Morphological and physiological development of EMBRYOS or FETUSES.

No data available that match "factor superovulation"


Endometrial glands secrete molecules hypothesized to support conceptus growth and development. In sheep, endometrial gland ... Embryonic Development*. Embryonic and Fetal Development*. Endometrium / anatomy & histology, drug effects, physiology*. Female ... Previous Document: B-Myc, a proximal caput epididymal protein, is dependent on androgens and testicular factors for exp.... ... Superovulation. Ultrasonography, Prenatal. Grant Support. ID/Acronym/Agency: P30 ES09106/ES/NIEHS NIH HHS ...
Fertility and Development is an international journal publishing original research , review and comment in the fields of ... RDv24n1Ab8989 PHENAZINE ETHOSULFATE AND FETAL CALF SERUM EFFECT IN THE ULTRASTRUCTURE AND DEVELOPMENT OF IN VITRO-PRODUCED ... RDv24n1Ab216216 EMBRYONIC AND INDUCED PLURIPOTENT STEM CELLS ANALOGOUS TO INNER CELL MASS-DERIVED LIF-DEPENDENT MOUSE EMBRYONIC ... RDv24n1Ab6767 SUPPLEMENTATION WITH EPIDERMAL GROWTH FACTOR AND GLIAL CELL-DERIVED NEUROTROPIC FACTOR DURING PORCINE OOCYTE ...
"Functional Role of CHD1 during Bovine Early Embryonic Development.". *Short Oral Presentation: Laura Whidden (McGill University ... "Serum Replacement Alters Somatic and Germ Cell Development in Ex-Vivo Mouse Fetal Gonad Culture." ... Invited Talk: Mellissa R.W. Mann, Ph.D. (University of Western Ontario, London, Ontario, Canada). "Impact of Superovulation on ... Chaudhuri has made significant contributions to understanding factors that control vascular tone, effect of estrogens on ...
Van der Auwera, I, and DHooghe, T (2001). Superovulation of female mice delays embryonic and fetal development. Hum Reprod. 16 ... Chi, S, Cao, H, Wang, Y, and McNiven, MA (2011). Recycling of the epidermal growth factor receptor is mediated by a novel form ... and delayed embryonic and fetal development (Van der Auwera and DHooghe, 2001). Injection of hormones at supra-physiological ... the model effect of superovulation on preimplantation development was not (p , 0.4) detected. The developments to the 2-cell, 4 ...
It has been well established that vaginal parity, notably the first, is an independent risk factor for the future development ... and the latter encompasses the embryonic and fetal periods. Preimplantation is characterized by transport of the zygote from ... Ovulation is perturbed, but can be returned to a normal level by treatments used to obtain superovulation. Nevertheless, even ... Obstetric Factors Last Updated on Sat, 13 Jul 2019 , Pelvic Floor Obstetric injury is thought to be a principal factor ...
... in vitro and in vivo development of embryos; factors affecting embryo development in vitro, and embryo culture, embryo freezing ... Transuterine migration and loss of eggs; Embryonic development in oviduct; Fertilization, Cleavage and implantation; Gestation ... Laboratory methods†Pregnancy diagnosis in cow, mare, ewe and sow; Embryo Transfer†Superovulation, collection of ova, ... Fetal Maceration; revention of Conception and induction of Abortion; Extra†uterine pregnancies and fetuses; Dropsy of the ...
Van der Auwera I, DHooghe T. Superovulation of female mice delays embryonic and fetal development. Hum Reprod. 2001;16(6):1237 ... Furthermore, our data implicate overexpressed uterine Cox2 and IL-15 as causal factors in the poor fetoplacental development ... retarded fetal development, and poor pregnancy outcomes, such as PE and fetal growth restriction. The precise mechanism(s) of ... period resulted in inferior fetal growth and placental development and reduced dNK cell numbers at the maternal-fetal interface ...
... cause problems with fetal development.. For a long while, conventional wisdom held that sperm cells didnt have any RNA because ... and events required for fertilization and early embryonic development," says Dolores Lamb at the Baylor College of Medicine, ... "A lot of things have been done to tweak superovulation regimens and things like that. But little has been done about the sperm ... There is no template." This has implications for older men, because age has been suggested to be a factor in creating more ...
Embryonic erythropoiesis in vertebrates is characterized by development of pluripotent hematopoietic stem cells from embryonic ... Litter size in swine is controlled by several factors, including ovulation rate, uterine capacity, and fetal survivability. ... Previous studies attempting to increase litter size in pigs by superovulation, genetic selection for ovulation rate, or embryo ... Hallmarks of fetal development in swine at this time include organogenesis and sexual differentiation. Failure of sexual ...
Epigenetic Modifications and Embryonic Development. Epigenetic modifications are small chemical tags which can be added ... the central goal being to determine their role at the maternal-fetal interface and the long-term impact on child development ... Temporal expression of factors involved in chromatin remodeling and in gene regulation during early bovine in vitro embryo ... Modulation of imprinted gene expression following superovulation. Mol Cell Endocrinol. May 5;388(1-2):51-7. ...
... initiated during embryonic development. Postnatal sexual development is dominated by negative feedback of estradiol in ... Sexual development is influenced by both genetic and environmental factors. In does and bucks the age at puberty ranges from ... When fetal numbers can be determined as part of the pregnancy diagnosis, different feeding regimes can be applied to single and ... Superovulation. As multiple litter bearing animals, ovulation rate and litter size have a major impact on the reproductive ...
If these coping mechanisms are overwhelmed, improper maternal-foetal exchanges occur, potentially leading to adverse pregnancy ... when the development of the embryo continues, the placenta could bring adaptive responses throughout pregnancy. Amongst the ... different mechanisms, epigenetics, especially thanks to a finely tuned network of imprinted genes stimulated by foetal signals ... In some cases, it results in embryonic growth arrest but, ... Superovulation of female mice delays embryonic and fetal ...
2016) Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration. Biochem J ... 2014) Long-term effects of repeated superovulation on ovarian structure and function in rhesus monkeys. Fertil Steril 102(5): ... 2014) Comparative Proteomic Profile of the Human Placenta in Normal and Fetal Growth Restriction Subjects. Cell Physiol Biochem ... 2011) Phosphorylation of Human Eukaryotic Initiation Factor 2γ: Novel Site Identification and Targeted PKC Involvement. J ...
Among all the reproductive technologies, cloning with embryonic and foetal cells has progressed dramatically in sheep and ... Superovulation, in vitro maturation, embryo freezing, nuclear transfer, transgenesis, sheep. Superovulation, maturation in ... is necessary to prevent abnormal foetal development. Cette revue traite du transfert dembryons et des principales ... Further research is required to identify factors able to promote the maturation in vitro of oocytes, namely those obtained from ...
Jones CA, Sigmund CD, McGowan RA, Kane CM, and Gross KW. Expression of murine renin genes during fetal development. Mol ... Expression of a renin/GFP transgene in mouse embryonic, extra-embryonic, and adult tissues. C. A. JONES, M. I. HURLEY, T. A. ... where they are in a unique position to sense fluctuations in humoral factors and systolic pressure. This localization is the ... C3H/HeRos F1 mice after super-ovulation of immature females (3-5 wk of age). Eggs were collected, microinjected, and ...
9 Early Embryonic Development. Grading of Embryos Based on cell number ~ rate of growth Amount of fragmentation Equal size of ... Pediatrics 2006 Prematurity and multi-fetal gestation are individually independent risk factors for CP After adjustment for ... Review of safety and effectiveness of interventions for ovulation induction, superovulation, & ART 5294 abstracts with review ... 12 Multi-fetal Gestation - Fetal/Infant. Spontaneous abortion Perinatal mortality Preterm birth/low birthweight Fetal growth ...
The unusually rapid growth and development of the cloned goat may have resulted from SCNT-associated epigenetic reprogramming ... this is the first case in which a cloned animal born with a normal weight exhibited accelerated growth and development. ... Superovulation;Oocyte;Cloning;Nuclear Transfer;Telomere; The objectives of the present study were to initiate cloning of Korean ... Factors affecting superovulation and embryo transfer in Boer goats. Asian-Aust. J. Anim. Sci. 19:341-346. https://doi.org/ ...
... regulating such processes as fetal growth and development as well as X inactivation (reviewed in refs. 4-6). Whereas the genome ... Superovulation in B6D2F1 mice (age 8-10 wk) was induced by injection of 5 international units of equine chorionic gonadotropin ... arisen in the factors present in oocyte cytoplasm that reprogram not only the sperm and egg genomes in normal development but ... which appose within the oocyte cytoplasm before the first embryonic mitosis. However, the highly condensed sperm chromatin ...
We compared the localization of TDRD5-EGFP with that of other TDRD proteins and relevant factors in male germ cells. In fetal ... The role of Tudor domains in germline development and polar granule architecture. Development. 133:4053-4062. doi:10.1242/dev. ... embryonic stem cell. IAP. intracisternal A particle. IMC. inter-mitochondrial cement. LINE-1. long interspersed repetitive ... Superovulation was induced in BDF1 females by injecting 5 IU equine chorionic gonadotropin, followed by a second injection of 5 ...
Induction of Follicular Development by Direct Single Injection of Vascular Endothelial Growth Factor Gene Fragments into the ... These two types of blastocysts were transferred separately into surrogates, and fetal development was examined in late ... Several researchers have suggested recently that the embryonic-abembryonic (Em-Ab) axis of the mouse blastocyst is orthogonal ... Two groups of embryos were developed in heifers, after superovulation, until 45 or 100 h postovulation (po) and, after ...
This could be because later embryonic development to the blastocyst stage and beyond is also dependent on maternally ... A crucial factor for implantation in vitrified-warmed embryo transfer is exact synchronization between endometrial maturation ... reducing the risk of OHSS and decreasing patient discomfort and cost without the need for superovulation. Although a trend ... pregnancy rates per embryo transfer cycle and implantation rates per transferred embryos were based on the detection of fetal ...
... insulin-like growth factor 1, epidermal growth factor (EGF), and epithelial cell growth factor to the endometrium. Our group ... established during embryonic and fetal period, was in many ways changed by Tillys group work. They practically demonstrated ... The development of sonography and MRI diagnostics has led to a growing number of early detected anomalies. A large number of ... Because superovulation could lead to altered expression of endometrial genes critical to tissue remodeling and placentation, ...
... which could affect embryonic growth through the production of autocrine factors. ... Development, function and fate of fetal Leydig cells. Semin Cell Dev Biol. 2016;59:89-98.View ArticlePubMedGoogle Scholar. ... In this study, we use naturally cycling rat dams (without superovulation) to characterise sex differences in the pre- ... Lack of effect of sex on pig embryonic development in vivo. J Reprod Fertil. 1996;106:107-10.View ArticlePubMedGoogle Scholar. ...
White, K.L, (2004). Present Status Of Equine Cloning And Clinical Characterization Of Embryonic, Fetal And Neonatal Development ... White, K.L, (1995). Effect of serum extender containing growth factors on development of IVM and IVF bovine embryos. ... Ovulation rate and embryo recovery after superovulation with Ovagen. J. Anim Sci. * ... White, K.L, (1989). Early embryonic development in vitro by co-culture with oviductal epithelial cells in the pig. Biol. Reprod ...
95-99). In the presence of MCCs, there was no difference between the embryonic development of fresh and vitrified mature bovine ... Chicken stem cell factor enhances primordial germ cell proliferation cooperatively with fibroblast growth factor 2, pp. 143-149 ... 1-5). The addition of fetal bovine serum and polyvinylpyrrolidone to the medium is the primary difference between the protocols ... and superovulation system. Kim et al. investigated whether a histone deacetylase inhibitor used in dog to pig interspecies ...
In sheep, uterine development begins during fetal life but is only completed postnatally with proliferation and branching ... Little is known about the embryonic factors that regulate the size of the primordial follicle endowment at birth. A few studies ... mice on Day 4 of natural pregnancy or after superovulation showed retarded development, with the total cell number reduced by ... Thus, transplacental exchange provides for all the metabolic demands of fetal growth and development. The rate of ...
Blockage in genital ridge development Embryonic testicular regression syndrome Lhx9 Transcription factor Blockage in genital ... Importantly its sex chromosome dependence, late embryonic/fetal differential development, complex morphogenic changes, long ... clomiphene citrate - (CC) A fertility drug taken orally to promote the process of follicle/egg maturation in superovulation ... Female Genital Development , Male Genital Development , Female Urogenital Development , Male Urogenital Development ...
2017) Paternal low protein diet programs preimplantation embryo gene expression, fetal growth and skeletal development in mice ... The association between poor paternal diet, perturbed embryonic development, and adult offspring ill health represents a new ... 2014) Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring. Proc Natl Acad ... One key difference between the current study and our previous studies is the use of superovulation and artificial insemination ...
... nonhuman primates occupy a unique niche among species suitable for experimental studies on fertilization and early development ... Hendrickx, A. G., and Binkerd, P E., 1980, Fetal deaths in nonhuman primates, in: Human Embryonic and Fetal Death ( I. H. ... Van Blerkom, J., Henry, G., and Porreco, R., 1984, Preimplantation human embryonic development from polypronuclear eggs after ... Simon, J. A., and Hodgen, G. D., 1989, Macaque embryos produce stage specific angiogenic factors associated with viability, ...
Two factors, insulin-like peptide hormone 3 (INSL3) and androgen, have been shown to be involved with gubernaculum development ... During female development the fetal adrenal gland synthesises DHEA, an oestrogen precursor, converted by the placenta into ... During male embryonic development exposure to high levels of estrogen can lead to genital abnormalities. ... clomiphene citrate - (CC) A fertility drug taken orally to promote the process of follicle/egg maturation in superovulation ...
  • Even if co-existing maternal risk factors (such as BMI, maternal age and infertility status) may affect placental development, the artificial manipulation of gametes and/or embryos could also play a role. (biomedcentral.com)
  • Simple protocols for the cryopreservation of sheep embryos by vitrification are already available and the development of frozen-thawed blastocysts to term is close to the fresh ones. (uniss.it)
  • However, a better understanding of the changes in gene expression, induced in embryos by different in vitro manipulation procedures, is necessary to prevent abnormal foetal development. (uniss.it)
  • 2000. Developmental rates of male bovine nuclear transfer embryos derived from adult and fetal cells. (koreascience.or.kr)
  • In contrast, active demethylation of the paternal genome is not observed in early sheep or rabbit embryos (with an intermediate state in the cow) ( 12 ), which suggests that it is not an obligate requirement for mammalian development. (pnas.org)
  • Ammonium levels build up linearly over time in the culture medium when media containing amino acids are incubated at 37°C. Ammonium in the culture media significantly reduces blastocyst cell number, decreases inner cell mass development, increases apoptosis, perturbs metabolism, impairs the ability of embryos to regulate intracellular pH, and alters the expression of the imprinted gene H19 . (bioone.org)
  • Furthermore, of those embryos that manage to implant, fetal growth is significantly impaired. (bioone.org)
  • It is therefore essential that culture conditions for mammalian embryos are designed to minimize the buildup of ammonium to prevent abnormalities in embryo physiology, genetic regulation, pregnancy, and fetal development. (bioone.org)
  • Based on the results obtained for the studies of in vitro development of cloned embryos, epigenetic modifications have been widely used for cloning farm animals. (reproduction.jp)
  • Suberoylanilide hydroxamic acid during in vitro culture improves development of dog-pig interspecies cloned embryos but not dog cloned embryos. (reproduction.jp)
  • However, unfortunately, SAHA treatment for dog to pig iSCNT embryos was not sufficient to improve their in vivo development because three and one clones were successfully produced from the control and SAHA treated groups, respectively. (reproduction.jp)
  • Research with rodent species continues to provide the bulk of basic information on early development, in large part because of the ready availability of oocytes and embryos, but it is difficult to know to what extent information can be extrapolated to primate species, including humans. (springer.com)
  • However, the amount and quality of basic scientific data on early development that can be obtained from this source are restricted, in part by ethical constraints (Austin, 1990) and in part by conflicting priorities between research and clinical needs for the supply of oocytes and embryos. (springer.com)
  • If embryo freezing facilities are available, then supernumerary embryos can be stored, and this needs to be factored in as well. (drmalpani.com)
  • Here we show that the early embryonic deficiency associated with GATA6-knockout mice can be overcome by providing GATA6-null embryos with a wild-type extraembryonic endoderm with the use of tetraploid embryo complementation. (asm.org)
  • Moreover, development of Gata6 − / − embryos arrests during gastrulation with a phenotype that is very similar to that associated with Hnf4 − / − embryos, which is consistent with GATA6 acting upstream of HNF4 during development ( 4 , 20 , 27 ). (asm.org)
  • Transcription of Notch1-2 , Jagged1-2 and Hes1 was highly prevalent and dynamic along stages of development, whereas transcription of Notch3-4 , Dll4 and Hes2 had a low prevalence among embryos. (researchsquare.com)
  • To determine whether GATA4 contributes to development of either the pancreas or liver we characterized the formation of pancreatic and hepatic tissues in embryos derived from Gata4 -/- ES cells by tetraploid embryo complementation. (biomedcentral.com)
  • Analyses of pancreatic development revealed a complete absence of the ventral but not the dorsal pancreas in Gata4 -/- embryos. (biomedcentral.com)
  • Moreover, Gata6 -/- embryos displayed a similar, although less dramatic phenotype, suggesting a critical role for multiple GATA factors at the earliest stages of ventral pancreas development. (biomedcentral.com)
  • Assisted reproductive technologies (ART) such as artificial insemination (AI), cryopreservation of gametes or preimplantation embryos, superovulation, embryo transfer (ET), in vitro maturation of oocytes (IVM), in vitro fertilization (IVF), in vitro culture (IVC) of embryos, semen sexing and nuclear transfer (NT) continue to be adopted within the livestock production industries [1]. (nimss.org)
  • 2018): Genome-wide DNA methylation patterns of bovine blastocysts derived from in vivo embryos subjected to in vitro culture before, during or after embryonic genome activation. (vu-wien.ac.at)
  • The development of pre-implantation mammalian embryos in vitro is compromised, compared with those grown in vivo. (bvsalud.org)
  • When transient treatment with the histone deacetylase inhibitor trichostatin A (TSA) was tested, we observed improved nuclear remodeling in 1-cell SCNT embryos that correlated with improved rates of embryonic development at subsequent stages. (biomedcentral.com)
  • We hypothesized that the reprogramming of gene expression in NT embryos is independent of somatic histone deacetylation, and that hyperacetylation may have a positive effect on NT embryo development. (labome.org)
  • Thus, WDR82 can be considered a key epigenetic regulation-related factor crucial in the normal growth and development of embryos. (labome.org)
  • As the embryos invade through the luminal epithelium into the stromal compartment, the stromal cells differentiate into secretory decidual cells, which support further growth and development of the implanted embryos until placentation ensues [1] - [4] . (prolekarniky.cz)
  • When transferred to mouse blastocysts, naïve hPSCs generated 0.1 to 4% human cells, of all three germ layers, including large amounts of enucleated red blood cells, suggesting a marked acceleration of hPSC development in mouse embryos. (sciencemag.org)
  • Overexpression of the antiapoptotic factor BMI1 in primed hPSCs supports limited integration of human cells in earlier embryos of mouse, rabbit, and pig ( 15 ). (sciencemag.org)
  • In vitro production (IVP) of pig embryos is a valuable tool that aids development of assisted reproductive technologies. (ksep.or.kr)
  • The low developmental competence of IVP pig embryos is partially due to the suboptimal culture conditions for embryonic development in vitro ( Funahashi and Day, 1997 ). (ksep.or.kr)
  • The nutritional and energy requirements of developing embryos are associated with biochemical and morphological changes occurring during the oocyte maturation and embryonic development. (ksep.or.kr)
  • 1994). Our previous study demonstrated that supplementation of a culture medium with glycine and alanine synergistically improved in vitro development of in vitro fertilization (IVF) embryos and also increased blastocyst cell number in the bovine ( Lee and Fukui, 1996 ). (ksep.or.kr)
  • Although promising, these results were never repeated and the development of the embryos past day 12 in utero was not assessed. (biomedcentral.com)
  • MASSIP A., VANDERZWALMEN P. and LEROY F. Effect of stage of development on survival of mouse embryos frozen-thawed rapidly. (ivf.at)
  • Multiple superovulations alter histone modifications in mouse early embryos. (abcam.com)
  • The analysis revealed a novel miRNA, miR-3099 , with potential regulatory effects on early embryogenesis, and involvement in neuronal cell differentiation/function in the brain during late embryonic and early neonatal development. (biomedcentral.com)
  • This study was subsequently conducted to examine whether superovulation treatment can preserve ultrastructural integrity and developmental competence of oocytes following oocyte activation and embryo culture. (inforang.com)
  • In conclusion, superovulation treatment may change both maturational status and functional and ultrastuctural integrity of oocytes. (inforang.com)
  • Further research is required to identify factors able to promote the maturation in vitro of oocytes, namely those obtained from prepubertal animals. (uniss.it)
  • Germ cell development is a complex process that culminates in the production of haploid gametes, i.e., spermatozoa in males and oocytes in females, which in turn unite to form a totipotent zygote that ensures embryogenesis. (rupress.org)
  • found that crowding affects a wide range of factors, including oocyte viability, complex morphology, and intimate conjunction of oocytes with cumulus/granulosa cells across the zona pellucida (Mizumachi et al . (reproduction.jp)
  • Recently, I was involved with a scientific group in Yonago, Japan in the development of ROSNI during which immature spermatozoa (spermatids) were harvested from the testes of infertile men and their nuclei were transferred into nucleated oocytes and electrofusion was applied and pregnancies were achieved. (zavos.org)
  • Galat, V. 2004-10-13 00:00:00 We studied the capacity of rabbit oocytes for electrofusion with morula blastomeres and fetal fibroblasts. (deepdyve.com)
  • GSCs not only may provide a valuable model for germ cell development and maturation but may have a role in the field of fertility preservation, with women potentially being able to store GSCs or GSC-derived oocytes from their own ovaries prior to infertility-inducing treatments. (biomedcentral.com)
  • During fetal life, mammalian oocytes initiate meiosis and become arrested at the diplotene stage of prophase I (dictyate stage). (springer.com)
  • Body weight, body fat composition, number of oocytes collected following ovarian superovulation with gonadotropins, ovarian macrophage markers and expression of genes important in folliculogenesis and steroidogenesis were quantified in the 3 groups of animals. (bvsalud.org)
  • Animals in Group 2 gained significant body weight and body mass, produced the fewest number of oocytes following superovulation, and had significant alterations in ovarian genes involved in folliculogenesis and steroidogenesis as well as genes involved in inflammation. (bvsalud.org)
  • The mammalian placenta is the organ through which respiratory gases, nutrients, and wastes are exchanged between the maternal and fetal systems. (bioone.org)
  • Manipulation of Mammalian Development , Vol. 4, Developmental Biology: A Comprehensive Synthesis ( R. B. L. Gwatkin, ed. (springer.com)
  • Several lines of evidence suggest that GATA6 has an integral role in controlling development of the mammalian liver. (asm.org)
  • Background Mammalian early embryo development requires a well-orchestrated interplay of cell signaling pathways. (researchsquare.com)
  • Abnormal mammalian preimplantation embryo development is responsible for a significant prevalence of embryo-fetal mortality in both human and domestic animal species [1-2]. (researchsquare.com)
  • This study defines integral roles for GATA factors in controlling early development of the mammalian liver and pancreas. (biomedcentral.com)
  • The mammalian Msx homeobox genes, Msx1 and Msx2 , encode transcription factors that control organogenesis and tissue interactions during embryonic development. (prolekarniky.cz)
  • Converging evidence suggests that naïve pluripotency has connection to embryonic diapause ( 16 - 18 ), which can be induced in mice by mammalian target of rapamycin (mTOR) inhibition ( 19 ). (sciencemag.org)
  • 2018. DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development, pp. 393-400). (reproduction.jp)
  • Furthermore, the authors also demonstrated that spermatozoa capable of directing embryo development to the blastocyst stage in vitro originated from rams with the least DNA damage Overall, the impact of sperm DNA damage on embryonic development depends on a balance between the extent of sperm DNA fragmentation, fragmentation type, and the oocyte's repair capacity. (reproduction.jp)
  • Possible programming pathways include changes in testicular and sperm epigenetic regulation and status, seminal plasma composition, and maternal reproductive tract responses regulating early embryo development. (pnas.org)
  • Lack of carbon air filtration impacts early embryo development. (uiowa.edu)
  • At its inception 35 years ago, the primary goal of the W171 Regional Research Project (renewed as project #s W1171, W2171 and W3171) was to establish a cooperative, multistate research group comprised of basic and applied scientists that would uncover the mysteries behind germ cell function and embryo development so that these processes could be manipulated for the improvement of livestock. (nimss.org)
  • 2020): Asynchrony between the early embryo and the reproductive tract affects subsequent embryo development in cattle. (vu-wien.ac.at)
  • 2018): Oviduct-embryo interaction in cattle: Effect of asynchrony between the embryo and the oviduct on subsequent embryo development. (vu-wien.ac.at)
  • Dynamic patterns of H3K4me3, H3K27me3, and Nanog during rabbit embryo development. (abcam.com)
  • ii] base medium co-cultured with mouse embryonic fibroblast [MEF] [n=113]. (bvsalud.org)
  • The naïve hPSCs were maintained in the same condition as mouse embryonic stem cells and exhibited high clonogenicity, rapid proliferation, mitochondrial respiration, X chromosome reactivation, DNA hypomethylation, and transcriptomes sharing similarities to those of human blastocysts. (sciencemag.org)
  • Mouse embryonic stem cells (mESCs) are in naïve pluripotency ( 1 ) that represents the ground state of development ( 2 ), from which all cells in the mouse embryo are derived ( 3 ). (sciencemag.org)
  • In contrast, the rate of blastocyst development and blastocyst morphology appear to be normal. (bioone.org)
  • Although there were no overt differences in blastocyst cell number or early placental development, reduced growth of the female labyrinth in mid gestation is likely to contribute to lower fetal weight in females at E20. (biomedcentral.com)
  • In particular, Notch role on blastocyst development and hatching remains elusive, and a complete picture of the transcription and expression patterns of Notch components during this time-period is not available. (researchsquare.com)
  • and effectors Hes1-2), and their relationship with transcription of gene markers of pluripotency and differentiation ( Sox2 , Oct4 , Klf4 , Cdx2 ) during mouse blastocyst development and hatching. (researchsquare.com)
  • Conclusion Transcription of Notch genes showed a dynamic pattern along blastocyst development and hatching. (researchsquare.com)
  • Overall, results indicate that a deregulation in Notch signaling, either by its over or under-activation, affects blastocyst development and hatching. (researchsquare.com)
  • In placental mammals, both prolactin and melatonin affect implantation, which is considered a critical point of pregnancy, since a successful pregnancy requires the development of a synchronous interaction between the endometrium and blastocyst for placental development. (bvsalud.org)
  • In contrast to PA embryonic development, the stimulating effect by the culture in T320-280 was not observed in SCNT blastocyst development (27.6% and 23.7% in T280-280 and T320-280, respectively) whereas the number of inner cell mass cells was significantly increased in T320-280 (6.1 cells vs. 9.6 cells). (ksep.or.kr)
  • 0.0563) maturation rate than superovulation. (inforang.com)
  • De nouvelles recherches seront nécessaires pour identifier les facteurs capables de stimuler la maturation in vitro des ovocytes, en particulier ceux d'animaux prépubères. (uniss.it)
  • However, such studies remain few in canids because of the lack of optimal in vitro oocyte maturation, embryo culture, and superovulation system. (reproduction.jp)
  • clomiphene citrate - (CC) A fertility drug taken orally to promote the process of follicle /egg maturation in superovulation therapy. (edu.au)
  • Development and maturation of an oocyte entail a complex and multifaceted process which has to be tightly regulated in order for the oocyte to be competent for fertilization. (biomedcentral.com)
  • The presence of glycine at high concentrations in the natural milieu implies this amino acid may have some important functions in oocyte maturation, fertilization, and early embryonic development. (ksep.or.kr)
  • Litter size in swine is controlled by several factors, including ovulation rate, uterine capacity, and fetal survivability. (advances-in-medicine.net)
  • Previous studies attempting to increase litter size in pigs by superovulation, genetic selection for ovulation rate, or embryo transfer have resulted in dramatically increased fetal numbers by Day 30 of gestation, but litter size at term was increased by only approximately 1.0 pig because of fetal loss later in gestation. (advances-in-medicine.net)
  • Following ovulation the luteinized follicle (corpus luteum) secrets progesterone which prepares the uterus for a possible pregnancy and suppresses the secretion of gonadotropins to suspend further follicular development. (goatworld.com)
  • Transvaginal ultra- sound and urinary luteinizing hormone kits (ovulation predictor) were used to determine the development of a dominant follicle.A total of 55% of patients developed an ovulatory follicle with menstrual cycle lengths less frequent than every 35 days. (stanford.edu)
  • The objective of the study was to reveal the factors associated with variable interval to ovulation following a single dose of prostaglandin F2α (PGF2) in Beetal goats. (usda.gov)
  • Moreover, nutritional factors are the most important factors because nutrition affects all aspects of the chain of reproductive events including gametogenesis, follicular development, ovulation and steroidogenesis in females. (ac.ir)
  • A fertility injection used to induce ovulation, often of more than one egg, called controlled ovarian stimulation (COS) or superovulation. (ocfertility.com)
  • In mammals, the placenta is a pregnancy-specific temporary organ that creates intimate contact between mother and foetus ensuring the maintenance of gestation and foetal well-being by the exchange of gases, nutrients and waste products [ 19 ]. (biomedcentral.com)
  • Most of the fetal and maternal complications become apparent with advancing gestation. (intechopen.com)
  • Immunohistochemical expression analysis of the human fetal lower urogenital tract [3] "We have studied the ontogeny of the developing human Male and Female urogenital tracts from 9 weeks (indifferent stage) to 16 weeks (advanced sex differentiation) of gestation by immunohistochemistry on mid-sagittal sections. (edu.au)
  • Early pregnancy loss - also known as pregnancy loss, fetal demise, miscarriage, or spontaneous abortion - is defined as a "nonviable, intrauterine pregnancy with either an empty gestational sac or a gestational sac containing an embryo or fetus without fetal heart activity prior to 12 weeks and 6 days of gestation" 1 . (nature.com)
  • The resultant mTOR signaling could trigger polyamine, insulin-like growth factor II, and nitric oxide production in blastocysts and the increased cell motility sometimes associated with synthesis of these bioactive molecules. (bioone.org)
  • Using the particular protocol they employed, these researchers were, unfortunately, not able to generate the cloned blastocysts required to create a chromosomally normal human embryonic stem cell line. (stemagen.com)
  • After fertilization, the sperm and egg genomes are remodeled into pronuclei, which appose within the oocyte cytoplasm before the first embryonic mitosis. (pnas.org)
  • The nonhuman primates occupy a unique niche among species suitable for experimental studies on fertilization and early development. (springer.com)
  • the stage of development typically reached on the fifth day after fertilization in humans. (fertilitylabinsider.com)
  • In other words, if IVF fails to result in pregnancy despite successful fertilization, embryonic development or implantation may be to blame. (ivfinfertilityclinics.com)
  • The stage in early embryonic development, typically 4-5 days following fertilization in vitro, when the embryo comprises approximately 200-300 cells and a hollow cavity termed the blastocoel. (nap.edu)
  • This zygote-specific heterochromatin organization could be observed both in maternal and paternal pronuclei after natural fertilization as well as in embryonic stem (ES) cell nuclei after nuclear transfer suggesting that this particular type of nuclear organization was essential for embryonic reprogramming and subsequent development. (biomedcentral.com)
  • An embryo that has developed to day-5 or 6 after fertilization and starts to specialize into fetal (inner cell mass) and placental (trophectoderm) cells. (ocfertility.com)
  • In some cases, it results in embryonic growth arrest but, when the development of the embryo continues, the placenta could bring adaptive responses throughout pregnancy. (biomedcentral.com)
  • Premature birth and intrauterine growth restriction are important pathologies of pregnancy associated with abnormal function of the placenta and having negative effects on the fetus, affecting primarily brain development. (umontreal.ca)
  • My laboratory is interested in understanding the role of inflammation/infection on the maternal-fetal interface, particularly the placenta, leading to these pathological pregnancies and increasing the incidence of neurodevelopmental disorders. (umontreal.ca)
  • Using in vitro/ex vivo technics on the human placenta, we investigated the impact of alarmins on the trophoblast (the main cell type of the placenta) and Hofbauer cells (placental resident fetal macrophage). (umontreal.ca)
  • Whilst no changes in placental structures were found in the immature E13 placenta, the definitive E15 placenta from female fetuses had reduced labyrinthine volume, fetal and maternal blood space volume, as well as fetal blood space surface area, when compared to placentas from males. (biomedcentral.com)
  • These data suggest sex differences in fetal growth trajectories are due at least in part, to differences in placenta growth. (biomedcentral.com)
  • Critical to normal growth and viability of the fetus is adequate development of the mature chorioallantoic placenta. (biomedcentral.com)
  • Birth in many animal species and in humans is associated with activation of hypothalamic-pituitary-adrenal function in the fetus and the increased influence of glucocorticoids on trophoblast cells of the placenta and fetal membranes. (bioone.org)
  • The trophectoderm will form the fetal part of the placenta. (fertilitylabinsider.com)
  • If these coping mechanisms are overwhelmed, improper maternal-foetal exchanges occur, potentially leading to adverse pregnancy outcomes such as abortion, preeclampsia or intra-uterine growth restriction. (biomedcentral.com)
  • In recent years, screening for aneuploidies during the first trimester has reached effectiveness of over 90% in identifying the most common aneuploidies by a combination of maternal age, fetal nuchal translucency, as well as analysis of free beta-hCG and pregnancy-associated plasma protein A (PAPP-A) [ 2 ]. (intechopen.com)
  • We suggest that in ovine pregnancy glucocorticoids directly increase fetal placental prostaglandin production, and indirectly increase prostaglandin production by maternal uterine tissues through the stimulation of placental estradiol synthesis. (bioone.org)
  • However, a high-order pregnancy is a complication for which the doctor can perform a selective fetal reduction, in order to reduce this to twins. (drmalpani.com)
  • Transvaginal ultrasound (TVUS) provides high-resolution images, low inter-observer variability with high reliability, and is typically used to make diagnosis of intrauterine pregnancy and to follow up with its development 9 . (nature.com)
  • Thus, it is clear that treatment with prolactin or melatonin interferes with the processes responsible for the development and maintenance of pregnancy. (bvsalud.org)
  • Loss of a pregnancy after it has developed to a stage where a fetal structure is detectable on ultrasound. (ocfertility.com)
  • Extensive research over the past decade, using genetically altered mutant mouse models, has identified several factors that critically regulate uterine function in the preimplantation or postimplantation phases of pregnancy [5] - [11] . (prolekarniky.cz)
  • A blood test performed to evaluate the development of the fetus and to look for fetal abnormalities. (tripod.com)
  • Although relatively uncommon, eating disorders can negatively affect menstruation, fertility, and maternal and fetal well-being. (ivfinfertilityclinics.com)
  • Male infertility research is largely in the hands of a small cohort of academic investigators backed by programs such as those at the U.S.'s Eunice Kennedy Shriver National Institute of Child Health and Human Development and REPROTRAIN, a program funded by the European Commission to prepare researchers to study male reproductive biology. (asbmb.org)
  • In recent years, the pharmaceutical players in contraceptive and fertility treatments, such as Schering Plough, Organon and Wyeth, have withdrawn from reproductive biology research and development. (asbmb.org)
  • Among all the reproductive technologies, cloning with embryonic and foetal cells has progressed dramatically in sheep and nuclear transfer has been used to produce transgenic animals as an alternative to pronuclear injection. (uniss.it)
  • In most cases, however, such efforts were in vain because of an arrest of embryonic development, failure of reproductive function, manifestation of metabolic disorders, etc. in animals carrying hGH gene, and unfortunately no promising results were obtained so far. (nii.ac.jp)
  • Reproductive performance of livestock is determined by four factors containing genetic merit, physical environment, management and nutrition. (ac.ir)
  • Nutritional factors are perhaps the most crucial ones, in terms of their direct effects on reproductive performance. (ac.ir)
  • The leading cause of death among women of reproductive age is HIV/AIDS which is due to biological factors and limitation of women's knowledge about HIV and unsafe sex. (conferenceseries.com)
  • With the development of assisted reproductive technology (ART), diseases believed to be caused by ART have begun to be identified as imprinted disease. (springeropen.com)
  • These results indicate that perinatal exposure to a diet elevated in AGEs causes deficits in perinatal growth, pubertal onset, and reproductive organ development in female mice. (bvsalud.org)
  • Regulation of Human Fetal Ovarian Germ Cell Development. (ssr.org)
  • The Tudor domain-containing proteins (TDRDs) are an evolutionarily conserved family of proteins involved in germ cell development. (rupress.org)
  • The uterus (15-20 cm long in the non-pregnant state) is the site of fetal implantation and consists of two uterine horns with a common uterine body. (goatworld.com)
  • Rather, it regulates development of trophoblast protrusive activity and may act as a developmental checkpoint for implantation. (bioone.org)
  • However, the role of Notch in embryonic pre-implantation development is controversial. (researchsquare.com)
  • For example, if sperm and egg quality are normal, then the conception issue may be rooted at the embryonic or implantation level. (ivfinfertilityclinics.com)
  • Progesterone stimulates the endometrial secretion of several molecules involved in conceptus growth and development during the peri-implantation period. (usda.gov)
  • We observed overlapping expression of these factors in uterine epithelial and stromal compartments of pregnant mice prior to embryo implantation. (prolekarniky.cz)
  • Successful implantation is dependent on a timely progression of a series of biological events during which the embryo undergoes functional interactions with the uterus prepared by the maternal factors [1] - [4] . (prolekarniky.cz)
  • The unusually rapid growth and development of the cloned goat may have resulted from SCNT-associated epigenetic reprogramming involving telomere shortening. (koreascience.or.kr)
  • Then in a subsequent series of follow-up studies, they were able to show that factors within the egg had apparently completely erased the epigenetic fingerprint that makes a cell a fibroblast. (stemagen.com)
  • Through a transcriptome analysis, we detected a different pattern of mRNA transcription in the liver at birth comparing male vs female and microsomic vs normal mice, noting some modifications in epigenetic regulatory genes in females and modifications in some growth factor genes in males. (biomedcentral.com)
  • 1) neonatal microsomia is not always a risk factor for adult metabolic syndrome, (2) neonatal non-genetic microsomia displays changes in the expression of important epigenetic genes and changes in liver mRNA transcription profile at birth, exaggerating sexual dimorphism, and (3) random preimplantation phenotypic variability could partially explain body birth weight variation in isogenic lines. (biomedcentral.com)
  • Whereas the genome-wide methylation patterns and levels of differentiated somatic lineages remain largely constant, very dynamic changes have been reported to occur in the preimplantation embryo in association with the formation of pluripotent embryonic nuclei. (pnas.org)
  • In vivo footprinting analyses of pluripotent embryonic gut endoderm revealed that GATA4 bound the Albumin ( Alb1 ) enhancer prior to the onset of albumin expression in the primary liver bud, implying a role for GATA4 in regulating the onset of hepatic mRNA expression ( 2 , 3 , 5 , 7 , 15 ). (asm.org)
  • The association between poor paternal diet, perturbed embryonic development, and adult offspring ill health represents a new focus for the Developmental Origins of Health and Disease hypothesis. (pnas.org)
  • Notch is a major regulatory pathway involved in cell-fate determination in embryonic and adult scenarios. (researchsquare.com)
  • Research from as long ago as 2006 has shown that other pluripotent cells (e.g. embryonic stem cells) are also able to reprogram adult somatic cells when they are fused together. (stemagen.com)
  • Compared to perinatal exposure to the L-AGE diet, perinatal exposure to the H-AGE diet caused lower body weight at birth, and adult offspring exhibited delayed growth, lower serum leptin and adiponectin levels, delayed vaginal opening, irregular oestrous cyclicity, arrested follicular development and significant alterations in the expression of genes involved in folliculogenesis (Amh and Amhr2) and steroidogenesis (Cyp19a1). (bvsalud.org)
  • Molecular and genetic analyses have suggested that the GATA factors may also act to control hepatogenesis ( 2 , 36 , 38 , 39 , 44 , 46 , 47 ). (asm.org)
  • Genetic relationship between placental and fetal weights and markers of the metabolic syndrome in reat recombinant inbred strains. (rns4u.com)
  • Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia. (rns4u.com)
  • It is believed that the main factors of low prenatal growth in mammals are genetic and environmental. (biomedcentral.com)
  • Bardet-Biedl syndrome - (BBS) is an abnormality with triallelic inheritance and is characterized by a rangne of multisystem abnormalities (cone-rod dystrophy, truncal obesity, postaxial polydactyly, cognitive impairment, neural development, male hypogonadotrophic hypogonadism, complex female genitourinary malformations, and renal dysfunction). (edu.au)
  • Importantly its sex chromosome dependence, late embryonic/fetal differential development, complex morphogenic changes, long time-course, hormonal sensitivity and hormonal influences make it a system prone to many different abnormalities. (edu.au)
  • Potential role of maternal serum microRNAs as a biomarker for fetal congenital heart defects. (labome.org)
  • Therefore, we postulate that these maternal serum miRNAs may be a potential biomarker for fetal CHD. (labome.org)
  • Endometrial glands secrete molecules hypothesized to support conceptus growth and development. (biomedsearch.com)
  • Day 14 UGKO uteri that were devoid of endometrial glands did not support normal conceptus development and contained either no conceptuses or growth-retarded tubular conceptuses. (biomedsearch.com)
  • Amongst the different mechanisms, epigenetics, especially thanks to a finely tuned network of imprinted genes stimulated by foetal signals, may modify nutrient transfer, placental growth and vascularization. (biomedcentral.com)
  • Nadeau-Vallée M, Obari D, Quiniou C, Olson D, Girard S , Chemtob S. A critical role of interleukin-1 in preterm labor, Cytokine and Growth Factor Reviews , In press. (umontreal.ca)
  • To our knowledge, this is the first case in which a cloned animal born with a normal weight exhibited accelerated growth and development. (koreascience.or.kr)
  • By applying this principle, a number of disorders could be prevented or treated with better outcome: fetal aneuploidy and anomalies, miscarriage, stillbirth, preterm delivery, preterm premature rupture of membranes, preeclampsia, and intrauterine growth restriction [ 1 ]. (intechopen.com)
  • DNA methylation also plays an important role in allele-specific repression at imprinted gene loci, regulating such processes as fetal growth and development as well as X inactivation (reviewed in refs. (pnas.org)
  • Thus, transplacental exchange provides for all the metabolic demands of fetal growth and development. (bioone.org)
  • In fact, increased uterine vascular resistance and reduced uterine blood flow can be used as predictors of high risk pregnancies and are associated with fetal growth retardation. (bioone.org)
  • Recent studies, including gene knockouts in mice, indicate that the vascular endothelial growth factors represent a major class of placental angiogenic factors. (bioone.org)
  • Other angiogenic factors, such as the fibroblast growth factors or perhaps the angiopoietins, also may play important roles in placental vascularization. (bioone.org)
  • Anti-Mullerian Hormone ( AMH , Müllerian Inhibiting Substance, MIS, Müllerian Inhibiting Factor, MIF) A secreted glycoprotein factor (transforming growth factor-beta, TGF-beta superfamily) that regulates gonadal and genital tract development. (edu.au)
  • Bmp4 is an essential growth factor for the initiation of genital tubercle (GT) outgrowth [1] "The external genitalia are appendage organs outgrowing from the posterior body trunk. (edu.au)
  • Several growth factors such as fibroblast growth factor (FGF), Wnt and Sonic hedgehog ( Shh ) are essential for the GT outgrowth. (edu.au)
  • Hence, current results indicate that Bmp4 is an essential growth factor for the initiation of GT outgrowth independent of Shh signaling. (edu.au)
  • In mice, hepatic development begins at the six- to eight-somite stage of embryogenesis (E8.0) in response to inductive signals from the heart and septum transversum, including fibroblast growth factors and bone morphogenetic proteins, as well as the presence of endothelial cells ( 9 , 15 , 17 , 24 , 40 , 45 ). (asm.org)
  • In addition to growth factors, gene-targeting studies have implicated several transcription factors in controlling distinct aspects of hepatogenesis ( 8 - 10 ). (asm.org)
  • Myostatin (MSTN) can negatively regulate the growth and development of skeletal muscle. (bioscirep.org)
  • It is a member of the transforming growth factor β (TGF-β) superfamily of growth and differentiation factors [ 1 , 2 ]. (bioscirep.org)
  • Increased canonical Wnt signaling in the stromal cells activated β-catenin, stimulating the production of a subset of fibroblast growth factors (FGFs) in these cells. (prolekarniky.cz)
  • Recent studies in our laboratory indicated that a subset of fibroblast growth factors (FGFs) produced by the stromal cells act in a paracrine manner to promote luminal epithelial proliferation. (prolekarniky.cz)
  • Effects of gonadotropins and insulin-like growth factor-I. (ubc.ca)
  • Effects of follicle-stimulating hormone (FSH), luteinizing hormone (LH), insulin-like growth factor-I (IGF-I), and insulin-like growth factor-II (IGF-II) on steroid production by bovine granulosa cells were determined. (ubc.ca)
  • Insulin-like growth factor-I increased P₄ production from all categories of follicles. (ubc.ca)
  • Insulin-like growth factor-II inhibited P₄ production by granulosa cells from medium and large follicles (p (ubc.ca)
  • The bovine granulosa cell culture system developed in the present study can be used for the further studying the effects of hormones, growth factors and their interactions on bovine granulosa cells. (ubc.ca)
  • 2017. Nanotechnology-based selection of boar spermatozoa: growth development and health assessments of produced offspring. (msstate.edu)
  • In mice, renin expression is detected by in situ hybridization at embryonic day E14 in the earliest observable intrarenal arteries and is associated with the newly formed branches of the renal arterial tree ( 24 ). (physiology.org)
  • Superovulation in B6D2F1 mice (age 8-10 wk) was induced by injection of 5 international units of equine chorionic gonadotropin and 5 international units of human chorionic gonadotropin 48 h later. (pnas.org)
  • WDR82, a key epigenetics-related factor, plays a crucial role in normal early embryonic development in mice. (labome.org)
  • Transcription Factor binding to IGHM Enhancer 3 (TFE3), a transcription factor linking nutrient-sensing, stress, and autophagy ( 20 , 21 ), plays a critical role in maintaining naïve pluripotency in mice ( 22 ). (sciencemag.org)
  • The development of the follicle is under the control of gonadotropins (follicle stimulating hormone - FSH and luteinizing hormone - LH) released by the pituitary gland. (goatworld.com)
  • The cumulus cells function to nurture the egg and regulate its development in the follicle of the ovary. (fertilitylabinsider.com)
  • Granulosa cells (GCs) are essential components of follicles and play a role in regulating follicle development. (bvsalud.org)
  • Once the growing follicle reaches the preantral stage, however, appropriate levels of gonadotropins, particularly follicle stimulating hormone (FSH) are required for development to the preovulatory stage. (contemporaryobgyn.net)
  • While many of the techniques described in earlier editions of this manual have been relegated to core facilities, advances in DNA sequencing techniques and genome analysis have opened new avenues of research and developments. (cshlpress.com)
  • This study provides the first insight into genome wide miRNA expression, their role in regulation of trophoblast differentiation as well as abnormal placental development in Somatic Cell Nuclear Transfer pregnancies to pave the way to improve the efficiency of cloning by nuclear transfer. (beds.ac.uk)
  • Progress in this area should be expected by an appropriated control of follicular development with gonadotropin-releasing hormone (GnRH) agonist or antagonist prior to gonadotrophin administration. (uniss.it)
  • Follicular development can be monitored by serial hormonal measurements (oestradiol, LH, progesterone) and by ultrasonography (12) (18) . (contemporaryobgyn.net)
  • Follicular diameters, alone, in addition, to other factors were analyzed by student's t-test and chi-square test, respectively. (bvsalud.org)
  • Ovarian fragmentation induces nuclear YAP1 accumulation and increased follicular development. (biomedcentral.com)
  • Although GATA6 is expressed in multiple tissues that impact development of the liver, including the heart, septum transversum mesenchyme, and vasculature, all are relatively unaffected by loss of GATA6, which is consistent with a cell-autonomous requirement for GATA6 during hepatogenesis. (asm.org)
  • Embryonic erythropoiesis in vertebrates is characterized by development of pluripotent hematopoietic stem cells from embryonic mesoderm and formation of blood islands in the yolk sac. (advances-in-medicine.net)
  • In contrast, human embryonic stem cells (hESCs) ( 4 ) are in a primed state of pluripotency with many different properties ( 5 ). (sciencemag.org)
  • In the mouse, the germ cell lineage in a newly developing embryo arises as primordial germ cells (PGCs) that segregate from somatic lineages and establish at around embryonic day 7.0 (E7.0) in the posterior extraembryonic mesoderm ( Saitou and Yamaji, 2010 ). (rupress.org)
  • This research demonstrated the capability of proteins and other factors remaining in the egg after the nucleus is removed are capable of reprogramming somatic cells back to their 'embryonic state. (stemagen.com)
  • The aim of this study was to determine the effects of glycine or/and alanine in medium with two different osmolarities (280 and 320 mOsm) during IVC on embryonic development after parthenogenesis (PA) and somatic cell nuclear transfer (SCNT) in pigs. (ksep.or.kr)
  • anorchia - (embryonic testicular regression, vanishing testis syndrome) Clinical term for the absence of testes in a 46,XY individual with a male phenotype. (edu.au)
  • Herr has developed two commercial home tests for male infertility, Sperm Check Fertility and Sperm Check Vasectomy, using biomarkers that are unique to the final stage of sperm development in the testes. (asbmb.org)
  • Can Male Fertility Be Improved Prior to Assisted Reproduction through The Control of Uncommonly Considered Factors? (journaldatabase.info)
  • They proliferate, migrate through the hindgut endoderm, and colonize the embryonic gonads at ∼E10.5 ( Richardson and Lehmann, 2010 ). (rupress.org)
  • Murine genital tubercle (GT), anlage of external genitalia, initiates its outgrowth from embryonic day (E) E10.5 as a bud structure. (edu.au)
  • Sexual dimorphism in placental development is most often examined following prenatal stressors [ 6 , 7 ], but inherent differences have rarely been investigated. (biomedcentral.com)
  • Cyclic adenosine monophosphate response element modulator (CREM) and TRF2, key transcription factors for spermiogenesis, are expressed in Tdrd5 -deficient round spermatids, but their targets, including Prm1 / Prm2 / Tnp1 , are severely down-regulated, which indicates the importance of IMC/CB-mediated regulation for postmeiotic gene expression. (rupress.org)
  • Our work focuses on non-pathogenic inflammatory mediators (namely alarmins or damage-associated molecular pattern, DAMPs), the central goal being to determine their role at the maternal-fetal interface and the long-term impact on child development following prenatal exposure to alarmins and inflammation. (umontreal.ca)
  • Hallmarks of fetal development in swine at this time include organogenesis and sexual differentiation. (advances-in-medicine.net)
  • La production d'embryons, après superovulation, est limitée par la réponse non reproductible au traitement hormonal. (uniss.it)
  • Una segunda categoría puede describirse como aquellos factores biológicos, que incluyen, entre muchos otros, el estímulo hormonal previo a la punción folícular, el momento en que se lleva a cabo el procedimiento en relación con el estado puntual del ciclo estral, la edad, la raza y la condición fisiológica de la donante. (docplayer.net)
  • hormonal superovulation. (deepdyve.com)
  • In addition, recent observations suggest that these angiogenic factors interact with the local vasodilator nitric oxide to coordinate placental angiogenesis and blood flow. (bioone.org)
  • Fetal adrenal and gonadal arteries also expressed GFP. (physiology.org)
  • In addition, other reported fetal sites of renin expression are adrenal gland, the testes ( 16 ), and gonadal arteries ( 18 ), as well as placental tissue ( 22 , 25 ). (physiology.org)
  • Such differences of sex development (DSDs) are congenital conditions in which chromosomal, gonadal, or anatomical sex is atypical. (edu.au)
  • The GATA family of zinc finger transcription factors currently consists of six members in mammals ( 34 ). (asm.org)
  • Jianjun Z, Yali H, Zhiqun W, Mingming Z, Xia Z. Imbalance of T-cell transcription factors contributes to the Th1 type immunity predominant in pre-eclampsia. (labome.org)
  • Transcription factors play a major role in the remodeling of the chromatin nucleosomal structure in regions that include gene promoters, and histone acetyl transferases (HATs) are essential in this remodeling ( 33 , 70 ). (asm.org)
  • B-Myc, a proximal caput epididymal protein, is dependent on androgens and testicular factors for exp. (biomedsearch.com)
  • Stabilization prior to injection Compression of the oocyte during initial penetration into the ooplasm Intracytoplasmic sperm injection (ICSI) with ejaculated, epididymal or testicular spermatozoa was first successful in 1992 and has since become the widely accepted treatment for couples with severe male-factor infertility. (slideplayer.com)
  • GATA4, a zinc finger transcription factor, is strongly expressed in these endodermal domains and molecular analyses have implicated GATA4 in potentiating liver gene expression during the onset of hepatogenesis. (biomedcentral.com)