Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation.
The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.
A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
Apparatus that provides mechanical circulatory support during open-heart surgery, by passing the heart to facilitate surgery on the organ. The basic function of the machine is to oxygenate the body's venous supply of blood and then pump it back into the arterial system. The machine also provides intracardiac suction, filtration, and temperature control. Some of the more important components of these machines include pumps, oxygenators, temperature regulators, and filters. (UMDNS, 1999)
Surgery performed on the heart.
Devices in which blood and oxygen are separated by a semipermeable membrane, generally of Teflon or polypropylene, across which gas exchange occurs. The membrane may be arranged as a series of parallel plates or as a number of hollow fibers; in the latter arrangement, the blood may flow inside the fibers, which are surrounded by gas, or the blood may flow outside the fibers and the gas inside the fibers. (Dorland, 28th ed)
A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).
Application of heat to correct hypothermia, accidental or induced.
Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA 90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
A group of three different alpha chains (CD11a, CD11b, CD11c) that are associated with an invariant CD18 beta chain (ANTIGENS, CD18). The three resulting leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE ADHESION) are LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MACROPHAGE-1 ANTIGEN; and ANTIGEN, P150,95.
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
A surgical specialty concerned with diagnosis and treatment of disorders of the heart, lungs, and esophagus. Two major types of thoracic surgery are classified as pulmonary and cardiovascular.
The period following a surgical operation.
Application of a life support system that circulates the blood through an oxygenating system, which may consist of a pump, a membrane oxygenator, and a heat exchanger. Examples of its use are to assist victims of smoke inhalation injury, respiratory failure, and cardiac failure.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
Surgical incision into the chest wall.
Elements of limited time intervals, contributing to particular results or situations.
The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
Surgical insertion of synthetic material to repair injured or diseased heart valves.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Methods of creating machines and devices.
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.
Persons or entities that introduce a novel composition, device, or process, as well as improvements thereof.
Devices which mechanically oxygenate venous blood extracorporeally. They are used in combination with one or more pumps for maintaining circulation during open heart surgery and for assisting the circulation in patients seriously ill with some cardiac and pulmonary disorders. (UMDNS, 1999)
Exclusive legal rights or privileges applied to inventions, plants, etc.
A genus of the family HYLOBATIDAE consisting of six species. The members of this genus inhabit rain forests in southeast Asia. They are arboreal and differ from other anthropoids in the great length of their arms and very slender bodies and limbs. Their major means of locomotion is by swinging from branch to branch by their arms. Hylobates means dweller in the trees. Some authors refer to Symphalangus and Nomascus as Hylobates. The six genera include: H. concolor (crested or black gibbon), H. hoolock (Hoolock gibbon), H. klossii (Kloss's gibbon; dwarf siamang), H. lar (common gibbon), H. pileatus (pileated gibbon), and H. syndactylus (siamang). H. lar is also known as H. agilis (lar gibbon), H. moloch (agile gibbon), and H. muelleri (silvery gibbon).
The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.
Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.
Health planning and resources development agencies which function in each health service area of the United States (PL 93-641).
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.
The specialty related to the performance of techniques in clinical pathology such as those in hematology, microbiology, and other general clinical laboratory applications.
The transference of a heart from one human or animal to another.
The administrative procedures involved with acquiring TISSUES or organs for TRANSPLANTATION through various programs, systems, or organizations. These procedures include obtaining consent from TISSUE DONORS and arranging for transportation of donated tissues and organs, after TISSUE HARVESTING, to HOSPITALS for processing and transplantation.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
Pathological processes of the snail-like structure (COCHLEA) of the inner ear (LABYRINTH) which can involve its nervous tissue, blood vessels, or fluid (ENDOLYMPH).
The internal resistance of a material to moving some parts of it parallel to a fixed plane, in contrast to stretching (TENSILE STRENGTH) or compression (COMPRESSIVE STRENGTH). Ionic crystals are brittle because, when subjected to shear, ions of the same charge are brought next to each other, which causes repulsion.

Validation of haemodialysis recirculation and access blood flow measured by thermodilution. (1/380)

BACKGROUND: Recirculation (R) and access blood flow (Qac) measurements are considered useful indicators of adequate delivery of haemodialysis. It was the purpose of this study to compare measurements of R and Qac obtained by two different techniques which are based on the same principle of indicator dilution, but which differ because of the characteristics of the injection and detection of the different indicators used. METHODS: Recirculation measured by a thermal dilution technique using temperature sensors (BTM, Fresenius Medical Care) was compared with recirculation measured by a validated saline dilution technique using ultrasonic transducers placed on arterial and venous segments of the extracorporeal circulation (HDM, Transonic Systems, Inc.). Calculated access flows were compared by Bland Altman analysis. Data are given as mean +/- SD. RESULTS: A total of 104 measurements obtained in 52 treatments (17 patients, 18 accesses) were compared. Recirculation measured with correct placement of blood lines and corrected for the effect of cardiopulmonary recirculation using the 'double recirculation technique' was -0.02 +/- 0.14% by the BTM technique and not different from the 0% measured by the HDM technique. Recirculation measured with reversed placement of blood lines and corrected for the effect of cardiopulmonary recirculation was 19.66 +/- 10.77% measured by the BTM technique compared with 20.87 +/- 11.64% measured by the HDM technique. The difference between techniques was small (-1.21 +/- 2.44%) albeit significant. Access flow calculated from BTM recirculation was 1328 +/- 627 ml/min compared with 1390 +/- 657 ml/min calculated by the HDM technique. There was no bias between techniques. CONCLUSION: BTM thermodilution yields results which are consistent with the HDM ultrasound dilution technique with regard to both recirculation and access flow measurement.  (+info)

Extracorporeal rheopheresis in the treatment of acute ischemic stroke: A randomized pilot study. (2/380)

BACKGROUND AND PURPOSE: Extracorporeal rheopheresis is a safe method to optimize hemorheology. Our aim was to determine whether treatment with extracorporeal rheopheresis in patients with acute ischemic hemispheric stroke improves cerebral perfusion as assessed with serial 99mTc-ethyl-cysteinate-dimer single-photon emission CT (99mTc-ECD SPECT). We also investigated how clinical outcome is associated with treatment and imaging results. METHODS: Thirty-three patients (mean age, 64+/-10 years) with acute ischemic hemispheric stroke were included in a prospective, randomized, parallel group pilot study. First treatment with or without extracorporeal rheopheresis took place within 12 hours after the onset of symptoms and was repeated 3 times at intervals of 24 hours. Hemorheological parameters were measured before and after each session. Each patient underwent 99mTc-ECD SPECT immediately before treatment, 6 to 8 hours after treatment, and after 5 days. A semiquantitative SPECT graded scale was used to measure depth and extent of activity deficits and thus to quantify the perfusion deficit. RESULTS: Seventeen patients were actively treated with extracorporeal rheopheresis, and 16 patients did not receive extracorporeal rheopheresis. After 3 months, no differences were found in the functional or neurological outcome. Despite a rapid, sustained decrease of plasma viscosity and erythrocyte aggregation in the rheopheresis group, there was no significant difference in the SPECT graded scale after therapy between the 2 groups. Patients with early reperfusion (decrease in the SPECT graded scale >25% 6 to 8 hours after therapy compared with the baseline examination) experienced a better functional outcome (Modified Rankin Scale) after 3 months compared with patients without reperfusion (P=0.04). CONCLUSIONS: Since quantitative flow mapping and clinical follow-up did not reveal any differences between patients who were treated with extracorporeal rheopheresis and controls, it appears very unlikely that extracorporeal rheopheresis enhances reperfusion after acute cerebral ischemia.  (+info)

The effects of extracorporeal whole body hyperthermia on the functional and phenotypic features of canine peripheral blood mononuclear cells (PBMC). (3/380)

In this study the effect of transient 42.3 degrees C whole body hyperthermia (WBH) on the distribution of PBMC phenotypes and in vitro blastogenic responsiveness was determined in dogs. Hyperthermia (n = 6) was induced by heating venous blood during extracorporeal circulation (venous perfusion WBH); perfused non-heated dogs (n = 4) were used as controls. Both euthermic and hyperthermic perfusion produced transient lymphopenia which normalized in controls after perfusion but persisted in hyperthermic animals throughout the 8-day post-perfusion observation interval. The transient lymphopenia in control dogs was non-selective. In contrast, WBH-associated lymphopenia was selective, in that CD5+ T lymphocytes were more sensitive to hyperthermia than sIg+ B cells and, within the T cell compartment, suppressor (CD8+) cells were more sensitive to hyperthermic stress than helper (CD4+) lymphocytes. Functional analyses showed that WBH caused persistent suppression of PBMC blastogenesis in response to T cell phytomitogens. Increased plasma cortisol levels were correlated to peak lymphopenia and hyporesponsiveness to phytomitogens. Despite these alterations, high grade WBH was well tolerated and there was no evidence of opportunistic infection.  (+info)

Coating of extracorporeal circuit with heparin does not prevent sequestration of propofol in vitro. (4/380)

Propofol is sequestered in extracorporeal circuits, but the factors responsible for the phenomenon are mostly unknown. We have compared two extracorporeal circuits (oxygenators, reservoirs and tubings) coated with heparin with two corresponding uncoated circuits for their capacity to sequester propofol in vitro. Three experiments were conducted with each circuit. The circuit was primed with a mixture of Ringer's acetate solution and whole blood, and the study conditions (pump flow, temperature, pH) were standardized. Propofol was added to the solution to achieve a concentration of 2 micrograms ml-1. These studies were followed with concentrations of 10- and 100-fold to assess possible saturation of propofol binding. Serial samples were obtained from the circulating solution for measurement of propofol concentration. Propofol concentrations decreased to 22-32% of the initial predicted concentration of 2 micrograms ml-1 in the circuits (no significant difference between circuits). With greater concentrations, the circuits did not become saturated with propofol, even with the highest predicted concentration of 200 micrograms ml-1. We conclude that propofol was sequestered in extracorporeal circuits in vitro, irrespective of coating the circuit with heparin.  (+info)

Metabolism of radioiodinated fatty acid analogs in ischemic and hypoxic canine myocardium. (5/380)

Myocardial metabolism of 17-[123I]-iodoheptadecanoic acid (IHDA), 15-(p-[131I]-iodophenyl)pentadecanoic acid (pIPPA) and 15-(p-[125I]-iodophenyl)-3,3-dimethylpentadecanoic acid (DMIPP) was assessed during ischemia and hypoxia. The simultaneous investigation allowed us to evaluate differences in metabolic handling of these three fatty acids. METHODS: In 17 open-chest dogs, the left ascending coronary artery was cannulated and extracorporeal bypass (ECB) perfused. In 3 dogs, ECB flow was kept normal, and these control experiments showed that kinetics of the radioiodinated fatty acids were not affected by the ECB technique itself. In 9 dogs, ECB flow was reduced to one third (ischemia), and in 5 dogs, the ECB area was perfused with venous blood and was kept at control values (hypoxia). After simultaneous intravenous injection of IHDA, pIPPA and DMIPP, seven paired biopsy specimens from the native and ECB-perfused myocardium were taken over an assay period of 35 min. Total activity and the distribution in the aqueous phase and lipid fractions were determined, and time-activity curves were constructed. RESULTS: In ischemic (Is) but not in hypoxic (Hy) myocardium, peak total activity of IHDA, pIPPA and DMIPP decreased significantly versus normal (N) myocardium (IHDA: N = 700 +/- 267 versus Is = 335 +/- 158 dpm/mg/mCi; pIPPA: N = 988 +/- 318 versus Is = 438 +/- 180 dpm/mg/mCi; DMIPP: N = 352 +/- 146 versus Is = 179 +/- 82 dpm/mg/mCi; all P values < 0.001). The relative decrease was similar for IHDA, pIPPA or DMIPP. Half-time values of total activity were prolonged for IHDA and pIPPA but were shortened for DMIPP in ischemic and hypoxic myocardium (IHDA: N = 22, Is = 44 and Hy = 50 min; pIPPA: N = 24, Is = 95 and Hy = 169 min; DMIPP: N = 528, Is = 409 and Hy = 115 min). The aqueous phase activity for IHDA, pIPPA and DMIPP decreased significantly versus normal myocardium in both ischemic (IHDA: N = 71% +/- 9% versus Is = 36% +/- 9%, P < 0.001; pIPPA: N = 62% +/- 10% versus Is = 25% +/- 8%, P < 0.001; DMIPP: N = 26% +/- 11% versus Is = 18% +/- 3%, P < 0.05) and hypoxic (IHDA: N = 76% +/- 8% versus Hy = 62% +/- 8%, P < 0.05; pIPPA: N = 66% +/- 8% versus Hy = 46% +/- 10%, P < 0.05; DMIPP: N = 32% +/- 6% versus Hy = 24% +/- 4%, P < 0.05) myocardium. The relative decrease was significantly highest for pIPPA and lowest for DMIPP. Incorporation into triacylglycerols increased significantly for IHDA, pIPPA and DMIPP in both ischemic and hypoxic myocardium. In normal myocardium, DMIPP was already mainly incorporated into triacylglycerols. Activity of IHDA and pIPPA in acylcarnitine increased significantly in ischemic and hypoxic myocardium. CONCLUSION: Kinetics of the radioiodinated fatty acid analogs in myocardium are altered during oxygen deprivation in a similar fashion as documented in literature for natural fatty acids. However, the changes were different between IHDA, pIPPA and DMIPP, suggesting different metabolic handling and thus reflecting different aspects of myocardial fatty acid metabolism.  (+info)

Role of C3 cleavage in monocyte activation during extracorporeal circulation. (6/380)

BACKGROUND: We previously demonstrated that inhibiting formation of terminal complement components (C5a and C5b-9) prevents platelet and neutrophil (PMN) but not monocyte activation during simulated extracorporeal circulation (SECC). This study examined whether earlier complement inhibition during SECC, blocking C3a formation, would additionally prevent monocyte activation. METHODS AND RESULTS: SECC was established by recirculating heparinized whole blood from human volunteers on a membrane oxygenator. CAB-2, a chimeric protein constructed from genes encoding the complement regulatory proteins CD46 and CD55, inactivates the C3/C5 convertases and blocks in vitro generation of C3a, C5a, and C5b-9. CAB-2 was used in 4 experiments at a final concentration of 300 micrograms/mL and 4 experiments at 30 micrograms/mL; 4 control runs used vehicle alone. Samples were assayed for C3a and C5b-9, monocyte activation (CD11b upregulation), PMN activation (CD11b upregulation and elastase release), and platelet activation (P-selectin expression and monocyte-platelet conjugate formation). CAB-2 at both doses significantly inhibited formation of C3a and C5b-9 during SECC. High-dose CAB-2 significantly blocked monocyte and PMN CD11b upregulation and PMN elastase release. CAB-2 also inhibited formation of platelet activation-dependent monocyte-platelet conjugates. CONCLUSIONS: Blockade of complement activation early in the common pathway inhibited monocyte CD11b upregulation during SECC, suggesting that early complement components contribute most to monocyte activation during SECC. As expected, PMN and platelet activation were blocked by terminal complement inhibition. This investigation further elucidates the relation between complement and blood cell activation during simulated cardiopulmonary bypass.  (+info)

Nitric oxide does not modulate the increases in blood flow, O2 consumption, or contractility during CaCl2 administration in canine hearts. (7/380)

OBJECTIVE: Endothelium-derived nitric oxide (EDNO) has been shown to have vascular, metabolic, and contractile effects in the heart. We evaluated these effects during intracoronary (i.c.) administration of CaCl2 in dogs. METHODS: The left anterior descending coronary artery of nine anesthetized, open-chest dogs was perfused at controlled pressure (80 mm Hg) with arterial blood. Coronary blood flow (CBF) was measured with a Doppler transducer and segmental shortening (SS) with ultrasonic crystals. Myocardial oxygen consumption (MVO2) and oxygen extraction (EO2) were calculated. Responses were assessed during i.c. infusions of CaCl2 (5, 10, 15 mg min-1) before and after administration of the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME; 300 micrograms min-1 for 15 min, i.c.). RESULTS: Before L-NAME, CaCl2 caused dose-dependent, proportional increases in SS and MVO2. Although CBF also increased, these responses were less than proportional to those in MVO2, and thus EO2 increased. L-NAME did not alter the cardiac effects of CaCl2. CONCLUSIONS: (1) CaCl2 had direct inotropic and coronary vasoconstricting effects. (2) The vasoconstricting effect impaired coupling of CBF to the augmented metabolic demands by local vasodilating mechanisms. (3) EDNO did not modulate the increases in CBF, MVO2, or SS during administration of CaCl2.  (+info)

A new method of intraoperative hydraulic impedance measurement provides valuable prognostic information about infrainguinal graft patency. (8/380)

PURPOSE: Prognostic information about graft outcome, obtained by using a new method for intraoperative measurement of vascular impedance, was evaluated. METHODS: Hydraulic impedance was measured in 136 infrainguinal bypass grafts that were entered into a multicenter trial. Seventy femoropopliteal and 66 femorocrural polytetrafluoroethylene (PTFE) grafts were used. The arterial impedance measurement involved a silicon bypass graft temporarily inserted between the proximal and distal anastomoses sites. A flowmeter probe and a pressure transducer were incorporated into the tube. The digitally stored waveforms were subjected to a fast Fourier transformation and both input (Z(x)) and characteristic (Z(0)) impedances, as well as phase relations, were computed and related to graft outcome after 3 years. RESULTS: Significant prognostic information for both popliteal and crural grafts was provided by means of the phase angle of the first harmonic. Primary and secondary patency rates for popliteal bypasses were 45% +/- 1% and 65% +/- 2% for phase angles greater than -40 degrees (n = 57) and 37% +/- 1% and 40% +/- 1% for phase angles less than -40 degrees (n = 13, p(prim ) = not significant, p(sec) < 0.01). For crural grafts, the secondary patency rates were 49% +/- 1% and 61% +/- 2% for phase angles greater than -40 degrees (n = 53) and 15% +/- 1% and 0% for phase angles less than -40 degrees (n = 13, P <.01). All crural bypass grafts with phase angles less than -40 degrees occluded within 16 months. Steady flow resistance, as well as Z(x) and Z(0), failed to indicate a significant relation to graft prognosis. CONCLUSION: This method provides reliable prognostic information regarding graft patency and opens hydraulic impedance measurement to clinical surgery. The phase lag between flow and pressure curves, as expressed by the phase angle of the first harmonic, provides significant prognostic information.  (+info)

NovTT7, 1953 J. H. GIBBON, JR, ETAL ,368 EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 1 INVENTORS .hmv bf Gaga/1.17., wrnv MA. Mamas ATTORNEY J. H. GIBBON, JR, ETAL 2,659,368 EXTRACORPOREAL CIRCULATION DEVICE Nov. 17, 1953 16 Sheets-Sheet 2 Filed May 28, 1949 Nov. 17, 1953 J. H. GIBBON, JR, ET AL I EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 5 FIG. 5 FIG? 5 mm H {R Tfll N R i m mu .T Q W MZ Mm? W my 4 m Nov. 17, 1953 J. H. GIBBON, JR., ET AL 2,559,368 EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 6 INVENTORS la/w 1% 67.950 J2, Gus/7w K17. MAI/V845 Jo/r/v A [was/Away; Kama/v a A [max/9.1;. ATTORNEY Nov. 17, 1953 J. H. GIBBON,IJR., ET AL v ,3 8 EXTRACORPOREAL CIRCULATION DEVICE (Z FIG. 22 z 14;: 1: /9.9 1 f I: I \ FIG. 51 m0 .FIG. IO NTORS FFMXM ATTORNEY Nov. 17, 1953 J. H. GIBBON, JR, ET AL EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 8 INVENTORS wrnv K4. Mum/Pas, 42 (FF/10,70 A flaws/P Jm FIG. ...
Minimal extracorporeal circulation (MECC) systems have been designed in order to reduce dramatically the side-effects of conventional extracorporeal circulation
BACKGROUND: The aim of the current study was to investigate the possibility of increasing the maximal tolerated dose (MTD) of a tumor-selective radiolabeled antibody when radioimmunotherapy (RIT) is combined with extracorporeal depletion of radioimmunoconjugates from the circulation. Furthermore, the authors evaluated whether this increase in dose improved the therapeutic effect on solid manifest tumors in an immunocompetent animal model. METHODS: Rats were injected with high activities/body weight of lutetium (Lu-177)- or yttrium (Y-90)-labeled antibody conjugates (monoclonal antibody tetraazacyclododecanetetraacetic acid-biotin) and subjected to removal of the conjugate from the circulation by extracorporeal affinity adsorption treatment 24 hours postinjection. Myelotoxicity was assessed by analysis of blood parameters for 12 weeks. The effect of increased doses in combination with extracorporeal affinity adsorption treatment was evaluated with respect to myelotoxicity and therapeutic effect ...
A mathematical model for blood gas and acid-base status under extracorporeal circulation was developed. This model consists of a multiple compartment model for the oxygenator, and models for arterial and venous PCO2, PO2, (including temperature- and pH-dependent shift in oxygen-binding capacity of haemoglobin), SO2, bicarbonate, base excess and pH. It was implemented in a Matlab/Simulink environment. Input parameters were oxygenator type, gas flow, FiO2, arterial pump flow, temperature, haemoglobin concentration and haematocrit. As output parameters, venous and arterial SO2, PO2, PCO2 and pH were analyzed. The model was tested by using clinical monitoring data during extracorporeal circulation of patients undergoing aorto-coronary bypass grafting as input data, and comparing the model output with the results of conventional blood gas analyses (Rapidlab 288®) retrospectively. ...
The MiECC is a closed system, without a venous reservoir, so blood will be most of the time inside the patient instead of in an open cardiotomy reservoir.. The centrifugal pump will provide an active venous drainage of the patient. The negative pressure that a centrifugal pump can create is limited at -60 mmHg. The system is used with the Califiore bloodcardioplegia technique.. The total priming volume of the system can be further reduced by autologous blood priming. The aim is a small and biocompatible system, what should lead to minimal heamodilution, reduced blood transfusion, reduced inflammatory response and reduced the amount of haemolysis.. The systemic heparinization can be reduced to 1,5 mg/kg body weight, activated clotting times of 300 sec and more are common in this technique.. The MiECC has a specific oxygenator with diffuse fibres, it is not possible to give anaesthetic gas over this system.. ...
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
Accesses that show a large (,15%) decrement over time in vascular access blood flow are associated with a high risk of thrombosis. Serial measurements of vascular access blood flow predict access thrombosis. At the moment, the measurement of access flow is time consuming, operator dependent, so that it cannot be done with every treatment. We hypothesized that extracorporeal blood flow at pressure of -200 to -260 mmHg in arterial line has correlation with access blood flow and this can be used to estimate access blood flow ...
A control deck and system for controlling and driving blood fluids through an extracorporeal blood circuit kit. In one aspect, the invention is a deck having an improved mechanism for securing a cassette in place during treatment operations. The improved deck comprises catches for slidably receiving tabs of the cassette and one or more rotating clamps for locking and securing the cassette in a loaded position. In another aspect the invention is a system for controlling and driving blood fluids having infrared communication abilities to transmit and receive real time data. In still another aspect, the invention is a system for controlling and driving blood fluids having an upright tower design that reduces the footprint of the system. In this embodiment, a centrifuge chamber is positioned in an upper portion of the system while the control deck and photoactivation chamber are located in a base portion of the system.
A kit for converting a water circulation system in a hot tub into a water purification system including a housing that can be fixedly mounted to a spa or hot tub, a chamber in the housing, an inlet fo
A filtration and circulation system for maintaining the water quality in a fish tank favorable for promoting the production and growth of fish therein and for circulating water therethrough at a rate designed to provide a high rate of water exchange in the tank. The system includes particulate, biological and activated charcoal filters serially arranged in pressurized and unpressurized sections thereof for converting or removing ammonia, waste food and excrement from the water. In addition, parallel flow paths from these filters through a protein skimmer and an ultraviolet sterilizer section, respectively, are provided for lower volume treatment of the water being circulated therethrough.
A mind map about biology - the circulation system. You can edit this mind map or create your own using our free cloud based mind map maker.
Clinical cases of normothermic extracorporeal circulation (ECC) are increasing, but the possibility of brain damage is not clear. In emergencies, the brain protective effects of mild (33-34 ) hypothermic therapy have been clearly confirmed. Natural Temperature decrease ECC was conducted in this study, hoping to obtain the advantages of both normothermic ECC and brain protection by mild hypothermia. These were 12 cases at high risk of brain damage (10 cases of brain infarction and 2 cases of severe carotid artery stenosis). In all cases, coronary artery bypass grafting operation with natural temperature decrease ECC was performed. The average laryngeal temperature dropped to 33.0 }0.3 . There was no brain infarction or ICU syndrome. Evaluation of post-operative brain condition by the patients themselves and their families was good. The possibility of natural temperature decrease ECC for high risk cases of brain damage was demonstrated ...
There is an increased oxidative stress response in patients having cardiac surgery, haemodialysis or extracorporeal membrane oxygenation that is related to poorer outcomes and increased mortality. Exposure of the patients blood to the artificial surfaces of these extracorporeal devices, coupled with inflammatory responses, hyperoxia and the pathophysiological aspects of the underlying illness itself, all contribute to this oxidative stress response. Oxidative stress occurs when there is a disruption of redox signalling and loss of control of redox balance. Ongoing oxidative stress occurring during extracorporeal circulation (ECC) results in damage to lipids, proteins and DNA and contributes to morbidity and mortality. This review discusses reactive species generation and the potential clinical consequences of oxidative stress during ECC as well as provides an overview of some current antioxidant compounds that are available to potentially mitigate the oxidative stress response.
Controversy on superiority of pulsatile versus non-pulsatile extracorporeal circulation in cardiac surgery still continues. Stroke as one of the major adverse events during cardiopulmonary bypass is, in the majority of cases, caused by mobilization o
TY - JOUR. T1 - Trillium(TM) biopassive surface. T2 - A new biocompatible treatment for extracorporeal circulation circuits. AU - Cazzaniga, A.. AU - Ranucci, M.. AU - Isgrò, G.. AU - Soro, G.. AU - De Benedetti, D.. AU - Corradi, R.. AU - Gardinali, M.. PY - 2000/5. Y1 - 2000/5. N2 - 139 patients undergoing cardiac surgery were included in a prospective, randomized trial. Patients were randomly allocated to receive cardiopulmonary bypass (CPB) with Trillium(TM) Biopassive Surface (TBS Group) coated oxygenators or conventional circuits (control group). 112 patients were studied with respect to postoperative biochemical profile; a subgroup of 27 patients was studied with respect to perioperative complement (C3a) activation. Patients in the TBS group demonstrated a significantly lower white blood cell count at the end of the operation (p=0.036) and a significantly higher platelet count the day after the operation (p=0.023) when compared to the control group. C3a was significantly higher (p=0.02) ...
Experts available for extracorporeal circulation consulting, expert witness, or analyst services for business, legal, and technical professionals.
Yesterday, the Montreal Heart Institute (MHI) advised its patients, who have undergone open-heart surgery, that there is a very small risk of bacterial infection associated from certain machines (heater-cooler devices) used during heart surgeries that require extracorporeal blood circulation. The heater-cooler devices in question, which are used in many hospitals throughout North America and Europe, may have been contaminated with the bacteria Mycobacterium chimaera during their manufacture in Germany.. At present, we have no evidence that the heater-cooler devices used at the MUHC are contaminated by the bacteria associated with the infections. No cases of such an infection have been observed in our institution following the surgeries practiced at the MUHC. All cleaning and disinfection measures recommended by the manufacturer, as well as quality controls, are in place at the MUHC and are being carefully observed.. It is important to note that transmission of the bacteria in question occurs ...
Describes a means by which cardiopulmonary bypass defoamer devices may comply with the requirement of special controls for class II devices.
材料. 当归,北耆,川芎,玉竹,红枣,党参. 可供素食. 保存方法:置于冰箱中冷藏. 净重: 75g. Additional Info. What exactly is it with the necessity to increase blood circulation or mores to the stage, what it really blood circulation exactly? Well, place in laymans terms, its this is the movement of blood with the body. A little more detail is the fact that blood circulation happens when the blood moves round the body inside what is known the blood circulation system. The blood circulation system consists of blood ships (otherwise known as arterial blood vessels), veins and capillary vessels. Our heart continuously pumps the blood through our ships before the day we die or encounter serious problems.. A few of the common signs and symptoms of poor blood circulation can include tingling sensation or numbness of either hands or ft (also known as Neuropathy) a difficulty breathing insufficient energy irregular heartbeats difficulty in remembering things and ...
Despite improvements in the biocompatibility of cardiopulmonary bypass (CPB) circuits, the activation of inflammatory systemic response can result in clinically relevant organ dysfunction. Regarding the central nervous system, prolonged hypoperfusion and microembolization during conventional CPB have been related to postoperative neurologic impairment with an incidence varying from 30% to 60%. This clinical scenario covers a spectrum from a transient subtle cognitive dysfunction to a permanent stroke. Postoperative cognitive decline (POCD) is characterized as impairment in attention, cognition, recognition, orientation, memory, and learning. It may result in prolonged hospitalization, increased morbidity and mortality, while it has an adverse impact on quality of life after surgery.. Near-infrared spectroscopy (NIRS) provides a continuous and noninvasive monitoring of regional cerebral oxygen saturation (rSO2). Recent studies have shown a significant relationship between intraoperative cerebral ...
B. False. Answers: Circulation. 1. A. True. The blood supply to the heart, efficiency of its muscle contractions, changes in rate and rhythm and increased work load all result from diving. Such stresses can be tolerated by a healthy heart, but can cause a heart attack in those with coronary problems. A person with any heart disorder should not dive unless cleared by both a cardiologist and a diving physician.. 2. B. False. The blood carries nearly as much oxygen as it can at all times. The change that takes place with exercise is in the circulation of the blood, which is increased to get oxygen to and waste products from tissues more quickly. Increased oxygen partial pressure while diving does allow more oxygen to be carried dissolved in the blood, but the benefit of this is offset by other cardiovascular changes.. 3. B. False. The carotid sinuses, located at the bifurcation of the arteries on each side of the neck, are sensors for blood pressure and provide information to the brain to control ...
Experienced cultivators understand the critical role air circulation plays in the successful growing of mushrooms. Without proper air input and distribution, there is little chance …
Under the tongue, we as a whole have a mucous film. Mucous films are thin layers of tissue that line depressions in the body and spread the outside of our organs. Some mucous layers do as the name proposes, and discharge bodily fluid-like the films that line the nose.. These films are slightly contrasted with skin, which has numerous layers. Underneath is a free layer of connective tissue, in addition to loads of little vessels. Head to a mirror and investigate your tongue, and youll see a few.. When you hold CBD under your tongue, the dynamic mixes in the arrangement are consumed through the mucous layer and enter the circulation system. Its through the circulation system that they, at that point, access your endocannabinoid framework and each other aspect of your body.read more about holding CBD under Tongue at shorturl.at/ioCHV. You wont see the entirety of the oil retain into your mucous film and vanish, however. For that to occur, youd need to hold up quite a while. After a set measure ...
WHAT IS GLUTATHIONE?. Glutathione is a cell reinforcement produced using glycine, glutamic corrosive and cysteine. Researcher view it as a standout amongst the most capable cancer prevention agents. While Glutathione is readied like any restorative or vitamin item - in a sheltered, sterile lab setting - it is made of all-characteristic amino acids that happen in nature and are advantageous to our bodies.. skin-whitening-products-in-pakista. Walnuts, avocados, tomatoes and oranges can all keep Glutathione levels high in the circulation system, however they wont really work to brighten your skin and, add to solid skin - particularly walnuts and avocados, which are additionally high in fundamental unsaturated fats.. Glutathione is by and large taken by means of intravenous injection, under the watchful supervision of a specialist dermatologist. Numerous dermatologists suggest Glutathione injections since they get 100-percent of the measurements into your circulation system. However the nature of ...
8B Respiration Releasing energy The circulation system Contents 8B Respiration Releasing energy The circulation system The breathing system Anaerobic respiration Summary activities
Methods. One hundred and nineteen -patients -were divid-ed -into 3 -groups: -group A (n=39) -had a stan-dard uncoat-ed extra-cor-po-real cir-cu-la-tion (-ECC)--set -and system-ic hep-ar-in -was giv-en in an -initial -dose of 400 IE/kg -body -weight. During -ECC acti-vat-ed clot-ting -time (-ACT) -was -kept at ≥480 sec. Group B (n=42) -had -the -same -ECC--set com-plete-ly coat-ed -with -low molec-u-lar -weight hep-ar-in, i.v. hep-ar-in -was admin-is-tered in -the -same -dose as in -group A, -ACT -was -again -kept at ≥480 -sec. Group C (n=38) -had -the -same coat-ed -ECC -set -as -group B, -but i.v. hep-ar-in -was -reduced to 150 IE/kg -and dur-ing -ECC -ACT -was maintained of ≥240 -sec ...
Polymorphonuclear leukocytes isolated as described before, were fluorescence labeled with a hydrophobic fluorescence compound (3-3-dioctadecyloxacarbocyanine perchlorate (Fluka; Sigma Aldrich) as described by Lo et al. [15] Cells at a concentration of 1 - 5 x 106cells/ml were incubated with 50 [micro sign]g/ml Fluka in HAP buffer for 10 min at 0 [degree sign]C, unbound dye was removed by three washes with HAP buffer, and labeled PMNs were resuspended in medium 199 for the adhesion assay. Fluka-labeled PMNs (10 [micro sign]l of 106cells/ml) were added to twice-washed EC monolayers. Adhesion was allowed to proceed for 15 min at 37 [degree sign]C, and unbound PMNs were removed by three washes with medium 199. Residual adherent PMNs on EC surfaces were counted manually, in a blinded manner, on an inverted microscope equipped for fluorescence using the filter IF355-550 at a magnification of x100. Values of five replicates from each circuit were averaged, and the coefficients of variation between ...
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The aim of the study was to develop and implement the most accurate methods for evaluating perinatal losses in women with extracorporal fertilization.
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership.. Click Here to Learn More ...
Very large doses of IV Bicarb, and 2-4 g IV Magnesium (as a nonspecific therapy for long QT), and IFE only if the patient is in refractory shock and cannot be put on extracorporeal circulation. Transcutaneous or transvenous pacing may be critical as well. Get the patient on extracorporeal life support as quickly as possible in cases that are likely to be refractory to medical therapy ...
A gas exchange device (100) with an extracorporeal blood circuit (102) in which a blood pump (110) is connected, with a CO2 exchange unit (112), and an oxygenator (128), whereby the gas exchange unit (112, 128) is in each case divided by a hydrophilic, water-wet membrane (114, 130) into a blood chamber (116, 132) and a gassing chamber (118, 134) which is under positive transmembrane pressure.
After years of research at ETH Zurich and University Hospital Zurich, we want to develop and bring a breakthrough blood purification approach based on highly magnetic nanoparticles to the clinics. These tiny non-toxic nanomagnets are chemically equipped with specific binding agents against harmful disease-causing substances. The nanomagnets are administered to an extracorporeal blood circuit which is connected to the patients blood stream. There they selectively bind to the harmful compounds. Before the blood flows back to the patient, the magnets are removed along with the target substances by a highly efficient magnetic separator ...
Aesculap AG (AAG): B. Braun is one of the worlds leading suppliers of healthcare products. Its four divisions orient their products and services toward different medical fields: hospital, surgery, private practice (medical care and doctors offices) and extracorporeal blood treatment. By networking the divisions knowledge and developing solutions for the healthcare system, the company transforms products and services into integrated systems. B. Brauns Aesculap Division focuses on products and services for all of the core processes in surgery. Aesculap Divisions headquarters are in Tuttlingen, Germany, where it has about 3,100 employees. Internationally, Aesculap has about 9,000 personnel, and production sites all over the world. Its product range includes surgical instruments for open or minimally invasive approaches, implants, surgical sutures, sterile container, storage, motor and navigation systems, as well as products for cardiology. Aesculap is the market leader in CT-free navigation ...
Delivers a complete range of continuous extracorporeal blood therapies with a highly versatile platform that can be customized to specific patient needs, particularly used in renal transplant therapy.. ...
Flush-mounted circulation valve Aquastrom UP-Therm Thermostatic circulation regulating valve for hydronic balancing of potable water circulation systems ...
Flush-mounted circulation valve Aquastrom UP-Therm Thermostatic circulation regulating valve for hydronic balancing of potable water circulation systems ...
From the beginning of the Thirties of the 20th century, right up to the present, many different designs for artificial circulation to be used both in experiments and in clinical practice, in cases of temporary arrest of cardiac circulation, have been described, es-pecially in connection with the use of such apparatus in cardio-vascular surgery. The expedience of using it in resuscitation however, was first suggested by Bryukhonenko and Chechulin. In order to determine the efficacy of artificial circulation in treating clinical death, Bryukhonenko devised his own perfusion apparatus, which he called an autojector.. Research carried out along these lines has confirmed the possibility of restoring respi-ration and cardiac activity by means of extracorporeal circulation in cases of clinical death due to loss of blood, drowning, asphyxia, explosive decom-pression, electric shock, and prolonged hypo-tension. It was found that use of this method to treat clinical death ensured sufficient circu-lation ...
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership.. Click Here to Learn More ...
article{f801030f-b1c8-4f04-9f4e-0159e0e77eab, abstract = {,p,S100 protein is a marker for brain damage easily analysed in blood. The serum level immediatly after termination of extracorporeal circulation (ECC) is increased and associated to age and the duration of perfusion. A prolonged residual concentration indicates cellular brain damage. The objective of this study was to ascertain if the prognosis of individual patients, with stroke following ECC, could be predicted by the S100 levels. 224 patients with an uneventful outcome constituted a reference population. Blood samples for the analysis of S100 were collected at termination of ECC (TO) and at 5, 15 and 48 hours thereafter. Eight patients with stroke following ECC were analysed. In 4, S100 levels continued to increase after ECC. The volume of brain infarctions were large and in 3 of the patients outcome was fatal. In 4 other patients with small volume brain injury S100 dropped initially, but after 5 hours the elimination slowed down, ...
Definition of vein - any of the tubes forming part of the blood circulation system of the body, carrying in most cases oxygen-depleted blood towards th
Describe the formation of lactic acid in muscles. This concerns two types of muscule cell respiration - aerobic and anaerobic. Anaerobic respiration of the cells in muscle tissue breaks down glucose to form lactic acid. This happens if the persons breathing and blood circulation systems are unable to supply sufficient oxygen to the muscle tissues to enable aerobic respiration to take place. The accumulation of lactic acid creates an oxygen-debt because the body then needs to take in more oxygen to help to remove the lactic acid build-up.
Building is treated as a time-dependent energy system, with its interactive components coupled through energy and mass flows under an environment defined in terms of sunlight, ambient air and wind and with its equipment which assist in meeting building-dwellers comfort requirements. Major components discussed are thermal mass (both interior mass and envelope mass) and their thermal capacities, building envelopes and their heat transfer resistances, room air including its circulation and heat exchange with thermal mass, and the transparent part of the envelope the glazing or windows and the solar system passing through it during the day and the heat loss during the night time. Major equipment include lighting, air circulation system, cooling and heating equipment, solar thermal panels and solar PV panels, and other equipment including integrated electric and control units. Of the comfort requirements only temperature-and-humidity and illumination are studied with the objective of creating, ...
The report demonstrates a far reaching blueprint of the whole headway heading of the market over the navigation of the figure time traverse. Unmistakable zones have been considered to give the perusers a broad perspective of the whole market condition. The commanding scene in thought with the principal affiliations and the affiliations working in the market has been incorporated and examined upon minutely. Unmistakable locales have in addition been cleared up where the market is working feasibly and the areas where the players may discover lucrative open passages later on have in like way been said in the report.. Cardiac biomarkers are the substances used to identify the hazard stratification of a patient with chest torment or suspected intense coronary disorder (ACS). These biomarkers are discharged in blood when the heart is harmed or pushed. The tests that are done by acquainting the cardiac biomarkers with the circulation system help in deciding the dangers of related heart conditions, for ...
Features: * Programmable microprocessor control(AC brushless motor) *LCD display: speed, RCF,time, conversion of RPM/RCF * External cold-rolled steel with powder coating, stainless steel centrifugal chamber and lid * Fan-forced air circulation system for fast recovery of temperature * 10 procedures of adjustable speed from levels 0 to 9 and 40 kinds of self-defining modes * Electronic lock lid and interlock safety system. Auto lock rotor system * Alarm: lid open, imbalance, over speed and rotor mounting abnormally Functions: RCF selection, quick run, automatic rotor recognition and backup. Electronic imbalance detection, dynamic electric brake system, inching function, short-spin function Model BKC-TL5LII Max. Capacity 4*750ml Max. Speed 5500rpm Max. RCF 5310xg Speed Accuracy ±20rpm Timing Range 0~99h59min59s Noise |58dB Consumption 2.5KW Power Supply AC220V, 50Hz External Size(W*D*H) mm 800*700*400 Package Size(W*D*H) mm 950*850*600 Net Weight(kg) 110 Gross Weight(kg) 135
There are many reasons for diastolic high bloodstream pressure, having a diastolic studying of more than 90mmHg and above considered high. The next are the most typical high diastolic bloodstream pressure causes.. Primary hypertension: This kind describes a condition of high bloodstream pressure that isnt related to a known disease cause, for example stiff or hardened bloodstream vessels. Its thought that primary hypertension manifests as a result of mixture of genes and ecological factors, with lots of common genetic variants being accountable for its development getting been identified. Getting isolated diastolic hypertension is mainly observed in youthful adults and isnt seen to become related to any particular cause, but are closely related to endocrine hormone imbalances or inappropriate contraction of small circulation system wall muscles.. Endocrine and kidney causes: Those hormones consists of an accumulation of glands that secrete hormones into the circulatory system. These hormones ...
There are many reasons for diastolic high bloodstream pressure, having a diastolic studying of more than 90mmHg and above considered high. The next are the most typical high diastolic bloodstream pressure causes.. Primary hypertension: This kind describes a condition of high bloodstream pressure that isnt related to a known disease cause, for example stiff or hardened bloodstream vessels. Its thought that primary hypertension manifests as a result of mixture of genes and ecological factors, with lots of common genetic variants being accountable for its development getting been identified. Getting isolated diastolic hypertension is mainly observed in youthful adults and isnt seen to become related to any particular cause, but are closely related to endocrine hormone imbalances or inappropriate contraction of small circulation system wall muscles.. Endocrine and kidney causes: Those hormones consists of an accumulation of glands that secrete hormones into the circulatory system. These hormones ...
Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura (costs for program #144113) ✔ Academic Hospital Harlaching ✔ Department of Hematology, Oncology and Palliative Medicine ✔ BookingHealth.com
Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura (costs for program #34965) ✔ Academic Hospital Nordwest ✔ Department of Oncology and Hematology ✔ BookingHealth.com
Notwithstanding adoption of the Paris Agreement on climate change, mitigation of greenhouse gas emissions appears unlikely to achieve the stated goal of limiting the mean global temperature increase to 2°C. Under many scenarios, achieving this goal would require not only vigorous mitigation efforts, but also the deployment of carbon dioxide removal technologies or solar geoengineering. While serious consideration of solar geoengineering remains fraught with peril, the use of carbon dioxide removal to remove carbon dioxide from the atmosphere and store it elsewhere appears increasingly likely. Carbon dioxide removal techniques generally would have to be undertaken on a massive scale to be effective. However, the techniques are not ready for deployment, and their widespread use would impact land use, biodiversity, food security, water availability, and other resources.. Such impacts demand greater attention to managing carbon dioxide removal efforts and their effects. The Paris Agreement does not ...
OBJECTIVES: We examined data from the International Registry of the Extracorporeal Life Support Organization to identify risk factors for mortality in pregnant and peripartum patients receiving extracorporeal membrane oxygenation.. DESIGN: Retrospective analysis.. SETTING: International Registry of Extracorporeal Life Support Organization.. PATIENTS: We collected de-identified data on all peripartum patients who needed extracorporeal membrane oxygenation between 1997 and 2017 using International Classification of Diseases, 9th and 10th Edition criteria.. INTERVENTIONS: Our primary outcome measure was in-hospital mortality. We also collected data on demographics, preextracorporeal membrane oxygenation ventilator, hemodynamic and biochemical parameters, extracorporeal membrane oxygenation mode, duration, and complications. Initial bivariate analysis assessed potential associations between survival and various preextracorporeal membrane oxygenation as well as extracorporeal membrane ...
The sea breeze/land breeze circulation system in the Los Angeles area results in transport of pollutants seaward at night followed by return of aged material inland the next day. This characteristic wind reversal pattern both increases the retention time available for the oxidation of SO_2 to form sulfates and causes individual air parcels to make multiple passes over large coastal emissions sources. As a result, the Los Angeles atmosphere exhibits high peak day and high annual mean sulfate concentrations in spite of the fact that sulfate concentrations in marine background or desert air are low. ...
The IPCC says limiting global warming to 1.5°C with no temperature overshoot will require large-scale Carbon Dioxide Removal (CDR). While emission reductions remain the first priority, simultaneously developing CDR options will be necessary to ensure they are available at the scale required to achieve global net-negative CO2 emissions in the second half of the century.. But how might this be achieved in practice?. The NewClimate Institute, with support from C2G, explores some of the options and challenges in the discussion paper Options for supporting Carbon Dioxide Removal.. Key issues include:. ...
An artificial kidney comprises an exchanger (1) having two compartments (2, 3) separated by a semipermeable membrane (4), a first compartment (2) being connected to a circuit (5, 7) for extracorporeal blood circulation, the second compartment (3) having an outlet for draining waste liquid. Means (22, 25) are provided for controlling the flow rate (QA) of a sterile solution containing a substance (A) to be perfused into the circuit (5, 7) for conveying a flow of blood outside the body, which flow rate is controlled as a function of the flow rate (QOUT) of waste liquid. This kidney makes it possible to dose a substance such as a medicine, glucose or bicarbonate, accurately into the blood of a patient undergoing treatment by hemofiltration, hemodialysis, or hemodiafiltration.
A small sized temperature sensor for measuring temperatures in the body and for measuring temperatures in an extracorporeal blood circulation circuit, wherein the possibility of electrical shock and the cost are reduced, while resolution and reliability are increased. The temperature sensor comprises a source of light, an optical fiber to receive light from the light source at one end of the optical fiber, a transducer positioned near the other end of the optical fiber, a reflection means for reflecting the irradiated light, and an arithmetic processing unit which calculates temperature based upon the reflected light measured. The transducer is made up of at least two polymers that have different temperature dependencies of refractive index and form a microphase separation structure, wherein the polymers are cured products made from a cationically polymerizable compound having epoxy groups and a radically polymerizable compound having radically unsaturated groups.
A vest system for generating cyclic fluctuations in intrathoracic pressure for use in cardiopulmonary resuscitation and non-invasive circulatory assistance. The vest is preferably provided with a two bladder inflation system. A high pressure bladder contacts the chest wall while a bias bladder is disposed between the high pressure bladder and the vest material. The bias bladder is pressurized to press the high-pressure bladder tightly against the chest wall so that cyclic inflation of the high-pressure bladder can generate large changes in intrathoracic pressure. The bias bladder is released periodically to allow the chest to expand for adequate ventilation. Air flow into and out of each bladder is controlled by sequencing large bore 3-way and 2-way solenoid valves and the rate of air flow into the high-pressure bladder is controlled by a variable resistor.
Heart bypass surgery - MedHelps Heart bypass surgery Center for Information, Symptoms, Resources, Treatments and Tools for Heart bypass surgery. Find Heart bypass surgery information, treatments for Heart bypass surgery and Heart bypass surgery symptoms.
BelSECT is the professional organisation for all Belgian perfusionists. Our aims are to develop the profession of perfusion in Belgium, to represent the members of our society towards the authorities and other private and public organisations, national and international.
Greenhouse Gas Removal (GGR) refers to an technique that removes greenhouse gases from the atmosphere through mechanical means. A more common umbrella term is Carbon Dioxide Removal (CDR), which excludes methods that remove other greenhouse gases such as methane.. ...
Analyses have been conducted to assess the capability of the Atmosphere Revitalization Subsystem to control ambient CO2 levels of the Space Station Freedom (SSF). The adequacy of the Carbon Dioxide Removal Assembly (CDRA) performance to meet design requirements has been evaluated. Analyses considered transient effects of crew location and metabolic loading on SSF Restructure configurations. The analyses consisted of computer simulations of on-orbit conditions using both supplier provided and adjusted CO2 removal performance approximations along with derived crew metabolic activities and locations. Results show that while the current performance of the CDRA will maintain CO2 levels within specifications for Man-Tended Operations, it cannot maintain the SSF atmosphere below specifications during Permanently Manned Operations. Potential design options are discussed and other relevant analyses are summarized ...
As appearead on Euractiv on 6/10/2020. The European Commissions new climate plan for 2030 increases uncertainties and gives us a rude awakening on carbon removal, writes Mark Preston.. Last month, the European Commission announced it will raise the EU 2030 target to at least -55%, also introducing the idea of a Net target (instead of an absolute one) for 2030 for the first time in the public debate. The Impact Assessment accompanying the Commissions proposal only assessed net targets, revealing that this idea has been in the making for some time, despite this not being explicit in the public consultations. We have now been faced with a rude awakening on the issue of negative emissions, long overlooked by climate policy.. The conversation on Carbon Dioxide Removal (CDR) is severely overdue, but this not only due to the new targets. In late September, the Norwegian government announced a huge plan for geological CO2 storage, a vital part of the chain for many carbon removal processes.The topic ...
According to the U.N. IPCC (October 2018), carbon dioxide removal (CDR) on a massive scale will be necessary to limit global temperature change to 1.5°C this century. Growing attention to this has focused mainly on a handful of nature-based and industrial solutions that appear to be decidedly un-urban in their footprint, operation and logistical demands.
Rickels, W.; Reith, F.; Keller, D.; Oschlies, A.; Quaas, M. F. (2018): Integrated Assessment of Carbon Dioxide Removal. In Earths Future 6 (3), pp. 565-582. DOI: …
This paper examines the broad policy frameworks that can support the development and upscaling of Carbon Dioxide Removal and, in particular, whether CDR can be supported by offsetting schemes.
Get the latest carbon dioxide removal news on Environmental XPRT, the worlds largest environmental industry marketplace and information resource.
Conclusion: Therapeutic apheresis is a progressively developing, safe, and effective treatment modality with add-on indications. Physicians should keep track of new developments on this modality to implement the appropriate indications into clinical practice. HIPPOKRATIA 2018, 22(4): 167-172.. Keywords: therapeutic apheresis, indications, ASFA. Corresponding author: Ersan Sibel, MD, Department of Nephrology of Izmir Tepecik Research and Training Hospital, University of Health Sciences, 35170, Izmir, Turkey, tel: +902324696969, fax: +902324330756, e-mail: [email protected] Introduction. Therapeutic apheresis (TA) is a general term for all extracorporeal blood purification procedures in which components of blood are separated through an extracorporeal device to treat a disease1. Depletion of the offending pathogenic constituent from the blood is attained by discarding the collected constituents (antibodies, toxins, cellular elements, etc.) and replacing it with either patients own plasma or ...
(2005) Weber et al. Biomacromolecules. To develop adsorbents for the specific removal of tumor necrosis factor-alpha (TNF) in extracorporeal blood purification, cellulose microparticles were functionalized either with a monoclonal anti-...
CytoSorb® therapy is an extracorporeal blood purification therapy designed to reduce excessive levels of inflammatory mediators such as cytokines.
CytoSorb® therapy is an extracorporeal blood purification therapy designed to reduce excessive levels of inflammatory mediators such as cytokines.
Does this patient have intrdialytic hemolysis? Grossly translucent hemolyzed blood in the extracorporeal blood line Symptoms vary depending on causes and severity Causes Mechanical High blood flow rate, single-needle dialysis, small-gauge cannula, kinked blood line, highly negative arterial pressure, offset blood pump Dialysate contamination Chloramine: dyspnea, cyanosis (methemoglobinemia, not improved by oxygen therapy), malaise, headache,…. ...
Extracorporeal circulation (ECC) methods are being increasingly used for mechanical support of respiratory and cardio-circulatory failure. Especially, cardiopulmonary bypass (CPB) during cardiovascular surgery, sustenance of the patient’s life by providing an appropriate blood flow and oxygen supply to principal organs. On the other hand, systemic inflammatory responses in patients undergoing cardiovascular surgery supported by CPB contribute significantly to CPB-associated mortality and morbidity. Our previous research showed that CPB causes a systemic inflammatory response and organ damage in a small animal CPB model. We have been studying the effects of hyperoxia and blood plasma substitute on CPB. In this review, we present a study focusing on the systemic inflammatory response during CPB, along with our findings.
In an infusion apparatus, an infusion line (4) connects a container (2) of an infusion fluid to an extracorporeal blood circuit (23). A first valve (6) closes the infusion line downstream of an infusion pump (5). An expansion chamber (9), provided with a pressure sensor (10), is arranged between the infusion pump and the first valve. A second valve (8) closes a vent line (7) of the expansion chamber. The processor closes the first valve when the container is emptied. After replacement with a new and full container, the processor restarts the pump and selectively opens the first valve or the second valve according to the increase in pressure measured in the expansion chamber.
A method for extracorporeal blood treatment which utilizes a hemodialysis machine capable of heating the dialysis fluids to 48° C., a hollow-fiber, high efficiency hemodialyzer, and a tubular heat exchanger--in addition to various probes and catheters and heated anterior and posterior blankets for the patient--to effect extracorporeal treatment without adverse effect on blood physiology and without the need for general anesthesia.
A renal treatment fluid priming method includes priming an extracorporeal circuit connected to a patient with a physiologically compatible fluid, the extracorporeal circuit including an arterial line, a venous line and blood compartment of a blood filter; and pumping from a renal treatment fluid line in communication with the blood filter (i) pulling blood from the patient through the arterial line to flush the physiologically compatible fluid through the arterial line and the blood filter compartment into the renal treatment fluid line and (ii) pulling blood from the patient through the venous line to flush the physiologically compatible fluid through the venous line and the blood filter compartment into the renal treatment fluid line, such that a greater volume of blood is pulled from the patient via (i) and (ii) than a volume of the extracorporeal circuit.
Anova, Artery, Cardiopulmonary Bypass, Coronary Artery, Coronary Artery Bypass, Coronary Artery Bypass Grafting, Extracorporeal Circulation, Hemodilution, Hemoglobin, Myocardial Revascularization, Patients, Postoperative Complications, Propensity Score, Risk, Surgery, Time
TY - JOUR. T1 - Scintigraphic assessment of alterations in cardiopulmonary haemodynamics and renal functional activity in patients with endured coronary artery bypass grafting. AU - Vesnina, Zh V.. AU - Krivonogov, N. G.. AU - Vecherskiĭ, Iu Iu. AU - Lishmanov, Iu B.. PY - 2015. Y1 - 2015. N2 - OBJECTIVE: By means of scintigraphic methods to assess alterations in cardiopulmonary haemodynamics and renal functional activity in patients with coronary artery disease (CAD) after endured coronary artery bypass grafting (CABG) performed in conditions of extracorporeal circulation (EC) and on the functioning heart.MATERIAL AND METHODS: We examined a total of 40 patients presenting with CAD (mean age 54.90±1.12 years) after endured CABG. All patients were subdivided into 2 groups: Group One consisting of 20 patients subjected to CABG performed on the beating heart with the use of myocardial stabilizer Acrobat (Study Group) and Group Two also comprising 20 patients but undergoing surgery with the ...
A patient on the operating table is exposed to numerous risks, especially if the operation is so complex, that extracorporeal circulation is required. One of the dangers is a risk of embolism by a gas bubble, which may occur in the process of blood circulation in the pump oxygenator. It is not always clear why the gas bubbles originate, but they do almost in all the cases. The smaller ones, less than 10 microns in diameter are not particularly dangerous, as they quite rapidly dissolve by themselves. As for bigger bubbles, they may plug in a vessel like a cork, thus disrupting normal blood circulation and causing very bad problems for the organism ...
POCD is a common complication following cardiac surgery and may lead to an extended stay in an intensive care unit or hospital, increased perioperative complications and mortality and a decrease in the ability of the patient to lead an independent life (2). At 1 week following cardiac surgery, the incidence of POCD is as high as 50-70 and ~40% of patients still have cognitive dysfunction at five years following surgery (37,38). CPB surgery can reduce postoperative neurocognitive ability because of hypoperfusion or low mean arterial pressure, hemodynamic instability, cerebral thrombosis, systemic inflammatory responses, anemia, hyperglycemia and extracorporeal circulation trauma (39). In the present study, a CPB rat model was successfully established and treated with a KOR agonist and then the cognitive function, inflammatory response, oxidative stress injury and apoptosis were observed. The results demonstrated that a KOR agonist could improve cognitive function and reduce brain damage in CPB ...
Technically what these scientists did is indeed very possible, its done today, with a few changes and on a live person. They just did it using a Artificial Circulation system, which are still used today in most open heart surgeries. But there are some key factors that must be met for the organs to be revived. Plus, for the time this video was made, it would have been a major medical advancement. Although the experiment seems real and not a fake, certain conditions were met for the revival to be possible, the most important being that the dogs were either perseverated, or died less than 1 hour ago. The head revival part is the most questionable part of the film, but keeping in mind that the brain must have suffered serious oxygen depravation that led to brain cell death and that the brainstem reflexes remained intact (Instincts), the dogs reaction was possible, although he probably wouldnt be able to walk or recognize things, that is, if he still had a body. So, my opinion is that some of the ...
The American Society of ExtraCorporeal Technology was founded in 1964 with the belief that members of the then-new allied health field could best serve their profession by sharing their thoughts and experiences. Steady growth was the keynote of AmSECT, as the ranks of Perfusionists expanded with the increasing demand for open-heart surgery. During the past decade, changes in lifestyle and improvements in the treatment of cardiac disease have resulted in Perfusionists facing the challenge of identifying new opportunities and expanded their practices in the areas of perioperative blood management, wound healing, ventricular assistance, and expanded uses of extracorporeal circulation.. Today AmSECT has over 2,000 members throughout the world and is dedicated to promoting the profession. The goals of the Society are diverse and include:. ...
Cancer begins with an alteration to the structure of the deoxyribonucleic acid (DNA) that is found in all human cells. This is known as a genetic mutation. The DNA provides the cells with a basic set of instructions, such as when to grow and reproduce.. The mutation in the DNA changes these instructions so that the cells carry on growing. This causes the cells to reproduce in an uncontrollable manner, producing a lump of tissue that is known as a tumour.. Most cancers grow and spread to other parts of the body through the lymphatic system. The lymphatic system is a series of glands (or nodes) that are spread throughout your body in a similar way to your blood circulation system. The lymph glands produce many of the specialised cells that are needed by your immune system.. Kidney cancer usually spreads into blood vessels that are located near to the kidney or the adrenal gland. The adrenal gland is an organ that releases adrenaline, which is a naturally produced hormone that the body uses during ...
The aim of this study was to evaluate the efficacy and safety of enoximone, an imidazolonic compound inhibiting cardiac phosphodiesterase III, during the postoperative period. The drug was administered prior to the usual stages of weaning the patient off extracorporeal circulation, to a group of 20 subjects who presented an ejection fraction of less than 35% following hemodynamic studies. Patients were randomly subdivided into 4 groups each of which received a different dose of enoximone according to the following protocol: Group A, 1 mg/kg bolus and slow infusion at 10 gamma/kg/min; Group B, 0.5 mg/kg bolus and slow infusion at 15 gamma/kg/min; Group C, 0.5 mg/kg bolus and slow infusion at 10 gamma/kg/min; Group D, slow infusion at 10 gamma/kg/min. The best results in hemodynamic terms and with regard to the positive inotropic and vasodilatory action of the drug in question were obtained in Group C. Increased cardiac output was observed in all patients within 120 minutes of enoximone administration and
Injury results in release of cytoplasmic ATP, which is sensed by monocytes/macrophages via ATP receptor P2X7. This swiftly induces inflammasome activation, caspase-1-dependent cleavage and release of interleukin-1ß (IL-1ß), IL-18 and HMGB1. Excessive systemic IL-1ß release is the first stage of a reaction chain causing SIRS and high patient mortality. IL-1ß is involved in host defense against infections. Pathogen-induced inflammasome activation, however, typically involve ATP-independent pathways. Hence, a-1-antitrypsin, SLPI, CRP, and DPPC inhibit injury induced inflammation but do not inhibit clearance of pathogens. Scope of application: SIRS, Major surgery, Trauma, Extracorporeal circulation (e.g. cardiopulmonary bypass, ECMO), Chronic inflammation, Lung injury SIRS-related multi organ dysfunction (MODS) and acute lung injury (ALI) are among the leading causes of death worldwide. The proposed remedies have the potential to become affordable life-saving medicaments for numerous ...
en] BACKGROUND: Numerous articles describe the reduction of perioperative bleeding by the therapeutic or prophylactic administration of drugs such as prostacyclin, desmopressin, and natural or synthetic antifibrinolytics. METHODS: A review of the literature was carried out to help the reader define the indications of these drugs during cardiopulmonary bypass operations, highlight the questions that remain concerning their indications and modes of action, and suggest future studies to answer these remaining questions. RESULTS: Prostacyclin reduces platelet trauma induced by extracorporeal circulation but does not effectively reduce postoperative bleeding and transfusion requirements. Desmopressin acts as a glue, improving platelet adhesion, and may be effective when postoperative bleeding is excessive, but its routine use in cardiac operations cannot be recommended. Natural and synthetic antifibrinolytics inhibit plasmin and plasmin-induced platelet dysfunction. These agents have been shown to ...
3. to take charge of the administration and guiding of the municipal grain circulation; to study and put forward the scheme of deepening the reform of the grain circulation system and coordinate with relevant authorities to implement; to promote the reform of state-owned grain enterprises; to do a good job in coordination, supervision, inspection and guidance for the reform of state-owned grain procurement and sale enterprises;. 4. to guide, supervise, inspect and serve for the participants in the municipal grain market; to study and put forward the planning of establishing the grain market, coordinate with relevant authorities to manage the grain market and perfect the monitoring and alert system for the grain market; to implement the emergency mechanism for the grain market and put forward suggestions on launching the grain emergency scheme; to take charge of the management of the grain supply to troops and disadvantaged groups as well as the delivery subsidies of the non-staple foodstuff ...
Analysis of traffic impact. The traffic engineer shall evaluate the likely impact of the proposed development in the areas circulation system. Included shall be an evaluation of the proposals likely impact on existing and planned public transportation improvements, the expected impact on pedestrian and nonvehicular circulation, an evaluation of the capacity of existing roadways within the study area to accommodate site-generated traffic, as well as total future traffic demand. (Total future traffic demand shall be defined to include existing vehicular volumes plus traffic volumes associated with approved developments within the study area.) This demand shall consist of a combination of the existing traffic expanded to the completion year (using an annual traffic rate available from Delaware Valley Regional Planning Commission), the development-generated traffic, and the traffic generated by other proposed developments affecting the study area. The traffic engineer shall render an opinion ...
Analysis of traffic impact. The traffic engineer shall evaluate the likely impact of the proposed development in the areas circulation system. Included shall be an evaluation of the proposals likely impact on existing and planned public transportation improvements, the expected impact on pedestrian and nonvehicular circulation, an evaluation of the capacity of existing roadways within the study area to accommodate site-generated traffic, as well as total future traffic demand. (Total future traffic demand shall be defined to include existing vehicular volumes plus traffic volumes associated with approved developments within the study area.) This demand shall consist of a combination of the existing traffic expanded to the completion year (using an annual traffic rate available from Delaware Valley Regional Planning Commission), the development-generated traffic, and the traffic generated by other proposed developments affecting the study area. The traffic engineer shall render an opinion ...
The potential of high efficiency zero-emission engines fueled by hydrogen, which is regarded as a promising form of energy for the future, is being researched. The argon circulated hydrogen engine [ 1 ] is one system theoretically capable of achieving both high efficiency and zero emissions, and its feasibility for use in vehicles has been studied. Specifically, tests were performed to verify the following issues. It was examined whether stable hydrogen combustion could be achieved under an atmosphere of argon and oxygen, which has a high specific heat ratio, and whether the substantial thermal efficiency improvement effect of the argon working gas could be achieved. An argon circulation system was also studied whereby steam, which is the combustion product of the hydrogen and oxygen emitted from the engine, is separated by condensation to enable the remaining argon to be re-used. In addition, the study also examined whether gas impurities accumulated in the circulation gas during continuous ...
... extracorporeal circulation). After the introduction of the initial procedure, a series of improvements were made, culminating ...
... extracorporeal circulation). A series of improvements were made, culminating in 1992 in the Cox maze III procedure, which is ... Circulation. 109 (3): 327-34. doi:10.1161/01.CIR.0000112641.16340.C7. PMID 14707026. Scherlag B, Nakagawa H, Jackman W, ...
Assad RS, Lee FY, Hanley FL (2001). "Placental compliance during fetal extracorporeal circulation". Journal of Applied ... Placental blood circulation Archived 2011-09-28 at the Wayback Machine Kiserud T, Acharya G (2004). "The fetal circulation". ... The fetoplacental circulation is vulnerable to persistent hypoxia or intermittent hypoxia and reoxygenation, which can lead to ... as foreign fetal cells also persist in the maternal circulation, on the other side of the placental barrier. The placenta also ...
Ionescu M.I., Wooler G.H. Current Techniques in Extracorporeal Circulation. Butterworths, (!976), London. Ionescu M.I. Tissue ... Ionescu M.I. Techniques in Extracorporeal Circulation. Butterworths,(1981), London. Ionescu M.I., Cohn L.H. Mitral Valve ... with the aid of extracorporeal circulation, in animals and in man. The body temperature was lowered to between 6 and 15 °C and ... Circulation, 111, 2717-2719 , [5] Bodnar E, Yacoub M, Eds. "Biologic and Bioprosthetic Valves" Proceedings of the Third ...
Melrose, D. G. (1961). "Types Of Heart-Lung Machines Used In Extra-Corporeal Circulation". Postgraduate Medical Journal. 37 ( ... In 1954, Kirklin's rival, C. Walton Lillehei used the technique of cross circulation to operate on an 11-month-old baby who ... Usually using the parent for cross circulation, he performed 45 operations of ventricular septal defects (VSDs), ASDs and ... Cooley Denton A. (22 June 2004). "John W. Kirklin, MD". Circulation. 109 (24): 2928-2929. doi:10.1161/01.CIR.0000133601.16718. ...
It is also can be considered a kind of extracorporeal circulation. There are two primary methods, homologous blood transfusion ... Direct transfusion is a blood salvaging method associated with cardiopulmonary bypass (CPB) circuits or other extracorporeal ... is drained into a re-circulation bag. Before the beginning of the CPB, the crystalloid priming fluid is displaced by the ... blood circulatory and transporting oxygen to red blood cells before blood is flowing backwards the arterial circulation. ...
Gibbon Award for Outstanding Contribution to Science and Practice of Extracorporeal Circulation (2008) • Longmire Legacy Award ...
In patients who are non responsive to this management extra corporeal circulation may be indicated. Each of these strategies ... 1989). "[Surgical treatment of chronic pulmonary embolism using thromboembolectomy under extracorporeal circulation and deep ... In order to achieve this CPB is periodically stopped, resulting in a complete cessation of blood circulation. This is only ... After each interval of arrest circulation is continued for 10 minutes or until pulmonary venous oxygen saturation is at least ...
... s are meant to be used in extracorporeal circulation systems (dialysis for example) or engineered bioreactors; ...
"The first open-heart repairs using extracorporeal circulation by cross-circulation: a 53-year follow-up". Annals of Thoracic ...
Each year, the institute fulfilled about 3000 heart operations, including over 1500 - with extra-corporeal blood circulation. ... including about 36,000 operations with extra-corporeal blood circulation. In 1983 Amosov's cardiac surgery clinic was ... one was one of the first in the Soviet Union to introduce into the practice the method of artificial blood circulation (in 1963 ...
Development of technics employed in extracorporeal circulation in the years 1961-1976 in the light of 1,200 cases]". ...
Assad RS, Lee FY, Hanley FL (2001). "Placental compliance during fetal extracorporeal circulation". Journal of Applied ... Fetoplacental circulationEdit. Further information: Fetal circulation. Deoxygenated fetal blood passes through umbilical ... Placental blood circulation Archived 2011-09-28 at the Wayback Machine *^ a b Kiserud T, Acharya G (2004). "The fetal ... Placental circulationEdit. Maternal blood fills the intervillous space, nutrients, water, and gases are actively and passively ...
Middle East Council of Churches Minimized extracorporeal circulation Missouri Eastern Correctional Center, a male prison in ...
It has been shown to inhibit intrinsic coagulation, inhibit host responses to extracorporeal circulation, and lessen ... "Studies in Extracorporeal Circulation. I. Applicability of Gibbon-Type Pump-Oxygenator to Human Intracardiac Surgery: 40 Cases ... However, oxygenators can also be utilized in extracorporeal membrane oxygenation in neonatal intensive care units by nurses. ... The researchers concluded that Heparin-coated extracorporeal circuits with reduced systemic heparinization lead to ...
Their role is to conduct extracorporeal circulation as well as ensure the management of physiologic functions by monitoring the ... extracorporeal membrane oxygenation (ECMO) Adult surgical procedures may include: coronary artery bypass, aortic valve ... monitoring circulation, monitoring blood gases, surveil anticoagulation, induction of hypothermia, and hemodilution. Sometimes ...
... without the use of machines for extracorporeal circulation) that allows a percentage of revascularization over 90%; the ... Circulation 119, 2702-2707, 2009 A. Panza, R. Leone, A. Longobardi, P. Masiello, A. Alfano, G. Mastrogiovanni, F. Cafarelli, S ... thoracic aorta in a patient of 60 years with an fissured aneurysm without the aid of the machine for extracorporeal circulation ...
Techniques in Extracorporeal Circulation, CRC Press, 2004.. ... Sensors In various medical treatments that use Extracorporeal ...
... when extracorporeal circulation and anticoagulation are no longer needed. It is also used in gene transfer, protein ...
1961;33:1040-3 (pl), PMID 14480650 Experience with heart surgery with the use of extracorporeal circulation, Sitkowski W. Jr, ... 1961 Feb 27;16:321-5 (pl), PMID 13766327 Clinical use of Crafoord-Senning's apparatus for extra-corporeal circulation, Nowicki ... 1973;16(5):391-8 (pl), PMID 4764019 Some hemodynamic problems of extracorporeal circulation perfusion in relation to the ... PMID 5330459 An attempt to analyze hemodynamic changes during the use of extracorporeal circulation, Michałowski J., Manteuffel ...
UD requires the establishment of an extracorporeal circulation through its unique AV loop with two pre-existing arterial and ... It is a useful measurement in fetal circulation, where cardiac outputs from both sides of the heart work partly in parallel by ... These instruments average measurements over 2-9 minutes depending on the stability of the circulation, and thus do not provide ... Ultrasound dilution (UD) uses body-temperature normal saline (NS) as an indicator introduced into an extracorporeal loop to ...
Liver dialysis involves extracorporeal dialysis to remove toxins from the circulation, usually through the addition of a second ... Type 2 HRS is thought to be part of a spectrum of illness associated with increased pressures in the portal vein circulation, ... The predominant theory (termed the underfill theory) is that blood vessels in the kidney circulation are constricted because of ... Deteriorating liver function is believed to cause changes in the circulation that supplies the intestines, altering blood flow ...
... head and neck by chemotherapy via extracorporeal circulation and intracarotid chemotherapy". Revue Médicale du Moyen-Orient. 24 ...
... extracorporeal circulation of blood, in hemolysis requiring alkalinization of the urine to avoid nephrotoxicity of blood ...
This measurement is often used under treatment with a heart lung machine (extracorporeal circulation), and can give the ...
Bone marrow transplantation Liposuction Parenteral lipid infusion Decompression sickness Extracorporeal circulation Acute ... Fat embolism is presence of fat particles in the micro-circulation of the body. Meanwhile, fat embolism syndrome is the ... Biochemical theory - Following trauma, an inflammation causes bone marrow to liberate fatty acids into the venous circulation. ... and heart circulation, causing capillary damage, and subsequently cause organ damage in these areas. There are two theories ...
The idea of an extracorporeal circulation was introduced by him in his 1812 monograph Expériences sur le principe de la vie, ...
... an Italian company that was the European leader in the market for extracorporeal blood circulation and autologous blood ...
Checklist for preoperative extracorporeal circulation equipment setup ISO 23813:2007 Cranes - Training of appointed persons ISO ...
Bubble oxygenator Extracorporeal circulation E. Converse Peirce, made refinements to membrane oxygenator Experiments in the ... In the 1920s and 30s, research into developing extracorporeal oxygenation continued. Working independently, Brukhonenko in the ... termed extracorporeal membrane oxygenation (ECMO). A membrane oxygenator consists of a thin gas-permeable membrane separating ... USSR and John Heysham Gibbon in the US demonstrated the feasibility of extracorporeal oxygenation. Brukhonenko used excised dog ...
... the liver via the portal venous system for further processing and detoxification before returning to the systemic circulation ... Artificial extracorporeal liver support *Bioartificial liver devices. *Liver dialysis. *Hepatectomy. *Liver biopsy ...
Circulation. 75: 505-13. doi:10.1161/01.cir.75.3.505.. .mw-parser-output cite.citation{font-style:inherit}.mw-parser-output q{ ... Extracorporeal membrane oxygenation. *Vascular access. *Revascularization. *First rib resection. *Seldinger technique. * ...
Liver dialysis involves extracorporeal dialysis to remove toxins from the circulation, usually through the addition of a second ... Type 2 HRS is thought to be part of a spectrum of illness associated with increased pressures in the portal vein circulation, ... Deteriorating liver function is believed to cause changes in the circulation that supplies the intestines, altering blood flow ... Both types of hepatorenal syndrome share three major components: altered liver function, abnormalities in circulation, and ...
... and return or exchange of blood plasma or components thereof from and to the blood circulation. It is thus an extracorporeal ... where the rapid removal of disease-causing autoantibodies from the circulation is required in addition to other medical therapy ...
Cases refractory to immunosuppressive or antibody therapy are sometimes treated with photopheresis, or extracorporeal ... "Circulation. 121 (17): 1926-33. doi:10.1161/CIRCULATIONAHA.109.885756. PMC 4273502. PMID 20404257.. ...
Extracorporeal assistance, performance, and therapy (ICD-9-CM V3 99, ICD-10-PCS 5-6) ... ultrasound called sustained acoustic medicine is a daily slow-release therapy that can be applied to increase local circulation ...
Gubisch W (November 2006). "Twenty-five years experience with extracorporeal septoplasty". Facial Plastic Surgery. 22 (4): 230- ... because such health factors negatively affect blood circulation and tissue perfusion, and thus the timely and correct healing ...
Studies of the Circulation with Radioactive Microspheres., Wagner et al, Invest. Radiol., 1969. 4(6): p. 374-386. ... The New Orleans Conference: Practices in Cardiac Surgery and Extracorporeal Technologies. *v ...
systemic circulation to pulmonary artery shunt Blalock-Taussig shunt. SVC to the right PA Glenn procedure. ... Extracorporeal membrane oxygenation. *Vascular access. *Revascularization. *First rib resection. *Seldinger technique. * ...
Gibbon at Jefferson Medical School in Philadelphia reported in 1953 the first successful use of extracorporeal circulation by ... systemic circulation to pulmonary artery shunt Blalock-Taussig shunt. SVC to the right PA Glenn procedure. ... C. Walter Lillihei used cross-circulation between a boy and his father to maintain perfusion while performing a direct repair ... The results of direct vision closure of ventricular septal defects in eight patients by means of controlled cross circulation. ...
Circulation 2001;103:10-13. *^ Kataoka M, Inami T, Hayashida K, Shimura N, Ishiguro H, Abe T,Tamura Y, Ando M, Fukuda K, ... Extracorporeal membrane oxygenationas a bridge to pulmonary endarterectomy. Ann Thorac Surg 2011;92:e101-e103. ... Circulation 2011;124:1973-1981. *^ Berger RM, Beghetti M, Humpl T, Raskob GE, Ivy DD, Jing ZC, Bonnet D, Schulze-Neick I, Barst ... Venovenous extracorporeal life support after pulmonaryendarterectomy: indications, techniques, and outcomes.Ann Thorac Surg ...
"Circulation. doi:10.1161/CIRCULATIONAHA.114.014542.. *^ a b Davis, Robert (July 28, 2003). "Special report: Many lives are lost ... "Recovery of a hypothermic drowned child after resuscitation with cardiopulmonary bypass followed by prolonged extracorporeal ... "Circulation. 133 (4): e38-e360. doi:10.1161/CIR.0000000000000350.. *^ Go, Alan S.; Mozaffarian, Dariush; Roger, Véronique L.; ... "Circulation. 139 (10): e56-e528. doi:10.1161/CIR.0000000000000659.. *^ Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, ...
systemic circulation to pulmonary artery shunt Blalock-Taussig shunt. SVC to the right PA Glenn procedure. ... Artificial extracorporeal liver support *Bioartificial liver devices. *Liver dialysis. *Hepatectomy. *Liver biopsy ...
systemic circulation to pulmonary artery shunt Blalock-Taussig shunt. SVC to the right PA Glenn procedure. ...
Circulation. 112 (3): 416-22. doi:10.1161/circulationaha.104.512834. PMID 16009794.. ...
Other medical concepts - Acute medicine, American Academy of Dermatology, Circulation (journal), Clinical Medicine, Coffee and ... Extracorporeal carbon dioxide removal (T), Hickman line, Kidney transplantation, LDL apheresis, Liver biopsy (was redirect, got ...
systemic circulation to pulmonary artery shunt Blalock-Taussig shunt. SVC to the right PA Glenn procedure. ... This is done to avoid the reduced diastolic blood flow in the coronary circulation associated with the Blalock-Taussig shunt. ... Extracorporeal membrane oxygenation. *Vascular access. *Revascularization. *First rib resection. *Seldinger technique. * ...
A coronary angiogram (an X-ray with radio-opaque contrast in the coronary arteries) that shows the left coronary circulation. ... After successful dilation of the stenosis with a guide wire and coaxial Teflon catheters, the circulation returned to her leg. ... Extracorporeal membrane oxygenation. *Vascular access. *Revascularization. *First rib resection. *Seldinger technique. * ...
"Circulation. 132 (18 Suppl 2): S526-42. doi:10.1161/cir.0000000000000266. PMC 6191296. PMID 26473000.. ... Extracorporeal membrane oxygenation may be used in those who are about to go into cardiac arrest.[28] ... "Myocarditis" Archived 2013-12-16 at the Wayback Machine, Circulation, 113:876-890. ...
... veins and lymphatic circulation, are managed by medical therapy, minimally-invasive catheter procedures, and surgical ... Extracorporeal membrane oxygenation. *Vascular access. *Revascularization. *First rib resection. *Seldinger technique. * ...
Aug 2012). "A feasibility study evaluating the role of cerebral oximetry in predicting return of spontaneous circulation in ... extracorporeal membrane oxygenation, brain oximetry, and prevention of reperfusion injury, and wrote his book, Reversing Death ... May 2015). "Cerebral oximetry levels during CPR are associated with return of spontaneous circulation following cardiac arrest ...
A centrifugal artificial heart which alternately pumps the pulmonary circulation and the systemic circulation, causing a pulse ... In 2012, a study published in the New England Journal of Medicine compared the Berlin Heart to extracorporeal membrane ... Prolonged Assisted circulation after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of ... Cohrs Nicholas H (2017). "A Soft Total Artificial Heart-First Concept Evaluation on a Hybrid Mock Circulation". Artificial ...
The risk is increased with use of extracorporeal membrane oxygenation in preterm infants.[12] Congenital cytomegalovirus ... Persistent fetal circulation. Haemorrhagic and. hematologic disease. *Vitamin K deficiency bleeding. *HDN *ABO ...
The Extracorporeal Liver Assist Device (ELAD) is a human-cell based treatment system. A catheter removes blood from the patient ... However, after 3 hours of plasma circulation, hepatocyte function deteriorated rapidly. This was likely due to the toxic effect ... Manz, T; Ochs, A; Bisse, E; Strey, C; Grotz, W (2003). "Liver support--a task for nephrologists? Extracorporeal treatment of a ... Parés, A; Cisneros, L; Salmerón, JM; Caballería, L; Mas, A; Torras, A; Rodés, J (Jun 2004). "Extracorporeal albumin dialysis: a ...
... as opposed to extracorporeal procedures (e.g. extracorporeal membrane oxygenation). In a medical or surgical context, it may ... refer to: Intracorporeal anastomosis Intracorporeal circulation Intracorporeal energy harvesting, harvesting energy from the ... Intracorporeal or intracorporal is an adjective that means within (intra-) the body (corpus). Its antonym is extracorporeal. It ...
August 2015). "Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal ... Towler MC, Hardie DG (February 2007). "AMP-activated protein kinase in metabolic control and insulin signaling". Circulation ... Extracorporeal treatments are recommended in severe overdoses. Due to metformin's low molecular weight and lack of plasma ...
Some protoporphyrin in bile is returned to the liver as a consequence of the enterohepatic circulation; the remaining ... Bone marrow transplantation, liver transplantation, acetylcysteine, extracorporeal albumin dialysis, parenteral iron and ... interrupting the enterohepatic circulation. It is usually used in combination with other treatment approaches. Activated ...
The main advantage of this system is the low extracorporeal volume (calculated by volume of the apheresis chamber, the donor's ... is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation. It ... is thus an extracorporeal therapy. The apheresis machine was invented by American medical technologist Herb Cullis in 1972. One ...
EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 6 INVENTORS la/w 1% 67.950 J2, Gus/7w K17. MAI/V845 Jo/r/v ... Oxygenating unit for extracorporeal circulation devices. US2876769 *. Oct 11, 1955. Mar 10, 1959. Cordova Jose Juan. Apparatus ... EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 9 e54 PM W ATTORNEY Nov. 17, 1953 J. H. GIBBON, JR., ET AL ... Extracorporeal blood circulation system having a non-electric drive. US3064649 *. Oct 1, 1959. Nov 20, 1962. Hemathermatrol ...
Minimized extracorporeal circulation (MECC) is a kind of cardiopulmonary bypass (heart-lung machine), a part of heart surgery. ... The introduction of extracorporeal circulation has facilitated open heart surgery. The development of modern techniques in ... The benefits of this type of extracorporeal circulation are that a lower consumption of blood and blood products is observed in ... In 1937 Gibbon reports the first successful use of extracorporeal circulation in animals (in this case, cats). On May 6, 1953 ...
... Shuhua Luo,1 Menglin Tang,2 Lei Du,3 Lina Gong,3 Jin Xu,4 ... Shuhua Luo, Menglin Tang, Lei Du, et al., "A Novel Minimal Invasive Mouse Model of Extracorporeal Circulation," Mediators of ...
p,The extracorporeal circulation apparatus used in the sel ... The extracorporeal circulation apparatus used in the selective ... An extracorporeal circulation apparatus capable of maintaining hypothermia for a prolonged period when used in the selective ... wherein the extracorporeal circulation method according to the second aspect is performed using the extracorporeal circulation ... The extracorporeal circulation apparatus shown in FIG. 1. comprises a diluent supply unit comprising a diluent container (. 8. ...
... Jonsson, Ove Uppsala University, Disciplinary ... and extracorporeal circulation following progressive venous stasis.. Hypothermic circulatory arrest induced a metabolic pattern ... especially in cases of compromised arterial flow during extracorporeal circulation.. In conclusion, cerebral metabolism and ...
... for the group using extracorporeal circulation versus 3.2% for the group not using extracorporeal circulation. In regard to ... without extracorporeal circulation with 30 patients undergoing myocardial revascularization with extracorporeal circulation. In ... circulation, although surgery with extracorporeal circulation was a safe and well-established procedure 26-31. The major ... revascularization without extracorporeal circulation is to reduce surgical risk and the consequences of using extracorporeal ...
New Therapeutic Method Against Septic Shock - Removal of Endotoxin Using Extracorporeal Circulation. ... Removal of Endotoxin Using Extracorporeal Circulation. In: Friedman H., Klein T.W., Nakano M., Nowotny A. (eds) Endotoxin. ...
Extracorporeal Circulation Without Bleeding Message Subject. (Your Name) has forwarded a page to you from Science Translational ... A newly created antibody to the active site of Factor XIIa protects against clotting of extracorporeal bypass circuitry without ... A newly created antibody protects against blood coagulation in extracorporeal bypass systems without bleeding risk in vivo. ... A newly created antibody protects against blood coagulation in extracorporeal bypass systems without bleeding risk in vivo. ...
... Y. Denizot,1 ... Leukocytosis and thrombocytopenia occur during cardiopulmonary bypass (CPB) with extracorporeal circulation (ECC). Elevated ...
Removal of Cytokines During Extracorporeal Circulation in Cardiac Surgery. The safety and scientific validity of this study is ... At the end of extracorporeal circulation a rotation thromboelastometry analysis is performed and the clotting time (CT), the ... Reduction of Inflammation Reaction to Extracorporeal Circulation in Cardiac Surgery by Interleukin Dialysis. ... filter in the cardiopulmonary circuit attenuates the inflammatory response to extracorporeal circulation in patients undergoing ...
What is extracorporeal circulation? Meaning of extracorporeal circulation as a finance term. What does extracorporeal ... Definition of extracorporeal circulation in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... Related to extracorporeal circulation: Extracorporeal membrane oxygenation. circulation. Areas in an office space that are used ... circulation. (redirected from extracorporeal circulation). Also found in: Dictionary, Thesaurus, Medical, Acronyms, ...
Background-Extracorporeal membrane oxygenation (ECMO) has served for ,2 decades as the standard of care for US children ... Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person ... Extracorporeal Membrane Oxygenation for Bridge to Heart Transplantation Among Children in the United States. Analysis of Data ... Extracorporeal Membrane Oxygenation for Bridge to Heart Transplantation Among Children in the United States ...
Controversy on superiority of pulsatile versus non-pulsatile extracorporeal circulation in cardiac surgery still continues. ... Controversy on superiority of pulsatile versus non-pulsatile extracorporeal circulation in cardiac surgery still continues. ... elucidate the impact of our findings on the scientific discourse of pulsatile versus non-pulsatile extracorporeal circulation. ... under the influence of antegrade or retrograde perfusion with pulsatile versus non-pulsatile extracorporeal circulation. While ...
... ... Clinical cases of normothermic extracorporeal circulation (ECC) are increasing, but the possibility of brain damage is not ...
Principles of Miniaturized ExtraCorporeal Circulation - Author: Anastasiadis, Kyriakos - Price: 190,65€ ... Principles of Miniaturized ExtraCorporeal Circulation. 190,65€. Add to cart. Ebook, PDF with Adobe DRM. ISBN: 9783642327568. ...
Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation. The ... The aim of this study is to assess the effect of minimal (MECC) versus conventional (CECC) extracorporeal circulation on ... Procedure: Coronary artery bypass grafting with the use of minimal extracorporeal circulation Procedure: Coronary artery bypass ... Procedure: Coronary artery bypass grafting with the use of minimal extracorporeal circulation The MECC system (Maquet ...
OBJECTIVE: The role of leptin in the acute stress response to extracorporeal circulation has been well documented, however, the ... We aimed to research the circulating leptin, zinc, and copper levels before, during, and after the extracorporeal circulation, ... CONCLUSIONS: These results indicate that circulating leptin levels increase after the extracorporeal circulation as an acute ... METHODS: Twenty patients who were taken to elective coronary artery bypass grafting operations using extracorporeal circulation ...
Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person ... Introduction: Extracorporeal Membrane Oxygenation (ECMO) serves as a mechanical circulatory support bridge to recovery in ... Abstract 13523: Extracorporeal Membrane Oxygenation Stimulates Myocardial Protein Synthesis without Altering Leucine Oxidation ... Abstract 13523: Extracorporeal Membrane Oxygenation Stimulates Myocardial Protein Synthesis without Altering Leucine Oxidation ...
A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk ... A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk ... A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk ... A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk ...
Home » Leucocyte depletion in a drowning victim during rewarming with extracorporeal circulation may limit pulmonary oedema ... Leucocyte depletion in a drowning victim during rewarming with extracorporeal circulation may limit pulmonary oedema. ... Methods: In the first patient, a standard extracorporeal circuit was used. In the second patient, systemic leucocyte depletion ... two drowning victims with hypothermic circulatory arrest who were resuscitated with the use of extracorporeal circulation (ECC ...
... ... The proposed CS method for the analysis of blood flow from the aortic cannulae during extracorporeal circulation can reproduce ...
A biomaterial with both antithrombin and antiplatelet properties is the ideal surface for use in extracorporeal circulation ( ... A biomaterial with both antithrombin and antiplatelet properties is the ideal surface for use in extracorporeal circulation ( ... of a direct thrombin inhibitor to a polyurethane as a nonthrombogenic surface coating for extracorporeal circulation J. Yu, E. ... of a direct thrombin inhibitor to a polyurethane as a nonthrombogenic surface coating for extracorporeal circulation ...
Myocardial revascularization with miniaturized extracorporeal circulation versus off pump: Evaluation of systemic and ... AdultAgedAged, 80 and overCoronary AngiographyCoronary Artery Bypass, Off-PumpCoronary DiseaseExtracorporeal CirculationFemale ... Miniaturized extracorporeal circulation can be considered similar to off-pump surgery in terms of systemic inflammatory ... Levels of creatine kinase mass were statistically higher in the miniaturized extracorporeal circulation group than in the off- ...
... S Jacobs, Filip De Somer (UGent) , GUY ... "Active or Passive Bio-coating : Does It Matters in Extracorporeal Circulation?" PERFUSION-UK 26.6 (2011): 496-502. Print. ... "Active or Passive Bio-coating : Does It Matters in Extracorporeal Circulation?" Perfusion-uk 26 (6): 496-502. ... does it matters in extracorporeal circulation? PERFUSION-UK, 26(6), 496-502. ...
Clinical evaluation of Duraflo? II heparin treated extracorporeal circulation circuits (2nd version) the European working group ... on heparin coated extracorporeal circulation circuits Journal. European journal of cardio-thoracic surgery. Volume. 11. Pages ( ...
Extracorporeal Circulation*. Hemodynamics. Humans. Middle Aged. Mitral Valve / surgery. Mitral Valve Insufficiency / ... in patients with MVD before and after induction of anesthesia and during and after surgery when extracorporeal circulation (ECC ...
Simple and choice reaction times are prolonged following extracorporeal circulation: a potential method for the assessment of ... Extracorporeal Circulation - adverse effects, Cognition Disorders - physiopathology, Adult, Regression Analysis, Thoracic ...
... prevents complex formation between tissue factor and factor VII/VIIa and thus inhibits coagulation of blood in extracorporeal ... This invention provides a method of inhibiting coagulation in extracorporeal circulation in a subject, comprising ... Simulated Extracorporeal Circulation. a. Antibodies. Murine monoclonal antibodies TF8-5G9, TF9-6B4 and TF9-9C3 to human TF ( ... Method of inhibiting blood coagulation in extracorporeal circulation by inhibiting human tissue factor Download PDF Info. ...
Lung Transplantation in Cystic Fibrosis and the Impact of Extracorporeal Circulation El trasplante pulmonar en la fibrosis ... The impact of extracorporeal circulation (ECC) during transplantation has not been fully clarified. This study aimed to ... June 2018 Lung Transplantation in Cystic Fibrosis and the Impact of Extracorporeal Circulation ...
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  • Also in patients treated with extracorporeal membrane oxygenation (ECMO) an activation of the inflammation system is seen and accompanied with an increase of cytokine levels. (clinicaltrials.gov)
  • Extracorporeal Membrane Oxygenation (ECMO) serves as a mechanical circulatory support bridge to recovery in children, allowing the heart to overcome severe insults such as ischemia/reperfusion injury. (ahajournals.org)
  • Indication for initiation of mechanical circulatory support impacts survival of infants with shunted single-ventricle circulation supported with extracorporeal membrane oxygenation. (harvard.edu)
  • Extracorporeal membrane oxygenation (ECMO) is a means of supporting severe pulmonary and cardiac dysfunction. (springer.com)
  • Treatment with prolonged extracorporeal oxygenation. (springer.com)
  • Extracorporeal membrane oxygenation (ECMO) cardiopulmonary support in infancy. (springer.com)
  • Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. (springer.com)
  • Early and late outcomes of 517 consecutive adult patients treated with extracorporeal membrane oxygenation for refractory postcardiotomy cardiogenic shock. (springer.com)
  • UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. (springer.com)
  • Extracorporeal membrane oxygenation in severe acute respiratory failure. (springer.com)
  • Extracorporeal membrane oxygenation: a ten-year experience. (springer.com)
  • High survival rate in 122 ARDS patients managed according to a clinical algorithm including extracorporeal membrane oxygenation. (springer.com)
  • More than the past years, an increasing number of centers changed their standard for intraoperative ECC from cardiopulmonary bypass (CPB) to extracorporeal membrane oxygenation (ECMO) - with differing results. (ovid.com)
  • Extracorporeal membrane oxygenation treatment tended to be superior regarding 3 month mortality (odds ratio = 0.46, 95% CI = 0.21-1.02) and 1 year mortality (odds ratio = 0.65, 95% CI = 0.37-1.13). (ovid.com)
  • Oxygenation of the patients with tracheal stenosis under anesthesia can be provided by many traditional techniques such as intubation or tracheotomy, while extracorporeal circulation is an unusal method. (dergisi.org)
  • Due to the location and structure of the lesion, safety of airway of the patient would not be provided by routine methods, hence, a stent was decided to be placed on stenotic segment of the trachea under oxygenation with extracorporeal circulation. (dergisi.org)
  • After heparinization, oxygenation was achieved by extracorporeal circulation. (dergisi.org)
  • During the anesthesia of airway surgery, oxygenation with extracorporeal circulation application is a life-saving strategy. (dergisi.org)
  • Extracorporeal membrane oxygenation (ECMO) is a well-established therapy for the temporary substitution for the heart and/or lungs in patients with acute cardiac or pulmonary failure. (intechopen.com)
  • The use of extracorporeal membrane oxygenation (ECMO), as a therapy for acute cardio-pulmonary failure, as a form of "substitute" for the full circulation has undergone extensive development over the years. (intechopen.com)
  • Therefore, as with new methods for external blood circulation (extracorporeal support), membrane oxygenation was used in cases of dying patients and the outcomes, predictably, were poor [ 3 ]. (intechopen.com)
  • This patient was also the first with influenza A (H1N1) to be supported with extracorporeal membrane oxygenation in Hong Kong. (hkmj.org)
  • Although extracorporeal membrane oxygenation is an effective means of supporting patients with refractory hypoxaemia on high mechanical ventilatory support, it is labour-intensive and technically demanding. (hkmj.org)
  • Pharmacokinetic alterations of medications administered during surgeries involving cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) have been reported. (mdpi.com)
  • While CPB usually lasts a few hours, extracorporeal membrane oxygenation (ECMO), a modified application of CPB concept, provides longer-term extracorporeal life support (days to weeks) as a bridge to recovery or a bridge to transplant or a destination device [ 1 ]. (mdpi.com)
  • The invention concerns a device for gas exchange, in particular oxygenation of blood, with a gas exchanger which is divided by a semipermeable membrane into a blood chamber and a gas exchange chamber, whereby an extracorporeal blood path is run through the blood chamber and a gas path is run through the gas exchange chamber. (google.es)
  • Examining the role of extracorporeal membrane oxygenation in patients following suspected or. (deepdyve.com)
  • Ventetuolo, Corey E. 2018-04-01 00:00:00 The decision to offer extracorporeal membrane oxygenation (ECMO) is based on a risk/benefit assessment and the likelihood of a treatable underlying condition or the feasibility of destination therapy (durable mechanical support or thoracic organ transplantation) should heart-lung function fail to improve. (deepdyve.com)
  • In these infants, the evidence would suggest that extracorporeal membrane oxygenation (ECMO) is the most effective mode of treatment. (bmj.com)
  • Venoarterial extracorporeal membrane oxygenation (ECMO) is used primarily in the treatment of lung disease. (encyclopedia.com)
  • Minimized extracorporeal circulation (MECC) is a kind of cardiopulmonary bypass (heart-lung machine), a part of heart surgery. (wikipedia.org)
  • The benefits of this type of extracorporeal circulation are that a lower consumption of blood and blood products is observed in the peri-operative and post-operative phase and that a lower inflammatory response is being measured in peri-operative blood samples in comparison to conventional cardiopulmonary bypass. (wikipedia.org)
  • Leukocytosis and thrombocytopenia occur during cardiopulmonary bypass (CPB) with extracorporeal circulation (ECC). (hindawi.com)
  • The aim of this study is to prove that using a CytoSorb (TM) filter in the cardiopulmonary circuit attenuates the inflammatory response to extracorporeal circulation in patients undergoing cardiac surgery. (clinicaltrials.gov)
  • Among their topics are the historical development of minimized cardiopulmonary bypass, the blood-surface interface in miniaturized extracorporeal circulation systems, myocardial preservation techniques for mini-bypass, valve surgery using minimized perfusion circuits, and comparing minimized circulation with off-pump coronary artery bypass grafting and conventional surgery. (thefreedictionary.com)
  • The method prevents complex formation between tissue factor and factor VII/VIIa and thus inhibits coagulation of blood in extracorporeal procedures such as cardiopulmonary bypass and other shunt procedures. (google.com)
  • To evaluate the clinical results of aortic valve replacement performed with a miniaturized closed circuit extracorporeal circulation (MECC) system and to compare it to standard cardiopulmonary bypass (CPB). (semanticscholar.org)
  • Oxygen delivery during cardiopulmonary bypass (and renal outcome) using two systems of extracorporeal circulation: a retrospective review. (semanticscholar.org)
  • Comparison of minimally invasive closed circuit extracorporeal circulation with conventional cardiopulmonary bypass and with off-pump technique in CABG patients: selected parameters of coagulation and inflammatory system. (semanticscholar.org)
  • Aortic valve replacement with the minimal extracorporeal circulation (Jostra MECC System) versus standard cardiopulmonary bypass: a randomized prospective trial. (semanticscholar.org)
  • Minimal extracorporeal circulation (MECC) systems have been designed in order to reduce dramatically the side-effects of conventional extracorporeal circulation while serving as a safe perfusion technique for open heart surgery with cardiopulmonary bypass. (medical-ebooks.net)
  • This study was designed to compare, at profound hypothermia, continuous cardiopulmonary bypass, SCP and circulatory arrest in a survival model of extracorporeal circulation in immature swine. (elsevier.com)
  • The objective of this study was to evaluate the ABPTs in minimalized extracorporeal cardiopulmonary (MECC TM ) compared with standard open system on-pump coronary revascularization. (opencardiovascularmedicinejournal.com)
  • Methods and Results- Data from the Extracorporeal Life Support Organization Registry and the Organ Procurement Transplant Network database were merged to identify children supported with ECMO and listed for heart transplantation from 1994 to 2009. (ahajournals.org)
  • Extracorporeal carbon dioxide removal (ECCO 2 R) is similar in concept to ECMO, but has a lower flow rate and does not significantly oxygenate the patient. (springer.com)
  • Extracorporeal circulation (ECMO) in neonatal respiratory failure. (springer.com)
  • Historic milestones of ECMO development track closely the rapid development of other similar medical technologies over the past 50 years-specifically, the development of a number of clinically useful portable extracorporeal biocompatible blood pumps and membrane oxygenators. (intechopen.com)
  • The extracorporeal circuit has three main components: large-bore cannulae and circuit tubing to provide access to the native circulation, an artificial membrane lung to provide gas exchange, and an active pump to facilitate perfusion. (springer.com)
  • A gas exchange device (100) with an extracorporeal blood circuit (102) in which a blood pump (110) is connected, with a CO2 exchange unit (112), and an oxygenator (128), whereby the gas exchange unit (112, 128) is in each case divided by a hydrophilic, water-wet membrane (114, 130) into a blood chamber. (google.es)
  • The aim of this study is to assess the effect of minimal (MECC) versus conventional (CECC) extracorporeal circulation on neurocognitive function after elective coronary bypass grafting (CABG) as well as whether this can be attributed to improved cerebral perfusion intraoperatively. (clinicaltrials.gov)
  • In an attempt to reduce CPB-inherent side effects, a minimal extracorporeal circulation (MECC) system was developed and it is evaluated in clinical practice. (clinicaltrials.gov)
  • We tried to make it less invasive for our patients with the introduction of the MECC (Minimized Extra Corporeal Circulation, Getinge) system on a HL30 heart lung machine (Getinge). (heartbeat5.nl)
  • A custom-made circuit was created to allow the use of Mini Extra Corporeal Circulation (MECC) but permitting the switch to a closed siphon drainage system in the case of difficulties. (biomedcentral.com)
  • Cardio Pulmonary Bypass (CPB) was performed using a closed custom-made circuit designed to perform Mini-extracorporeal circulation (MECC). (biomedcentral.com)
  • Novel techniques are sought to tackle the shortcomings of CPB, among them off-pump coronary artery bypass (OPCAB) and miniaturized extracorporeal circulation (MECC) systems have been extensively tested in randomized controlled trials (RCTs). (ox.ac.uk)
  • To assess perioperative safety and efficacy of MECC and OPCAB when compared with conventional extracorporeal circulation (CECC). (ox.ac.uk)
  • CONCLUSIONS: MECC and OPCAB both improve perioperative outcomes following coronary bypass surgery when compared with conventional CABG performed with extracorporeal circulation. (ox.ac.uk)
  • BackgroundImpact of minimized extracorporeal circulation MECC for coronary surgery on mortality remains controversial and gender significantly influence outcome. (duhnnae.com)
  • Using propensity score matching after binary logistic regression, 1,005 patients from 1,119 patients undergoing surgery with MECC could be matched with 1,005 patients from 2,020 patients undergoing surgery with conventional extracorporeal circulation CECC. (duhnnae.com)
  • 83 patients were operated by the MECC technique and 73 were treated by standard extracorporeal circulation (sECC). (opencardiovascularmedicinejournal.com)
  • We report the case of 70-year-old man with congestive dilated cardiomyopathy and bioprosthetic mitral valve who underwent surgical implantation of the Jarvik 2000® LVAD, using the miniaturized extracorporeal circulation (MECC) system. (elsevier.com)
  • The MECC system obliterated the adverse effects associated with conventional extracorporeal circulation, which are often fatal in critically-ill patients. (elsevier.com)
  • The hypothesis is that removing cytokines from patients' blood by the CytoSorb device significantly improves circulation and outcome in patients undergoing on-pump cardiac surgery. (clinicaltrials.gov)
  • Pulsatile extracorporeal circulation during on-pump cardiac surgery enhances aortic wall shear stress. (biomedsearch.com)
  • Controversy on superiority of pulsatile versus non-pulsatile extracorporeal circulation in cardiac surgery still continues. (biomedsearch.com)
  • Implications for anesthesia, extracorporeal circulation, and cardiac surgery. (biomedsearch.com)
  • BACKGROUND: The aim of this study was to evaluate the safety and efficacy of the percutaneous cannulation of the internal jugular venous (PCIJV) for extracorporeal circulation during minimally invasive cardiac surgery (MICS) in children with simple congenital heart disease. (minervamedica.it)
  • To determine the frequency of thrombocytopenia associated multi organ failure without infection criteria and its impact on the evolution and survival of patients undergoing cardiac surgery with extracorporeal circulation and prognosis. (oatext.com)
  • Longitudinal, prospective, observational study to determine the frequency in the presentation of thrombocytopenia associated with multiple organ failure in patients undergoing cardiac surgery under extracorporeal circulation without positive infection rates, admitted to the intensive care unit surgical (ICU). (oatext.com)
  • The incidence of TAMOF associated with extracorporeal circulation during cardiac surgery in children and its role in impoverishment within the prognosis makes it important to identify this entity to establish action measures with appropriate therapies for these patients. (oatext.com)
  • A major benefit of CPB is that it provides a bloodless heart for cardiac surgery, with blood flow diverted to an extracorporeal circuit. (mdpi.com)
  • This thesis aimed to investigate cerebral metabolism and perfusion abnormalities in pigs during hypothermic circulatory arrest, selective antegrade cerebral perfusion (SACP) and extracorporeal circulation following progressive venous stasis. (diva-portal.org)
  • As venous pressure increased, the mean arterial pressure stayed more or less unchanged, generating reduced cerebral perfusion pressure and consequently an increased risk of ischaemia, which may impair cerebral perfusion, especially in cases of compromised arterial flow during extracorporeal circulation. (diva-portal.org)
  • Mucosal perfusion impairment and reperfusion injury following the stabilization of systemic circulation due to extracorporeal circulation therapy might cause the injury of the mucosal vessel endothelium. (thefreedictionary.com)
  • The present study employs computational fluid dynamics to evaluate the aortic blood flow and wall shear stress profiles under the influence of antegrade or retrograde perfusion with pulsatile versus non-pulsatile extracorporeal circulation. (biomedsearch.com)
  • The authors hypothesized that ventilation-perfusion (VA/Q) inequality is more pronounced in patients with MVD before and after induction of anesthesia and during and after surgery when extracorporeal circulation (ECC) is used. (biomedsearch.com)
  • EBCP CEU's The European Board of Cardiovascular Perfusion, EBCP, awarded this 17th European Congress on Extracorporeal Circulation Technology, with 8 recertification points. (fecect.org)
  • Minimal invasive extracorporeal circulation (MiECC) has initiated important new efforts within science and technology towards a more physiologic perfusion. (amsect.org)
  • The Brazilian Society for Cardiovascular Surgery (SBCCV) represented by its Department for Mechanical Circulatory Assistance (DECAM) and the the Brazilian Society for Extracorporeal Circulation (SBCEC) conducted a careful critical review of current clinical perfusion practices in Brazil. (bjcvs.org)
  • An extracorporeal circulation apparatus capable of maintaining hypothermia for a prolonged period when used in the selective cooling method. (freepatentsonline.com)
  • These data raise the possibility that profound hypothermia alone during extracorporeal support may produce this observed brain injury. (elsevier.com)
  • In severe cases of hypothermia, patient body temperature can be corrected by extracorporeal circulation with the heart-lung machine. (encyclopedia.com)
  • In the second patient, systemic leucocyte depletion was applied using leucocyte-depletion filters (Pall RS 1, Pall, Portsmouth, UK), in the venous side of the extracorporeal circuit. (ebscohost.com)
  • This prospective randomized study sought to verify the systemic inflammatory response, inflammatory myocardial damage, and early clinical outcome in coronary surgery with the miniaturized extracorporeal circulation system or on the beating heart. (unboundmedicine.com)
  • Miniaturized extracorporeal circulation can be considered similar to off-pump surgery in terms of systemic inflammatory response, myocardial inflammation and damage, and early outcome. (unboundmedicine.com)
  • Low dose systemic heparinization combined with heparin-coated extracorporeal circulation. (minervamedica.it)
  • Uncontrolled systemic-to-pulmonary shunt results in decreased systemic flow during extracorporeal life support (ECLS). (nebraska.edu)
  • The blood-surface interaction during extracorporeal life support therapies requires the use of systemic anticoagulation to decrease the risk of clotting. (frontiersin.org)
  • The focus of this paper will be to review both present and future novel surface modifications that can obviate the need for systemic anticoagulation during extracorporeal life support therapies. (frontiersin.org)
  • During the first half of the 20th century scientists refined their methods in the development of extracorporeal circulation so that it could be used in humans. (wikipedia.org)
  • Methods: In the first patient, a standard extracorporeal circuit was used. (ebscohost.com)
  • Although those with an 3D-MID pdf techniques in extracorporeal circulation are the JavaScript to Sign, get and argue studies, there is a club of local icon on Case outlets and methods for this true disability. (pointsix.com)
  • An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. (freepatentsonline.com)
  • Extracorporeal circulation (ECC) methods are being increasingly used for mechanical support of respiratory and cardio-circulatory failure. (mdpi.com)
  • RL: Mao was that the years of the pdf techniques in extracorporeal at interface of the download existing abstract are in the loud couple, the other example, of private License. (pointsix.com)
  • Why Use Biocompatible Surfaces for Extracorporeal Circulation Circuits? (medtronic.com)
  • Reduced platelet activation and thrombosis in extracorporeal circuits coated with nitric oxide release polymers. (naver.com)
  • The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer. (naver.com)
  • The development of modern techniques in extracorporeal circulation is the result of the combined efforts of physiologists, physicians, and engineers. (wikipedia.org)
  • Young Uzbeki pdf techniques in extracorporeal circulation at after development, ways. (pointsix.com)
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  • Recent studies have shown a significant relationship between intraoperative cerebral oxygen desaturation, indicative of cerebral ischemia, and early POCD in patients undergoing elective coronary bypass grafting (CABG) with conventional extracorporeal circulation (CECC). (clinicaltrials.gov)
  • The model was tested by using clinical monitoring data during extracorporeal circulation of patients undergoing aorto-coronary bypass grafting as input data, and comparing the model output with the results of conventional blood gas analyses (Rapidlab 288 ® ) retrospectively. (springer.com)
  • Safety and efficacy of miniaturized extracorporeal circulation when compared with off-pump and conventional coronary artery bypass grafting: evidence synthesis from a comprehensive Bayesian-framework network meta-analysis of 134 randomized controlled trials involving 22 778 patients. (ox.ac.uk)
  • Then, the dogs were resuscitated by veno-arterial extracorporeal circulation (ECO) and DC counter with IV injection of 1 mg of adrenaline. (nii.ac.jp)
  • A centrifugal or roller head pump can be used in the arterial position for extracorporeal circulation of the blood. (encyclopedia.com)
  • Comparison of minimally invasive closed circuit versus standard extracorporeal circulation for aortic valve replacement: a randomized study. (semanticscholar.org)
  • This report provides in depth study of "Extracorporeal Shock Wave Lithotripsy Market" using SWOT analysis i.e. (openpr.com)
  • According to Market Analyst, Global Extracorporeal Shock Wave Lithotripsy Market is projected to grow at a healthy growth rate from 2018 to 2022. (openpr.com)
  • Global Extracorporeal Shock Wave Lithotripsy Market Report covers the manufacturersdata, including: shipment, price, revenue, gross profit, interview record, business distribution etc., these data help the consumer know about the competitors better. (openpr.com)
  • Extracorporeal Shock Wave Lithotripsy (ESWL) is used for treatment of kidney and ureter stones. (openpr.com)
  • The developing health care infrastructure by and availability of technically developed equipment to carry out the procedure are the vital drivers for the extracorporeal shock wave lithotripsy market. (openpr.com)
  • In addition, the rising prevalence and incidences of kidney stones and ureter stones are expected to fuel the extracorporeal shock wave lithotripsy market. (openpr.com)
  • Regionally, North America held the largest share in the extracorporeal shock wave lithotripsy throughout the forecast period. (openpr.com)
  • Europe is the second largest extracorporeal shock wave lithotripsy market due to increased government investment fueling the market growth. (openpr.com)
  • Further simulations and experimental work are necessary to elucidate the impact of our findings on the scientific discourse of pulsatile versus non-pulsatile extracorporeal circulation. (biomedsearch.com)
  • The purpose of this study was to directly compare the effects of pulsatile versus non-pulsatile circulation to coronary artery flow and myocardial preservation in a cardiac arrest condition. (elsevier.com)
  • On the contrary a more aggressive approach with open aortic surgical repair under extracorporeal circulation and hypothermic arrest has been proposed as a definite treatment of aortic arch thrombus. (thefreedictionary.com)
  • The proposed CS method for the analysis of blood flow from the aortic cannulae during extracorporeal circulation can reproduce the flow velocity and flow pattern in the proximal and transverse aortic arches. (ovid.com)
  • Minimal access aortic valve replacement using minimal extracorporeal circuit. (semanticscholar.org)
  • Treatment of severe acute respiratory distress syndrome: role of extracorporeal gas exchange. (springer.com)
  • Patients operated for elective coronary artery bypass grafting with the use of minimal extracorporeal circulation. (clinicaltrials.gov)
  • AmSECT : Blogs : Quantification of Operational Learning in Minimal Invasive Extracorporeal Circulation. (amsect.org)
  • Quantification of Operational Learning in Minimal Invasive Extracorporeal Circulation. (amsect.org)
  • Ankeney 10 and, in the 1980s, Benetti 11 and Buffolo et al 12 systematized the procedure of myocardial revascularization without extracorporeal circulation and began to use it in patients at higher risk, avoiding extracorporeal circulation and aorta handling to reduce postoperative complications. (scielo.br)
  • 2. The extracorporeal circulation apparatus according to claim 1, wherein said blood concentration unit includes a drawing-out/fluid supply pump to meter the diluted blood from a blood vessel of the mammal, and a blood concentration device to concentrate the diluted blood. (freepatentsonline.com)
  • 3. The extracorporeal circulation apparatus according to claim 2, wherein said blood supply unit includes a heat exchanger to heat the concentrated blood prior to metering the concentrated blood into a blood vessel of the mammal. (freepatentsonline.com)
  • 4. The extracorporeal circulation apparatus according to claim 3, and further comprising a control device to control said fluid supply pump and said drawing-out/fluid supply pump such that the flow rate of the diluent supplied into the blood vessel of the mammal and the flow rate of blood metered from the mammal can be controlled. (freepatentsonline.com)
  • A newly created antibody protects against blood coagulation in extracorporeal bypass systems without bleeding risk in vivo. (sciencemag.org)
  • A blood flow of 400ml/min is provided by an roller pump of the heart lung machine in a parallel stream to the main circulation. (clinicaltrials.gov)
  • 5. An extracorporeal circulation device comprising the blood supply flow rate controlling device according to any one of Claims 1 to 4. (go.jp)
  • Blood gases and acid-base status are important parameters during extracorporeal circulation. (springer.com)
  • Reliability of a complex model of human acid-base and blood gas status under extracorporeal circulation was evaluated using clinical documentation data. (springer.com)
  • A mathematical model for blood gas and acid-base status under extracorporeal circulation was developed. (springer.com)
  • Modelling the patients' acid-base status and blood gases will be important for further development of control algorithms used in extracorporeal circulation. (springer.com)
  • To evaluate the effect of simple blood contact with plastic tubes in the absence of circulation on neutrophil activation, 80 ml blood obtained from blood donors and anticoagulated with heparin, as described before, was mixed with 90 ml Ringer's lactate solution and used to prime a closed loop of circuit tubing (without an oxygenator) identical to those used for the experiments of simulated CPB. (asahq.org)
  • Physiological coagulation can be maintained in extracorporeal circulation by means of shed blood separation and coating. (semanticscholar.org)
  • Extracorporeal Circulation - Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation. (orcexperts.com)
  • Blood recognizes the extracorporeal circuit surfaces as "foreign", triggering coagulation and inflammatory events that may lead to adverse patient outcomes. (medtronic.com)
  • THERAKOS™ Photopheresis is contraindicated in patients who cannot tolerate extracorporeal volume loss or who have white blood cell counts greater than 25,000 mm3. (pharmiweb.com)
  • It becomes particularly more challenging to maintain this physiologic hemostasis when we are faced with extracorporeal life support therapies, where blood is continuously in contact with a foreign extracorporeal circuit surface predisposing a prothrombotic state. (frontiersin.org)
  • 3. The device according to claim 1, wherein a first gas exchanger as a CO 2 exchanger and a second gas exchanger as an oxygenator are disposed consecutively in the extracorporeal blood path. (google.es)
  • 6. The device according to claim 3, wherein at least one CO 2 sensor, whose signal is connected as an actual value to a main control unit which compares the actual value with a desired value and regulates the gas flow of the first gas exchanger based on the result of the comparison, is provided in the extracorporeal blood path. (google.es)
  • Circulation of blood outside the body. (tabers.com)
  • Nitric oxide (NO) generating (NOGen) materials have been shown previously to create localized increases in NO concentration by the catalytic decomposition of blood S-nitrosothiols (RSNO) via copper (Cu)-containing polymer coatings and may improve extracorporeal circulation (ECC) hemocompatibility. (naver.com)
  • Conclusion: In the cardiac arrest condition, pulsatile extracorporeal circulation provides more blood flow, higher flow velocity and less resistance to coronary artery than non-pulsatile circulation. (elsevier.com)
  • The role of leptin in the acute stress response to extracorporeal circulation has been well documented, however, the relationship between leptin and zinc has not been investigated previously. (nel.edu)
  • These results indicate that circulating leptin levels increase after the extracorporeal circulation as an acute response, while zinc and copper levels decrease at the same period. (nel.edu)
  • Pumpless extracorporeal interventional lung assist in patients with acute respiratory distress syndrome: a prospective pilot study. (springer.com)
  • Extracorporeal life support for severe acute respiratory distress syndrome in adults. (springer.com)
  • Twenty patients who were taken to elective coronary artery bypass grafting operations using extracorporeal circulation were taken to this research and divided into two equal groups (n1, n2). (nel.edu)
  • We studied 100 consecutive patients undergoing elective coronary artery bypass grafting, requiring extracorporeal circulation, and those eligible for a fast-track pathway. (mendeley.com)
  • On May 6, 1953 Gibbon performed his first successful operation using an extracorporeal circuit in an 18-year-old woman who had a large atrial septum defect with a large left-to-right shunt. (wikipedia.org)
  • In this study, we enrolled 50 consecutive newborns, infants, and small children, who underwent extracorporeal circulation circuit with various age of storage RBCs that are used for priming. (thefreedictionary.com)
  • In order to counterbalance this sequence of events and to diminish oxidative injury, several studies have investigated the use of coating materials such as heparin, PMEA, and phosphorylcholine on the surface of Extracorporeal Circulation Circuit (ECC). (thefreedictionary.com)
  • The simulated extracorporeal circuit was set up according to the description of Mellgren et al. (asahq.org)
  • To improve hemocompatibility in an extracorporeal circuit, replication of the anti-thrombotic and anti-inflammatory properties of the endothelium is ideal. (frontiersin.org)
  • Meanwhile, the use of extracorporeal circulation system will lead to excessive activation of the coagulation system. (thefreedictionary.com)
  • This invention provides a method of inhibiting coagulation in extracorporeal circulation in a subject, comprising administration of a therapeutically effective amount of a monoclonal antibody which inhibits the ability of tissue factor to bind to factor VII/VIIa. (google.com)
  • Mechanism of platelets activation during collection is not fully understood.19 Various theories have been put forward to explain the platelet activation during extracorporeal circulation .Exposure of platelets to physical forces and artificial surfaces of the collection set during extracorporeal circulation may result in platelet activation.20 Extracorporeal circulation , i.e. (thefreedictionary.com)
  • Introduction: We report two drowning victims with hypothermic circulatory arrest who were resuscitated with the use of extracorporeal circulation (ECC). (ebscohost.com)
  • Conclusions: In this survival model of hypothermic extracorporeal circulatory support in immature swine, histologic brain injury was similar in piglets subjected to FF, SCP or HCA. (elsevier.com)
  • The use of a Minimall ExtraCorporeal Circulation system (MiECC) tries to eliminate all this side effects. (heartbeat5.nl)
  • A newly created antibody to the active site of Factor XIIa protects against clotting of extracorporeal bypass circuitry without bleeding risk in vivo, obviating the need for heparin (Larsson et al . (sciencemag.org)
  • Sixty consecutive patients were randomized to miniaturized extracorporeal circulation (n = 30) or off-pump coronary revascularization (off-pump coronary artery bypass grafting, n = 30). (unboundmedicine.com)
  • 0001). Hemoglobin levels were significantly higher in the miniaturized extracorporeal circulation group than in the off-pump coronary artery bypass grafting group after 24 hours (P = .01). (unboundmedicine.com)
  • Fondazione Poliambulanza is leader not only in Italy but also in Europe in Coronary artery bypass grafting without extracorporeal circulation with at least a 90 per cents of treatments performed in that procedure, while the average regarding other italian hospitals is about 20 per cent. (poliambulanza.it)
  • Background: Our aim was to investigate the differences in postoperative hearing thresholds in patients undergoing coronary artery bypass grafting with (Group I, n=20) or without (Group II, n=17) extracorporeal circulation. (medeniyet.edu.tr)
  • in both of them cannulation was achieved at a different venous site There were no procedure-related complications and no flow disturbances during the extracorporeal circulation. (minervamedica.it)
  • Before initiating CPB, the lines between the patient and the pump have to be filled as well as the oxygenator and venous reservoir with a priming solution in order to create an air-free, closed circulation system to prevent embolism. (clinicsinsurgery.com)
  • However, careful consideration must be given to psychiatric history and follow-up given the substantial commitment of resources, potential for complications and for stranding patients on extracorporeal therapy without definitive destination therapy. (deepdyve.com)
  • The introduction of extracorporeal circulation has facilitated open heart surgery. (wikipedia.org)
  • Since the beginning of coronary surgery, the Russian physician Kolesov 9 played an important role in myocardial revascularization without extracorporeal circulation. (scielo.br)
  • Extracorporeal circulation (ECC) is an invaluable tool in lung transplantation (lutx). (ovid.com)
  • Filtered air was passed through the oxygenator at 2 l/min, and circulation commenced with a roller pump (Polystan, Vaerlose, Denmark) at a flow rate of 3 l/min for 2 h at 37 [degree sign]C. The perfusate temperature was set at 37 [degree sign]C. Electrolyte, glucose, and hematocrit levels were kept constant during the experiment. (asahq.org)
  • Extracorporeal circulation was maintained for two hours at a pump flow of 2 L/min. (elsevier.com)
  • Clinical cases of normothermic extracorporeal circulation (ECC) are increasing, but the possibility of brain damage is not clear. (umin.ac.jp)
  • Randomized clinical trial of pressure-controlled inverse ratio ventilation and extracorporeal CO2 removal for adult respiratory distress syndrome. (springer.com)
  • The companies will collaborate on translational research to further expand understanding of the underlying mechanism of action (MOA) for extracorporeal photopheresis, and its application toward the development of potential next-generation photopheresis technology, with plans to expand on Mallinckrodt's current THERAKOS™ Photopheresis platform through new clinical trials. (pharmiweb.com)
  • Intracoronary shunt is an alternative for minimizing myocardial ischemia during the myocardial revascularization procedure without extracorporeal circulation 15,16 . (scielo.br)
  • The combination of both, high-standard CTO-PCI and an extracorporeal circulation support system, allows us to pursue the interventional procedure. (thefreedictionary.com)
  • After the procedure, the patient was intubated and extracorporeal circulation was terminated. (dergisi.org)
  • The preliminary free Current Perspectives of the Extracorporeal Circulation 2000 of this everyone sends its online ebook that can move into posts to the outstanding new carousel Neoplasms that more not than never, may check formed to an duplicate trauma work. (steff-schroeder.de)
  • preventable Buddha Sweet Potato Casserole Strong Ale Arrives Sept. Apologies, but the free Current Perspectives of the Extracorporeal Circulation 2000 you did could then skip formed. (steff-schroeder.de)
  • Goetz et al 3 were the first to use an anastomosis of the right internal mammary artery with the right coronary artery without extracorporeal circulation. (scielo.br)
  • To assess the immediate postoperative period of patients undergoing myocardial revascularization without extracorporeal circulation with different types of grafts. (scielo.br)
  • Myocardial revascularization without extracorporeal circulation was performed in 112 patients. (scielo.br)
  • Myocardial revascularization without extracorporeal circulation is a reproducible technique that is an alternative for treating ischemic heart disease. (scielo.br)
  • At the beginning, myocardial revascularization without extracorporeal circulation was used to treat single-vessel lesions in critically ill patients 13-15 . (scielo.br)
  • Extracorporeal Life Support Organization Patient Specific Guidelines. (springer.com)