Food Hypersensitivity
Milk Hypersensitivity
Immunoglobulin E
Hypersensitivity, Delayed
Drug Hypersensitivity
Molecular cloning and epitope analysis of the peanut allergen Ara h 3. (1/860)
Peanut allergy is a significant IgE-mediated health problem because of the increased prevalence, potential severity, and chronicity of the reaction. Following our characterization of the two peanut allergens Ara h 1 and Ara h 2, we have isolated a cDNA clone encoding a third peanut allergen, Ara h 3. The deduced amino acid sequence of Ara h 3 shows homology to 11S seed-storage proteins. The recombinant form of this protein was expressed in a bacterial system and was recognized by serum IgE from approximately 45% of our peanut-allergic patient population. Serum IgE from these patients and overlapping, synthetic peptides were used to map the linear, IgE-binding epitopes of Ara h 3. Four epitopes, between 10 and 15 amino acids in length, were found within the primary sequence, with no obvious sequence motif shared by the peptides. One epitope is recognized by all Ara h 3-allergic patients. Mutational analysis of the epitopes revealed that single amino acid changes within these peptides could lead to a reduction or loss of IgE binding. By determining which amino acids are critical for IgE binding, it might be possible to alter the Ara h 3 cDNA to encode a protein with a reduced IgE-binding capacity. These results will enable the design of improved diagnostic and therapeutic approaches for food-hypersensitivity reactions. (+info)Involvement of tachykinin receptors in sensitisation to cow's milk proteins in guinea pigs. (2/860)
BACKGROUND: There is growing evidence for a pivotal role for tachykinins in gut neuroimmune interactions. AIMS: To determine whether NK1, NK2, and NK3 tachykinin receptors are involved in milk protein induced allergic sensitisation. METHODS: Eight groups of 12 Dunkin-Hartley guinea pigs (250-300 g) were used. Four groups were sensitised to milk proteins for three weeks. During this period, these animals were injected intraperitoneally each day with NK1 (SR 140333; 0.3 mg/kg), NK2 (SR 48968; 5 mg/kg), or NK3 (SR 142801; 5 mg/kg) receptor antagonist or vehicle. The fifth group had water available instead of milk and was used as a non-sensitised control. The three other groups received the NK receptor antagonists for three weeks but were not sensitised to milk proteins. RESULTS: Sensitised animals treated with NK1 and NK3 receptor antagonists had both lower IgE and IgG serum titres, evaluated by passive cutaneous anaphylaxis, and lower specific IgG serum titres, determined by enzyme linked immunosorbent assay (ELISA), than vehicle treated animals. Sensitisation induced an increase in intestinal mast cell number which was abolished by treatment with the NK1 receptor antagonist. Antigenic challenge-induced jejunal hypersecretion was also blocked by treatment with the NK1 receptor antagonist. CONCLUSION: In guinea pigs, NK1 and NK3 but not NK2 receptors are involved in sensitisation to cow's milk. However, NK1 but not NK3 receptor antagonists abolish both the hypermastocytosis induced by food allergy and the hypersecretion induced by antigenic challenge, suggesting different roles for NK1 and NK3 receptors in the mechanisms of sensitisation to beta-lactoglobulin. (+info)Dental surgeons with natural rubber latex allergy: a report of 20 cases. (3/860)
Latex allergy is becoming a major occupational health issue and dental surgeons are at risk from becoming sensitized to natural rubber latex. A study was conducted to investigate risk factors and glove-related symptoms reported by dentists with natural rubber latex allergy. Twenty dentists, who had undergone serological or dermatological testing for a Type I allergy to latex, were identified from a questionnaire survey. Risk factors investigated were: gender, years in clinical practice, exposure to latex gloves, atopic history and food allergy. The majority of dentists (75%) gave an atopic history. Glove-related adverse reactions ranged from cutaneous to systemic manifestations. All twenty dentists reported itching of the hands in response to latex gloves. One respondent was unable to continue in dental practice because of her glove-related allergies; nineteen dentists were able to continue by using synthetic, non-latex gloves. (+info)Acute liver injury that followed food-dependent exercise-induced anaphylaxis. (4/860)
We describe an unusual case of acute liver injury that followed food-dependent exercise-induced anaphylaxis (FDEIAn). A 45-year-old man who experienced anaphylactic shock induced by postprandial exercise and took alcohol that night was admitted the following day to our hospital because of general fatigue. Laboratory examinations revealed elevated hepatic enzymes (aspartate aminotransferase (AST) 6,110 IU, alanine aminotransferase (ALT) 4,178 IU). He had two similar episodes in the past. We speculated that acute liver injury in this case might be induced by interaction of anaphylactic shock and alcohol. (+info)Allergen mimotopes in food enhance type I allergic reactions in mice. (5/860)
BIP1is a murine IgG antibody capable of enhancing the IgE binding to Bet v 1, the major birch pollen allergen. We have previously generated a mimotope of BIP1, designated Bet mim 1, from a constrained phage display peptide library. We demonstrated that oral immunization of BALB/c mice with the Bet mim 1 mimotope resulted in the induction of Bet v 1-specific IgG. The aim of this study was to test the influence of such an oral immunization with Bet mim 1 on a subsequent type I allergic response to Bet v 1. Phages displaying Bet mim 1 or control mimotopes, or PBS alone, were delivered to BALB/c mice by intragastric gavages prior to systemic sensitization with recombinant Bet v 1 and Al(OH)(3), an adjuvant inducing preferentially IgE antibody responses. Only mice fed with Bet mim 1-phages displayed substantially enhanced type I allergic skin reactivity to Bet v 1, as compared to mice pretreated with control mimotopes or PBS. A gastric digestion assay indicated that Bet v 1 and its homologue from apple, Mal d 1, were degraded within seconds under physiological conditions. In contrast, phage-displayed mimotopes were resistant to digestion. Our data indicate that allergen mimics in the diet that resist digestion, can induce allergen specific IgG able to enhance an allergic response. We therefore conclude that sensitization via the oral route may represent a mechanism for aggravating type I allergic reactions, probably leading to an earlier onset of symptoms even at lower allergen dosage. (+info)Characterisation of immune mediator release during the immediate response to segmental mucosal challenge in the jejunum of patients with food allergy. (6/860)
BACKGROUND: Food allergy is a common complaint among patients with a broad spectrum of abdominal and extra-abdominal symptoms that must be distinguished from other more common non-immunological food intolerances. AIMS: To investigate whether human intestinal hypersensitivity reactions are associated with detectable release of inflammatory mediators from activated cells, which may serve as a biological marker of true allergic reactions. PATIENTS/METHODS: In eight patients with food allergy and seven healthy volunteers, a closed-segment perfusion technique was used to investigate the effects of jejunal food challenge on luminal release of tryptase, histamine, prostaglandin D(2), eosinophil cationic protein, peroxidase activity, and water flux. RESULTS: Intraluminal administration of food antigens induced a rapid increase in intestinal release of tryptase, histamine, prostaglandin D(2), and peroxidase activity (p<0.05 v basal period) but not eosinophil cationic protein. The increased release of these mediators was associated with a notable water secretory response. CONCLUSIONS: These results suggest that human intestinal hypersensitivity reactions are characterised by prompt activation of mast cells and other immune cells, with notable and immediate secretion of water and inflammatory mediators into the intestinal lumen. Analysis of the profile of markers released into the jejunum after food provocation may be useful for the objective diagnosis of food allergy. (+info)Characterization of a core alpha1-->3-fucosyltransferase from the snail Lymnaea stagnalis that is involved in the synthesis of complex-type N-glycans. (7/860)
We have identified a core alpha1-->3-fucosyltransferase activity in the albumin and prostate glands of the snail Lymnaea stagnalis. Incubation of albumin gland extracts with GDP-[(14)C]Fuc and asialo/agalacto-glycopeptides from human fibrinogen resulted in a labeled product in 50% yield. Analysis of the product by 400 MHz (1)H-NMR spectroscopy showed the presence of a Fuc residue alpha1-->3-linked to the Asn-linked GlcNAc. Therefore, the enzyme can be identified as a GDP-Fuc:GlcNAc (Asn-linked) alpha1-->3-fucosyltransferase. The enzyme acts efficiently on asialo/agalacto-glycopeptides from both human fibrinogen and core alpha1-->6-fucosylated human IgG, whereas bisected asialo/agalacto-glycopeptide could not serve as an acceptor. We propose that the enzyme functions in the synthesis of core alpha1-->3-fucosylated complex-type glycans in L. stagnalis. Core alpha1-->3-fucosylation of the asparagine-linked GlcNAc of plant- and insect-derived glycoproteins is often associated with the allergenicity of such glycoproteins. Since allergic reactions have been reported after consumption of snails, the demonstration of core alpha1-->3-fucosylation in L. stagnalis may be clinically relevant. (+info)Alternative treatments for rheumatoid arthritis. (8/860)
Conventional treatments for rheumatoid arthritis (RA) present a number of problems, in terms of both safety and efficacy. A number of different alternative therapies have been studied, including dietary modifications, nutritional supplements, botanicals, and antibiotics. While the response to these treatments is variable and often unpredictable, some patients have shown dramatic improvement or even complete and long-lasting remission. Moreover, alternative therapies, with the exception of antibiotics, have a low incidence of adverse effects. Consideration of these treatment options has the potential to benefit many patients with RA. (+info)Food hypersensitivity, also known as food allergy, is a condition in which the immune system reacts abnormally to certain foods. When a person with food hypersensitivity consumes a food to which they are allergic, their immune system produces antibodies that attack the food as a foreign substance. This can cause a range of symptoms, from mild to severe, including hives, itching, swelling, nausea, vomiting, diarrhea, and difficulty breathing. In severe cases, food hypersensitivity can lead to anaphylaxis, a life-threatening allergic reaction that requires immediate medical attention. Food hypersensitivity is typically diagnosed through a combination of medical history, physical examination, and allergy testing. Treatment typically involves avoiding the foods to which a person is allergic and carrying an epinephrine auto-injector in case of an allergic reaction.
Milk hypersensitivity, also known as lactose intolerance, is a condition in which the body is unable to digest lactose, a sugar found in milk and other dairy products. This can cause symptoms such as bloating, gas, diarrhea, and abdominal pain. Milk hypersensitivity is not the same as an allergy to milk, which is an immune system response to a specific protein in milk. Milk hypersensitivity is more common than milk allergy and can be diagnosed through a lactose tolerance test. Treatment typically involves avoiding dairy products or taking lactase supplements to help digest lactose.
Immunoglobulin E (IgE) is a type of antibody that plays a key role in the immune system's response to allergens and parasites. It is produced by B cells in response to specific antigens, such as those found in pollen, dust mites, or certain foods. When an allergen enters the body, it triggers the production of IgE antibodies by B cells. These antibodies then bind to mast cells and basophils, which are immune cells that are involved in the inflammatory response. When the same allergen enters the body again, the IgE antibodies on the mast cells and basophils bind to the allergen and cause the release of histamine and other inflammatory chemicals. This leads to symptoms such as itching, swelling, and difficulty breathing. IgE is also involved in the immune response to parasites, such as worms. In this case, the IgE antibodies help to trap and kill the parasites by binding to them and marking them for destruction by other immune cells. Overall, IgE is an important part of the immune system's defense against allergens and parasites, but it can also contribute to allergic reactions and other inflammatory conditions when it binds to inappropriate antigens.
Hypersensitivity, delayed, also known as type IV hypersensitivity or cell-mediated hypersensitivity, is a type of immune response that occurs after an initial exposure to a foreign substance, such as a protein or a drug. Unlike immediate hypersensitivity, which occurs within minutes or hours of exposure, delayed hypersensitivity takes several days to develop. In delayed hypersensitivity, immune cells called T cells recognize and remember the foreign substance. When the immune system encounters the same substance again, the T cells become activated and release chemicals that cause inflammation and damage to the tissue where the substance is located. This can lead to symptoms such as redness, swelling, and itching, and in severe cases, can cause tissue damage or even organ failure. Delayed hypersensitivity is often associated with allergic reactions to certain drugs, metals, or chemicals, as well as with certain infections, such as tuberculosis and leprosy. It is also a key component of the immune response to transplanted organs, as the immune system recognizes the foreign tissue and mounts an attack against it.
Drug hypersensitivity is a type of adverse drug reaction that occurs when a person's immune system overreacts to a medication. It can cause a range of symptoms, from mild skin rashes to severe allergic reactions that can be life-threatening. Drug hypersensitivity can be classified into several types, including: 1. Type I hypersensitivity: This is an immediate reaction that occurs within minutes to hours of taking the medication. It is caused by the release of histamine and other chemicals from immune cells, which can cause symptoms such as itching, hives, and swelling. 2. Type II hypersensitivity: This is a delayed reaction that occurs within days to weeks of taking the medication. It is caused by the immune system attacking and destroying cells in the body that are sensitive to the drug. 3. Type III hypersensitivity: This is a more complex reaction that involves the formation of immune complexes in the blood, which can cause inflammation and damage to tissues. 4. Type IV hypersensitivity: This is a chronic reaction that occurs over a longer period of time and is characterized by inflammation and tissue damage. Drug hypersensitivity can be difficult to diagnose because the symptoms can be similar to those of other conditions. It is important for healthcare providers to carefully monitor patients who are taking medications and to discontinue the medication if a hypersensitivity reaction is suspected.
Hypersensitivity
Food allergy
Food intolerance
Allergies in cats
Allergen immunotherapy
Sulfite food and beverage additives
Sulfite
List of allergens
Mushroom hunting
Hypoallergenic dog food
Type I hypersensitivity
Pathophysiology of asthma
Iodine
Immune tolerance
Notoedric mange
Oat sensitivity
Elimination diet
Allergy
Non-carious cervical lesions
Hemorrhagic gastroenteritis
Drug intolerance
Triclosan
Genetically modified food
Annatto
Fruit allergy
Oral allergy syndrome
Food browning
Proactiv
Dentin hypersensitivity
Quinolone antibiotic
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Type II hypersensitivity reacti1
- The pathophysiology of type II hypersensitivity reactions can be broadly classified into three types: Cell depletion or destruction without inflammation Inflammation mediated by complement or Fc receptor Cellular dysfunction by antibodies The process involves a series of immune-mediated events that might take different forms. (wikipedia.org)
Delayed hypersensitivity reaction2
- The fourth type is considered a delayed hypersensitivity reaction because it usually occurs more than 12 hours after exposure to the allergen, with a maximal reaction time between 48 and 72 hours. (wikipedia.org)
- Allergic contact dermatitis is caused by a type IV, T cell-mediated, delayed hypersensitivity reaction in which a foreign substance comes into contact with the skin and is linked to skin protein, forming an antigen complex that leads to sensitization. (aafp.org)
Anaphylaxis1
- Symptoms involved in food allergy reactions can range from gastrointestinal symptoms such as nausea, vomiting and diarrhea or skin reactions such as uticaria, eczema, and itching to respiratory reactions such as asthma or a full systemic response called anaphylaxis or anaphylactic shock. (purehealthsystems.com)
Intolerance9
- Food Intolerance vs. Food Allergy: What's the Difference? (medlineplus.gov)
- Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to antigen. (wikipedia.org)
- Knibb RC, Armstrong A, Booth DA, Platts RG, Booth IW, MacDonald A: Psychological characteristics of people with perceived food intolerance in a community sample. (aerzteblatt.de)
- Food lactose and lactose intolerance is today a hot topic in food and nutrition knowledge. (researchgate.net)
- As scientific knowledge on lactose intolerance has notably advanced in recent decades, the aim of this work was to review the current state of the knowledge on lactose and lactose intolerance, its diagnosis and clinical management, and the various food products that are offered specifically for non-tolerant individuals. (researchgate.net)
- The most common cause of food intolerances is improper or incomplete digestion, as is the case with lactose intolerance. (purehealthsystems.com)
- Those with lactose intolerance are not allergic to milk or dairy, but do exhibit a reaction because they are lacking the enzyme lactase to completely digest these foods. (purehealthsystems.com)
- An allergy involves the immune system, while a food intolerance is a simple reaction to a food's ingredients-often one or more of the colorings, texturizers, or 25 other categories of allowed pet food additives. (onlynaturalpet.com)
- However, the other major symptoms of food allergy that don't usually occur with food intolerance are skin symptoms: itching, redness, rashes, hair loss, and ear infections. (onlynaturalpet.com)
Atopic6
- Low gut microbiota richness and an elevated Enterobacteriaceae/Bacteroidaceae ratio in early infancy are associated with subsequent food sensitization, suggesting that early gut colonization may contribute to the development of atopic disease, including food allergy. (nih.gov)
- Overview of Allergic and Atopic Disorders Allergic (including atopic) and other hypersensitivity disorders are inappropriate or exaggerated immune reactions to foreign antigens. (msdmanuals.com)
- Atopic dermatitis and food hypersensitivity reactions. (medscape.com)
- Prevalence of IgE-mediated food allergy among children with atopic dermatitis. (medscape.com)
- Sampson HA, McCaskill CC. Food hypersensitivity and atopic dermatitis: evaluation of 113 patients. (medscape.com)
- Natural history of food hypersensitivity in children with atopic dermatitis. (medscape.com)
Pathophysiology1
- Crowe SE, Perdue MH: Gastrointestinal food hypersensitivity: basic mechanisms of pathophysiology. (aerzteblatt.de)
Pneumonitis2
- The most common diseases involving a type III hypersensitivity reaction are serum sickness, post-streptococcal glomerulonephritis, systemic lupus erythematosus, farmers' lung (hypersensitivity pneumonitis), and rheumatoid arthritis. (wikipedia.org)
- One worker developed an uncommon immune-mediated lung disease, hypersensitivity pneumonitis, during employment that treating physicians concluded was caused by exposures to organic materials at the facility. (cdc.gov)
Reaction11
- Injectable epinephrine is the drug of choice for the initial management of a food-induced anaphylactic reaction. (medscape.com)
- Ensure that the patient has an emergency contact number available (eg, 911, their physician's office phone number, or a local emergency department) that can be used in the event of a major food-induced allergic reaction. (medscape.com)
- Medication-induced reactions: antibiotics Type II hypersensitivity reaction refers to an antibody-mediated immune reaction in which antibodies (IgG or IgM) are directed against cellular or extracellular matrix antigens with the resultant cellular destruction, functional loss, or damage to tissues. (wikipedia.org)
- The principal feature that separates type III reactions from other hypersensitivity reactions is that in type III reaction, the antigen-antibody complexes are pre-formed in the circulation before their deposition in tissues. (wikipedia.org)
- An immediate and severe allergic reaction to a substance such as a food or drug. (cdc.gov)
- Epinephrine should likely be administered to any patient with a history of a severe allergic reaction as soon as ingestion of the food allergen is discovered and the first symptoms appear (and possibly even before symptoms appear). (medscape.com)
- Treatment is with elimination of the food that triggers the reaction and sometimes oral cromolyn. (msdmanuals.com)
- Adverse reaction to food: assessment by double-blind placebo-controlled food challenge and clinical, psychosomatic and immunologic analysis. (aerzteblatt.de)
- A little over a week ago, a number of readers sent me a link to an FDA safety alert and report of its investigation into Erick's death and another case of a serious hypersensitivity reaction due to intravenous curcumin. (scienceblogs.com)
- It turns out that what likely killed Jade Erick was a hypersensitivity reaction to the use of a component that wasn't pharmaceutical grade and is also known to cause hypersensitivity reactions. (scienceblogs.com)
- The medical name for an allergy is a "hypersensitivity reaction. (onlynaturalpet.com)
Eosinophils1
- EoE is characterized by high accumulations in the esophagus of white blood cells called eosinophils, as well as hypersensitivity to certain foods. (allergicliving.com)
Diagnosis4
- In 2010, Guidelines for the Diagnosis and Management of Food Allergy in the United States were published. (medscape.com)
- These provide evidenced-based, expert panel recommendations for the diagnosis and management of food allergies. (medscape.com)
- Bengtsen U N-BU, Hanson LA, Ahlstedt S: Double blind, placebo controlled food reactions do not correlate to IgE allergy in the diagnosis of staple food related gastrointestinal symptoms. (aerzteblatt.de)
- Therefore, some investigators have used antigen preparations, such as trichophyton, intended for the diagnosis and/or treatment of immediate type hypersensitivity reactions. (cdc.gov)
Pollen2
- Oral allergy syndrome (pollen food allergy syndrome) is caused by proteins in pollens and foods that cross-react (frequently raw fruits and vegetables and nuts). (msdmanuals.com)
- Just to complicate things, these symptoms can also occur with allergies that don't involve food, such as flea bites and pollen, as well as non-allergic conditions. (onlynaturalpet.com)
Allergen5
- The only proven medication therapy against a food allergy is strict elimination of the offending food allergen from the diet and avoidance of any contact with the food by ingestion, skin contact, inhalation, or injection. (medscape.com)
- Educate the patient and family about how to properly read food labels and identify common words used for indicating the presence of the food allergen of concern. (medscape.com)
- A concise written plan for the treatment of allergic reactions resulting from accidental exposure to a patient's food allergen should be developed. (medscape.com)
- Twelve infants (7.2%) were sensitized to ≥ 1 common food allergen at 1 year. (nih.gov)
- Jones SM, Burks AW, Dupont C. State of the art on food allergen immunotherapy: oral, sublingual, and epicutaneous. (medscape.com)
Milk5
- This concern is particularly problematic for foods while they are being cooked, because proteins are dispersed in the steam (eg, frying fish, boiling milk). (medscape.com)
- The majority of relatives were satisfied with the gradual improvement of patients observed by reduction on the severity of symptoms and tolerance of milk traces within foods. (bvsalud.org)
- milk hypersensitivity. (bvsalud.org)
- On the other hand, in our country, cow's milk is one of the major allergens in paediatric patients, and even though its exclusion from the diet is extremely difficult due to its wide distribution in food products and its nutritional importance in feeding the child, researches that address the problems related to this restriction are still lacking. (bvsalud.org)
- The most accepted hypothesis is that it may be caused by allergic hypersensitivity to certain foods (like nuts and milk), air pollution or chemical components present in the modern industrialized foods and oral hygienic products. (sciencedaily.com)
Immune response6
- The Gell and Coombs classification of hypersensitivity is the most widely used, and distinguishes four types of immune response which result in bystander tissue damage. (wikipedia.org)
- Food allergy is an exaggerated immune response to dietary components, usually proteins. (msdmanuals.com)
- However, since every food we eat contains proteins that are foreign to the body, it would be inefficient for the body to create a full immune response every time we eat. (purehealthsystems.com)
- In normal, healthy individuals the GALT system responds to ingested invaders to protect the individual and will elicit an immune response against the invader, but will not elicit an immune response to ingested food proteins. (purehealthsystems.com)
- However, in individuals with food allergies, the GALT system will respond to particular food proteins as invaders and will elicit a full immune response against the ingested food protein. (purehealthsystems.com)
- Brinkman et al5 examined whether the presence and foods.1,2 However, much less is known about the poten- severity of AD was predictive of the occurrence and mag- tial influence that skin challenges have on the systemic nitude of early and late asthmatic responses to inhaled immune response, in particular whether sensitization allergens. (cdc.gov)
Adverse3
- Position paper: Adverse reactions to food. (aerzteblatt.de)
- But contrary to popular belief, not all of these adverse reactions are food allergies. (purehealthsystems.com)
- Temporary dietary restrictions designed to help identify specific foods or FOOD ADDITIVES that trigger ALLERGIC REACTIONS, symptoms of DIGESTIVE SYSTEM DISORDERS, or other adverse food reactions. (bvsalud.org)
Additives1
- and reactions to additives (eg, monosodium glutamate, metabisulfite, tartrazine) or food contaminants (eg, latex dust in food handled by workers wearing latex gloves). (msdmanuals.com)
Hyperplasia1
- Colonic lymphoid nodular hyperplasia in children: relationship to food hypersensitivity. (aerzteblatt.de)
Respiratory4
- Health hazard evaluation report: evaluation of respiratory concerns at a snack food production facility, New York. (cdc.gov)
- Food or digestive allergies, skin allergies (such as eczema), and respiratory allergies (such as hay fever) are the most common allergies among children. (cdc.gov)
- Hispanic children had a lower prevalence of food allergy, skin allergy, and respiratory allergy compared with children of other race or ethnicities. (cdc.gov)
- Food and respiratory allergy prevalence increased with income level. (cdc.gov)
Wheat1
- Moneret Vautrin DA, Sainte-Laudy J, Kanny G: Ulcerative colitis possibly due to hypersensitivity to wheat and egg. (aerzteblatt.de)
Abnormal1
- Food allergy is an abnormal response to a food triggered by your body's immune system. (medlineplus.gov)
Disorders1
- The pet food industry relies on recommendations by the National Research Council to prevent diseases caused by nutrient deficiencies in the "average" pet, yet the NRC has not determined the optimum amount of nutrients or their effects in treating medical disorders. (totalhealthmagazine.com)
Infections3
- Type IV hypersensitivity reactions are, to some extent, normal physiological events that help fight infections, and dysfunction in this system can predispose to multiple opportunistic infections. (wikipedia.org)
- Many diseases and infections, including cancer and certain viral infections (especially HIV infection), and some immunosuppressive drugs may result in a transient or continuing suppression of cellular hypersensitivity mediated by T-lymphocytes. (cdc.gov)
- Some dermatologists believe that up to 50% of ear infections in cats are due to food allergies, but only 15% of similar infections in dogs. (onlynaturalpet.com)
Occur5
- Encourage avoidance of high-risk situations (eg, buffets, picnics) where accidental or inadvertent ingestion of food allergens can occur. (medscape.com)
- Despite following stringent avoidance measures for clinically relevant food allergens, accidental or inadvertent ingestions may occur. (medscape.com)
- The first three types are considered immediate hypersensitivity reactions because they occur within 24 hours. (wikipedia.org)
- Cross-reactivity between food and nonfood allergens exists, and sensitization may occur nonenterally. (msdmanuals.com)
- Food allergies are relatively rare and occur in only 6% of children under 3 years of age and in 1.4% of adults. (purehealthsystems.com)
Anaphylactic1
- Further fatalities caused by anaphylactic reactions to food, 2001-2006. (medscape.com)
Antigens3
- In 1963, Philip George Houthem Gell and Robin Coombs introduced a systematic classification of the different types of hypersensitivity based on the types of antigens and immune responses involved. (wikipedia.org)
- The Food and Drug Administration has licensed for the evaluation of cellular hypersensitivity a multiple puncture device (MULTITEST CMI(R)) that delivers seven DTH antigens percutaneously. (cdc.gov)
- In contrast, responses to antigens administered by a Mantoux-type procedure, in which a known quantity of a known concentration of a standardized antigen is deposited in the skin, may be more accurate indicators of a waning or increasing cellular hypersensitivity. (cdc.gov)
Diet8
- Your health care provider may use a detailed history, elimination diet, and skin and blood tests to diagnose a food allergy. (medlineplus.gov)
- After you and your health care provider have identified the foods to which you are sensitive, you must remove them from your diet. (medlineplus.gov)
- Food Consumption Patterns in a Mediterranean Region: Does the Mediterranean Diet Still Exist? (karger.com)
- If you are following a TRUE Gluten free diet and still not feeling your best, food sensitivities might be responsible. (glutenfreesociety.org)
- Your body's response to certain foods, paired with a temporary elimination diet, may help you determine the cause of your physical symptoms. (glutenfreesociety.org)
- In addition to breast-feeding, the mother can help by delaying the introduction of solid foods into the child's diet and specifically by delaying the introduction of common allergenic foods. (purehealthsystems.com)
- The initial approach to orthomolecular therapies involves a hypoallergenic diet free of by-products, chemical preservatives, fillers, and artificial colorings and flavorings to decrease potential hypersensitivity within the gastrointestinal tract. (totalhealthmagazine.com)
- While it is true the pancreas produces enzymes to aid in food digestion, additional enzymes found in the diet contribute to digestion and absorption as well and may enhance food efficiency. (totalhealthmagazine.com)
Therapy1
- I am a member of the UK Food Safety Research Network and also the life member of Society For Bacteriophage Research and Therapy, India. (nottingham.ac.uk)
Prevalence1
- Among children aged 0-17 years, the prevalence of food allergies increased from 3.4% in 1997-1999 to 5.1% in 2009-2011. (cdc.gov)
Sensitivities1
- Evaluation and treatment of Martin's inhalant and food sensitivities resulted in a major improvement so that he was able to benefit more from his school program and participate in family activities that would have previously been impossible. (directlabs.com)
Symptoms of food allergy1
- You can only prevent the symptoms of food allergy by avoiding the food. (medlineplus.gov)
Parents have food allergies1
- However, just because your parents have food allergies, does not absolutely mean you will develop a food allergy. (purehealthsystems.com)
Diseases1
- Aiuti F, Paganelli R: Food allergy and gastrointestinal diseases. (aerzteblatt.de)
Types1
- There are four types of hypersensitivity reactions, but most of the allergies our pets are prone to are Type I or "immediate" hypersensitivity. (onlynaturalpet.com)
True food allergies2
- Reactions that do not involve the immune system are food intolerances and are not true food allergies. (purehealthsystems.com)
- Because they involve antibodies and immune-based inflammation, true food allergies are very different from dietary intolerances. (onlynaturalpet.com)
Children1
- Most children with his kinds of problems - and including children with all sorts of attention problems - have hypersensitivity to foods, and inhalants. (directlabs.com)
Skin1
- Food sensitization at 1 year was determined by skin prick testing in 166 infants from the population-based Canadian Healthy Infant Longitudinal Development (CHILD) study. (nih.gov)
Proteins2
- These nonallergenic reactions are thought to be much more common than food allergies, and can be caused by toxic, pharmacologic, metabolic, or idiosyncratic reactions to chemical substances and proteins in foods. (purehealthsystems.com)
- As a result the body has developed an "oral tolerance" that exists only in the gut and prevents the immune system from hyper-responding to foreign proteins in foods. (purehealthsystems.com)
Veterinary3
- I am a faculty at the School of Veterinary Medicine and Science, University of Nottingham, UK and prior to this I was with the Canadian Food Inspection Agency and with the Food Safety and Quality Program at McGill University, Montreal, Canada. (nottingham.ac.uk)
- I have a longstanding track record of excellence in food safety research and Veterinary Public Health (VPH) teaching internationally. (nottingham.ac.uk)
- I also have taught food safety and public health courses in various Veterinary schools in India and in my defence job in India I was associated with procurement and inspection of meat supplied to the troops. (nottingham.ac.uk)
Intolerances1
- Food allergies are much less common than food intolerances. (onlynaturalpet.com)
Evaluation1
- In December 2010, the National Institute for Occupational Safety and Health (NIOSH) received a confidential employee request for a health hazard evaluation (HHE) at a snack food production facility in New York. (cdc.gov)
Exposure2
- When you have food allergies, you must be prepared to treat an accidental exposure. (medlineplus.gov)
- Type I hypersensitivity occurs as a result of exposure to an antigen. (wikipedia.org)
Clinical2
- Clinical implications of cross-reactive food allergens. (medscape.com)
- The experimental model described here reproduces the clinical and pathological changes of mild chronic food allergy and may be useful for mechanistic studies of this common clinical condition. (bvsalud.org)
Severe1
- In severe cases, the patients may need to undergo a procedure to dilate the esophagus to let the food pass. (sciencedaily.com)