brain and Language. 84 (2): 264-272. doi: ...

https://en.wikipedia.org/wiki/Father_Tongue_hypothesis

The unusual functional laterality in speech production (e.g. right hemisphere auditory processing) found in some individuals ...

https://en.wikipedia.org/wiki/Risk_factors_of_schizophrenia

... reflecting a significant sex difference in the magnitude of laterality effects, with men obtaining larger laterality effects ... Kimura, Doreen (1967). "Functional Asymmetry of the Brain in Dichotic Listening". Cortex. 3 (2): 163-178. doi:10.1016/S0010- ... In order to obtain results, a Functional magnetic resonance imaging (fMRI) was used by Jancke et al (2001) to determine the ... In 1994, M.F. Green and colleagues tried to relate "the functional integration of the left hemisphere in hallucinating and ...

https://en.wikipedia.org/wiki/Dichotic_listening

While developed for functional status evaluation, the HCS prototype ultimately led to the discovery of the brain vital signs ... March 15, 2012). "Spatial MEG Laterality maps for language: Clinical applications in epilepsy." Human Brain Mapping. Vol. 34:8 ... Gawryluk JR, Mazerolle EL and D'Arcy RCN (August 8, 2014) "Does functional MRI detect activation in white matter? A review of ... Gawryluk, Jodie R.; Mazerolle, Erin L.; Beyea, Steven D.; D'Arcy, Ryan C. N. (2014-08-04). "Functional MRI activation in white ...

https://en.wikipedia.org/wiki/Ryan_D'Arcy

Functional and structural differences between left and right brain hemispheres can be found in many other vertebrates and also ... This has been called the "laterality-valence hypothesis". One sub-set of laterality in animals is limb dominance. Preferential ... testing for laterality can be a useful predictor of a successful guide dog. Knowing a guide dog's laterality can also be useful ... causing strains to differ in the degree of laterality of its individuals. Long-term memory of previously gained laterality in ...

https://en.wikipedia.org/wiki/Laterality

After capturing a set of baseline images, some labs further require the patient to undergo cold-water autonomic-functional- ... laterality reconstruction, (b) motor imagery, and (c) mirror therapy. Transcutaneous Electrical Nerve Stimulation (TENS) ... Evidence supports its use in treating pain and edema associated with CRPS although it doesn't seem to increase functional ... a functional MRI study". Pain. 114 (1-2): 93-103. doi:10.1016/j.pain.2004.12.001. PMID 15733635. S2CID 19187294. DR WILL HOWARD ...

https://en.wikipedia.org/wiki/Complex_regional_pain_syndrome

Functional neuroimaging methods such as PET and fMRI are used to study the complex neural mechanisms of the human language ... Most neuroimaging studies show no laterality differences between monolingual and bilingual speakers, supporting the hypothesis ... Using functional magnetic resonance imaging (fMRI), representations of L1 and L2 have been found in spatially isolated parts of ... Functional imaging methods have revealed that holding proficiency constant leads to age of acquisition not having a large ...

https://en.wikipedia.org/wiki/Neuroscience_of_multilingualism

doi:10.2190/em.27.1.f. Xenakis, Ioannis; Arnellos, Argyris; Darzentas, John (1 August 2012). "The functional role of emotions ... Powell, W. Ryan; Schirillo, James A. (1 August 2011). "Hemispheric laterality measured in Rembrandt's portraits using pupil ...

https://en.wikipedia.org/wiki/Art_and_emotion

Chicago: Nelson-Hall (1983) Human Laterality, Academic Press (1984) The Lopsided Ape: Evolution of the Generative Mind, Oxford ... doi:10.1016/j.neuropsychologia.2008.10.016 Milivojevic, B., Hamm, J. P., & Corballis, M. C. (2009). "Functional neuroanatomy of ...

https://en.wikipedia.org/wiki/Michael_Corballis

Laterality, 11, 373-393. Jeffery, G. (2001). Architecture of the optic chiasm and the mechanisms that sculpt its development. ... A critical assumption has been that differences in performance with lateralized stimuli nearly always reflect functional ... Banich, M.T. (2003). The divided visual field technique in laterality and interhemispheric integration. In K. Hughdahl (Ed.), ... if a cerebral hemisphere has functional advantages with some aspect of a particular task, an experimenter might observe ...

https://en.wikipedia.org/wiki/Divided_visual_field_paradigm

The valence-specific laterality effect in free viewing conditions: The influence of sex, handedness, and response bias. Brain ... Functional asymmetry of emotions in primates: new findings in chimpanzees. Brain Research Bulletin. 57: 561-564, 2002. Vytal, K ... Below are a few regions and structure involved in emotional processing that show functional lateralization. Using a PET scan, ... The vast majority of the data comes from functional imaging, skin conductance response (SCR), standardized tests ranging from ...

https://en.wikipedia.org/wiki/Emotional_lateralization

Anatomo-functional study of the temporo-parieto-occipital region: dissection, tractographic and brain mapping evidence from a ... A Quantitative Tractography Study Into the Connectivity, Segmentation and Laterality of the Human Inferior Longitudinal ... Proc Natl Acad Sci U S A. Feb 4;111(5):1981-6. doi: 10.1073/pnas.1324037111 Herbet G, Zemmoura I, Duffau H. Functional Anatomy ... Based on these recent findings ILF can be described as a multi-functional white matter pathway involved in visually guided ...

https://en.wikipedia.org/wiki/Inferior_longitudinal_fasciculus

Sergent, J (1992). "Functional neuroanatomy of face and object processing : A positron emission tomography study". Brain. 115 ( ... Sergent, J. (1987). Information processing and laterality effects for object and face perception. In G. W. Humphreys, & M. J. ... Justine Sergent was one of the first researchers that brought forth evidence towards the functional neuroanatomy of face ... Sergent, J., MacDonald, B., Zuck, E. (1994). Structural and functional organization of knowledge about faces and proper names ...

https://en.wikipedia.org/wiki/Justine_Sergent

Functional approaches rely on understanding what roles emotions play in humans and examining that role in animals. A widely ... Barnard, S., Matthews, L., Messori, S., Podaliri-Vulpiani, M. and Ferri, N. (2015). "Laterality as an indicator of emotional ... Mendl, M., Burman, O.H.P. and Paul, E.S. (2010). "An integrative and functional framework for the study of animal emotion and ... Dawkins suggests that merely mechanistic or functional research will provide the answer on its own, but suggests that a mixture ...

https://en.wikipedia.org/wiki/Emotion_in_animals

Incidence and laterality". J AAPOS. 11 (4): 367-372. doi:10.1016/j.jaapos.2007.02.017. PMID 17588790. Huang MH, Gruss JS, ... but also the functional aspect. This is especially prevalent with asymmetric conditions, such as unilateral coronal synostosis ... "Long-term functional outcome in 167 patients with syndromic craniosynostosis; defining a syndrome-specific risk profile". ...

https://en.wikipedia.org/wiki/Craniosynostosis

a b c d e f g Ruppert, E. E., Fox, R. S. and Barnes, R. D. Invertebrate Zoology: A Functional Evolutionary Approach. Thomson, ... Laterality. *Proper right and proper left - terms for unambiguous directions, like port and starboard ... Some species (mainly troglobites) have no functional eyes at all. In what is seen as the likeliest ancestral arrangement of the ...

https://en.m.wikipedia.org/wiki/Dorsal_side

In: Human Laterality, Davidson RH, Hugdahl K, eds. Cambridge, MA: MIT Press, pp. 491-532 Nebes RD, ed. (1990): The ... There is little functional plasticity observed in partial and complete callosotomies; however, much more plasticity can be seen ... There is little functional plasticity observed in partial and complete callosotomies on adults, the most neuroplasticity is ... Funnell M. G.; Corballis P. M.; Gazzaniga M. S. (2000). "Insights into the functional specificity of the human corpus callosum ...

https://en.wikipedia.org/wiki/Split-brain

Some species (mainly troglobites) have no functional eyes at all. In what is seen as the likeliest ancestral arrangement of the ... Laterality - Preference most humans show for one side of their body over the other ... Ruppert, EE; Fox, RS; Barnes, RD (2004). Invertebrate zoology : a functional evolutionary approach (7th ed.). Thomson, Belmont ...

https://en.wikipedia.org/wiki/Ventral

Kim J, Ahn S, Ren XR, Whalen EJ, Reiter E, Wei H, Lefkowitz RJ (2005). "Functional antagonism of different G protein-coupled ... a series of developmental defects arising from improper left-right laterality during organogenesis. Overexpression of GRK5 in ... also called functional selectivity), where a drug binding to a receptor may bias that receptor's signaling toward a particular ...

https://en.wikipedia.org/wiki/GRK5

Other critical functional parts are the N-terminal Cobl Homology domain, which can also be found in the ancestor of Cobl, Cobl- ... Zebra fish deficient for Cobl showed severe defects in body laterality and balance keeping. Several actin nucleators are ... An important functional part of this actin-nucleating protein is the C-terminus, which contains 3 Wiskott-Aldrich syndrome ... Cobl was then cloned fully and its neuronal functions were characterized in primary neuronal cultures in functional slices of ...

https://en.wikipedia.org/wiki/Cordon-bleu_protein

Incidence and laterality". J AAPOS. 11 (4): 367-372. doi:10.1016/j.jaapos.2007.02.017. PMID 17588790.. ... but also the functional aspect.[42] This is especially prevalent with asymmetric conditions, such as unilateral coronal ... "Long-term functional outcome in 167 patients with syndromic craniosynostosis; defining a syndrome-specific risk profile". ...

https://en.m.wikipedia.org/wiki/Craniosynostosis

Boso M, Politi P, Barale F, Enzo E (2006). "Neurophysiology and neurobiology of the musical experience". Functional Neurology. ... laterality and directional.[34][self-published source?] Music can both motivate and provide a sense of distraction.[33] ... prolonged and marked functional impairment; and 6) hallucinatory experiences other than thinking that he or she hears the voice ...

https://en.m.wikipedia.org/wiki/Neurologic_music_therapy

Ruppert, EE; Fox, RS; Barnes, RD (2004). Invertebrate zoology : a functional evolutionary approach (7th ed.). Thomson, Belmont ... Laterality - Preference most humans show for one side of their body over the other ...

https://en.wikipedia.org/wiki/Dorsum_

Obeso JA, Rodríguez-Oroz MC, Benitez-Temino B, Blesa FJ, Guridi J, Marin C, Rodriguez M (2008). "Functional organization of the ... "A preliminary investigation of laterality in Parkinson's disease and susceptibility to psychosis". Journal of Neurology, ... physiotherapists have a variety of strategies to improve functional mobility and safety. Areas of interest with respect to gait ...

https://en.wikipedia.org/?title=Parkinson's_disease

Rarely, left atrial isomeric patients have a single, normal, functional spleen. Patients lacking a functional spleen are in ... Heterotaxy in general refers to any defect of left-right laterality and arrangement of the visceral organs. This does not ... Functionally asplenic patients have an elevated lifetime risk of septicemia, as they have no functional spleen for fighting ... Left-atrial isomeric patients have less severe complications, as they typically have 2 functional ventricles. In this case, ...

https://en.wikipedia.org/wiki/Situs_ambiguus

This immunisation is not functional against a different tumour. It was used in autologous manner in clinical studies for gp96 ... Along with hspb7, hspb12 is involved in cardiac laterality determination.[9] A kinase of the nitric oxide cell signalling ... "Functional significance of hsp90 complexes with NOS and sGC in endothelial cells". Clinical Hemorheology and Microcirculation ... "Small heat shock proteins are necessary for heart migration and laterality determination in zebrafish". Developmental Biology ...

https://en.wikipedia.org/wiki/Heat_shock_protein

... and functional dyspepsia.[50] Alexithymia is further linked with disorders such as migraine headaches, lower back pain, ... "Laterality of expression in portraiture: putting your best cheek forward". Proceedings of the Royal Society of London B: ... "Alexithymia and somatosensory amplification in functional dyspepsia". Psychosomatics. 45 (6): 508-16. doi:10.1176/appi.psy. ...

https://en.m.wikipedia.org/wiki/Alexithymia

"Laterality. 12 (1): 31-49. doi:10.1080/13576500600886796. PMID 17090448.. *^ Gauthier I, Skudlarski P, Gore JC, Anderson AW; ... using a novel functional transcranial Doppler (fTCD) technique called functional transcranial Doppler spectroscopy (fTCDS), ... Smith WM (July 2000). "Hemispheric and facial asymmetry: gender differences". Laterality. 5 (3): 251-8. doi:10.1080/713754376. ... Data from magnetic resonance imaging and functional magnetic resonance imaging has shown that a smaller volume of the fusiform ...

https://en.m.wikipedia.org/wiki/Face_perception

Functional transcranial Doppler (fTCD)[edit]. Functional transcranial Doppler sonography (fTCD) is a neuroimaging tool for ... Laterality. 12 (1): 31-49. doi:10.1080/13576500600886796. PMID 17090448.. *^ Meinders, JM; Kornet, L; Brands, PJ; Hoeks, AP ( ... Functional transcranial Doppler spectroscopy (fTCDS)[edit]. This section may require cleanup to meet Wikipedia's quality ... The method was first described by Philip Njemanze in 2007, and was referred to as functional transcranial Doppler spectroscopy ...

https://en.wikipedia.org/wiki/Transcranial_doppler

a b c d e f g Ruppert, E. E., Fox, R. S. and Barnes, R. D. Invertebrate Zoology: A Functional Evolutionary Approach. Thomson, ... Some species (mainly troglobites) have no functional eyes at all. In what is seen as the likeliest ancestral arrangement of the ... Laterality. * Proper right and proper left. * Reflection symmetry. * Sinistral and dextral. * Direction (disambiguation) ...

https://en.m.wikipedia.org/wiki/Dorsum_

FunctionalEdit. Functional approaches rely on understanding what roles emotions play in humans and examining that role in ... This has been called the "laterality-valence hypothesis".[12]. Basic and complex human emotionsEdit. In humans, a distinction ... LateralityEdit. It has been proposed that negative, withdrawal-associated emotions are processed predominantly by the right ... A widely used framework for viewing emotions in a functional context is that described by Oatley and Jenkins[22] who see ...

https://en.m.wikipedia.org/wiki/Emotion_in_animals

Both the right and left hemispheres generate an N1, but the laterality of the N1 depends on whether a stimulus is presented ... Functional dissociation of P1 and N1 components. Electroencephalography & Clinical Neurophysiology, 75(6): 528-542. Callaway, E ...

https://en.wikipedia.org/wiki/Visual_N1

Cuvier's insistence on the functional integration of organisms led him to classify animals into four "branches," or ... Glossary of plant morphology Glossary of leaf morphology Glossary of entomology terms Plant morphology Handedness Laterality ... Cuvier's insistence on the functional integration of organisms led him to classify animals into four "branches," or ...

https://en.wikipedia.org/wiki/Symmetry_in_biology

Komisaruk, B., & Whipple, B.; Whipple (2005). "Functional MRI of the brain during orgasm in women". Annual Review of Sex ... Cohen, Harvey D.; Rosen, Raymond C.; Goldstein, Leonide (May 1976). "Electroencephalographic laterality changes during human ... Before Komisaruk et al.'s functional magnetic resonance (fMRI) research on nipple stimulation in 2011, reports of women ... when several women stimulated themselves in a functional magnetic resonance (fMRI) machine. "I think that the bulk of the ...

https://en.wikipedia.org/wiki/Orgasm

The laterality of the sensory inputs makes a difference insofar as left-sided inputs directed to the intact left hemisphere are ... Different degrees of multisensory integration may occur depending upon the functional relevance of a given modality. Altogether ... Jan 1982). "Failure to obtain functional equivalence between dopamine receptor blockade and extinction: evidence supporting a ...

https://en.wikipedia.org/wiki/Extinction_(neurology)

... and cerebral laterality". Journal of Experimental Psychology: Learning, Memory, and Cognition. 9 (3): 544-555. doi:10.1037/0278 ... impair cognitive functions but leave emotional responses fully functional. The mere-exposure effect posits that repeated ...

https://en.wikipedia.org/wiki/Mere-exposure_effect

ISBN 978-81-7141-746-9. William O. Reece (2009). Functional Anatomy and Physiology of Domestic Animals. John Wiley & Sons. ISBN ... Laterality. 15 (5): 514-534. doi:10.1080/13576500903049324. PMID 19629847. S2CID 13283847. Proctor, Helen S.; Carder, Gemma (9 ...

https://en.wikipedia.org/wiki/Cattle

Craniofacial laterality in the scale-eating specialist Perissodus microlepis was found to be evident early in development and ... Continued work on the developmental genetic basis of laterality in the Perissodini will facilitate a better understanding of ... Here we examine the evolution and development of craniofacial morphology and laterality among Lake Tanganyika scale-eating ... we show that the evolutionary history of the Perissodini is characterized by an accentuation of craniofacial laterality such ...

https://bmcbiol.biomedcentral.com/articles/10.1186/1741-7007-8-8

Functional laterality refers to a natural asymmetry in left or right-side dominance, for example in terms of handedness... ... What is functional laterality? Functional laterality refers to a natural asymmetry in left or right-side dominance, for example ... What is the evidence for altered functional laterality?. High quality evidence shows that people with schizophrenia are more ... as well as altered visual and auditory dominance that may reflect abnormalities in brain laterality and dominance. ...

https://library.neura.edu.au/schizophrenia/signs-and-symptoms/general-signs-and-symptoms/functional-laterality/

What is functional laterality? Functional laterality refers to a natural asymmetry in left or right-side dominance, for example ... What is the evidence for altered functional laterality?. High quality evidence shows that people with schizophrenia are more ... as well as altered visual and auditory dominance that may reflect abnormalities in brain laterality and dominance. ...

https://library.neura.edu.au/browse-library/signs-and-symptoms/functional-laterality/

... positive results that are progressively retained over time specific to patient-centered outcome measures as well as functional ... Laterality of Motor Control and Induced Gamma-Band Activity During Voluntary Movement: A Clinical Perspective of an Inexpensive ... 428" contains a laterality-indexed item not sufficiently emphasized by the authors. Using electroencephalography and ...

https://journals.humankinetics.com/search?page=7&pageSize=10&q=%22laterality%22&sort=relevance

Comparative and Functional Genomics. Volume 2 (2001), Issue 2, Pages 60-68. http://dx.doi.org/10.1002/cfg.74. Research Article ... Genetic Steps to Organ Laterality in Zebrafish. Jau-Nian Chen,1,2 Frauke van Bebber,3 Allan M. Goldstein,1,2 Fabrizio C. ... That laterality decisions of organs may be independently perturbed, as in the Class 3 mutation, indicates that there are ... We find that the mutations can be classified on the basis of whether they perturb relationships among organ laterality. In ...

https://www.hindawi.com/journals/ijg/2001/621835/abs/

... Neurosci Res. 2009 Jun;64(2):240-2. doi: 10.1016/j.neures ... Functional Laterality* * Male * Mice * Neocortex / physiology* * Neurons / physiology * Occipital Lobe / physiology * Parietal ...

https://pubmed.ncbi.nlm.nih.gov/19428706/?holding=f1000

Brain laterality in schizophrenia has been examined through the application of functional neuroimaging methods. These methods ... Brain laterality in schizophrenia has been examined through the application of functional neuroimaging methods. These methods ... Recent advances in basic and clinical neuroscience provide an opportunity for focused application of functional imaging in ... and functional magnetic resonance imaging for measuring changes attributable to CBF. This article highlights the application of ...

http://oxfordindex.oup.com/view/10.1093/oxfordjournals.schbul.a033361

Effect of voicing on perceptual auditory laterality in Estonian and Norwegian native speakers - Volume 39 Issue 2 - RENÉ ... Van der Haegen, L., Westerhausen, R., Hugdahl, K., & Brysbaert, M. (2013). Speech dominance is a better predictor of functional ... Laterality, 20, 434-452. Brancucci, A., Penna, S. D., Babiloni, C., Vecchio, F., Capotosto, P., Rossi, D., Rossini, . . ., P., ... Laterality, 15, 343-360. Asu, E. L., & Teras, P. (2009). Estonian. Journal of the International Phonetic Association, 39, 367- ...

https://www.cambridge.org/core/journals/applied-psycholinguistics/article/effect-of-voicing-on-perceptual-auditory-laterality-in-estonian-and-norwegian-native-speakers/E1A59C90CA83AA269EE4846464A146E9

... laterality defects including heart malformations, infertility and hydrocephalus. Using linkage analysis and whole exome ... Homozygous Loss-Of-Function Mutations in MNS1 Cause Laterality Defects and Likely Male Infertility PLoS Genet. 2018 Aug 27;14(8 ... Consistent with the laterality defects observed in these individuals, we found Mns1 to be expressed in mouse embryonic ventral ... Overall, we demonstrate that MNS1 deficiency in humans causes laterality defects (situs inversus) and likely male infertility ...

https://pubmed.ncbi.nlm.nih.gov/30148830/

At a functional level, the medial prefrontal cortex is involved in multiple processes relevant to emotion regulation, including ... Functional Neuroimaging. Negative Emotion Induction Manipulation Check. To assess if the combat images elicited a neural ... New, A. S., Fan, J., Murrough, J. W., Liu, X., Liebman, R. E., Guise, K. G., … Charney, D. S. (2009). A functional magnetic ... Functional MRI Statistical Analysis. The fMRI data were analyzed using SPM8 software (Wellcome Department of Cognitive ...

https://link.springer.com/article/10.1007%2Fs10608-018-9905-x

Auditory scene analysis; Event-related brain potentials (ERPs); Hemispheric laterality; Neural compensation; Reverse hierarchy ... Functional changes in inter- and intra-hemispheric cortical processing underlying degraded speech perception.. Bidelman GM1, ... and show a shift in the functional lateralization of cerebral processing from left to right hemisphere. Increased right ... Our findings demonstrate changes in the functional asymmetry of cortical speech processing during adverse acoustic conditions ...

https://www.ncbi.nlm.nih.gov/pubmed/26386346

The laterality patterns of functional asymmetries were found to be consistent and independent of the conventional upper and ... Even though laterality was confirmed in both grip and elbow flexion, gender difference is more marked in hand grip. ... This study aimed to compare the laterality, and its gender difference, of hand grip and elbow flexion power according to load ... Laterality of Hand Grip and Elbow Flexion Power in Right Hand-Dominant Individuals ...

https://journals.humankinetics.com/search?page=4&pageSize=10&q=%22laterality%22&sort=relevance

Effects of Lesion Location and Laterality. No significant differences were found in the patterns of activation between patients ... Subjects had to score 3 or above on the Functional Ambulatory Capacity rating scale.19 Their mean (SD) Functional Ambulatory ... Functional MRI Correlates of Lower Limb Function in Stroke Victims With Gait Impairment. Christian Enzinger, Heidi Johansen- ... Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET. J Neurosci. 1992; 12: ...

http://stroke.ahajournals.org/content/39/5/1507

Functional laterality‎ (20 Ф). H. *. ► Hippocampus (anatomy)‎ (11 К, 1 С, 74 Ф) ...

https://commons.wikimedia.org/wiki/Category:Brain?uselang=ru

... which explores the functional relationships between hormones and the brain, have indicated that the release of testicular ( ... Voyer, D. (1996). On the magnitude of laterality effects and sex differences in functional literalities. Laterality 1, 51-83. ... In research conducted in the 1990s, sex differences in humans have also been found for functional asymmetry (Voyer, 1996), ... Findings in the field of neuroendocrinology, which explores the functional relationships between hormones and the brain, have ...

https://www.encyclopedia.com/psychology/encyclopedias-almanacs-transcripts-and-maps/sex-differences-learning

Bryden, M. (1982). Laterality: Functional asymmetry in the intact brain. New York: Academic Press.Google Scholar ... Goff, E., Allison, T. & Vaughan, H. (1978). The functional neuroanatomy of event related potentials. In E. Callaway, E. Teuting ...

https://link.springer.com/chapter/10.1007/978-1-4684-7899-0_11

... the Example of Auditory Laterality - Polish Psychological Bulletin ... Brain Functional Asymmetry of Chimpanzees (Pan troglodytes): the Example of Auditory Laterality Journal title. Polish ... Brain Functional Asymmetry of Chimpanzees (Pan troglodytes): the Example of Auditory Laterality. Justyna Szymańska; Maciej ... Cantalupo (2001), Asymmetric Broca s area in great apes, Nature, 414. ; Rogers (1989), Laterality in animals, The International ...

http://journals.pan.pl/dlibra/publication/116310/edition/101077/content/brain-functional-asymmetry-of-chimpanzees-pan-troglodytes-the-example-of-auditory-laterality-justyna-szymanska-maciej-trojan-anna-jakucinska-katarzyna-wejchert-maciej-kapusta-julia-sikorska?language=en

In this work, we report two patients with a DAND5 heterozygous non-synonymous variant (c.455G , A) in the functional domain of ... A Nodal-dependent luciferase assay was conducted in order to determine the functional effect of the variant found. ... Altogether, our results provide new insight into the molecular mechanism of the laterality defects and related CHDs, priming ... The functional analysis assay showed a significant decrease in the activity of this variant protein when compared to its wild- ...

https://bmcmedgenet.biomedcentral.com/articles/10.1186/s12881-017-0444-1

Laterality and neuropsychiatric disorders: Schizophrenia and the left hemisphere.. *Laterality and differential functional ... Course 3: Laterality and Functional Organization of the Brain. Topics covered:. *Where the traditional notions of hemispheric ... Laterality and learning disabilities (dyslexias vs NVLD).. *Laterality and dementias: Is fronto-temporal dementia lateralized? ... Laterality and Brain Dysfunction Ended $95.00 $0.00 Combined ticket for any two courses (please click on Order Now and scroll ...

https://www.eventbrite.com/e/video-courses-the-human-brain-and-brain-disorders-tickets-16826196607

Functional cerebral asymmetry in auditory motion perception. Laterality, 12, 87-99.. Book sections:. *Hugdahl, K. & Hirnstein, ... Ocklenburg, S., Güntürkün, O., Hugdahl, K. & Hirnstein, M. (2015). Laterality and mental disorders in the postgenomic age - A ... Ocklenburg, Sebastian; Güntürkün, Onur; Hugdahl, Kenneth; Hirnstein, Marco. 2015. Laterality and mental disorders in the ... The evolutionary origins of functional cerebral asymmetries in humans: Does lateralization enhance parallel processing? ...

http://www.uib.no/user/11032

Both headache laterality and headache type interact with the degree of co-morbidity with higher impairment in patients with ... Both headache laterality and headache type interact with the degree of co-morbidity with higher impairment in patients with ... Here we aimed to investigate the influence of co-morbid headache type and headache laterality on tinnitus characteristics. ... Based on these data patients were categorized according to headache type and headache laterality and their clinical ...

https://www.frontiersin.org/articles/10.3389/fneur.2017.00440/full

Laterality: Functional Asymmetry In The Intact Brain. New York: Appleton Century.Carr, M. 1983. Sidelights on Xin Heart, Mind ... And thiscan be studied in laterality differences today. What I have tried to present to you is a long and complicated story. It ... The space of consciousness, which I shallhereafter call mind-space, is a functional space that has no location except as we ... and has only an arbitrary and functional location. As a prel-ude to what I am to say later, I wish you to consider that there ...

https://www.slideshare.net/lorebrarian/jaynes-consciousness-voicesmind

Here, we propose a new hypothesis that binary opposition in functional incompatibility applies selection pressure on the ... Here, we propose a new hypothesis that binary opposition in functional incompatibility applies selection pressure on the ... 2003). Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality. Neuron 39, 423-438. doi: ... Brain asymmetry and functional lateralization are recognized in many vertebrates. It is well-known that the left side of the ...

https://www.frontiersin.org/articles/10.3389/fnins.2016.00595/full

Functional Laterality. Humans. Migraine Disorders / complications*, physiopathology, radiography. Occipital Lobe / blood supply ...

http://www.biomedsearch.com/nih/Bilateral-occipital-lobe-infarction-in/1526769.html

Functional Laterality. Head Movements / physiology*. Models, Biological. Physical Stimulation / methods. Probability. Rats. ... Next Document: Probability-based prediction of activity in multiple arm muscles: implications for functional electr.... ...

http://www.biomedsearch.com/nih/Variability-in-velocity-profiles-during/18436634.html

functional connectivity. HC. hippocampus. LI. laterality index. MTS. mesiotemporal sclerosis. nl-TLE. nonlesional TLE. TLE. ... RESULTS: Laterality indices based on fMRI activation maps failed to discriminate among patient groups. Functional connectivity ... Task-based activation maps (laterality indices) and functional connectivity analysis (global and connectivity strengths between ... We hypothesized that different epileptogenic lesions are related to distinct alterations in the functional language connectome ...

http://www.ajnr.org/content/41/1/147

V. Emotional Laterality. PDF (95.2 KB). *14. The Functional Neuroimaging of Human Emotion: Asymmetric Contributions of Cortical ... visual laterality, auditory laterality, emotional laterality, neurological disorders, and psychiatric disorders. ... Functional Magnetic Resonance Imaging. Hemispheric Specialization. Hippocampus. Limbic System. Magnetic Resonance Imaging. ... Going beyond the authors previous book, Brain Asymmetry, this book reflects the most recent thinking on functional asymmetries ...

http://cognet.mit.edu/book/asymmetrical-brain

... and laterality differences (Schneider et al., 2000; Cahill et al., 2001; Canli et al., 2002) compared with men, likely ... coplanar to the functional images for anatomic localization. Finally, a series of functional scans were acquired, using an ... Three sets of functional scans were acquired. Functional images were visually examined in Statistical Parametric Mapping (SPM) ... These blocks were repeated four times during each 6 min functional scan. Three functional scans were taken, resulting in 12 ...

http://www.jneurosci.org/content/25/40/9309

Seghier M (2008) Laterality index in functional MRI: methodological issues. Magn Reson Imaging 26:594-601. doi: 10.1016/j.mri. ... Laterality 18:1-31. doi: 10.1080/1357650X.2011.626561 CrossRefPubMedGoogle Scholar ... 2, 3, 4, 6, 7) may underpin this proposed functional lateralization of frequency processing and the lateralized production of ... Future DTI and functional MRI (fMRI) studies of T. truncatus and other cetaceans are needed to characterize cerebral white ...

https://link.springer.com/article/10.1007/s00429-017-1525-9

Laterality of motor control and consciousness shares the same hemisphere. [Anesthesiology. 2013] ... Regional association of thalamocortical functional connectivity with changes of the state of consciousness. Indices IA and IB ... Functional connectivity was determined as the temporal correlation of blood oxygen level-dependent signals with seed regions ... Regional distributions of specific (A) and nonspecific (B) thalamocortical functional connectivity as measured by voxel count ...

https://www.ncbi.nlm.nih.gov/pubmed/23221862?dopt=Abstract

Functional laterality refers to a natural asymmetry in left or right-side dominance, for example in terms of handedness, or brain function. (edu.au)
Our findings demonstrate changes in the functional asymmetry of cortical speech processing during adverse acoustic conditions and suggest that "cocktail party" listening skills depend on the quality of speech representations in the left cerebral hemisphere rather than compensatory recruitment of right hemisphere mechanisms. (nih.gov)
Laterality: Functional asymmetry in the intact brain. (springer.com)
Here, we propose a new hypothesis that binary opposition in functional incompatibility applies selection pressure on the habenular circuit and leads to asymmetry. (frontiersin.org)
Brain asymmetry and functional lateralization are recognized in many vertebrates. (frontiersin.org)
This study represents the first examination of cetacean white matter asymmetry and constitutes an important step toward understanding potential drivers of structural asymmetry and its role in underpinning functional and behavioral lateralization in cetaceans. (springer.com)
Going beyond the authors' previous book, Brain Asymmetry , this book reflects the most recent thinking on functional asymmetries and their structural correlates in brain anatomy. (mit.edu)
Hypnotizability, laterality of eye movements and functional brain asymmetry. (thenakedscientists.com)
Several vertebrates, including fish, exhibit behavioural laterality and associated morphological asymmetry. (biologists.org)
We also compared the behavioural laterality and mouth asymmetry of G. mento and P. microlepis . (biologists.org)
Using this technique he investigated amongst others functional reorganization after stroke in motor and visual cortex, resting state activity in visual cortex, and topological asymmetry between the hemispheres. (umcutrecht.nl)
Functional left/right asymmetry ("laterality") is a fundamental feature of many nervous systems, but only very few molecular correlates to functional laterality are known. (genetics.org)
and auditory laterality and speech perception, memory, and asymmetry in the context of developmental, neurological, and psychiatric disorders. (mit.edu)
Failure to establish normal left-right (L-R) asymmetry often results in cardiovascular malformations and other laterality defects of visceral organs. (ahajournals.org)
Laterality defects refer to a broad group of disorders caused by the disruption of normal left-right (L-R) asymmetry of the thoracic or abdominal visceral organs. (ahajournals.org)

The current study used functional magnetic resonance imaging (fMRI) to assess neural activity during task preparation and image presentation during different emotion regulation strategies, cognitive reappraisal and expressive suppression, in PTSD. (springer.com)
The potential of functional MRI (fMRI) to identify changes in cortical activation patterns associated with different levels of recovery has been demonstrated in several studies probing functional consequences of brain damage. (ahajournals.org)
We therefore used fMRI and an active and passive ankle dorsiflexion paradigm to test for cortical functional reorganization in patients with gait impairment and chronic disability after stroke. (ahajournals.org)
Our aims were to use ankle dorsiflexion as an analog of hand flexion-extension to test for evidence of potentially compensatory activation in patients with lower limb paresis after stroke as has been found for the upper limb and to determine whether interindividual differences in the poststroke fMRI response are correlated with the degree of functional impairment of the lower limb. (ahajournals.org)
We hypothesized that different epileptogenic lesions are related to distinct alterations in the functional language connectome detected by fMRI. (ajnr.org)
Laterality indices based on fMRI activation maps failed to discriminate among patient groups. (ajnr.org)
This functional magnetic resonance imaging (fMRI) study demonstrated significant differences in activation of hypothalamic-pituitary-adrenal (HPA) circuitry in adult women with attenuation during ovulation and increased activation during early follicular phase. (jneurosci.org)
We performed functional magnetic resonance imaging (fMRI) to investigate the neural correlates of tactile SJ using tactile number judgement as a time-irrelevant control task. (nature.com)
In our previous functional magnetic imaging (fMRI) study 9 , we directly compared the neural correlates of tactile TOJ with those of SJ. (nature.com)
The extremely variable neurocognitive profiles in surgical epilepsy patients cannot be fully explained by extent of resection, fiber integrity, or current task-based functional MRI (fMRI). (thejns.org)
Functional connectivity, activation maps, and laterality indices for language dominance were analyzed from fMRI data. (thejns.org)
Methods 57 patients with epilepsy were identified with language functional MRI (fMRI) and diffusion MRI acquisition. (bmj.com)
In individual subjects, some studies have shown a correlation between the volume of the arcuate fasciculus tract and language lateralisation, determined by the WADA test 4 and by functional MRI (fMRI)I, 5 while others have not found a consistent association. (bmj.com)
ABSTRACT: Neural activity during language production in aphasia typically has been measured using functional magnetic resonance imaging (fMRI) during silent production tasks. (ufl.edu)
Functional magnetic resonance imaging (fMRI) can be used to non-invasively map language function in the human brain. (edu.au)
An fMRI study of the relative laterality of dominant and non-dominant hand sensory function. (edu.au)
WASHINGTON - (December 11, 2017) - Functional magnetic resonance imaging (fMRI) has allowed researchers to map the memory functions that are often impaired within the brains of children with epilepsy. (eurekalert.org)
A second study demonstrated the ability of functional connectivity analysis within a resting-state fMRI to assess language laterality, meaning to help determine the dominant side of the brain controlling language, when compared with the current standard of a language-task fMRI measure. (eurekalert.org)
The study found that when compared with typical language assessment tasks, resting state fMRI functional connectivity analysis matched the results of the task activity findings slightly more than two thirds of the time. (eurekalert.org)
While more research is needed, the study succeeded in demonstrating the potential of data-driven methods to establish reliable language laterality even without a task-based fMRI. (eurekalert.org)
To investigate this issue, we scanned younger and older adults with functional magnetic resonance imaging (fMRI) while performing three different tasks: working memory, visual attention and episodic retrieval. (diva-portal.org)
4. - 5 The neuroimaging techniques such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) have been widely used to image brain functions for many neurodegenerative diseases. (spiedigitallibrary.org)
Previous studies to determine memory lateralization with functional MR imaging (fMRI) have used encoding or recall tasks. (ajnr.org)
2 - 5 In recent years, there has been an increasing interest in the utility of functional MR imaging (fMRI) for presurgical evaluation of memory. (ajnr.org)
This is undertaken using a variety of methods including studying patients in whom the hemispheres have been surgically separated (a callosotomy or split brain), functional magnetic resonance (fMRI) and diffusion tensor imaging (DTI), and event-related potentials (ERP). (plymouth.ac.uk)

In right TLE, left frontal language dominance correlated with good semantic verbal fluency before and after surgery, and left fronto-temporal language laterality predicted good naming outcome. (thejns.org)
Measurement of language laterality using functional transcranial Doppler ultrasound: a comparison of different tasks. (ox.ac.uk)
The data-driven method of identifying language laterality through functional connectivity analysis was developed previously at Children's National and applied in this setting to test its ability to map the dominant regions of the brain controlling language. (eurekalert.org)

The clinical spectrum of ciliopathies affecting motile cilia spans impaired mucociliary clearance in the respiratory system, laterality defects including heart malformations, infertility and hydrocephalus. (nih.gov)
Using linkage analysis and whole exome sequencing, we identified two recessive loss-of-function MNS1 mutations in five individuals from four consanguineous families: 1) a homozygous nonsense mutation p.Arg242* in four males with laterality defects and infertility and 2) a homozygous nonsense mutation p.Gln203* in one female with laterality defects and recurrent respiratory infections additionally carrying homozygous mutations in DNAH5. (nih.gov)
Consistent with the laterality defects observed in these individuals, we found Mns1 to be expressed in mouse embryonic ventral node. (nih.gov)
Overall, we demonstrate that MNS1 deficiency in humans causes laterality defects (situs inversus) and likely male infertility and that MNS1 plays a role in the ODA-DC assembly. (nih.gov)
Perturbations on the Left-Right axis establishment lead to laterality defects, with frequently associated Congenital Heart Diseases (CHDs). (biomedcentral.com)
Indeed, in the last decade, it has been reported that the etiology of isolated cases of CHDs or cases of laterality defects with associated CHDs is linked with variants of genes involved in the Nodal signaling pathway. (biomedcentral.com)
Altogether, our results provide new insight into the molecular mechanism of the laterality defects and related CHDs, priming for the first time DAND5 as one of multiple candidate determinants for CHDs in humans. (biomedcentral.com)
Laterality defects are developmental disorders resulting from aberrant left/right patterning. (biologists.org)
It is compatible with automated and quantitative image analyses, which is essential to compare mutant phenotypes with incomplete penetrance and to gain mechanistic insight into laterality defects. (biologists.org)
Laterality defects are developmental disorders caused by impaired left-right patterning. (biologists.org)
Laterality Defects in Genome-Edited F0 myo1d Mutant Tadpoles (A) Schematic depicting Myo1d protein structure (sgRNA sites indicated). (xenbase.org)
To identify genetic mutations causing cardiac laterality defects. (ahajournals.org)
We performed a genome-wide linkage analysis in patients with cardiac laterality defects from a consanguineous family. (ahajournals.org)
We performed mutation analysis of NPHP4 in 146 unrelated patients with similar cardiac laterality defects. (ahajournals.org)
Forty-one percent of these patients also had laterality defects of the abdominal organs. (ahajournals.org)
Cardiac laterality defects were partially rescued by human NPHP4 mRNA, whereas mutant NPHP4 containing genetic variants found in patients failed to rescue. (ahajournals.org)
NPHP4 mutations are associated with cardiac laterality defects and heterotaxy. (ahajournals.org)
Laterality defects have been linked to ciliary motility by the observation that 48% of individuals with primary cilia dyskinesia also had situs inversus totalis and 6% had heterotaxy. (ahajournals.org)
The inversus viscerum ( iv ) mouse has a mutation in the ciliary left-right dynein ( lrd ) gene and often develops laterality defects. (ahajournals.org)
A potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome. (xenbase.org)
Previous studies suggest that the suppression of Pitx2 gene in the left LPM is a potential cause of cardiac/laterality defects in Oculo-Facio-Cardio-Dental (OFCD) syndrome, which is known to be caused by mutations in BCL6 co-repressor ( BCOR ) gene. (xenbase.org)
These studies indicated that uncontrolled Notch activity in the left LPM caused by dysfunction of BCOR may result in cardiac/laterality defects of OFCD syndrome. (xenbase.org)

The term laterality refers to the preference most humans show for one side of their body over the other. (wikipedia.org)

This study investigated the phenomenon of lower extremity functional asymmetries in a group of competitive male distance runners ( N = 29). (humankinetics.com)
Data analysis revealed significant asymmetries for both lower extremity functional parameters. (humankinetics.com)
The laterality patterns of functional asymmetries were found to be consistent and independent of the conventional upper and lower extremity lateral preferences. (humankinetics.com)
2018. The functional and structural asymmetries of the superior temporal sulcus. (uib.no)
Anatomical and functional asymmetries are widespread in the animal kingdom [1, 2]. (xenbase.org)
This excellent book celebrates Richard J. Andrew's important contributions to the study of lateralization by considering recent research exploring functional brain asymmetries in a range of vertebrate species. (cambridge.org)
Cognitive control processes and functional cerebral asymmetries: association with variation in the handedness-associated gene LRRTM1. (uio.no)

The data suggest the hemispheric laterality in the slow wave origin. (nih.gov)
Functional changes in inter- and intra-hemispheric cortical processing underlying degraded speech perception. (nih.gov)
2000 , 2001 ) provide evidence for enhanced local processing in large-brained mammals and suggest that greater structural and functional lateralization may arise from increased intrahemispheric connections and hemispheric isolation via reduced commissural linkage. (springer.com)
2012 ) would be predictive of increased hemispheric lateralization and functional independence of the cerebral hemispheres. (springer.com)

People with schizophrenia may show differences in handedness or footedness, as well as altered visual and auditory dominance that may reflect abnormalities in brain laterality and dominance. (edu.au)
As a reliable and valid measures of perceptual auditory laterality, dichotic listening has been successfully applied in studies in many countries and languages. (cambridge.org)
Voicing" explained 69% and 18% of the variance in the perceptual auditory laterality in the Norwegian and the Estonian sample, respectively. (cambridge.org)
Previous studies suggest that at poorer signal-to-noise ratios (SNRs), auditory cortical event-related potentials are weakened, prolonged, and show a shift in the functional lateralization of cerebral processing from left to right hemisphere. (nih.gov)
The book contains sections on animal models and basic functions, neuroimaging and brain stimulation studies, visual laterality, auditory laterality, emotional laterality, neurological disorders, and psychiatric disorders. (mit.edu)

2015. Laterality and mental disorders in the postgenomic age - A closer look at schizophrenia and language lateralization. (uib.no)
Recognition of these functional constraints led to the hypothesis that large-brained mammals should exhibit greater structural and functional brain lateralization. (springer.com)
Indeed, structural, functional, and behavioral lateralization has been observed throughout the Cetacea, including both the Odontoceti (echolocating toothed whales, dolphins, and porpoises) and Mysticeti (non-echolocating baleen whales). (springer.com)
Functional lateralization is presumably brought about by the diversification of neuronal function on a subanatomical level, such as differential gene expression in bilaterally symmetric structures. (genetics.org)
To better understand change to interhemispheric interaction and cerebral laterality with age we are investigating the relationship between age-related change to brain microstructural connectivity, functional lateralization, and cognitive performance. (plymouth.ac.uk)

Previous research on the predatory behaviour of the scale-eating Lake Tanganyika cichlid Perissodus microlepis indicates behavioural laterality that reflects asymmetric jaw morphology. (biologists.org)
We investigated stomach contents and behavioural laterality of predation in aquarium to clarify the functional roles and evolution of laterality in cichlids. (biologists.org)
Taken together, this study provides new insights into the functional roles of behavioural laterality: predatory fish aiming for prey that show escape behaviours frequently exhibit lateralized behaviour in predation. (biologists.org)
This is interesting because it suggests a functional relationship between the shape of the brain and behavioural laterality", says Schneider. (eurekalert.org)

and functional magnetic resonance imaging for measuring changes attributable to CBF. (oup.com)
Differential effects of deep sedation with propofol on the specific and nonspecific thalamocortical systems: a functional magnetic resonance imagin. (nih.gov)
The authors studied the effect of propofol on thalamocortical functional connectivity in the specific and nonspecific systems, using functional magnetic resonance imaging. (nih.gov)
At the UMC he also established various lines of research, mostly using functional Magnetic Resonance Imaging. (umcutrecht.nl)
Effects of vision restoration training on early visual cortex in patients with cerebral blindness investigated with functional magnetic resonance imaging. (umcutrecht.nl)
Magnetic source imaging (MSI) or magnetoencephalography (MEG) is a non-invasive functional imaging technique in which the weak magnetic forces associated with the electrical activity of the brain are monitored externally on the scalp, i.e. (aetna.com)

An asymmetric or lateralized brain is characterized by anatomical or functional differences between its bilateral components, such as the cerebral hemispheres, cortical areas, or cerebral white matter tracts. (springer.com)
Research in the Laterality Lab is aimed at establishing how perceptual, cognitive, and motor processes are integrated between the two cerebral hemispheres of the brain. (plymouth.ac.uk)

Conclusions: The functional-rTMS protocol enhanced cortical excitability following a single-session and after repeated sessions and improved steadiness, whereas the passive stimulation protocol tended to decrease excitation and no improvements in steadiness were observed. (iospress.com)

Brain laterality in schizophrenia has been examined through the application of functional neuroimaging methods. (oup.com)
Recent advances in basic and clinical neuroscience provide an opportunity for focused application of functional imaging in neurobiological studies of schizophrenia. (oup.com)
The purpose of this study is to assess the hemodynamic changes of the PFC and discriminant analysis between schizophrenia patients and healthy controls during VFT task by utilizing functional optical topography. (spiedigitallibrary.org)

In others words, even in children that born with CHDs and that do not present others extracardiac laterality abnormalities, the etiology of these CHDs could arise from subtle faults in the formation of the left-right axis. (biomedcentral.com)

We interpret this as suggesting that normally there is linkage between cardiac and visceral organ laterality. (hindawi.com)
The prognosis of heterotaxy mainly depends on the cardiac malformation, which can be complex with profound functional effects, such as abnormal oxygen supply or obstructed blood flow. (biologists.org)
Depletion of nphp4 disrupted L-R patterning as well as cardiac and gut laterality. (ahajournals.org)

Here we examine the evolution and development of craniofacial morphology and laterality among Lake Tanganyika scale-eating cichlids. (biomedcentral.com)

2017. Arterial spin labelling shows functional depression of non-lesion tissue in chronic Wernicke's aphasia. (uib.no)

An assessment conducted by the BlueCross BlueShield Technology Evaluation Center (2003) concluded that there is insufficient evidence to render conclusions regarding the effect of MSI/MEG on health outcomes for either pre-surgical localization of seizure origin or pre-surgical functional mapping. (aetna.com)
Thalamic functional connectivity predicts seizure onset laterality in individual TLE patients: Application of a biomarker development strategy, Neuroimage: Clinical, doi: 10.1016/j.nicl.2014.08.002. (txstate.edu)

Methods: Twelve stroke survivors were randomized into functional-rTMS or passive-rTMS conditions. (iospress.com)

The syndrome of primary ciliary dyskinesia (PCD, also known as Kartagener's syndrome or immotile cilia syndrome) is a spectrum of conditions caused by a failure of mucociliary clearance related to congenital, structural or functional ciliary abnormalities. (ersjournals.com)

The prevalence of laterality in nature suggests that bilateral symmetry may, in fact, be more superficial than originally thought and, while much is known about the developmental genetic basis for normal asymmetric development of the visceral organs and brain, comparatively little is known about the genetic basis of laterality in normally paired structures. (biomedcentral.com)
Both headache laterality and headache type interact with the degree of comorbidity with higher impairment in patients with left-sided and bilateral headaches as well as in patients with migraine or cluster headache. (frontiersin.org)
Functional connectivity analysis revealed the most extended language network alterations in left mesiotemporal sclerosis (involving the left temporal pole, left inferior frontal gyrus, and bilateral premotor areas). (ajnr.org)

Task-based activation maps (laterality indices) and functional connectivity analysis (global and connectivity strengths between language areas) were correlated with language scores. (ajnr.org)

Findings in the field of neuroendocrinology, which explores the functional relationships between hormones and the brain, have indicated that the release of testicular (androgens) and ovarian (estrogens) hormones during critical periods of brain development exert a profound effect on the genesis and survival of neurons in specific brain areas, resulting in sex differences in reproductive behaviors. (encyclopedia.com)
Differences in gcy expression patterns in the ASE neurons of C. briggsae arise from a difference in cis- regulatory elements and trans- acting factors that control ASE laterality. (genetics.org)
In sum, our results indicate the existence of a surprising multitude of putative chemoreceptors in the gustatory ASE neurons and suggest the existence of a substantial degree of laterality in gustatory signaling mechanisms in nematodes. (genetics.org)

For this purpose we study how reward circuits modulate executive function (self-control), interoception, and motivation in the normal human brain including an understanding of the role of brain dopamine signaling, functional brain network interactions and genetics. (nih.gov)

In these studies, genetic mutations or pharmacological blockade led to functional reorganization of the circuits, and crossed excitation was proposed to couple left-right motor rhythms in synchrony. (jneurosci.org)
The central aim of this research is to determine whether individual differences in age-related cognitive decline are reflected in functional reorganization in the brain, and whether these changes are mediated by the degree of structural preservation. (plymouth.ac.uk)

Functional findings were not explained by the extent of resection or integrity of major white matter tracts. (thejns.org)
Functional connectivity analysis contributes unique insight into bihemispheric remodeling processes of language networks after epilepsy surgery, with characteristic findings in left and right TLE. (thejns.org)

Our primary finding was increased cortical activation with increasing functional impairment. (ahajournals.org)

3-7 Thus, motor control ( i.e. , the command center for movements regardless of the laterality of the effectors involved) resides in the hemisphere which handles respiration and speech at the same time. (asahq.org)

The functional neuroanatomy of event related potentials. (springer.com)

The aim of this study was to assess the relationship between the degree of unilateral spatial neglect during the acute phase of stroke and long-term functional independence. (scielo.br)
This was a prospective study of right ischemic stroke patients in which the independent variable was the degree of spatial neglect and the outcome that was measured was functional independence. (scielo.br)
The best chance of functional independence decreased with increasing star cancellation test scores (OR=0.86 [0.78-0.96], p =0.006) corrected for the stroke severity, which was a confounding factor that had a statistically negative association with independence (OR=0.66 [0.48-0.92], p =0.017). (scielo.br)
The severity of unilateral spatial neglect in acute stroke worsens the degree of long-term disability and functional independence. (scielo.br)
The main areas involved in USN are related to the right hemisphere, such as lesions in the right posterior parietal lobe ( 11 - 12 ), and individuals with USN after stroke present with major functional disabilities as well as decreased rates of adherence to rehabilitation programs ( 13 - 15 ). (scielo.br)
We appreciate Alves et al for their comments on our article, Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial. (ahajournals.org)
However, until recently, results were conflicting because most studies failed to adjust their analyses for variables known to impact on stroke death and functional outcome such as stroke severity or the volume of infarcted brain tissue. (ahajournals.org)
It was hypothesized that stroke laterality was a predictor. (iospress.com)
Stroke laterality was not associated. (iospress.com)
Using a large stroke cohort and a machine-learning approach, we show that visual memory and verbal memory deficits are better predicted by functional connectivity than by lesion location, and visual and motor deficits are better predicted by lesion location than functional connectivity. (pnas.org)
These results shed light on the complementary value of structural vs. functional accounts of stroke, and provide a physiological mechanism for general multidomain deficits seen after stroke. (pnas.org)
We measured resting functional connectivity (FC), lesion topography, and behavior in multiple domains (attention, visual memory, verbal memory, language, motor, and visual) in a cohort of 132 stroke patients, and used machine-learning models to predict neurological impairment in individual subjects. (pnas.org)
Objectives The relationship between stroke topography (ie, the regions damaged by the infarct) and functional outcome can aid clinicians in their decision-making at the acute and later stages. (bmj.com)
We sought to determine which brain regions are associated with good functional outcome at 3 months in patients with left-sided and right-sided stroke treated by endovascular treatment using the diffusion-weighted imaging-Alberta Stroke Program Early CT Score (DWI-ASPECTS). (bmj.com)

Functional optical topography (fOT), imaging based on functional near-infrared spectroscopy measurement, is an another noninvasive neuroimaging technique that provides continuous recording of brain hemodynamic activity with detection of oxy- and deoxy-hemoglobin concentration changes. (spiedigitallibrary.org)

Because this requires separate neural supplies to these two strands of frontalis, from a functional viewpoint this should be regarded as two not one muscle. (scholarpedia.org)

Continued work on the developmental genetic basis of laterality in the Perissodini will facilitate a better understanding of the evolution of this unique group of fishes, as well as of left-right axis determination among vertebrates in general. (biomedcentral.com)
Here we report a genetic screen to discover mutations which perturb organ laterality. (hindawi.com)
Finally, genetic interference experiments demonstrated a functional interaction between the core planar cell polarity signaling gene vangl2 and myo1d in LR axis formation. (xenbase.org)

Further, we show that the evolutionary history of the Perissodini is characterized by an accentuation of craniofacial laterality such that certain taxa show elaborate sided differences in craniofacial shape consistent with the sub-partitioning of function between sides of the head during attacks. (biomedcentral.com)

The method can also be applied to quantitatively assess laterality of other brain functions. (edu.au)

Since the early days of neuroscience, the relative merit of structural vs. functional network accounts in explaining neurological deficits has been intensely debated. (pnas.org)
Thus when decomposing facial behaviors, it is important to understand them from the perspective of functional, not structural anatomy (i.e., how the muscles function in a living, not dead, individual). (scholarpedia.org)

Based on these data, patients were categorized according to headache type and headache laterality, and their clinical characteristics were compared with tinnitus patients, who did not report comorbid headaches. (frontiersin.org)
As a clinical neurologist with interest in laterality of motor control, I read the review by Leffert and Schwamm 1 regarding neuroaxial anesthesia in parturients with intracranial pathology. (asahq.org)

Functional connectivity was determined as the temporal correlation of blood oxygen level-dependent signals with seed regions defined within the specific and nonspecific thalamic nuclei. (nih.gov)
Experimental paradigm and the seeding of the specific and nonspecific thalamic nuclei for functional connectivity analysis. (nih.gov)
The relative density and functional significance (in epileptogenesis) of thalamic projections to MTL subregions, however, remains to be determined. (semanticscholar.org)

The relationship between unilateral spatial neglect and functional independence was analyzed using multiple logistic regression that was corrected for confounding factors. (scielo.br)

In fact, in the majority of cases presenting laterality disorders, a complex heart malformation is also observed, suggesting that CHDs could be due to a laterality defect in the formation of the heart [ 7 ]. (biomedcentral.com)

Craniofacial laterality in the scale-eating specialist Perissodus microlepis was found to be evident early in development and exhibited a unimodal distribution, which is contrary to the adult condition where jaw laterality has been described as a discrete, bimodal antisymmetry. (biomedcentral.com)

Propofol conferred differential changes in functional connectivity of the specific and nonspecific thalamocortical systems, particularly in left hemisphere, consistent with the verbal nature of stimuli and task. (nih.gov)
Shall be consistent with any laterality information contained in Primary Anatomic Structure Modifier Sequence (0008,2230), Anatomic Region Modifier Sequence (0008,2220), and/or Laterality (0020,0060), if present. (nema.org)
The occipital reduction is consistent with the view that sensory processing decline is a common cause in cognitive aging, and the prefrontal increase may reflect functional compensation. (diva-portal.org)

These are dogs that generally survive by scavenging, raising the possibility that domesticated dogs have not maintained a fully functional repertoire of hunting behaviors. (scientificamerican.com)

That laterality decisions of organs may be independently perturbed, as in the Class 3 mutation, indicates that there are distinctive pathways for reception and organotypic interpretation of the global signals. (hindawi.com)

Pataraia et al (2005) studied the functional organization of the inter-ictal spike complex in 30 patients with mesial temporal lobe epilepsy (MTLE) using combined MEG/EEG recordings. (aetna.com)
While I was a Research Assistant Professor at Dartmouth I continued to test split-brain patients and broadened my research to incorporate functional MRI, electroencephalography, and diffusion-tensor imaging. (plymouth.ac.uk)

Approximate statistics are below: Favoring right hand: 88.2% Favoring right foot: 81.0% Favoring right eye: 71.1% Favoring right ear: 59.1% Same hand and foot: 84% Same ear and eye: 61.8% Laterality of motor and sensory control has been the subject of a recent intense study and review. (wikipedia.org)
Because of this functional division of the left and right sides of the body and of the space that surrounds it, the processing of information in the sensory cortices is essentially identical. (wikipedia.org)

Thus, one in five persons has a handedness that is the opposite for which they are wired (per laterality of command center or brainedness, as determined by reaction time study mentioned above). (wikipedia.org)
This volume bears witness to a groundswell of interest in brain laterality and its implications for the study of the mind. (cambridge.org)

Anatomy23

Organisms8

Diseases16

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment12

Psychiatry and Psychology17

Phenomena and Processes14

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science2

Health Care3

Geographicals1

Central peptidergic neurons are hyperactive during collateral sprouting and inhibition of activity suppresses sprouting. (1/6942)

Retinotopic mapping of lateral geniculate nucleus in humans using functional magnetic resonance imaging. (2/6942)

Command-related distribution of regional cerebral blood flow during attempted handgrip. (3/6942)

Language processing is strongly left lateralized in both sexes. Evidence from functional MRI. (4/6942)

Selective horizontal dysmetropsia following prestriate lesion. (5/6942)

The role of ventral medial wall motor areas in bimanual co-ordination. A combined lesion and activation study. (6/6942)

Multicentre European study of thalamic stimulation in parkinsonian and essential tremor. (7/6942)

Cognitive outcome after unilateral pallidal stimulation in Parkinson's disease. (8/6942)

Functional Laterality

Dominance, Cerebral

Nodal Protein

Situs Inversus

Body Patterning

Epithalamus

Heterotaxy Syndrome

Beluga Whale

Habenula

Potoroidae

Left-Right Determination Factors

Dichotic Listening Tests

Twins, Conjoined

Zebrafish

Language

New Caledonia

Zebrafish Proteins

Growth Differentiation Factor 1

Cilia

Magnetic Resonance Imaging

Posterior Cerebral Artery

Amobarbital

Crows

Manufactured Materials

Brain Mapping

Kartagener Syndrome

Embryo, Nonmammalian

Epilepsy, Temporal Lobe

Gene Expression Regulation, Developmental

Endocardial Cushion Defects

Brain

Gestures

Language Tests

Imagination

Pitch Discrimination

Heart Defects, Congenital

Retinal Neoplasms

Cerebral Cortex

Magnetoencephalography

Auditory Perception

Axonemal Dyneins

Retinoblastoma

Anisometropia

Temporal Lobe

Epilepsy

Acoustic Stimulation

Cichlids

Fetal Heart

Xenopus Proteins

Pineal Gland

Rotation

Image Processing, Computer-Assisted

Psychomotor Performance

Viscera

Organogenesis

Jaw

Forelimb

Electroencephalography

Mesoderm

Somites

In Situ Hybridization

Aphasia

Activin Receptors

Schizophrenia

Behavior, Animal

Tinnitus

Reaction Time

Verbal Behavior

Pan troglodytes

Neuropsychological Tests

Heart

Retrospective Studies

Frontal Lobe

Hallucinations

Gastrula

Homeodomain Proteins

Parietal Lobe

Morphogenesis

Analysis of Variance

Hand