Derivatives of acetic acid with one or more fluorines attached. They are almost odorless, difficult to detect chemically, and very stable. The acid itself, as well as the derivatives that are broken down in the body to the acid, are highly toxic substances, behaving as convulsant poisons with a delayed action. (From Miall's Dictionary of Chemistry, 5th ed)

Quantitative screening for benzodiazepines in blood by dual-column gas chromatography and comparison of the results with urine immunoassay. (1/150)

A dual-column retention index method is described for quantitative gas chromatographic (GC) screening of 26 benzodiazepine drugs and metabolites in the blood using DB-5 and DB-17 capillary columns and electron capture detection. The method involves a one-step, small-scale liquid-liquid extraction with ethyl acetate and derivatization with N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide with 1% tert-butyldimethylsilyl chloride. The results from the GC screening of 514 postmortem blood samples were compared to those obtained from urine immunoassay (Syva ETSplus with a 200-ng/mL cutoff). Both methods gave a negative result in 284 cases and a positive result in 149 cases. In 48 cases, urine was negative by immunoassay but blood was positive by GC. The opposite situation (blood negative, urine positive) was detected only in four cases. In 29 cases, an invalid result was obtained by urine by immunoassay: 26 blood samples of those cases were negative and three samples positive by GC. In postmortem forensic toxicology, the present GC method seems to be a good alternative to the common combination of urinary immunoassay followed by quantitative analysis of blood by chromatography.  (+info)

A high-performance liquid chromatographic method for the determination of monofluoroacetate. (2/150)

A simple isocratic high-performance liquid chromatographic (HPLC) method for the quantitative analysis of monofluoroacetic acid (MFA), the toxic substance of Dichapetalum cymosum, in plant material, rumen contents (gastric contents), and liver samples is described. A suitable HPLC column that gives optimum sensitivity, accuracy, precision, and separation of MFA is identified. A C-610 organic acid analysis column at ambient temperature with 0.02M H3PO4 as an eluent and ultraviolet detection at 210 nm is utilized to quantitate MFA. Using this method, the average percentage recovery in plant material, bovine liver, and rumen samples is 94.8%, and a detection limit of 12 microg/L is achievable.  (+info)

In vivo transposon mutagenesis of the methanogenic archaeon Methanosarcina acetivorans C2A using a modified version of the insect mariner-family transposable element Himar1. (3/150)

We present here a method for in vivo transposon mutagenesis of a methanogenic archaeon, Methanosarcina acetivorans C2A, which because of its independence from host-specific factors may have broad application among many microorganisms. Because there are no known Methanosarcina transposons we modified the mariner transposable element Himar1, originally found in the insect Hematobia irritans, to allow its use in this organism. This element was chosen because, like other mariner elements, its transposition is independent of host factors, requiring only its cognate transposase. Modified mini-Himar1 elements were constructed that carry selectable markers that are functional in Methanosarcina species and that express the Himar1 transposase from known Methanosarcina promoters. These mini-mariner elements transpose at high frequency in M. acetivorans to random sites in the genome. The presence of an Escherichia coli selectable marker and plasmid origin of replication within the mini-mariner elements allows facile cloning of these transposon insertions to identify the mutated gene. In preliminary experiments, we have isolated numerous mini-mariner-induced M. acetivorans mutants, including ones with insertions that confer resistance to toxic analogs and in genes that encode proteins involved in heat shock, nitrogen fixation, and cell-wall structures.  (+info)

Urinary metabolites of halothane in man. (4/150)

The urinary metabolites of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane) were investigated in five individuals given trace doses (25 muCi), and in three individuals given large doses (1 mCi) of radioactively labeled 14C-halothane. The latter were donor subjects for heart transplant operations. Separation of the nonvolatile urinary metabolites of halothane was accomplished by chemical extraction, electrophoresis, ion-exchange and high-pressure liquid chromatography, and gas chromatography. Identification of the individual metabolites was by nuclear magnetic resonance and mass spectrometry. Three major metabolites were identified: trifluoroacetic acid, N-trifluoroacetyl-2-aminoethanol, and N-acetyl-S-(2-bromo-2-chloro-1,1-difluoroethyl)-L-cysteine. Smaller unidentified radioactive peaks were also found. The presence of both ethanolamide and cysteine conjugates of halothane is of concern. These urinary products imply the presence of reactive intermediates. The conjugation of such intermediates to proteins and phospholipids may give rise to the high-molecular-weight covalently bound metabolites demonstrated to be present in the liver following halothane anesthesia. Elucidation of the structures of the urinary metabolites provides information important to an understanding of halothane metabolism and its potential hepatotoxicity.  (+info)

Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya. (5/150)

Streptomyces cattleya is unusual in that it produces fluoroacetate and 4-fluorothreonine as secondary metabolites. We now report the isolation of an NAD(+)-dependent fluoroacetaldehyde dehydrogenase from S. cattleya that mediates the oxidation of fluoroacetaldehyde to fluoroacetate. This is the first enzyme to be identified that is directly involved in fluorometabolite biosynthesis. Production of the enzyme begins in late exponential growth and continues into the stationary phase. Measurement of kinetic parameters shows that the enzyme has a high affinity for fluoroacetaldehyde and glycoaldehyde, but not acetaldehyde.  (+info)

Selectivity of protein oxidative damage during aging in Drosophila melanogaster. (6/150)

The purpose of the present study was to determine whether oxidation of various proteins during the aging process occurs selectively or randomly, and whether the same proteins are damaged in different species. Protein oxidative damage to the proteins, present in the matrix of mitochondria in the flight muscles of Drosophila melanogaster and manifested as carbonyl modifications, was detected immunochemically with anti-dinitrophenyl-group antibodies. Aconitase was found to be the only protein in the mitochondrial matrix that exhibited an age-associated increase in carbonylation. The accrual of oxidative damage was accompanied by an approx. 50% loss in aconitase activity. An increase in ambient temperature, which elevates the rate of metabolism and shortens the life span of flies, caused an elevation in the amount of aconitase carbonylation and an accelerated loss in its activity. Exposure to 100% ambient oxygen showed that aconitase was highly susceptible to undergo oxidative damage and loss of activity under oxidative stress. Administration of fluoroacetate, a competitive inhibitor of aconitase activity, resulted in a dose-dependent decrease in the life span of the flies. Results of the present study demonstrate that protein oxidative damage during aging is a selective phenomenon, and might constitute a mechanism by which oxidative stress causes age-associated losses in specific biochemical functions.  (+info)

Trifluoromethyl ketone-based inhibitors of apoptosis in cerebellar granule neurons. (7/150)

A variety of aromatic trifluoromethyl ketone derivatives has been studied as inhibitors of apoptosis in cerebellar granule neurons (CGNs). Among them, alpha-trifluoromethyl diketone (2) and benzyl trifluoromethyl ketone (11) were found to be apoptosis inhibitors which can prevent a neurodegenerative disease. Compounds 2 and 11 showed neuroprotection effect on low K+-induced apoptosis in CGNs. Furthermore, these compounds effectively suppressed DNA fragmentation accompanied with apoptosis. The neuroprotection mode of 2 and 11 was not related to inhibition of caspase-3.  (+info)

Catalysis-linked inactivation of fluoroacetate dehalogenase by ammonia: a novel approach to probe the active-site environment. (8/150)

Fluoroacetate dehalogenase from Moraxella sp. B (FAc-DEX) catalyzes the hydrolytic dehalogenation of fluoroacetate and other haloacetates. Asp(105) of the enzyme acts as a nucleophile to attack the alpha-carbon of haloacetate to form an ester intermediate, which is subsequently hydrolyzed by a water molecule activated by His(272) [Liu, J.Q., Kurihara, T., Ichiyama, S., Miyagi, M., Tsunasawa, S., Kawasaki, H., Soda, K., and Esaki, N. (1998) J. Biol. Chem. 273, 30897-30902]. In this study, we found that FAc-DEX is inactivated concomitantly with defluorination of fluoroacetate by incubation with ammonia. Mass spectrometric analyses revealed that the inactivation of FAc-DEX is caused by nucleophilic attack of ammonia on the ester intermediate to convert the catalytic residue, Asp(105), into an asparagine residue. The results indicate that ammonia reaches the active site of FAc-DEX without losing its nucleophilicity. Analysis of the three-dimensional structure of the enzyme by homology modeling showed that the active site of the enzyme is mainly composed of hydrophobic and basic residues, which are considered to be essential for an ammonia molecule to retain its nucleophilicity. In a normal enzyme reaction, the hydrophobic environment is supposed to prevent hydration of the highly electronegative fluorine atom of the substrate and contribute to fluorine recognition by the enzyme. Basic residues probably play a role in counterbalancing the electronegativity of the substrate. These results demonstrate that catalysis-linked inactivation is useful for characterizing the active-site environment as well as for identifying the catalytic residue.  (+info)

Fluoroacetates are organic compounds that contain a fluorine atom and an acetic acid group. The most well-known and notorious compound in this family is sodium fluoroacetate, also known as 1080 or compound 1080, which is a potent metabolic poison. It works by interfering with the citric acid cycle, a critical process that generates energy in cells. Specifically, fluoroacetates are converted into fluorocitrate, which inhibits an enzyme called aconitase, leading to disruption of cellular metabolism and ultimately cell death.

Fluoroacetates have been used as rodenticides and pesticides, but their use is highly regulated due to their high toxicity to non-target species, including humans. Exposure to fluoroacetates can cause a range of symptoms, including nausea, vomiting, seizures, and cardiac arrest, and can be fatal if not treated promptly.

... may refer to: Fluoroacetic acid Salts of fluoroacetic acid such as Sodium fluoroacetate Esters of fluoroacetic ... acid Fluoroethyl fluoroacetate Methyl fluoroacetate Fluoroaspirin 2-Ethylhexyl fluoroacetate This set index article lists ...
... is the fluoroacetate ester of 2-fluoroethanol. It is two times more toxic than methyl fluoroacetate. ... Methyl fluoroacetate Fluoroacetic acid Sodium fluoroacetate Fluoroacetamide 2-Fluoroethanol Kitano, Hisao; Fukui, Ken-ichi; ... a) 2-Fluoroethyl fluoroacetate and allied compounds. (b) 2 : 2′-Difluorodiethyl ethylene dithioglycol ether". J. Chem. Soc.: ... Fluoroacetates, Chemical weapons, Poisons, Fluoroethyl esters, All stub articles, Ester stubs). ...
The enzyme fluoroacetate dehalogenase has been discovered in a soil bacterium, which can detoxify fluoroacetate in the ... Fluoroacetamide Methyl fluoroacetate Fluoroethyl fluoroacetate Fluoroaspirin NIOSH Pocket Guide to Chemical Hazards. "#0564". ... Wikimedia Commons has media related to Sodium fluoroacetate. Sodium fluoroacetate, CDC - NIOSH Pocket Guide to Chemical Hazards ... Fluoroacetate occurs naturally in at least 40 plants in Australia, Brazil, and Africa. It is one of only five known organic ...
... presents a serious hazard as a food and water contaminant in the case that it is used as a poison against ... Methyl fluoroacetate is a methyl ester. The structure consists of a carboxylic acid as a functional group and a fluorine atom. ... Methyl fluoroacetate is produced and used as a chemical reagent and it can be released to the environment through several waste ... Methyl fluoroacetate (MFA) is an extremely toxic methyl ester of fluoroacetic acid. It is a colorless, odorless liquid at room ...
... is the fluoroacetate ester of 2-ethylhexanol. It can be produced by reaction of ethyl fluoroacetate ... 2-Ethylhexyl fluoroacetate is a liquid that is highly toxic by skin absorption. Methyl fluoroacetate Fluoroethyl fluoroacetate ... Horsfall, John L. (22 October 1946). "2-ethylhexyl fluoroacetate". v t e (Articles without InChI source, Articles without EBI ... Fluoroacetates, 2-Ethylhexyl esters, All stub articles, Ester stubs). ...
Saadi, Jakub; Wennemers, Helma (18 January 2016). "Enantioselective aldol reactions with masked fluoroacetates". Nature ... of fluorinated MAHTs and MTMs allowed for the stereoselective introduction of fluorine substituents in fluoroacetate aldol ...
New Zealand has used 1080 for pest control since the late 1950s; it imports sodium fluoroacetate in raw form from the United ... 1080, the brand name given to the synthetic form of sodium fluoroacetate, is used in New Zealand in efforts to control ... "1080 - Sodium fluoroacetate" (PDF). Department of Primary Industries & Fisheries, Queensland. Archived from the original (PDF) ... Fleury, Lauren M.; Scahill, Bryan G.; Taskova, Rilka (1 February 2016). "Determination of Sodium Fluoroacetate in Dairy Powders ...
Fluoroacetate is similar to acetate, which has a pivotal role in the Krebs cycle (a key part of cell metabolism). Fluoroacetate ... Sodium fluoroacetate has been used as an insecticide, but it is especially effective against mammalian pests. The name "1080" ... Insects fed 29-fluorostigmasterol use it to produce fluoroacetates. If a fluorine is transferred to a body cell, it blocks ... The most common example is fluoroacetate, with an active poison molecule identical to commercial "1080". It is used as a ...
The most common example is fluoroacetate, which occurs as a plant defence against herbivores in at least 40 plants in Australia ... The most common natural organofluorine species is fluoroacetate, a toxin found in a few species of plants. Others include ... Only a few organofluorine compounds are acutely bioactive and highly toxic, such as fluoroacetate and perfluoroisobutene.[ ... Proudfoot, Alex T; Bradberry, Sally M; Vale, J Allister (2006). "Sodium Fluoroacetate Poisoning". Toxicological Reviews. 25 (4 ...
The most common is fluoroacetate, which is used as a defense against herbivores by at least 40 plants in Africa, Australia and ... ISBN 978-0-226-68295-2. Proudfoot, A. T.; Bradberry, S. M.; Vale, J. A. (2006). "Sodium Fluoroacetate Poisoning". Toxicological ... Murphy, C. D.; Schaffrath, C.; O'Hagan, D. (2003). "Fluorinated Natural Products: The Biosynthesis of Fluoroacetate and 4- ... Beasley, Michael (August 2002). Guidelines for the safe use of sodium fluoroacetate (1080) (PDF). Wellington: Occupational ...
When inhaled by rats, 1,2-difluoroethane is converted to fluoroacetate using cytochrome P450 and then to fluorocitrate both ... "Toxnet Has Moved". KELLER, DOUGLAS A.; ROE, D. CHRISTOPHER; LIEDER, PAUL H. (1996). "Fluoroacetate-Mediated Toxicity of ...
Twigg; LE; Parker; RW (2010). "Is sodium fluoroacetate (1080) a humane poison? The influence of mode of action, physiological ...
... is the fluoroacetate ester of salicylic acid. It is the fluoroacetate analog of aspirin. Like other fluoroacetate ... Methyl fluoroacetate Fluoroethyl fluoroacetate Saunders, BC (1957). Some aspects of the chemistry and toxic action of organic ... Part I. Methyl Fluoroacetate and Related Compounds". J. Chem. Soc. 70: 1773-1779. doi:10.1039/JR9480001773. PMID 18106001. v t ... Fluoroacetates, Salicylic acids, Salicylyl esters, All stub articles, Organic compound stubs). ...
P. icterotis was used in a comparative study of tolerance in some Australian birds to sodium fluoroacetate, a highly toxic ... Twigg, L. E.; King, D. R. (1989). "Tolerance to Sodium Fluoroacetate in Some Australian Birds". Wildlife Research. 16 (1): 49- ...
Sodium fluoroacetate Trifluoroacetic acid Sodium acetate Chang, Ying; Cai, Chun (June 2005). "Trifluoromethylation of carbonyl ...
Fluorocitrate is formed in two steps from fluoroacetate. Fluoroacetate is first converted to fluoroacetyl-CoA by acetyl-CoA ...
... livestock are often killed by fluoroacetate poisoning. Fluoroacetate is lethal to sheep and cattle at doses of 0.25 to 0.5 mg/ ... A fluoroacetate dehalogenase gene from the soil bacterium Moraxella species strain B was transferred into the rumen bacterium ... For examples, in the case of fluoroacetate in will produce glycolate and fluoride. This enzyme belongs to the family of ... As fluoroacetate is poisonous and present in plants endemic to Australia, Africa, and Central America, ...
Fluoroacetic acid Methyl fluoroacetate Truce, William E. (August 1948). "The Preparation of Fluoroacetyl Chloride". Journal of ... he reacted sodium fluoroacetate with phosphorus pentachloride to obtain the desired compound. ...
This suggests that tammar wallabies originated in South Australia and developed a resistance to sodium fluoroacetate when they ... Pest control operators have used sodium fluoroacetate to control their populations, a practice which has been controversial ... Different tammar wallaby populations have varying levels of resistance to sodium fluoroacetate. Mainland Western Australian ... "Fluoroacetate Tolerance, a Genetic Marker in Some Australian Mammals". Australian Journal of Zoology. 27 (3): 363-72. doi: ...
... is inhibited by fluoroacetate, therefore fluoroacetate is poisonous. Fluoroacetate, in the citric acid cycle, can ...
Primarily the seed pods can be extremely poisonous, containing fluoroacetate. Sheep and cattle sometimes are poisoned after ...
Beasley, Michael (August 2002). "Guidelines for the safe use of sodium fluoroacetate (1080)" (PDF). New Zealand Occupational ... aerial treatment with sodium fluoroacetate, a biodegradable poison also known as 1080. From 1979 to 1984, possum control was ...
Beasley, Michael (August 2002). "Guidelines for the safe use of sodium fluoroacetate (1080)" (PDF). New Zealand Occupational ... a pesticide using sodium fluoroacetate, was "effective and safe". The government and Federated Farmers maintain it is an ...
... ultimately leading to the formation of fluoroacetaldehyde and then fluoroacetate. Fluoroacetate is a precursor to fluorocitrate ... In rats, it was found that fluoroethanol induced a similar toxicity as that of fluoroacetate, known to metabolize to ... https://doi.org/10.1042/bj0820129 Goncharov, N. V., Jenkins, R. O., & Radilov, A. S. (2006). Toxicology of fluoroacetate: a ...
Huang, S; Ma, L; Tong, MH; Yu, Y; O'Hagan, D; Deng, H (21 July 2014). "Fluoroacetate biosynthesis from the marine-derived ...
The conjugate base, fluoroacetate occurs naturally in at least 40 plants in Australia, Brazil, and Africa. It is one of only ... Fluoroacetic acid is used to manufacture pesticides especially rodenticides (see sodium fluoroacetate). The overall market is ...
Mead, R.J.; Oliver, A.J.; King, D.R.; Hubach, P.H. (March 1985). "The Co-Evolutionary Role of Fluoroacetate in Plant-Animal ...
More modern poisons for rabbit control are sodium fluoroacetate ("1080") and pindone. Another technique is hunting using ...
Donald A. Levin; King, Dennis R. (1991). "The Impact of Fluoroacetate-Bearing Vegetation on Native Australian Fauna: A Review ... The synthesis of fluoroacetate in several plants is an example of the use of small molecules to disrupt the metabolism of ...
Murphy CD, Schaffrath C, O'Hagan D (2003). "Fluorinated natural products: the biosynthesis of fluoroacetate and 4- ... fluoroacetate + NADH + 2 H+ The 3 substrates of this enzyme are fluoroacetaldehyde, NAD+, and H2O, whereas its 3 products are ... "Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces ... fluoroacetate, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or ...
Fluoroacetate may refer to: Fluoroacetic acid Salts of fluoroacetic acid such as Sodium fluoroacetate Esters of fluoroacetic ... acid Fluoroethyl fluoroacetate Methyl fluoroacetate Fluoroaspirin 2-Ethylhexyl fluoroacetate This set index article lists ...
Artikel ini berisi informasi lengkap Tentang Kelompok hacker Fluoroacetate "Membobol" Iphone X ... Kelompok hacker Fluoroacetate "Membobol" Iphone X di perlombaan peretasan Pwn2Own yang di adakan di tokyo, dengan memanfaatkan ...
Ethyl fluoroacetate poisoning can be fatal due to irreversible cellular dysfunction, especially in the CNS and circulatory ... Ethyl fluoroacetate poisoning can be fatal due to irreversible cellular dysfunction, especially in the CNS and circulatory ... A case of poisoning with ethyl fluoroacetate is presented in detail. Diagnostic problems and therapy which failed due to the ... An emphasis is on health hazards resulting from the exposure to fluoroacetate and necessity to observe strictly safety ...
Sodium fluoroacetate. 62-74-8. 1988. Sodium hydroxide. 1310-73-2. 1988. ...
Fluoroacetate *Hydrogen sulfide *Methanol *Phosphine Note: The actual clinical manifestations of an exposure to sodium azide ...
The use of sodium fluoroacetate as a rodenticide was greatly curtailed in the United States by 1990, because of its toxicity to ... Sodium fluoroacetate poisoning. Toxicol Rev. 2006. 25 (4):213-9. [QxMD MEDLINE Link]. ... Its toxicity stems from the similarity of fluoroacetate to acetate; the available evidence suggests that the fluoride component ...
Is sodium fluoroacetate (1080) a humane poison? The influence of mode of action, physiological effects, and target specificity ... 1080 (sodium fluoroacetate)-baiting programmes are an important and often the only option for reducing the impact of invasive ... Twigg, L.E. and Parker, R.W. (2010) Is sodium fluoroacetate (1080) a humane poison? The influence of mode of action, ... 1080 animal welfare ethical pest control fluoroacetate humaneness vertebrate pest virally-vectored immunocontraception ...
LR: 20131121; CI: Copyright (c) 2012; JID: 0370534; 0 (Acetamides); 0 (Acetonitriles); 0 (Fluoroacetates); 0 (Organosilicon ...
Fluoroacetate *Hydrogen sulfide *Methanol *Phosphine Note: The actual clinical manifestations of an exposure to sodium azide ...
Fluoroacetates*Squill and derivatives*Thallium*Warfarin*Zinc phosphide. E863.6. ICD9Data.com E863.8 ...
... control substance with some insecticidal properties and which is chemically and toxicologically identical to the fluoroacetate ...
1080 is the common name for a biodegradable poison called sodium fluoroacetate. Its made synthetically, but fluoroacetate is ...
Subforum: Fluoroacetate Topics: 6 6 Topics. 6 Posts. Last post. USA: Cryolite - Notice of Rec… by admin View the latest post ...
Subforum: Fluoroacetate Topics: 6 6 Topics. 6 Posts. Last post. USA: Cryolite - Notice of Rec… by admin View the latest post ...
Tracking 1080 (sodium fluoroacetate) in surface and subsurface flows during a rainfall event: a hillslope-scale field study. M ... Do toxic baits containing sodium fluoroacetate (1080) affect fish and invertebrate communities when they fall into streams? ... Consumption of baits containing sodium fluoroacetate (1080) by the New Zealand freshwater crayfish (Paranephrops planifrons). ...
Decarboxylative Organocatalyzed Addition Reactions of Fluoroacetate Surrogates for the Synthesis of Fluorinated Oxindoles. ...
Sodium- fluoroacetate has been widely used as a mammalian pest control agent. Although these compounds have different modes of ... Based on the acute toxicity to rats, fluoroacetate was the most toxic. ... sodium-fluoroacetate (62748), iodoacetic-acid (64697), sodium- iodoacetate (305533), and bromoacetic-acid (79083). Topics ...
Sodium fluoroacetate (also known as Sodium monofluoroacetate or Compound 1080) - Insecticide, Rodenticide - CAS No. 62-74-8 ...
1080 (sodium fluoroacetate) occurs naturally in some plants as a defence. It is considered so nasty a poison against mammals ...
It has previously been demonstrated for three proteins: fluoroacetate dehalogenase, hen egg-white lysozyme and human ...
1080 (sodium fluoroacetate) is lethal to pets (including domestic dogs and cats) and working dogs. In the event of accidental ... 1080 (sodium fluoroacetate) is lethal to pets (including domestic dogs and cats) and working dogs. In the event of accidental ... A baiting program using ground baits containing 1080 (sodium fluoroacetate) poison for the control of wild dogs and foxes will ... A ground baiting program using 1080 (sodium fluoroacetate) poison to control wild dogs will be conducted between Tuesday the ...
Researchers Amat Cama and Richard Zhu of team Fluoroacetate discovered a "JIT bug in the renderer" that allowed them to exploit ...
Sodium fluoroacetate - popularly known as Compound 1080 - was identified as one of the reasons behind the growth in dingoes, a ...
The operation will use 1080 (sodium fluoroacetate) poison for the control of foxes.. The program will take place in:. *Beowa ... The operation will use 1080 (sodium fluoroacetate) poison for the control of foxes.. The program will take place in:. *Beowa ...
Mechanism of toxicity for fluoroacetate *incorporated into the krebs cycle as fluoroacetyl CoA which binds the enzyme aconitase ...
Female 341, found dead of sodium fluoroacetate (Compound 1080) poisoning near Meeker, Colorado in 2009, is one unfortunate ...
CAUTION: Potential symptoms of overexposure to sodium fluoroacetate are vomiting; apprehension, auditory halucinations; facial ...
Carrot bait containing Sodium Fluoroacetate (1080) will be applied by ground.. There will be a toxic application between 4th of ...
Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat. Piel, S., Janowska, J ...
It is poisonous to stock due to fluoroacetate (1080 poison) compounds in the seeds and seed pods. These negative qualities are ... It is poisonous to stock due to fluoroacetate (1080 poison) compounds in the seeds and seed pods. These negative qualities are ...
  • Fluoroacetate may refer to: Fluoroacetic acid Salts of fluoroacetic acid such as Sodium fluoroacetate Esters of fluoroacetic acid Fluoroethyl fluoroacetate Methyl fluoroacetate Fluoroaspirin 2-Ethylhexyl fluoroacetate This set index article lists chemical compounds articles associated with the same name. (wikipedia.org)
  • The use of sodium fluoroacetate as a rodenticide was greatly curtailed in the United States by 1990, because of its toxicity to other mammals, and it is currently licensed only for use against coyotes. (medscape.com)
  • Is sodium fluoroacetate (1080) a humane poison? (qld.gov.au)
  • 1080 (sodium fluoroacetate)-baiting programmes are an important and often the only option for reducing the impact of invasive vertebrate pests on biodiversity and agricultural production in Australia and New Zealand. (qld.gov.au)
  • 1080 is the common name for a biodegradable poison called sodium fluoroacetate. (doc.govt.nz)
  • A detailed review and analysis was conducted of the biological effects of chloroacetic-acid (79118), sodium-chloroacetate (3926623), fluoroacetic-acid (144490), sodium-fluoroacetate (62748), iodoacetic-acid (64697), sodium- iodoacetate (305533), and bromoacetic-acid (79083). (cdc.gov)
  • Sodium- fluoroacetate has been widely used as a mammalian pest control agent. (cdc.gov)
  • The operation will use 1080 (sodium fluoroacetate) poison for the control of foxes. (nsw.gov.au)
  • Carrot bait containing Sodium Fluoroacetate (1080) will be applied by ground. (orc.govt.nz)
  • This bill would ban two deadly poisons-sodium fluoroacetate, commonly known as Compound 1080, and sodium cyanide, commonly known as M-44 devices-which are used by the US Department of Agriculture's Wildlife Services program to kill thousands of coyotes and foxes perceived as threats to livestock each year. (awionline.org)
  • They may behave differently in response to baiting and there is evidence that susceptibility to the commonly-used poison sodium fluoroacetate is higher in possums of mainland origin. (edu.au)
  • The NSW National Parks and Wildlife Service (NPWS) will be conducting a baiting program using manufactured baits, fresh baits and Canid Pest Ejectors (CPE's/ejectors) containing 1080 poison (sodium fluoroacetate) for the control of foxes. (ymlp.com)
  • It is poisonous to stock due to fluoroacetate (1080 poison) compounds in the seeds and seed pods. (opbg.com.au)
  • Decarboxylative Organocatalyzed Addition Reactions of Fluoroacetate Surrogates for the Synthesis of Fluorinated Oxindoles. (nih.gov)
  • Based on the acute toxicity to rats, fluoroacetate was the most toxic. (cdc.gov)
  • It's made synthetically, but fluoroacetate is also produced naturally by some plants to deter browsing. (doc.govt.nz)
  • Is sodium fluoroacetate (1080) a humane poison? (qld.gov.au)
  • 1080 (sodium fluoroacetate)-baiting programmes are an important and often the only option for reducing the impact of invasive vertebrate pests on biodiversity and agricultural production in Australia and New Zealand. (qld.gov.au)
  • Molecular structure of highly toxic Sodium fluoroacetate (known as 1080). (fluoridealert.org)
  • The operation will use 1080 (sodium fluoroacetate) poison for the control of foxes. (nsw.gov.au)
  • See where pesticides including sodium fluoroacetate (1080) have been laid, or will be laid on public conservation land. (doc.govt.nz)
  • Carcasses and viscera of coyotes poisoned by Compound 1080 (sodium fluoroacetate) in single-dose tallow baits (SOBs) were fed to 3 coyotes, 3 domestic dogs, 4 striped skunks, and 15 black-billed magpies to determine if these species would be poisoned secondarily. (escholarship.org)
  • Synthetically produced fluoroacetate is the active ingredient in 1080 baits for the control of rabbits, foxes, wild dogs and others. (honkeynuts.com.au)
  • Team Fluoroacetate (Amat Cama and Richard Zhu) earned the bragging rights - along with the coveted 'Master of Pwn' title - after racking up a total of 45 points during the competition, making them the single most successful of the three groups who competed. (portswigger.net)
  • Amat Cama and Richard Zhu, a pair of security researchers who go by the name Team Fluoroacetate, found vulnerabilities across multiple devices including an Alexa-powered Amazon Echo and a Samsung Galaxy S10 smartphone. (acm.org)
  • Team Fluoroacetate compromised the devices at an international bug bounty event called Pwn2Own in Tokyo, hosted by Zero Day Initiative. (acm.org)
  • the brush-tailed possum (t. vulpecula) from western australia was found to be nearly 150 times more resistant to fluoroacetate intoxication in vivo than the same species from south australia. (liverpool.ac.uk)
  • Whereas many native animals have developed tolerance to fluoroacetate, introduced species are highly sensitive to poisoning. (honkeynuts.com.au)
  • Fluoroacetate, found in the leaves, flowers, seeds and wood, disrupts the energy producing tricarboxylic acid (TCA) cycle in the mitochondria of grazing animals. (honkeynuts.com.au)
  • Fluoroacetate is equivalent to access, which is a current war in the Krebs request( a pop-historian thetwo of page cause). (kroemmling.de)
  • acetone powder preparations from the liver of animals from both populations showed similar abilities to convert fluoroacetate into fluorocitrate. (liverpool.ac.uk)