The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.
A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
A condition of low alertness or cognitive impairment, usually associated with prolonged mental activities or stress.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Muscular contractions characterized by increase in tension without change in length.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
The time span between the beginning of physical activity by an individual and the termination because of exhaustion.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Conditions characterized by disturbances of usual sleep patterns or behaviors. Sleep disorders may be divided into three major categories: DYSSOMNIAS (i.e. disorders characterized by insomnia or hypersomnia), PARASOMNIAS (abnormal sleep behaviors), and sleep disorders secondary to medical or psychiatric disorders. (From Thorpy, Sleep Disorders Medicine, 1994, p187)
A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
Recording of the changes in electric potential of muscle by means of surface or needle electrodes.
Term generally used to describe complaints related to refractive error, ocular muscle imbalance, including pain or aching around the eyes, burning and itchiness of the eyelids, ocular fatigue, and headaches.
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
The rotational force about an axis that is equal to the product of a force times the distance from the axis where the force is applied.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
Elements of limited time intervals, contributing to particular results or situations.
The musculofibrous partition that separates the THORACIC CAVITY from the ABDOMINAL CAVITY. Contraction of the diaphragm increases the volume of the thoracic cavity aiding INHALATION.
The amount of force generated by MUSCLE CONTRACTION. Muscle strength can be measured during isometric, isotonic, or isokinetic contraction, either manually or using a device such as a MUSCLE STRENGTH DYNAMOMETER.
Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.
A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical stability has been attained in patients with a prior history of symptomatic poliomyelitis. Clinical features include new muscular weakness and atrophy of the limbs, bulbar innervated musculature, and muscles of respiration, combined with excessive fatigue, joint pain, and reduced stamina. The process is marked by slow progression and periods of stabilization. (From Ann NY Acad Sci 1995 May 25;753:68-80)
Use of electric potential or currents to elicit biological responses.
A mental disorder characterized by chronic fatigue and concomitant physiologic symptoms.
Physiological or psychological effects of periods of work which may be fixed or flexible such as flexitime, work shifts, and rotating shifts.
Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.
The quadriceps femoris. A collective name of the four-headed skeletal muscle of the thigh, comprised of the rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis.
A readily reversible suspension of sensorimotor interaction with the environment, usually associated with recumbency and immobility.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.
Fractures due to the strain caused by repetitive exercise. They are thought to arise from a combination of MUSCLE FATIGUE and bone failure, and occur in situations where BONE REMODELING predominates over repair. The most common sites of stress fractures are the METATARSUS; FIBULA; TIBIA; and FEMORAL NECK.
Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
A region of the lower extremity immediately surrounding and including the KNEE JOINT.
Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.
A regimen or plan of physical activities designed and prescribed for specific therapeutic goals. Its purpose is to restore normal musculoskeletal function or to reduce pain caused by diseases or injuries.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
The performance of the basic activities of self care, such as dressing, ambulation, or eating.
The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Intra-aural contraction of tensor tympani and stapedius in response to sound.
A type of non-ionizing radiation in which energy is transmitted through solid, liquid, or gas as compression waves. Sound (acoustic or sonic) radiation with frequencies above the audible range is classified as ultrasonic. Sound radiation below the audible range is classified as infrasonic.
The narrow passage way that conducts the sound collected by the EAR AURICLE to the TYMPANIC MEMBRANE.
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
The measurement of frequency or oscillation changes.

Perioperative growth hormone treatment and functional outcome after major abdominal surgery: a randomized, double-blind, controlled study. (1/2703)

OBJECTIVE: To evaluate short- and long-term effects of perioperative human growth hormone (hGH) treatment on physical performance and fatigue in younger patients undergoing a major abdominal operation in a normal postoperative regimen with oral nutrition. SUMMARY BACKGROUND DATA: Muscle wasting and functional impairment follow major abdominal surgery. METHODS: Twenty-four patients with ulcerative colitis undergoing ileoanal J-pouch surgery were randomized to hGH (12 IU/day) or placebo treatment from 2 days before to 7 days after surgery. Measurements were performed 2 days before and 10, 30, and 90 days after surgery. RESULTS: The total muscle strength of four limb muscle groups was reduced by 7.6% in the hGH group and by 17.1% in the placebo group at postoperative day 10 compared with baseline values. There was also a significant difference between treatment groups in total muscle strength at day 30, and at the 90-day follow-up total muscle strength was equal to baseline values in the hGH group, but still significantly 5.9% below in the placebo group. The work capacity decreased by approximately 20% at day 10 after surgery, with no significant difference between treatment groups. Both groups were equally fatigued at day 10 after surgery, but at day 30 and 90 the hGH patients were less fatigued than the placebo patients. During the treatment period, patients receiving hGH had reduced loss of limb lean tissue mass, and 3 months after surgery the hGH patients had regained more lean tissue mass than placebo patients. CONCLUSIONS: Perioperative hGH treatment of younger patients undergoing major abdominal surgery preserved limb lean tissue mass, increased postoperative muscular strength, and reduced long-term postoperative fatigue.  (+info)

Carbon disulphide absorption during xanthate reagent mixing in a gold mine concentrator. (2/2703)

A xanthate reagent mixer at a gold mine concentrator was exposed to carbon disulphide by extensive skin contamination with xanthate powder and solution during the reagent mixing process. Absorption of carbon disulphide was confirmed by the detection of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA). Drager colorimetric tube testing during subsequent mixing recorded a maximum concentration of at least 60 ppm carbon disulphide. An illness consisting of predominantly gastrointestinal symptoms began 20 h after the exposure. Although this may have been due to carbon disulphide toxicity this is by no means certain. The need for engineering controls, impervious protective clothing and full-face respirators with particulate and organic vapour cartridges is discussed. This episode occurred at another mine site, unrelated to Mount Isa Mines Limited.  (+info)

The role of capsaicin-sensitive muscle afferents in fatigue-induced modulation of the monosynaptic reflex in the rat. (3/2703)

1. The role of group III and IV afferent fibres of the lateral gastrocnemious muscle (LG) in modulating the homonymous monosynaptic reflex was investigated during muscle fatigue in spinalized rats. 2. Muscle fatigue was induced by a series of increasing tetanic electrical stimuli (85 Hz, 600 ms) delivered to the LG muscle nerve. Series consisted of increasing train numbers from 1 to 60. 3. Potentials from the spinal cord LG motor pool and from the ventral root were recorded in response to proprioceptive afferent stimulation and analysed before and during tetanic muscle activations. Both the pre- and postsynaptic waves showed an initial enhancement and, after a '12-train' series, an increasing inhibition. 4. The enhancement of the responses to muscle fatiguing stimulation disappeared after L3-L6 dorsal root section, while a partial reflex inhibition was still present. Conversely, after section of the corresponding ventral root, there was only a reduction in the inhibitory effect. 5. The monosynaptic reflex was also studied in animals in which a large number of group III and IV muscle afferents were eliminated by injecting capsaicin (10 mM) into the LG muscle. As a result of capsaicin treatment, the fatigue-induced inhibition of the pre- and postsynaptic waves disappeared, while the response enhancement remained. 6. We concluded that the monosynaptic reflex inhibition, but not the enhancement, was mediated by those group III and IV muscle afferents that are sensitive to the toxic action of capsaicin. The afferents that are responsible for the response enhancement enter the spinal cord through the dorsal root, while those responsible for the inhibition enter the spinal cord through both the ventral and dorsal roots.  (+info)

Effect of working hours on cardiovascular-autonomic nervous functions in engineers in an electronics manufacturing company. (4/2703)

A field survey of 147 engineers (23-49 years) in an electronics manufacturing company was conducted to investigate the effect of working hours on cardiovascular-autonomic nervous functions (urinary catecholamines, heart rate variability and blood pressure). The subjects were divided into 3 groups by age: 23-29 (n = 49), 30-39 (n = 74) and 40-49 (n = 24) year groups. Subjects in each age group were further divided into shorter (SWH) and longer (LWH) working hour subgroups according to the median of weekly working hours. In the 30-39 year group, urinary noradrenaline in the afternoon for LWH was significantly lower than that for SWH and a similar tendency was found in the LF/HF ratio of heart rate variability at rest. Because these two autonomic nervous indices are related to sympathetic nervous activity, the findings suggested that sympathetic nervous activity for LWH was lower than that for SWH in the 30-39 year group. Furthermore, there were significant relationships both between long working hours and short sleeping hours, and between short sleeping hours and high complaint rates of "drowsiness and dullness" in the morning in this age group. Summarizing these results, it appeared that long working hours might lower sympathetic nervous activity due to chronic sleep deprivation.  (+info)

Investigating fatigue of less than 6 months' duration. Guidelines for family physicians. (5/2703)

OBJECTIVE: To develop an evidence-based systematic approach to assessment of adult patients who present to family physicians complaining of fatigue of less than 6 months' duration. The guidelines present investigative options, making explicit what should be considered in all cases and what should be considered only in specific situations. They aim to provide physicians with an approach that, to the extent possible, is based on evidence so that time and cost are minimized and detection and management of the cause of the fatigue are optimized. QUALITY OF EVIDENCE: MEDLINE was searched from 1966 to 1997 using the key words "family practice" and "fatigue." Articles about chronic fatigue syndrome were excluded. Articles with level 3 evidence were found, but no randomized trials, cohort studies, or case-control studies were found. Articles looking specifically at the epidemiology, demographics, investigations, and diagnoses of patients with fatigue were chosen. Articles based on studies at referral and specialty centres were given less weight than those based on studies in family physicians' offices. MAIN MESSAGE: Adherence to these guidelines will decrease the cost of investigating the symptom of fatigue and optimize diagnosis and management. This needs to be proved in practice, however, and with research that produces level 1 and 2 evidence. CONCLUSIONS: Adults presenting with fatigue of less than 6 months' duration should be assessed for psychosocial causes and should have a focused history and physical examination to determine whether further investigations should be done. The guidelines outline investigations to be considered. The elderly require special consideration. These guidelines have group validation, but they need to be tested by more physicians in various locations and types of practices.  (+info)

Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer. (6/2703)

PURPOSE: To evaluate the feasibility of administering topotecan in combination with paclitaxel and cisplatin without and with granulocyte colony-stimulating factor (G-CSF) support as first-line chemotherapy in women with incompletely resected stage III and stage IV ovarian carcinoma. PATIENTS AND METHODS: Starting doses were paclitaxel 110 mg/m2 administered over 24 hours (day 1), followed by cisplatin 50 mg/m2 over 3 hours (day 2) and topotecan 0.3 mg/m2/d over 30 minutes for 5 consecutive days (days 2 to 6). Treatment was repeated every 3 weeks. After encountering dose-limiting toxicities (DLTs) without G-CSF support, the maximum-tolerated dose was defined as 5 microg/kg of G-CSF subcutaneously starting on day 6. RESULTS: Twenty-one patients received a total of 116 courses at four different dose levels. The DLT was neutropenia. At the first dose level, all six patients experienced grade 4 myelosuppression. G-CSF support permitted further dose escalation of cisplatin and topotecan. Nonhematologic toxicities, primarily fatigue, nausea/vomiting, and neurosensory neuropathy, were observed but were generally mild. Of 15 patients assessable for response, nine had a complete response, four achieved a partial response, and two had stable disease. CONCLUSION: Neutropenia was the DLT of this combination of paclitaxel, cisplatin, and topotecan. The recommended phase II dose is paclitaxel 110 mg/m2 (day 1), followed by cisplatin 75 mg/m2 (day 2) and topotecan 0.3 mg/m2/d (days 2 to 6) with G-CSF support repeated every 3 weeks.  (+info)

Manganese sulfate-dependent glycosylation of endogenous glycoproteins in human skeletal muscle is catalyzed by a nonglucose 6-P-dependent glycogen synthase and not glycogenin. (7/2703)

Glycogenin, a Mn2+-dependent, self-glucosylating protein, is considered to catalyze the initial glucosyl transfer steps in glycogen biogenesis. To study the physiologic significance of this enzyme, measurements of glycogenin mediated glucose transfer to endogenous trichloroacetic acid precipitable material (protein-bound glycogen, i.e., glycoproteins) in human skeletal muscle were attempted. Although glycogenin protein was detected in muscle extracts, activity was not, even after exercise that resulted in marked glycogen depletion. Instead, a MnSO4-dependent glucose transfer to glycoproteins, inhibited by glycogen and UDP-pyridoxal (which do not affect glycogenin), and unaffected by CDP (a potent inhibitor of glycogenin), was consistently detected. MnSO4-dependent activity increased in concert with glycogen synthase fractional activity after prolonged exercise, and the MnSO4-dependent enzyme stimulated glucosylation of glycoproteins with molecular masses lower than those glucosylated by glucose 6-P-dependent glycogen synthase. Addition of purified glucose 6-P-dependent glycogen synthase to the muscle extract did not affect MnSO4-dependent glucose transfer, whereas glycogen synthase antibody completely abolished MnSO4-dependent activity. It is concluded that: (1) MnSO4-dependent glucose transfer to glycoproteins is catalyzed by a nonglucose 6-P-dependent form of glycogen synthase; (2) MnSO4-dependent glycogen synthase has a greater affinity for low molecular mass glycoproteins and may thus play a more important role than glucose 6-P-dependent glycogen synthase in the initial stages of glycogen biogenesis; and (3) glycogenin is generally inactive in human muscle in vivo.  (+info)

Fatigue in advanced cancer: a prospective controlled cross-sectional study. (8/2703)

Uncontrolled studies have reported that fatigue is a common symptom among patients with advanced cancer. It is also a frequent complaint among the general population. Simply asking cancer patients whether or not they feel fatigued does not distinguish between the 'background' level of this symptom in the community and any 'excess' arising as a result of illness. The aim of this study was to determine the prevalence of fatigue among palliative care inpatients in comparison with a control group of age and sex-matched volunteers without cancer. In addition, the correlates of fatigue were investigated. The prevalence of 'severe subjective fatigue' (defined as fatigue greater than that experienced by 95% of the control group) was found to be 75%. Patients were malnourished, had diminished muscle function and were suffering from a number of physical and mental symptoms. The severity of fatigue was unrelated to age, sex, diagnosis, presence or site of metastases, anaemia, dose of opioid or steroid, any of the haematological or biochemical indices (except urea), nutritional status, voluntary muscle function, or mood. A multivariate analysis found that fatigue severity was significantly associated with pain and dypnoea scores in the patients, and with the symptoms of anxiety and depression in the controls. The authors conclude that subjective fatigue is both prevalent and severe among patients with advanced cancer. The causes of this symptom remain obscure. Further work is required in order to determine if the associations reported between fatigue and pain and between fatigue and dyspnoea are causal or coincidental.  (+info)

Mendoza T, Wang XS, Cleeland CS, et al. The rapid assessment of fatigue severity in cancer patients: use of the Brief Fatigue Inventory. Cancer 85: 1186-1196, 1999.. Mendoza TR, Laudico AV, Wang XS, et al. Assessment of fatigue in cancer patients and community dwellers: validation study of the Filipino version of the Brief Fatigue Inventory. Oncology 79(1-2): 112-117, 2010.. Mystakidou K, Tsilika E, Parpa E, et al. Psychometric properties of the Brief Fatigue Inventory in Greek patients with advanced cancer. J Pain Symptom Manage 36(4): 367-373, 2008.. Lin CC, Chang AP, Chen ML, Cleeland CS, Mendoza TR, Wang XS. Validation of the Taiwanese Version of the Brief Fatigue Inventory. J Pain Symptom Manage 32(1): 52-59, 2006.. Yun YH, Wang XS, Lee JS, et al. Validation study of the Korean version of the Brief Fatigue Inventory. J Pain Symptom Manage 29(2): 165-172, 2005.. Wang XS, Hao XS, Wang Y, et al. Validation study of the Chinese version of the Brief Fatigue Inventory (BFI-C). J Pain Symptom ...
Cancer-related fatigue (CRF) is one of the most common symptoms experienced by cancer patients (CPs). The Brief Fatigue Inventory (BFI) is a reliable instrument to assess CRF in CPs. The aim of this s
Protracted treatment on intensive care unit (ICU) sets the patients at increased risk for the development of chronic critical illness (CCI). Muscular and cardio-respiratory deconditioning are common long-term sequelae, going along with a state of chronic fatigue. At present, findings regarding the frequency, long-term course, and associated factors of self-reported fatigue following ICU treatment of CCI patients are lacking. CCI patients with the diagnosis of critical illness polyneuropathy/myopathy (CIP/CIM) were assessed at three time points. Four weeks following the discharge from ICU at acute care hospital (t1), eligibility for study participation was asserted. Self-reported fatigue was measured using the Multidimensional Fatigue Inventory (MFI-20) via telephone contact at 3 (t2, n = 113) and 6 months (t3, n = 91) following discharge from ICU at acute care hospital. At both 3 and 6 months, nearly every second CCI patient showed clinically relevant fatigue symptoms (t2/t3: n = 53/n = 51, point
Cancer-related fatigue is a subjective symptom of fatigue that is experienced by nearly all cancer patients. Among patients receiving cancer treatment other than surgery, it is essentially universal. Fatigue is a normal and expected side effect of most forms of chemotherapy, radiation therapy, and biotherapy. On average, cancer-related fatigue is more severe, more distressing, and less likely to be relieved by rest than fatigue experienced by healthy people. It can range from mild to severe, and may be either temporary or a long-term effect. Fatigue may be a symptom of the cancer, or it may be the result of treatments for the cancer. The National Comprehensive Cancer Network defines cancer-related fatigue as a distressing persistent, subjective sense of physical, emotional and/or cognitive tiredness or exhaustion related to cancer or cancer treatment that is not proportional to recent activity and interferes with usual functioning. Cancer-related fatigue is a chronic fatigue (persistent ...
Background and objectives: To explore if intravenous iron isomaltoside (Monofer ®) leads to a better relief of fatigue than current treatment practice with oral iron in women suffering from severe fatigue after postpartum hemorrhage. Materials and methods: This is a subanalysis of a single-center, open-label, randomized controlled trial conducted in women suffering from postpartum hemorrhage. Participants were randomized 1:1 to 1200 mg iron isomaltoside or current treatment practice with oral iron. We measured fatigue by the Multidimensional Fatigue Inventory (MFI) and Edinburgh Postnatal Depression Scale, and determined hematological parameters. The subanalysis includes all participants with a high fatigue score (MFI physical fatigue score ,15) at inclusion. The primary endpoint was aggregated change in physical fatigue score from inclusion to 12 weeks postpartum with a predefined minimum clinically relevant difference of 1.8. The trial is registered at ClinicalTrials.gov (identifier: ...
Fatigue is a common problem among individuals with Parkinsons disease (PD). It may occur before the overt symptoms of bradykinesia, rigidity and tremor. Little is understood about how to measure fatigue in PD. Here we determined the dimensionality of the constructs of fatigue. Four recommended scales, the Fatigue Severity Scale, Functional Assessment of Chronic Illness Therapy-Fatigue, Parkinson Fatigue Scale and Visual Analog Fatigue Scale (VAFS) were tested against quality of life measures including cognition, depression, sleep, life orientation, physical activity and PD symptoms in 22 PD subjects and 15 caregivers. Fatigue was associated with many quality of life variables, with the PDQ-39 summary index showing the strongest association. PD subjects agreed more strongly than caregivers that they experienced higher levels of fatigue. 27% of PD subjects rated fatigue as one of their top three most bothersome symptoms. The constructs of fatigue was captured within one dimension which explained 67% of
ASCO Abstract Number: 9004. CHICAGO - Cancer-related fatigue is often a major problem for cancer patients, beginning at diagnosis, during treatment and after completing therapy. Researchers at Mayo Clinic and the North Central Cancer Treatment Group (NCCTG) recently completed a study testing methylphenidate in the treatment of cancer-related fatigue and found that, while it did not improve fatigue for a broad group of patients, the data did not rule out a benefit for those with stage III/IV cancer. Results of this NCCTG study, N05C7, will be presented on Sunday, June 6, 2010, at the American Society of Clinical Oncology annual meeting in Chicago.. VIDEO ALERT: Additional audio and video resources, including excerpts from an interview with Dr. Deb Barton is available on the Mayo Clinic News Blog.. Cancer-related fatigue can impact a patients ability to tolerate therapy and their overall quality of life, says Debra Barton, R.N., Ph.D., associate professor of oncology at Mayo Clinic in ...
SIG members first examined the subjective fatigue experience dimension of the Checklist Individual Strength (CIS20-R) [20], a well validated and widely used multidimensional self-report measure that aims to assess subjective experience of fatigue, concentration, motivation, and physical activity. Some SIG members expressed the view that the 8 items of the fatigue subscale seemed to evaluate peripheral or muscle fatigue consecutive to physical activity rather than central fatigue per se. Others were of the opinion that the subjective fatigue items appeared to have been devised for healthy people rather than for individuals with chronic neuromuscular conditions. In addition, SIG members expressed some concerns regarding the content validity of the fatigue subscale, most items seemingly focusing on physical fatigue and not sufficiently documenting aspects of mental fatigue or weariness that many patients typically feel upon morning awakening. Moreover, many items are not plausible for DM1. For ...
When sarcoidosis is in clinical remission, complaints of chronic fatigue often persist. The exact features of this post-inflammatory fatigue are unknown. This study assesses the severity of fatigue and the presence of fatigue-related symptoms in sarcoidosis-in-clinical-remission. Furthermore, we evaluate psychological distress, pain and patient-reported sleep quality, and record physical activity levels and muscle strength as objective assessments of fatigue. Lastly, we assess the severity of fatigue at a follow-up.. Methods: Seventy-five patients with sarcoidosis-in-clinical-remission were evaluated with the Checklist Individual Strength (fatigue), the SymptomChecklist-90 (psychological distress), the McGill Pain Questionnaire (pain), standardized interview (fatigue-related symptoms), sleep diary, accelerometer and muscle strength tests.. Results: Fatigue severity mean score in sarcoidosis patients in-clinical-remission was high (fatigue-severity score: 30.5±15.5), and fatigue-related symptoms ...
Cancer-related fatigue is a symptom with great implications for the quality of life of those that experience it. It is regarded as one of the most distressing symptoms that people with cancer develop. Its aetiology is complex, and although the mechanisms underlying fatigue have not been fully clarified it is evident that it is exacerbated by treatments intended to cure or palliate the disease. Patients at risk of cancer-related fatigue need access to information that will enable them to manage it effectively. There are a growing number of materials available to patients in different European countries on this topic, but it is unclear how useful patients find these. This study was undertaken to explore this through conducting focus groups with patients in the United Kingdom and Switzerland. One focus group was conducted in each country. Findings from these determined that individuals voiced common concerns: fatigue had not been addressed in the clinical setting - individuals surmised why this ...
Brief Fatigue Inventory (BFI) consist of 3 items that assess the severity of fatigue and 6 items that assess the impact of fatigue on daily functioning in a 10-points scale with 0 as no fatigue or does not interfere with daily functioning and 10 as bad fatigue or completely interferes. The scores for the six items were summed up to form a total interference score. The linear analogue scale of fatigue was a 10-points scale with 0 as no fatigue and 10 as bad fatigue. All scores were then transformed into 0 to 100 scale, with 100 as less fatigue/less interference. Change from baseline to week 4 was calculated by subtracting the baseline scores from the scores at week 4 ...
Change between Day 7 to Baseline in FACIT-F (Functional Assessment of Chronic illness Therapy-Fatigue) & FACT-G (Functional Assessment of Cancer Therapy-General) scores. Participants rate quality of life using FACT-G consisting of 33 questions with 5 domains assessing physical and social, emotional & functional well being & relationship with physician, remaining 5 assess extent to which each domain affects overall quality of life on 5-point scale from 0 (not at all) to 4 (very much); total score obtained by summing individual subscale scores (0-132). FACIT-F consists of 13 items where participants rate intensity of fatigue & its related symptoms on a scale of 0-4 from 0 not at all to 4 very much. The responses to FACIT fatigue questionnaire are each measured on 4‐point Likert scale with total score ranges from 0 to 52. High scores represent less fatigue. Reported is the mean change of the summed value of all reported scores for the FACT-G or the FACIT-F from baseline to Day 7 ...
OBJECTIVE: To investigate whether fatigue induced by an intermittent motor task in patients with cancer-related fatigue (CRF) is more central or peripheral....
You may expect disease activity and high levels of inflammation to cause your fatigue. Its true they account for much of it, but recent studies have shown that these factors dont tell the whole story. A 2016 study published in Rheumatology found that even when people are in clinical remission, they can still have significant fatigue.. If its not disease activity, what else could be causing your fatigue? In a study published in Arthritis Care & Research in 2016, Patricia Katz, PhD, professor of medicine at University of California San Francisco, and her colleagues found that fatigue may result from a constellation of factors that includes disease activity and pain, but also includes inactivity, depression, obesity and poor sleep.. Pinpointing which factors cause fatigue and which are a result of fatigue is difficult. Katz says the relationships may be cyclic: Fatigue may lead to inactivity and depression; then the inactivity worsens fatigue, depression and poor sleep.. Fatigue can be ...
Chronic fatigue related to cancer is a common syndrome during and following cancer treatment that manifests as a constant lack of energy that is not brought on by exertion, nor relieved by sleep. While cancer-related fatigue is not a well understood problem that can be associated with any single cause, consensus by health authorities is that it is a multifactorial problem involving the bodys reaction to both chemotherapy and radiation therapy; anemia resulting from decreased red blood cells that leaves tissues oxygen starved; and/or a decrease of vital nutrients.. One proposed source of a centuries-old treatment for people suffering from fatigue similar to that experienced by cancer patients is the use of adaptogens. Adaptogens are a class of herbal remedies noted for their potency as stress fighters capable of either bringing an overly stressed body back to its normal healthy state or in coping with stressors such as physical exertion, toxins, lack of sleep and psychological distress.. One of ...
The overall purpose was to explore the experience of living with chronic heart failure among patients in primary healthcare. Comparisons were made between patients with confirmed heart failure (HF, n=49), patients with symptoms indicating HF but with no HF (NHF, n=59), and a reference group (n=40). The mean age was 77 years. Patients in the HF and NHF groups had more general and physical fatigue, more reduced activity, worse physical quality of life and higher degree of depression compared with the reference group. The HF group had also higher degree of physical fatigue and worse physical quality of life than the NHF group. When comparing degrees of depression between the three groups and adjusting for fatigue, the physical dimension of fatigue was of greater importance in explaining group differences. In the HF group general fatigue was more closely related to limitations in role functioning for physical reasons than to reduced physical function per se. Women experienced more fatigue than men. ...
There is no way to know whether you will have fatigue or how bad it will be. But there are things you can do to help fight fatigue. Here are 7 tips to help manage cancer-related fatigue.
The etiology of severe fatigue in T1DM is not well understood. It seems obvious that physiological diabetes-related factors such as haemoglobin A1c (HbA1c) levels or variations in blood glucose levels are associated with fatigue. While fatigue is a classical presenting symptom of hyperglycaemia, in our cross-sectional study no relationship between glucose control (HbA1c levels) and fatigue severity was found [3]. Also, parameters gathered during continuous glucose monitoring such as the blood glucose variability were unrelated to persistent fatigue. Other diabetes-related factors were correlated to fatigue: the number of complications due to diabetes, diabetes-related distress and diabetes specific self-efficacy. Also, there was a univariate relationship between fatigue and somatic comorbidity. In a multiple regression, several cognitive behavioural factors were found to be potential determinants of fatigue: disrupted sleep-wake patterns, low physical activity, catastrophising thoughts about ...
OBJECTIVE: Cancer-related fatigue (CRF) is one of the most common unrelieved symptoms experienced by patients. CRF is underrecognized and undertreated due to a lack of clinically sensitive instruments that integrate easily into clinics. Modern computerized adaptive testing (CAT) can overcome these obstacles by enabling precise assessment of fatigue without requiring the administration of a large number of questions. A working item bank is essential for development of a CAT platform. The present report describes the building of an operational item bank for use in clinical settings with the ultimate goal of improving CRF identification and treatment. STUDY DESIGN AND SETTING: The sample included 301 cancer patients. Psychometric properties of items were examined by using Rasch analysis, an Item Response Theory (IRT) model. RESULTS AND CONCLUSION: The final bank includes 72 items. These 72 unidimensional items explained 57.5% of the variance, based on factor analysis results. Excellent internal ...
What is Adrenal Fatigue: Adrenal Gland Fatigue Symptoms, Test, and Treatments - Born to Be Boomers Could you be experiencing Adrenal Fatigue? See the symptoms.
Results Sjögrens patients had higher scores on all five fatigue dimensions (p,0.001) and lower scores on moderate and vigorous intensity activity (p≤0.001) compared with control participants. In the Sjögrens group, lower physical activity and higher activity avoidance and somatic focus were associated with more severe fatigue on most fatigue dimensions. For general fatigue and physical fatigue, especially the combination of low physical activity and high activity avoidance was associated with more severe fatigue (p,0.05).. ...
Fatigue in patients with cancers of the breast or prostate undergoing radical radiotherapy. To determine the prevalence, severity, and correlates of fatigue among patients with cancers of the Prostate or breast receiving high dose radiotherapy with curative intent, a prospective, questionnaire based study, evaluated a convenience sample of 62 patients who were about to start a course of radiotherapy. Patients were assessed immediately prior to treatment, and again within a week of finishing. Fatigue was assessed using the Fatigue Severity Scale (FSS) and the Bidimensional Fatigue Scale (BFS). Quality of life was assessed using the European Organisation for Research and Treatment of Cancer 30-item Quality of Life Questionnaire (EORTC QLQc30). Psychological distress was assessed using the Hospital Anxiety and Depression Scale (HADS). Personality Traits were assessed using the Eysenck Personality Inventory (EPI). Fatigue severity increased significantly on 3 out of the 5 assessment instruments ...
The objective of this study was to examine whether multiple sclerosis (MS)-related fatigue affects patients cognitive performance. Thirty patients who had substantial fatigue in conjunction with MS and who reported marked diurnal variability in the severity of their fatigue were tested on two occasions: during a period of high fatigue and during a period of relatively low fatigue. The order of these sessions was counterbalanced across patients. During both sessions, patients completed a questionnaire concerning their present state of fatigue and a battery of neuropsychological tests of planning, selective attention, and paired associate learning. Although patients confirmed greater fatigue during the period of high fatigue and felt they had performed more poorly during this period, there were no differences in cognitive performance that could be attributed to fatigue. Instead, all subjects showed improvement from the first to the second session regardless of whether the latter entailed a period ...
Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system is activated, heat shock proteins (HSPs) are produced to protect cells. Some extracellular HSPs appear to recognize cellular targets in the brain, and we hypothesize that fatigue may be generated by specific HSPs signalling through neuronal or glial cells in the central nervous system. From a cohort of patients with primary Sjögrens syndrome, 20 patients with high and 20 patients with low fatigue were selected. Fatigue was evaluated with a fatigue visual analogue scale. Plasma concentrations of HSP32, HSP60, HSP72 and HSP90α were measured and analysed to determine if there were associations with the level of fatigue. Plasma concentrations of HSP90α were significantly higher in patients with high fatigue compared with those with low fatigue, and there was a tendency to ...
The Fatigue Management Guide for Airline Operations supports Fatigue Risk Management Systems (FRMS), presenting the common approach of pilots, regulators and operators to this complex issues
Exercise and/or psychological interventions are more effective strategies than pharmaceutical interventions to reduce cancer-related fatigue.
Stone, P, Ream, E, Richardson, A, Thomas, H, Andrews, P, Campbell, P, Dawson, T, Edwards, J, Goldie, T, Hammick, M et al, Kearney, N, Lean, M, Rapley, D, Smith, AG, Teague, C and Young, A. (2003) Cancer-related fatigue - a difference of opinion? Results of a multicentre survey of healthcare professionals, patients and caregivers ...
The objective of this study is to develop a structured and evidence-based self-management program to cope with cancer-related fatigue and to assess the
Horneber, M; Fischer, I; Dimeo, F; Rüffer, J U; Weis, J Cancer-Related Fatigue: Epidemiology, Pathogenesis, Diagnosis, and Treatment Dtsch Arztebl Int 2012; 109(9): ; DOI: /arztebl
Overall, the patients with newly diagnosed lung cancer had poorer sleep quality, higher depression levels, lower salivary melatonin levels, higher cortisol levels, and flatter melatonin and cortisol slopes than did the controls. The fatigue level and cortisol slope significantly predicted sleep qual …
Fatigue is one of the most common problems for people receiving cancer treatment. Fatigue also can be a symptom of cancer. The fatigue is not the same as fatigue experienced by healthy people. It is described as feeling heavy, weak or worn out, and as having a complete lack of energy. Cancer fatigue can affect a persons quality of life, and can cause depression or other emotional problems.
The specific instruments used for the PROs in this evaluation are well described in published reports. The MOS-Sleep17 is one of several instruments designed to assess sleep and has been shown to have good psychometric properties.14 For measuring fatigue, Wolfe18 reviewed fatigue scales of suitable length or previously used for rheumatic diseases and concluded that the VAS fatigue measure was just as suitable for a simple assessment of fatigue as more extensive scales. However, when it is of interest, a greater understanding of fatigue may be found by evaluating and comparing different domains of fatigue, requiring a multidomain fatigue instrument. Preliminary work has shown that days of limited activity is a simple activity participation measure reflecting real changes in patient clinical status and quality of life, and it is valid, reliable, and sensitive to change.19 Assessment of quality of life is a central PRO. A consensus on the important domains include physical function, ...
OBJECTIVE: To examine patient-reported outcomes (PROs) in patients with different rheumatoid arthritis (RA) disease activity levels and identify residual symptoms. METHODS: Post hoc analyses of overall and Japanese data from two randomized controlled trials including RA patients with previous inadequate responses to methotrexate (NCT01710358) or no/minimal previous disease-modifying antirheumatic drug treatment (NCT01711359) (sponsor: Eli Lilly and Company). Week 24 assessments were disease activity (Simplified Disease Activity Index, Disease Activity Score/Disease Activity Score 28 joints-erythrocyte sedimentation rate) and PROs (pain visual analog scale [VAS], morning joint stiffness [MJS], Health Assessment Questionnaire-Disability Index, Functional Assessment of Chronic Illness Therapy-Fatigue, and Medical Outcomes Study Short Form 36 Health Survey Physical and Mental Component Scores ...
As many as 80 percent of people with lupus experience fatigue. For some people with lupus, fatigue is their main symptom. Fatigue can be debilitating, even to the point of forcing them to stop working.. It is unclear why extreme fatigue occurs in so many people with lupus. Several factors appear to be related to the experience of fatigue. These include disease activity and pain level, medications taken, age, poor mental and/or physical health, and the absence of sufficient social support.. Poor coping strategies, feelings of helplessness, depression or anxiety, smoking, and lack of exercise can also be related to lupus fatigue. Before a physician can conclude that fatigue is related to these factors, he or she will rule out any treatable causes of fatigue such as anemia, kidney failure, or hypothyroidism.. Physicians experienced with lupus recognize the harmful and even destructive effects that extreme fatigue can have, and research is underway to learn more about how to treat the ...
Objective. Sleep disturbance and chronic fatigue are common in rheumatoid arthritis (RA) and contribute to disability, symptomatology, and healthcare use. It has long been recognized in other populations that exercise can improve sleep and diminish fatigue. The effect of exercise on sleep quality and fatigue in RA has not been evaluated. Methods. Ours is a randomized controlled study in RA to determine the effect of an exercise program on sleep quality and fatigue. These were measured using the Pittsburgh Sleep Quality Index and the Fatigue Severity Scale. Patients were randomized to either a 12-week, home-based exercise intervention or usual care. The exercise program consisted of specific exercises to target individual deficiencies identified using the Health Assessment Questionnaire (HAQ) with cardiovascular work as per the guidelines. The intervention group was evaluated on a 3-week basis. Full evaluation was carried out at baseline and at 12 weeks. Results. Forty patients were randomized to ...
Context: High quality fatigue rating scales are needed to advance understanding of fatigue nd determine the efficacy of interventions. Several fatigue scales are used in Parkinsons isease, but few have been tested using modern psychometric methodology (Rasch analysis).. Objectives: To examine the measuring properties of the generic Functional Assessment of hronic Illness Therapy - Fatigue (FACIT-F) scale and the condition-specific 16-item arkinson Fatigue Scale (PFS-16) using Rasch analysis.. Methods: Postal survey data (n=150; 47% women; mean age, 70) were Rasch analyzed. FS-16 scores were tested according both to the original polytomous and the suggested lternative dichotomized scoring methods.. Results: The PFS-16 showed overall Rasch model fit whereas the FACIT-F showed signs of isfit, which probably was due to a sleepiness-related item and mixing of ositively/negatively worded items. There was no differential tem functioning by disease uration but by fatigue status (greater likelihood of ...
TY - JOUR. T1 - Chasing the silver bullet: measuring driver fatigue using simple and complex tasks. AU - Baulk, Stuart. AU - Biggs, Sarah. AU - Reid, Kathryn. AU - van den Heuvel, Cameron. AU - Dawson, Drew. PY - 2008. Y1 - 2008. N2 - Driver fatigue remains a significant cause of motor-vehicle accidents worldwide. New technologies are increasingly utilised to improve road safety, but there are no effective on-road measures for fatigue. While simulated driving tasks are sensitive, and simple performance tasks have been used in industrial fatigue management systems (FMS) to quantify risk, little is known about the relationship between such measures. Establishing a simple, on-road measure of fatigue, as a fitness-to-drive tool, is an important issue for road safety and accident prevention, particularly as many fatigue related accidents are preventable. This study aimed to measure fatigue-related performance decrements using a simple task (reaction time - RT) and a complex task (driving simulation), ...
This unit involves the skills and knowledge required to manage organisational fatigue management policy and procedures in accordance with relevant legislation and regulations.
Fatigue detection software is intended to reduce fatigue related fatalities and incidents. Several companies are working on a technology for use in industries such as mining, road- and rail haulage and aviation. The technology may soon find wider applications in industries such as health care and education. In an operational environment scenario where operating systems are dependent on human performance, fatigue can be defined as an inclination to degrade performance. Thus, fatigue is an indicator of baseline risk for the occurrence of errors and accidents. Globally mining operations are at risk of fatigued workers. Sleepiness and fatigue increase human error and contribute to accidents which can be fatal. Factors compounding fatigue levels in mine workers include; disruptions in circadian rhythms due to shift work, exposure to noise, vibration and chemicals, monotonous and repetitive nature of tasks and night shift driving. Studies recognise a connotation between lifestyle and fatigue. Mine ...
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Background. Fatigue is a frequently reported symptom in women following early breast cancer treatment and may be increased with adjuvant breast radiotherapy (RT). Within the START Quality of Life (QoL) sub study the effect of a range of clinical and psychological factors and symptoms on fatigue is investigated in women following RT for early stage breast cancer.. Method. A subgroup of women were recruited to the QoL study and completed the EORTC QLQ C-30, BR23 and HADS at baseline (after surgery +/- chemotherapy (CT) but before RT) and at 6, 12, 24 and 60 months. Fatigue was measured as a symptom subscale comprised of 3 individual items. The effect of age, time from surgery, type of surgery, CT, endocrine therapy, RT schedule and change over time were tested using a GEE model. Correlations between fatigue and anxiety, depression, insomnia and physical functioning were examined.. Results. 2180 (99%) women completed baseline QoL. Fatigue levels were highest pre RT (median 33.33) and decreased ...
PURPOSE: Fatigue is a symptom in patients with chronic gastrointestinal (GI) and liver diseases. Different instruments have been developed to assess the severity of fatigue and the 40-item Fatigue Impact Scale (FIS) is among the most widely used. Shorter versions of FIS include the 21-item Modified Fatigue Impact Scale (MFIS), and an eight-item version for everyday use. The study aimed to assess construct validity, reliability, and sufficiency of the raw score of the original FIS with 40 items, and examine the sufficiency of the 21 items from the Modified scale and the eight items of the Daily Fatigue Impact Scale (D-FIS), all of which are embedded in the 40-item scale ...
Introduction: Fatigue is the most troublesome untreated symptom during radical breast radiotherapy. This situation persists due to an uncertain aetiology and an inability to identify patients at high risk of experiencing significant fatigue during subsequent radiotherapy. Aetiological investigations of the current study concentrated on discriminating the radiotherapy-specific effects on fatigue, in a context encompassing multiple psychological and physiological covariates. Prognostic aspects sought to characterise a high-risk patient. Methods: The study cohort comprised 100 women, diagnosed with Stage 0 to IIA breast cancer, and prescribed standard whole breast irradiation to 40Gy in 15 fractions over three weeks. The use of systemic therapies was an exclusion criterion. A cytokine-induced sickness behaviour model framed the study investigations, and provided a theoretical link between localised radiotherapy and systemic fatigue. The outcome fatigue was assessed before, during and four weeks ...
The Fatigue Severity Score (FSS), the Fatigue Impact Scale (FIS), and the ModifiedFatigue Impact Scale (MFIS) are the most commonly used scales for fatigue assess-ment in MS patients.The FSS is composed of 9 items that assess perceivedSubjects are asked to assign a number from 1 (strongly disagree) to 7(strongly agree) stating their agreement with each statement.Responses aresummed and averaged, with a score of 4 or more indicating significant The FIS has been identified by the Multiple Sclerosis Council for Clinical Practice Guidelines as the most appropriate for assessing the impact of MS-related fatigueon quality of life.The FIS is a retrospective tool designed to evaluate fatigue duringthe past month. The FIS has separate subscales for physical, psychosocial, andcognitive functions, which span more than 40 statements.Subjects are asked toscore the effect of fatigue on those 4 dimensions using a 5-point scale from 0 (noproblem) to 4 (extreme problem). Since the FIS takes approximately 10 to ...
Our results suggest that ASA may improve some self-report measures of fatigue impact and severity. Baseline fatigue levels and outcomes were not affected by clinical variables, increasing the likelihood that we measured a common MS fatigue construct. We detected a treatment response despite confounders such as prior fatigue therapy use (33%) and current use of antidepressants or immunomodulatory drugs. We did not detect fatigue reduction on all outcome measures. Potential explanations include that individual scales measure diverse aspects of the fatigue construct, psychometric properties of scales differ, and characteristics of our patient sample may differ from other studies.5. Known pharmacological mechanisms of ASA, especially regarding fever, may be relevant to our results.6,7 ASA mediates the febrile response at the hypothalamus by irreversibly inhibiting cyclooxygenase and blocking prostaglandin E2 production. In MS, these effects could modulate hypothalamic output, thereby affecting ...
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PURPOSE: Fatigue is a distressing symptom occurring in more than 60% of patients with cancer. The CNS stimulants modafinil and methylphenidate are recommended for the treatment of cancer-related fatigue, despite a limited evidence base. We aimed to evaluate the efficacy and tolerability of modafinil in the management of fatigue in patients with non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: Adults with advanced NSCLC and performance status of 0 to 2, who were not treated with chemotherapy or radiotherapy within the last 4 weeks, were randomly assigned to daily modafinil (100 mg on days 1 to 14; 200 mg on days 15 to 28) or matched placebo. The primary outcome was change in Functional Assessment of Chronic Illness Therapy (FACIT) -Fatigue score from baseline to 28 days, adjusted for baseline fatigue and performance status. Secondary outcomes included safety and patient-reported measures of depression, daytime sleepiness, and quality of life. RESULTS: A total of 208 patients were randomly
Overcoming Barriers. Fatigue. Fatigue is common in MS, exercise and fatigue management education strategies will actually help your fatigue level in the long term(8).. Heat Sensitivity and MS. Physical and sensory symptoms may temporarily increase with small increases in environmental or body temperature. People with MS should be encouraged to keep cool and well hydrated during exercise sessions, for example using cool clothing and try to exercise inside or in the shade.. Research is continuing to address what exercise and strategies are best for fatigue and heat sensitivity; for now it is recommended to follow the Physical activity guidelines, remember to build up to these guidelines slowly. Stretching exercises are important too, and continuing these when fatigue levels, or temperatures, are high is still important.. Finding support. Support to help you exercise is not to be underestimated. Research indicates that learning about exercise, working with other to overcome your barriers and ...
Background: Fatigue is widespread in the population and a common complaint in primary care. Little is known about prevalence of fatigue in the population and its predictors. We aimed to describe the pattern of fatigue in the general population and to explore the associations with age, sex, socioeconomic status, self-reported physical activity, sitting time and self-rated health.. Methods: One thousand, five hundred and fifty-seven out of 2500 invited subjects in the Northern Sweden MONICA Study 2014, aged 25-74 years, filled out the Multidimensional Fatigue Inventory (MFI-20), consisting of four subscales: General fatigue (GF), Physical fatigue (PF), Reduced activity (RA) and Mental fatigue (MF). Questions regarding age, sex, socioeconomic status, physical activity, sitting time and self-rated health were also included.. Results: Higher age correlated significantly with lower fatigue scores for the GF and MF subscales. Women had higher fatigue scores than men on all subscales (p , 0.05). Among ...
Validated or standardized self-report questionnaires used in research studies and clinical evaluation of chronic fatigue syndrome (CFS) generally focus on the assessment of fatigue. There are relatively few published questionnaires that evaluate case defining and other accompanying symptoms in CFS. This paper introduces the self-report CDC CFS Symptom Inventory and analyzes its psychometric properties. One hundred sixty-four subjects (with CFS, other fatiguing illnesses and non fatigued controls) identified from the general population of Wichita, Kansas were enrolled. Evaluation included a physical examination, a standardized psychiatric interview, three previously validated self-report questionnaires measuring fatigue and illness impact (Medical Outcomes Survey Short-Form-36 [MOS SF-36], Multidimensional Fatigue Inventory [MFI], Chalder Fatigue Scale), and the CDC CFS Symptom Inventory. Based on theoretical assumptions and statistical analyses, we developed several different Symptom Inventory scores
Resveratrol (RES) is a well-known phytocompound and food component which has antioxidative and multifunctional bioactivities. However, there is limited evidence for the effects of RES on physical fatigue and exercise performance. The purpose of this study was to evaluate the potential beneficial effects of trans-RES on fatigue and ergogenic functions following physiological challenge. Male ICR mice from four groups (n = 8 per group) were orally administered RES for 21 days at 0, 25, 50, and 125 mg/kg/day, which were respectively designated the vehicle, RES-25, RES-50, and RES-125 groups. The anti-fatigue activity and exercise performance were evaluated using forelimb grip strength, exhaustive swimming time, and levels of serum lactate, ammonia, glucose, and creatine kinase (CK) after a 15-min swimming exercise. The exhaustive swimming time of the RES-25 group (24.72 ± 7.35 min) was significantly (p = 0.0179) longer than that of vehicle group (10.83 ± 1.15 min). A trend analysis revealed that RES
To study fatigue in young adults with juvenile idiopathic arthritis (JIA) 18 years after disease onset, and to compare with controls. Consecutive children with onset of JIA between 1997 and 2000, from geographically defined areas of Norway, Sweden, Denmark and Finland were followed for 18 years in a close to population-based prospective cohort study. Clinical features, demographic and patient-reported data were collected. Inclusion criteria in the present study were a baseline visit 6 months after disease onset, followed by an 18-year follow-up with available self-reported fatigue score (Fatigue Severity Scale (FSS), 1-7). Severe fatigue was defined as FSS ≥4. For comparison, Norwegian age and sex matched controls were used. Among 377 young adults with JIA, 26% reported severe fatigue, compared to 12% among controls. We found higher burden of fatigue among participants with sleep problems, pain, poor health, reduced participation in school/work, physical disability, active disease, or use of disease
|jats:p|In this study we set out to define the characteristics of autonomic subgroups of patients with Chronic Fatigue Syndrome (CFS). The study included 131 patients with CFS (Fukuda criteria). Participants completed the following screening symptom assessment tools: Chalder Fatigue Scale, Fatigue Impact Scale, Fatigue Severity Scale, Epworth Sleepiness Scales, the self-reported Composite Autonomic Symptom Scale. Autonomic parameters were measured at rest with a Task Force Monitor (CNS Systems) and arterial stiffness using an Arteriograph (TensioMed Kft.). Principal axis factor analysis yielded four factors: fatigue, subjective and objective autonomic dysfunction and arterial stiffness. Using cluster analyses, these factors were grouped in four autonomic profiles: 34% of patients had sympathetic symptoms with dysautonomia, 5% sympathetic alone, 21% parasympathetic and 40% had issues with sympathovagal balance. Those with a sympathetic-dysautonomia phenotype were associated with more severe disease,
Severe fatigue is a major health problem in fibromyalgia (FM). Obesity is common in FM, but the influence of adipokines and growth factors is not clear. The aim was to examine effects of exercise on fatigue, in lean, overweight and obese FM patients. In a longitudinal study, 48 FM patients (median 52 years) exercised for 15 weeks. Nine patients were lean (body mass index, BMI 18.5 to 24.9), 26 overweight (BMI 25 to 29.9) and 13 obese. Fatigue was rated on a 0 to 100 mm scale (fibromyalgia impact questionnaire [FIQ] fatigue) and multidimensional fatigue inventory (MFI-20) general fatigue (MFIGF). Higher levels in FIQ fatigue and MFIGF indicate greater degree of fatigue. Free and total IGF-1, neuropeptides, adipokines were determined in serum and cerebrospinal fluid (CSF). Baseline FIQ fatigue correlated negatively with serum leptin (r = -0.345; P = 0.016) and nerve growth factor (NGF; r = -0.412; P = 0.037). In lean patients, baseline MFIGF associated negatively with serum resistin (r = -0.694; P = 0.038
The aim of this study was to explore perceived fatigue, experienced functional limitations due to fatigue and clinical correlates in patients with Myotonic Dystrophy type 1 (DM1). In total, 32 consecutive patients with DM1 (14 women and 18 men) and 30 sex, age and education matched healthy control subjects participated. Perceived fatigue was rated on the Fatigue Impact Scale (FIS). Patients also completed a set of assessments aimed to characterize CTG-repeat size, muscle impairment, depression and cognitive functions. Non-parametric analysis were performed as appropriate, including Mann-Whitney U-test and Spearman correlation test. DM1 patients had higher FIS total score than healthy controls, suggesting higher fatigue levels. More specifically, DM1 patients scored higher on the FIS physical and psychosocial subscales than controls but not on the FIS cognitive scale. Scores on fatigue correlated significantly with muscle impairment and depression. Perceived fatigue is significantly more common in
Emergency response providers constitute an occupational group that is particularly vulnerable to the effects of sleepiness and fatigue. Considering the work they do, such a vulnerability poses significant risks to the health and safety of the responders themselves and of the general public. The development and implementation of fatigue management programs, plans, and policies for emergency response providers is therefore essential to protecting the health and safety of this critical segment of the workforce, as well as the people it serves.. In the short term, sleep loss and excessive periods of wakefulness are associated with sleepiness, which can cause both job performance problems (e.g., errors, failure of empathy) and work-related injuries (e.g., driving accidents), and possibly harm to the public if the emergency response provider has a failure in judgment or makes a technical error. In the longer term, working without adequate recovery between shifts can lead to fatigue, which can have ...
Cancer-related fatigue (CRF) is a common and distressing symptom of cancer and/or cancer treatment that persists for years after treatment completion in approximately one third of cancer survivors. Exercise is beneficial for the management of CRF, and general exercise guidelines for cancer survivors are available. There are multiple potential pathways by which exercise improves CRF, and cancer survivors with CRF are diverse with respect to cancer type, treatments and experienced side effects. While the general exercise guidelines are likely sufficient for most cancer survivors, tailoring of exercise interventions may be more effective in those with persistent fatigue. The primary aim of this research is to investigate the effect of a traditional vs. tailored exercise intervention on CRF severity in cancer survivors with persistent CRF. Cancer survivors (≥ 3 months and ≤ 5 years since primary treatment) who score ≤ 34 on the Functional Assessment of Chronic Illness Therapy Fatigue Scale (FACIT-F)
Publication Year and Month: 2013 12. Abstract: We evaluate the reliability, validity, and responsiveness of the Fatigue Severity Scale (FSS) and the Fatigue Impact Scale (FIS) and to determine whether these scales are potentially applicable for measuring fatigue in postpolio patients (PPS). After the Turkish adaptation of FSS and FIS using a forward-backward procedure, the scales were administered to 48 PPS patients without additional health problems that may induce fatigue. Reliability studies were carried out by determination of intraclass correlation coefficient and internal consistency by the Cronbach-α coefficient. Validity was tested by within-scale analyses and analyses against the external criteria including convergent validity and discriminant validity. Correlations with the Notthingham Health Profile (NHP), fatigue, pain and cramp severity (visual analog scale), and manual muscle testing were performed. Sensitivity to changes was determined by standardized response mean values. All ...
The prevalence of fatigue is high in patients with systemic lupus erythematosus (SLE). In this study, we used latent class analysis to reveal patterns of fatigue, anxiety, depression and organ involvement in a large international cohort of SLE patients.We used the Lupus BioBank of the upper Rhein to analyse patterns of fatigue using latent class analysis (LCA). After determining the optimal number of latent classes, patients were assigned according to model generated probabilities, and characteristics of classes were compared.A total of 502 patients were included. Significant fatigue, anxiety and depression were reported by 341 (67.9%), 159 (31.7%) and 52 (10.4%) patients, respectively. LCA revealed a first cluster (67.5% of patients) with low disease activity [median (25th-75th percentile interquartile range) Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA)-SLEDAI: 2 (0-4)], significant fatigue (55.5%, P ...
A recent University of Iowa study reveals a biological link between pain and fatigue and may help explain why more women than men are diagnosed with chronic pain and fatigue conditions like fibromyalgia and chronic fatigue syndrome.. Working with mice, the researchers, led by Kathleen Sluka, Ph.D., professor in the Graduate Program in Physical Therapy and Rehabilitation Science in the UI Roy J. and Lucille A. Carver College of Medicine, found that a protein involved in muscle pain works in conjunction with the male hormone testosterone to protect against muscle fatigue.. Chronic pain and fatigue often occur together -- as many as three in four people with chronic, widespread musculoskeletal pain report having fatigue; and as many as 94 percent of people with chronic fatigue syndromes report muscle pain. Women make up the majority of patients with these conditions.. To probe the link between pain and fatigue, and the influence of sex, the UI team compared exercise-induced muscle fatigue in male ...
A daily cup of flavonoid-rich cocoa may help ease fatigue in people with relapsing-remitting multiple sclerosis (RRMS), according to the results of a small clinical trial.. The study A randomised double-blind placebo-controlled feasibility trial of flavonoid-rich cocoa for fatigue in people with relapsing and remitting multiple sclerosis was published in the Journal of Neurology, Neurosurgery & Psychiatry.. Fatigue is experienced by 90% of people with MS and, despite many approaches for fatigue management, exercise shows signs of being the most effective. However, even exercise has its limitations, and beneficial strategies are needed.. Dark chocolate containing 70 to 85% cocoa solids has shown success in improving fatigue in people with chronic fatigue syndrome. A small trial showed that consumption of flavonoid rich dark cocoa for a short term increased sleep quality and reduced fatigue in people with MS.. Flavonoids are a type of antioxidant found in several plant-based foods, such as dark ...
Study finds the Multidimensional Fatigue Inventory to be more valuable in assessing fatigue in fibromyalgia patients than the Fibromyalgia Impact Qu
Furthermore, age, gender, indication for transplantation, and time since transplantation were evaluated.. The team also assessed immunosuppressive medication, self-experienced disability, and health-related quality of life as potential associated factors.. The researchers found that 66% of all patients were fatigued, and 44% of all patients were severely fatigued.. Patients experienced physical fatigue with reduced activity rather than mental fatigue and reduced motivation.. Age, gender, self-experienced disabilities, and health related quality of life were factors that correlated with severity of fatigue.. Dr van den Berg-Emons team concluded, This study indicates that fatigue is a major problem in patients after liver transplantation, and no indications were found that complaints of fatigue improve over time. Liver transplant recipients experience physical fatigue and reduced activity rather than mental fatigue and reduced motivation. These findings have implications for the development of ...
Muscle fatigue reduces muscle strength and balance control in young people. It is not clear whether fatigue resistance seen in older persons leads to different effects. In order to understand whether muscle fatigue may increase fall risk in older persons, a systematic literature review aimed to summarize knowledge on the effects of lower extremity and trunk muscle fatigue on balance and functional tasks in older people was performed. Studies were identified with searches of the PUBMED and SCOPUS data bases. Papers describing effects of lower extremity or trunk muscle fatigue protocols on balance or functional tasks in older people were included. Studies were compared with regards to study population characteristics, fatigue protocol, and balance and functional task outcomes. Seven out of 266 studies met the inclusion criteria. Primary findings were: fatigue via resistance exercises to lower limb and trunk muscles induces postural instability during quiet standing; induced hip, knee and ankle muscle
Fatigue damage behaviors of four metal materials in the very high cycle fatigue (VHCF) regime have been studied using ultrasonic fatigue test and microstructure analysis. The results show that the fatigue crack initiation in VHCF regime could occur at subsurface non-defect fatigue crack origin (SNDFCO), where the accumulated cyclic strains or damage in the specimens were highly localized, especially in the materials with some softer phase, where the local maximum strain can be eight times higher than the average strain value in the specimen. This high strain localization can cause a local plasticity exhaustion that leads to a stress concentration and consequently fatigue crack initiation, and finally the formation of SNDFCO. For pure single phase austenitic material, strain localization can also occur due to dislocation accumulation at or near grain boundaries, which can become fatigue crack initiation origin in the VHCF regime. The results in this study show that fatigue damage and crack ...
Study Purpose: The effects of fatigue on human behavior, performance, and physiology are well understood and widely known. Excess fatigue arising from sleep loss, circadian disruption, and other factors tends to decrease alertness, impair performance, and worsen mood. As such, it is reasonable to expect that the performance, health, and safety of patrol officers, as well as police-community relations, are adversely affected by the fatigue an officer may experience. This study was undertaken to assess the connections between administratively controllable sources of fatigue among police patrol officers and problems such as diminished performance, accidents, and illness. The study sought to answer: (1) What is the prevalence of officer fatigue, and what are officers attitudes toward it? (2) What are the causes or correlates of officer fatigue? (3) How does fatigue affect officer safety, health, and job performance? and (4) Can officer fatigue be measured objectively? Study Design: Four police ...
The research investigated relationships between subjective fatigue, performance, and four physiological parameters: sinus arrhythmia, pupil behavior, blink rate, and tension of the neck muscles. Fatigue was induced by a doppler recognition task and rigid body posture. Performance was measured as the proportion of correct doppler identifications. There was no detection of a performance change during the two and one half-hour experimental sessions. Sinus arrhythmia and eyelid blink rate were also found to remain unchanged. An alteration was found in the measures of neck muscle tension levels, subjective fatigue, and the average pupil diameter. Subjective ratings of fatigue were found to be highly correlated with time-on-task and the electromyographic response of certain neck muscles. Polynomial regression indicated a significant linear relationship between the subjective ratings and the tension measured. (Author)*FATIGUE
muscle fatigue - MedHelps muscle fatigue Center for Information, Symptoms, Resources, Treatments and Tools for muscle fatigue. Find muscle fatigue information, treatments for muscle fatigue and muscle fatigue symptoms.
THURSDAY, Oct. 30, 2014 (HealthDay News) -- There are clear differences in the brains of people with chronic fatigue syndrome and the brains of healthy people, new research indicates. Scientists at Stanford University School of Medicine said their findings could help doctors diagnose this baffling condition and shed light on how it develops. People with chronic fatigue syndrome are often misdiagnosed or labeled as hypochondriacs. Using three types of brain scanning technologies, we found that [chronic fatigue syndrome] patients brains diverge from those of healthy subjects in at least three distinct ways, said the studys lead author, Dr. Michael Zeineh, assistant professor of radiology, in a Stanford news release.. Chronic fatigue syndrome affects up to 4 million people in the United States alone, says the U.S. Centers for Disease Control and Prevention. The condition, which causes debilitating and constant fatigue that persists for six months or more, is difficult to diagnose. Other ...
TY - GEN. T1 - Fatigue life properties and anomalous macroscopic fatigue fracture surfaces of low carbon steel JIS-SM490B in high-pressure hydrogen gas environment. AU - Ogawa, Yuhei. AU - Matsunaga, Hisao. AU - Yoshikawa, Michio. AU - Yamabe, Junichiro. AU - Matsuoka, Saburo. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Tension-compression fatigue tests using smooth specimens of low carbon steel JIS-SM490B were carried out in air and hydrogen gas environment under the pressure of 0.7 and 115 MPa at room temperature. In 0.7 MPa hydrogen gas, fatigue life curve was nearly equivalent to that in air. On the other hand, in 115 MPa hydrogen gas, fatigue life was significantly degraded in the relatively short fatigue life regime (e.g. Nf , 105). To clarify the effect of hydrogen environment on fracture process, fracture surfaces of these specimens were observed. In general, fatigue fracture process of steels with low or moderate strength is macroscopically divided into 3 stages. In the first stage (stage I), ...
Subjects in the experimental group received acupressure for 12 minutes per day, followed by a three-minute massage of the legs, three days a week, for four weeks. The acupressure points Zusanli, Sanyinjiao, Taixi and Yungchuan were deemed appropriate for easing fatigue and depression.. These points were pressed and rubbed using the pads of the fingers with a force of about three-to-five kilograms for five seconds, with a one-second release at the end. Each point was stimulated for three minutes. After 12 minutes of acupressure, subjects legs were massaged for three minutes.. Researchers used the revised Piper Fatigue Scale to measure fatigue, and the Chinese version of Becks Depression Inventory was used to measure depression, at the beginning and end of the four-week study. The results of the study revealed a significant decrease in perceived fatigue from the start to the finish of the study for subjects in the experimental group, whereas the control group showed no significant difference in ...
BACKGROUND: Checkpoint inhibitors have changed overall survival for patients with advanced melanoma. However, there is a lack of data on health-related quality of life (HRQoL) of long-term advanced melanoma survivors, years after treatment. Therefore, we evaluated HRQoL in long-term advanced melanoma survivors and compared the study outcomes with matched controls without cancer.. MATERIAL AND METHODS: Ipilimumab-treated advanced melanoma survivors without evidence of disease and without subsequent systemic therapy for a minimum of two years following last administration of ipilimumab were eligible for this study. The European Organization for Research and Treatment of Cancer quality of life questionnaire Core 30 (EORTC QLQ-C30), the Multidimensional Fatigue Inventory (MFI), the Hospital Anxiety and Depression Scale (HADS), and the Functional Assessment of Cancer Therapy-Melanoma questionnaire (FACT-M) were administered. Controls were individually matched for age, gender, and educational status. ...
Then there is the mental fatigue, which resembles the brain fog many lupus patients experience. I find mental fatigue very exasperating. I am a student of biology at university and compared to the focused, productive student I used to be at school ten years ago, I barely recognise myself. My brain feels like it is wading through mud and I feel like I am being constantly followed by a foggy cloud, which sucks the thoughts and life out of me. I find it very hard to concentrate and focus. I often end up reading the same thing over and over again and nothing will sink through. I seem to have no short-term memory and Im always forgetting what I am meant to be saying half-way through my sentences. I curse myself for this, though I know it is not my fault, because the fog makes me feel dumb and stupid. To those who dont understand, I appear slow, or anxious or bird-brained. Just like physical fatigue, this sort of fatigue is very difficult to explain to those who dont walk in our shoes. ...
The aim of this study was to identify subsets of patients with fibromyalgia with similar symptom profiles using the Outcome Measures in Rheumatology (OMERACT) core symptom domains. Female patients with a diagnosis of fibromyalgia and currently meeting fibromyalgia research survey criteria completed the Brief Pain Inventory, the 30-item Profile of Mood States, the Medical Outcomes Sleep Scale, the Multidimensional Fatigue Inventory, the Multiple Ability Self-Report Questionnaire, the Fibromyalgia Impact Questionnaire-Revised (FIQ-R) and the Short Form-36 between 1 June 2011 and 31 October 2011. Hierarchical agglomerative clustering was used to identify subgroups of patients with similar symptom profiles. To validate the results from this sample, hierarchical agglomerative clustering was repeated in an external sample of female patients with fibromyalgia with similar inclusion criteria. A total of 581 females with a mean age of 55.1 (range, 20.1 to 90.2) years were included. A four-cluster solution best
Severe fatigue is a common complaint among patients. Often, the fatigue is transient or can be attributed to a definable organic illness. Some patients present with persistent and disabling fatigue, but show no abnormalities on physical examination or screening laboratory tests. In these cases, the diagnosis of chronic fatigue syndrome (CFS) should be considered. CFS is characterized by debilitating fatigue with associated myalgias, tender lymph nodes, arthralgias, chills, feverish feelings, and postexertional malaise. Diagnosis of CFS is primarily by exclusion with no definitive laboratory test or physical findings. Medical research continues to examine the many possible etiologic agents for CFS (infectious, immunologic, neurologic, and psychiatric), but the answer remains elusive. It is known that CFS is a heterogeneous disorder possibly involving an interaction of biologic systems. Similarities with fibromyalgia exist and concomitant illnesses include irritable bowel syndrome, depression, and
Chronic fatigue syndrome (CFS) treatments alleviate chronic fatigue symptoms whether the causes of fatigue are viral (including the Epstein Barr virus) or due to another immune dysfunction syndrome. T...
Despite strong indications that fatigue is the most common and debilitating symptom after traumatic brain injury, little is known about its frequency, natural history, or relation to other factors. The current protocol outlines a strategy for a systematic review that will identify, assess, and critically appraise studies that assessed predictors for fatigue and the consequences of fatigue on at least two separate time points following traumatic brain injury. MEDLINE, EMBASE, the Cochrane Database of Systematic Reviews, CINAHL, and PsycINFO will be systematically searched for relevant peer-reviewed studies. Reference lists of eligible papers will also be searched. All English language studies with a longitudinal design that focus on fatigue in adults with primary-impact traumatic brain injury will be included. Studies on fatigue following brain injury due to secondary pathological processes (intracranial complications, edema, ischemia/infarction, and systemic intracranial conditions) will be excluded.
Testing of large prototype lead zirconate titanate (PZT) stacks presents substantial technical challenges to electronic testing systems, so an alternative approach that uses subunits extracted from prototypes has been pursued. Extracted 10-layer and 20-layer plate specimens were subjected to an electric cycle test under an electric field of 3.0/0.0 kV/mm, 100 Hz to 10{sup 8} cycles. The effects of measurement field level and stack size (number of PZT layers) on the fatigue responses of piezoelectric and dielectric coefficients were observed. On-line monitoring permitted examination of the fatigue response of the PZT stacks. The fatigue rate (based on on-line monitoring) and the fatigue index (based on the conductance spectrum from impedance measurement or small signal measurement) were developed to quantify the fatigue status of the PZT stacks. The controlling fatigue mechanism was analyzed against the fatigue observations. The data presented can serve as input to design optimization of PZT ...
For a complete list, please see Holmes, et al.1 When you have ruled out all these conditions, there is a good chance you have a chronic fatigue patient on your hands. Many times the chiropractor is not the first professional a chronic fatigue (CF) patient has seen, often coming to us as a last resort. Also, many CF patients will enter our offices not for treatment of CF, but for relief of the musculoskeletal complaints that often accompany it. It is no secret that the allopathic practitioners who believe in CF have a difficult problem treating this condition. There are also many doctors who incorrectly call chronic fatigue patients depressed. Depression certainly can cause fatigue, and many fatigued patients are depressed, but we must find out which came first. Obviously, if every doctor in town tells you that you dont have a problem, it would be hard not to get depressed. Chronic Fatigue Syndrome (CFS) seems to be a postviral dysfunction of the bodys energy production system. It can affect ...
Hello Chronic Fatigue Syndrome or Chronic Fatigue Immune Dysfunction (CFIDS) became apparent in the mid 1980s as an epidemic characterized by debilitating fatigue and a host of other symptoms such...
New York, June 28 (IANS) Contrary to common perception, chronic fatigue syndrome may not be psychological in origin as researchers have now identified biological markers of the disease in gut bacteria and inflammatory microbial agents in the blood. The findings suggest that changing diets, using prebiotics such as dietary fibers or probiotics could treat chronic fatigue syndrome, a condition where normal exertion leads to debilitating fatigue that is not alleviated by rest.. Physicians have been mystified by the disease as there are no known triggers, and diagnosis often requires lengthy tests administered by an expert.. Now, for the first time, Cornell University researchers described how they correctly diagnosed myalgic encephalomyeletis/chronic fatigue syndrome (ME/CFS) in 83 per cent of patients through stool samples and blood work, offering a noninvasive diagnosis and a step toward understanding the cause of the disease.. Our work demonstrates that the gut bacterial microbiome in chronic ...
Diagnosis and treatment of OC, mostly comprising debulking surgery and subsequent chemotherapy, entail severe symptom burden and a significant loss of patients quality of life.. Correspondingly, our study results indicate impairments for a wide range of somatic and psychological symptoms at the beginning of chemotherapy. Thus, at baseline, levels of anxiety and the prevalence of depressive symptoms were increased as reflected by self- as well as proxy-ratings. Similarly, fatigue (in terms of general fatigue, physical fatigue and reduced activity) was found to be high. Patients, however, recovered significantly over time up until aftercare. A strong improvement was not only found for anxiety and regarding the prevalence of depressive symptoms but also for almost all aspects of functioning covered by the QLQ-C30 as well as for fatigue (less pronounced for mental fatigue and reduced motivation). Both HADS as well as MFI-20 scores returned toward general population levels [30, 31].. From a clinical ...
Although physical and emotional fatigue is the most common side effect of cancer treatment, it remains underreported, underdiagnosed, and undertreated. Yet the exhaustion patients experience can significantly interfere with their daily functioning, and fatigue can persist for months or even years after treatment ends.. Of the non-pharmacologic interventions for cancer-related fatigue, researchers have found exercise to have the strongest potential to produce a therapeutic benefit. Exercise improves a wide range of biopsychosocial outcomes in patients with cancer. Studies have demonstrated that patients who exercise are less tired, less depressed, and sleep better. Of course, this can be counterintuitive for patients, who often reduce or stop exercising when undergoing fatigue-inducing treatments such as radiation. To counteract this impulse, oncology social workers at Mount Sinai Downtown Cancer Centers in New York City developed a quality improvement initiative to teach patients about the ...
In other words, when we have to cope with high stress situations our adrenal glands manufacture more adrenalin. If the stress is prolonged enough, the glands become exhausted, resulting in not only physical fatigue, but also depression and susceptibility to infection. Pregnenolone was tested with people with stressful job situations, such as airline pilots, and confirmed that psychomotor performance improved. It also enhanced the performance of various labour orientated jobs, including lathe workers and leather cutters. Performance was assessed on the basis of overall productivity, quality of work, frequency of mistake and mental and physical fatigue.. Rheumatoid arthritis ...
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We all know what it is to be exhausted: fatigue seems to be a normal part of human experience when we are overactive, have physical or emotional problems, face stress, or suffer from insomnia. Some of us, in fact, suffer from chronic fatigue syndrome, an illness characterized by pervasive fatigue that produces significant disability and lasts more than six months. In this important book, an eminent specialist in fatigue disorders-a physician who is sensitive and empathic to patients complaints-discusses all kinds of fatigue problems, explaining what fatigue is, what causes it, how to combat it, and what patients should know when consulting a doctor about symptoms.The book offers valuable advice on:• how to improve your sleep; • ways to find understanding and sympa thetic doctors; • self-help techniques to manage stress (the role of exercise, relaxation, and coaches); • the best medicines and ancillary techniques used by expert physicians to treat severe
chronic; fatigue; syndrome; myalgic; encephalopathy; ; Chronic Fatigue Syndrome is an illness which causes severe, disabling fatigue (tiredness) after physical and mental activity, far beyond what is usually felt. Resting and sleeping will help for a while, but even when people get enough sleep, they still feel tired and get exhausted quickly. Sometimes the pattern of health problems that are called chronic fatigue syndrome are called Myalgic encephalomyelitis (ME).. To find out more. Raising Children Network ...
ABSTRACT: Objective - Poor sleep quality has been linked to inflammatory processes and worse disease outcomes in the context of many chronic illnesses, but less is known in conditions such as chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). This study examines the relationships between sleep quality, pro-inflammatory cytokines, and CFS/ME symptoms. Methods - Sixty women diagnosed with CFS/ME were assessed using the Pittsburgh Sleep Quality Index (PSQI), Fatigue Symptom Inventory (FSI) and Center for Disease Control and Prevention (CDC)-based CFS/ME symptom questionnaires. Circulating plasma pro-inflammatory cytokine levels were measured by ELISA. Multiple regression analyses examined associations between sleep, cytokines and symptoms, controlling for age, education, and body mass index. Results - Poor sleep quality (PSQI global score) was associated with greater pro-inflammatory cytokine levels: interleukin-1β (IL-1β) (β = 0.258, p = 0.043), IL-6 (β = 0.281, p = 0.033), and tumor ...
Amarkand tubers are routinely used by many Indian tribes as a specialized food for health and longevity but so far there is no scientific evidence for their activities. Taxonomically, Amarkand belong to genera Eulophia and Dioscorea. In this communication, comparative antifatigue potential of Amarkand was analyzed using forced swimming model in rats and evaluated using biomarkers of physical fatigue. Methanol extracts of tubers of D. bulbifera, E. ochreata, E. leghapanensis and bulbils of D. bulbifera exhibited rich polyphenolic content. D. bulbifera bulbils and E. ochreata significantly prolonged the swimming endurance time. Creatine kinase and urea nitrogen were significantly reduced by treatment of D. bulbifera bulbils and E. ochreata as compared to negative control. D. bulbifera bulbils effectively increased creatine (p < 0.001), lactate dehydrogenase (p < 0.01) and hemoglobin (p < 0.001) compared to negative control. D. bulbifera bulbils and E. ochreata treatments significantly increased glycogen
Chronic fatigue syndrome (CFS) is characterized by unexplained fatigue lasting for more than 6 months and accompanied by flulike symptoms. It most commonly affects women aged between 30 and 60 years. To date, clear diagnostic criteria allowing for unambiguous diagno-sis of CFS have not been established. We present a case of a 57-year-old woman with chronic fatigue syndrome in order to showcase the symptoms of this condition and propose a diagnos-tic protocol ...
In metal fatigue, it is common practice to distinguish between high-cycle fatigue (i.e. failure occurring after 10000-100000 cycles) and low-cycle fatigue. For elastic-plastic materials, there is an established correlation between fatigue and energy dissipation. In particular, high-cycle fatigue occurs when the energy dissipation remains bounded in time. Although the physical mechanisms in shape-memory alloys (SMAs) differ from plasticity, the hysteresis that is commonly observed in the stress-strain response shows that some energy dissipation occurs. It can be reasonably assumed that situations where the energy dissipation remains bounded are the most favorable for fatigue durability. In this communication, we present a direct method for determining if the energy dissipation in a SMA structure (submitted to a prescribed loading history) is bounded or not. That method is simple to use and could be relevant for the design of SMA systems with high durability requirements, such as stents. Some numerical
Looking for online definition of Cage Layer Fatigue in the Medical Dictionary? Cage Layer Fatigue explanation free. What is Cage Layer Fatigue? Meaning of Cage Layer Fatigue medical term. What does Cage Layer Fatigue mean?
Bennett RM. Fibromyalgia, chronic fatigue syndrome, and myofascial pain. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 274. Engleberg NC. Chronic fatigue syndrome. In: Bennett JE, ed. Mandell, Douglas, and Bennetts Principles and Practice of Infectious Diseases . 8th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2015:chap 133. IOM (Institute of Medicine). Beyond myalgic encephalomyelitis/chronic fatigue syndrome: redefining an illness. Washington, DC: The National Academies Press; 2015. www.nationalacademies.org/hmd/~/media/Files/Report%20Files/2015/MECFS/MECFS_ReportBrief.pdf . Accessed April 20, 2016. Nijs J, Roussel N, Van Oosterwijck J, et al. Fear of movement and avoidance behaviour toward physical activity in chronic-fatigue syndrome and fibromyalgia: state of the art and implications for clinical practice. Clin Rheumatol . 2013;32(8):1121-1129. PMID: 23639990 www.ncbi.nlm.nih.gov/pubmed/23639990 . Santhouse AM, ...
Most of us heard about chronic fatigue syndrome and its effects on todays public health. This health condition is considered a curse of our times, and a great deal of people around the world are affected by it. It is estimated that about a quarter of million Brits are currently suffering from this ailment. Chronic fatigue syndrome is considered a complex disease which is linked to a constant feeling of tiresome and exhaustion which do not go away with rest or sleep. Sometimes the symptoms go really bad and it becomes difficult to even carry out small daily tasks, but usually the condition tends to improve over time.. Actually, chronic fatigue syndrome is a lot more than just feeling tired, but also coping with a wide range of other signs and symptoms. This health condition can make a person suffer from the symptoms for years, and looking for ways of managing these symptoms in order to go on leading a normal life. Fortunately, in overwhelming majority of cases this disease is moderate and mild, ...
When present, symptoms vary but may include breathing problems; fatigue; glomerulonephritis; joint pain or muscle pain; purpura ...
It consists of five domains of the frailty phenotype: •Fatigue •Loss of appetite •Grip strength •Functional difficulties • ... also known as muscle fatigue, (or "lack of strength") refers to the inability to exert force with one's skeletal muscles. ...
"Fatigue". Archived 2011-06-29 at the Wayback Machine. 2001. "Fatigue" Figure 3.9 Bhandari, V. B. (2007). Design of Machine ... "Fatigue of metals" Archived 2013-01-02 at the Wayback Machine. 2007. Herbert J. Sutherland and John F. Mandell. "Optimized ... The general trend given by the Goodman relation is one of decreasing fatigue life with increasing mean stress for a given level ... Mars, W.V., Computed dependence of rubber's fatigue behavior on strain crystallization. Rubber Chemistry and Technology, 82(1 ...
Fatigue. The Unidimensional Fatigue Impact Scale (U-FIS) was developed in 2009 by Galen Research primarily for the measurement ... It has been translated into 14 languages and also been used in an investigation of fatigue, sleep loss and mood for patients ... Elbers RG, Rietberg MB, van Wegen EE, Verhoef J, Kramer SF, Terwee CB, Kwakkel G (August 2012). "Self-report fatigue ... It has been recommended for use in determining fatigue by an independent clinical research study and translated into eight ...
Fatigue. Undue haste. Lack of situational awareness, inattention. Misplaced motivation. Excessive task loading. Pre-existing ... which emphasizes in-water skills and comfort Medical examinations to ensure no hidden contraindications to diving Fatigue ...
Symptoms of diphtheria include fever of 38 °C (100.4 °F) or above; chills; fatigue; bluish skin coloration (cyanosis); sore ...
To treat mental fatigue, one must figure out what is causing the fatigue. Once the cause of the stress has been identified the ... Mental fatigue arises when an individual becomes involved in a complex task but does no physical activity and is still worn out ... Mental fatigue can affect an individual's life by causing a lack of motivation, avoidance of friends and family members, and ... Most of the time mental fatigue can be fixed by a simple life change like being more organized or learning to say no. According ...
... fatigue; loss of motivation; stomach problems; eating disorders (such as weight loss or gain); alcoholism; feeling betrayed, ...
Miller, James C. (2001). Fatigue. Controlling Pilot Error. New York, NY: McGraw-Hill. ISBN 978-0-071374-12-5. Mueller, Robert ( ...
Fatigue. The crisis of meaning…. nothing exists except for selling and buying. When there is talk of theories, I always think ...
... battle fatigue; disease not directly caused by enemy agents; accidents, to include explosive, aircraft, vehicular, and other ...
Fatigue 689. Refreshment 690. Agent 691. Workshop 2. Complex Voluntary Action 692. Conduct 693. Direction 694. Director 695. ...
864-867 L.B. Krupp, C. Christodoulou Fatigue in multiple sclerosis Curr Neurol Neurosci Rep, 1 (2001), pp. 294-298 "Preventing ... employee fatigue; failing eyesight / use of bifocals; inappropriate, loose, or poor-fitting footwear Preventive measures: ...
Drew, C.D. (1942). Mental fatigue. Flying Personnel Research Committee, Report No. 227. Drew, C.D., Colquhoun, W.P., & Long, H. ...
Chronic fatigue. Rapid mood swings. Orange discoloration of the skin, particularly the feet (Carotenosis). Having severe muscle ... A significant drop in potassium can cause abnormal heart rhythms, constipation, fatigue, muscle damage and paralysis. Signs and ... Extraintestinal presentations include anemia, osteoporosis, dermatitis herpetiformis, short stature, delayed puberty, fatigue, ... and symptoms include fatigue and weakness. Orthostatic hypotension, a marked decrease in blood pressure when standing from a ...
"Adrenal Fatigue , Hormone Health Network". www.hormone.org. Retrieved 30 October 2020. "AAFP: Functional Medicine lacks ... such as adrenal fatigue and numerous imbalances in body chemistry. Joe Pizzorno, a major figure in functional medicine, ... fatigue, food allergies, mercury exposure, kidney disorders, and rheumatoid arthritis. The companies were forced to pay a $ ...
... and fatigue. The presence of Formaldehyde, phthalates, and toluene (the toxic trio) in the work environment play a role in the ...
Subaru: EyeSight Driver Assist Škoda: iBuzz Fatigue Alert (available on most models since 2013 onwards) Volkswagen: Fatigue ... Driver Monitoring System (Toyota) Fatigue detection software "DRIVER FATIGUE AND ROAD ACCIDENTS A LITERATURE REVIEW and ... both evaluate driving technique for signs of driver fatigue. When the feature determines if the driver is fatigued, the message ... Various studies have suggested that around 20% of all road accidents are fatigue-related, up to 50% on certain roads. Some of ...
Jones, Heddwyn (2004-10-06). "Battle fatigue". Herald Sun. p. C04. "Anachronox Editing Tools and Docs v1.2". FilePlanet. 2001- ...
"Fatigue Mountain". BC Geographical Names. "Citadel Peak". BC Geographical Names. "Golden Mountain". BC Geographical Names. " ...
Dion, Jean (2014-06-04). «L'élément fatigue». Le Devoir (Montréal, Canada). Au revoir, Expos: Top 10 Moments. - Canadian ...
CS1 maint: discouraged parameter (link) Mintchell, Frederick (August 10, 2016). "Blockbuster fatigue? Check out some of these ...
La, Paul R. (January 16, 2007). "'Idol' fatigue? Think again". CNN. Retrieved August 6, 2011. Gorman, Bill (May 23, 2012). "FOX ...
Fatigue (lassitude). Systemic symptoms such as fever, night sweats, and weight loss are known as B symptoms; thus, presence of ... Furthermore, aerobic physical exercises probably reduce fatigue. The evidence is very uncertain about the effect on anxiety and ...
"Warning Fatigue". freedom-to-tinker.com. Media related to Vulnerability (computing) at Wikimedia Commons Security advisories ... a user to make a security decision without giving the user enough information to answer it Race Conditions Warning fatigue or ...
"Zoom Fatigue? Try Houseparty". The New Yorker. Retrieved October 16, 2020. Burrows, Matt (March 28, 2020). "Houseparty: How an ...
2017) • "Digital Fatigue." American Book Review. (2016) • "Who's Afraid of Self-Publishing?" Notre Dame Review. (2016) • " ...
Eggers, Kerry (June 2, 2004). "Medal fatigue". Portland Tribune. Archived from the original on January 16, 2009. Retrieved ...
Adrenal fatigue. Drug test failure (depending on ingredients, and if a competing athlete in particular sports) Energy crash. ... Beta-alanine has been found to decrease fatigue during high-intensity exercise by increasing the muscle carnosine concentration ... "Effects of a Multi-Ingredient Preworkout Supplement Versus Caffeine on Energy Expenditure and Feelings of Fatigue during Low- ... "Effects of supplementation with branched chain amino acids and ornithine aspartate on plasma ammonia and central fatigue during ...
Fatigue Lab. Certification Lab. Material Lab. Component Lab. Homologation Tracks. Four wheeler manufacturers/Commercial vehicle ...
If endometriosis is causing you to experience symptoms like fatigue, know that you arent alone. Heres what you can do to help ... Accepting that fatigue may impact your day is key. For Jessica, that fatigue usually sets in around 6 pm. For you, it may be a ... Can I Be Tested for Adrenal Fatigue?. Some healthcare providers subscribe to the theory of a condition known as adrenal fatigue ... Endometriosis Fatigue: Why It Happens and What You Can Do. Medically reviewed by Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC ...
Chronic Fatigue Syndrome is a chronic illness characterized by extreme fatigue that lasts for more than six months. Heres the ... Causes of Chronic Fatigue Syndrome. We still know very little about chronic fatigue, and sadly, the cause is still unknown. ... Chronic Fatigue Syndrome is a chronic illness characterized by extreme fatigue that lasts for more than six months. This ... Chronic Fatigue Syndrome Symptoms. While the term "chronic fatigue" is fairly descriptive of this crippling illness, it doesnt ...
Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a debilitating disorder linked to diverse intracellular ... Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a debilitating disorder linked to diverse intracellular ... Myalgic encephalomyelitis/chronic fatigue syndrome. J Chronic Fatigue Syndr (2003) 11(1):7-115. doi:10.1300/J092v11n01_02 ... Psychobehavioral and immunological characteristics of adult people with chronic fatigue and patients with chronic fatigue ...
Listener fatigue (also known as listening fatigue or ear fatigue) is a phenomenon that occurs after prolonged exposure to an ... Long-term fatigue[edit]. Long-term fatigue is defined as full recovery from temporary threshold shifts taking at least several ... Listener fatigue is not a clinically recognized state, but is a term used by many professionals. The cause for listener fatigue ... Temporary threshold shifts can result in different types of fatigue. Short-term fatigue[edit]. Recovery from temporary ...
Static fatigue is also found in this embrittlement form, such as the moisture-enhanced static fatigue of glass,[3] hydrogen ... It is often manifested by static fatigue. For example, as shown in Figure 1,[2] in a test of the static fatigue of a 2024 ... Furthermore, the static fatigue limit is observed. Kinetics[edit]. The strength vs. temperature plot of glass exposed in air is ... Static fatigue describes the fracture happening at a stress level less than the value required to cause ordinary tensile ...
Muscle fatigue, for example, results when the contractile properties of muscle are reduced, and continued exertion is ... fatigue. fatigue, in physiology, inability to perform reasonable and necessary physical or mental activity. Muscle fatigue, for ... If excessive fatigue occurs over a prolonged period, exhaustion (marked loss of vital and nervous power) may result. In most ... A new explanation of muscle fatigue suggests that it is related to the control of the flow of the calcium ions in muscle. The ...
Find out about some of the common and uncommon causes of fatigue and how to help yourself. ... One disorder that causes extreme fatigue is chronic fatigue syndrome (CFS). This fatigue is not the kind of tired feeling that ... Fatigue (PDQ)-Patient Version (National Cancer Institute) Also in Spanish * Fatigue and Multiple Sclerosis (National Multiple ... Fatigue Fighters in Sjogrens Syndrome (Sjogrens Syndrome Foundation) - PDF * Is Fatigue a Common Crohns Disease Symptom? ...
In order to help pilots avoid flying fatigued, NIOSH recently completed a fatigue prevention training for commercial pilots in ... Fatigue is a general lack of alertness and degradation in mental and physical performance, and can affect pilot alertness, ... Pilot fatigue has been documented as early as 1927 when Charles Lindbergh crossed the Atlantic Ocean. The National ... The training can be downloaded here: Fatigue Prevention for Pilots: A Training Program for Commercial Pilots in Alaska ...
Fatigue can result when you do not get enough sleep or do not get quality sleep. It can impair your driving, similar to alcohol ... Watch yourself and your co-workers for signs of fatigue.. *Report instances of fatigue in yourself and others to your direct ... Speak honestly if you are questioned about a fatigue-related incident. Fatigue is a normal biological response - it is not a ... Give supervisors and workers fatigue-symptom checklists and encourage self-reporting.. *Encourage peer monitoring of fatigue ...
... (CFS) is a complicated disease for doctors to diagnose - and even fully understand. Find out more ... also known as chronic fatigue syndrome (CFS). Contact CFIDS at: Chronic Fatigue and Immune Dysfunction Syndrome Association of ... Chronic Fatigue Syndrome. Resources. Please Note: By clicking a link to any resource listed on this page, you will be leaving ... The CFIDS Association of America is a charitable organization dedicated to conquering chronic fatigue and immune dysfunction ...
What is Fatigue?. World-renowned muscle fatigue researchers, Roger Enoka and Doug Stuart (1992), describe fatigue as an over- ... Getting the Facts on Fatigue. By Len Kravitz, PhD. Introduction. To the exerciser, the word fatigue denotes many different ... What are the Mechanisms for Sex Differences in Fatigue?. The main area of muscle fatigue difference in men and women is in the ... How Does the Brain Influence Fatigue?. As noted earlier in the column, central fatigue (the activation signal originating from ...
At least 1 million people in the United States have chronic fatigue syndrome, a condition that makes it difficult to perform ... Fatigue is a common symptom of illness and many patients are seen prior to a full 6 months of illness (prolonged fatigue). ... Although chronic fatigue syndrome (CFS) was first named in the 1980s, it is not a new disease and has been referred to by other ... Kids sometimes use fatigue as an excuse to avoid school or other activities. Many teens are overly active in a number of sports ...
Fatigue and muscle weakness can be reversed. Youll need resistance (or weights) to help rebuild lost muscle. It takes time and ... A: The problem you describe is common in people with fibromyalgia, but feelings of fatigue and weakness can occur in anyone who ... Among my most troublesome problems are fatigue and muscle weakness, which my doctor attributes to lack of physical activity. ...
At its worst, cancer-related fatigue is a draining, unrelenting exhaustion that impedes the ability to enjoy life and carry out ... Fatigue is by far the most common - and for many the most distressing - symptom affecting people with cancer. ... Fatigue. Fatigue is by far the most common symptom affecting people with cancer. For some, it is the most distressing symptom. ... Managing Fatigue. Tell your treatment team about your fatigue. They can suggest ways to help you feel better. There are many ...
Those suffering with symptoms of depression, anxiety, fatigue and blood pressure problems seem to drastically decline, if not ... Those suffering with symptoms of depression, anxiety, fatigue and blood pressure problems seem to drastically decline, if not ... fatigue, higher risk of heart attack and stroke, memory loss, as well as irritability and even death. Dental Sleep Medicine ... and nearly eliminated her depression as well as extreme fatigue. She later told me her depression was most likely due to her ...
Other dietary reasons for fatigue include too much alcohol (which is a depressant) and lack of certain vitamins and minerals. ... Certain diseases, medications, stress, and inadequate sleep and exercise can contribute to fatigue. ...
... buzzing in ears fatigue, excessive fatigue in elderly, best medications for tinnitus, low blood pressure fatigue weight loss, ... causes for chronic fatigue, ringing in ear problem, ... However, persistent fatigue or fatigue that occurs for no ... Chronic fatigue syndrome which occurs for no clearly identifiable reason may also lead to extreme fatigue despite the absence ... and keeping physically active may play a major role in counteracting fatigue. In all these contexts, fatigue is seen as a ...
Health Information on Fatigue: MedlinePlus Multiple Languages Collection ... Getting Help for Fatigue - English PDF Getting Help for Fatigue - 简体中文 (Chinese, Simplified (Mandarin dialect)) PDF ... Getting Help for Fatigue - English PDF Getting Help for Fatigue - Kreyol ayisyen (Haitian Creole) PDF ... Getting Help for Fatigue - English PDF Getting Help for Fatigue - Wikang Tagalog (Tagalog) PDF ...
A few years ago my sister bought me, as a birthday present, the actual issue of the London Sunday Times for the day of my birth, June 3, 1945. I have the paper in front of me right now, discolored and rather fragile - a little slice of the world ...
But there are things you can do to help fight fatigue. Here are 7 tips to help manage cancer-related fatigue. ... There is no way to know whether you will have fatigue or how bad it will be. ... Describing fatigue. No lab tests or x-rays can diagnose or show your level of fatigue. The best measure of fatigue comes from ... Managing your fatigue. Heres a recap of things you can do to help manage and reduce your fatigue:. *Balance rest and activity ...
Professor, have you observed any combat fatigue from people who have watched too many war programs on television? ... How much knowledge can we absorb without suffering from cable fatigue? I asked him. ...
Chronic fatigue syndrome and fibromyalgia. Earlier fatigue was classified into Chronic fatigue syndrome that was considered an ... Fatigue too depends on the patient perception.. Existing fatigue measures include Multidimensional Fatigue Inventory (MFI) and ... Why does fatigue occur in fibromyalgia patients?. It is unknown why fatigue occurs in fibromyalgia patients. There is evidence ... Fatigue measures and patient perception. Pain measurement of fibromyalgia relies on patient report and his or her perception of ...
A report to the CAA last week highlighted a case of fatigue involving pilots aboard a UK-operated passenger Airbus, and today ... requirements are there to ensure that pilot and other crew members do not operate aircraft with unsafe levels of fatigue. ... than current requirements by obliging airlines to plan rotas and manage crew duties to actively address the risk of fatigue ...
Millions of viewers across the country will tune in Wednesday night to watch Hillary Clinton and Donald Trump spat over immigration, the national debt and their fitness. And millions more will likely tune it out.
Chronic fatigue syndrome. BMJ 1996; 313 doi: https://doi.org/10.1136/bmj.313.7061.831 (Published 05 October 1996) Cite this as ...
The prognosis of chronic fatigue and chronic fatigue syndrome: a systematic review. Q J Med 1997; 90: 223-233. ... Definition Chronic fatigue syndrome is characterised by severe, disabling fatigue and other symptoms, including musculoskeletal ... Aetiology The cause of chronic fatigue syndrome is poorly understood.. Prognosis Studies of prognosis in chronic fatigue ... The prevalence and morbidity of chronic fatigue and chronic fatigue syndrome: a prospective primary care study. Am J Public ...
Fatigue from the rigors of using an exoskeleton has been a problem for many. Now a team at the University of Pittsburgh wants ... Ultrasound is used to take measurements of muscles and create a model for muscle fatigue through the signals it receives. "We ... Reducing Exoskeleton Muscle Fatigue. Nov 15, 2017. by Eric Butterman ASME.org ... Nitin Sharma (left) and his colleagues are developing an exoskeleton that utilizes ultrasound sensors for measuring fatigue. ...
... but the reason behind it is decision fatigue, as outlined in this thought-provoking article from the New York Times. ... What Is Decision Fatigue?. In its simplest terms, decision fatigue refers to the idea that people tend to make worse decisions ... The best solution for decision fatigue is the same as any other type of fatigue-rest. Nothing can beat a good nights sleep for ... How Decision Fatigue Zaps Your Willpower (and What You Can Do About It). Making decisions and resisting temptations are hard at ...
There may be other associated symptoms related to the underlying cause of the chronic fatigue. ... Learn about the symptoms of fatigue such as feeling weak, being constantly tired, or lacking energy. ... Treatment of fatigue is generally directed toward the condition or disease that is causing the fatigue. Read more: Fatigue ... Sometimes fatigue is described as feeling a lack of energy and motivation (both mental and physical). The causes of fatigue are ...
... chances are youre also fighting fatigue. Fatigue is the most common side effect of cancer treatment, and it often hits without ... What Is Cancer-related Fatigue?. The fatigue that comes with cancer, called cancer-related fatigue, is different from the ... Fatigue is often caused by more than one thing. Some of the more common causes of cancer-related fatigue are:. Anemia. There ... Managing fatigue is part of good cancer care. Work with your cancer care team to find and treat the causes of your fatigue. ...
  • Chronic fatigue is another common symptom you may encounter, though it hasn't been supported by much formal research. (healthline.com)
  • Is Fatigue a Common Crohn's Disease Symptom? (medlineplus.gov)
  • Also, continuous fatigue should have been the first noticeable symptom of illness. (kidshealth.org)
  • Fatigue is a common symptom of illness and many patients are seen prior to a full 6 months of illness (prolonged fatigue). (kidshealth.org)
  • Fatigue is by far the most common symptom affecting people with cancer. (nccn.org)
  • Fatigue is an early symptom of leukemia-a cancer that starts in bone marrow. (nccn.org)
  • However, persistent fatigue or fatigue that occurs for no clearly identifiable reason and continues even with the rest that is considered to be a symptom of some underlying disease. (amazonaws.com)
  • According to the 2010 American College of Rheumatology (ACR) criteria for diagnosis of fibromyalgia , fatigue forms an important symptom of fibromyalgia. (news-medical.net)
  • About half of people with PD report fatigue is a major problem and a third say it is their most disabling symptom. (parkinson.org)
  • Fatigue is also a symptom of depression, but a person can be fatigued without being depressed. (parkinson.org)
  • Understanding fatigue as a symptom of PD and finding ways to cope with it are essential to maintaining a good quality of life. (parkinson.org)
  • Fatigue (either physical, mental or both) is a symptom that may be difficult for the patient to describe and words like lethargic, exhausted and tired may be used. (medicinenet.com)
  • Taking a careful and complete history is the key to help making the underlying diagnosis of the cause for the symptom of fatigue . (medicinenet.com)
  • Fatigue is a very common complaint and it is important to remember that it is a symptom and not a disease. (medicinenet.com)
  • Often, the symptom of fatigue has a gradual onset and the person may not be aware of how much energy they have lost until they try to compare their ability to complete tasks from one time frame to another. (medicinenet.com)
  • They may presume that their fatigue is due to aging and ignore the symptom. (medicinenet.com)
  • Fatigue is mainly a symptom and not a disease in itself. (medicinenet.com)
  • Fatigue is the most common symptom for people with cancer and the most common side effect of cancer treatment. (cancer.ca)
  • Currently, chronic fatigue syndrome cannot be identified by any specific physical symptom or test and diagnosis is therefore based on a pattern of symptoms and the exclusion of other possible causes. (news-medical.net)
  • Fatigue can be a symptom of iron-deficiency anemia , which is common in pregnancy. (babycenter.com)
  • Penner IK, Paul F (2017) Fatigue as a symptom or comorbidity of neurological diseases. (springer.com)
  • This study investigated chronic fatigue as a symptom of type 1 diabetes and not " chronic fatigue syndrome ," in which the fatigue is not associated with any known medical condition, Dr. Knoop clarified for Medscape Medical News . (medscape.com)
  • Once the fatigue is triggered, other factors step in and can perpetuate the symptom. (medscape.com)
  • Sometimes the fatigue increase from anti-depressants (or other medications) is only a temporary symptom that stabilizes as you take the medication long enough. (drugs.com)
  • Fatigue can be a symptom of the cancer itself or that the cancer is growing or spreading. (cancer.net)
  • Chronic fatigue is a symptom of many diseases and conditions. (wikipedia.org)
  • At its worst, cancer-related fatigue is a draining, ongoing exhaustion that limits one's ability to enjoy life and do activities. (nccn.org)
  • Cancer-related fatigue generally occurs when cancer spreads to bone marrow and causes anemia. (nccn.org)
  • More information on fatigue can be found in the NCCN Clinical Practice Guidelines in Oncology for Cancer-Related Fatigue. (nccn.org)
  • The fatigue that comes with cancer, called cancer-related fatigue , is different from the fatigue of daily life. (cancer.org)
  • Cancer-related fatigue is not the tired feeling people remember having before they had cancer. (cancer.org)
  • Here are some signs of cancer-related fatigue that you and your family can watch for. (cancer.org)
  • How long does cancer related fatigue last? (cancer.org)
  • Cancer-related fatigue can last from months to years. (cancer.org)
  • What causes cancer-related fatigue? (cancer.org)
  • The causes of cancer-related fatigue are not fully understood. (cancer.org)
  • Tumor-assoziierte Fatigue (Cancer-related Fatigue [CrF]) tritt bei vielen Krebspatienten w hrend und nach der Behandlung auf. (aerzteblatt.de)
  • Im internationalen Sprachgebrauch hat sich f r ein solches M digkeits- und Ersch pfungssyndrom, wenn es bei Krebspatienten auftritt, der Begriff Tumor-assoziierte Fatigue (Cancer-related Fatigue [CrF]) etabliert ( 1 ). (aerzteblatt.de)
  • High doses of the herb American ginseng (Panax quinquefolius) over two months reduced cancer-related fatigue in patients more effectively than a placebo , a Mayo Clinic-led study found. (medicalnewstoday.com)
  • The cause of cancer-related-fatigue (CRF) is not fully understood. (macmillan.org.uk)
  • As many as 9 out of 10 people with cancer (90%) get cancer-related fatigue (CRF). (macmillan.org.uk)
  • Cancer-related fatigue usually gets better after treatment finishes. (macmillan.org.uk)
  • Cancer-related fatigue may also make tiredness caused by other conditions worse. (macmillan.org.uk)
  • If you are older you are more likely to be affected by cancer-related fatigue. (macmillan.org.uk)
  • The medical term for this is "cancer-related fatigue. (cancer.net)
  • Cancer-related fatigue can affect your daily life. (cancer.net)
  • For some people, cancer-related fatigue is a minor side effect. (cancer.net)
  • How is cancer-related fatigue diagnosed? (cancer.net)
  • How is cancer-related fatigue managed? (cancer.net)
  • Sufferers of chronic fatigue syndrome also experience significant alterations in levels of irritability, mood swings, panic attacks, anxiety and depression. (draxe.com)
  • Antidepressants aren't recommended to treat fatigue in cancer patients although they may help treat depression and anxiety. (nccn.org)
  • Depression, High Blood Pressure, Fatigue? (prweb.com)
  • Those suffering with symptoms of depression, anxiety, fatigue and blood pressure problems seem to drastically decline, if not disappear. (prweb.com)
  • The side effects associated with OSA span from depression, high blood pressure, fatigue, higher risk of heart attack and stroke, memory loss, as well as irritability and even death. (prweb.com)
  • Those suffering with symptoms of depression, anxiety, fatigue and blood pressure problems seem to drastically decline, if not disappear," says Dr. Tache on successfully treating OSA to overcome other health issues. (prweb.com)
  • This treatment brought her apnea down to safe levels, and nearly eliminated her depression as well as extreme fatigue. (prweb.com)
  • Cancer pain can make you less active, make you not want to eat, cause sleep problems, and cause depression - all of which can lead to fatigue. (cancer.org)
  • Depression and anxiety are common types of distress that can cause or worsen fatigue. (cancer.org)
  • Just when you thought your privacy couldn't be invaded anymore, a team of researchers are working on a device for NASA that would be able to detect brain injury, stress, fatigue and depression. (wired.com)
  • While it is true that depression and other psychiatric issues may be the reason for fatigue, it is reasonable to make certain that there is not an underlying physical illness that is the root cause. (medicinenet.com)
  • Depression can also cause fatigue or sleeplessness, so if you feel sad, hopeless, or unable to handle your daily responsibilities, or if you have thoughts of harming yourself, call your doctor or midwife immediately. (babycenter.com)
  • In patients who are not anemic the fatigue is due to infection, depression, side effect of chemo drugs, or low platelets or low WBC. (medhelp.org)
  • Diagnosis must first rule out known causes of fatigue such as hypothyroidism, cancer, multiple sclerosis, and major depression with psychotic or melancholic features (e.g., schizophrenia, bipolar disorder). (infoplease.com)
  • Multiple regression analyses revealed several independent associates of fatigue, including depression (all fatigue scales), MGFA stage (FSS, physical FIS), female sex (cognitive and psychosocial FIS), and sleep debt (physical FIS). (springer.com)
  • Cognitive fatigue in MG may not be a direct disease manifestation, but secondary to depression. (springer.com)
  • Fatigue can be made worse by other side effects such as pain, depression, and anemia. (breastcancer.org)
  • Conditions such as anxiety, depression and stress can make fatigue worse. (macmillan.org.uk)
  • If you have not yet done this get your blood tested which could show why you have chronic Fatigue unless it is from depression. (drugs.com)
  • Managing stress and treating depression and anxiety can reduce your fatigue. (cancer.net)
  • Fatigue may be attributable to such conditions as stress, sleep apnoea, anaemia, thyroid illness, depression, and the side effects of some medications. (infobarrel.com)
  • The evidence of ROS having a causal influence to fatigue has been shown in small muscles, at the neuromuscular junction and in whole-body exercise (like running) by elite athletes (Reid). (unm.edu)
  • Ultrasound is used to take measurements of muscles and create a model for muscle fatigue through the signals it receives. (asme.org)
  • The hope is that using ultrasound, which supplies image-based, real-time image sensing , the exoskeleton will better sense fatigue and will know when to switch from joint actuators to electrical stimulation of the muscles themselves, something that has been difficult to determine to this point. (asme.org)
  • With physical fatigue , your muscles cannot do things as easily as they used to. (thebody.com)
  • Q: You've talked about fatigue in the muscles and vocal fold tissues. (uiowa.edu)
  • Although they've been studied less, joints, cartilage, tendons and ligaments of the vocal system seem to be less prone to fatigue as compared to muscles and vocal fold tissues. (uiowa.edu)
  • Q: You implied that the circulatory system helps vocal muscles recover from fatigue pretty quickly. (uiowa.edu)
  • Q: Okay, so muscles recover quicker, but are they more prone to fatigue than tissues are? (uiowa.edu)
  • Whispering is essentially talking without vibration of the vocal folds, and if the vocal muscles are fatigued, whispering won't allow them to rest. (uiowa.edu)
  • For example, muscles fatigue if the are called upon to repetitively work for an extended period. (yahoo.com)
  • Being too inactive may make your muscles become weaker (deconditioning) and make fatigue worse. (macmillan.org.uk)
  • As a relative newbie to weightlifting (have lifted for many years, bet never seriously) I have a pretty basic question: At what point shoule I recognize when my muscles are fatigued enough so that I can't do one more rep? (exrx.net)
  • This oxygen is the fuel for muscles, and low levels of it can lead to fatigue. (oncolink.org)
  • Physical fatigue is the transient inability of muscles to maintain optimal physical performance, and is made more severe by intense physical exercise. (wikipedia.org)
  • Physical fatigue, or muscle fatigue, is the temporary physical inability of muscles to perform optimally. (wikipedia.org)
  • If excessive fatigue occurs over a prolonged period, exhaustion (marked loss of vital and nervous power) may result. (infoplease.com)
  • When they exercise or try to be active in spite of their fatigue, people with CFS experience debilitating exhaustion that can confine them to bed for days. (encyclopedia.com)
  • The extreme exhaustion that comes with fatigue can lead people to reduce hours at work or retire, or avoid social activities. (parkinson.org)
  • However, at eight weeks, ginseng offered cancer patients significant improvement in general exhaustion - feelings of being "pooped," "worn out," "fatigued," "sluggish," "run-down," or "tired" - compared to the placebo group. (medicalnewstoday.com)
  • Definition Fatigue is physical and/or mental exhaustion that can be triggered by stress , medication, overwork, or mental and physical illness or disease. (yahoo.com)
  • Chronic Fatigue Syndrome (ME/CFS) describes a sense of exhaustion and post-exertion malaise, even when you have gotten enough rest and sleep. (dailystrength.org)
  • The disease is characterized by six months of incapacitating fatigue experienced as profound exhaustion and extremely poor stamina, and problems with concentration and short-term memory. (dailystrength.org)
  • Fatigue is a feeling of tiredness or exhaustion. (macmillan.org.uk)
  • Fatigue can cause physical, emotional, and mental exhaustion. (oncolink.org)
  • Two widely used definitions of chronic fatigue syndrome (from the US Centers for Disease Control and Prevention 1 and from Oxford 2 -see table) were developed as operational criteria for research. (bmj.com)
  • But it's only in the past decade that chronic fatigue syndrome has received serious recognition by federal agencies like the U.S. Centers for Disease Control and Prevention and the National Institutes of Health . (sfgate.com)
  • Yet the national Centers for Disease Control and Prevention now calls chronic fatigue syndrome a very real and debilitating condition - and a significant public health threat. (sunjournal.com)
  • One of the main symptoms of anemia is fatigue. (healthline.com)
  • In some instances this abnormal fatigue may be associated with systemic disorders such as anemia, a deficiency of protein or oxygen in the blood, addiction to drugs, increased or decreased function of the endocrine glands, or kidney disease in which there is a large accumulation of waste products. (infoplease.com)
  • As a result, cancer treatments can induce anemia which can cause fatigue. (nccn.org)
  • Treatment of anemia with erythropoietin may help decrease fatigue. (nccn.org)
  • Cancer itself can cause fatigue by spreading to the bone marrow and causing a low red blood cell count (anemia). (cancer.org)
  • If you don't have enough red blood cells, or if they aren't carrying enough oxygen, your fatigue may be caused by anemia. (thebody.com)
  • Work with your doctor to identify and treat any medical causes of fatigue besides PD, such as anemia. (parkinson.org)
  • Examples of some treatable causes of fatigue include anemia , diabetes , thyroid disease , heart disease , COPD and sleep disorders (Table). (medicinenet.com)
  • Iron supplements can help with the fatigue that results from iron-deficiency anemia. (healthy.net)
  • There are two ways to treat fatigue that have proven effective in studies: exercise and treatment of anemia. (oncolink.org)
  • People with anemia may feel extreme and overwhelming fatigue. (cancer.net)
  • Severe fatigue is especially common around the time of her menstrual cycle. (healthline.com)
  • The elderly who have experience a decrease in certain hormone levels with age, like growth hormone and thyroid hormone, coupled with the prevalence of chronic disease in the senior years are therefore more likely to experience severe fatigue. (amazonaws.com)
  • People with CFS have severe fatigue that keeps them from performing their normal daily activities. (encyclopedia.com)
  • There exist two specific criteria that must be met for a diagnosis of CFS: (1) severe fatigue lasting six months or longer and (2) the coexistence of any four of a number of characteristic symptoms, defined as mild fever, sore throat , tender lymph nodes, muscle pain and weakness, joint pain, headache , sleep disorders, confusion, and memory loss. (britannica.com)
  • In the study, "chronic fatigue" was defined as severe fatigue lasting at least 6 months. (medscape.com)
  • A score of 35 or higher indicates severe fatigue. (medscape.com)
  • Muscle fatigue, for example, results when the contractile properties of muscle are reduced, and continued exertion is impossible unless the muscle is allowed to rest. (infoplease.com)
  • There are some persons in whom fatigue is a chronic state that does not necessarily result from activity or exertion. (infoplease.com)
  • Diagnosis also requires at least four of the following symptoms, each persistent or recurring and not present before the fatigue: impairment of short-term memory or concentration, sore throat, tender lymph nodes in the neck or axillary region, muscle pain, joint pain, headaches peculiar to the syndrome, unrefreshing sleep, and malaise of more than one day's duration following exertion. (infoplease.com)
  • Too much exertion is NOT good and can cause increased fatigue - so it's important to 'know your body' and be able to set appropriate limits. (drugs.com)
  • The patients initially reported their energy level and fatigue on exertion at baseline. (go.com)
  • The researchers found that statins were associated with both decreased energy level and increased fatigue with exertion. (go.com)
  • Although that diagnosis lead to a prescribed management plan, she still experiences symptoms like fatigue . (healthline.com)
  • The process for diagnosis usually begins with ruling out possible underlying diseases and chronic conditions … until the only choice left is chronic fatigue syndrome. (draxe.com)
  • Discuss the diagnosis process in finding a cause for your fatigue. (medicinenet.com)
  • Depending on your diagnosis, what was the treatment for your fatigue? (medicinenet.com)
  • In 2015, the National Academy of Medicine (formerly the Institute of Medicine (IOM)) Committee on Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome released a report that proposed new diagnostic criteria for CFS intended to improve diagnosis and care of those affected by CFS. (labtestsonline.org)
  • In addition, a diagnosis of CFS requires that the symptoms experienced cannot have predated the onset of fatigue and that all other illnesses or medical conditions capable of giving rise to these symptoms have been ruled out clinically. (britannica.com)
  • Brian's diagnosis was one even his mother was not expecting: chronic fatigue syndrome. (sunjournal.com)
  • The intensity and type of symptoms can vary from day to day and from person to person, but typically the extreme fatigue lasts at least 6 months or more. (labtestsonline.org)
  • It is usually when one or more of these processes are disrupted that persistent or uncharacteristic fatigue can set in. (amazonaws.com)
  • However, age does not bring about a persistent feeling of fatigue and a senior can be just as active and energetic then younger adults although this may be for shorter periods of time. (amazonaws.com)
  • Studies have shown that fatigue is more severe, constant or persistent and unpredictable than normal tiredness among fibromyalgia patients. (news-medical.net)
  • Because there is little formal research on endometriosis fatigue, it may be difficult to tell whether the gynecological condition is causing the persistent tiredness. (medicalnewstoday.com)
  • Chronic fatigue syndrome (CFS) , also called myalgic encephalomyelitis , disorder characterized by persistent debilitating fatigue . (britannica.com)
  • Prolonged fatigue is a self-reported, persistent (constant) fatigue lasting at least one month. (wikipedia.org)
  • Chronic fatigue may be either persistent or relapsing. (wikipedia.org)
  • The National Transportation Safety Board listed reduction of fatigue-related accidents on their list of Ten Most Wanted Transportation Safety Improvements for 2017-2018, and the Department of Transportation identified the issue of pilot fatigue as a top priority during a 2009 airline Safety Call to Action, following the crash of Colgan Air flight 3407. (cdc.gov)
  • Chronic Fatigue Syndrome is a chronic illness characterized by extreme fatigue that lasts for more than six months. (draxe.com)
  • One disorder that causes extreme fatigue is chronic fatigue syndrome (CFS). (medlineplus.gov)
  • Chronic fatigue syndrome which occurs for no clearly identifiable reason may also lead to extreme fatigue despite the absence of any known disease. (amazonaws.com)
  • Chronic fatigue syndrome (CFS) is a disorder that causes ongoing, extreme fatigue that is not explained by any known medical condition. (labtestsonline.org)
  • This means that someone with CFS may feel physical symptoms, such as being very tired and weak (extreme fatigue), headaches , or dizziness. (kidshealth.org)
  • Scientists have not yet identified what causes myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (cdc.gov)
  • Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a debilitating disorder linked to diverse intracellular infections as well as physiological stress. (frontiersin.org)
  • Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a heterogeneous disorder of unknown etiology. (frontiersin.org)
  • CFS is the most common name for this disorder, but it also has been called chronic fatigue and immune disorder syndrome (CFIDS), myalgic encephalomyelitis, low natural killer cell disease, post-viral fatigue syndrome, Epstein-Barr disease, and yuppie flu. (encyclopedia.com)
  • CFS or Chronic Fatigue Syndrome (also known as Myalgic Encephalomyelitis- ME and as Chronic Fatigue Immune Dysfunction Syndrome -CFIDS) as the name express, chronic means long term and fatigue means tiredness, is characterized by extreme tiredness that will not pass off by taking rest. (bartleby.com)
  • 1 ) report on a distinct metabolic signature present in patients who have myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) compared with healthy controls. (pnas.org)
  • Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a serious , poorly understood and often disabling disease . (yahoo.com)
  • Chronic fatigue syndrome (CFS), also referred to as myalgic encephalomyelitis (ME), is a complex, fatiguing, long-term medical condition that causes worsening symptoms after physical or mental activity, a greatly diminished capacity to accomplish tasks that had been routine prior to the illness, and unrefreshing sleep. (yahoo.com)
  • 2 There are actually a number of different names used for this condition, including myalgic encephalopathy/myalgic encephalomyelitis (ME), post-viral fatigue syndrome (PVFS) and chronic fatigue immune dysfunction syndrome (CFIDS). (mercola.com)
  • More than 2 million people in the United States have myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (pnas.org)
  • Myalgic Encephalomyeltis (or ME) and Post Viral Fatigue are synonyms for chronic fatigue syndrome . (everything2.com)
  • Listener fatigue (also known as listening fatigue or ear fatigue) is a phenomenon that occurs after prolonged exposure to an auditory stimulus . (wikipedia.org)
  • It is unknown why fatigue occurs in fibromyalgia patients. (news-medical.net)
  • Until this study, its effects had not been tested extensively against the debilitating fatigue that occurs in up to 90 percent of cancer patients. (medicalnewstoday.com)
  • Definition Chronic fatigue syndrome is characterised by severe, disabling fatigue and other symptoms, including musculoskeletal pain, sleep disturbance, impaired concentration, and headaches. (bmj.com)
  • Fatigue can cause headaches and difficulty concentrating. (medicalnewstoday.com)
  • I found no mention of fatigue or headaches after completion of taking either drug. (drugs.com)
  • Fatigue is a feeling of tiredness due to low energy levels and is accompanied usually by sleepiness and weakness. (amazonaws.com)
  • Fatigue is different from sleepiness. (parkinson.org)
  • Fatigue is often described as an uncomfortable tiredness, whereas sleepiness is comfortable and inviting. (yahoo.com)
  • In addition, research indicates that chronic fatigue syndrome may be linked to oxidative stress, Celiac disease, and food sensitivities or food allergies. (draxe.com)
  • Static fatigue describes the fracture happening at a stress level less than the value required to cause ordinary tensile fracture. (wikipedia.org)
  • This term highlights the contribution of environment to the crack propagation in materials under applied or residual stress , which leads to stress concentration and thus fatigue . (wikipedia.org)
  • For example, as shown in Figure 1, [2] in a test of the static fatigue of a 2024 aluminum coated with mercury , the alloy is subject to a stress level less than the value causing plastic flow , and the time it takes to fracture is measured. (wikipedia.org)
  • Usually a stress called static fatigue limit is present, representing the boundary below which the material does not fracture, no matter how long the test duration is. (wikipedia.org)
  • has been chosen as a topic for research is, Are social workers at a higher-risk for burnout and compassion fatigue because of job stress? (bartleby.com)
  • Stress can make fatigue worse. (parkinson.org)
  • To learn the difference between day-to-day stress and a medical condition that may be causing your fatigue, read on. (wikihow.com)
  • Fatigue in cancer patients has been linked to an increase in the immune system's inflammatory cytokines as well as poorly regulated levels of the stress-hormone cortisol. (medicalnewstoday.com)
  • Adrenal fatigue or hypoadrenia is a pseudo-scientific term used by alternative medicine providers to suggest that the adrenal glands are exhausted and unable to produce adequate quantities of hormones, primarily cortisol, due to chronic stress or infections. (yahoo.com)
  • This prolonged stress has now caused many people to experience crisis fatigue. (unh.edu)
  • But before we blame Frank's fatigue on stress, it's my job to make sure it's not anything more serious. (scientificamerican.com)
  • Metabolomics showed that chronic fatigue syndrome is a highly concerted hypometabolic response to environmental stress that traces to mitochondria and was similar to the classically studied developmental state of dauer. (pnas.org)
  • In addition to fracture toughness and strain gradient, these standards also present the procedures for determining K-R curves, stress-life and strain-life fatigue data, threshold stress intensity factors, and reference temperatures. (astm.org)
  • A realistic load spectrum - cyclic loads, stress levels, welding methods, surface roughness, etc. - is a key factor for an accurate estimate of the expected or residual fatigue life of any vessel. (dnv.com)
  • A superelastic endoprosthesis can have improved fatigue resistance, and improved resistance to crack formation by being configuring to have an austenitic finish temperature from about 5 degrees Celsius to about 35 degrees Celsius, a stress-strain curve having an upper plateau stress from about 40 ksi to about 80 ksi, and a lower plateau stress from about 5 ksi to about 50 ksi. (freepatentsonline.com)
  • Re ''A Postmodern Plague Ravages Japan's Workers'' (Saku Journal, Feb. 21): Using the terms chronic fatigue and chronic fatigue syndrome interchangeably fails to distinguish patients with tiredness, which can be caused by modern stress, from those with true chronic fatigue syndrome, which is a debilitating biological illness involving various infectious agents and the immune and central nervous systems. (nytimes.com)
  • This class will show that the basic principles of fatigue life estimation are relatively straightforward and certainly within the role of typical stress, dynamics, and FEA design engineers. (mscsoftware.com)
  • Allow yourself to rest, but do not overdo it as too much rest can make fatigue worse. (oncolink.org)
  • In its simplest terms, decision fatigue refers to the idea that people tend to make worse decisions after having made a lot of decisions. (lifehacker.com)
  • For people getting chemotherapy in cycles, fatigue often gets worse in the first few days and then gets better until the next treatment, when the pattern starts again. (cancer.org)
  • For those getting radiation , fatigue usually gets worse as the treatment goes on. (cancer.org)
  • One reason might be that fatigue sneaks up on us: it usually gets worse so slowly that we don't even notice. (thebody.com)
  • On top of this, it will leave you with almost no energy throughout your day, making your fatigue even worse! (wikihow.com)
  • For example, fatigue may be worse at the beginning and end of a chemotherapy treatment cycle and increase throughout the course of radiation treatment. (cancer.ca)
  • Your doctor will ask you questions about when your fatigue started, how long it has lasted, whether anything makes the fatigue better or worse and how the fatigue affects your daily life. (cancer.ca)
  • Your doctor will also look at anything that may be making the fatigue worse. (cancer.ca)
  • Many patients with cancer don't tell their doctors about their fatigue. (nccn.org)
  • Therapies that aim to educate patients about fatigue and related factors help reduce fatigue. (nccn.org)
  • Little research has been done to test medications for fatigue in patients with cancer. (nccn.org)
  • Fatigue is recognized as a part of the syndrome of symptoms that affect fibromyalgia patients. (news-medical.net)
  • Why does fatigue occur in fibromyalgia patients? (news-medical.net)
  • There is evidence that fatigue is the second most important parameter to measure after pain in fibromyalgia patients. (news-medical.net)
  • Fatigue management in patients with IBD: A randomized controlled trial. (mayoclinic.org)
  • After eight weeks, we saw a 20-point improvement in fatigue in cancer patients, measured on a 100-point, standardized fatigue scale," Dr. Barton says. (medicalnewstoday.com)
  • These patients believed the term fatigue trivializes the illness and discourages research into potential treatments. (yahoo.com)
  • The origin of fatigue may be associated with spinal cord lesions causing pain in NMO patients. (rxlist.com)
  • Are other low risk patients experiencing fatigue? (medhelp.org)
  • Yes, fatigue is a common complain in patients suffering from myelodysblastic syndromes. (medhelp.org)
  • Fatigue is likely one of the top 20 complaints that I hear from my patients. (scientificamerican.com)
  • We applied the 9-item Fatigue Severity Scale (FSS) and the 40-item Fatigue Impact Scale (FIS) to 73 MG patients and 230 age- and sex-matched control subjects. (springer.com)
  • All fatigue scores, with the exception of the cognitive FIS subscale, were higher in MG patients than controls. (springer.com)
  • The FSS and FIS represent reliable and validated tools, appropriate to discern meaningful clinical aspects of fatigue in MG. Clinical recognition of the complexity of fatigue may foster individualized treatment approaches for affected MG patients. (springer.com)
  • Dobkin BH (2008) Fatigue versus activity-dependent fatigability in patients with central or peripheral motor impairments. (springer.com)
  • Paul RH, Cohen RA, Goldstein JM, Gilchrist JM (2000) Fatigue and its impact on patients with myasthenia gravis. (springer.com)
  • Symonette CJ, Watson BV, Koopman WJ, Nicolle MW, Doherty TJ (2010) Muscle strength and fatigue in patients with generalized myasthenia gravis. (springer.com)
  • Askmark H, Haggård L, Nygren I, Punga AR (2012) Vitamin D deficiency in patients with myasthenia gravis and improvement of fatigue after supplementation of vitamin D3: a pilot study. (springer.com)
  • Because there is no drug to treat chronic fatigue syndrome, patients often are advised to seek behavioral therapy to learn to live with their condition. (sfgate.com)
  • Robert Miller started eating again earlier this month, after the U.S. secretary of health's office promised to participate in a meeting between the FDA and patients, doctors and drug manufacturers this spring to discuss research into chronic fatigue. (sfgate.com)
  • Many patients said they understand why the FDA rejected the drug, which may be effective in only a subset of chronic fatigue sufferers. (sfgate.com)
  • The clinical message is that the prevalence of chronic fatigue is high in diabetes and is burdensome for patients. (medscape.com)
  • Chronic fatigue was present in 40% of the type 1 diabetes patients compared with just 7% of the matched controls, a significant difference. (medscape.com)
  • Fatigue severity was also significantly higher among the type 1 diabetes patients, with an average CIS score of 31 vs just 17 in the controls. (medscape.com)
  • Patients who reported having neuropathy, nephropathy, or cardiovascular disease as complications of diabetes were also more likely to be chronically fatigued. (medscape.com)
  • Chronically fatigued type 1 diabetes patients were significantly more impaired compared with the other diabetes patients on all aspects of daily function, Dr. Knoop and colleagues note. (medscape.com)
  • In a substudy of 66 type 1 diabetes patients who wore continuous glucose monitors for 5 days, the 25 who were chronically fatigued spent less time in hypoglycemia compared with 41 patients who were not chronically fatigued, but there were no significant differences between the 2 groups in mean glucose, glycemic variability or time spent in hyperglycemia. (medscape.com)
  • Not all patients experience all symptoms although everyone experiences fatigue. (everything2.com)
  • This keeps the body safe from risks due to lack of movement and is shown to help fatigue levels, and pain levels for applicable patients. (drugs.com)
  • Besides crippling fatigue, patients may experience "brain fog," sleep disorders, muscle and joint aches, and tender lymph nodes. (sunjournal.com)
  • Yet now, "a not inconsequential number of patients [on statins] may experience fatigue and exercise intolerance. (go.com)
  • The hallmark symptoms of CFS are overwhelming fatigue and weakness that make it extremely difficult to perform routine and daily tasks, like getting out of bed, dressing, and eating. (kidshealth.org)
  • Among my most troublesome problems are fatigue and muscle weakness, which my doctor attributes to lack of physical activity. (arthritis.org)
  • The problem you describe is common in people with fibromyalgia , but feelings of fatigue and weakness can occur in anyone who is inactive - whatever the reason. (arthritis.org)
  • Chronic Fatigue Syndrome Thankfully, it is hard for most people to imagine a tiredness and weakness of body that would keep one confined to a bed. (bartleby.com)
  • Aside from drowsiness, other symptoms can be confused with fatigue including shortness of breath with activity and muscle weakness . (medicinenet.com)
  • Unlike weakness, fatigue can usually be alleviated by periods of rest. (wikipedia.org)
  • According to a study in the Journal of Alternative and Complementary Medicine, acupuncture, meditation, magnesium, l-carnitine and SAM-e (S-Adenosyl methionine), show the most promise in the treatment of chronic fatigue syndrome and fibromyalgia. (draxe.com)
  • Fatigue often lessens or stops when treatment ends, but sometimes it lingers. (nccn.org)
  • Tell your treatment team about your fatigue. (nccn.org)
  • Fatigue might get better after treatment ends for some, but last many months after treatment for others. (cancer.org)
  • Treatment of fatigue is generally directed toward the condition or disease that is causing the fatigue. (medicinenet.com)
  • Cancer and cancer treatment can change normal protein and hormone levels that are linked to inflammatory processes which can cause or worsen fatigue. (cancer.org)
  • If we can help the body be better modulated throughout treatment with the use of ginseng, we may be able to prevent severe long-term fatigue. (medicalnewstoday.com)
  • Fatigue usually improves after cancer treatment is finished, but some level of fatigue may continue for months or years. (cancer.ca)
  • Fatigue can be a short-term problem that goes away after treatment ends. (cancer.ca)
  • Follow-up after cancer treatment includes checking for fatigue. (cancer.ca)
  • And as of this month, when the FDA officially refused to approve Ampligen for treatment of chronic fatigue, she's not sure how much longer she'll be able to get the drug. (sfgate.com)
  • Our study indicates that behavioral interventions could be useful in the treatment of fatigue in diabetes, which we will determine in subsequent studies," Dr. Knoop told Medscape Medical News . (medscape.com)
  • Denton describes how he coped with fatigue (tiredness) during his treatment for prostate cancer. (macmillan.org.uk)
  • Fatigue is the most common side effect of breast cancer treatment. (breastcancer.org)
  • Some doctors estimate that 9 out of 10 people experience some fatigue during treatment. (breastcancer.org)
  • Fatigue from treatment can appear suddenly and can be overwhelming. (breastcancer.org)
  • As many as 800,000 Americans have chronic fatigue syndrome, which has no treatment or cure. (nytimes.com)
  • Unlike burnout, which is caused by everyday work stresses (dealing with insurance companies, making treatment choices), compassion fatigue results from taking on the emotional burden of a patient's agony. (dailystrength.org)
  • Cancer and cancer treatment may cause fatigue. (cancer.net)
  • And, some people may experience this kind of fatigue for months or years after finishing treatment. (cancer.net)
  • Managing symptoms, including fatigue, is an important part of your overall cancer care and treatment. (cancer.net)
  • In addition, your doctor should ask about your level of fatigue throughout treatment and recovery. (cancer.net)
  • Talk regularly with your doctor if you are experiencing fatigue during and after your cancer treatment. (cancer.net)
  • Is A Colon Cleanse An Effective Fatigue Treatment? (infobarrel.com)
  • For these people the entire treatment can take as much as six months to take full impact and free them of their fatigue symptoms. (infobarrel.com)
  • fatigue, in physiology, inability to perform reasonable and necessary physical or mental activity. (infoplease.com)
  • Fatigue is a general lack of alertness and degradation in mental and physical performance, and can affect pilot alertness, performance, and judgment during flight. (cdc.gov)
  • It may require much effort to get up and move around, but increasing your physical activity may reduce fatigue. (nccn.org)
  • the American criteria include a requirement for several physical symptoms, reflecting the belief that chronic fatigue syndrome has an underlying immunological or infective pathology. (bmj.com)
  • Sometimes fatigue is described as feeling a lack of energy and motivation (both mental and physical). (medicinenet.com)
  • But sometimes the distress becomes so great that it causes physical problems like fatigue. (cancer.org)
  • Fatigue can be described as the lack of energy and motivation (both physical and mental). (medicinenet.com)
  • Many illnesses can result in the complaint of fatigue and they can be physical, psychological, or a combination of the two. (medicinenet.com)
  • Physical fatigue , or muscle fatigue , is the temporary. (yahoo.com)
  • Fatigue, in medical terminology, refers to the state of reduced capacity for work or accomplishment following a period of mental or physical activity . (yahoo.com)
  • Both a physical exam and psychological evaluation may be needed to identify possible causes of fatigue and help find out what may be done to treat it. (cancer.ca)
  • Fatigue is the lack of mental or physical energy. (rxlist.com)
  • There was a high degree of internal consistency, and the principal components analysis supported the notion of a two-factor solution (physical and mental fatigue). (nih.gov)
  • Fatigue in MG is highly prevalent, mainly physical, and influenced by depressive symptoms, disease severity, female sex and sleep debt. (springer.com)
  • Significant predictors of chronic fatigue were younger age, clinically relevant depressive symptoms, more pain and sleeping problems, and a lower level of self-reported physical activity and self-efficacy concerning fatigue. (medscape.com)
  • Fatigue can result from both physical and emotional conditions. (healthy.net)
  • It is important to keep track of any other symptoms that take place with this fatigue, so both physical and emotional causes can be identified and dealt with. (healthy.net)
  • The onset of muscle fatigue during physical activity is gradual, and depends upon an individual's level of physical fitness - other factors include sleep deprivation and overall health. (wikipedia.org)
  • Physical fatigue can be caused by a lack of energy in the muscle, by a decrease of the efficiency of the neuromuscular junction or by a reduction of the drive originating from the central nervous system. (wikipedia.org)
  • Mental fatigue has also been shown to decrease physical performance. (wikipedia.org)
  • Did the fatigue come with the onset of menopause, follow menopause or could you be pregnant? (healthy.net)
  • The onset of mental fatigue during any cognitive activity is gradual, and depends upon an individual's cognitive ability, and also upon other factors, such as sleep deprivation and overall health. (wikipedia.org)
  • Retrieved on August 24, 2019 from https://www.news-medical.net/health/Chronic-Fatigue-Syndrome-Classification.aspx. (news-medical.net)
  • ASCO advises doctors to screen for and treat fatigue when they first diagnose cancer. (cancer.net)
  • Research indicates that exercise is one of the most effective ways to treat fatigue. (cancer.net)
  • What Causes Fatigue, and How Is It Treated? (thebody.com)
  • No one knows for sure what causes fatigue in early pregnancy, but it's possible that hormonal changes - like the dramatic rise in progesterone - are at least partly responsible. (babycenter.com)
  • What causes fatigue during pregnancy? (babycenter.com)
  • Unfortunately, healthcare providers do not know exactly what causes fatigue. (oncolink.org)
  • [4] This can lead to fatigue and temporary hearing loss if the outer hair cells do not get the opportunity to recover through periods of silence. (wikipedia.org)
  • These sleep changes can lead to fatigue. (cancer.org)
  • Neuromyelitis optica (NMO) doesn't cause fatigue, but living with the disease can lead to fatigue. (rxlist.com)
  • Vitamin D may also improve symptoms of fatigue. (healthline.com)
  • Those along with magnesium being low can have symptoms of fatigue and depressions, as well as other symptoms. (medhelp.org)
  • Symptoms of fatigue vary depending on their cause and other factors. (cancer.ca)
  • Feelings of inadequacy, low motivation and little desire for sex can also be symptoms of fatigue. (healthy.net)
  • These benefits have to be weighed against these symptoms [of fatigue and exercise intolerance]. (go.com)
  • Doctors first have to make sure that a person's fatigue and other symptoms are not caused by another illness, a sleep disorder, or hormone problems such as hypothyroidism. (kidshealth.org)
  • While the term "chronic fatigue" is fairly descriptive of this crippling illness, it doesn't tell the entire story. (draxe.com)
  • Chronic fatigue syndrome is hard to diagnose because a single diagnostic test does not exist and there is no identifiable cause of the illness. (kidshealth.org)
  • Chronic fatigue syndrome is most commonly triggered by an acute illness, like glandular fever, and it is the severity of this illness that decides whether you will develop the syndrome, the research found. (smh.com.au)
  • Chronic fatigue syndrome (CFS) is a long-term illness with a wide range of symptoms. (www.nhs.uk)
  • Chronic Fatigue Syndrome (CFS) is a poorly understood illness and there has been much debate surrounding the definition of the condition. (news-medical.net)
  • The illness is usually characterised as (profound) fatigue unrelieved by sleep that persists for more than six months (even small amounts of exercise are very tiring). (everything2.com)
  • citation needed] Temporary fatigue is likely to be a minor illness like the common cold as one part of the sickness behavior response that happens when the immune system fights an infection. (wikipedia.org)
  • Your doctor may prescribe medication based on the causes and severity of your fatigue. (nccn.org)
  • A self-rating scale was developed to measure the severity of fatigue. (nih.gov)
  • All subjects completed the fatigue subscale of the Checklist Individual Strength (CIS), an 8-item test that assesses fatigue severity over the past 2 weeks. (medscape.com)
  • Because there are so many causes of fatigue, there's no one medicine that can relieve fatigue. (breastcancer.org)
  • Your healthcare team may be able to help prevent or relieve fatigue and improve your quality of life. (macmillan.org.uk)
  • Complementary therapies such as massage, relaxation techniques, meditation, and yoga have been shown to help relieve fatigue. (oncolink.org)
  • Staying or becoming physically active can help relieve fatigue. (cancer.net)
  • Running head: COMPASSION FATIGUE: CARING FOR THE CAREGIVER Compassion Fatigue: Caring for the Caregiver Kimberly Flowers Grand Canyon University Spirituality in Health Care HLT-310V Patricia Mullen March 24, 2012 Compassion Fatigue: Caring for the Caregiver Introduction Compassion represents an "acknowledgement of another's suffering and is accompanied by the expression of a desire to ease or end that suffering. (bartleby.com)
  • The intent of the concept analysis on the subject of compassion fatigue is to evaluate compassion fatigue in nursing and to determine the current conceptual use in efforts to clarify the relevance to nurses. (bartleby.com)
  • practice (EBP) project was to educate ED nurses on compassion fatigue (CF) risk factors, causes, and symptoms as well as assist them in its identification among each other and within themselves. (bartleby.com)
  • Furthermore, this paper will discuss the scope of this problem such as the background and what the differences are in compassion fatigue and burnout and the purpose of why this research study is important in social work practice. (bartleby.com)
  • A Plan For Self-Care Against Compassion Fatigue Brian Murrison University of Kansas Introduction Working in the helping field has its many joys and privileges. (bartleby.com)
  • Some studies are beginning to suggest that animal care professionals may be number one in vulnerability to Compassion Fatigue and Burnout. (petfinder.com)
  • And they're a growing concern among physicians, who have a name for what's happening: compassion fatigue. (dailystrength.org)
  • About 6 to 8 percent of physicians and nurses suffer compassion fatigue," says Michael Kearney, MD, the lead author of a report on the subject published this year in the Journal of the American Medical Association. (dailystrength.org)
  • Philip Muskin, MD, a professor of clinical psychiatry at Columbia University Medical Center, has also gone through compassion fatigue. (dailystrength.org)
  • For the millions of ordinary people who become caregivers, Muskin says the most important way to prevent compassion fatigue is simply to recognize that it can occur. (dailystrength.org)
  • Research suggests that reflective writing helps prevent compassion fatigue. (dailystrength.org)
  • Incidence/prevalence Community and primary care based studies have reported the prevalence of chronic fatigue syndrome to be 0.2-2.6%, depending on the criteria used. (bmj.com)
  • World-renowned muscle fatigue researchers, Roger Enoka and Doug Stuart (1992), describe fatigue as an over-all concept intended to symbolize an acute impairment of performance that includes both an increase in perceived effort necessary to exert a desired force and an eventual inability to produce this force. (unm.edu)
  • Please describe your experience with fatigue. (medicinenet.com)
  • Through extensive experimental, theoretical, and computational investigations, we demonstrate a similarity between the indentation fatigue depth propagation and the fatigue crack growth, and propose an indentation fatigue depth propagation law and indentation fatigue strength law to describe indentation fatigue-induced deformation and failure of materials, respectively. (springer.com)
  • Apocalypse Fatigue" is a term I coined to describe a phenomena in mainstream comics , where com panies have ever escalating levels of destruction and cosmic catastrophe in their titles, in order to titillate readers who are immune to the normal progression of comic book plots. (everything2.com)
  • Fatigue is hard to describe. (breastcancer.org)
  • If you start to really feel sluggish and common fatigue has set in a good detoxifying can rid of the additional baggage and toxins which might be weighing you down. (infobarrel.com)
  • A person with fatigue feels extremely tired and weak. (medicalnewstoday.com)
  • The significant relationship of fatigue with cognitive-behavioral variables and weak association with blood glucose levels suggest that behavioral interventions might help chronic fatigue in type 1 diabetes, the authors write. (medscape.com)
  • When your blood sugar dips, you may feel fatigue. (healthline.com)
  • These can make you feel more fatigued as your blood sugar spikes. (healthline.com)
  • If you feel tired even after you rest, talk with your health care provider about fatigue. (thebody.com)
  • A person who is fatigued feels exhausted, however, does not necessarily feel like sleeping. (parkinson.org)
  • When fatigue is mixed with other symptoms, treating those symptoms may help people feel more energetic. (parkinson.org)
  • Fatigue may make it hard to start exercising, but it may make you feel more energetic afterward. (parkinson.org)
  • Little formal research has looked into a direct link between endometriosis and fatigue, but there are several reasons why endometriosis can make a person feel tired all the time. (medicalnewstoday.com)
  • What does fatigue feel like? (medicalnewstoday.com)
  • People with endometriosis may feel especially fatigued around the time of their menstrual cycle. (medicalnewstoday.com)
  • When fatigue is severe, a person will often take long naps and feel faint when rising or moving too quickly. (medicalnewstoday.com)
  • Q: What should I do if I feel some of the signs of vocal fatigue coming on? (uiowa.edu)
  • If you feel fatigue creeping in and your day of teaching is not yet complete, keep a stash of activities handy for students: ten minutes of quiet independent reading, group or partnered activities, work stations, or student recitations. (uiowa.edu)
  • If first trimester fatigue is getting you down, take heart that soon enough you'll be in your second trimester and probably feel much more energetic. (babycenter.com)
  • Did you start to feel fatigued after taking medicine? (healthy.net)
  • I finished the RX 3 days ago and still feel fatigued. (drugs.com)
  • People who undergo a colon cleansing generally feel the fatigue go away in the first week, however it might take a bit longer. (infobarrel.com)
  • Guilt, anxiety and anger are all common emotional responses for those fighting chronic fatigue. (draxe.com)
  • As a common phenomenon, static fatigue is manifested in many kinds of embrittlement , of which the mechanisms are closely related to the nucleation and growth of cracks . (wikipedia.org)
  • Chronic fatigue syndrome is more common in females than males and affects all racial and ethnic groups. (kidshealth.org)
  • Fatigue is common in people with cancer, but it's different for each person. (cancer.org)
  • Assistant professor of mechanical engineering and materials science Nitin Sharma of the University of Pittsburgh is part of a team working with robotic exoskeletons to assist with a common problem that hasn't received much attention: the fatigue experienced by users of traditional exoskeletons. (asme.org)
  • Fatigue is common early in the course of PD, but can occur at any point and can happen whether movement symptoms are mild or severe. (parkinson.org)
  • Chronic fatigue syndrome can affect people of all ethnicities and ages, but is most common in people in their forties or fifties. (kidshealth.org)
  • Yes, fatigue is especially common during the first trimester , and the condition tends to return in late pregnancy. (babycenter.com)
  • Living in today's hectic world, we are all overworked and overstressed and this is one of the most common causes of fatigue. (scientificamerican.com)
  • Chronic fatigue is a common problem among people with type 1 diabetes , a new observational Dutch study finds. (medscape.com)
  • Fatigue is one of the most common side effects reported by people receiving cancer treatments (surgery, chemotherapy, radiation therapy, or other drug therapy). (oncolink.org)
  • Fatigue is perhaps the most common thing a household physician might hear about. (infobarrel.com)
  • Incorporate exercise routines into your day to build stamina and reduce fatigue. (rxlist.com)
  • Some complementary and holistic medicine techniques can reduce fatigue, as can exercising more and a healthy diet. (breastcancer.org)
  • A well-balanced diet may help reduce fatigue. (cancer.net)
  • Fatigue at this level impacts your emotional and psychological well-being, too. (mayoclinic.org)
  • A NIST co-organized workshop identified the current needs for metal AM fatigue and fracture (F&F), which helped create the focus of this project. (nist.gov)
  • F&F properties of interest identified during the workshop include high-cycle fatigue (HCF), low-cycle fatigue (LCF), linear elastic fracture toughness (K Ic ), elastic-plastic fracture toughness (J-int), fatigue crack growth rate (FCGR), and impact toughness (Charpy). (nist.gov)
  • Scanning electron microscope (SEM) images of AM titanium alloy (Ti-6Al-4V) high-cycle fatigue fracture surfaces showing fatigue crack initiation at lack-of-fusion (LOF) defect (white arrow). (nist.gov)
  • ASTM's fatigue and fracture standards provide the appropriate procedures for carrying out fatigue, fracture, and other related tests on specified materials. (astm.org)
  • These fatigue and fracture standards are useful to manufacturers and other users concerned with such materials in understanding their failure and stability mechanisms. (astm.org)
  • Fatigue is tiredness that does not go away when you rest. (thebody.com)
  • This could be fatigue ― a feeling of deep tiredness that does not improve with rest. (parkinson.org)
  • Symptoms of CFS often develop suddenly and include a strong, noticeable fatigue that comes and goes or remains for months. (kidshealth.org)
  • Existing fatigue measures include Multidimensional Fatigue Inventory (MFI) and the Multidimensional Assessment of Fatigue (MAF). (news-medical.net)
  • Some of the article topics include: Are There Any Chronic Fatigue Treatments? (tradebit.com)
  • Some of the article topics include: Effective Ways to Treat Adrenal Fatigue Fatigue: Restore Y. (tradebit.com)
  • But CFS is different from normal feelings of fatigue and low energy. (kidshealth.org)
  • [5] The benefits of exercise are especially great for people with no established exercise routine, so if you're not physically active, try working out regularly to fight your feelings of fatigue. (wikihow.com)
  • as that burden is eased, it should balance out any feelings of frugal fatigue. (marketwatch.com)
  • Though these tips are no cure for crisis fatigue, they may provide a slight relief from your negative feelings. (unh.edu)
  • Fatigue and 'feelings of fatigue' are sometimes confused. (wikipedia.org)
  • If you think you may be experiencing crisis fatigue, or know someone who is, check out these tips to help cope in healthier ways. (unh.edu)
  • How can I cope with fatigue during pregnancy? (babycenter.com)
  • Lifestyle changes and help from your cancer care team may help you cope with fatigue. (cancer.net)
  • In muscle tissue, the depletion of glycogen (stored glucose), a source of energy for muscle cells, and the accumulation of lactic acid , which is produced through the breakdown of glucose, was long thought to the cause of muscle fatigue, but it is now known that the lactic acid produced is used as an energy source as well. (infoplease.com)
  • A new explanation of muscle fatigue suggests that it is related to the control of the flow of the calcium ions in muscle. (infoplease.com)
  • Physiological processes that contribute to fatigue are grouped into two categories: 1) Central, which is muscle activation signaling from the brain, and 2) Peripheral, which are the physiological mechanisms occurring at the neuromuscular junction and within the contracting muscle. (unm.edu)
  • What is Causing the Fatigue in Muscle? (unm.edu)
  • Reid continues that the large body of research now conclusively agrees that these generated ROS clearly impact the loss of muscle function occurring during fatigue. (unm.edu)
  • Hunter summarizes that women are less fatigable then men during isometric fatiguing tasks for several muscle groups. (unm.edu)
  • It is interesting to note that the sex fatigue differences actually vary between muscle groups. (unm.edu)
  • In addition, Hunter notes that sex fatigue differences are less for high-intensity isometric contractions as compared to low-intensity isometric muscle contractions. (unm.edu)
  • In regards to dynamic muscle functions, the emerging evidence indicates that sex differences in fatigue are task specific (Hunter). (unm.edu)
  • The main area of muscle fatigue difference in men and women is in the contractile mechanisms of muscle (Hunter, 2016). (unm.edu)
  • This is where you get information when it comes to muscle mass fatigue. (asme.org)
  • They were using ultrasound and correlating ultrasound signals with muscle fatigue. (asme.org)
  • Much like muscle fatigue, if you flex your 'decision' muscle too much, it will fail you. (lifehacker.com)
  • The subjective feeling of fatigue in myasthenia gravis (MG) is poorly elucidated, in part because it is often confounded with the objective sign of muscle fatigability. (springer.com)
  • The work-outs I've seen state to lift until muscle fatigue/failure. (exrx.net)
  • Eating well, sleeping for more than 6 hours in a day, and keeping physically active may play a major role in counteracting fatigue. (amazonaws.com)
  • If known, what was the cause of your fatigue? (medicinenet.com)
  • Work with your health care provider to find the cause of your fatigue and the best way to treat it. (thebody.com)
  • [1] [2] When it comes to curing fatigue, there's no substitute for consistently getting a good night's sleep, so if you don't know the cause of your fatigue, start here. (wikihow.com)
  • Once your healthcare team knows the cause of your fatigue, they can suggest ways to treat it. (cancer.ca)
  • People with CFS have debilitating fatigue that lasts for six months or longer. (encyclopedia.com)
  • The fatigue lasts for six months or more. (healthy.net)
  • However, some professionals believe it is closely related to adrenal fatigue or system wide inflammation of the body. (draxe.com)
  • Adrenal Fatigue - 25 Plr Articles Pack! (tradebit.com)
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  • Exercise may also help you manage your fatigue. (healthline.com)
  • Indeed, the physiology of fatigue has been of great interest to researchers for many decades and was recently a special section of articles in the journal, Medicine & Science in Sports & Exercise. (unm.edu)
  • In order to address some of the diverse topics on fatigue, this column will approach these issues with a 'Question and Answer' format to specifically address relevant issues of exercise fatigue. (unm.edu)
  • More research in this area will eventually elucidate new and difference recovery strategies for men and women after fatiguing endurance exercise (Hunter). (unm.edu)
  • Regular moderate exercise - especially walking - is a good way to ease fatigue. (cancer.org)
  • And not only can exercise help fatigue, it can help you sleep better, too. (cancer.org)
  • New research suggests regular exercise can increase energy levels even among people suffering from chronic medical conditions associated with fatigue , like cancer and heart disease . (webmd.com)
  • A lot of times when people are fatigued, the last thing they want to do is exercise," says researcher Patrick O'Connor, PhD, in a news release. (webmd.com)
  • But if you're physically inactive and fatigued, being just a bit more active will help," says O'Connor, co-director of the University of Georgia exercise psychology laboratory, in Athens, Ga. (webmd.com)
  • In this study, published in Psychological Bulletin, the researchers analyzed 70 studies on exercise and fatigue involving more than 6,800 people. (webmd.com)
  • More than 90% of the studies showed the same thing: Sedentary people who completed a regular exercise program reported improved fatigue compared to groups that did not exercise," says O'Connor. (webmd.com)
  • The results show that regular exercise increases energy and reduces fatigue. (webmd.com)
  • Research has shown that even minor increases in the amount of exercise a person participates in can have a major effect on the level of fatigue she feels. (wikihow.com)
  • Light exercise also helps fight fatigue like walking in open air. (medhelp.org)
  • Although counterintuitive to many, it's essential for keeping fatigue from worsening that a minimum of 15 minutes each day are used for stretching, yoga, tai chi or another gentle movement exercise. (drugs.com)
  • statin users were significantly more fatigued, and more intolerant to exercise. (go.com)
  • And now fatigue and exercise intolerance may be added to the list of side effects. (go.com)
  • Exercise has consistently been shown to improve fatigue levels and quality of life. (oncolink.org)
  • This temporary, short-term, or long-term fatigue must be distinguished from CFS. (labtestsonline.org)
  • Anyone struggling with long term fatigue should see their doctor to see if any of those are the explanations for his or her condition. (infobarrel.com)
  • Long-term fatigue is defined as full recovery from temporary threshold shifts taking at least several minutes to occur. (wikipedia.org)
  • Threshold shifts that result in long-term fatigue are dependent on level of sound and length of exposure. (wikipedia.org)
  • While that's still not good, there's a notion in the community that people with chronic fatigue never get better,' he said. (smh.com.au)
  • The discovery of mouse virus fragments in cells from people with chronic fatigue syndrome has reinforced earlier claims that they may cause the condition. (newscientist.com)
  • Instead, Shyh-Ching Lo of the Food and Drug Administration in Bethesda, Maryland, and colleagues found that blood samples from 32 of 37 people with chronic fatigue syndrome contained "polytropic" murine leukaemia virus-related fragments, compared with only three of 44 healthy blood donors. (newscientist.com)
  • That's why the rejection of Ampligen was especially upsetting to so many chronic fatigue sufferers, said Dr. Jose Montoya , an infectious disease specialist who helped establish a chronic fatigue syndrome team at Stanford. (sfgate.com)
  • And now for my question im sure all us fatigue sufferers are all wondering. (thebody.com)
  • Fatigue is one of two main ways the body warns you about a problem. (thebody.com)
  • My main concern is the fatigue. (drugs.com)