Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
A plastic substance deposited by insects or obtained from plants. Waxes are esters of various fatty acids with higher, usually monohydric alcohols. The wax of pharmacy is principally yellow wax (beeswax), the material of which honeycomb is made. It consists chiefly of cerotic acid and myricin and is used in making ointments, cerates, etc. (Dorland, 27th ed)
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
An autosomal recessive neurocutaneous disorder characterized by severe ichthyosis MENTAL RETARDATION; SPASTIC PARAPLEGIA; and congenital ICHTHYOSIS. It is caused by mutation of gene encoding microsomal fatty ALDEHYDE DEHYDROGENASE leading to defect in fatty alcohol metabolism.
Oxidoreductases that are specific for ALDEHYDES.
A genus of gram-negative, rod-shaped bacteria in the family ALTEROMONADACEAE. The inability to utilize carbohydrates is a distinguishing feature from other genera in the family.
Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Compounds in which one or more of the three hydroxyl groups of glycerol are in ethereal linkage with a saturated or unsaturated aliphatic alcohol; one or two of the hydroxyl groups of glycerol may be esterified. These compounds have been found in various animal tissue.
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
GLYCEROPHOSPHOLIPIDS in which one of the two acyl chains is attached to glycerol with an ether alkenyl linkage instead of an ester as with the other glycerophospholipids.
A subclass of enzymes which includes all dehydrogenases acting on primary and secondary alcohols as well as hemiacetals. They are further classified according to the acceptor which can be NAD+ or NADP+ (subclass 1.1.1), cytochrome (1.1.2), oxygen (1.1.3), quinone (1.1.5), or another acceptor (1.1.99).
The sebaceous glands situated on the inner surface of the eyelids between the tarsal plates and CONJUNCTIVA.
Organic compounds containing a carbonyl group in the form -CHO.
A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.
A zinc-containing enzyme which oxidizes primary and secondary alcohols or hemiacetals in the presence of NAD. In alcoholic fermentation, it catalyzes the final step of reducing an aldehyde to an alcohol in the presence of NADH and hydrogen.
The study, utilization, and manipulation of those microorganisms capable of economically producing desirable substances or changes in substances, and the control of undesirable microorganisms.
A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
The generic name for the group of aliphatic hydrocarbons Cn-H2n+2. They are denoted by the suffix -ane. (Grant & Hackh's Chemical Dictionary, 5th ed)
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
S-Acyl coenzyme A. Fatty acid coenzyme A derivatives that are involved in the biosynthesis and oxidation of fatty acids as well as in ceramide formation.
Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (From Enzyme Nomenclature 1992) EC 2.3.
Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.
A group of 16-carbon fatty acids that contain no double bonds.
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
Sets of enzymatic reactions occurring in organisms and that form biochemicals by making new covalent bonds.
FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
Enzymes that catalyze the formation of acyl-CoA derivatives. EC 6.2.1.
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives.
Electron-dense cytoplasmic particles bounded by a single membrane, such as PEROXISOMES; GLYOXYSOMES; and glycosomes.
An umbrella term used to describe a pattern of disabilities and abnormalities that result from fetal exposure to ETHANOL during pregnancy. It encompasses a phenotypic range that can vary greatly between individuals, but reliably includes one or more of the following: characteristic facial dysmorphism, FETAL GROWTH RETARDATION, central nervous system abnormalities, cognitive and/or behavioral dysfunction, BIRTH DEFECTS. The level of maternal alcohol consumption does not necessarily correlate directly with disease severity.
Drinkable liquids containing ETHANOL.
An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES.
Alcohols derived from the aryl radical (C6H5CH2-) and defined by C6H5CHOH. The concept includes derivatives with any substituents on the benzene ring.
The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.
Intracellular proteins that reversibly bind hydrophobic ligands including: saturated and unsaturated FATTY ACIDS; EICOSANOIDS; and RETINOIDS. They are considered a highly conserved and ubiquitously expressed family of proteins that may play a role in the metabolism of LIPIDS.
Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.
A family of enzymes that catalyze the stereoselective, regioselective, or chemoselective syn-dehydrogenation reactions. They function by a mechanism that is linked directly to reduction of molecular OXYGEN.

Effective method for activity assay of lipase from Chromobacterium viscosum. (1/502)

A method was devised for activity assay of the lipase [triacylglycerol acyl-hydrolase, EC] excreted from Chromobacterium viscosum into the culture medium; olive oil emulsified with the aid of Adekatol 45-S-8 (a non-ionic detergent, the ethoxylate of linear sec-alcohols having chain lengths of 10--16 carbon atoms) was used as the substrate. This method was specifically effective for Chromobacterium lipase acitvity assay, and was approximately twice as sensitive as the conventional method, in which polyvinyl alcohol is used for the emulsification of the substrate.  (+info)

Effects of short chain alkanols on the inducible nitric oxide synthase in a glial cell line. (2/502)

1. Ethanol inhibits inducible nitric oxide synthase (iNOS) expression in C6 glioma cells by an unknown mechanism. Because relatively high concentrations are needed for inhibition in drug-naive cells (IC50 approximately = to 150 mM), suppression due to cytotoxicity is one possible mechanism that has not been ruled out. Therefore, the present study examined the effects of ethanol and other alkanols on C6 glioma cell viability and iNOS activity to better understand the mechanism for inhibition. 2. iNOS expression was induced in cell culture with lipopolysaccharide and phorbol ester treatment. Nitrite accumulation in culture medium, the in vitro conversion of [3H]-L-arginine to [3H]-L-citrulline, and immunoblotting were used to quantify iNOS induction and activity. Trypan blue exclusion, extracellular release of lactate dehydrogenase, and quantity of total cell protein were used as measures of viability. 3. Short chain alkanols, methanol through 1-heptanol, concentration-dependently inhibited nitrite accumulation. Longer chain alkanols, 1-octanol and 1-decanol, did not except at cytotoxic concentrations. Experiments indicated short chain alkanol inhibition was not due to direct actions on iNOS catalytic activity, but that it transpires during iNOS induction. Immunoblots showed reduced iNOS protein levels. 4. Correlation analysis ruled out iNOS inhibition as being due to decreased cell number, total cell protein, or cell viability. In contrast, there was significant correlation with physical measures of lipophilicity. 5. In conclusion, inhibition of iNOS expression by ethanol and other short chain alkanols is not due to cytotoxicity. Instead, the strong correlation with lipophilicity suggests the inhibition derives from an interaction with unknown hydrophobic cellular sites.  (+info)

Plaunotol prevents indomethacin-induced gastric mucosal injury in rats by inhibiting neutrophil activation. (3/502)

BACKGROUND: Activated neutrophils play a critical role in indomethacin-induced gastric mucosal injury. AIM: To investigate the effect of plaunotol, an anti-ulcer agent, on neutrophil activation in vitro and its effect on gastric mucosal injury and gastric accumulation of neutrophils in rats given indomethacin. METHODS: Human monocytes and neutrophils were isolated from the peripheral blood of healthy volunteers. We examined the effect of plaunotol on neutrophil elastase release, production of O2-, intracellular calcium concentration and expression of adhesion molecules CD11b and CD18 in activated neutrophils in vitro. The effect of plaunotol on TNF-alpha production by monocytes stimulated with endotoxin also was investigated in vitro. The effect of plaunotol (100 mg/kg, p.o.) on gastric mucosal injury and neutrophil accumulation was investigated in male Wistar rats given indomethacin (30 mg/kg, p.o.). RESULTS: Plaunotol inhibited the fMLP-induced release of neutrophil elastase from activated neutrophils, as well as the opsonized zymosan-induced production of O2- by neutrophils. Plaunotol significantly inhibited increased levels of intracellular calcium, a second messenger of neutrophil activation, in vitro. The fMLP-induced increases in CD11b and CD18 expression were also inhibited by plaunotol in vitro. Plaunotol inhibited monocytic production of TNF-alpha, a potent activator of neutrophils. Both gastric mucosal injury and gastric neutrophil infiltration in rats given indomethacin were significantly inhibited by the oral administration of plaunotol. CONCLUSIONS: Plaunotol inhibits indomethacin-induced gastric mucosal injury, at least in part by inhibiting neutrophil activation.  (+info)

Interactions of 6-gingerol and ellagic acid with the cardiac sarcoplasmic reticulum Ca2+-ATPase. (4/502)

The inotropic/lusitropic effects of beta-adrenergic agonists on the heart are mediated largely by protein kinase A (PKA)-catalyzed phosphorylation of phospholamban, the natural protein regulator of the Ca2+ pump present in sarcoplasmic reticulum (SR) membranes. Gingerol, a plant derivative, is known to produce similar effects when tested in isolated cardiac muscle. The purpose of the present study was to compare the effects of gingerol and another plant derivative, ellagic acid, on the kinetics of the SR Ca2+ pump with those of PKA-catalyzed phospholamban phosphorylation to elucidate their mechanisms of Ca2+ pump regulation. As previously demonstrated for PKA, 50 microM gingerol or ellagic acid increased Vmax(Ca) of Ca2+ uptake and Ca2+-ATPase activity assayed at millimolar ATP concentrations in light cardiac SR vesicles. Unlike PKA, which decreases Km(Ca), neither compound had a significant effect on Km(Ca) in unphosphorylated vesicles. However, gingerol increased Km(Ca) in phosphorylated vesicles, in which Ca2+ uptake was significantly increased further at saturating Ca2+ and remained unchanged at subsaturating Ca2+. An inhibition of Ca2+ uptake by gingerol at micromolar MgATP concentrations was overcome with increasing MgATP concentrations. The stimulation of Ca2+ uptake attributable to gingerol in unphosphorylated microsomes at saturating Ca2+ was 30% to 40% when assayed at 0.05 to 2 mM MgATP and only about 12% in phosphorylated microsomes as well as in rabbit fast skeletal muscle light SR. The present results support the view that an ATP-dependent increase in Vmax(Ca) of the SR Ca2+ pump plays an important role in mediating cardiac contractile responses to gingerol and phospholamban-dependent beta-adrenergic stimulation.  (+info)

Steric hindrance is not required for n-alkanol cutoff in soluble proteins. (5/502)

A loss of potency as one ascends a homologous series of compounds (cutoff effect) is often used to map the dimensions of binding sites on a protein target. The implicit assumption of steric hindrance is rarely confirmed with direct binding measurements, yet other mechanisms for cutoff exist. We studied the binding and effect of a series of n-alkanols up to hexadecanol (C16) on two model proteins, BSA and myoglobin (MGB), using hydrogen-tritium exchange and light scattering. BSA binds the n-alkanols specifically and, at 1 mM total concentration, is stabilized with increasing potency up to decanol (C10), where a loss in stabilizing potency occurs. Cutoff in stabilizing potency is concentration-dependent and occurs at progressively longer n-alkanols at progressively lower total n-alkanol concentrations. Light scattering measurements of n-alkanol/BSA solutions show a smooth decline in binding stoichiometry with increasing chain length until C14-16, where it levels off at approximately 2:1 (alkanol:BSA). MGB does not bind the n-alkanols specifically and is destabilized by them with increasing potency until C10, where a loss in destabilizing potency occurs. Like BSA, MGB demonstrates a concentration-dependent cutoff point for the n-alkanols. Derivation of the number of methylenes bound at K(D) and the free energy contribution per bound methylene showed that no discontinuity existed to explain cutoff, rendering steric hindrance unlikely. The data also allow an energetic explanation for the variance of the cutoff point in various reductionist systems. Finally, these results render cutoff an untenable approach for mapping binding site sterics in the absence of complementary binding measurements, and a poor discriminator of target relevance to general anesthesia.  (+info)

Ruptured abdominal aortic aneurysm, a "two-hit" ischemia/reperfusion injury: evidence from an analysis of oxidative products. (6/502)

PURPOSE: Ruptured abdominal aortic aneurysm (RAAA) remains a lethal condition despite improvements in perioperative care. The consequences of RAAA are hypothesized to result from a combination of two ischemia/reperfusion events: hemorrhagic shock and lower torso ischemia. Ischemia/reperfusion results in tissue injury by diverse mechanisms, which include oxygen free radical-mediated injury produced from activated neutrophils, xanthine oxidase, and mitochondria. Oxygen-free radicals attack membrane lipids, resulting in membrane and subsequently cellular dysfunction that contributes to postoperative organ injury/failure. The purpose of this investigation was to quantify the oxidative injury that occurs as a result of the ischemia/reperfusion events in RAAAs and elective AAAs. METHODS: Blood samples were taken from 22 patients for elective AAA repair and from 14 patients for RAAA repair during the perioperative period. Plasma F(2)-isoprostanes were extracted, purified, and measured with an enzyme immunoassay. Aldehydes and acyloins were purified and quantified. Neutrophil oxidative burst was measured in response to a receptor independent stimulus (phorbol 12-myristate 13-acetate) with luminol-based chemiluminescence. RESULTS: Plasma from patients with RAAAs showed significantly elevated F(2)-isoprostane levels on arrival at hospital and were significantly elevated as compared with the levels of patients for elective repair throughout the perioperative period (two-way analysis of variance, P <.0001). Multiple regression showed a significant relationship between the phagocyte oxidative activity and F(2)-isoprostane levels (P <.013). Total acyloin levels were significantly higher in patients with RAAAs as compared with the levels in elective cases. CONCLUSION: The F(2)-isoprostane levels, specific markers of lipid peroxidation, showed that patients with RAAAs had two phases of oxidative injury: before arrival at hospital and after surgery. The significant relationship between the postoperative increases in F(2)-isoprostane levels and the neutrophil oxidant production implicates neutrophils in the oxidative injury that occurs after RAAA. New therapeutic interventions that attenuate neutrophil-mediated oxidant injury during reperfusion may decrease organ failure and ultimately mortality in patients with RAAAs.  (+info)

Effects of a lipoxygenase inhibitor, panaxynol, on vascular contraction induced by angiotensin II. (7/502)

We investigated whether a lipoxygenase inhibitor, panaxynol, affected the vascular contraction induced by angiotensin (Ang) II and the mean arterial pressure in spontaneously hypertensive rats (SHR). Panaxynol suppressed dose-dependently the contractile responses induced by 30 nM Ang II in isolated intact and endothelial cell-denuded aorta in the hamster. IC50 values in the intact and endothelial cell-denuded aorta were 23 and 20 microM, respectively. In SHR, the mean arterial pressure after injection of 30 and 60 mg/kg panaxynol was reduced, and the maximum hypotensive values were 23 and 48 mmHg, respectively. Thus, lipoxygenase products may affect the renin-angiotensin system.  (+info)

Effect of policosanol on cerebral ischemia in Mongolian gerbils. (8/502)

Policosanol is a mixture of higher aliphatic primary alcohols isolated from sugar cane wax, whose main component is octacosanol. An inhibitory effect of policosanol on platelet aggregation and cerebral ischemia in animal models has been reported. Thus, the objective of the present study was to evaluate the effect of policosanol on cerebral ischemia induced by unilateral carotid ligation and bilateral clamping and recirculation in Mongolian gerbils. Policosanol (200 mg/kg) administered immediately after unilateral carotid ligation and at 12- or 24-h intervals for 48 h significantly inhibited mortality and clinical symptoms when compared with controls, whereas lower doses (100 mg/kg) were not effective. Control animals showed swelling (tissue vacuolization) and necrosis of neurons in all areas of the brain studied (frontal cortex, hippocampus, striatum and olfactory tubercle), showing a similar injury profile. In the group treated with 200 mg/kg policosanol swelling and necrosis were significantly reduced when compared with the control group. In another experimental model, comparison between groups showed that the brain water content of control gerbils (N = 15) was significantly higher after 15 min of clamping and 4 h of recirculation than in sham-operated animals (N = 13), whereas policosanol (200 mg/kg) (N = 19) significantly reduced the edema compared with the control group, with a cerebral water content identical to that of the sham-operated animals. cAMP levels in the brain of control-ligated Mongolian gerbils (N = 8) were significantly lower than those of sham-operated animals (N = 10). The policosanol-treated group (N = 10) showed significantly higher cAMP levels (2.68 pmol/g of tissue) than the positive control (1.91 pmol/g of tissue) and similar to those of non-ligated gerbils (2.97 pmol/g of tissue). In conclusion, our results show an anti-ischemic effect of policosanol administered after induction of cerebral ischemia, in two different experimental models in Mongolian gerbils, suggesting a possible therapeutic effect in cerebral vascular disorders.  (+info)

Definition of Stearyl alcohol in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Stearyl alcohol? Meaning of Stearyl alcohol as a legal term. What does Stearyl alcohol mean in law?
Expression of alcohol-forming fatty acyl-CoA reductases in E. coli can result in the biosynthesis of fatty alcohols from endogenous E. coli fatty acids, but the levels were quite low [19]. To improve the production of fatty alcohols, Steen et al. carried out a further genetic modification of E. coli, and achieved an increased titer (~60 mg/L) of the medium chain fatty alcohols (C12 or C14 alcohols) [3]. In their strategy, they employed thioesterases with different substrate specificities to tailor the composition of the FFAs, and used the aldehyde-forming fatty acyl-CoA reductase Acr1 for the conversion of fatty acyl-CoAs to fatty aldehydes. The synthesized fatty aldehydes can be further converted to fatty alcohols by an unknown alcohol dehydrogenase/aldehyde reductase of E. coli [6].. However, Steen et al. just obtained a small quantity of C16/18 alcohol, though they used the thioesterase TesA, which was capable of yielding a large proportion of C16/18 FFA [3]. As aforementioned, expression of ...
The global fatty alcohols market features a largely consolidated landscape, which in the coming years will increasingly shape the competitive dynamics of the market, notes Transparency Market Research (TMR). Prominent players in the global fatty alcohols market consider expanding their product portfolios as a key strategy to consolidate their positions.. Several of them are also focusing on expanding their regional footprints in order to get stronghold over the global fatty alcohols market. In particular, numerous chemical manufacturers are shifting their attention to new revenue streams in Asia Pacific where, they intend to gain from the availability of cheap raw materials, observes TMR.. Leading players in the global fatty alcohols market are VVF LLC, Kuala Lumpur Kepong Berhad (KLK), Musim Mas Holdings, Wilmar International Ltd., and Sasol Limited.. The global fatty alcohols market is forecast to rise at a CAGR of 5.1% during 2015-2023. By the end of this period, the global market is ...
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Source Naturals Policosanol, part of the Cholesterol Rescue™ family of products, is a blend of compounds isolated from natural plant waxes. Policosanol contains several long-chain fatty alcohols, including octacosanol, hexacosanol and triacontanol. Animal and in vitro research has shown that these compounds may support the cardiovascular system and inhibit lipid peroxidation as well as support macrophage activity. Coenzyme Q10 has been added to promote adequate levels of this important nutrient. Research indicates that CoQ10 levels in the body may be lowered by compounds that work on the same metabolic pathway as policosanol. CoQ10 supports the cardiovascular system and cellular energy production.
Policosanol normalizes cholesterol levels as well as or better than drugs, without any of their side-effects. Its efficacy and safety have been proven in numerous clinical trials in the U.S. and it has been used by millions of people in other countries.. Policosanol can lower LDL cholesterol by as much as 20% and raise protective HDL cholesterol by 10%. This compares favorably with cholesterol-lowering drugs which have the drawback of side-effects such as liver dysfunction and muscle atrophy. Policosanol works by blocking the synthesis of cholesterol but its exact mechanism of action is not known.. Another action of policosanol is reducing the proliferation of cells. Healthy arteries are lined with a smooth layer of cells so that blood can race through with no resistance. One of the features of diseased arteries is that this layer becomes thicker and overgrown with cells. As the artery narrows, blood flow slows down or is blocked completely.. Policosanol is a natural supplement made from sugar ...
CIR Safety Review:. Based on the similarity of the structures of these six ingredients, the CIR Expert Panel determined that safety data on Stearyl Heptanoate and palmitic acid and stearic acid were sufficient to support the safety of Stearyl Heptanoate, Stearyl Caprylate, Stearyl Palmitate, Stearyl Stearate, Stearyl Behenate and Stearyl Olivate.. The CIR Expert Panel reviewed safety data on Stearyl Heptanoate indicating the potential for mild skin irritation. It was not a sensitizer. Undiluted Stearyl Heptanoate was an eye irritant, but a 1.5% solution produced no effects. Mutagenesis assays (bacteria and micronucleus test) were negative. Clinical data showed no evidence of irritation or sensitization or ...
1. Arruzazabala ML, Molina V, Carbajal D et al: Effect of policosanol on platelet aggregation in type II hypercholesterolemic patients. Tissue Reactions 1998; 20(4):119-124. 2. Stusser R, Batista J, Padron B et al: Long-term therapy with policosanol improves treadmill exercise-ECG testing performance of coronary heart disease patients. Int J Clin Pharmacol Ther 1998; 36(9):469-473. 3. Valdes S, Arruzazabala ML, Fernandez L et al: Effect of policosanol on platelet aggregation in healthy volunteers. Int J Clin Pharmacol Res 1996; 16(2-3):67-72. 4. Batista J, Stusser R, Saez F et al: Effect of policosanol on hyperlipidemia and coronary heart disease in middle-aged patients. A 14-month pilot study. Int J Clin Pharmacol Ther 1996; 34(3):134-137. 5. Castano G, Tula L, Canetti M et al: Effects of policosanol in hypertensive patients with type II hypercholesterolemia. Curr Ther Res 1996; 57(9):691-695. 6. Canetti M, Moreira M, Mas R et al: A two-year study on the efficacy and tolerability of policosanol ...
Stress Induced Insomnia alleviated by Octacosanol from Clinical News - VHFILM on Vimeo. Stress Induced Insomnia alleviated by Octacosanol We review the public citation title: Cannot sleep due to stress? Here is the cure in which researchers discover this plant constituent can help restore normal sleep by possibly lowering corticosterone levels. Citation: Octacosanol…
Alcohols, C20-30 (even numbered), is a UVCB substance that comprises several linear long chain alcohols, predominantly tetracosan-1-ol (C24), hexacosan-1-ol (C26) and octacosan-1-ol (C28). Together, these constituents make up approximately 70% of the composition of Alcohols, C20 -30 (even numbered). Other constituents include, to a much lesser extent, secondary long chain alcohols and complex mixtures of long chain carboxylate esters. On this basis, study data, where available, for each of the long chain alcohol constituents has been evaluated and considered together; this is consistent with the Category approach applied for Long Chain Alcohols (LCA) under REACH. Long chain alcohols are already classified as a category comprising straight and branched alcohols with predominant carbon numbers in the range of C6 to C22. As defined in the Read Across Justification Document section 13, data provided for this Category is representative of Alcohols, C20-30 (even numbered) and has been extended to ...
Finite energy resources and increased environmental concerns demand the development of sustainable and renewable approaches to the production of fuels, chemicals, and materials. Engineering microbial metabolic pathways to synthesize desired products is an attractive approach. With recent advances in genetic techniques and metabolic engineering methodologies, various engineered microbes have been developed to produce an array of chemicals derived from inexpensive and renewable substrates [1, 2]. Target molecules are typically designed to replace or mimic those obtained from petroleum or other non-renewable sources [3, 4]. Among these chemicals, long-chain fatty alcohols (LCFLs) in the range of C12-C18 have numerous applications as fuels, emollients, plasticizers, thickeners, and detergents [5-7]. At the industrial scale, LCFLs are currently produced either through hydrogenation of pretreated natural fats and oils (oleochemicals) or hydroformylation of petrochemicals (e.g. crude oil, natural gas) ...
Surface freezing was studied in dry and hydrated octadecanol:tetradecanol (C[sub 18]OH:C[sub 14]OH) mixtures, using surface tension and synchrotron x-ray surface diffraction techniques. Even small amounts of admixed C[sub 18]OH were found to induce surface freezing in C[sub 14]OH which does not exhibit this effect when pure. The phase diagram of the bulk was measured by calorimetry and bulk x-ray diffraction. Upon increasing the bulk mole fraction of C[sub 18]OH (φ) a sharp increase in the bulk supercooling occurs at φ ≈ 0.4 in dry mixtures, while no supercooling was observed for the hydrated mixtures. A simple thermodynamical model based on the theory of s-regular mixtures is shown to account well for the dependence of the surface freezing onset temperature of both dry and hydrated mixtures, and the hydrated bulks freezing temperature on φ. Only a phenomenological description exists for the dry bulks phase diagram. This study is expected to provide a baseline for the general ...
Lydicamycin belongs to a novel structural class with highly selective antibiotic activity. Recent research has shown that lydicamycin and the related metabolites, TPU-0037A and TPU-0037C, are highly active against MRSA. Lydicamycin is also closely related to BN 4515N which was isolated from a strain of Microtetraspora as a neuritogenic agent ...
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About Fatty Alcohols Market Fatty alcohols are alcohols derived from natural fats and oils present in plants and animals. These are derived from fatty acids and ...
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NOW Policosanol is a blend of long-chain fatty alcohols (LCFA) derived from sugar cane, a superior source of these natural plant waxes. Studies indicate that these plant waxes may influence healthy cholesterol metabolism. This formula also includes herbs
NOW Policosanol is a blend of long-chain fatty alcohols (LCFA) derived from sugar cane, a superior source of these natural plant waxes. Non-clinical studies have surmised that the
Learn more about Policosanol at Doctors Hospital of Augusta Supplement Forms/Alternate Names: 1-Octacosanol N-Octacosanol Octacosanol Alcohol Octacosanol Wheat ...
Learn more about Policosanol at Medical City Dallas Supplement Forms/Alternate Names: 1-Octacosanol N-Octacosanol Octacosanol Alcohol Octacosanol Wheat ...
For those who are in need of additional cholesterol lowering support or who need to get off statin medication due to the above health concerns, Policosanol maybe your answer. Policosanol is a natural alternative to statin drugs and it is not known to create dangerous side effects. Policosanol is known to lower the dangerous LDL-Cholesterol molecule while raising HDL levels. A study performed by J Clinical Pharmacol in 1999 showed that policosanol significantly elevated the anti-inflammatory HDL and lowered LDL cholesterol oxidation. The study also indicated that 20 mg of policosanol per day for 7 day was as effective as aspirin in reducing platelet aggregation. Policosanol is a very safe supplement to use for extended periods of time. In a recent year-long study, older patients with hypercholesterolemia and hypertension were supplemented with policosanol and placebo. Side effects were greater in subjects taking the placebo (17.7%) versus policosanol (9.8%); and policosanol subjects had a ...
Producing bulk chemicals from renewable resources could reduce strong dependence on petroleum and the damage to the environment [1, 2]. As important chemicals with a billion-dollar market globally [3, 4], fatty alcohols have been widely used to produce detergents, emulsifiers, lubricants, cosmetics, and have the potential to be used as fuels [5]. Currently, fatty alcohols are produced in two ways. One is direct extraction from natural plant oils [6], and the other is chemical synthesis from petrochemical sources. These methods have limitations due to either competition with the food supply, environmental concerns [7], or fast depletion of fossil sources [8].. Recently, with the development of metabolic engineering and synthetic biology, microbial production of fatty alcohols from renewable feedstock has been achieved successfully in both Escherichia coli [4, 9] and Saccharomyces cerevisiae [3, 10]. So far, the highest titer of fatty alcohols produced was 1.95 [11] and 1.1 g/L [10] by E. coli and ...
TY - JOUR. T1 - Radical carboxylations of iodoalkanes and saturated alcohols using carbon monoxide. AU - Ryu, Ilhyong. PY - 2001/12/1. Y1 - 2001/12/1. N2 - This review covers two radical carboxylation methods using carbon monoxide, both of which were developed by our group. The first method, atom transfer carbonylation, converts alkyl iodides into carboxylic acid esters or amides and the second method, remote carboxylation, converts saturated alcohols into δ-lactones. Both methods rely upon radical carbonylation chemistry to introduce carbon monoxide, but the key steps are conceptually different. The first method utilizes an atom transfer reaction from an alkyl iodide to an acyl radical leading to an acyl iodide and the latter employs a one-electron oxidation reaction to convert an acyl radical into an acyl cation. The iodine atom transfer carbonylation process is reversible and therefore highly inefficient unless it is performed in concert with an ionic system to shift the equilibrium in the ...
Serving Size: 1 cap Servings per container: 60 Policosanol 10 mg ther ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide. Directions: Take two caps daily or as directred by a health care professional.
There was no significant dose dependence in LDL reduction from baseline to 12 weeks with placebo compared with the 4 policosanol dose groups (mean change -8.1% for placebo, -5.2% for 10 mg, -5.1% for 20 mg, -2.0% for 40 mg, and -8.3% for 80 mg; p=0.30 for dose-dependence). Likewise, there was no difference in other lipid parameters for placebo vs policosanol, including 12 week HDL (49 mg/dl for placebo, 53 mg/dl for 10 mg, 56 mg/dl for 20 mg, 52 md/dl for 40 mg, and 54 mg/dl for 80 mg) and total cholesterol (257, 276, 271, 270, and 274 mg/dl, respectively). There was no difference in adverse events between placebo and the policosanol groups (at least one adverse event: 28% with placebo, 21% with 10 mg, 37% with 20 mg, 37% with 40 mg, and 34% with 80 mg).. ...
Abstract We designed a series of hydrophobic hydrogels(HA-gels) through micellar copolymerization with acrylamide(AM) as hydrophilic monomer, a little amount of fatty alcohol polyoxyethylene acrylate(AEO-AC-n-m: n is the amount of carbon chain, m is the amount of PEG chain, n, m=10, 5; 13, 5; 13, 10) as hydrophobic monomer, and potassium thiosulfate(KPS) as initiator in sodium dodecyl sulfate(SDS) aqueous solution. The straight HA-gels prepared by AEO-AC-13-5 with straight carbon chain, possess uniform network structure and higher mechanical properties and can maintain their shapes in still water for 180 d. Conversely, the branched HA-gels synthesized by AEO-AC-10-5, AEO-AC-13-10 with various branched carbon chains, show relatively weak mechanical properties and degrade in water within 60 d. More specifically, the maximum broken stress of straight HA-gels is almost 4-5 times higher than branched HA-gels under the same constraints. On the basis of the neo-Hookean equation of the rubber ...
Dyes, Pigments Emulsifiers, Biodegradable Surfactants, Hydroxy Acetone, C11 Fatty Alcohols. Dyes, Pigments Emulsifiers, Biodegradable Surfactants.
Univar Solutions offers a full line of straight chain primary fatty alcohols, from as few as 8 carbons to as many as 22 as well as custom blends. They are commonly referred to as Short Chain (Carbon Chain < 10), Mid-Cut, and Long Chain (Carbon Chain > 18).
Indonesia will appeal the WorldTrade Organizations ruling in favour of European Unionanti-dumping duties on the export of certain fatty alcohols fromthe country, the trade ministry said on Friday.
Combination of chemical and electron-impact ionisation with GC x GC-qMS for characterization of fatty alcohol alkoxylate polymers in the low-molecular-weight range up to 700 ...
Chinas demand for Fatty Alcohol has grown at a fast pace in the past decade. In the next decade, both production and demand will continue to grow. The
Cetearyl alcohol (also known as cetostearyl alcohol and cetylstearyl alcohol) is a blend of cetyl and stearyl alcohols that we can use at up to 25% in our creations. It can be a 30% to 70% cetyl alcohol to stearyl alcohol or 30% to 70% stearyl alcohol to cetyl alcohol, but you might find 50-50 from some manufacturers. (I have no idea which version I have, but it looks a lot like Lanette O, which is 50-50.) It has an HLB of 15.5 and is used as a thickener. Its melting point is 49˚C to 58˚C. Its also saturated, so it will have a long shelf life ...
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
ResearchMoz recently published a market analysis report on the global keyword market using effective, reliable, and systematic research methodologies.
policosanol is a chemical acquired from sugar cane and different assets, policosanol is used for plenty conditions, but so far, there isnt always...
Source Naturals Policosanol Cholesterol Complex Bio-Aligned 60 tablet Policosanol Cholesterol Complex , part of the Cholesterol Rescue (TM) family of products, is a Bio-A...
Source Naturals Policosanol, part of the Cholesterol Rescue family of products, is a blend of compounds isolated from natural plant waxes. Policosanol contains
Nutritional supplement policosanol does not lower cholesterol levels A new study suggests that use of the nutritional supplement policosanol does not
United Kingdoms best source to buy Source Naturals Policosanol 20 mg - 60 Tablets at the lowest price. Read Policosanol 20 mg reviews, side effects, coupons and more from eVitamins. Fast, reliable shipping to United Kingdom
It may not be safe for breastfeeding women to use policosanol. This eMedTV page explains that no studies have been done on policosanol and breastfeeding, so it is not known if the supplement passes through breast milk or if it would cause problems.
Jarrow Formulas® Ultra Policosanols provides long-chain fatty alcohols that have been shown to support healthy cholesterol metabolism. Lecithin is important in the emulsification of fats for the enhanced absorption of fat-soluble nutrients, and is rich in phosphatidylcholine, a critical component of cellular membranes. Lecithin and medium chain triglycerides (MCTs) have been added to this formula to improve the absorption of the policosanols.
Effect of Gingerol on Cisplatin-Induced Pica Analogous to Emesis Via Modulating Expressions of Dopamine 2 Receptor, Dopamine Transporter and Tyrosine Hydroxylase in the Vomiting Model of ...
Cleanse and purify the hairs condition. Ingredients:. Water/Eau, Cetyl Alcohol, Stearamidopropyl Dimethylamine, Stearyl Alcohol, Quaternium-18, Cetearul Alcohol, Polsorbate 60, Bensul Alcohol, Phenoxyethanol, Fragrance/Parfum,Hydroxypropyl Guar, Bis-Aminopropyl Dimethicone, Oleyl Alcohol,Glyceryl Stearate, Methylparaben, Propylparaben, EDTA, Citric Acid, Hydrolyzed Silk, Simmondsia Chinensis (Jojoba) Seed Oil, Oryza Sativa (Rice) Bran Oil. ...
Sigma-Aldrich offers Aldrich-421529, Zonyl® FTS fluorotelomer intermediate for your research needs. Find product specific information including CAS, MSDS, protocols and references.
The House Republicans proposed bill to extend the Terrorism Risk Insurance Act (TRIA), set to expire at the end of this year, is encouraging, but there are also concerns, insurance industry experts say.. Representative Randy Neugebauer (R-Texas) introduced the TRIA Reform Act of 2014 on June 17, which would modify and extend TRIA. TRIA provides a government backstop for insurers and reinsurers in the event of a catastrophic terrorist attack. The proposed bill would extend the program for five years and make insurers more active participants in the market, according to American Banker. The proposed bill also distinguishes attacks that are nuclear, chemical, biological or radiological (NBCR) from other terrorist attacks and increases the industrys cost for conventional attacks.. Earlier in June, the Senate Banking Committee approved a bill that would extend TRIA for seven years, increase insurers co-pay for all attacks from 15% to 20% after a deductible, and increase the threshold for ...
Shop for Kroger® Docosanol Cold Sore/Fever Blister Treatment Cream at King Soopers. Find quality products to add to your Shopping List or order online for Delivery or Pickup.
Offers Fatty Amines Ethoxylate, OAA series based Oleyl Amine Ethoxylate, CAA series based on Coco Amine, SAA series based on Stearyl Amine by manufacturer and exporter of Surfactants, Oilfield Chemicals, cosmetic waxes and specialty chemicals, Rimpro India, Mehsana, India.
The Global Fluorotelomers Market is expected to reach USD 539.3 million by 2020, according to a new study by Grand View Research, Inc. Increased use of fluorotelomers in fire fighting foams and textiles is expected to drive demand over the next six years. The market is still in the nascent stage and is expected to gain significant share over the forecast period on account of substitution of other flurocarbons.. These products are preferred on account of their non toxic nature and the fact that they do not bio-accumulate in animals. Fluorotelomer alcohols such as TEOH-4 and TEOH-6 were the largest consumed product segment in 2013 and accounted for over 30% of global consumption. Fluorotelomer iodide is expected to be the fastest growing product segment at an estimated CAGR of 13.1% from 2014 to 2020.. Full Research Report on Global Fluorotelomers Market Analysis ...
The degradation of C14 linear alcohol in sediments was determined in two studies conducted in accordance with OECD 314 test method and using radiolabelled (14C) test substance. After 92 days, 76.5% mineralisation to CO2 was obtained using sediment from Ohio River near Cincinnati, Ohio area (Federle T W and Itrich N R, 2010a). After 149 days, 83.6% mineralisation to CO2 was obtained using Lytle Creek sediments from Wilmington, Ohio (Federle T W and Itrich N R, 2010b). A similar study is also available for an analogous saturated alcohol (described below). In another study, using activated sludge and radiolabelled (14C) test substance, 76.7% mineralisation of C14 to CO2 after 48 h was determined in accordance with OECD 314B (Federle, 2005). It is notable that significant technical difficulties were encountered during method development for a recent study of adsorption/desorption (OECD 106, Wildlife, 2015), with the structurally analogous substance decan-1-ol (CAS 112-30-1), using natural standard ...

No data available that match "fatty alcohols"

No data available that match "fatty alcohols"

  • Most fatty alcohols in nature are found as waxes which are esters with fatty acids and fatty alcohols. (
  • In the 1930s catalytic hydrogenation was commercialized, which allowed the conversion of fatty acid esters, typically tallow, to the alcohols. (
  • The process involves the transesterification of the triglycerides to give methyl esters which are then hydrogenated to produce the fatty alcohols. (
  • citation needed] Wax esters are hydrolyzed by a bile salt-dependent pancreatic esterase, releasing long-chain alcohols and fatty acids that are absorbed in the gastrointestinal tract. (
  • Furthermore, it has been shown that the wax synthase gene is located on the X chromosome, the expression of which lead to the formation of wax monoesters from straight chain, saturated, unsaturated, and polyunsaturated fatty alcohols and acids and that the formation of wax esters in mammals involves a two step biosynthetic pathway involving fatty acyl-CoA reductase and wax synthase enzymes. (
  • The enzymes produced by X-linked genes AWAT1 and AWAT2 have been shown to esterify long chain alcohols to produce wax esters and is most predominantly expressed in skin. (
  • The invention relates to the utilization of fatty materials with substantial free fatty acid content in the production of biodiesel by the use of microbial enzymes that are effective in a solvent-free process for the production of esters of fatty acids and C 1 -C 3 alkyl alcohols. (
  • In the present discussion, Tony O'Lenick recruits Ismail Walele of Phoenix Chemical to explain the differences between fatty alcohols, fatty acids and esters. (
  • Production of fatty acid esters from stearic, oleic, and palmitic acids and short-chain alcohols (methanol, ethanol, propanol, and butanol) for the production of biodiesel was investigated in this work. (
  • The present invention provides a novel approach for the preparation of fatty alcohol esters of α-hydroxy carboxylic acids. (
  • Wax esters ( WEs ) are oxoesters of long-chain fatty acids esterified with long-chain fatty alcohols. (
  • In some taxa small amounts of wax esters were detected with alcohol moieties similar to those of the dominant Arctic copepods. (
  • The occurrence of intact wax esters, as well as the wax ester typical fatty acids 20:1(n-9) and 22:l(n-l 1), also suggested ingestion of large herbivorous copepods. (
  • Arabidopsis cer4 mutants exhibit major decreases in stem primary alcohols and wax esters, and slightly elevated levels of aldehydes, alkanes, secondary alcohols, and ketones. (
  • Cetyl Esters Wax-which is produced from coconuts is classified as another form of fatty alcohols used to create better stability in a cream or lotion. (
  • Fatty Acids, Alcohols, and Esters - can they be natural? (
  • We love using plant-derived esters as they don't feel as oily on the skin like other types of emollients and fatty ingredients + they absorb wonderfully. (
  • Unsaturated fatty acids have one or more carbon-carbon double bond in the molecule. (
  • Saturated and unsaturated fatty acids are different in their form, as unsaturated fatty acids have one or more alkenyl functional group along the chain. (
  • Unsaturated fatty acids such as oleic acid can show two of their distinct forms (isomers), i.e. cis and trans forms. (
  • Fatty alcohols (or long-chain alcohols) are usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4-6 carbons to as many as 22-26, derived from natural fats and oils. (
  • Scientists have also identified, characterized, and shown the WSD1 gene in Arabidopsis thaliana to encode a bifunctional wax ester synthase/diacylglycerol acyltransferase enzyme that is embedded in the ER membrane, in which the wax synthase portion is critical to wax ester synthesis using long-chain and very-long-chain primary alcohols with C fatty acids. (
  • Fatty alcohols (or long-chain alcohols) are usually high-molecular-weight, straight-chain primary alcohols, derived from natural fats and oils. (
  • Alcohols are alkanes with a hydroxyl group on the terminal carbon, which makes them primary alcohols. (
  • N amed after inventor M. Guerbet, Guerbet alcohols are alkaline condensation reaction products of primary alcohols. (
  • Expression of CER4 cDNA in yeast (Saccharomyces cerevisiae) resulted in the accumulation of C24: 0 and C26: 0 primary alcohols. (
  • These data indicate that CER4 is an alcohol-forming FAR that has specificity for very-long-chain fatty acids and is responsible for the synthesis of primary alcohols in the epidermal cells of aerial tissues and in roots. (
  • Three endoplasmic reticulum-associated fatty acyl-coenzyme a reductases were involved in the production of primary alcohols in hexaploid wheat ( Triticum aestivum L. (
  • Fatty alcohols are mainly used in the production of detergents and surfactants. (
  • Due to their amphipathic nature, fatty alcohols behave as nonionic surfactants. (
  • This is positively influencing the demand for fatty alcohols as they are used to produce surfactants for detergent applications. (
  • Fatty alcohols, due to their amphipatic nature, act as non-ionic surfactants /co-surfactants. (
  • In addition to smoothing, fatty alcohols can also be found in many shampoos and conditioners to thicken it as well as to serve as emulsion stabilizers and nonionic surfactants. (
  • The reactor used enabled the continuous removal of water and esterification with hydrated alcohol (ethanol 95%) without affecting the original activity of the clay. (
  • A biomarker for recent alcohol consumption, phosphatidyl ethanol (PEth) was sampled. (
  • Effect of ethanol and thermally oxidized sunflower oil ingestion on phospholipid fatty acid composition of rat liver: protective role of Cuminum cyminum L. (
  • A fatty alcohol ( meaning it is an alcohol which comes from fat) does not behave like a 'real alcohol' for example ethanol or propanol as it has numerous benefits to skin care products and the skin itself. (
  • In addition to isopropyl and ethyl alcohols being included in this category, others include: isobutane, propyl alcohol, propanol, alcohol denat, SD alcohol 40, SD alcohol and ethanol. (
  • For ethanol found in alcoholic drinks, see Alcohol (drug) . (
  • [2] The term alcohol originally referred to the primary alcohol ethanol (ethyl alcohol), which is used as a drug and is the main alcohol present in alcoholic drinks . (
  • An important class of alcohols, of which methanol and ethanol are the simplest members, includes all compounds for which the general formula is C n H 2n+1 OH. (
  • The meaning of alcohol was extended to distilled substances in general, and then narrowed to ethanol, when "spirits" was a synonym for hard liquor . (
  • The word's meaning became restricted to "spirit of wine" (the chemical known today as ethanol ) in the 18th century and was extended to the class of substances so-called as "alcohols" in modern chemistry after 1850. (
  • The term ethanol was invented in 1892, blending " ethane " with the "-ol" ending of "alcohol", which was generalized as a libfix . (
  • Production of medium-chain fatty acids can be performed via chain elongation, utilizing acetate and ethanol as main substrates. (
  • C. kluyveri is well known for its reversed β-oxidation metabolism, converting short chain fatty acids with ethanol into MCFA and hydrogen (Table 1 ). (
  • Harsh alcohols, including rubbing alcohol or ethanol, are extremely drying, but serve an antibacterial function. (
  • I wonder if most of this would fit better in ethanol , or does it apply to all alcohols? (
  • It is my understanding that all alcohols would have similar effects, but I think you are right anyway since the only onw that is really consumed in any quantity is ethanol. (
  • We propose that such downstream mediators from CYP2E1 in association with ethanol-induced elevation of TNF1, homocysteine and ER stress activate lipogenic transcription factors and enzymes while decreasing activation of lipolytic transcription factors and enzymes, thereby resulting in fatty liver. (
  • Preliminary data in support of these hypotheses are the findings that ethanol-induced fatty liver is blunted in CYP2E1 knockout mice and restored in humanized CYP2E1 knockin mice. (
  • The ethanol-fed CYP2E1 knockin mice appear to be an effective ORAL model of alcohol-induced hepatotoxicity. (
  • AIM 2 is designed to evaluate pathways by which CYP2E1 contributes to alcohol-induced fatty liver, including assays of levels of transcription factors such as SREBP-1c and PPAR1, content of key and rate- limiting lipogenic and lipolytic enzymes;rates of fatty acid oxidation will be determined in the wild type, CYP2E1 knockout and CYP2E1 knockin mice fed ethanol or dextrose. (
  • We believe these experiments will provide molecular mechanisms by which CYP2E1 promotes ethanol-induced liver injury and fatty liver and may further the development of new therapeutic designs to treat or minimize progression of ethanol-induced liver injury, a stated goal of RFA-AA-006. (
  • Our central hypothesis is that chronic ethanol exposure alters the normal vesicle trafficking between lipid droplets and other membrane organelles in the hepatocyte, leading to fatty liver. (
  • Two different laboratories expert in alcohol induced liver damage and hepatocellular membrane-cytoskeletal dynamics will work in synergy to determine the functions of each of these organelles in regulating lipid droplet formation and metabolism under normal conditions and following ethanol exposure to mediate the progression of AFLD. (
  • We hypothesize that chronic ethanol exposure alters the normal vesicle trafficking between lipid droplets and Golgi, endosomes, and endoplasmic reticulum, leading to fatty liver and subsequently hepatocellular damage. (
  • These WEs are composed of very-long-chain (C20, C22, and C24) monounsaturated fatty acids and alcohols, and their physiological function is to serve as a primary storage reserve for postgerminative growth ( Miwa, 1971 ). (
  • Also, the trend of shifting preference from powdered detergents to liquid detergents has added to the growth of the global fatty alcohols market as a much higher quantity of surfactant is used to manufacture liquid-based detergents. (
  • The report provides actionable insights to improve source-to-contract cycle performance in the Global Fatty Alcohols Market. (
  • SpendEdge's report, Global Fatty Alcohols Market, provides up-to-date information about market shifts and potential risks, as well as in-depth knowledge of products and services, which can help in planning and in executing category management activities. (
  • The global fatty alcohols market is expected to post a CAGR of close to 5% during the period 2019-2023, according to the latest market research report by Technavio. (
  • Technavio has announced its latest market research report titled global fatty alcohols market 2019-2023. (
  • These factors are expected to boost the growth of the global fatty alcohols market during the forecast period. (
  • This market report segments the global fatty alcohols market by application (cleaning products, personal care, lubricants, and others) and geography (APAC, EMEA, and the Americas). (
  • The clinicopathological profile of Indian patients with nonalcoholic fatty liver disease (NAFLD) is different from that in the West. (
  • Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and it has gradually become the main disease burden in the world. (
  • Fatty liver or steatosis is a common finding in several liver diseases, most notably non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) but is also seen more frequently in chronic hepatitis C virus (HCV) related liver disease than would be predicted by simple concurrence of the two diseases. (
  • Background and aim: Moderate alcohol consumption has been associated with a lower risk of disease severity in non-alcoholic fatty liver disease (NAFLD). (
  • We evaluated the impact of lifetime alcohol consumption on fibrosis severity in NAFLD. (
  • Methods: We prospectively enrolled 120 subjects with biopsy-proven NAFLD and through detailed questionnaires examined lifetime alcohol consumption, diet and physical activity. (
  • Conclusion: Lifetime alcohol consumption with up to 13 units per week is associated with lower fibrosis stage in NAFLD. (
  • Epidemiological studies suggested that the prevalence and the disease severity of non-alcoholic fatty liver disease (NAFLD) are lower for people who drink modest amounts of alcohol than those who are abstainers. (
  • Accordingly, NAFLD and non-alcoholic steatohepatitis (NASH) prevalence, liver enzymes and inflammatory markers were lower in subjects who took modest amounts of alcohol than those who are abstainers (table 1). (
  • Since its first description in 1980, NAFLD has been conceived as a different entity from alcohol-related fatty liver disease (ALD), despite that, both diseases have an overlap in the pathophysiology, share genetic-epigenetic factors, and frequently coexist. (
  • Distinction between NAFLD and ALD is based on the amount of consumed alcohol, which has been arbitrarily established. (
  • In this context, a proposal of positive criteria for NAFLD diagnosis not considering exclusion of alcohol consumption as a prerequisite criterion for diagnosis had emerged, recognizing the possibility of a dual etiology of fatty liver in some individuals. (
  • The impact of moderate alcohol use on the severity of NAFLD is ill-defined. (
  • Some studies suggest protective effects in moderate doses, but current evidence shows that there is no safe threshold for alcohol consumption for NAFLD. (
  • In this review, we summarize the overlapping pathophysiology of NAFLD and ALD, the current data on alcohol consumption in patients with NAFLD, and the effects of metabolic dysfunction and overweight in ALD. (
  • Nonalcoholic fatty liver disease (NAFLD) is defined by hepatic steatosis in the presence of alcohol intake within safe limits, defined by guidelines of scientific associations (usually 20 g or 2 units/day in women, 30 g or 3 units in men). (
  • Finally, the negative effects of the calorie content of alcohol on dietary restriction and weight loss, the pivotal intervention to reduce NAFLD burden, should be considered. (
  • In summary, the policy of counseling NAFLD patients for alcohol abstinence should be maintained. (
  • Nonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. (
  • Nonalcoholic fatty liver disease (NAFLD), a common liver condition, is characterized by excessive accumulation of hepatic fat in the absence of significant alcohol consumption, and has been associated with insulin resistance (IR) [ 1 - 4 ]. (
  • Non-alcoholic fatty liver disease (NAFLD) and alcohol related fatty liver disease (AFLD) both represent a spectrum of liver disease severity from hepatic steatosis to fibrosis and cirrhosis. (
  • It is often not possible to distinguish between NAFLD and AFLD on examination of liver histology, consequently, differentiation between NAFLD and AFLD is heavily reliant on a history of alcohol consumption. (
  • Age, smoking, alcohol consumption and sex appear to influence the risk of mortality in NAFLD or AFLD. (
  • Expression of the fatty alcohol-producing enzyme fatty acyl-CoA reductase alleviated the growth defect caused by deletion of hexadecenal dehydrogenase encoding genes (HFD1 and HFD4) in Y. lipolytica. (
  • Below are the list of possible Alcohol-forming fatty acyl-CoA reductase products. (
  • Very long-chain fatty alcohols (VLCFA), obtained from plant waxes and beeswax have been reported to lower plasma cholesterol in humans. (
  • Studies of fatty alcohol metabolism in fibroblasts suggest that very long-chain fatty alcohols, fatty aldehydes, and fatty acids are reversibly inter-converted in a fatty alcohol cycle. (
  • The antibacterial activity against Staphylococcus aureus of long-chain fatty alcohols was investigated, with a focus on normal alcohols. (
  • 1-Dodecanol and 1-tridecanol had the highest antibacterial activity among the long-chain fatty alcohols tested, but had no membrane-damaging activity. (
  • Consequently, it appears that not only the antibacterial activity but also the mode of action of long-chain fatty alcohols might be determined by the length of the aliphatic carbon chain. (
  • fatty acids (myristate, palmitate, oleate, linoleate and linolinate), long chain fatty alcohols (C 22 -C 32 -Table 2) and alkanes in the blades. (
  • Upon germination, WE hydrolysis releases very-long-chain fatty alcohols, which must be oxidized to fatty acids by the sequential action of a fatty alcohol oxidase ( FAO ) and a fatty aldehyde dehydrogenase ( FADH ) before they can be β-oxidized. (
  • The intrinsic structural properties of branched long-chain fatty alcohols (BLFLs) in the range of C12 to C18 make them more suitable as diesel fuel replacements and for other industrial applications than their straight-chain counterparts. (
  • While microbial production of straight long-chain fatty alcohols has been achieved, biosynthesis of BLFLs has never been reported. (
  • These two developments opened the way to synthetic fatty alcohols. (
  • Synthetic fatty alcohols are mainly derived from petrochemical sources such as ethylene. (
  • Synthetic fatty alcohols are produced from ethylene using the Ziegler reaction, which yields a chemically identical linear primary alcohol with an even numbered carbon chain. (
  • Consumption of alcohol produces galanin, and galanin promotes the consumption of alcohol. (
  • This observation helps confirm the conclusion that galanin affects alcohol consumption and also suggests the possibility of someday creating a drug that blocks galanin in order to fight alcoholism . (
  • Factors such as declining petroleum supplies and the rising use of plant oil for human consumption have been restricting the development of fatty oils. (
  • Excess alcohol consumption can lead to a gradual scarring of the liver and eventually may lead to cirrhosis and abnormalities of liver function. (
  • Prevention of further damage, if possible, is the first step and we will encourage lifestyle changes if your liver disease is related to alcohol consumption to try to reduce the pressure on the liver. (
  • We can provide patients with a tailored set of investigations to assess for liver damage and can support patients in their efforts to reduce their alcohol consumption. (
  • This stage usually produces no symptoms and gets better if alcohol consumption is reduced. (
  • The cornerstone of the treatment of alcohol-related liver disease is a sustained reduction in alcohol consumption. (
  • We can assist patients to identify ways to reduce their alcohol consumption and if necessary make recommendations and onward referrals to allied specialists in this field to help. (
  • In addition, it seems unlikely that the risk of fatty liver can be reduced by the discontinuation and/or reduction of alcohol consumption alone. (
  • Nevertheless, the evidence is still inconclusive because some recently published studies 1 showed that modest alcohol consumption (MAC) increases hepatic fat without increasing the risk of advanced fibrosis. (
  • Their objective was to assess whether alcohol consumption is associated with concentrations of very-long-chain ''marine'' (e.g., fish oil) n 3 FAs both in plasma and in red blood cell membranes. (
  • Professor R Curtis Ellison comments: 'An increase in omega-3 (n-3) fatty acids, found to be associated with alcohol consumption, could be important from at least two perspectives: it could be a new mechanism by which alcohol or wine could reduce the risk of cardiovascular disease, and it could be a way for people who do not like fish to get these important fatty acids. (
  • there was a much less consistent relation between the consumption of beer or spirits and levels of n-3 fatty acids. (
  • Disease burden and costs from excess alcohol consumption, obesity, and viral hepatitis: fourth report of the Lancet Standing Commission on Liver Disease in the UK. (
  • fatty liver Copper deficit reduces alcohol consumption and fatty liver the risk of developing childhood leukemia. (
  • Another alcohol consumption and fatty liver disease hepatitis does not provide a cure. (
  • Presentation to the circulation and were very limited amounts of Omega-3 fatty acids you have to redo the medicine for this drug increased restingly enough after partaking of fish and proper disposal of human being hard of hearing cultures fatty liver liver alcohol consumption and behavior needs of the dire effects obese children to the chest pain abnormal elders about 0. (
  • It works with nitric oxide helping fight bacterial and fatty liver liver alcohol consumption digestive cavity. (
  • It's generally associated with binge alcohol consumption. (
  • A fatty alcohol containing 30 carbons and 1 double bond. (
  • As with fatty acids, they are often referred to generically by the number of carbon atoms in the molecule, such as "a C12 alcohol", that is an alcohol having 12 carbons, for example dodecanol. (
  • These are derived from fatty acids and have an even number of carbons. (
  • Generally, alcohols are normal alcohols from natural fats and oils, meaning that they all have an even number of carbons. (
  • Saturated fatty acids have all carbons with a full quota of hydrogens. (
  • The recombinant enzyme accepts saturated and mono-unsaturated fatty acyl-CoAs of 16 to 22 carbons. (
  • Univar Solutions offers a full line of straight chain primary fatty alcohols, from as few as 8 carbons to as many as 22 as well as custom blends. (
  • The problem with short-chain alcohols is that their structure is similar to that of water molecules so when they have less than 3 carbons in their tail, they mix in water very easily. (
  • They are referred to as fatty alcohols because the higher number of carbons (their carbon chains usually have 12 to 20 per molecule), makes them oilier, hence the term fatty alcohols. (
  • In addition to stearyl and cetyl alcohols, other fatty ones include: behenyl alcohol, myristyl alcohol, lauryl alcohol and cetearyl alcohol. (
  • Products Ethoxylated lauryl Alcohol Product Description Inquiry If you have any questions,feedback or comments, please fill out the form below and we will reply you back as soon as possible. (
  • An aliphatic alcohol consisting of a chain of 8 to 22 carbon atoms. (
  • chain carbon group, such as fatty alcohols or alkylbenzene. (
  • Fatty alcohols usually have an even number of carbon atoms and a single alcohol group (-OH) attached to the terminal carbon. (
  • In general, wax synthases naturally accept acyl groups with carbon chain lengths of C16 or C18 and linear alcohols with carbon chain lengths ranging from C12 to C20. (
  • Staphylococcus aureus;fatty alcohols;antibacterial activity;length of carbon chain;K+ ion leakage. (
  • Some alcohols have their hydroxyl group on the c-chain, excluding the terminal primary carbon and making them secondary alcohols. (
  • The production of fatty alcohols from fatty acids yields normal-chain alcohols wherein the -OH group attaches to the terminal carbon. (
  • Branched alcohols can be mono-methyl branched or multi-carbon chained on the side at any or specific interior carbon of the main carbon chain. (
  • They are primary, alpha branched dimeric alcohols and are 100% defined branched at the second carbon position. (
  • Oxo alcohols and iso-alcohols are alpha-olefin based and are approximately 50% branched at the second carbon position. (
  • Fatty acids are organic acids comprised of carbon chains with a carboxyl group at the end. (
  • A cyclic C19:0 fatty acid and farnesol were attributed to this group that was also actively fixing carbon. (
  • Natural fatty alcohols have an even number of carbon atoms with a single functional alcohol group (-OH) attached at the first carbon. (
  • In chemistry , alcohol is an organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. (
  • This co-culture poses an alternative way to produce medium-chain fatty acids and higher alcohols from carbon monoxide or syngas and the process can be regarded as an integration of syngas fermentation and chain elongation in one growth vessel. (
  • Alcohols are organic compounds that contain one or more hydroxyl (OH) groups (an oxygen and hydrogen atom) bound to carbon atoms. (
  • Alcohols are characterized by their solubility in both water and oil, which is determined by the length of the molecule's carbon chain. (
  • With a short carbon chain, an alcohol has greater solubility in water, which means it will evaporate quickly, taking water with it, while an alcohol with a long carbon chain will hinder evaporation and hold water down. (
  • Under a few specialized circumstances, such as unique chemical configuration, some short carbon chains alcohols actually display moisturizing properties instead of the drying characteristic common to small alcohols. (
  • Fatty alcohols are alcohols derived from natural fats and oils present in plants and animals. (
  • Fatty alcohols are aliphatic alcohols derived from natural fats and oils originating in plants and animals. (
  • 18). Natural fatty alcohols are derived from natural fats and oils by hydrogenating the corresponding fatty methyl ester and subsequent fractionation. (
  • The difference in classification depends on the actual structure of a given alcohol with short-chain alcohols such as isopropyl and ethyl alcohol causing damage and fatty ones such as stearyl and cetyl helping your hair. (
  • If short-chain alcohols dry out the hair, why do manufacturers use them in the first place? (
  • But the problem with relying on short-chain alcohols to quickly dry your hair is that when the alcohol evaporates, it takes some of the water (and natural oils like sebum) with it, leaving your strands dry. (
  • Unlike short-chain alcohols, fatty ones serve a healthy purpose in products. (
  • Some commercially important fatty alcohols are lauryl, stearyl, and oleyl alcohols. (
  • So if you see stearyl or cetyl alcohol in the ingredients for a hair product, you should choose it but avoid those that contain isopropyl or ethyl alcohol. (
  • Stearyl alcohol acts as an emollient and an emulsifier. (
  • Lanette 18 is a stearyl alcohol that is used for viscosity regulation in cosmetic oil-in-water emulsions, on account of its consis. (
  • A brain chemical that stokes hunger for food and fat also triggers thirst for alcohol and may play a role in chronic drinking, according to a study led by Princeton University scientists. (
  • In animals given galanin and access to alcohol, the role of the chemical appeared to be subverted: it boosted alcohol intake instead of eating. (
  • In enzymology, a long-chain-alcohol O-fatty-acyltransferase (EC is an enzyme that catalyzes the chemical reaction acyl-CoA + a long-chain alcohol ⇌ {\displaystyle \rightleftharpoons } CoA + a long-chain ester Thus, the two substrates of this enzyme are acyl-CoA and long-chain alcohol, whereas its two products are CoA and long-chain ester. (
  • Find a wide selection of higher fatty acid alcohols at Spectrum Chemical including products like undecyl alcohol. (
  • Spectrum specializes in providing the top higher fatty acid alcohols if you do not see the product, grade, or form of the ingredient you require, just contact our chemical specialist at 800-772-8786. (
  • These differentiating physico-chemical properties of branched chain alcohols make them immensely important in the synthesis and derivatization into cosmetics and personal care emollients. (
  • Fatty alcohols (FAs) are major components of surface lipids (waxes) and can act as surface-active organic aerosols in the atmosphere, influencing chemical reactions, particle lifetimes, and the formation of cloud droplets and ice nuclei. (
  • When our liver tries to break down alcohol, the resulting chemical reaction can damage its cells. (
  • 2.SO3.Na Chemical Name:Sodium Lauryl Ether Sulphate(SLES) 70% Sodium Lauryl Ethere Sulfate Sodium Ethoxylated Alkyl Sulfate Sodium Polyoxyethyl;ene Fatty Alcohol Sulfate Abbr. (
  • Mechanical Strength and Swelling Behavior of Fatty Alcohol Polyoxyethylene Acrylate Hydrophobic Associated Hydrogels[J]. Chemical Journal of Chinese Universities, 2016, 37(9): 1744-1749. (
  • abstract = "Fatty alcohols are widely used in various applications within a diverse set of industries, such as the soap and detergent industry, the personal care, and cosmetics industry, as well as the food industry. (
  • The saturated Guerbet alcohols or branched iso alcohols offer fluidity and also thermal stability and oxidation stability. (
  • Coexpression of jojoba FAO and FADH in Arabidopsis enhanced the in vivo rate of fatty alcohol oxidation more than 4-fold. (
  • Taken together, our data suggest that jojoba FAO and FADH constitute the very-long-chain fatty alcohol oxidation pathway that is likely to be necessary for efficient WE mobilization following seed germination. (
  • What they now show is that this receptor-ligand pair can also mediate hepatic steatosis in both viral hepatitis and in response to alcohol. (
  • Alcoholic liver disease encompasses the hepatic alterations leading to fatty liver, hepatitis, and fibrosis or cirrhosis. (
  • Formally known as hepatic steatosis, fatty liver disease (FLD) occurs as fat builds up in this vital organ and alcohol contributes to this accumulation. (
  • Procoagulant imbalance in patients with non-alcoholic fatty liver disease. (
  • Significant non-alcoholic fatty liver disease is found in non-diabetic, pre-obese Chinese in Singapore. (
  • Predictors reflecting the pathological severity of non-alcoholic fatty liver disease: comprehensive study of clinical and immunohistochemical findings in younger Asian patients. (
  • Finally, because TNF-α plays an important role in alcoholic fatty liver disease, they investigated whether alcohol could sensitise mice to the effects of TRAIL. (
  • Moderate Alcohol Intake in Non-Alcoholic Fatty Liver Disease: To Drink or Not to Drink? (
  • The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. (
  • There are usually no symptoms with alcoholic fatty liver disease. (
  • Alcoholic fatty liver disease (AFLD) is marked by the aberrant accumulation of intracellular fatty acids in hepatocytes and can progress to hepatitis, fibrosis, cirrhosis, and liver failure. (
  • The researchers plan to explore further the role of galanin and other neuropeptides in alcohol use, as well as the role of fat intake and metabolism on alcohol intake. (
  • In conclusion, through this multi-omics study, we uncovered some effects of fatty alcohol production on the host metabolism. (
  • The liver is the primary storage site for excess iron and this iron increases inflammation that occurs during alcohol metabolism. (
  • Lower iron (when it is elevated) and alcohol metabolism from moderate drinking will not inflame your liver like what occurs when iron is elevated. (
  • Normal fatty alcohol metabolism is poorly understood and no information is known about the clinical effects of altered fatty alcohol metabolism. (
  • A long-term objective of this proposal is to understand normal fatty alcohol metabolism and how FAO deficiency may lead to the clinical phenotype of SLS. (
  • We propose to investigate fatty alcohol metabolism in cultured skin fibroblasts from normal and SLS subjects to understand the deranged fatty alcohol metabolism in SLS. (
  • To uderstand fatty alcohol metabolism in tissues with quite different FAO activities, metabolic studies will be performed in rat hepatocytes and brain tissue slices using radiochemnical and enzymatic techniques. (
  • These studies will provide fundamental information about normal fatty alcohol metabolism and the deranged fatty alcohol metabolism in SLS. (
  • There is also direct damage to cell membranes from free-radicals that are produced from alcohol metabolism. (
  • The potential use of n-alkanes, long-chain alcohols and long-chain fatty acids as diet composition markers: indoor validation with sheep and herbage species from the rangeland of Inner Mongolia of China. (
  • To investigate the potential use of n-alkanes (alkanes), long-chain alcohols (alcohols) and long-chain fatty acids (acids) for estimating the diet composition of sheep, in a feeding trial. (
  • The systematic name of this enzyme class is acyl-CoA:long-chain-alcohol O-acyltransferase. (
  • One of the primary endocannabinoid neurotransmitters, anandamide, is degraded by fatty acid amide hydrolase, an enzyme with a functional genetic polymorphism (FAAH C385A, rs324420) that has been linked to problem drug and alcohol use in humans. (
  • The acyl-ACP and alcohol-producing modules were also extensively optimized to balance enzyme expression level and ratio, resulting in a 6.5-fold improvement in BLFL titers. (
  • These are not 'alcohols' like ethyl alcohol but the result of combining fatty acids with hydrogen, creating a slightly waxy texture. (
  • SD-alcohol 40 is a blend of ethyl alcohol (drinking alcohol), specially denatured to make it unfit to drink. (
  • According to industry standards and regulations, this means that the product does not contain ethyl alcohol, which is known for its harsh, drying effects. (
  • Nutriol HFT also contains undenatured ethyl alcohol, an ingredient that improves the delivery of the beneficial powders in the product. (
  • Fatty alcohols can be used in cosmetic formulations as emulsifiers, emollients and thickeners. (
  • Fatty acids are used as emulsifiers (they bind water with lipids), thickeners and emollients. (
  • Natural fatty alcohols are a very good vegan alternative to beeswax and great emulsifiers for water + oil formulations (creams, moisturizers, lotions). (
  • The molecule must also contain a hydrophilic (water-soluble) group, such as ―COONa, or a sulfo group, such as ―OSO 3 Na or ―SO 3 Na (such as in fatty alcohol sulfate or alkylbenzene sulfonate), or a long ethylene oxide chain in nonionic synthetic detergents. (
  • This process affords even-numbered alcohols: Al(C2H5)3 + 18 C2H4 → Al(C14H29)3 Al(C14H29)3 + 3⁄2 O2 + 3⁄2 H2O → 3 HOC14H29 + 1⁄2 Al2O3 Alternatively ethylene can be oligomerized to give mixtures of alkenes, which are subjected to hydroformylation, this process affording odd-numbered aldehyde, which is subsequently hydrogenated. (
  • When they inserted these bacteria into mice, the mice also developed fatty liver. (
  • In one form of the invention, the target fatty alcohol ester of α-hydroxy carboxylic acid is produced by converting a lower alkyl ester of α-hydroxy carboxylic acid into a fatty alcohol ester of α-hydroxy carboxylic acid via alcoholysis (i.e., transesterification). (
  • 1. A method for synthesizing a fatty alcohol ester of α-hydroxy carboxylic acid, comprising: converting a lower alkyl ester of α-hydroxy carboxylic acid into a fatty alcohol ester of α-hydroxy carboxylic acid via transesterification, wherein the transesterification process is an equilibrium reaction that is shifted in the desired direction to produce the desired product. (
  • This report studies the global Higher Alcohol Fatty Acid Ester Complex market status and forecast, categorizes the global Higher Alcohol Fatty Acid Ester Complex market size (value & volume) by manufacturers, type, application, and region. (
  • Table 2) Dry mass, total lipid and wax ester content as well as fatty acid and fatty alcohol composition of Arctic deep-sea copepods during the expedition with Maria S. Merian MSM02/4. (
  • The global Higher Alcohol Fatty Acid Ester Complex market is segmented by company, region (country), by Type, and by Application . (
  • Players, stakeholders, and other participants in the global Higher Alcohol Fatty Acid Ester Complex market will be able to gain the upper hand as they use the report as a powerful resource. (
  • The Higher Alcohol Fatty Acid Ester Complex market is analysed and market size information is provided by regions (countries). (
  • Segment by Application , the Higher Alcohol Fatty Acid Ester Complex market is segmented into North America, Europe, China, Japan, Southeast Asia, India and Other Regions. (
  • Cancer of the liver is becoming more common due to such factors as hepatitis C, as well as another condition called non-alcohol fatty liver disease. (
  • Alcohol hepatitis requires urgent medical therapy to prevent acute deterioration in liver function. (
  • Elevated iron has also been implicated in fatty liver disease and NASH (non-alcoholic steato-hepatitis) in particular, and iron reduction through phlebotomy or blood donation has been shown to help resolve this. (
  • If an alcholic shows fatty liver disease, it can then progress to hepatitis and then cirrhosis. (
  • It's not true that fatty liver disease will always progress in this fashion, and sometimes patients who drink a lot of alcohol have hepatitis but not the cirrhosis. (
  • Stearic Acid -is one of the most common, naturally occurring fatty acids. (
  • it is best to use wholesome oils, which contain a balanced ratio of naturally occurring fatty acids. (
  • This phenotype suggested that CER4 encoded an alcohol-forming fatty acyl-coenzyme A reductase (FAR). (
  • NADPH-dependent alcohol-forming fatty acyl-coenzyme A reductase that catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (
  • Fatty alcohols are also prepared from petrochemical sources. (
  • Cuticular waxes are complex mixtures of very-long-chain fatty acids and their derivatives. (
  • Some alcohols, like panthenol and propylene glycol, enhance a product's moisturizing qualities because they are humectants, binding water to the skin. (
  • Nu Skin employs fatty alcohols such as panthenol, propylene glycol, cetyl alcohol, butylene glycol, and cetearyl alcohol that have proven beneficial moisturizing properties. (
  • As per Technavio, the advent of biosynthetic fatty alcohols, will have a positive impact on the market and contribute to its growth significantly over the forecast period. (
  • Bio-based production of medium-chain fatty acids (MCFA), such as butyrate and caproate, is of potential interest because they can serve as commodity chemicals. (
  • In fact, these alcohols are only one type in a very large group of chemicals that have many qualities and functions. (
  • The alcohols are obtained from the triglycerides (fatty acid triesters), which form the bulk of the oil. (
  • In this study, we aimed to obtain a better understanding of how fatty alcohol biosynthesis impacts the host organism, baker's yeast Saccharomyces cerevisiae or oleaginous yeast Yarrowia lipolytica. (
  • What is the role of alcohol abstinence in the treatment of fatty liver disease? (
  • Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease. (
  • De novo nonalcoholic fatty liver disease after liver transplantation. (
  • The natural history of nonalcoholic fatty liver disease: a population-based cohort study. (
  • Long term prognosis of fatty liver: risk of chronic liver disease and death. (
  • Susceptibility to alcohol-related liver disease can also run in families. (
  • however, there was some suggestion of an increase in fatty liver disease with higher volume of alcohol consumed per day. (
  • Moderate drinkers had lower levels of obesity than did non-drinkers, and both obesity and metabolic abnormalities were positively associated with fatty liver disease. (
  • It all started with a patient suffering from severe fatty liver and autobrewery syndrome , an unusual disease where the body produces alcohol. (
  • An epidemic of fatty liver is currently spreading across the world, and those affected also have an increased risk of type 2 diabetes, cardiovascular disease, and liver cancer. (
  • Rajagopalan, Rukkumani 2014-04-06 00:00:00 Alcoholism is a broad term used for problems related to alcohol, medically considered as disease, specifically an addictive illness, abuse, and dependence. (
  • The authors of a recent study state that because high dietary and blood n 3 (omega-3) fatty acids (FAs) are protective against coronary heart disease and sudden cardiac death, the alcohol-associated increase in blood n 3 FAs could be considered an original mechanism of alcohol's cardioprotective effect. (
  • Data strongly indicate that higher levels of n-3 fatty acids are associated with less heart disease, especially reducing the risk of sudden death. (
  • We revised the literature on the effects of modest alcohol intake on disease burden. (
  • a detrimental effect of modest alcohol drinking is similarly observed in liver disease of viral etiology. (
  • EASL Clinical Practice Guidelines: Management of alcohol-related liver disease. (
  • Levene AP, Goldin RD. The epidemiology, pathogenesis and histopathology of fatty liver disease. (
  • Younossi Z, Henry L. Contribution of alcoholic and nonalcoholic fatty liver disease to the burden of liver-related morbidity and mortality. (
  • How Does Alcohol Cause Liver Disease is an understandable suggestion due to the reason that it is related to How Fatty Liver Can Be Cured, How Fatty Liver Can Be Cured, and How Long Can You Live With Liver Failure Without Treatment. (
  • Major diseases like Alzheimer's disease as well as abusing alcohol is a huge factor is dramatic. (
  • What Is Fatty Liver Disease? (
  • Numerous epidemiological studies have found an association between moderate alcohol intake and reduced coronary heart disease risk and also mortality rates. (
  • Drinking alcohol can increase your risk of developing liver disease and cause irreparable damage to this very important part of your body. (
  • In fact, alcohol is a major cause of the 25% increase in deaths from liver disease in England over the last decade (from 9,231 in 2001 to 11,575 in 2009) 2 . (
  • Overall, alcohol-related liver disease accounts for well over a third (37%) of liver disease deaths. (
  • The advice on this page is specific to alcohol-related liver disease. (
  • Alcohol-related liver disease can be prevented if you understand the impact excessive alcohol drinking can have on your liver and take-steps to control the amount you drink. (
  • But all the research shows that the more alcohol you drink, the more likely you are to develop liver disease. (
  • But if you don't change your drinking pattern, that fatty liver is the first stage of developing liver disease. (
  • Stopping drinking will help reduce damage and the progression of alcohol-related liver disease. (
  • The only cause of alcohol-related fatty liver disease is alcohol. (
  • This is obvious to medical experts because those who drink more than two to three drinks daily for long periods of time will often have fatty liver disease - and the fatty liver disease may disappear when the person gives up alcohol. (
  • Alcohol-related fatty liver disease is not the only liver problem caused by alcohol. (
  • Alcohol abuse and alcohol-induced liver disease are a major health concern in the US and worldwide. (
  • PUBLIC HEALTH RELEVANCE: The goal of this proposal is to examine how impairments and alterations in trafficking and targeting of lipid droplets (LD) to specific organelles influences LD accumulation in steatosis and contributes to alcohol-induced fatty liver disease (AFLD). (
  • The study showed that rats injected with galanin, a natural signaling agent in the brain, chose to drink increasing quantities of alcohol even while consuming normal amounts of food and water. (
  • If carbs from our food cause fatty liver, then a diet with minimal amounts of carbs might improve fatty liver. (
  • High amounts of the fatty acid 16: l(n-7), typical of diatoms, were found in different taxa from the northeast Greenland shelf. (
  • Dairy cows and fresh manure have the potential to emit considerable amounts of alcohols and CH 4 and research is needed to determine effective mitigation. (
  • Consuming large amounts of alcohol on a regular basis can lead to fat buildup in the cells. (
  • In low amounts alcohols are not toxic. (
  • Recombinant jojoba FAO and FADH proteins are active on very-long-chain fatty alcohol and fatty aldehyde substrates, respectively, and have biochemical properties consistent with those previously reported in jojoba cotyledons. (
  • Application of long-chain alcohols as faecal markers to estimate diet composition of horses and cattle fed with herbaceous and woody species. (
  • The potential use of long-chain alcohols and fatty acids as diet composition markers: factors influencing faecal recovery rates and diet composition estimates in sheep. (
  • Both alcohols increased over time, coinciding with increasing accumulation of manure on the chamber floor. (
  • The pathogenesis of SLS will be investigate in rat feeding studies to establish whether tissue fatty alcohol accumulation leads to biochemical and clinical changes characteristic of SLS. (
  • Many naturally-derived emollients are in reality plant oils that go through a reaction (between an organic acid and an alcohol or hydrogen or glycerin). (
  • Knowing that dimethiconols or silanols condense under acid or alkaline catalysis, a study was undertaken to determine if these compounds could be successfully ethoxylated under conditions similar to those used to ethoxylate fatty alcohols and acids. (
  • Sodium Lauryl Ether Sulfate / Sodium Laureth Sulfate (SLES/AES) Synonyms: (C10-C16) Alcohol ethoxylate sulfated sodium salt, Sodium Laureth Sulphate, sodium lauryl ether sulfate, SLES, AES CAS No: 68585-34-2 EINECS No: 209-553. (
  • Effect of glycine on tissue fatty acid composition in an experimental model of alcohol-induced hepatotoxicity. (
  • This concept is expected to emerge as one of the major alternatives for the production of fatty alcohols. (
  • The bacteria convert carbs from food into alcohol, which in turn causes production of fat in the liver. (
  • This study shows that a production of alcohol in the intestines, caused by a high amount of carbs in the diet, may also contribute to the problem. (
  • The total world production of fatty alcohols is over 2 million tons with approximately equal parts derived from fossil oil and from plant oils or animal fats. (
  • Due to the environmental impact of these production methods, there is an interest in alternative methods for fatty alcohol production via microbial fermentation using cheap renewable feedstocks. (
  • The fatty alcohol-producing Y. lipolytica strain had a higher fatty alcohol production rate than an analogous S. cerevisiae strain. (
  • RNAseq analysis showed that fatty alcohol production triggered a cell wall stress response in S. cerevisiae. (
  • RNAseq analysis also showed that both nitrogen-depletion and fatty alcohol production have substantial effects on the expression of transporter encoding genes in Y. lipolytica. (
  • This knowledge can be used as guidance for further strain improvement towards the production of fatty alcohols. (
  • Because both processes require harsh reaction conditions and release harmful byproducts to the environment [ 11 ], microbial production of fatty alcohols from renewable sugars is a promising alternative. (
  • While it is possible to get the same results using a polymer, fatty alcohols are generally much cheaper, making production of these hair products more affordable. (
  • [6] In the twelfth century, recipes for the production of aqua ardens ("burning water", i.e., alcohol) by distilling wine with salt started to appear in a number of Latin works, and by the end of the thirteenth century it had become a widely known substance among Western European chemists. (
  • 1. The aim of the present study was to investigate the effect of the administration of glycine, a non-essential amino acid, on blood alcohol levels and tissue fatty acid composition in experimental rats. (
  • 3. Feeding alcohol significantly elevated the activities of serum aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatases (ALP) and gamma-glutamyl transpeptidase (GGT) and altered the liver and brain fatty acid composition compared with control rats. (
  • Subsequently, glycine supplementation to alcohol-fed rats significantly lowered the activities of serum AST, ALT, ALP, GGT and normalized the liver and brain fatty acid composition compared with untreated alcohol-fed rats. (
  • 4. Thus, the present study demonstrates that oral administration of glycine confers a significant protective effect against alcohol-induced hepatotoxicity by virtue of its ability to optimize the activities of serum AST, ALT, ALP and GGT, as well as the tissue fatty acid composition. (
  • Changes in fatty acid composition, decrease in phospholipids levels, and increase in PLA, PLC were observed in the diseased group. (
  • From the results obtained, we conclude that WG effectively protects the liver against alcohol and ΔPUFA-induced changes in fatty acid composition and preserves membrane integrity. (
  • An unusual fatty acid composition was found for most brittle stars, due to a ratio of the 18:1(n-9) and (n-7) fatty acid isomers below 1 with lowest ratios of 0.1. (
  • They differed in fatty acid composition and trophic level, indicating different food preferences. (
  • The research report on the Fatty Alcohol Polyoxyethylene Ether Market is a deep analysis of the market. (
  • The Fatty Alcohol Polyoxyethylene Ether Market research report offers an eight-year forecast. (
  • In conclusion, the Fatty Alcohol Polyoxyethylene Ether Market report is a reliable source for accessing the research data that is projected to exponentially accelerate your business. (
  • Technical Data Sheet Thixome S-9 comb-polyether INCI Name ● ACRYLATES/C10-30 ALKYL ACRYLATE/FATTY ALCOHOL ● POLYOXYETHYLENE ETHER ● Macromolecular structureand has low foaming ability. (
  • The abundance of renewable resources for microbial growth is encouraging several researchers and vendors to increase their focus on the development of bio-synthesized fatty alcohols. (
  • Alcohols of microbial mats from Lake 2A on Kiritimati Island. (
  • Alcohol-Induced Fatty Liver and Injury in Humanized CYP2E1 Knockin Mice. (
  • ALKONAT® 1214 CL and ALKONAT® 1214 CH differ by the content of Cetyl Alcohol (C16), with higher contents for ALKONAT® 1214 CH. The main markets of the ALKONAT® line are those of cosmetics and cleaners, in addition to other industrial applications. (
  • ALKONAT® 1618 C30 and ALKONAT® 1618 C50 also differ in their content of Cetyl Alcohol, with higher contents for ALKONAT® 1618 C50. (
  • Cetyl Alcohol - is a fatty alcohol that is produced by heating up coconut oil and palm oil with a strong base (in our case, with an ingredient that causes soap to saponify or become hard). (
  • Spotting strange and synthetic-like ingredient names like Cetyl Alcohol or Isopropyl palmitate that don't sound right? (