Sleep Deprivation
Feeding Behavior
Obsessive Hoarding
Phodopus
Sensory Deprivation
Hypothalamus
Body Weight
Seals, Earless
Psychosocial Deprivation
Energy Metabolism
Food Labeling
Rats, Sprague-Dawley
Leptin
Rats, Wistar
Arcuate Nucleus
Corticosterone
Ventromedial Hypothalamic Nucleus
RNA, Messenger
Appetite
Food Industry
Receptors, Neuropeptide
Food Microbiology
Cultural Deprivation
Neuropeptide Y
Ghrelin
Food Hypersensitivity
Liver
Neuropeptides
Conditioning, Operant
Health Food
Food Contamination
Adipose Tissue
Food Handling
Food Safety
Analysis of Variance
Fast Foods
Glucose
Obesity
Dietary Fats
Rats, Zucker
Fatty Acids, Nonesterified
Muscle, Skeletal
Muscle Fibers, Fast-Twitch
Food, Fortified
Insulin
Reinforcement Schedule
Food, Genetically Modified
Circadian Rhythm
Food Chain
Stress, Physiological
Food Services
Lactation
Random Allocation
Lipid Metabolism
Poverty Areas
Gene Expression Regulation
Signal Transduction
Motivation
Neurons
Brain
Body Composition
Modulation of estrogen action in the rat pituitary and mammary glands by dietary energy consumption. (1/1450)
We are investigating the mechanisms through which estrogens induce development of prolactin (PRL)-producing pituitary tumors and mammary carcinomas in rats and how these mechanisms are affected by dietary energy consumption. The hypothesis under examination is that dietary energy restriction inhibits tumorigenesis in estrogen-responsive tissues by altering cellular responsiveness to estrogenic hormones. In the Fischer 344 (F344) rat strain, a 40% restriction of energy consumption virtually abolishes development of estrogen-induced pituitary tumors. Inhibition of pituitary tumorigenesis in the F344 strain by energy restriction results from modulation of estrogen regulation of cell survival, not cell proliferation. In contrast, energy restriction has no inhibitory effect on estrogen-induced pituitary tumor development in the ACI rat strain. However, energy restriction markedly inhibits induction of mammary carcinomas in female ACI rats treated with 17beta-estradiol. Data presented herein indicate that dietary energy restriction modulates the responsiveness of specific cell populations to estrogenic hormones and thereby inhibits estrogen-induced tumorigenesis in a manner specific to both rat strain and tissue. (+info)Lateral hypothalamic NMDA receptor subunits NR2A and/or NR2B mediate eating: immunochemical/behavioral evidence. (2/1450)
Cells within the lateral hypothalamic area (LHA) are important in eating control. Glutamate or its analogs, kainic acid (KA) and N-methyl-D-aspartate (NMDA), elicit intense eating when microinjected there, and, conversely, LHA-administered NMDA receptor antagonists suppress deprivation- and NMDA-elicited eating. The subunit composition of LHA NMDA receptors (NMDA-Rs) mediating feeding, however, has not yet been determined. Identifying this is important, because distinct second messengers/modulators may be activated by NMDA-Rs with differing compositions. To begin to address this, we detected LHA NR2A and NR2B subunits by immunoblotting and NR2B subunits by immunohistochemistry using subunit-specific antibodies. To help determine whether NMDA-Rs mediating feeding might contain these subunits, we conducted behavioral studies using LHA-administered ifenprodil, an antagonist selective for NR2A- and/or NR2B-containing NMDA-Rs at the doses we used (0.001-100 nmol). Ifenprodil maximally suppressed NMDA- and deprivation-elicited feeding by 63 and 39%, respectively, but failed to suppress KA-elicited eating, suggesting its actions were behaviorally specific. Collectively, these results suggest that LHA NMDA-Rs, some of which contribute to feeding control, are composed of NR2A and/or NR2B subunits, and implicate NR2A- and/or NR2B-linked signal transduction in feeding behavior. (+info)Effect of long-term food restriction on pituitary sensitivity to cLHRH-I in broiler breeder females. (3/1450)
The effect of long-term food restriction on the sensitivity of the pituitary to exogenously administered chicken luteinizing hormone releasing hormone I (cLHRH-I) was investigated in three groups of broiler breeder females fed ad libitum, fed a restricted quantity of food or fed a restricted quantity of food to obtain an intermediate body weight between those of the first two groups. At 16 weeks of age, basal FSH release was higher in ad libitum fed birds, culminating in ovarian development and subsequent oestradiol production by the small follicles. At this age, LH secretion was independent of ovarian feedback factors. In all groups, cLHRH-I was most active in releasing LH in intact and ovariectomized animals and, to a lesser extent, in releasing FSH in ovariectomized birds. At 39 weeks of age, basal FSH concentrations were similar among intact animals of all groups, whereas LH concentrations differed among groups, with higher values in the restricted birds. This food effect was enhanced in ovariectomized birds. Furthermore, the high response to cLHRH-I in the ovariectomized, restricted birds compared with the ad libitum, ovariectomized group suggests an improved sensitivity of the hypothalamic-pituitary axis. In conclusion, birds fed ad libitum showed the highest responsiveness to ovarian factors and to cLHRH-I in releasing FSH in the period before sexual maturity. No effect of amount of feeding could be observed for LH. However, during the egg laying period, LH release by cLHRH-I was highly dependent on amount of feeding and on ovarian feedback regulation. This finding indicates that the amount of feeding can modify the sensitivity of the pituitary to cLHRH-I, and possibly to gonadal hormones, during the laying period. (+info)Expression of T lymphocyte p56(lck), a zinc-finger signal transduction protein, is elevated by dietary zinc deficiency and diet restriction in mice. (4/1450)
Compromised immune function is common to Zn deficiency, protein and energy malnutrition; however, the causative mechanisms at the molecular level have not been elucidated. The T lymphocyte signal transduction pathway contains several Zn-finger proteins, and it is possible that the in vivo functioning of these proteins could be affected by dietary deficiency of Zn and amino acids. Thus, the objective was to investigate the effects, on expression of the T lymphocyte signal transduction proteins p56(lck), phospholipase Cgamma1 (PLCgamma1) and protein kinase C (PKCalpha), of dietary Zn deficiency (ZnDF, < 1 mg Zn/kg diet) and protein-energy malnutrition syndromes [2% protein deficiency (LP), combined Zn and 2% protein deficiency (ZnDF+LP), and diet restriction (DR, body weight equal to ZnDF)] compared with control (C) mice. Indices of nutritional status and splenocyte counts were also determined. Based on serum albumin and liver lipid concentrations, the ZnDF+LP and LP groups had protein-type malnutrition, whereas the ZnDF and DR groups had energy-type malnutrition. For Western immunoblotting of the signal transduction proteins, mouse splenic T lymphocytes were isolated by immunocolumns. The expression of T lymphocyte p56(lck) was significantly elevated in the ZnDF+LP, ZnDF and DR groups compared to the C group. In contrast, the expression of PLCgamma1 and PKC was unaffected. There was a significant negative correlation between T lymphocyte p56(lck) expression and serum Zn (r= -0.65, P = 0.0007) or femur Zn (r = -0.73, P = 0.0001) concentrations. We propose that elevated T lymphocyte p56(lck) may contribute to altered thymoctye maturation, apoptosis and lymphopenia in Zn deficiency and protein-energy malnutrition syndromes. (+info)Interaction between genetic and dietary factors determines beta-cell function in Psammomys obesus, an animal model of type 2 diabetes. (5/1450)
The gerbil Psammomys obesus develops nutrition-dependent diabetes. We studied the interaction between diet and diabetic predisposition for beta-cell function. A 4-day high-energy (HE) diet induced a 3-, 4-, and 1.5-fold increase in serum glucose, insulin, and triglycerides, respectively, in diabetes-prone (DP) but not diabetes-resistant (DR) P. obesus. Hyperglycemia and concurrent 90% depletion of islet immunoreactive insulin stores were partially corrected by an 18-h fast. In vitro early insulin response to glucose was blunted in both DR and DP perifused islets. The HE diet augmented early and late insulin response in DR islets, whereas in DP islets, secretion progressively declined. Dose-response studies showed a species-related increase in islet glucose sensitivity, further augmented in DP P. obesus by a HE diet, concomitant with a decreased threshold for glucose and a 55% reduction in maximal response. These changes were associated with a fourfold increase in glucose phosphorylation capacity in DP islets. There were no differences in islet glucokinase (GK) and hexokinase (HK) Km; however, GK Vmax was 3.7- to 4.6-fold higher in DP islets, and HK Vmax was augmented 3.7-fold by the HE diet in DP islets. We conclude that the insulin-resistant P. obesus has an inherent deficiency in insulin release. In the genetically predisposed P. obesus (DP), augmented islet glucose phosphorylation ability and diet-induced reduction of the glucose threshold for secretion may lead to inadequate insulin secretion and depletion of insulin stores in the presence of caloric abundance. Thus, genetic predisposition and beta-cell maladaptation to nutritional load seem to determine together the progression to overt diabetes in this species. It is hypothesized that similar events may occur in obese type 2 diabetic patients. (+info)Phosphate depletion in the rat: effect of bisphosphonates and the calcemic response to PTH. (6/1450)
BACKGROUND: The removal of phosphate from the diet of the growing rat rapidly produces hypercalcemia, hypophosphatemia, hypercalciuria, and hypophosphaturia. Increased calcium efflux from bone has been shown to be the important cause of the hypercalcemia and hypercalciuria. It has been proposed that the increased calcium efflux from bone is osteoclast mediated. Because bisphosphonates have been shown to inhibit osteoclast-mediated bone resorption, this study was performed to determine whether bisphosphonate-induced inhibition of osteoclast function changed the biochemical and bone effects induced by phosphate depletion. METHODS: Four groups of pair-fed rats were studied: (a) low-phosphate diet (LPD; phosphate less than 0.05%), (b) LPD plus the administration of the bisphosphonate Pamidronate (APD; LPD + APD), (c) normal diet (ND, 0.6% phosphate), and (d) ND + APD. All diets contained 0.6% calcium. A high dose of APD was administered subcutaneously (0.8 mg/kg) two days before the start of the study diet and on days 2, 6, and 9 during the 11 days of the study diet. On day 10, a 24-hour urine was collected, and on day 11, rats were either sacrificed or received an additional APD dose before a 48-hour parathyroid hormone (PTH) infusion (0.066 microgram/100 g/hr) via a subcutaneously implanted miniosmotic pump. RESULTS: Serum and urinary calcium were greater in the LPD and LPD + APD groups than in the ND and ND + APD groups [serum, 11.12 +/- 0.34 and 11.57 +/- 0.45 vs. 9.49 +/- 0.17 and 9.48 +/- 0.15 mg/dl (mean +/- SE), P < 0.05; and urine, 8.78 +/- 2.74 and 16.30 +/- 4.68 vs. 0.32 +/- 0.09 and 0.67 +/- 0.28 mg/24 hr, P < 0.05]. Serum PTH and serum and urinary phosphorus were less in the LPD and LPD + APD than in the ND and ND + APD groups (P < 0.05). The calcemic response to PTH was less (P < 0.05) in the LPD and LPD + APD groups than in the ND group and was less (P = 0.05) in the LPD + APD than in the ND + APD group. Bone histology showed that phosphate depletion increased the osteoblast and osteoclast surface, and treatment with APD reduced the osteoblast surface (LPD vs. LPD + APD, 38 +/- 4 vs. 4 +/- 2%, P < 0.05, and ND vs. ND + APD, 20 +/- 2 vs. 5 +/- 2%, P < 0.05) and markedly altered osteoclast morphology by inducing cytoplasmic vacuoles. CONCLUSIONS: (a) Phosphate depletion induced hypercalcemia and hypercalciuria that were not reduced by APD administration. (b) The calcemic response to PTH was reduced in phosphate-depleted rats and was unaffected by APD administration in normal and phosphate-depleted rats, and (c) APD administration markedly changed bone histology without affecting the biochemical changes induced by phosphate depletion. (+info)Growth hormone promotes somatic and skeletal muscle growth recovery in rats following chronic protein-energy malnutrition. (7/1450)
The efficacy of recombinant human growth hormone (GH) and/or a diet enriched in protein and energy to improve growth recovery following prolonged malnutrition was examined in male rats food-restricted from birth until 120 d of age. At d 121, restricted rats were randomly assigned to recovery groups receiving either a control or enriched diet with or without daily subcutaneous injections of GH. Rats were killed after 16 or 47 d of recovery. At d 16, GH treatment stimulated liver, heart, plantaris, soleus, carcass and body weight gain and inhibited fat gain when compared to recovery controls. Rats receiving GH also exhibited the highest serum insulin-like growth factor-I (IGF-I) concentrations and total muscle protein. At d 47, GH effects on body and muscle recovery were minimal, and differences among recovery groups in serum IGF-I concentration and total muscle protein were no longer present. Consumption of an enriched diet increased fat pad and liver mass, but did not promote muscle recovery. There were no differences among treatment groups in skeletal muscle IGF-I mRNA levels at d 16 or 47. In summary, GH had positive effects on somatic and skeletal muscle growth early in the recovery process, possibly via endocrine IGF-I-stimulated protein accretion. In contrast, the enriched diet promoted fat deposition with no impact on skeletal muscle growth recovery. (+info)Feed deprivation affects crop environment and modulates Salmonella enteritidis colonization and invasion of leghorn hens. (8/1450)
Leghorn hens over 50 weeks of age were assigned to two treatment groups designated as either unmolted controls or molted. A forced molt was induced by a 9-day feed withdrawal, and each hen was challenged orally with 10(5) Salmonella enteritidis organisms on day 4 of feed withdrawal. On days 4 and 9 of molt, the numbers of lactobacilli and the concentrations of lactate, acetate, propionate, and butyrate, and total volatile fatty acids in the crops decreased while crop pH increased significantly (P < 0.05) in the molted hens compared to the controls. S. enteritidis crop and cecal colonization, in addition to spleen and liver invasion, increased significantly (P < 0.05) in the molted hens compared to the controls. The invasive phenotype of Salmonella spp. is complex and requires several virulence genes which are regulated by the transcriptional activator HilA. Samples of the crop contents from the molted and unmolted birds were pooled separately, centrifuged, and filter sterilized. The sterile crop contents were then used to measure the expression of hilA. By using a lacZY transcriptional fusion to the hilA gene in S. enteritidis, we found that hilA expression was 1.6- to 2.1-fold higher in the crop contents from molted birds than in those from control birds in vitro. The results of the study suggest that the changes in the microenvironment of the crop caused by feed deprivation are important regulators of S. enteritidis survival and influence the susceptibility of molted hens to S. enteritidis infections. Furthermore, our in vitro results on the expression of hilA suggest that the change in crop environment during feed withdrawal has the potential to significantly affect virulence by increasing the expression of genes necessary for intestinal invasion. (+info)The effects of sleep deprivation can be severe and long-lasting, including:
1. Impaired cognitive function: Sleep deprivation can affect attention, memory, and decision-making skills, making it more difficult to perform daily tasks and make sound judgments.
2. Emotional distress: Lack of sleep can lead to irritability, anxiety, and depression, which can negatively impact relationships and overall well-being.
3. Physical health problems: Chronic sleep deprivation has been linked to an increased risk of obesity, diabetes, cardiovascular disease, and immune system dysfunction.
4. Impaired motor function: Sleep deprivation can cause coordination problems, clumsiness, and a higher risk of accidents, particularly in activities that require attention and quick reflexes (e.g., driving).
5. Premature aging: Chronic sleep deprivation can accelerate the aging process and reduce the body's ability to repair and regenerate cells.
6. Reduced productivity and performance: Sleep deprivation can lead to decreased productivity, poor work quality, and increased absenteeism, which can negatively impact career advancement and financial stability.
7. Increased risk of accidents and injuries: Drowsy driving and workplace accidents are common consequences of sleep deprivation, which can result in fatalities and long-term disabilities.
8. Weakened immune system: Sleep deprivation can weaken the immune system, making it more difficult to fight off infections and diseases.
9. Negative impact on relationships: Sleep deprivation can lead to mood swings, irritability, and difficulty interacting with others, which can strain personal and professional relationships.
10. Increased risk of mental health disorders: Chronic sleep deprivation has been linked to an increased risk of developing anxiety, depression, and other mental health disorders.
To avoid these negative consequences, it's essential to prioritize sleep and make it a critical component of your daily routine. Establishing a consistent sleep schedule, creating a sleep-conducive environment, and practicing relaxation techniques can help improve sleep quality and duration. Additionally, avoiding stimulating activities before bedtime, limiting exposure to electronic screens, and seeking professional help if sleep problems persist can contribute to better overall health and well-being.
The criteria for obsessive hoarding include:
1. Persistent difficulty discarding or parting with possessions, regardless of their actual value.
2. The difficulty is due to a perceived need to save the items and not to a desire to collect them.
3. The difficulty leads to cluttered living spaces that are difficult to use for their intended purpose.
4. The difficulty significantly interferes with daily functioning or causes significant distress.
5. The difficulty is not better explained by another mental disorder, such as obsessive-compulsive disorder (OCD) or attention deficit hyperactivity disorder (ADHD).
6. The hoarding behavior is not better accounted for by another mental disorder, such as delusional disorder or obsessive-compulsive personality disorder.
The exact cause of obsessive hoarding is not yet fully understood, but it is thought to be a complex interplay of biological, psychological, and environmental factors. Some research suggests that hoarding may be related to abnormalities in brain regions involved in decision-making, emotional regulation, and executive functioning. Additionally, obsessive hoarding may be associated with other mental health conditions, such as anxiety disorders and depression.
Treatment for obsessive hoarding typically involves a combination of cognitive-behavioral therapy (CBT) and professional organizing. CBT can help individuals understand the underlying causes of their hoarding behavior and learn strategies to manage it, while professional organizing can help individuals develop the skills and resources needed to declutter their living spaces. In some cases, medication may also be prescribed to help manage symptoms such as anxiety or depression.
Starvation is a condition where an individual's body does not receive enough nutrients to maintain proper bodily functions and growth. It can be caused by a lack of access to food, poverty, poor nutrition, or other factors that prevent the intake of sufficient calories and essential nutrients. Starvation can lead to severe health consequences, including weight loss, weakness, fatigue, and even death.
Types of Starvation:
There are several types of starvation, each with different causes and effects. These include:
1. Acute starvation: This occurs when an individual suddenly stops eating or has a limited access to food for a short period of time.
2. Chronic starvation: This occurs when an individual consistently does not consume enough calories and nutrients over a longer period of time, leading to gradual weight loss and other health problems.
3. Malnutrition starvation: This occurs when an individual's diet is deficient in essential nutrients, leading to malnutrition and other health problems.
4. Marasmus: This is a severe form of starvation that occurs in children, characterized by extreme weight loss, weakness, and wasting of muscles and organs.
5. Kwashiorkor: This is a form of malnutrition caused by a diet lacking in protein, leading to edema, diarrhea, and other health problems.
Effects of Starvation on the Body:
Starvation can have severe effects on the body, including:
1. Weight loss: Starvation causes weight loss, which can lead to a decrease in muscle mass and a loss of essential nutrients.
2. Fatigue: Starvation can cause fatigue, weakness, and a lack of energy, making it difficult to perform daily activities.
3. Weakened immune system: Starvation can weaken the immune system, making an individual more susceptible to illnesses and infections.
4. Nutrient deficiencies: Starvation can lead to a deficiency of essential nutrients, including vitamins and minerals, which can cause a range of health problems.
5. Increased risk of disease: Starvation can increase the risk of diseases such as tuberculosis, pellagra, and other infections.
6. Mental health issues: Starvation can lead to mental health issues such as depression, anxiety, and irritability.
7. Reproductive problems: Starvation can cause reproductive problems, including infertility and miscarriage.
8. Hair loss: Starvation can cause hair loss, which can be a sign of malnutrition.
9. Skin problems: Starvation can cause skin problems, such as dryness, irritation, and infections.
10. Increased risk of death: Starvation can lead to increased risk of death, especially in children and the elderly.
It is important to note that these effects can be reversed with proper nutrition and care. If you or someone you know is experiencing starvation, it is essential to seek medical attention immediately.
Body weight is an important health indicator, as it can affect an individual's risk for certain medical conditions, such as obesity, diabetes, and cardiovascular disease. Maintaining a healthy body weight is essential for overall health and well-being, and there are many ways to do so, including a balanced diet, regular exercise, and other lifestyle changes.
There are several ways to measure body weight, including:
1. Scale: This is the most common method of measuring body weight, and it involves standing on a scale that displays the individual's weight in kg or lb.
2. Body fat calipers: These are used to measure body fat percentage by pinching the skin at specific points on the body.
3. Skinfold measurements: This method involves measuring the thickness of the skin folds at specific points on the body to estimate body fat percentage.
4. Bioelectrical impedance analysis (BIA): This is a non-invasive method that uses electrical impulses to measure body fat percentage.
5. Dual-energy X-ray absorptiometry (DXA): This is a more accurate method of measuring body composition, including bone density and body fat percentage.
It's important to note that body weight can fluctuate throughout the day due to factors such as water retention, so it's best to measure body weight at the same time each day for the most accurate results. Additionally, it's important to use a reliable scale or measuring tool to ensure accurate measurements.
There are several types of food hypersensitivity, including:
1. Food Allergy: An immune system reaction to a specific food that can cause symptoms ranging from mild hives to life-threatening anaphylaxis. Common food allergies include reactions to peanuts, tree nuts, fish, shellfish, milk, eggs, wheat, and soy.
2. Non-Allergic Food Hypersensitivity: Also known as non-IgE-mediated food hypersensitivity, this type of reaction does not involve the immune system. Symptoms can include bloating, abdominal pain, diarrhea, and headaches. Common culprits include gluten, dairy, and high-FODMAP foods.
3. Food Intolerance: A condition where the body cannot properly digest or process a specific food. Symptoms can include bloating, abdominal pain, diarrhea, and gas. Common food intolerances include lactose intolerance, fructose malabsorption, and celiac disease.
4. Food Aversion: An emotional response to a specific food that can cause avoidance or dislike of the food. This is not an allergic or physiological reaction but rather a psychological one.
The diagnosis of food hypersensitivity typically involves a thorough medical history, physical examination, and diagnostic tests such as skin prick testing or blood tests. Treatment options for food hypersensitivity depend on the type and severity of the reaction and may include avoidance of the offending food, medication, or immunotherapy.
There are several different types of obesity, including:
1. Central obesity: This type of obesity is characterized by excess fat around the waistline, which can increase the risk of health problems such as type 2 diabetes and cardiovascular disease.
2. Peripheral obesity: This type of obesity is characterized by excess fat in the hips, thighs, and arms.
3. Visceral obesity: This type of obesity is characterized by excess fat around the internal organs in the abdominal cavity.
4. Mixed obesity: This type of obesity is characterized by both central and peripheral obesity.
Obesity can be caused by a variety of factors, including genetics, lack of physical activity, poor diet, sleep deprivation, and certain medications. Treatment for obesity typically involves a combination of lifestyle changes, such as increased physical activity and a healthy diet, and in some cases, medication or surgery may be necessary to achieve weight loss.
Preventing obesity is important for overall health and well-being, and can be achieved through a variety of strategies, including:
1. Eating a healthy, balanced diet that is low in added sugars, saturated fats, and refined carbohydrates.
2. Engaging in regular physical activity, such as walking, jogging, or swimming.
3. Getting enough sleep each night.
4. Managing stress levels through relaxation techniques, such as meditation or deep breathing.
5. Avoiding excessive alcohol consumption and quitting smoking.
6. Monitoring weight and body mass index (BMI) on a regular basis to identify any changes or potential health risks.
7. Seeking professional help from a healthcare provider or registered dietitian for personalized guidance on weight management and healthy lifestyle choices.
There are several different types of weight gain, including:
1. Clinical obesity: This is defined as a BMI of 30 or higher, and is typically associated with a range of serious health problems, such as heart disease, type 2 diabetes, and certain types of cancer.
2. Central obesity: This refers to excess fat around the waistline, which can increase the risk of health problems such as heart disease and type 2 diabetes.
3. Muscle gain: This occurs when an individual gains weight due to an increase in muscle mass, rather than fat. This type of weight gain is generally considered healthy and can improve overall fitness and athletic performance.
4. Fat gain: This occurs when an individual gains weight due to an increase in body fat, rather than muscle or bone density. Fat gain can increase the risk of health problems such as heart disease and type 2 diabetes.
Weight gain can be measured using a variety of methods, including:
1. Body mass index (BMI): This is a widely used measure of weight gain that compares an individual's weight to their height. A BMI of 18.5-24.9 is considered normal, while a BMI of 25-29.9 is considered overweight, and a BMI of 30 or higher is considered obese.
2. Waist circumference: This measures the distance around an individual's waistline and can be used to assess central obesity.
3. Skinfold measurements: These involve measuring the thickness of fat at specific points on the body, such as the abdomen or thighs.
4. Dual-energy X-ray absorptiometry (DXA): This is a non-invasive test that uses X-rays to measure bone density and body composition.
5. Bioelectrical impedance analysis (BIA): This is a non-invasive test that uses electrical impulses to measure body fat percentage and other physiological parameters.
Causes of weight gain:
1. Poor diet: Consuming high amounts of processed foods, sugar, and saturated fats can lead to weight gain.
2. Lack of physical activity: Engaging in regular exercise can help burn calories and maintain a healthy weight.
3. Genetics: An individual's genetic makeup can affect their metabolism and body composition, making them more prone to weight gain.
4. Hormonal imbalances: Imbalances in hormones such as insulin, thyroid, and cortisol can contribute to weight gain.
5. Medications: Certain medications, such as steroids and antidepressants, can cause weight gain as a side effect.
6. Sleep deprivation: Lack of sleep can disrupt hormones that regulate appetite and metabolism, leading to weight gain.
7. Stress: Chronic stress can lead to emotional eating and weight gain.
8. Age: Metabolism slows down with age, making it more difficult to maintain a healthy weight.
9. Medical conditions: Certain medical conditions such as hypothyroidism, Cushing's syndrome, and polycystic ovary syndrome (PCOS) can also contribute to weight gain.
Treatment options for obesity:
1. Lifestyle modifications: A combination of diet, exercise, and stress management techniques can help individuals achieve and maintain a healthy weight.
2. Medications: Prescription medications such as orlistat, phentermine-topiramate, and liraglutide can aid in weight loss.
3. Bariatric surgery: Surgical procedures such as gastric bypass surgery and sleeve gastrectomy can be effective for severe obesity.
4. Behavioral therapy: Cognitive-behavioral therapy (CBT) and other forms of counseling can help individuals develop healthy eating habits and improve their physical activity levels.
5. Meal replacement plans: Meal replacement plans such as Medifast can provide individuals with a structured diet that is high in protein, fiber, and vitamins, and low in calories and sugar.
6. Weight loss supplements: Supplements such as green tea extract, garcinia cambogia, and forskolin can help boost weight loss efforts.
7. Portion control: Using smaller plates and measuring cups can help individuals regulate their portion sizes and maintain a healthy weight.
8. Mindful eating: Paying attention to hunger and fullness cues, eating slowly, and savoring food can help individuals develop healthy eating habits.
9. Physical activity: Engaging in regular physical activity such as walking, running, swimming, or cycling can help individuals burn calories and maintain a healthy weight.
It's important to note that there is no one-size-fits-all approach to treating obesity, and the most effective treatment plan will depend on the individual's specific needs and circumstances. Consulting with a healthcare professional such as a registered dietitian or a physician can help individuals develop a personalized treatment plan that is safe and effective.
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Link Between Sleep Deprivation2
- Is There A Link Between Sleep Deprivation and Weight Gain? (goqii.com)
- If you or someone you love is having trouble sleeping or struggling with symptoms of depression, you likely already have an intimate understanding of the link between sleep deprivation and depression . (verywellhealth.com)
Insecurity8
- These areas were characterized by larger proportions of Hispanic and non-White residents, persons working in manual, essential, and public-facing sectors, more crowded housing, and food and health care insecurity. (cdc.gov)
- The dietitian deems it inappropriate to make an opportunistic brief intervention on food insecurity. (who.int)
- INTRODUCTION: A healthy diet is recommended to support diabetes management, including HbA1c, blood pressure, and cholesterol (ABC) control, but food insecurity is a barrier to consuming a healthy diet. (cdc.gov)
- We determined the prevalence of food insecurity and diet quality among US adults with diabetes and the associations with ABC management. (cdc.gov)
- Food insecurity was assessed using a standard questionnaire and diet quality was assessed using quartiles of the 2015 Healthy Eating Index. (cdc.gov)
- Adjusted ORs (aOR, 95% CI) were calculated from logistic regression models to determine the association between household food insecurity/diet quality and the ABCs while controlling for sociodemographic characteristics, healthcare utilization, smoking, medication for diabetes, blood pressure, or cholesterol, and body mass index. (cdc.gov)
- CONCLUSIONS: Food insecurity, regardless of diet quality, was significantly associated with elevated A1c. (cdc.gov)
- For people with food insecurity, providing resources to reduce food insecurity could strengthen the overall approach to optimal diabetes management. (cdc.gov)
Cravings1
- Aside from making your mind less sharp and generally making you feel crappy, a new study demonstrates another unsavory effect of sleep deprivation: It could actually spur junk food cravings, similar to those induced by marijuana. (glamour.com)
Significantly4
- Published in The Journal of Allergy and Clinical Immunology, the team found that exercise and sleep deprivation each significantly reduce the threshold of reactivity (the amount of peanut needed to trigger a reaction) in people with peanut allergy, putting them at greater risk of a reaction. (food.gov.uk)
- The work, which could be applied to other foods, reveals that exercise, sleep deprivation or stress significantly reduce the amount of peanut required to cause an allergic reaction. (food.gov.uk)
- Sleep-deprived men purchased significantly more calories (+9%) and grams (+18%) of food than they did after one night of sleep. (goqii.com)
- Results from the study show that sleep deprivation significantly decreased activity in appetitive evaluation regions within the brain during food desirability choices, combined with increased activity in the amygdala. (goqii.com)
Centers2
- These strategies might include increasing availability and accessibility of SARS-CoV-2 testing, contact tracing, isolation options, preventive care, disease management, and prevention guidance to facilities (e.g., clinics, community centers, and businesses) in areas with high levels of deprivation. (cdc.gov)
- Another problem with food addiction research is that it centers on responses - real or theoretical - to "hyperpalatable" foods high in sugar, fat and sometimes caffeine. (seattletimes.com)
Findings3
- These findings will pave the way for better food labelling and greater understanding of the factors that can lead to allergic reactions. (food.gov.uk)
- Findings from a study published in the journal Nature Communications found that losing sleep can make you more likely to crave junk food rather than healthy food. (goqii.com)
- The findings, from 30 adults with normal insulin sensitivity and normal weight and 24 adults with impaired insulin sensitivity and obesity, suggest that metabolic signals, particularly ones that promote energy restoration in a setting of energy deprivation caused by insulin or a glucagon-like peptide-1 (GLP-1) receptor agonist, "profoundly influence neuronal processing," said Tittgemeyer. (medscape.com)
Consumed meals1
- The study, published in the journal SLEEP, found that subjects who were sleep-deprived were more likely to consume junk foods offered to them, even when they had recently consumed meals that offered 90 percent of their necessary caloric intake. (glamour.com)
Stress1
- Headache may be triggered or worsen with certain types of foods, activities, medications, or stress. (americanheadachesociety.org)
Health7
- To better understand how area-level deprivation might reinforce ethnic, racial, and workplace-based COVID-19 inequities ( 3 ), the Utah Department of Health (UDOH) analyzed confirmed cases of infection with SARS-CoV-2 (the virus that causes COVID-19), COVID-19 hospitalizations, and SARS-CoV-2 testing rates in relation to deprivation as measured by Utah's Health Improvement Index (HII) ( 4 ). (cdc.gov)
- Local jurisdictions should use measures of deprivation and other social determinants of health to enhance transmission reduction strategies (e.g., increasing availability and accessibility of SARS-CoV-2 testing and distributing prevention guidance) to areas with greatest need. (cdc.gov)
- This study utilised an innovative application of spatial cluster analysis to examine the socio-spatial patterning of outlets selling potentially health-damaging goods/services, such as alcohol, fast food, tobacco and gambling, within Glasgow City, Scotland. (nih.gov)
- 95, Dutton), says it's time for black women to make the connection between soul food, weight and bad health. (nydailynews.com)
- While it's long been understood that mental health conditions like depression often trigger issues like insomnia or oversleeping , recent research suggests the relationship between sleep deprivation and depression is bidirectional. (verywellhealth.com)
- Today environmental justice addresses disparate social conditions holistically, working to bring justice for communities that experience food deserts, climate change, inaccessible transportation and health needs, economic deprivation, dilapidated housing, and other environmental hazards that directly impact human health and human life. (cdc.gov)
- It includes consideration of access to food, public health services and the ability to actively respond to risks 8 . (bvsalud.org)
Levels8
- It provides cut-off levels appropriate for the UK population which longer-term could help regulators and the food industry develop accurate evidence-based food labelling - keeping consumers safe and enabling greater variety of diet. (food.gov.uk)
- Sleep deprivation leads to increased blood levels of ghrelin, a hormone that increases hunger. (goqii.com)
- However, there was no correlation between individual ghrelin levels and food purchasing, suggesting that other mechanisms such as impulsive decision making may be more responsible for increased purchasing. (goqii.com)
- According to Expedia's 23rd annual Vacation Deprivation Report, global vacation deprivation levels are the highest they've been in 10 years. (ksdk.com)
- To figure out why sleep-deprived subjects were eating more, the authors also measured participants' blood levels of endocannabinoids-chemicals known to enhance the desire for food intake that are also found in the bloodstream after marijuana consumption. (glamour.com)
- Developmental changes in the responsiveness of hypothalamic ER alpha mRNA levels to food deprivation. (nel.edu)
- Iwasa T, Matsuzaki T, Kinouchi R, Gereltsetseg G, Murakami M, Kuwahara A, Yasui T, Irahara M. Developmental changes in the responsiveness of hypothalamic ER alpha mRNA levels to food deprivation. (nel.edu)
- epidemic towards decreased physical activity in 2013, 23.8% (95% uncertainty levels - because of the increasing- interval [UI], 22.9-24.7%) of boys Obesity is a result of a positive en- ly sedentary nature of recreational and 22.6% (95% UI, 21.7-23.6%) ergy balance (i.e. energy intake that activities, changing modes of trans- of girls were overweight or obese. (who.int)
Alcohol5
- Do 'environmental bads' such as alcohol, fast food, tobacco, and gambling outlets cluster and co-locate in more deprived areas in Glasgow City, Scotland? (nih.gov)
- Co-location of individual types of outlets (alcohol, fast food, tobacco and gambling) within similar geographical areas was also evident. (nih.gov)
- Food addiction is a hot topic, but the idea that we can become addicted to food in the same way we might become addicted to drugs or alcohol is also very controversial . (seattletimes.com)
- It was based on Yale University research suggesting that in people who report food addiction, eating addictive foods trigger brain responses that look very similar to responses to alcohol or hard drugs. (seattletimes.com)
- Food is far more complex than a single substance like cocaine or alcohol. (seattletimes.com)
Chronic2
- This seems like a good place to point out that human food addiction studies generally don't assess attitudes about "good" and "bad" foods, nor do they screen for history of chronic dieting or disordered eating . (seattletimes.com)
- Studies suggest that chronic sleep deprivation, or reduced sleep over time, may lead to depression due to changes in the brain's neurotransmitter serotonin. (verywellhealth.com)
Behavior2
- however, this increase did not correlate with food purchasing behavior. (goqii.com)
- DURHAM, NC and KING COUNTY, WA - An effort in King County, Washington, to add nutrition facts labeling to fast food menus had no effect on consumer behavior in its first year. (scienceblog.com)
Serotonin1
- Food relates directly to serotonin, a key hormone that - along with vitamin B6, B12 and folic acid - helps promote healthy sleep," says dietitian Kristin Kirkpatrick, RD. (clevelandclinic.org)
Diet4
- The key to working with foods that feel addicting, Evans said, is to begin to introduce them in your diet in a more regular way, with the goal of making all foods routine and predictable. (seattletimes.com)
- Second, it's the definition of a deprivation diet. (oprah.com)
- and 35.2% had food security/high diet quality. (cdc.gov)
- and food security/low diet quality with elevated A1c. (cdc.gov)
Malnutrition2
- With the analysis, it was possible to relate the prevalence of malnutrition with the processes of establishment of demand, taking into account that the privation of food may be paradoxically correlated to its refusal. (bvsalud.org)
- However, lack of adequate dietary intake of amino acids and proteins is a serious cause of malnutrition when food supplies are inadequate because of poverty, drought, floods, wars, and displacements of people as refugees. (cdc.gov)
Demonstrates1
- Interestingly enough, the food addiction research nicely demonstrates with rodents what I see in the clients I work with. (seattletimes.com)
Studies1
- Based on animal studies, can things like food deprivation and antidepressants also promote neurogenesis or growth? (time.com)
Problem2
- I'm so glad that this important research is being done to help address the issue of food labelling which is real day-to-day problem for me. (food.gov.uk)
- Multiple feeding teams have noted that among children with nonorganic failure to thrive, there is frequently a subtle organic problem such as dysphagia, gastroesophageal reflux , constipation, or food allergy/intolerance that has created pain and/or fear in this cohort. (medscape.com)
Energy2
Environmental1
- Social vulnerability is a multifaceted concept often defined as the entirety of the social deficits faced by patients, including social and environmental inequalities and deprivation, which affect their social cohesion and capacity to respond to situations of social risk 6 . (bvsalud.org)
Report1
- If you have any concerns or information relating to fraud or criminality in food supply chains, or you wish to whistleblow regarding a food business for which you work, contact Food Crime Confidential on 0207 276 8787 (9am to 4pm Monday-Friday) or report via our online service . (food.gov.uk)
Adequate3
- Conscript soldiers in Russia performing their first year of compulsory military service are routinely denied adequate food and access to medical care, in violation of their human rights. (hrw.org)
- Human Rights Watch documented cases of denial of adequate food and medical care to first-year conscripts from more than fifty military units throughout Russia. (hrw.org)
- In some cases we documented, the denial of adequate food and medical care had grave consequences. (hrw.org)
Exercise2
- FSA funded research has found that exercise and sleep deprivation can put people with a peanut allergy at greater risk of a reaction. (food.gov.uk)
- This is not an exercise in deprivation. (pressherald.com)
Study2
- Led by the allergy research team at Addenbrooke's, and funded by The Food Standards Agency ( FSA ), the TRACE study is hugely significant, as one in every 100 adults and one in every 50 children, have peanut allergies - the most common cause of fatal allergic reactions. (food.gov.uk)
- A new study published in the journal Food Product Design, by Author Colin Chapman, MSc, of Uppsala University says that people who were deprived of one night's sleep purchased more calories and grams of food in a mock supermarket the following day. (goqii.com)
High6
- 95% CI = 2.98-3.24) in very high-deprivation areas, compared with those in very low-deprivation areas. (cdc.gov)
- The men were instructed to purchase as much as they could out of a possible 40 items, including 20 high-caloric foods and 20 low-caloric foods. (goqii.com)
- The prices of the high-caloric foods were then varied to determine if total sleep deprivation affects the flexibility of food purchasing. (goqii.com)
- This change in brain activity is further associated with an increase in the desire for weight gain promoting high-calorie foods following sleep deprivation. (goqii.com)
- The truth is that the high-fat, super-rich foods African-Americans have been piling on their plates for decades are hurting black women in ways they never imagined. (nydailynews.com)
- It's meant to be a celebration of the abundance of the high-quality food we have in Maine in August. (pressherald.com)
Global1
- The most important of the beneficial effects are increasing global and regional food supplies and increased nutritional quality of available foods. (cdc.gov)
Economic1
- Coronavirus disease 2019 (COVID-19) has had a substantial impact on racial and ethnic minority populations and essential workers in the United States, but the role of geographic social and economic inequities (i.e., deprivation) in these disparities has not been examined ( 1 , 2 ). (cdc.gov)
Intake1
- This is rather consequential for understanding food-intake behaviors. (medscape.com)
Night2
- On the morning after one night of total sleep deprivation, as well as after one night of sleep, the researchers gave 14 normal-weight men a fixed budget (approximately $50). (goqii.com)
- On the other hand, acute sleep deprivation (such as one night without sleep) may help combat depression, though this is not without side effects and more research is needed before this can be considered a treatment option. (verywellhealth.com)
Higher3
- rates of hospitalization and testing were also higher in higher-deprivation areas. (cdc.gov)
- Researchers at Uppsala University investigated whether sleep deprivation may impair or alter an individual's food purchasing choices based on its established tendency to impair higher-level thinking and to increase hunger. (goqii.com)
- They hypothesised that sleep deprivation's impact on hunger and decision making would make for the 'perfect storm' with regard to shopping and food purchasing - leaving individuals hungrier and less capable of employing self-control and higher level decision making processes to avoid making impulsive, calorie-driven purchases. (goqii.com)
Stronger2
- But if you're sleep deprived, your hedonic drive for certain foods gets stronger, and your ability to resist them may be impaired. (glamour.com)
- When food is restricted, our brains are brilliant enough to create an even stronger reward when we finally do eat those forbidden foods. (seattletimes.com)
Life3
- That couple, a life-coaching duo named Akahi Ricardo and Camila Castillo, belong to a community of people who believe you don't need food to live, that surviving on non-food substances like sunlight, air, and "prana" allows people to live more evolved, healthy, spiritual lives. (gq.com)
- Going without water is something that most doctors consider dangerous, but for Breatharians, an "initiation" fast is essential to beginning a life where food is optional. (gq.com)
- Why give up a central part of human life, go against medical advice, when there are so many spiritual practices out there that don't require you to give up food? (gq.com)
Relationship1
- I don't mean to oversimplify this, as food and our relationship to it can become incredibly complex. (seattletimes.com)
Increase1
- In future, it could support precautionary allergen labelling so people will know exactly when a food poses a real risk to them which can increase the trust they have in their food. (food.gov.uk)
Meat1
- Might add a little meat to the bones, but soul food won't hurt a sistah. (nydailynews.com)
Time2
- I see this in my practice all the time and it's a completely normal response to deprivation," Evans said. (seattletimes.com)
- While it can be a challenging process, when people stop restricting and food loses that extra charge, the feelings of compulsion and loss of control tend to ease up over time," Evans said. (seattletimes.com)
Weight gain2
- They need to know that these foods not only cause serious weight gain, but that that weight can be linked to diabetes and hypertension and all the other diseases that tend to plague us. (nydailynews.com)
- Weight gain is not just about over-eating or the wrong food choices. (drhoffman.com)
Types of foods1
- Coincidentally - or not - these are the types of foods most likely to be labeled as "bad," and, let's face it, forbidden fruit tastes the sweetest. (seattletimes.com)
Organic2
- The Maine Organic Farmers and Gardeners Association is challenging anyone eating in Maine next month - residents, second-home owners, students and visitors alike - to take a pledge to consume as much local and organic food as they can. (pressherald.com)
- USDA Agricultural Census data released in May indicates it is getting easier to find local and organic food in Maine. (pressherald.com)
Calories1
- Eating 100 fewer calories a day?roughly three bites of a fast-food hamburger?could prevent the 1.8 to 2.0 pounds that the average person gains per year, according to new estimates by James Hill and colleagues. (scienceblog.com)
Certain foods1
- In other words, the more we label certain foods as "bad" and try to avoid them, the more attractive they become. (seattletimes.com)
Directly1
- The value of local food produced in Maine and sold directly to consumers here jumped from $25 million in 2012 to $38 million in 2017. (pressherald.com)
Modern1
- While our bodies are evolutionarily hard-wired to withstand periodic caloric deprivation, the ever-present cornucopia of modern food opportunities outstrips the output that our aging musculature can maintain. (drhoffman.com)
Real1
- You're starving yourself, and you'll gain the weight back when you start eating real food," Scritchfield says. (oprah.com)
Water2
Quality1
- The food conscripts do receive is often of poor quality, rotten, or bug-infested. (hrw.org)