Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.Iodine Compounds: Inorganic compounds that contain iodine as an integral part of the molecule.Iodine Radioisotopes: Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.Goiter, Endemic: A form of IODINE deficiency disorders characterized by an enlargement of the THYROID GLAND in a significantly large fraction of a POPULATION GROUP. Endemic goiter is common in mountainous and iodine-deficient areas of the world where the DIET contains insufficient amount of iodine.Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).Thyroid Gland: A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.Potassium Iodide: An inorganic compound that is used as a source of iodine in thyrotoxic crisis and in the preparation of thyrotoxic patients for thyroidectomy. (From Dorland, 27th ed)Sodium Chloride, Dietary: Sodium chloride used in foods.Povidone-Iodine: An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.Deficiency Diseases: A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)Iodides: Inorganic binary compounds of iodine or the I- ion.Iodophors: Complexes of iodine and non-ionic SURFACE-ACTIVE AGENTS acting as carrier and solubilizing agent for the iodine in water. Iodophors usually enhance bactericidal activity of iodine, reduce vapor pressure and odor, minimize staining, and allow wide dilution with water. (From Merck Index, 11th ed)Thyrotropin: A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.Congenital Hypothyroidism: A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.Thyroid Function Tests: Blood tests used to evaluate the functioning of the thyroid gland.Iodized Oil: A preparation of oil that contains covalently bound IODINE. It is commonly used as a RADIOCONTRAST AGENT and as a suspension medium for CHEMOTHERAPEUTIC AGENTS.ThyroglobulinIodine Isotopes: Stable iodine atoms that have the same atomic number as the element iodine, but differ in atomic weight. I-127 is the only naturally occurring stable iodine isotope.Thyroid Diseases: Pathological processes involving the THYROID GLAND.Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA.IodoproteinsThyroid Hormones: Natural hormones secreted by the THYROID GLAND, such as THYROXINE, and their synthetic analogs.Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.Iodide Peroxidase: A hemeprotein that catalyzes the oxidation of the iodide radical to iodine with the subsequent iodination of many organic compounds, particularly proteins. EC 1.11.1.8.Perchlorates: Compounds that contain the Cl(=O)(=O)(=O)O- structure. Included under this heading is perchloric acid and the salts and ester forms of perchlorate.Diiodotyrosine: A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE).Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.Sodium Iodide: A compound forming white, odorless deliquescent crystals and used as iodine supplement, expectorant or in its radioactive (I-131) form as an diagnostic aid, particularly for thyroid function tests.Anti-Infective Agents, Local: Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.Nutritional Status: State of the body in relation to the consumption and utilization of nutrients.Iodates: Inorganic salts of iodic acid (HIO3).Thyroiditis, Autoimmune: Inflammatory disease of the THYROID GLAND due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-CELLS and thyroid AUTOANTIBODIES. The clinical signs can range from HYPOTHYROIDISM to THYROTOXICOSIS depending on the type of autoimmune thyroiditis.Monoiodotyrosine: A product from the iodination of tyrosine. In the biosynthesis of thyroid hormones (THYROXINE and TRIIODOTHYRONINE), tyrosine is first iodized to monoiodotyrosine.Republic of BelarusFree Radicals: Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.Thyroidectomy: Surgical removal of the thyroid gland. (Dorland, 28th ed)Cyclization: Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)PyransPropanols: Isomeric forms and derivatives of PROPANOL (C3H7OH).Alkadienes: Acyclic branched or unbranched hydrocarbons having two carbon-carbon double bonds.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Alcohols: Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh's Chemical Dictionary, 5th ed)Abbreviations as Topic: Shortened forms of written words or phrases used for brevity.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Dictionaries, ChemicalTerminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Serving Size: A reference measure of food used to identify the calorie and nutrient content in a particular amount of that food. It is defined by an authoritative source, such as the Food Guide Pyramid devised by the UNITED STATES DEPARTMENT OF AGRICULTURE. It is different from PORTION SIZE, which is the amount of food one chooses to eat at a single meal.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Vitamins: Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.Cholecalciferol: Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.Niacinamide: An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
  • Potassium iodide is also not recommended for people with dermatitis herpetiformis and hypocomplementemic vasculitis - conditions that are linked to a risk of iodine sensitivity. (wellprepared.com)
  • Iodometric reaction between iodate, excess iodide, and acid has been used, and the iodine liberated is allowed to react with variamine blue (VB) dye in the presence of sodium acetate to yield a violet-colored species. (springeropen.com)
  • Also, accurate determination of the contribution of iodine from table salt to total dietary intake requires novel methods. (springeropen.com)
  • We aimed to test the hypothesis that the odds of dyslipidemia including elevated total cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol and apolipoprotein B, and lowered high-density lipoprotein (HDL) cholesterol and HDL/LDL ratio are associated with urinary iodine concentration (UIC) in a population perspective. (mdpi.com)
  • The NDA said the 70-130 µg level for infants and children was based on a large epidemiological study in European school-aged children that showed goitre prevalence was lowest for a urinary iodine concentration above 100 µg/L. (nutraingredients.com)
  • Maternal urinary iodine concentration during the first trimester was correlated with the child's IQ at 8 years, and reading ability at 9 years. (newsmax.com)
  • The median urinary iodine concentration (UIC) among Israel's pregnant women, only 61 micrograms iodine/liter and for school-age children, the median of 83 micrograms/liter suggest that the iodine status in Israel is amongst the lowest in the world. (greenprophet.com)
  • The findings, made by an international team of scientists from the United Kingdom, Germany, United States, Switzerland, France and the Netherlands, reveal iodine's biological role as an inorganic antioxidant--the first to be described in a living system--and also point to the intriguing effects of iodine in scavenging free radicals in human blood cells. (innovations-report.com)
  • This volume summarizes the current understanding of the effects of iodine deficiency as well as iodine excess. (springer.com)
  • This up-to-date volume explores both the effects of iodine deficiency as well as the best strategies for IDD prevention. (springer.com)
  • The aim of this study was to analyze the uptake and effects of iodine in a preclinical model of prostate cancer (transgenic adenocarcinoma of the mouse prostate [TRAMP] mice/SV40-TAG antigens), which develops cancer by 12 wks of age. (nih.gov)
  • Other studies have shown that selenium protects against the effects of iodine toxicity and prevents the triggering and flaring of autoimmune disease that excess iodine without selenium can cause. (chriskresser.com)
  • As I've described in this article, it's crucial that you also take 200 mcg of selenium per day during this protocol to protect against the potentially adverse effects of iodine supplementation, especially if you have autoimmune thyroid disease. (chriskresser.com)
  • If there is a contraindication to chlorhexidine, tincture of iodine , an iodophor, or 70% alcohol can be used as alternatives" (CDC, 2011, p. (thefreedictionary.com)
  • PVP-I is a broad spectrum biocidal agent which is highly soluble than other iodine compounds like Tincture of iodine and Lugols solution. (thefreedictionary.com)
  • On its own, a tincture of iodine is a dark yellow colour. (thefreedictionary.com)
  • The travel doctor gave me a tincture of iodine kit that I could use to disinfect water, if needed, when I was in Tanzania. (thefreedictionary.com)
  • Tincture of iodine is a solution of iodine and potassium iodide in alcohol. (thefreedictionary.com)
  • tincture of iodine and iodoform iodoform , CHI 3 , yellow crystalline solid that has a penetrating odor. (thefreedictionary.com)
  • He claimed in 1915 that Grossich had been using a liquid akin to Liquor Iodi Fortis, and that it was he, Stretton, who had introduced the method using Tincture of Iodine BP which came to be used across the world. (wikipedia.org)
  • USP Tincture of Iodine is defined in the U.S. National Formulary (NF) as containing in each 100 mL, 1.8 to 2.2 grams of elemental iodine, and 2.1 to 2.6 grams of sodium iodide. (wikipedia.org)
  • As both USP solutions contain elemental iodine, which is moderately toxic when ingested in amounts larger than those required to disinfect water, tincture of iodine is sold labelled "for external use only," and used primarily as a disinfectant. (wikipedia.org)
  • Tincture of iodine is often found in emergency survival kits, used both to disinfect wounds and to sanitize surface water for drinking. (wikipedia.org)
  • Nevertheless, the iodide in tincture of iodine used as a water disinfectant does supply more than adequate nutritional iodine, perhaps 30 or more times the recommended daily allowance per liter or quart. (wikipedia.org)
  • I have been getting new little blisters almost every day and it is likely due to the fact that I didn't know that eggs have fairly high amounts of iodine in them. (celiac.com)
  • Note: Sea vegetables contain large amounts of iodine - sometimes even too much for regular consumption. (babycenter.com)
  • While fish and sea vegetables can be good sources of iodine, they are often not accessible or utilized. (apexhealth.club)
  • Good sources of iodine are seaweed and iodized salt. (medicalnewstoday.com)
  • Cruciferous vegetables are also good sources of iodine. (medicalnewstoday.com)
  • Now the main sources of iodine are iodate minerals, natural brine deposits left by the evaporation of ancient seas and brackish (briny) waters from oil and salt wells. (rsc.org)
  • But, as these drinks were not from a market leader, most consumers will probably not get enough iodine in their diet from this source. (open.edu)
  • Yaniv Ovadia, the doctoral student and registered dietitian who performed the study, said, "Individuals can improve their iodine status through increased consumption of iodine-rich foods such as milk, dairy and salt water fish. (greenprophet.com)
  • "For years, it was believed that iodine deficiency was a problem restricted to certain geographic areas and high-risk conditions (poverty, malnourishment) but this is not valid anymore," ​explained Velasco. (nutraingredients-usa.com)
  • I would never be without a bottle of lugols iodine, it is a superb product and very cheap from your company. (hyperdrug.co.uk)
  • I'm now on 50 mg iodine taken as lugols solution and I take selenium 400 mcg, magnesiummalate 1000 mg, 3 gr vitamin c und sea salt 3 times a day. (curezone.com)
  • Some people may benefit from supplementing with high doses of iodine short term, and these are some great options to choose from. (healthline.com)
  • Keep in mind that you should not attempt to take exceptionally high doses of iodine without guidance from a qualified healthcare provider. (healthline.com)
  • Youths may be most affected by iodine-131 because their thyroid glands are still growing and developing. (harvard.edu)
  • Because the thyroid glands of those affected by fallout from the failing nuclear power plants may be "full" of natural iodine, iodine-131 may not be able to get into the gland, giving them natural protection against radiation-induced thyroid cancer. (harvard.edu)
  • For people who cannot or will not eat these alternative sources - such as vegans or those who dislike fish - it can be hard to meet the recommended iodine intake. (open.edu)
  • From the viewpoint of green and sustainable chemistry, hypervalent iodine and other halogen reagents have gained increasing popularity in metal-free oxidative transformation due to their low toxicity, transition-metal-like reactivity, high stability, easy handling and other benefits. (eurekaselect.com)
  • Akio Saito*, "Hypervalent Iodine-Mediated/Catalyzed Oxidative Cycloisomerization/Annulation of Alkynes for Metal-Free Synthesis of Oxazoles", Current Organic Chemistry (2020) 24: 1. (eurekaselect.com)
  • Chemical Equation Presented) We describe solvent-free reactions for the synthesis of hypervalent iodine reagents and their use in solid-state reactions. (elsevier.com)