False Positive Reactions
Treponema Immobilization Test
Latex Fixation Tests
Patch Tests
False Negative Reactions
Sensitivity and Specificity
Skin Tests
Cross Reactions
Complement Fixation Tests
Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.
Enzyme-Linked Immunosorbent Assay
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Immunoenzyme Techniques
Agglutination Tests
Evaluation Studies as Topic
Algorithms
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Immunohistochemistry
Fluorescent Antibody Technique
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
Histocytochemistry
Sparganum
Antigens, Helminth
Hemagglutination Tests
Dermatitis, Occupational
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Reagent Kits, Diagnostic
Immune Sera
Dermatitis, Photoallergic
A delayed hypersensitivity involving the reaction between sunlight or other radiant energy source and a chemical substance to which the individual has been previously exposed and sensitized. It manifests as a papulovesicular, eczematous, or exudative dermatitis occurring chiefly on the light-exposed areas of the skin.
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Drug Monitoring
Tuberculin
Tuberculin Test
Universal Precautions
BCG Vaccine
Practice Guidelines as Topic
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Tuberculosis
Clonazepam
An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
Disulfiram
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Carbamazepine
Diphenhydramine
Citrus paradisi
Echinococcosis
Echinococcosis, Hepatic
Liver disease caused by infections with parasitic tapeworms of the genus ECHINOCOCCUS, such as Echinococcus granulosus or Echinococcus multilocularis. Ingested Echinococcus ova burrow into the intestinal mucosa. The larval migration to the liver via the PORTAL VEIN leads to watery vesicles (HYDATID CYST).
Echinococcus
Echinococcosis, Pulmonary
Rational sequence of tests for pancreatic function. (1/3575)
Of 144 patients with suspected pancreatic disease in whom a 75Se-selenomethionine scan was performed, endoscopic retrograde pancreatography (ERP) was successful in 108 (75%). The final diagnosis is known in 100 patients and has been compared with scan and ERP findings. A normal scan reliably indicated a normal pancreas, but the scan was falsely abnormal in 30%. ERP distinguished between carcinoma and chronic pancreatitis in 84% of cases but was falsely normal in five patients with pancreatic disease. In extrahepatic biliary disease both tests tended to give falsely abnormal results. A sequence of tests to provide a rapid and reliable assessment of pancreatic function should be a radio-isotope scan, followed by ERP if the results of the scan are abnormal, and a Lundh test if the scan is abnormal but the findings on ERP are normal. (+info)Defining and analysing symptom palliation in cancer clinical trials: a deceptively difficult exercise. (2/3575)
The assessment of symptom palliation is an essential component of many treatment comparisons in clinical trials, yet an extensive literature search revealed no consensus as to its precise definition, which could embrace relief of symptoms, time to their onset, duration, degree, as well as symptom control and prevention. In an attempt to assess the importance of these aspects and to compare different methods of analysis, we used one symptom (cough) from a patient self-assessment questionnaire (the Rotterdam Symptom Checklist) in a large (>300 patient) multicentre randomized clinical trial (conducted by the Medical Research Council Lung Cancer Working Party) of palliative chemotherapy in small-cell lung cancer. The regimens compared were a two-drug regimen (2D) and a four-drug regimen (4D). No differences were seen between the regimens in time of onset of palliation or its duration. The degree of palliation was strongly related to the initial severity: 90% of the patients with moderate or severe cough at baseline reported improvement, compared with only 53% of those with mild cough. Analyses using different landmark time points gave conflicting results: the 4D regimen was superior at 1 month and at 3 months, whereas at 2 months the 2D regimen appeared superior. When improvement at any time up to 3 months was considered, the 4D regimen showed a significant benefit (4D 79%, 2D 60%, P = 0.02). These findings emphasize the need for caution in interpreting results, and the importance of working towards a standard definition of symptom palliation. The current lack of specified criteria makes analysis and interpretation of trial results difficult, and comparison across trials impossible. A standard definition of palliation for use in the analysis of clinical trials data is proposed, which takes into account aspects of onset, duration and degree of palliation, and symptom improvement, control and prevention. (+info)Computerized analysis of abnormal asymmetry in digital chest radiographs: evaluation of potential utility. (3/3575)
The purpose of this study was to develop and test a computerized method for the fully automated analysis of abnormal asymmetry in digital posteroanterior (PA) chest radiographs. An automated lung segmentation method was used to identify the aerated lung regions in 600 chest radiographs. Minimal a priori lung morphology information was required for this gray-level thresholding-based segmentation. Consequently, segmentation was applicable to grossly abnormal cases. The relative areas of segmented right and left lung regions in each image were compared with the corresponding area distributions of normal images to determine the presence of abnormal asymmetry. Computerized diagnoses were compared with image ratings assigned by a radiologist. The ability of the automated method to distinguish normal from asymmetrically abnormal cases was evaluated by using receiver operating characteristic (ROC) analysis, which yielded an area under the ROC curve of 0.84. This automated method demonstrated promising performance in its ability to detect abnormal asymmetry in PA chest images. We believe this method could play a role in a picture archiving and communications (PACS) environment to immediately identify abnormal cases and to function as one component of a multifaceted computer-aided diagnostic scheme. (+info)Brightness alters Heidelberg retinal flowmeter measurements in an in vitro model. (4/3575)
PURPOSE: The Heidelberg Retinal Flowmeter (HRF), a laser Doppler flowmetry device, has captured interest as a research and clinical tool for measurement of ocular blood flow. Concerns remain about the range and accuracy of the values that it reports. METHODS: An in vitro blood-flow model was constructed to provide well-controlled laminar flow through a glass capillary for assessment by HRF. A change in material behind the glass capillary was used to simulate changing brightness conditions between eyes. RESULTS: Velocities reported by the HRF correlated linearly to true velocities below 8.8 mm/sec. Beyond 8.8 mm/sec, HRF readings fluctuated randomly. True velocity and HRF reported velocities were highly correlated, with r = 0.967 (P < 0.001) from 0.0 mm/sec to 2.7 mm/sec mean velocity using a light background, and r = 0.900 (P < 0.001) from 2.7 mm/sec to 8.8 mm/sec using a darker background. However, a large change in the y-intercept occurred in the calibration curve with the background change. CONCLUSIONS: The HRF may report velocities inaccurately because of varying brightness in the fundus. In the present experiment, a darker background produced an overreporting of velocities. An offset, possibly introduced by a noise correction routine, apparently contributed to the inaccuracies of the HRF measurements. Such offsets vary with local and global brightness. Therefore, HRF measurements may be error prone when comparing eyes. When used to track perfusion in a single eye over time, meaningful comparison may be possible if meticulous care is taken to align vessels and intensity controls to achieve a similar level of noise correction between measurements. (+info)Improved methods using the reverse transcriptase polymerase chain reaction to detect tumour cells. (5/3575)
Reverse transcriptase polymerase chain reaction (RT-PCR) is increasingly used to detect small numbers of circulating tumour cells, though the clinical benefit remains controversial. The largest single contributing factor to the controversy of its value is the different approaches to sample processing. The aim of this study was to compare the sensitivity and reproducibility of RT-PCR for the detection of tumour cells after four commonly used different methods of sample processing. Using RT-PCR, one tumour cell spiked in 2 ml of whole blood was detected after analysis of separated mononuclear cell RNA, whole blood total or poly-A+ RNA. No false positives were identified with any method. However, the reproducibility of tumour cell detection was reduced after isolation of the mononuclear cell fraction. Only analysis of poly-A+ RNA had a sensitivity of 100% in all the cell spiking experiments. In patient blood samples, analysis of poly-A+ RNA increased the number of blood samples positive for tyrosine hydroxylase (TH) mRNA compared with those positive after analysis of total RNA. This may reflect high levels of cDNA reducing the efficiency of the PCR. Isolation of poly-A+ RNA increases the sensitivity and reproducibility of tumour cell detection in peripheral blood. (+info)Extensive cross-contamination of specimens with Mycobacterium tuberculosis in a reference laboratory. (6/3575)
A striking increase in the numbers of cultures positive for Mycobacterium tuberculosis was noticed in a mycobacterial reference laboratory in Campinas, Sao Paulo State, Brazil, in May 1995. A contaminated bronchoscope was the suspected cause of the increase. All 91 M. tuberculosis isolates grown from samples from patients between 8 May and 18 July 1995 were characterized by spoligotyping and IS6110 fingerprinting. Sixty-one of the 91 isolates had identical spoligotype patterns, and the pattern was arbitrarily designated S36. The 61 specimens containing these isolates had been processed and cultured in a 21-day period ending on 1 June 1995, but only 1 sample was smear positive for acid-fast bacilli. The patient from whom this sample was obtained was considered to be the index case patient and had a 4+ smear-positive lymph node aspirate that had been sent to the laboratory on 10 May. Virtually all organisms with spoligotype S36 had the same IS6110 fingerprint pattern. Extensive review of the patients' charts and investigation of laboratory procedures revealed that cross-contamination of specimens had occurred. Because the same strain was grown from all types of specimens, the bronchoscope was ruled out as the outbreak source. The most likely source of contamination was a multiple-use reagent used for specimen processing. The organism was cultured from two of the solutions 3 weeks after mock contamination. This investigation strongly supports the idea that M. tuberculosis grown from smear-negative specimens should be analyzed by rapid and reliable strain differentiation techniques, such as spoligotyping, to help rule out laboratory contamination. (+info)Introduction of appendiceal CT: impact on negative appendectomy and appendiceal perforation rates. (7/3575)
OBJECTIVE To evaluate the impact of appendiceal computed tomography (CT) availability on negative appendectomy and appendiceal perforation rates. SUMMARY BACKGROUND DATA: Appendiceal CT is 98% accurate. However, its impact on negative appendectomy and appendiceal perforation rates has not been reported. METHODS: The authors reviewed the medical records of 493 consecutive patients who underwent appendectomy between 1992 and 1995, 209 consecutive patients who underwent appendectomy in 1997 (59% of whom had appendiceal CT), and 206 patients who underwent appendiceal CT in 1997 without subsequent appendectomy. RESULTS: Before appendiceal CT, 98/493 patients (20%) taken to surgery had a normal appendix. After CT availability, 15/209 patients (7%) taken to surgery had a normal appendix; 7 patients did not have CT, 5 patients had surgery despite a negative CT, and 3 patients had a false-positive CT. Negative appendectomy rates were lowered overall (20% to 7%), in men (11% to 5%), in women (35% to 11%), in boys (10% to 5%), and in girls (18% to 12%). Appendiceal perforation rates dropped from 22% to 14% after CT availability. CT excluded appendicitis in 206 patients in 1997 who avoided appendectomy and identified alternative diagnoses in 105 of these patients (51%). CONCLUSION: The availability of appendiceal CT coincided with a drop in the negative appendectomy rate from 20% to 7% in all patients, and to only 3% in patients with a positive CT. Perforation rates decreased from 22% to 14%. Appendiceal CT can be advocated in nearly all female and many male patients. (+info)Comparison of standard and CA-125 response criteria in patients with epithelial ovarian cancer treated with platinum or paclitaxel. (8/3575)
PURPOSE: To assess CA-125 as a measure of response in patients treated with paclitaxel. PATIENTS AND METHODS: One hundred forty-four patients treated with paclitaxel derived from four different trials and 625 patients treated with platinum from two trials were analyzed using precisely defined 50% and 75% reductions in CA-125. The standard and CA-125 response rates to paclitaxel and platinum were compared. In addition, we analyzed individual patient groups in which there was a difference in response according to the two response criteria. RESULTS: Patients with stable disease as determined by standard criteria who were treated with platinum and responded according to CA-125 criteria have an improved median progression-free survival compared with patients with stable disease who did not respond according to CA-125 criteria (10.6 v 4.8 months; P<.001). Standard and CA-125 response rates for patients treated with platinum (58.93% v 61.31%, respectively) and paclitaxel (30.65% v 31.67%, respectively) were very similar, as were rates of false-positive prediction of response by CA-125 (platinum 2.2% and paclitaxel 2.9%). Responders to paclitaxel had a significantly improved progression-free survival compared with non-responders by both standard criteria (median progression-free survival, 6.8 v 2.5 months; P<.001) and CA-125 criteria (median progression-free survival, 6.8 v 3.4 months; P<.001). CONCLUSION: Forassessing activity of therapy for ovarian cancer, these data show that precise 50% or 75% CA-125 response criteria are as sensitive as standard response criteria. We propose that they may be used as a measure of response in lieu of or in addition to standard response criteria in clinical trials involving epithelial ovarian cancer. Sensitivity is maintained whether patients are treated with platinum or paclitaxel. (+info)
Tips From Other Journals - American Family Physician
Review of False-Positive Cultures for Mycobacterium tuberculosis and Recommendations for Avoiding Unnecessary Treatment :...
HIV vaccines may induce HIV antibodies in trial participants, can cause false-positive test result
Menopause Temperature Hot Flash Metformin Can False Positive Test Pregnancy Cause - Menopause Villa-Agata
surgery Archives - TopHealthNews.net
Which Factors Contribute to False-Positive, False-Negative, and Invalid Results in Fetal Fibronectin Testing in Women with...
Patients & healthcare professionals values regarding true- & false-positive diagnosis when colorectal cancer screening by CT...
False Positives: What Over The Counter Drugs Can Set Off A False Positive Result? - The Drug Test News
Australia ends local COVID vaccine trials due to HIV false positives ⋆ The Savage Nation
Journal of Pediatrics Review - Zika Virus, Congenital Infection, and Neurologic Manifestations in Children: A Narrative Review
False positive results
How common is it for Hep B test to show false positive results?
Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial - Full Text View - ClinicalTrials.gov
British man recovered from HIV | MetaFilter
Hospital slashes false-positive diagnoses with CDS platform | Healthcare IT News
Library | North Star Vet Clinic British Columbia
More on universalversusselected screening for thrombophilia: the hidden costs of false-positive diagnosis - Favaloro - 2006...
Guide to the Application of Genotyping to Tuberculosis Prevention and Control | False-Positive Cultures | TB | CDC
Most recent papers with the keyword All on 4 | Read by QxMD
Adding 3D Tomography to Mammography Aids in Cancer Detection, Reduces False-Positives - ZPRad
mTOR - NF-κB signaling in inflammation and cancer
FDA Alert: Potential For False Positive Result With Antigen Tests For Rapid Detection of SARS-CoV-2
HIV or not? - Forum on Safe Sex and HIV Prevention -- TheBody.com
Epidemiology, Public Health, and the Rhetoric of False Positives
Detecting false positive sequence homology - a machine learning approach | RNA-Seq Blog
A Gentle Introduction to Threshold-Moving for Imbalanced Classification
False-Positive Mammogram Results May Turn Out Not to Be: Study - Drugs.com MedNews
Feedback on False Positives from Drug Testing, page 89
Feedback on False Positives from Drug Testing, page 72 - AskDocWeb.com
Reflectance confocal microscopy for diagnosising keratinocyte skin cancers in adults - Nottingham ePrints
What to Do If You Get False Positive for Amphetamines | New Health Advisor
Potential Hazards of Modern Whooping Cough Tests; False positive results, unnecessary antibiotics, and inaccurate statistics,...
Melanoma Archives - Dr. Michael Ruscio
Top Five Examples of Overdiagnosis and Unnecessary Treatment | Public Citizen
What is the cancer marker lab test cea something - Answers on HealthTap
PlantCazyme
MySQL Lists: commits: RE: WL#4222 Test patch review
Unnecessary treatment, medical services abound for minorities, Health Affairs study says | Healthcare Finance News
DLP: Education and/or Automation? - Anton Chuvakin
A false positive mammogram is a real risk factor for breast canc - NBC-2.com WBBH News for Fort Myers, Cape Coral & Naples,...
Molecular Diagnostics - Covaris
MedMemoWeb
MedMemoWeb: Prevention Archives
Is it possible to get a false positive | Ask The Doctor
Heart Tests Before Surgery: When you need an imaging test and when you dont - Choosing Wisely Canada
Positive Strep while on antibiotics - PANS / PANDAS (Lyme included) - ACN Latitudes Forums
Blood test ordering for unexplained complaints in general practice: the VAMPIRE randomised clinical trial protocol. ...
Multiplex cytokine analyses in patients with rheumatoid arthritis require use of agents blocking heterophilic antibody activity
Health News Report: December 2010
Journal of Clinical and Preventive Cardiology : Table of Contents
Laboratory blood, urine tests and liver biopsy used for the diagnosis of Wilsons disease in children and adults | Cochrane
Lyme Disease Overdiagnosis in a Large Healthcare System: A Population-based, Retrospective Study. - LymeNet Europe
Use of a Disposable Water Filter for Prevention of False-Positive Results due to Nontuberculosis Mycobacteria in a Clinical...
Carolines Breast Cancer Blog: False positive test results
Search Results
Overdiagnosis of COPD in subjects with unobstructed spirometry: a BOLD analysis - Nuffield Department of Population Health
Other Singapore labs not using same COVID-19 test kit, instrument that led to 33 false positive cases: MOH - CNA
Adding Ultrasonography to Mammography Increases False-Positive Findings Without an Increase in Cancer Detection
...
Chris Weekes - Speck Lab / DNA Replication Group - Christian Speck
High proportion of women experience anxiety following false-positive screening mammography - ONA
FDA - Potential for False Results with Roche Molecular Systems, Inc. cobas SARS-CoV-2 & Influenza Test for use on cobas Liat...
The Ministry of Health Advises Against Independent HIV Tests | Israel Foreign Affairs
The Chronicle of the Horse
Center for Public Health and Zoonoses Symposium 2019 - Rachel Finer | Summer CORE Program
False-positive results with select HIV-1 NAT methods following lentivirus-based tisagenlecleucel therapy<...
Validation of Hospital Administrative Dataset for adverse event screening | BMJ Quality & Safety
Glossaire
Example 54.5 Stratified Sampling :: SAS/STAT(R) 12.3 Users Guide
Diagnosis - Conditionpedia
Methodological issues in the study of violence against women | Journal of Epidemiology & Community Health
Corporate Medical Center Pushes Unnecessary Treatments
A cross-sectional study of blood cultures and antibiotic use in patients admitted from the Emergency Department: missed...
False-Positive Mammogram Results May Be Linked to Higher Risk Later in Life
A new criterion for detection of radiculopathy based on motor evoked potentials and intraoperative nerve root monitoring.
Healthcare, etc.: PSA screening: Does it or doesnt it?
Latest News in Allergy Testing: False Positives?
Consequences of false-positive screening mammograms<...
Final Report: Chapter 30 - Screening of Donated Blood for HIV
classification - What do the thresholds on x and y axis of ROC curve represent? - Cross Validated
Cross-Enterprise Document Sharing - IHE Wiki
RAD.00037 Whole Body Computed Tomography Scanning
The accuracy of mammographic interpretation
Pandemic Lab Meetings 03.2020 - Speck Lab / DNA Replication Group - Christian Speck
OP37 Psychological Consequences of False-Positive Screening Mammograms in the UK: A Systematic Review | Journal of Epidemiology...
Plus it
Do Mammograms really work? The Science! | EMFScience.com - EMF Detectors | EMF News | What is EMF?
David Yankelevitz, MD, Responds to Overdiagnosis Claims | I-ELCAP
Marker-assisted selection - Wikipedia
Plus it
Sandwhich ELISA using pig serum - ELISA
High quality urine test strips result in leukocytes Product Features
Biological false-positive tests comprise a high proportion of Venereal Disease Research Laboratory reactions in an analysis of...
Biological false-positive tests comprise a high proportion of Venereal Disease Research Laboratory reactions in an analysis of ... were biological false positive. BFP reactivity was found in 0.24% of all patients and was significantly higher in women than in ... a phenomenon referred to as biological false-positive (BFP) VDRL test. The aim of this study was to determine the frequency of ... 2 dilutions without a positive treponemal test was not reported. The subgroup of HIV-positive patients (n = 1415) revealed a 10 ...
Reactions to 'false-positive' prostate cancer screening...( Men who get a false-positive prostat...)
Reactions,to,false-positive,prostate,cancer,screenings,assessed,medicine,medical news today,latest medical news,medical ... Men who get a false-positive prostate cancer result -- an abnormal s...The study findings based on telephone surveys of 210 men ... Men with false-positives were about three times as likely to report being at least somewhat worried about getting prostate ... Men who get a "false-positive" prostate cancer result -- an abnormal screening test followed by a biopsy indicating no evidence ...
False positive reactions for IgA and IgG anti-tissue transglutaminase antibodies in liver cirrhosis are common and method...
... and the positives found are generally false positives, partly due to the high immunoglobulin concentration. ... False positive reactions for IgA and IgG anti-tissue transglutaminase antibodies in liver cirrhosis are common and method- ... and the positives found are generally false positives, partly due to the high immunoglobulin concentration. ... The largest number of false positives was found with methods that used tTG in association with gliadin peptides as antigen ...
false-positive reaction | Taber's Medical Dictionary
false-positive reaction answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, ... reaction. Accessed July 6, 2020.. False-positive reaction. (2017). In Venes, D. (Ed.), Tabers Medical Dictionary (23rd edition ... reaction. False-positive Reaction [Internet]. In: Venes D, editors. Tabers Medical Dictionary. F.A. Davis Company; 2017. [ ... false-positive reaction is a topic covered in the Tabers Medical Dictionary. To view the entire topic, please sign in or ...
ON THE IMPORTANCE OF MALARIA AS A CAUSE OF FALSE POSITIVE SEROLOGIC REACTIONS* | Annals of Internal Medicine | American College...
FALSE-POSITIVE REACTION TO THE REGITINE TEST FOR PHEOCHROMOCYTOMA: REPORT OF A CASE1 Annals of Internal Medicine; 41 (5): 1061- ... ON THE IMPORTANCE OF MALARIA AS A CAUSE OF FALSE POSITIVE SEROLOGIC REACTIONS1. Ann Intern Med. ;19:651-655. doi: 10.7326/0003- ... ON THE IMPORTANCE OF MALARIA AS A CAUSE OF FALSE POSITIVE SEROLOGIC REACTIONS1 T. R. DAWBER, M.D. ... THE INCIDENCE AND ETIOLOGIC BACKGROUND OF CHRONIC BIOLOGIC FALSE-POSITIVE REACTIONS IN SEROLOGIC TESTS FOR SYPHILIS: ...
False positive reaction of Kasperskiy to early app version
Chronic biological false-positive reactions to serological tests for syphilis in blood donors | Journal of Clinical Pathology
... showed biological false-positive reactions.. There were 80 sera from blood donors which gave biological false-positive ... Sixty-six of the sera showed chronic biological false-positive reactions. Some donors were only found reactive for the first ... Chronic biological false-positive reactions to serological tests for syphilis in blood donors ... Chronic biological false-positive reactions to serological tests for syphilis in blood donors ...
Prevalence and clinical characteristics of patients with biologically false-positive reactions with serological syphilis...
Objectives Biologically false positive (BFP) reactions are well described in early literature. However, only a few recent ... Prevalence and clinical characteristics of patients with biologically false-positive reactions with serological syphilis ... Prevalence and clinical characteristics of patients with biologically false-positive reactions with serological syphilis ... Conclusion There was a low incidence of BFP reactions in the last decade. A minority of BFP reactions had high non-treponemal ...
False Positive Reactions | Colorado PROFILES
"False Positive Reactions" by people in this website by year, and whether "False Positive Reactions" was a major or minor topic ... "False Positive Reactions" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... False Positive Reactions*False Positive Reactions. *False Positive Reaction. *Positive Reaction, False ... Below are the most recent publications written about "False Positive Reactions" by people in Profiles. ...
'More positive about mammography' - reactions of women to a false positive recall: a qualitative study of women at risk of...
More positive about mammography - reactions of women to a false positive recall: a qualitative study of women at risk of ... and sought to understand the reactions of women who had received an initial all-clear result and who had received an all-clear ... women who were recalled for further tests prior to an all-clear result reported significantly more positive feelings post ... ability of mammography to detect a cancer at an early stage gave reassurance that a cancer diagnosis could lead to a positive ...
False Positive Reactions | ISHAR Online
... are likely to generate false positive results. Based on electronic searches in six databases, 13 studies were found that met ... are likely to generate false positive results. Based on electronic searches in six databases, 13 studies were found that met ... design is prone to false positive results and discuss the design features that might prevent or exacerbate this problem. ... design is prone to false positive results and discuss the design features that might prevent or exacerbate this problem. ...
Tubersol Dosage Guide - Drugs.com
False Positive Reactions. False positive tuberculin reactions can occur in individuals who have been infected with other ... Negative Reactions. An individual who does not show a positive reaction to 5 TU on the first test, but is suspected of being TB ... False-Negative Reactions. Not all infected persons will have a delayed hypersensitivity reaction to a tuberculin test. ... Persons showing positive tuberculin reactions should be considered positive by current public health guidelines and referred ...
False-positive reactions with enzyme-linked immunosorbent assay of Mycobacterium tuberculosis antigens in pleural fluid |...
False-positive reactions in patients with lung cancer limit the usefulness of ELISA with conventional anti-BCG antibody for ... False-positive reactions with enzyme-linked immunosorbent assay of Mycobacterium tuberculosis antigens in pleural fluid * R. ... False-positive reactions in patients with lung cancer limit the usefulness of ELISA with conventional anti-BCG antibody for ... Detection of a wide range of medically important fungi by the polymerase chain reaction K. Makimura, Somay Y. Murayama and H. ...
DailyMed - TUBERSOL- tuberculin purified protein derivative injection, solution
False Positive Reactions. False positive tuberculin reactions can occur in individuals who have been infected with other ... False positive or false negative tuberculin skin test reactions may occur in some individuals. (See Interpretation of the Test ... False positive tuberculin reaction tests occur in individuals who have been infected with other mycobacteria, including ... Negative Reactions. An individual who does not show a positive reaction to 5 TU on the first test, but is suspected of being TB ...
Elimination of false-positive polymerase chain reaction results resulting from hole punch carryover contamination - Murdoch...
Elimination of false-positive polymerase chain reaction results resulting from hole punch carryover contamination ... 2008) Elimination of false-positive polymerase chain reaction results resulting from hole punch carryover contamination. ... It was determined that false-positive results could be obtained at least 13 times after a positive sample. Subsequently, the ... causing false-positive results by PCR. In the present study, filter-paper-collected blood that contained beak and feather ...
Association of Biologic False-Positive Reactions for Syphilis with Human Immunodeficiency Virus Infection<...
Association of Biologic False-Positive Reactions for Syphilis with Human Immunodeficiency Virus Infection. / Rompalo, Anne M.; ... Rompalo, A. M., Cannon, R. O., Quinn, T. C., & Hook, E. W. (1992). Association of Biologic False-Positive Reactions for ... Rompalo, Anne M. ; Cannon, Robert O. ; Quinn, Thomas C. ; Hook, Edward W. / Association of Biologic False-Positive Reactions ... Rompalo, AM, Cannon, RO, Quinn, TC & Hook, EW 1992, Association of Biologic False-Positive Reactions for Syphilis with Human ...
Benadryl 10 month old runny nose can u take tramadol if pregnant clindamycin hcl reactions oxcarbazepine false positive
RNA Therapeutics - & related info | Mendeley
Coproantigen detection for immunodiagnosis of echinococcosis and taeniasis in dogs and humans
Brucella melitensis B115-Based ELISA to Unravel False Positive Serologic Reactions in Bovine Brucellosis: A Field Study |...
Brucella melitensis B115-Based ELISA to Unravel False Positive Serologic Reactions in Bovine Brucellosis: A Field Study ... Brucella melitensis B115-Based ELISA to Unravel False Positive Serologic Reactions in Bovine Brucellosis: A Field Study ... All positive sera, i.e. from Brucella-infected animals, were RBPT positive and CFT positive (ICFTU ranging from 20 to 1280) and ... All positive sera, i.e. from Brucella-infected animals, were RBPT positive and CFT positive (ICFTU ranging from 20 to 1280) and ...
The porcine brucellosis - evidence of the role of Yersinia enterocolitica O:9 in occurrence of false positive serological...
9 in occurrence of false positive serological reactions - Polish Journal of Veterinary Sciences ... 9 in occurrence of false positive serological reactions. M. Weiner; K. Szulowski; W. Iwaniak ... The porcine brucellosis - evidence of the role of Yersinia enterocolitica O:9 in occurrence of false positive serological ...
Kovacs F[au] - PubMed - NCBI
Slater revisited: 6 year follow up study of patients with medically unexplained motor symptoms | The BMJ
The frequency and identification of false positive conversion reactions. J Nerv Ment Dis 1979;167:243-247. ... Diagnosed conversion reactions: predicative value of psychiatric criteria. JAMA 1966;197:530-534. ... Neurologists should be encouraged to make a positive diagnosis early to avoid uncertainty in the minds of the patients, and ... Prognosis and differential diagnosis of conversion reactions. Dis Nerv System 1962;23:623-631. ...
False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck...
False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck ... False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck ... False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck ... T1 - False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and ...
False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck...
Reverse Transcriptase Polymerase Chain Reaction / False Positive Reactions / Betacoronavirus Type of study: Diagnostic study / ... Reverse Transcriptase Polymerase Chain Reaction / False Positive Reactions / Betacoronavirus Type of study: Diagnostic study / ... Reverse Transcriptase Polymerase Chain Reaction / False Positive Reactions / Betacoronavirus Subject: Pneumonia, Viral / ... Reverse Transcriptase Polymerase Chain Reaction / False Positive Reactions / Betacoronavirus Subject: Pneumonia, Viral / ...
Computerized detection of pulmonary nodules in computed tomography images.
Hematologic scoring system in early diagnosis of sepsis in neutropenic newborns.
False Positive Reactions. Hematologic Tests*. Humans. Infant, Newborn. Infant, Premature, Diseases / blood, diagnosis, etiology ... 16.5%; P , 0.001). On the initial test a positive screen (scores , or = 3) identified 26 of 28 infants with sepsis or probable ... infection (sensitivity 93%; specificity 82%; positive and negative predictive values 50 and 98%, respectively). Corresponding ...
Amsler grid test for detection of advanced glaucoma in Ethiopia.
False Positive Reactions. Positive test results in subjects who do not possess the attribute for which the test is conducted. ... False Negative Reactions. Negative test results in subjects who possess the attribute for which the test is conducted. The ... and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of ...
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reaction from me are its false positives. Even something as simple as typing a message with some "random" keywords which set it ... Here is my reaction to it: So I check my logs a few times a week, searching for the 406 errors. All of these "probes" are for ... Dont let mod_security give you a false sense of security.. Stefan Esser wrote:. mod_security might be good to stop known worms ...
SpecificitySyphilisAntibodiesPolymeraseEnzyme-linkeSerumHumansTuberculinAdverse drug reacNegativesOccurDiagnosisResultsSerological testsSeraReactivityAllergicInfectionResultTestsNegative predictive valuesInfectiousComputed tomographyReproducibleSkin reactionsFalselyImmunoglobulinPatientsTuberculosisClinicalCitationJaffeAssaysIsolatesDetectionDescriptorIndurationLaboratoryConcentrationsNonspecificAntibioticsCreatinineMethodsRheumatoidPersists
Specificity2
- To evaluate false-positivity and specificity, 54 HIV false-positive and HIV-negative serum samples from 100 hospitalized patients and 600 healthy subjects were included. (curehunter.com)
- Raising temperatures or shaking speeds accelerated RT-QuIC reactions without compromising specificity. (mdpi.com)
Syphilis14
- The Venereal Disease Research Laboratory (VDRL) test for syphilis screening may, under certain circumstances, yield positive results in patients not infected with Treponema pallidum, a phenomenon referred to as biological false-positive (BFP) VDRL test. (nih.gov)
- The seroprevalence for syphilis was 1.77% (n = 5320), as determined by a positive TPHA test. (nih.gov)
- In a low syphilis prevalence population, BFP reactions comprise a high proportion of all VDRL reactors. (nih.gov)
- The evaluation of positive serologic tests for syphilis is a problem which every physician must face. (annals.org)
- Problem sera from 375 blood donors were investigated for biological false-positive reactions to serological tests for syphilis. (bmj.com)
- Of the sera 49·9% were found to be non-reactive in all five tests, 28·8% gave results indicating a diagnosis of syphilis, and 21·3% showed biological false-positive reactions. (bmj.com)
- It is concluded that sudden blood loss, as in blood donation, appears to stimulate the production of excess reagin in certain individuals, causing a chronic biological false positive reaction to serological tests for syphilis. (bmj.com)
- We reviewed the serological test results of patients tested for syphilis in our hospital in the past decade and described the clinical characteristics of patients with BFP reactions. (bmj.com)
- The prevalence of biologic false-positive (BFP) reactions for syphilis (reactive rapid plasma reagin [RPR] test, nonreactive fluorescent treponemal antibody absorption [FTA-ABS] test) among patients attending two sexually transmitted disease (STD) clinics was evaluated to assess relationships between BFP reactions and human immunodeficiency virus (HIV) infection. (elsevier.com)
- Although more common among HIV-infected than HIV-uninfected patients, BFP reactions are relatively rare among STD clinic patients, and 89% of patients with reactive RPR or VDRL serologic tests for syphilis had current or prior syphilis infection. (elsevier.com)
- Prevalence of syphilis and biological false positive reactions in VDRL test among injecting drug users: a preliminary study. (bvsalud.org)
- False positive serologic reactions for syphilis: due to smallpox vaccinations (vaccinia). (springer.com)
- Koike T, Sueishi M, Funaki H, Tomioka H, Yoshida S. Anti-phospholipid antibodies and biological false positive serological test for syphilis in patients with systemic lupus erythematosus. (springer.com)
- The interpretation of syphilis tests is further complicated by the lack of a reliable gold standard for syphilis diagnostics, and the newer tests can result in false-positive reactions similar to those seen with older tests. (asm.org)
Antibodies7
- The results of the various methods of assaying anti-tTG antibodies in patients with LC are highly variable, and the positives found are generally false positives, partly due to the high immunoglobulin concentration. (nih.gov)
- IFAT reveals the earliest positive results for IgM antibodies after initial infection. (medscape.com)
- In a large study of 494 patients with infectious mononucleosis, 79% of cases were due to EBV, and, in the 73 heterophile antibody-negative patients, approximately half of these were CMV positive (rising complement-fixing antibodies). (medscape.com)
- I have read that sometimes false positive reflect a reaction to other (non-HIV) antibodies. (thebody.com)
- This would probably mean that the blood that is negative when diluted but positive when undiluted has a lower level of antibodies than the diluted blood that is doubly positive and, therefore, may probably test negative on the Western blot test. (whale.to)
- Participants were selected should respond, regardless of the test used, be it from five Voluntary HIV Counselling Testing (VCT) negative (absence of specific anti-HIV antibodies) or sites at the health centres of Neema and Boyoma in positive (presence of specific anti-HIV antibodies). (who.int)
- If the patient has antibodies to T. pallidum , a color reaction takes place. (cdc.gov)
Polymerase7
- The collection of biological material (e.g., blood) directly onto filter paper for subsequent use in laboratory assays such as polymerase chain reaction (PCR), has become a common practice. (edu.au)
- Background: No reports describe falsepositive reverse transcriptase polymerase chain reaction (RT-PCR) for novel coronavirus in preoperative screening. (elsevier.com)
- The recently developed polymerase chain reaction (PCR) and DNA-probe methods provide additional means of detection. (fao.org)
- This is 'Polymerase Chain Reaction' testing in which tissues are homogenized and then a probe is used to find tiny bits of the virus DNA. (koivet.com)
- AIMS/BACKGROUND The purpose of this study was apply the polymerase chain reaction (PCR) to develop a sensitive, specific, and rapid test to diagnose Fusarium keratitis. (bmj.com)
- The polymerase chain reaction (PCR) technique permits the in vitro copying and recopying of a selected DNA sequence in a series of denaturation, reannealing, and extension steps in the presence of synthetic oligonucleotide primers and heat stable DNA polymerase. (bmj.com)
- Virus can be detected in the blood for 1-2 weeks by nucleic acid tests such as polymerase chain reaction. (bmj.com)
Enzyme-linke2
- The reactivity of positive samples should be confirmed by the complement fixation test or by enzyme-linked immunosorbent assay (ELISA), both of which can also be used for both screening and confirmation. (fao.org)
- One-hundred and sixty-four migrants from Sub-Saharan Africa to Italy were screened with the Taenia solium specific enzyme-linked immunosorbent assay coproantigen (ELISA CoAg) and four (2.4%) were recorded as positive, but with optical density values near to the cut-off. (mdpi.com)
Serum7
- On each serum a cardiolipin Wassermann reaction, a Venereal Disease Research Laboratory test, a Reiter protein-complement fixation test, a Treponema pallidum immobilization test, and a fluorescent treponemal antibody absorption test were performed. (bmj.com)
- Systemic toxic reactions are usually associated with much higher serum levels (30 to 40 mg/100 ml). (drugs.com)
- Hepatic Cirrhosis Showing False-Positive Serum C-Reactive Protein Reaction. (nii.ac.jp)
- A false-positive test has been reported with serum sickness ( CID 1999;29:953). (lww.com)
- Positive and negative control serum specimens are run simultaneously to allow identification of viral proteins. (cdc.gov)
- This reality was recently mentioned by an internationally-famous virologist from Germany, in an interview where he also admitted that laboratory confirmation of COVID-19 is next to impossible given the high incidence of both false-positive COVID PCR swab tests and false positive COVID serum antibody tests. (lewrockwell.com)
- Recombinant EryC, Omp16, PP26, and PP39 were all reactive to B. abortus-positive serum. (mendeley.com)
Humans1
- All of these tests have been reported to provide positive results in more than 95% of the sera from infected humans. (medscape.com)
Tuberculin15
- Persons showing positive tuberculin reactions should be considered positive by current public health guidelines and referred for further medical evaluation. (drugs.com)
- Characteristically, delayed hypersensitivity reactions to tuberculin begin at 5 to 6 hours, are maximal at 48 to 72 hours and subside over a period of days. (nih.gov)
- Clinically, a delayed hypersensitivity reaction to tuberculin is a manifestation of previous infection with M tuberculosis or a variety of non-tuberculosis bacteria. (nih.gov)
- Allergy to any component of TUBERSOL or an anaphylactic or other allergic reaction to a previous test of tuberculin PPD is a contraindication to the use of TUBERSOL. (nih.gov)
- The only evidence of infection may be a reaction to a tuberculin skin test. (cdc.gov)
- Health-care agencies or other facilities should consult with the local health department before starting a skin-testing program to ensure that adequate provisions are made for the evaluation and treatment of persons whose tuberculin skin tests are positive. (cdc.gov)
- The tuberculin reaction was first described by Robert Koch in 1890. (wikipedia.org)
- However, the test was unreliable due to impurities in tuberculin which tended to cause false results. (wikipedia.org)
- TST (tuberculin skin test) positive is measured by size of induration. (wikipedia.org)
- A positive Mantoux tuberculin skin test is the hallmark of tuberculous infection, meaning that the person harbors M tuberculosis within the body. (healio.com)
- If the individual with a positive tuberculin skin test has a negative chest radiograph, a normal physical examination, and no symptoms, he or she has tuberculous infection without disease and, usually, is a candidate for isoniazid therapy. (healio.com)
- In general, a child with a positive Mantoux tuberculin skin test who has any radiographic or clinical manifestations consistent with tuberculosis is considered to have tuberculous disease, even if no symptoms are present. (healio.com)
- The tuberculin skin test is based on the fact that infection with M. tuberculosis bacterium produces a delayed-type hypersensitivity skin reaction to certain components of the bacterium. (medicinenet.com)
- Reaction in the skin to tuberculin PPD begins when specialized immune cells, called T cells, which have been sensitized by prior infection, are attracted by the immune system to the skin site where they release chemical messengers called lymphokines. (medicinenet.com)
- It is only contraindicated in people who have had a severe reaction to a previous tuberculin skin test. (medicinenet.com)
Adverse drug reac3
- Adverse drug reactions (ADRs) remain a common and major problem in healthcare. (hindawi.com)
- Severe cutaneous adverse drug reactions (SCARs), such as Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with mortality rate ranges from 10% to more than 30%, can be life threatening. (hindawi.com)
- In rare cases, some drugs are capable of inducing immune responses through interactions with MHC molecules, known as adverse drug reactions (ADRs). (hindawi.com)
Negatives3
- So false NEGATIVES may occur. (koivet.com)
- Always send more than one fish, because among a group, there will be false negatives. (koivet.com)
- Niven's medium ( 48 ) has been most widely used, although high rates of false positives and false negatives are observed, presumably due to the presence of competing bacteria ( 12 , 25 , 39 ). (asm.org)
Occur5
- Two false positive reactions did occur in the CF test. (ajtmh.org)
- Systemic reactions, such as hand dermatitis or generalized eczematous reactions, can occur due to dietary nickel or cobalt ingestion. (hindawi.com)
- With nontreponemal tests, false-positive reactions can occur because of pregnancy, autoimmune disorders, and infections. (aafp.org)
- Cross reactions and false positives may occur. (koivet.com)
- Cross-reactions with false-positive results may occur with B. fragilis, Pseudomonas species, Stenotrophomonas and Flavobacterium. (lww.com)
Diagnosis6
- Regardless of their individual experiences of cancer within the family, faith in the ability of mammography to detect a cancer at an early stage gave reassurance that a cancer diagnosis could lead to a positive outcome. (biomedcentral.com)
- Conclusions: The B. melitensis B115-based ELISA systematically unravelled all false positive (FP) sera while confirming the diagnosis in Brucella-infected animals. (researchsquare.com)
- But late in 2004 we came to realize that some people in our program did not have HIV, so we re-tested a number of them-and identified almost 50 who were suspect for false positive HIV diagnosis. (plos.org)
- This news was devastating, considering the consequences a false diagnosis can have on people's lives. (plos.org)
- All patients with a suspected false diagnosis were counseled and re-tested using the confirmation test. (plos.org)
- The new test is specific in confirming the diagnosis so when it's positive, we can be very sure it means allergy," Dr Alexandra Santos, an MRC Clinician Scientist at King's College London, said in a press release. (upi.com)
Results23
- Men who get a "false-positive" prostate cancer result -- an abnormal screening test followed by a biopsy indicating no evidence of cancer -- appear more likely to worry about their subsequent risk of cancer and report more problems with sexual function compared to men with normal screening results, according to a University of Iowa study. (bio-medicine.org)
- Positive test results in subjects who do not possess the attribute for which the test is conducted. (ucdenver.edu)
- In this article, we test the hypothesis that randomized clinical trials of acupuncture for pain with certain design features (A + B versus B) are likely to generate false positive results. (isharonline.org)
- They all suggested that acupuncture is effected (one only showing a positive trend, all others had significant results). (isharonline.org)
- We conclude that the 'A + B versus B' design is prone to false positive results and discuss the design features that might prevent or exacerbate this problem. (isharonline.org)
- The use of a common cutting instrument for excising a standard-sized piece of paper that contains the material also introduces the potential for transferring biological material from one sample to subsequent samples, causing false-positive results by PCR. (edu.au)
- It was determined that false-positive results could be obtained at least 13 times after a positive sample. (edu.au)
- This method was simple, cheap, and relatively rapid, and allowed for the use of a single hole punch for a series of samples, without carryover contamination and consequent false-positive results. (edu.au)
- Four (9.3%) had discrepant results (positive/negative). (elsevier.com)
- RESULTS: The system provided a sensitivity of 94% for nodule detection and an average of 1.25 false-positive results per case. (biomedsearch.com)
- Blood cultures have positive results in 100% of patients with acute-phase illness, but only 40-50% in those with chronic illness. (medscape.com)
- Test results are positive in approximately 50% of individuals. (medscape.com)
- Only 34 of the 54 (63%) samples known to yield false-positive results by EHIV assay had repeatedly yielded reactive results in the CHIV assay. (curehunter.com)
- False-negative ratio refers to the ratio of subjects affected by an illness whose test results wrongly suggest they are disease free to all those subjects who have the disease. (ebscohost.com)
- They work well for screening blood transfusions and identifying people who need further tests, but are known to yield false positive results due to serological cross-reactivity (or to inadequate quality control and human error (e.g. mislabeling of specimens). (plos.org)
- Preliminary urine screening results, when positive, should be confirmed by a more accurate method that can distinguish between poppy seed ingestion and use of heroin or other opiates. (minddisorders.com)
- Positive screening results should always be confirmed by a more sensitive method. (minddisorders.com)
- If the sensitivity of the test is poor, it will give significant false-negative results. (google.com)
- If its not due to some other reason then I'm confused by the posts where people said their Herpeselect test were negative but IgM was positive and they were told they should disregard the IgM results. (medhelp.org)
- The method, however, carries a risk of severe, life-threatening allergic reaction, in addition to false-positive results. (upi.com)
- Diagnostic antibody tests can give false positive results because of cross reaction against related viruses such as dengue. (bmj.com)
- Based on the results of this study the EC3 value is calculated to be 64.9% v/v. The SI for the positive control substance hexyl cinnamic aldehyde (HCA) was 6.5 which demonstrates the validity of this study. (europa.eu)
- [15] In positive psychology , anxiety is described as the mental state that results from a difficult challenge for which the subject has insufficient coping skills. (wikipedia.org)
Serological tests1
- Brucellin preparations for the intradermal test must be free of lipopolysaccharide and must not produce non-specific inflammatory reactions or interfere with serological tests. (fao.org)
Sera8
- Biological false-positive tests comprise a high proportion of Venereal Disease Research Laboratory reactions in an analysis of 300,000 sera. (nih.gov)
- There were 80 sera from blood donors which gave biological false-positive reactions. (bmj.com)
- Sixty-six of the sera showed chronic biological false-positive reactions. (bmj.com)
- RBPT positive and CFT negative, as well as double positive (DP) sera, i.e. (researchsquare.com)
- All positive sera, i.e. from Brucella-infected animals, were RBPT positive and CFT positive (ICFTU ranging from 20 to 1280) and gave ELISA O.D. values above the cutoff. (researchsquare.com)
- Despite its great sensitivity, the CMV IgM test is limited by a one-way cross-reaction of acute EBV infectious mononucleosis sera. (medscape.com)
- In all tests, eight of nine sera from patients with larva currens were positive. (asm.org)
- The prevalence of HIV-1 and HIV-2 co-infection among HIV positive sera was 16.7% (95% CI: 4.7 - 44.8). (who.int)
Reactivity2
- With regard to reactivity in VDRL testing, 2799 patients (0.92%) of the study population were positive, of whom 736 (26%) were biological false positive. (nih.gov)
- This proportion might be even higher, as reactivity in the VDRL at 1:0 and 1:2 dilutions without a positive treponemal test was not reported. (nih.gov)
Allergic5
- We would reduce by two-thirds the number of expensive, stressful oral food challenges conducted, as well as saving children from experiencing allergic reactions. (upi.com)
- If we relied on them alone, we'd be over diagnosing food allergies -- only 22 percent of school-aged children in the U.K. with a positive test to peanuts are actually allergic when they're fed the food in a monitored setting. (upi.com)
- The new test concentrates on mast cells, which help trigger allergic reactions. (upi.com)
- They recognize an antibody called immunoglobulin in plasma and, in allergic patients, produce biomarkers associated with allergic reactions. (upi.com)
- Parents are often afraid to feed them a food that is known to cause allergic reactions. (upi.com)
Infection7
- In this study, we evaluated the performance of a new fourth-generation ADVIA Centaur HIV antigen /antibody combo (CHIV) assay (Siemens Healthcare Diagnostics Inc., USA) for early detection of HIV infection and reduction of false positive rate. (curehunter.com)
- The performance characteristics of these tests were influenced negatively by concomitant HIV infection and the presence of other genital ulcer disease pathogens in lesions found to be Treponema pallidum PCR positive. (thefreelibrary.com)
- This means that in groups of known-positive KHV infection, you have a one-or-two out of three chance of actually finding it. (koivet.com)
- Therefore, a test for IgM antibody to any particular infection may be positive before a test that detects IgG antibody. (medhelp.org)
- Bottom lines: Sometimes a new HSV infection in an adult indeed will be positive by IgM before IgG. (medhelp.org)
- Although Mallein is the most commonly used form of testing for glanders, cross reactions were reported between Burkholderia mallei and Streptococcus equi, which is a bacteria-caused contagious upper respiratory tract infection of equines. (wikipedia.org)
- If certain other vertically transmissible infections are suspected because of a positive antenatal test result, confirmatory tests for maternal and, if indicated, fetal infection are essential before intervention is considered (eg, cytomegalovirus infection). (mja.com.au)
Result15
- This complementary qualitative study explored the value women placed on having joined a programme of regular screening, and sought to understand the reactions of women who had received an initial all-clear result and who had received an all-clear result following further tests. (biomedcentral.com)
- Reactivation of the virus is not uncommon, sometimes occurring with viremia and a positive IgM result in the presence of IgG antibody. (medscape.com)
- A test result that wrongly suggests that a particular disease or condition is not present is referred to as false negative. (ebscohost.com)
- An example of a false positive is a mammography result which suggests that a patient's has breast cancer, but subsequent. (ebscohost.com)
- False-negative reaction refers to a test result that is negative in an individual who nonetheless has the attribute or disease being tested for. (ebscohost.com)
- False-positive reaction refers to a test result that is positive in a person who is actually healthy. (ebscohost.com)
- Certain foods, such as poppy seeds, may result in a positive urine screen for opiates, since poppy seeds are derived from opium poppies. (minddisorders.com)
- The person's medical risk factors determine at which increment (5 mm, 10 mm, or 15 mm) of induration the result is considered positive. (wikipedia.org)
- [7] A positive result indicates TB exposure. (wikipedia.org)
- The size of the induration considered to be a positive result depends on risk factors. (wikipedia.org)
- Interpretation of semiquantitative reagent strips, which are colorimetric tests, requires knowledge of urine color because discolored urine may result in a false-positive result. (merckvetmanual.com)
- Could either of these medications produce a false negative or false positive result? (thebody.com)
- The currently licensed Du Pont Western blot test specifies that the test result should be interpreted as positive only when the detected bands include p24 and p31, and gp41 or gp120/160 (12) (see Table 2). (cdc.gov)
- Low positivity could be attributed to false positive result or cross-reaction with other Taenia species. (mdpi.com)
- Which of the following situations can result in a false-negative reaction with Rh typing reagents? (labce.com)
Tests11
- The subgroup of HIV-positive patients (n = 1415) revealed a 10-fold higher rate of BFP tests (2.1% versus 0.24), an effect being statistically significant. (nih.gov)
- Neither of the two tests is able to avoid the detection of false positive serological reactions (FPSRs) caused by bacteria sharing S-LPS components with Brucella spp. (researchsquare.com)
- Positive tests were repeated. (elsevier.com)
- A persistent problem with these tests is false-positive reactions. (medscape.com)
- The IHA and the LF tests were more specific in that no false positive reactions occurred. (ajtmh.org)
- The difficult topic: false positive HIV tests. (plos.org)
- The 2 study sites initially showed a 7% false positive rate using the national algorithm, which relies on 2 out of 3 positive tests ("tie-breaker" algorithm). (plos.org)
- A patient taking prescribed codeine pills and an individual using heroin would both show positive urine screening tests for opiates. (minddisorders.com)
- This reaction is the basis of traditional nontreponemal tests such as the VDRL test and rapid plasma reagin test. (aafp.org)
- First, false positive tests are common--that is, apparent IgM antibody that simply isn't present at all, despite what the test says. (medhelp.org)
- What I noticed is that the absorbance values of the specimens that tested negative when diluted [1: 400], but positive when undiluted [1:1], had lower values than the samples that, diluted, react positive on both the ELISA and Western blot tests. (whale.to)
Negative predictive values1
- positive and negative predictive values 50 and 98%, respectively). (biomedsearch.com)
Infectious1
- Adults with extensive pulmonary disease, frequent cough, and heavy sputum production that is acid-fast smear positive are most likely to be infectious. (healio.com)
Computed tomography1
- Conclusions: If false positives are suspected, we recommend computed tomography (CT) of the chest and repeat RT-PCR. (elsevier.com)
Reproducible1
- Studies have shown that not all positive patch test reactions are reproducible upon retesting, that is, persistent. (bioportfolio.com)
Skin reactions1
- skin reactions (+1 or +2) in 70-90% of sensitive subjects. (bioportfolio.com)
Falsely1
- Or because the test is often falsely positive for some other reason? (medhelp.org)
Immunoglobulin2
- There was no statistically significant correlation between RPR titre and total protein albumin gap, surrogate of immunoglobulin levels among patients with BFP reactions. (bmj.com)
- KIR have either two (KIR2D) or three (KIR3D) extracellular immunoglobulin domains and either short (S) or long (L) intracytoplasmic tails which transduce positive and negative signals, respectively ( 4 - 7 ). (rupress.org)
Patients7
- However, only a few recent reports described the incidence and clinical characteristics of patients with BFP reactions. (bmj.com)
- Clinical characteristics and laboratory data of patients with BFP reactions were reviewed manually. (bmj.com)
- Most BFP reactions were observed in patients aged over 60 years, with a history of malignancy and autoimmune diseases. (bmj.com)
- BFP reactions were more likely to persist beyond 6 months among patients with RPR titre of ≥1:8. (bmj.com)
- False-positive reactions in patients with lung cancer limit the usefulness of ELISA with conventional anti-BCG antibody for detection of M. tuberculosis antigen. (microbiologyresearch.org)
- and even when truly positive, there is no distinction between HSV-1 and HSV-2, which is pretty important to most patients and providers. (medhelp.org)
- To diagnose peanut allergy, medical personnel give legume substances to patients in incrementally larger doses, testing for a reaction. (upi.com)
Tuberculosis1
- A person who received a BCG vaccine (administered in some countries but not the U.S.) against tuberculosis may also have a positive skin reaction to the TB test. (medicinenet.com)
Clinical2
- To evaluate the safety of Disperse blue 106 and Bronopol T.R.U.E. Test allergens in 20 adult subjects per allergen with a clinical history of contact dermatitis and a positive patch test to the respective reference allergen. (bioportfolio.com)
- Additional information needed The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. (wikipedia.org)
Citation1
- citation needed] This resulted in false-positive reactions. (wikipedia.org)
Jaffe3
- In 1886, Max Jaffe (1841-1911) wrote about its basic principles in the paper Über den Niederschlag, welchen Pikrinsäure in normalem Harn erzeugt und über eine neue Reaction des Kreatinins in which he described the properties of creatinine and picric acid in an alkaline solution. (wikipedia.org)
- The Jaffe reaction, despite its nonspecificity for creatinine, is still widely employed as the method of choice for creatinine testing due to its speed, adaptability in automated analysis, and cost-effectiveness, and is the oldest methodology continued to be used in the medical laboratory. (wikipedia.org)
- It was Otto Folin (1867-1934), a Harvard biochemist, who adapted Jaffe's research-abandoning the standard Neubauer reaction of the time-and published several papers using the Jaffe reaction to analyze creatinine levels in both blood and urine. (wikipedia.org)
Assays1
- The assay is sensitive and, unlike prior sandwich assays for the antigen, is not affected significantly by cross-reactions with rheumatoid factor. (google.com)
Isolates2
- 13 and 8 isolates were false positive by the bacteriophage-based and Pastorex LATs, respectively. (asm.org)
- The histamine-forming capability of positive isolates was not confirmed in all reports, and some reports ( 52 , 54 ) described false-positive reactions in some media due to the formation of alkaline compounds or false-negative responses due to fermentation by some bacteria. (asm.org)
Detection1
- The challenges include robust object tracking, stationary object detection, reactions for false positives etc. (sae.org)
Descriptor1
- False Positive Reactions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
Induration2
- For persons who are otherwise at low risk and are tested at the start of employment, a reaction of ≥15 mm induration is considered positive. (drugs.com)
- The reaction is read by measuring the diameter of induration (palpable raised, hardened area) across the forearm (perpendicular to the long axis) in millimeters. (wikipedia.org)
Laboratory1
- The positive control group received 25% v/v hexylcinnamic aldehyde in AOO based on previous experience at this laboratory. (europa.eu)
Concentrations1
- The thinness of the stratum corneum and intermittent exposure to sweat on the eyelids have been associated with increased nickel absorption through the skin from cosmetics, allowing lower nickel concentrations to elicit a reaction [ 4 ]. (hindawi.com)
Nonspecific2
- Although he found the amount of precipitate directly proportional to the creatinine concentration, he also noted that the reaction was highly nonspecific and could be observed with many other organic compounds. (wikipedia.org)
- Paget cells showed a conspicuous positive reaction with antiserum to CEA, but were negative when nonspecific cross-reacting-antigen (NCA)-absorbed antiserum to CEA, or a monoclonal antibody to CEA was used as the detecting agents. (wikigenes.org)
Antibiotics1
- Patch-test readings after day 5 have previously been used to identify delayed reactions to metals and topical antibiotics. (bioportfolio.com)
Creatinine1
- The color change that occurred was directly proportional to the concentration of creatinine, however he also noted that several other organic compounds induced similar reactions. (wikipedia.org)
Methods2
Rheumatoid1
- False-positive reactions have resulted from the presence of rheumatoid factors. (medscape.com)
Persists1
- The test is positive within one day of onset of symptoms and persists for days to weeks, and in one case persisted over 300 days ( JCM 1984;20:605). (lww.com)