Shigella flexneri: A bacterium which is one of the etiologic agents of bacillary dysentery (DYSENTERY, BACILLARY) and sometimes of infantile gastroenteritis.Shigella: A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that ferments sugar without gas production. Its organisms are intestinal pathogens of man and other primates and cause bacillary dysentery (DYSENTERY, BACILLARY).Shigella sonnei: A lactose-fermenting bacterium causing dysentery.Dysentery, Bacillary: DYSENTERY caused by gram-negative rod-shaped enteric bacteria (ENTEROBACTERIACEAE), most often by the genus SHIGELLA. Shigella dysentery, Shigellosis, is classified into subgroups according to syndrome severity and the infectious species. Group A: SHIGELLA DYSENTERIAE (severest); Group B: SHIGELLA FLEXNERI; Group C: SHIGELLA BOYDII; and Group D: SHIGELLA SONNEI (mildest).Shigella dysenteriae: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that is extremely pathogenic and causes severe dysentery. Infection with this organism often leads to ulceration of the intestinal epithelium.Shigella boydii: One of the SHIGELLA species that produces bacillary dysentery (DYSENTERY, BACILLARY).Shigella Vaccines: Vaccines or candidate vaccines used to prevent bacillary dysentery (DYSENTERY, BACILLARY) caused by species of SHIGELLA.Keratoconjunctivitis: Simultaneous inflammation of the cornea and conjunctiva.O Antigens: The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Bacterial Proteins: Proteins found in any species of bacterium.Virulence: The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.Congo Red: An acid dye used in testing for hydrochloric acid in gastric contents. It is also used histologically to test for AMYLOIDOSIS.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Antigens, Bacterial: Substances elaborated by bacteria that have antigenic activity.Serotyping: Process of determining and distinguishing species of bacteria or viruses based on antigens they share.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Genes, Bacterial: The functional hereditary units of BACTERIA.Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.Virulence Factors: Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)Salmonella: A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that utilizes citrate as a sole carbon source. It is pathogenic for humans, causing enteric fevers, gastroenteritis, and bacteremia. Food poisoning is the most common clinical manifestation. Organisms within this genus are separated on the basis of antigenic characteristics, sugar fermentation patterns, and bacteriophage susceptibility.Feces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.HeLa Cells: The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.Bacterial Vaccines: Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.Dysentery: Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Shiga Toxins: A class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS. They include SHIGA TOXIN which is produced by SHIGELLA DYSENTERIAE and a variety of shiga-like toxins that are produced by pathologic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157.Gene Expression Regulation, Bacterial: Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.Plesiomonas: A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in fish and other aquatic animals and in a variety of mammals, including man. Its organisms probably do not belong to the normal intestinal flora of man and can cause diarrhea.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Bacterial Outer Membrane Proteins: Proteins isolated from the outer membrane of Gram-negative bacteria.Lipopolysaccharides: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)Rhamnose: A methylpentose whose L- isomer is found naturally in many plant glycosides and some gram-negative bacterial lipopolysaccharides.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Enterobacteriaceae: A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.Disk Diffusion Antimicrobial Tests: A method where a culturing surface inoculated with microbe is exposed to small disks containing known amounts of a chemical agent resulting in a zone of inhibition (usually in millimeters) of growth of the microbe corresponding to the susceptibility of the strain to the agent.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Trimethoprim Resistance: Nonsusceptibility of bacteria to the action of TRIMETHOPRIM.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.BooksPublishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Acanthamoeba: A genus of free-living soil amoebae that produces no flagellate stage. Its organisms are pathogens for several infections in humans and have been found in the eye, bone, brain, and respiratory tract.Containment of Biohazards: Provision of physical and biological barriers to the dissemination of potentially hazardous biologically active agents (bacteria, viruses, recombinant DNA, etc.). Physical containment involves the use of special equipment, facilities, and procedures to prevent the escape of the agent. Biological containment includes use of immune personnel and the selection of agents and hosts that will minimize the risk should the agent escape the containment facility.Communicable DiseasesAcetylesterase: An enzyme that catalyzes the conversion of acetate esters and water to alcohols and acetate. EC 3.1.1.6.Triacetin: A triglyceride that is used as an antifungal agent.EsterasesTriolein: (Z)-9-Octadecenoic acid 1,2,3-propanetriyl ester.beta-Galactosidase: A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Shigella flexneri at Who Named It? Griffen Jr, WO. "Jacob: the other Flexner". Ann Surg. 239 (6): 808-17. doi:10.1097/01.sla. ... The bacteria species Shigella flexneri was named in recognition of Flexner. In addition, Flexner was the first to describe ...
Shigella flexneri use AI-2 to mediate virulence. The major virulence factor in Shigella is the plasmid vir B. The AI-2 ... 2016). Cell signaling Quorum sensing Day; Maurelli (2001). "Shigella flexneri LuxS Quorum-Sensing System Modulates virB ... It is likely the high concentrations of AI-2 produced by normal gut flora effect the production of AI-2 in Shigella and its ...
In 2001 images of NCs from Shigella flexneri were digitally analyzed and averaged to obtain a first semi-3D structure of the NC ... The helical structure of NCs from Shigella flexneri was resolved at a resolution of 16 Å using X-ray fiber diffraction in 2003 ... One of the most researched T3SS effector is IpaB from Shigella flexneri. It serves a double role, both as a translocator, ... and later the crystal structure of MixH from Shigella flexneri, which were both resolved in 2006. In 2012, a combination of ...
Jankowski W, Mankowski T, Chojnacki T (1974). "Formation of polyprenol monophosphate glucose in Shigella flexneri". Biochim. ...
Clark, C. S.; Maurelli, A. T. (2007). "Shigella flexneri Inhibits Staurosporine-Induced Apoptosis in Epithelial Cells". ... "The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes". The Journal of Cell Biology. ... "Calpain Activation by the Shigella flexneri Effector VirA Regulates Key Steps in the Formation and Life of the Bacterium's ... By contrast, internalized Shigella avoids the endolysosome system by rapidly lysing its vacuole through the action of the T3SS ...
Oglesby, A. G.; Murphy, E. R.; Iyer, V. R.; Payne, S. M. (2005). "Fur regulates acid resistance in Shigella flexneri via RyhB ... Murphy, E. R.; Payne, S. M. (2007). "RyhB, an Iron-Responsive Small RNA Molecule, Regulates Shigella dysenteriae Virulence". ...
"DNA supercoiling and environmental regulation of virulence gene expression in Shigella flexneri". Nature. 344 (6268): 789-792. ...
... and intercellular spreading of Shigella flexneri". J. Biol. Chem. 275 (37): 28893-901. doi:10.1074/jbc.M003882200. PMID ...
... and intercellular spreading of Shigella flexneri". The Journal of Biological Chemistry. 275 (37): 28893-901. doi:10.1074/jbc. ...
"Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and ... "Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri". The EMBO Journal. 17 ( ... and intercellular spreading of Shigella flexneri". The Journal of Biological Chemistry. 275 (37): 28893-901. doi:10.1074/jbc. ... and intercellular spreading of Shigella flexneri". The Journal of Biological Chemistry. 275 (37): 28893-901. doi:10.1074/jbc. ...
Shigella flexneri and Shigella dysenteriae. A study in China indicated that Shigella flexneri 2a was the most common serotype. ... The term is usually restricted to Shigella infections. Shigellosis is caused by one of several types of Shigella bacteria. ... There are several Shigella vaccine candidates in various stages of development that could reduce the incidence of dysentery in ... In addition, chronic arthritis secondary to S. flexneri infection, called reactive arthritis, may be caused by a bacterial ...
2003). "Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T". Infection and ... 2002). "Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia ... 2005). "Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery". Nucleic Acids Res. 33 ...
... is a small regulatory non-coding RNA encoded by the virulence plasmid of Shigella flexneri, a Gram-negative pathogenic ... Bernardini, M.L. (1989). "Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and ... Giangrossi, M. (2010). "A novel antisense RNA regulates at transcriptional level the virulence gene icsA of Shigella flexneri ... It is a first regulatory RNA characterised in S. flexneri. The RNA is 450 nucleotides long (which makes it one of the largest ...
Yao X, Wang HL, Shi ZX, Yan XY, Feng EL, Yang BL, Huang LY (2003). "Identification of RanBMP interacting with Shigella flexneri ...
Actoclampin motors also propel such intracellular pathogens as Listeria monocytogenes, Shigella flexneri, Vaccinia and ...
Homologous RNA genes have been found in other species such as Shigella flexneri and Salmonella species. The molecular function ...
Hemolysin E (HlyE) is a novel pore-forming toxin of Escherichia coli, Salmonella typhi, and Shigella flexneri. HlyE is ...
The IS128 RNA is a non-coding RNA found in bacteria such as Escherichia coli and Shigella flexneri. The RNA is 209 nucleotides ...
Schuch R, Maurelli AT (1999). "The Mxi-Spa Type III Secretory Pathway of Shigella flexneri Requires an Outer Membrane ...
The IS102 RNA is a non-coding RNA that is found in bacteria such as Shigella flexneri and Escherichia coli. The RNA is 208 ...
Found in the outer membrane of gram-negative enterobacteria such as Shigella flexneri, Yersinia pestis, Escherichia coli, and ...
Two basic forms are present in bacteria: Listeria monocytogenes, some species of Rickettsia, Shigella flexneri and other ... Shigella flexneri and Rickettsia conorii" (PDF). Journal of Cell Science. 112 (Pt 11): 1697-708. PMID 10318762. Lambrechts A, ... L. monocytogenes and S. flexneri both generate a tail in the form of a "comet tail" that gives them mobility. Each species ... with Listeria and Shigella found to be the fastest. Many experiments have demonstrated this mechanism in vitro. This indicates ...
Beloin, C.; Deighan, P.; Doyle, M.; Dorman, C. J. (2003-10-01). "Shigella flexneri 2a strain 2457T expresses three members of ...
The t44 gene is found between the map and rpsB genes in all species in the full alignment apart from Shigella flexneri. The ...
Additionally, Congo red is used for the diagnostics of the Shigella flexneri serotype 2a, where the dye binds the bacterium's ... Furthermore, Congo red may also be used to induce expression of the type III secretion system of Shigella flexneri, bringing ...
Kopā ar Shigella flexneri Shigella dyseneriae ir ļoti izplatītas jaunattīstības valstīs. Shigella dysenteriae spēj izraisīt ... Shigella dysenteriae Vikikrātuvē. Shigella dysenteriae ir gramnegatīvas nekustīgas nūjiņveidīgas baktērijas[1]. Ir bakteriālās ... Pirmā serotipa Shigella dysenteriae producē šigatoksīnu (ST), atšķiroties no citām Shigella pārstāvjiem, kuri producē ... Rezistence pret antibiotikām Shigella dysenteriae baktērijai parādās ātrāk nekā pārējiem Shigella pārstāvjiem. ...
Shigella flexneri. Shigella flexneri 1235-66. Shigella flexneri serotype X (strain 2002017). Shigella flexneri 4c. 319. ... Shigella flexneri. Shigella flexneri 1235-66. Shigella flexneri serotype X (strain 2002017). Shigella flexneri 4c. Escherichia ... Shigella flexneri. Shigella flexneri 1235-66. Shigella flexneri serotype X (strain 2002017). Shigella flexneri 4c. Escherichia ... Shigella flexneri. ,p>This subsection of the Names and taxonomy section shows the unique identifier assigned by the ,span ...
... in Shigella flexneri strains isolated from Chilean children with acute diarrhea. Material and methods: Thirty one Shigella ... FARFAN U, Mauricio et al. Molecular characterization of resistance mechanisms to chloramphenicol in Shigella flexneri strains ... Palabras clave : Chloramphenicol o-acetyl-transferase; Chloramphenicol resistance; Genes; cat; Shigella flexneri. ... Conclusions: Resistance to chloramphenicol in this group of Shigella flexneri strains was mediated by a chromosomally located ...
The purification of the Shigella flexneri virulence plasmid. The purification of the Shigella flexneri virulence plasmid. Save ... The identification of the stability genes encoded in the Shigella flexneri virulence plasmid would greatly increase our abi ... The intent of this research project was to purify the Shigella flexneri virulence plasmid without the use of ultra- ... The identification of the stability genes encoded in the Shigella flexneri virulence plasmid would greatly increase our ability ...
Biochemical Test of Shigella flexneri, Shigella, Shigella flexneri, Shigella flexneri Biochemical Test Leave a comment ... Biochemical Test of Shigella flexneri -Basic Characteristics Properties (Shigella flexneri) Catalase Positive (+ve) Citrate ... Shigella flexneri Biochemical Test of Bacteria. January 10, 2020. December 10, 2019. by Sagar Aryal ... Biochemical Test of Shigella flexneri. January 2, 2020. February 28, 2018. by Sagar Aryal ...
Shigella flexneri is a Gram-negative bacterium that is a significant cause of bacillary dysentery. Shigella uses its type III ... Analysis of the Tip Complex of the Type Iii Secretion Apparatus of Shigella Flexneri ... Post a Comment for Analysis of the Tip Complex of the Type Iii Secretion Apparatus of Shigella Flexneri ... Add tags for Analysis of the Tip Complex of the Type Iii Secretion Apparatus of Shigella Flexneri ...
... in Shigella surviving exposure to oxidative stress agents and during Shigella invasion and plaque formation in a human colon ... An S. flexneri strain containing a deletion mutation in the iscSUA genes (UR022) was created and an earlier constructed S. ... Our data suggest that while suf oes not hinder growth or invasiveness, iscSUA is critical for S. flexneri invasion and normal ... There are several aspects of Shigella pathogenesis that are not well understood, including a number of genetic and cellular ...
Genome sequence of Shigella flexneri strain SP1, a diarrheal isolate that encodes an extended-spectrum β-lactamase ESBL. . ... In China, the species most frequently responsible for shigellosis is Shigella flexneri. S. flexneri remains largely unexplored ... Genome sequence of Shigella flexneri strain SP1, a diarrheal isolate that encodes an extended-spectrum β-lactamase ESBL. ... Genome sequence of Shigella flexneri strain SP1, a diarrheal isolate that encodes an extended-spectrum β-lactamase ESBL - ...
Shigella flexneri and Shigella dysenteriae. A study in China indicated that Shigella flexneri 2a was the most common serotype. ... The term is usually restricted to Shigella infections. Shigellosis is caused by one of several types of Shigella bacteria. ... There are several Shigella vaccine candidates in various stages of development that could reduce the incidence of dysentery in ... In addition, chronic arthritis secondary to S. flexneri infection, called reactive arthritis, may be caused by a bacterial ...
The aim of current study was to describe fatal cases of shigellosis due to infection with Shigella sonnei and S. flexneri. ... Stool cultures yielded S. flexneri and S. sonnei for one and two cases, respectively. The isolates were resistant to ... flexneri as the cause of fatality among pediatric patients during the study. ... The aim of current study was to describe fatal cases of shigellosis due to infection with Shigella sonnei and S. flexneri. ...
Shigella flexneri and Shigella dysenteriae. One study in China indicated that Shigella flexneri 2a was the most common serotype ... The term is usually restricted to Shigella infections. Shigellosis is caused by one of several types of Shigella bacteria. ... an acute infection of the intestine by shigella bacteria; characterized by diarrhea and fever and abdominal pains ... Three species are associated with bacillary dysentery : Shigella sonnei, ...
Species-wide whole genome sequencing reveals historical global spread and recent local persistence in Shigella flexneri. ... Multidrug-resistant Shigella dysenteriae type 1 in south Asia. * Authors: Bhattacharya SK, Sarkar K, Balakrish Nair G, Faruque ... Genetic relatedness of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated in south Asia. ... A previous genomic study concluded that Shigella dysenteriae type 1 (Sd1), the epidemic dysentery bacillus, emerged and spread ...
Shigellaflexneri (group B), Shigella boydii (group C), and Shigella sonnei (group D) (4-6). Shigella cells include a virulent ... Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a. BMC Genomics. 2006; 7: 173[DOI][ ... Shigella flexneri 2a str. 2457T. NC_004741. 0.002698727. 35. E. coli PMV-1. NC_022370. 0.005606612. 62. E. coli O103:H2 str. ... Shigella flexneri 2a str 301. NC_004337. 0.002692293. 34. E. coli str. K-12 substr. W3110. NC_007779. 0.00558117. 61. E. coli ...
88Antibiogram Pattern of Shigella flexneri: Effect of BioField Treatment. *85Bio-field Treatment: A Potential Strategy for ... Keywords : shigella boydii,shigella boydii characteristics,antibiogram of shigella boydii,shigella boydii biochemical tests, ... 2Antibiogram Pattern of Shigella flexneri: Effect of BioField Treatment. *2Bio-field Treatment: A Potential Strategy for ... Antibiogram of Biofield-Treated Shigella boydii: Global Burden of Infections. Bacillary dysentery and acute gastroenteritis ...
"Shigella flexneri". NCBI Taxonomy Browser. 623. Type strain of Shigella flexneri at BacDive - the Bacterial Diversity ... Shigella flexneri is a species of Gram-negative bacteria in the genus Shigella that can cause diarrhea in humans. Several ... different serogroups of Shigella are described; S. flexneri belongs to group B. S. flexneri infections can usually be treated ... "The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response". Nature. 483 (7391): 623-6. doi: ...
Your basket is currently empty. i ,p>When browsing through different UniProt proteins, you can use the basket to save them, so that you can back to find or analyse them later.,p>,a href=/help/basket target=_top>More...,/a>,/p> ...
... During August 29-September 1, 1994, an outbreak of ... Shigella flexneri 2a has been isolated from fecal specimens from at least 12 ill passengers. Antimicrobial susceptibility ...
Shigella flexneri is a gram-negative bacterium which causes the most communicable of bacterial dysenteries, shigellosis. ... Shigella flexneri infection: pathogenesis and vaccine development.. Jennison AV1, Verma NK. ... The hosts humoral response to S. flexneri also appears to be important in protecting the host, whilst the role of the cellular ... The pathogenesis of S. flexneri is based on the bacterias ability to invade and replicate within the colonic epithelium, which ...
Shigella flexneri ATCC ® 700930™ Designation: 2457T TypeStrain=False Application: Emerging infectious disease and enteric ... Shigella flexneri Castellani and Chalmers (ATCC® 700930™) Strain Designations: 2457T / Type Strain: no / Biosafety Level: 2 ... of an IS1-like element into the virF gene is responsible for avirulence in opaque colonial variants of Shigella flexneri 2a.. ...
Shigella flexneri ATCC ® 12022™ Designation: CDC 3591-52 TypeStrain=False Application: Media testing Enteric Research Emerging ... Shigella flexneri Castellani and Chalmers (ATCC® 12022™) Strain Designations: CDC 3591-52 [CIP 104222] / Type Strain: no / ... Nucleotide (GenBank) : M13772 Shigella flexneri 2B crp gene encoding catabolite gene activator protein, complete cds. ...
1983) Characterization of virulence plasmids and plasmid-associated outer membrane proteins in Shigella flexneri, Shigella ... Shigella Minicells as a Model System for Elucidating T3SS Structure.. S. flexneri is an important diarrheal pathogen that uses ... 1999) The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes. J Cell Biol 147(3):683- ... Visualization of the type III secretion sorting platform of Shigella flexneri. Bo Hu, Dustin R. Morado, William Margolin, John ...
The S. flexneri cytotoxic genes have been localized to the ipa operon of shigellas virulence plasmid. ipaB, C and D deletion ... IpaB mediates macrophage apoptosis induced by Shigella flexneri.. Zychlinsky A1, Kenny B, Ménard R, Prévost MC, Holland IB, ... Shigella flexneri kills macrophages through apoptosis, involving the induction of host cell DNA fragmentation and ... Shigella can only cause damage if it escapes from the phagolysosome into the cytoplasm. ...
The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells. R Ménard, M C Prévost, P Gounon, P ... The bacterial pathogen Shigella flexneri causes bacillary dysentery in humans by invading coloncytes. Upon contact with ... The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells ... The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells ...
Shigella flexneri 2a. Shigella species are commonly pathogenic to humans, causing severe gastroenteritis (bacillary dysentery ... Shigella flexneri strain 2457T has been deposited with the American Type Culture Collection (ATCC) and is available as ATCC ... We have completed the genome sequence of Shigella flexneri serotype 2a strain 2457T, which has been the subject of extensive ... We have sequenced the large virulence plasmid pWR501 from Shigella flexneri serotype 5a, and it is available from Genbank with ...
Outbreak of Shigella flexneri and Shigella sonnei enterocolitis in men who have sex with men, Quebec, 1999 to 2001. Can Commun ... S. flexneri causes approximately 18% of U.S. Shigella infections (1). The national incidence of S. flexneri infections ... The persistence of Shigella flexneri in the United States: increasing role of adult males. Am J Public Health 1988;78:1432--5. ... Shigella flexneri Serotype 3 Infections Among Men Who Have Sex with Men --- Chicago, Illinois, 2003--2004. ...
Characterization of the rfc region of Shigella flexneri.. R Morona, M Mavris, A Fallarino, P A Manning ... Characterization of the rfc region of Shigella flexneri. Message Subject (Your Name) has forwarded a page to you from Journal ... The O antigen of the Shigella flexneri lipopolysaccharide (LPS) is an important virulence determinant and immunogen. We have ... A comparison of the S. flexneri rfc gene and protein product with other rfc and rfc-like proteins revealed that they have a ...
  • An S. flexneri strain containing a deletion mutation in the iscSUA genes (UR022) was created and an earlier constructed S. flexneri strain containing a deletion mutation in the entire suf operon (UR011) was verified. (richmond.edu)
  • It was the goal of this research to examine the roles of iscSUA and suf , gene systems predicted to encode for iron-sulfur cluster biosynthesis proteins, in Shigella surviving exposure to oxidative stress agents and during Shigella invasion and plaque formation in a human colon cell line. (richmond.edu)
  • Our data suggest that while suf oes not hinder growth or invasiveness, iscSUA is critical for S. flexneri invasion and normal growth. (richmond.edu)
  • There are several aspects of Shigella pathogenesis that are not well understood, including a number of genetic and cellular changes that allow Shigella to adapt to stresses encountered while invading and replicating within the eukaryotic cytosol. (richmond.edu)
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