DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
Extracorporeal CirculationOxygenatorsHeart, ArtificialCardiopulmonary BypassHeart-Lung MachineCardiac Surgical ProceduresOxygenators, MembraneHeart Arrest, InducedRewarmingHypothermia, InducedCoronary Artery BypassSystemic Inflammatory Response SyndromeAntigens, CD11Aminocaproic AcidThoracic SurgeryPostoperative PeriodExtracorporeal Membrane OxygenationMyocardial RevascularizationAprotininCoronary Artery Bypass, Off-PumpBlood TransfusionTreatment OutcomeMonitoring, IntraoperativePlatelet ActivationPostoperative ComplicationsAntifibrinolytic AgentsThoracotomyTime FactorsBlood CirculationHeart Valve Prosthesis ImplantationHemodynamicsEquipment DesignAortic Aneurysm, ThoracicHemolysisSerine Proteinase Inhibitors
Extracorporeal Circulation
Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation.
Oxygenators
Devices which mechanically oxygenate venous blood extracorporeally. They are used in combination with one or more pumps for maintaining circulation during open heart surgery and for assisting the circulation in patients seriously ill with some cardiac and pulmonary disorders. (UMDNS, 1999)
Heart, Artificial
A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)
Cardiopulmonary Bypass
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
Heart-Lung Machine
Apparatus that provides mechanical circulatory support during open-heart surgery, by passing the heart to facilitate surgery on the organ. The basic function of the machine is to oxygenate the body's venous supply of blood and then pump it back into the arterial system. The machine also provides intracardiac suction, filtration, and temperature control. Some of the more important components of these machines include pumps, oxygenators, temperature regulators, and filters. (UMDNS, 1999)
Cardiac Surgical Procedures
Surgery performed on the heart.
Oxygenators, Membrane
Devices in which blood and oxygen are separated by a semipermeable membrane, generally of Teflon or polypropylene, across which gas exchange occurs. The membrane may be arranged as a series of parallel plates or as a number of hollow fibers; in the latter arrangement, the blood may flow inside the fibers, which are surrounded by gas, or the blood may flow outside the fibers and the gas inside the fibers. (Dorland, 28th ed)
Heart Arrest, Induced
A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).
Rewarming
Application of heat to correct hypothermia, accidental or induced.
Hypothermia, Induced
Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.
Coronary Artery Bypass
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Systemic Inflammatory Response Syndrome
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA 90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
Antigens, CD11
A group of three different alpha chains (CD11a, CD11b, CD11c) that are associated with an invariant CD18 beta chain (ANTIGENS, CD18). The three resulting leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE ADHESION) are LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MACROPHAGE-1 ANTIGEN; and ANTIGEN, P150,95.
Aminocaproic Acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Thoracic Surgery
A surgical specialty concerned with diagnosis and treatment of disorders of the heart, lungs, and esophagus. Two major types of thoracic surgery are classified as pulmonary and cardiovascular.
Postoperative Period
The period following a surgical operation.
Extracorporeal Membrane Oxygenation
Application of a life support system that circulates the blood through an oxygenating system, which may consist of a pump, a membrane oxygenator, and a heat exchanger. Examples of its use are to assist victims of smoke inhalation injury, respiratory failure, and cardiac failure.
Myocardial Revascularization
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
Aprotinin
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
Coronary Artery Bypass, Off-Pump
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
Blood Transfusion
The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)
Treatment Outcome
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Monitoring, Intraoperative
The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).
Platelet Activation
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
Postoperative Complications
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Antifibrinolytic Agents
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
Thoracotomy
Surgical incision into the chest wall.
Time Factors
Elements of limited time intervals, contributing to particular results or situations.
Blood Circulation
The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
Heart Valve Prosthesis Implantation
Surgical insertion of synthetic material to repair injured or diseased heart valves.
Hemodynamics
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Equipment Design
Methods of creating machines and devices.
Aortic Aneurysm, Thoracic
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Hemolysis
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
Serine Proteinase Inhibitors
Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.

Validation of haemodialysis recirculation and access blood flow measured by thermodilution. (1/380)

BACKGROUND: Recirculation (R) and access blood flow (Qac) measurements are considered useful indicators of adequate delivery of haemodialysis. It was the purpose of this study to compare measurements of R and Qac obtained by two different techniques which are based on the same principle of indicator dilution, but which differ because of the characteristics of the injection and detection of the different indicators used. METHODS: Recirculation measured by a thermal dilution technique using temperature sensors (BTM, Fresenius Medical Care) was compared with recirculation measured by a validated saline dilution technique using ultrasonic transducers placed on arterial and venous segments of the extracorporeal circulation (HDM, Transonic Systems, Inc.). Calculated access flows were compared by Bland Altman analysis. Data are given as mean +/- SD. RESULTS: A total of 104 measurements obtained in 52 treatments (17 patients, 18 accesses) were compared. Recirculation measured with correct placement of blood lines and corrected for the effect of cardiopulmonary recirculation using the 'double recirculation technique' was -0.02 +/- 0.14% by the BTM technique and not different from the 0% measured by the HDM technique. Recirculation measured with reversed placement of blood lines and corrected for the effect of cardiopulmonary recirculation was 19.66 +/- 10.77% measured by the BTM technique compared with 20.87 +/- 11.64% measured by the HDM technique. The difference between techniques was small (-1.21 +/- 2.44%) albeit significant. Access flow calculated from BTM recirculation was 1328 +/- 627 ml/min compared with 1390 +/- 657 ml/min calculated by the HDM technique. There was no bias between techniques. CONCLUSION: BTM thermodilution yields results which are consistent with the HDM ultrasound dilution technique with regard to both recirculation and access flow measurement.  (+info)

Extracorporeal rheopheresis in the treatment of acute ischemic stroke: A randomized pilot study. (2/380)

BACKGROUND AND PURPOSE: Extracorporeal rheopheresis is a safe method to optimize hemorheology. Our aim was to determine whether treatment with extracorporeal rheopheresis in patients with acute ischemic hemispheric stroke improves cerebral perfusion as assessed with serial 99mTc-ethyl-cysteinate-dimer single-photon emission CT (99mTc-ECD SPECT). We also investigated how clinical outcome is associated with treatment and imaging results. METHODS: Thirty-three patients (mean age, 64+/-10 years) with acute ischemic hemispheric stroke were included in a prospective, randomized, parallel group pilot study. First treatment with or without extracorporeal rheopheresis took place within 12 hours after the onset of symptoms and was repeated 3 times at intervals of 24 hours. Hemorheological parameters were measured before and after each session. Each patient underwent 99mTc-ECD SPECT immediately before treatment, 6 to 8 hours after treatment, and after 5 days. A semiquantitative SPECT graded scale was used to measure depth and extent of activity deficits and thus to quantify the perfusion deficit. RESULTS: Seventeen patients were actively treated with extracorporeal rheopheresis, and 16 patients did not receive extracorporeal rheopheresis. After 3 months, no differences were found in the functional or neurological outcome. Despite a rapid, sustained decrease of plasma viscosity and erythrocyte aggregation in the rheopheresis group, there was no significant difference in the SPECT graded scale after therapy between the 2 groups. Patients with early reperfusion (decrease in the SPECT graded scale >25% 6 to 8 hours after therapy compared with the baseline examination) experienced a better functional outcome (Modified Rankin Scale) after 3 months compared with patients without reperfusion (P=0.04). CONCLUSIONS: Since quantitative flow mapping and clinical follow-up did not reveal any differences between patients who were treated with extracorporeal rheopheresis and controls, it appears very unlikely that extracorporeal rheopheresis enhances reperfusion after acute cerebral ischemia.  (+info)

The effects of extracorporeal whole body hyperthermia on the functional and phenotypic features of canine peripheral blood mononuclear cells (PBMC). (3/380)

In this study the effect of transient 42.3 degrees C whole body hyperthermia (WBH) on the distribution of PBMC phenotypes and in vitro blastogenic responsiveness was determined in dogs. Hyperthermia (n = 6) was induced by heating venous blood during extracorporeal circulation (venous perfusion WBH); perfused non-heated dogs (n = 4) were used as controls. Both euthermic and hyperthermic perfusion produced transient lymphopenia which normalized in controls after perfusion but persisted in hyperthermic animals throughout the 8-day post-perfusion observation interval. The transient lymphopenia in control dogs was non-selective. In contrast, WBH-associated lymphopenia was selective, in that CD5+ T lymphocytes were more sensitive to hyperthermia than sIg+ B cells and, within the T cell compartment, suppressor (CD8+) cells were more sensitive to hyperthermic stress than helper (CD4+) lymphocytes. Functional analyses showed that WBH caused persistent suppression of PBMC blastogenesis in response to T cell phytomitogens. Increased plasma cortisol levels were correlated to peak lymphopenia and hyporesponsiveness to phytomitogens. Despite these alterations, high grade WBH was well tolerated and there was no evidence of opportunistic infection.  (+info)

Coating of extracorporeal circuit with heparin does not prevent sequestration of propofol in vitro. (4/380)

Propofol is sequestered in extracorporeal circuits, but the factors responsible for the phenomenon are mostly unknown. We have compared two extracorporeal circuits (oxygenators, reservoirs and tubings) coated with heparin with two corresponding uncoated circuits for their capacity to sequester propofol in vitro. Three experiments were conducted with each circuit. The circuit was primed with a mixture of Ringer's acetate solution and whole blood, and the study conditions (pump flow, temperature, pH) were standardized. Propofol was added to the solution to achieve a concentration of 2 micrograms ml-1. These studies were followed with concentrations of 10- and 100-fold to assess possible saturation of propofol binding. Serial samples were obtained from the circulating solution for measurement of propofol concentration. Propofol concentrations decreased to 22-32% of the initial predicted concentration of 2 micrograms ml-1 in the circuits (no significant difference between circuits). With greater concentrations, the circuits did not become saturated with propofol, even with the highest predicted concentration of 200 micrograms ml-1. We conclude that propofol was sequestered in extracorporeal circuits in vitro, irrespective of coating the circuit with heparin.  (+info)

Metabolism of radioiodinated fatty acid analogs in ischemic and hypoxic canine myocardium. (5/380)

Myocardial metabolism of 17-[123I]-iodoheptadecanoic acid (IHDA), 15-(p-[131I]-iodophenyl)pentadecanoic acid (pIPPA) and 15-(p-[125I]-iodophenyl)-3,3-dimethylpentadecanoic acid (DMIPP) was assessed during ischemia and hypoxia. The simultaneous investigation allowed us to evaluate differences in metabolic handling of these three fatty acids. METHODS: In 17 open-chest dogs, the left ascending coronary artery was cannulated and extracorporeal bypass (ECB) perfused. In 3 dogs, ECB flow was kept normal, and these control experiments showed that kinetics of the radioiodinated fatty acids were not affected by the ECB technique itself. In 9 dogs, ECB flow was reduced to one third (ischemia), and in 5 dogs, the ECB area was perfused with venous blood and was kept at control values (hypoxia). After simultaneous intravenous injection of IHDA, pIPPA and DMIPP, seven paired biopsy specimens from the native and ECB-perfused myocardium were taken over an assay period of 35 min. Total activity and the distribution in the aqueous phase and lipid fractions were determined, and time-activity curves were constructed. RESULTS: In ischemic (Is) but not in hypoxic (Hy) myocardium, peak total activity of IHDA, pIPPA and DMIPP decreased significantly versus normal (N) myocardium (IHDA: N = 700 +/- 267 versus Is = 335 +/- 158 dpm/mg/mCi; pIPPA: N = 988 +/- 318 versus Is = 438 +/- 180 dpm/mg/mCi; DMIPP: N = 352 +/- 146 versus Is = 179 +/- 82 dpm/mg/mCi; all P values < 0.001). The relative decrease was similar for IHDA, pIPPA or DMIPP. Half-time values of total activity were prolonged for IHDA and pIPPA but were shortened for DMIPP in ischemic and hypoxic myocardium (IHDA: N = 22, Is = 44 and Hy = 50 min; pIPPA: N = 24, Is = 95 and Hy = 169 min; DMIPP: N = 528, Is = 409 and Hy = 115 min). The aqueous phase activity for IHDA, pIPPA and DMIPP decreased significantly versus normal myocardium in both ischemic (IHDA: N = 71% +/- 9% versus Is = 36% +/- 9%, P < 0.001; pIPPA: N = 62% +/- 10% versus Is = 25% +/- 8%, P < 0.001; DMIPP: N = 26% +/- 11% versus Is = 18% +/- 3%, P < 0.05) and hypoxic (IHDA: N = 76% +/- 8% versus Hy = 62% +/- 8%, P < 0.05; pIPPA: N = 66% +/- 8% versus Hy = 46% +/- 10%, P < 0.05; DMIPP: N = 32% +/- 6% versus Hy = 24% +/- 4%, P < 0.05) myocardium. The relative decrease was significantly highest for pIPPA and lowest for DMIPP. Incorporation into triacylglycerols increased significantly for IHDA, pIPPA and DMIPP in both ischemic and hypoxic myocardium. In normal myocardium, DMIPP was already mainly incorporated into triacylglycerols. Activity of IHDA and pIPPA in acylcarnitine increased significantly in ischemic and hypoxic myocardium. CONCLUSION: Kinetics of the radioiodinated fatty acid analogs in myocardium are altered during oxygen deprivation in a similar fashion as documented in literature for natural fatty acids. However, the changes were different between IHDA, pIPPA and DMIPP, suggesting different metabolic handling and thus reflecting different aspects of myocardial fatty acid metabolism.  (+info)

Role of C3 cleavage in monocyte activation during extracorporeal circulation. (6/380)

BACKGROUND: We previously demonstrated that inhibiting formation of terminal complement components (C5a and C5b-9) prevents platelet and neutrophil (PMN) but not monocyte activation during simulated extracorporeal circulation (SECC). This study examined whether earlier complement inhibition during SECC, blocking C3a formation, would additionally prevent monocyte activation. METHODS AND RESULTS: SECC was established by recirculating heparinized whole blood from human volunteers on a membrane oxygenator. CAB-2, a chimeric protein constructed from genes encoding the complement regulatory proteins CD46 and CD55, inactivates the C3/C5 convertases and blocks in vitro generation of C3a, C5a, and C5b-9. CAB-2 was used in 4 experiments at a final concentration of 300 micrograms/mL and 4 experiments at 30 micrograms/mL; 4 control runs used vehicle alone. Samples were assayed for C3a and C5b-9, monocyte activation (CD11b upregulation), PMN activation (CD11b upregulation and elastase release), and platelet activation (P-selectin expression and monocyte-platelet conjugate formation). CAB-2 at both doses significantly inhibited formation of C3a and C5b-9 during SECC. High-dose CAB-2 significantly blocked monocyte and PMN CD11b upregulation and PMN elastase release. CAB-2 also inhibited formation of platelet activation-dependent monocyte-platelet conjugates. CONCLUSIONS: Blockade of complement activation early in the common pathway inhibited monocyte CD11b upregulation during SECC, suggesting that early complement components contribute most to monocyte activation during SECC. As expected, PMN and platelet activation were blocked by terminal complement inhibition. This investigation further elucidates the relation between complement and blood cell activation during simulated cardiopulmonary bypass.  (+info)

Nitric oxide does not modulate the increases in blood flow, O2 consumption, or contractility during CaCl2 administration in canine hearts. (7/380)

OBJECTIVE: Endothelium-derived nitric oxide (EDNO) has been shown to have vascular, metabolic, and contractile effects in the heart. We evaluated these effects during intracoronary (i.c.) administration of CaCl2 in dogs. METHODS: The left anterior descending coronary artery of nine anesthetized, open-chest dogs was perfused at controlled pressure (80 mm Hg) with arterial blood. Coronary blood flow (CBF) was measured with a Doppler transducer and segmental shortening (SS) with ultrasonic crystals. Myocardial oxygen consumption (MVO2) and oxygen extraction (EO2) were calculated. Responses were assessed during i.c. infusions of CaCl2 (5, 10, 15 mg min-1) before and after administration of the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME; 300 micrograms min-1 for 15 min, i.c.). RESULTS: Before L-NAME, CaCl2 caused dose-dependent, proportional increases in SS and MVO2. Although CBF also increased, these responses were less than proportional to those in MVO2, and thus EO2 increased. L-NAME did not alter the cardiac effects of CaCl2. CONCLUSIONS: (1) CaCl2 had direct inotropic and coronary vasoconstricting effects. (2) The vasoconstricting effect impaired coupling of CBF to the augmented metabolic demands by local vasodilating mechanisms. (3) EDNO did not modulate the increases in CBF, MVO2, or SS during administration of CaCl2.  (+info)

A new method of intraoperative hydraulic impedance measurement provides valuable prognostic information about infrainguinal graft patency. (8/380)

PURPOSE: Prognostic information about graft outcome, obtained by using a new method for intraoperative measurement of vascular impedance, was evaluated. METHODS: Hydraulic impedance was measured in 136 infrainguinal bypass grafts that were entered into a multicenter trial. Seventy femoropopliteal and 66 femorocrural polytetrafluoroethylene (PTFE) grafts were used. The arterial impedance measurement involved a silicon bypass graft temporarily inserted between the proximal and distal anastomoses sites. A flowmeter probe and a pressure transducer were incorporated into the tube. The digitally stored waveforms were subjected to a fast Fourier transformation and both input (Z(x)) and characteristic (Z(0)) impedances, as well as phase relations, were computed and related to graft outcome after 3 years. RESULTS: Significant prognostic information for both popliteal and crural grafts was provided by means of the phase angle of the first harmonic. Primary and secondary patency rates for popliteal bypasses were 45% +/- 1% and 65% +/- 2% for phase angles greater than -40 degrees (n = 57) and 37% +/- 1% and 40% +/- 1% for phase angles less than -40 degrees (n = 13, p(prim ) = not significant, p(sec) < 0.01). For crural grafts, the secondary patency rates were 49% +/- 1% and 61% +/- 2% for phase angles greater than -40 degrees (n = 53) and 15% +/- 1% and 0% for phase angles less than -40 degrees (n = 13, P <.01). All crural bypass grafts with phase angles less than -40 degrees occluded within 16 months. Steady flow resistance, as well as Z(x) and Z(0), failed to indicate a significant relation to graft prognosis. CONCLUSION: This method provides reliable prognostic information regarding graft patency and opens hydraulic impedance measurement to clinical surgery. The phase lag between flow and pressure curves, as expressed by the phase angle of the first harmonic, provides significant prognostic information.  (+info)

Patent US2659368 - Extracorporeal circulation device - Google PatentsPatent US2659368 - Extracorporeal circulation device - Google Patents
NovTT7, 1953 J. H. GIBBON, JR, ETAL ,368 EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 1 INVENTORS .hmv bf Gaga/1.17., wrnv MA. Mamas ATTORNEY J. H. GIBBON, JR, ETAL 2,659,368 EXTRACORPOREAL CIRCULATION DEVICE Nov. 17, 1953 16 Sheets-Sheet 2 Filed May 28, 1949 Nov. 17, 1953 J. H. GIBBON, JR, ET AL I EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 5 FIG. 5 FIG? 5 mm H {R Tfll N R i m mu .T Q W MZ Mm? W my 4 m Nov. 17, 1953 J. H. GIBBON, JR., ET AL 2,559,368 EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 6 INVENTORS la/w 1% 67.950 J2, Gus/7w K17. MAI/V845 Jo/r/v A [was/Away; Kama/v a A [max/9.1;. ATTORNEY Nov. 17, 1953 J. H. GIBBON,IJR., ET AL v ,3 8 EXTRACORPOREAL CIRCULATION DEVICE (Z FIG. 22 z 14;: 1: /9.9 1 f I: I \ FIG. 51 m0 .FIG. IO NTORS FFMXM ATTORNEY Nov. 17, 1953 J. H. GIBBON, JR, ET AL EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 8 INVENTORS wrnv K4. Mum/Pas, 42 (FF/10,70 A flaws/P Jm FIG. ...
http://www.google.com/patents/US2659368?dq=assignee:+google
Download Principles of Miniaturized Extracorporeal Circulation - Kyriakos Anastasiadis pdf
Minimal extracorporeal circulation (MECC) systems have been designed in order to reduce dramatically the side-effects of conventional extracorporeal circulation
http://medical-ebooks.net/39671-download-principles-of-miniaturized-extracorporeal-pdf/
High-Dose Radioimmunotherapy Combined With Extracorporeal Depletion in a Syngeneic Rat Tumor Model | MAD for CancerHigh-Dose Radioimmunotherapy Combined With Extracorporeal Depletion in a Syngeneic Rat Tumor Model | MAD for Cancer
BACKGROUND: The aim of the current study was to investigate the possibility of increasing the maximal tolerated dose (MTD) of a tumor-selective radiolabeled antibody when radioimmunotherapy (RIT) is combined with extracorporeal depletion of radioimmunoconjugates from the circulation. Furthermore, the authors evaluated whether this increase in dose improved the therapeutic effect on solid manifest tumors in an immunocompetent animal model. METHODS: Rats were injected with high activities/body weight of lutetium (Lu-177)- or yttrium (Y-90)-labeled antibody conjugates (monoclonal antibody tetraazacyclododecanetetraacetic acid-biotin) and subjected to removal of the conjugate from the circulation by extracorporeal affinity adsorption treatment 24 hours postinjection. Myelotoxicity was assessed by analysis of blood parameters for 12 weeks. The effect of increased doses in combination with extracorporeal affinity adsorption treatment was evaluated with respect to myelotoxicity and therapeutic effect ...
https://www.madforcancer.lu.se/sven-erik-strand/publication/b92f2ae8-0866-4f92-9e2c-798978a92649
Evaluation of a mathematical model for blood gases and acid-base status during extracorporeal circulation | Springer for...Evaluation of a mathematical model for blood gases and acid-base status during extracorporeal circulation | Springer for...
A mathematical model for blood gas and acid-base status under extracorporeal circulation was developed. This model consists of a multiple compartment model for the oxygenator, and models for arterial and venous PCO2, PO2, (including temperature- and pH-dependent shift in oxygen-binding capacity of haemoglobin), SO2, bicarbonate, base excess and pH. It was implemented in a Matlab/Simulink environment. Input parameters were oxygenator type, gas flow, FiO2, arterial pump flow, temperature, haemoglobin concentration and haematocrit. As output parameters, venous and arterial SO2, PO2, PCO2 and pH were analyzed. The model was tested by using clinical monitoring data during extracorporeal circulation of patients undergoing aorto-coronary bypass grafting as input data, and comparing the model output with the results of conventional blood gas analyses (Rapidlab 288®) retrospectively. ...
https://rd.springer.com/article/10.1186/cc2153
Minimal ExtraCorporeal Circulation (MiECC) - Heartbeat - dutch perfusion serviceMinimal ExtraCorporeal Circulation (MiECC) - Heartbeat - dutch perfusion service
The MiECC is a closed system, without a venous reservoir, so blood will be most of the time inside the patient instead of in an open cardiotomy reservoir.. The centrifugal pump will provide an active venous drainage of the patient. The negative pressure that a centrifugal pump can create is limited at -60 mmHg. The system is used with the Califiore bloodcardioplegia technique.. The total priming volume of the system can be further reduced by autologous blood priming. The aim is a small and biocompatible system, what should lead to minimal heamodilution, reduced blood transfusion, reduced inflammatory response and reduced the amount of haemolysis.. The systemic heparinization can be reduced to 1,5 mg/kg body weight, activated clotting times of 300 sec and more are common in this technique.. The MiECC has a specific oxygenator with diffuse fibres, it is not possible to give anaesthetic gas over this system.. ...
https://www.heartbeat5.nl/mecc-miecc/
Patente US6129656 - Extracorporeal blood processing methods and apparatus - Google PatentesPatente US6129656 - Extracorporeal blood processing methods and apparatus - Google Patentes
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
http://www.google.es/patents/US6129656?dq=flatulence
Correlation Between Access Blood Flow and Extracorporeal Blood Flow - Full Text View - ClinicalTrials.govCorrelation Between Access Blood Flow and Extracorporeal Blood Flow - Full Text View - ClinicalTrials.gov
Accesses that show a large (,15%) decrement over time in vascular access blood flow are associated with a high risk of thrombosis. Serial measurements of vascular access blood flow predict access thrombosis. At the moment, the measurement of access flow is time consuming, operator dependent, so that it cannot be done with every treatment. We hypothesized that extracorporeal blood flow at pressure of -200 to -260 mmHg in arterial line has correlation with access blood flow and this can be used to estimate access blood flow ...
https://clinicaltrials.gov/ct2/show/NCT00522704?cond=%22Arteriovenous+Fistula%22&rank=8
Patent US20060224099 - Control system for driving fluids through an extracorporeal blood circuit - Google PatentsPatent US20060224099 - Control system for driving fluids through an extracorporeal blood circuit - Google Patents
A control deck and system for controlling and driving blood fluids through an extracorporeal blood circuit kit. In one aspect, the invention is a deck having an improved mechanism for securing a cassette in place during treatment operations. The improved deck comprises catches for slidably receiving tabs of the cassette and one or more rotating clamps for locking and securing the cassette in a loaded position. In another aspect the invention is a system for controlling and driving blood fluids having infrared communication abilities to transmit and receive real time data. In still another aspect, the invention is a system for controlling and driving blood fluids having an upright tower design that reduces the footprint of the system. In this embodiment, a centrifuge chamber is positioned in an upper portion of the system while the control deck and photoactivation chamber are located in a base portion of the system.
http://www.google.ca/patents/US20060224099
Kit and method for converting water circulation system to water circulation and purification system - KING JOSEPH A.Kit and method for converting water circulation system to water circulation and purification system - KING JOSEPH A.
A kit for converting a water circulation system in a hot tub into a water purification system including a housing that can be fixedly mounted to a spa or hot tub, a chamber in the housing, an inlet fo
http://www.freepatentsonline.com/6328900.html
Patent US3661262 - Filtration and circulation system for maintaining water quality in ... - Google PatentsPatent US3661262 - Filtration and circulation system for maintaining water quality in ... - Google Patents
A filtration and circulation system for maintaining the water quality in a fish tank favorable for promoting the production and growth of fish therein and for circulating water therethrough at a rate designed to provide a high rate of water exchange in the tank. The system includes particulate, biological and activated charcoal filters serially arranged in pressurized and unpressurized sections thereof for converting or removing ammonia, waste food and excrement from the water. In addition, parallel flow paths from these filters through a protein skimmer and an ultraviolet sterilizer section, respectively, are provided for lower volume treatment of the water being circulated therethrough.
http://www.google.co.uk/patents/US3661262
Biology - The circulation System | Mind Map - MindMasterBiology - The circulation System | Mind Map - MindMaster
A mind map about biology - the circulation system. You can edit this mind map or create your own using our free cloud based mind map maker.
https://www.mindmaster.io/mind-maps/10733/biology-the-circulation-system
Natural Temperature Decrease Extracorporeal Circulation for Cases at High Risk of Brain Damage
Clinical cases of normothermic extracorporeal circulation (ECC) are increasing, but the possibility of brain damage is not clear. In emergencies, the brain protective effects of mild (33-34 ) hypothermic therapy have been clearly confirmed. Natural Temperature decrease ECC was conducted in this study, hoping to obtain the advantages of both normothermic ECC and brain protection by mild hypothermia. These were 12 cases at high risk of brain damage (10 cases of brain infarction and 2 cases of severe carotid artery stenosis). In all cases, coronary artery bypass grafting operation with natural temperature decrease ECC was performed. The average laryngeal temperature dropped to 33.0 }0.3 . There was no brain infarction or ICU syndrome. Evaluation of post-operative brain condition by the patients themselves and their families was good. The possibility of natural temperature decrease ECC for high risk cases of brain damage was demonstrated ...
http://square.umin.ac.jp/jscvs/eng/journal/vol29-4/254.html
Oxidative stress during extracorporeal circulation | USC Research Bank - University of the Sunshine CoastOxidative stress during extracorporeal circulation | USC Research Bank - University of the Sunshine Coast
There is an increased oxidative stress response in patients having cardiac surgery, haemodialysis or extracorporeal membrane oxygenation that is related to poorer outcomes and increased mortality. Exposure of the patients blood to the artificial surfaces of these extracorporeal devices, coupled with inflammatory responses, hyperoxia and the pathophysiological aspects of the underlying illness itself, all contribute to this oxidative stress response. Oxidative stress occurs when there is a disruption of redox signalling and loss of control of redox balance. Ongoing oxidative stress occurring during extracorporeal circulation (ECC) results in damage to lipids, proteins and DNA and contributes to morbidity and mortality. This review discusses reactive species generation and the potential clinical consequences of oxidative stress during ECC as well as provides an overview of some current antioxidant compounds that are available to potentially mitigate the oxidative stress response.
http://research.usc.edu.au/vital/access/manager/Repository/usc:12318
Pulsatile extracorporeal circulation during on-pump cardiac surgery enhances aortic wall shear stress.
Controversy on superiority of pulsatile versus non-pulsatile extracorporeal circulation in cardiac surgery still continues. Stroke as one of the major adverse events during cardiopulmonary bypass is, in the majority of cases, caused by mobilization o
http://www.biomedsearch.com/nih/Pulsatile-extracorporeal-circulation-during-pump/22035639.html
Trillium(TM) biopassive surface: A new biocompatible treatment for extracorporeal circulation circuits<...
TY - JOUR. T1 - Trillium(TM) biopassive surface. T2 - A new biocompatible treatment for extracorporeal circulation circuits. AU - Cazzaniga, A.. AU - Ranucci, M.. AU - Isgrò, G.. AU - Soro, G.. AU - De Benedetti, D.. AU - Corradi, R.. AU - Gardinali, M.. PY - 2000/5. Y1 - 2000/5. N2 - 139 patients undergoing cardiac surgery were included in a prospective, randomized trial. Patients were randomly allocated to receive cardiopulmonary bypass (CPB) with Trillium(TM) Biopassive Surface (TBS Group) coated oxygenators or conventional circuits (control group). 112 patients were studied with respect to postoperative biochemical profile; a subgroup of 27 patients was studied with respect to perioperative complement (C3a) activation. Patients in the TBS group demonstrated a significantly lower white blood cell count at the end of the operation (p=0.036) and a significantly higher platelet count the day after the operation (p=0.023) when compared to the control group. C3a was significantly higher (p=0.02) ...
https://moh-it.pure.elsevier.com/en/publications/trilliumtm-biopassive-surface-a-new-biocompatible-treatment-for-e
Extracorporeal Circulation Expert for Consulting, Expert WitnessExtracorporeal Circulation Expert for Consulting, Expert Witness
Experts available for extracorporeal circulation consulting, expert witness, or analyst services for business, legal, and technical professionals.
http://www1.orcexperts.com/experts.asp?strSearchType=all&strQuery=extracorporeal+circulation
No cases of infection observed at the MUHC related to the use of heater-cooler devices during open-heart surgery | McGill...No cases of infection observed at the MUHC related to the use of heater-cooler devices during open-heart surgery | McGill...
Yesterday, the Montreal Heart Institute (MHI) advised its patients, who have undergone open-heart surgery, that there is a very small risk of bacterial infection associated from certain machines (heater-cooler devices) used during heart surgeries that require extracorporeal blood circulation. The heater-cooler devices in question, which are used in many hospitals throughout North America and Europe, may have been contaminated with the bacteria Mycobacterium chimaera during their manufacture in Germany.. At present, we have no evidence that the heater-cooler devices used at the MUHC are contaminated by the bacteria associated with the infections. No cases of such an infection have been observed in our institution following the surgeries practiced at the MUHC. All cleaning and disinfection measures recommended by the manufacturer, as well as quality controls, are in place at the MUHC and are being carefully observed.. It is important to note that transmission of the bacteria in question occurs ...
https://muhc.ca/newsroom/news/no-cases-infection-observed-muhc-related-use-heater-cooler-devices-during-open-heart-surgery
Guidance for Extracorporeal Blood Circuit Defoamer - 510(k) Submissions - Final Guidance for Industry and FDA | FDAGuidance for Extracorporeal Blood Circuit Defoamer - 510(k) Submissions - Final Guidance for Industry and FDA | FDA
Describes a means by which cardiopulmonary bypass defoamer devices may comply with the requirement of special controls for class II devices.
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/guidance-extracorporeal-blood-circuit-defoamer-510k-submissions-final-guidance-industry-and-fda
当归补血汤 Angelicae Circulation Soup当归补血汤 Angelicae Circulation Soup
材料. 当归，北耆，川芎，玉竹，红枣，党参. 可供素食. 保存方法:置于冰箱中冷藏. 净重: 75g. Additional Info. What exactly is it with the necessity to increase blood circulation or mores to the stage, what it really blood circulation exactly? Well, place in laymans terms, its this is the movement of blood with the body. A little more detail is the fact that blood circulation happens when the blood moves round the body inside what is known the blood circulation system. The blood circulation system consists of blood ships (otherwise known as arterial blood vessels), veins and capillary vessels. Our heart continuously pumps the blood through our ships before the day we die or encounter serious problems.. A few of the common signs and symptoms of poor blood circulation can include tingling sensation or numbness of either hands or ft (also known as Neuropathy) a difficulty breathing insufficient energy irregular heartbeats difficulty in remembering things and ...
http://www.chengwoh.com/product/%E5%BD%93%E5%BD%92%E8%A1%A5%E8%A1%80%E6%B1%A4-angelicae-circulation-soup
Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation - Full...Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation - Full...
Despite improvements in the biocompatibility of cardiopulmonary bypass (CPB) circuits, the activation of inflammatory systemic response can result in clinically relevant organ dysfunction. Regarding the central nervous system, prolonged hypoperfusion and microembolization during conventional CPB have been related to postoperative neurologic impairment with an incidence varying from 30% to 60%. This clinical scenario covers a spectrum from a transient subtle cognitive dysfunction to a permanent stroke. Postoperative cognitive decline (POCD) is characterized as impairment in attention, cognition, recognition, orientation, memory, and learning. It may result in prolonged hospitalization, increased morbidity and mortality, while it has an adverse impact on quality of life after surgery.. Near-infrared spectroscopy (NIRS) provides a continuous and noninvasive monitoring of regional cerebral oxygen saturation (rSO2). Recent studies have shown a significant relationship between intraoperative cerebral ...
https://clinicaltrials.gov/ct2/show/NCT01213511?recr=Open&cond=%22Coronary+Artery+Bypass%22&rank=2
Scuba quiz: circulation system
B. False. Answers: Circulation. 1. A. True. The blood supply to the heart, efficiency of its muscle contractions, changes in rate and rhythm and increased work load all result from diving. Such stresses can be tolerated by a healthy heart, but can cause a heart attack in those with coronary problems. A person with any heart disorder should not dive unless cleared by both a cardiologist and a diving physician.. 2. B. False. The blood carries nearly as much oxygen as it can at all times. The change that takes place with exercise is in the circulation of the blood, which is increased to get oxygen to and waste products from tissues more quickly. Increased oxygen partial pressure while diving does allow more oxygen to be carried dissolved in the blood, but the benefit of this is offset by other cardiovascular changes.. 3. B. False. The carotid sinuses, located at the bifurcation of the arteries on each side of the neck, are sensors for blood pressure and provide information to the brain to control ...
http://spofitaholic.com/scuba-quiz-circulation-system/
FPs Air Circulation System I - Fungi.comFPs Air Circulation System I - Fungi.com
Experienced cultivators understand the critical role air circulation plays in the successful growing of mushrooms. Without proper air input and distribution, there is little chance …
http://www.fungi.com/product-detail/product/air-circulation-system-i.html
Asucena Francois
Under the tongue, we as a whole have a mucous film. Mucous films are thin layers of tissue that line depressions in the body and spread the outside of our organs. Some mucous layers do as the name proposes, and discharge bodily fluid-like the films that line the nose.. These films are slightly contrasted with skin, which has numerous layers. Underneath is a free layer of connective tissue, in addition to loads of little vessels. Head to a mirror and investigate your tongue, and youll see a few.. When you hold CBD under your tongue, the dynamic mixes in the arrangement are consumed through the mucous layer and enter the circulation system. Its through the circulation system that they, at that point, access your endocannabinoid framework and each other aspect of your body.read more about holding CBD under Tongue at shorturl.at/ioCHV. You wont see the entirety of the oil retain into your mucous film and vanish, however. For that to occur, youd need to hold up quite a while. After a set measure ...
https://www.wefeedyourhead.com/author/asucena-francois/
Gluta White Capsule / Glutathione / Ivory Capsule /GlutaMax | Full review in Urdu-Call:0336-6541245 - My Anti Aging Beauty
WHAT IS GLUTATHIONE?. Glutathione is a cell reinforcement produced using glycine, glutamic corrosive and cysteine. Researcher view it as a standout amongst the most capable cancer prevention agents. While Glutathione is readied like any restorative or vitamin item - in a sheltered, sterile lab setting - it is made of all-characteristic amino acids that happen in nature and are advantageous to our bodies.. skin-whitening-products-in-pakista. Walnuts, avocados, tomatoes and oranges can all keep Glutathione levels high in the circulation system, however they wont really work to brighten your skin and, add to solid skin - particularly walnuts and avocados, which are additionally high in fundamental unsaturated fats.. Glutathione is by and large taken by means of intravenous injection, under the watchful supervision of a specialist dermatologist. Numerous dermatologists suggest Glutathione injections since they get 100-percent of the measurements into your circulation system. However the nature of ...
https://myantiagingbeauty.com/gluta-white-capsule-glutathione-ivory-capsule-glutamax-full-review-in-urdu-call0336-6541245/
KS3 Biology 8B Respiration. - ppt video online downloadKS3 Biology 8B Respiration. - ppt video online download
8B Respiration Releasing energy The circulation system Contents 8B Respiration Releasing energy The circulation system The breathing system Anaerobic respiration Summary activities
https://slideplayer.com/slide/4343704/
Low dose systemic heparinization combined with heparin-coated extracorporeal circulation. Effects related to platelets - The...
Methods. One hundred and nineteen -patients -were divid-ed -into 3 -groups: -group A (n=39) -had a stan-dard uncoat-ed extra-cor-po-real cir-cu-la-tion (-ECC)--set -and system-ic hep-ar-in -was giv-en in an -initial -dose of 400 IE/kg -body -weight. During -ECC acti-vat-ed clot-ting -time (-ACT) -was -kept at ≥480 sec. Group B (n=42) -had -the -same -ECC--set com-plete-ly coat-ed -with -low molec-u-lar -weight hep-ar-in, i.v. hep-ar-in -was admin-is-tered in -the -same -dose as in -group A, -ACT -was -again -kept at ≥480 -sec. Group C (n=38) -had -the -same coat-ed -ECC -set -as -group B, -but i.v. hep-ar-in -was -reduced to 150 IE/kg -and dur-ing -ECC -ACT -was maintained of ≥240 -sec ...
https://www.minervamedica.it/en/journals/cardiovascular-surgery/article.php?cod=R37Y2001N05A0579
Nitric Oxide Inhibits Neutrophil Adhesion during Experimental Extracorporeal Circulation | Anesthesiology | ASA PublicationsNitric Oxide Inhibits Neutrophil Adhesion during Experimental Extracorporeal Circulation | Anesthesiology | ASA Publications
Polymorphonuclear leukocytes isolated as described before, were fluorescence labeled with a hydrophobic fluorescence compound (3-3-dioctadecyloxacarbocyanine perchlorate (Fluka; Sigma Aldrich) as described by Lo et al. [15] Cells at a concentration of 1 - 5 x 106cells/ml were incubated with 50 [micro sign]g/ml Fluka in HAP buffer for 10 min at 0 [degree sign]C, unbound dye was removed by three washes with HAP buffer, and labeled PMNs were resuspended in medium 199 for the adhesion assay. Fluka-labeled PMNs (10 [micro sign]l of 106cells/ml) were added to twice-washed EC monolayers. Adhesion was allowed to proceed for 15 min at 37 [degree sign]C, and unbound PMNs were removed by three washes with medium 199. Residual adherent PMNs on EC surfaces were counted manually, in a blinded manner, on an inverted microscope equipped for fluorescence using the filter IF355-550 at a magnification of x100. Values of five replicates from each circuit were averaged, and the coefficients of variation between ...
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=2028098
Extracorporeal Circulation in a Patient with Heparin-induced Thrombocytopenia | Anesthesiology | ASA PublicationsExtracorporeal Circulation in a Patient with Heparin-induced Thrombocytopenia | Anesthesiology | ASA Publications
We have emailed you at with instructions on how to set up a new password. If you do not receive an email in the next 24 hours, or if you misplace your new password, please contact:. ASA members: ...
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1955209
Extracorporeal Circulation Without Bleeding | Science Translational MedicineExtracorporeal Circulation Without Bleeding | Science Translational Medicine
Thank you for your interest in spreading the word about Science Translational Medicine.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://stm.sciencemag.org/content/6/222/222fs7.short?rss=1
Medical and social peculiarities of methodology and analysis of perinatal death causes in women with extracorporal...
The aim of the study was to develop and implement the most accurate methods for evaluating perinatal losses in women with extracorporal fertilization.
http://vestnik.mednet.ru/content/view/543/30/lang,en_US.ISO8859-1/
AmSECT : Blogs : Impact of minimally invasive extracorporeal circuits on octogenarians undergoing coronary artery bypass...AmSECT : Blogs : Impact of minimally invasive extracorporeal circuits on octogenarians undergoing coronary artery bypass...
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership.. Click Here to Learn More ...
http://www.amsect.org/blog/impact-of-minimally-invasive-extracorporeal-circuits-on-octogenarians-undergoing-coronary-artery-bypass-grafting.-have-we-been-looking-in-the-wrong-direction
Dr. Smiths ECG Blog: Weakness and Dyspnea with a Sine Wave. Its not what you think!Dr. Smiths ECG Blog: Weakness and Dyspnea with a Sine Wave. Its not what you think!
Very large doses of IV Bicarb, and 2-4 g IV Magnesium (as a nonspecific therapy for long QT), and IFE only if the patient is in refractory shock and cannot be put on extracorporeal circulation. Transcutaneous or transvenous pacing may be critical as well. Get the patient on extracorporeal life support as quickly as possible in cases that are likely to be refractory to medical therapy ...
http://hqmeded-ecg.blogspot.com/2015/03/weakness-and-dyspnea-with-sine-wave-its.html
Patente US5695717 - Gas exchange apparatus - Google PatentesPatente US5695717 - Gas exchange apparatus - Google Patentes
A gas exchange device (100) with an extracorporeal blood circuit (102) in which a blood pump (110) is connected, with a CO2 exchange unit (112), and an oxygenator (128), whereby the gas exchange unit (112, 128) is in each case divided by a hydrophilic, water-wet membrane (114, 130) into a blood chamber (116, 132) and a gassing chamber (118, 134) which is under positive transmembrane pressure.
http://www.google.es/patents/US5695717?dq=flatulence
Portfolio | Gebert Rüf StiftungPortfolio | Gebert Rüf Stiftung
After years of research at ETH Zurich and University Hospital Zurich, we want to develop and bring a breakthrough blood purification approach based on highly magnetic nanoparticles to the clinics. These tiny non-toxic nanomagnets are chemically equipped with specific binding agents against harmful disease-causing substances. The nanomagnets are administered to an extracorporeal blood circuit which is connected to the patients blood stream. There they selectively bind to the harmful compounds. Before the blood flows back to the patient, the magnets are removed along with the target substances by a highly efficient magnetic separator ...
https://www.grstiftung.ch/de/media/portfolio~grs-024-16~.html
BBM/Aesculap AGBBM/Aesculap AG
Aesculap AG (AAG): B. Braun is one of the worlds leading suppliers of healthcare products. Its four divisions orient their products and services toward different medical fields: hospital, surgery, private practice (medical care and doctors offices) and extracorporeal blood treatment. By networking the divisions knowledge and developing solutions for the healthcare system, the company transforms products and services into integrated systems. B. Brauns Aesculap Division focuses on products and services for all of the core processes in surgery. Aesculap Divisions headquarters are in Tuttlingen, Germany, where it has about 3,100 employees. Internationally, Aesculap has about 9,000 personnel, and production sites all over the world. Its product range includes surgical instruments for open or minimally invasive approaches, implants, surgical sutures, sterile container, storage, motor and navigation systems, as well as products for cardiology. Aesculap is the market leader in CT-free navigation ...
http://lifelongjoints.eu/bbmaesculap-ag/
CRRT | Max HospitalCRRT | Max Hospital
Delivers a complete range of continuous extracorporeal blood therapies with a highly versatile platform that can be customized to specific patient needs, particularly used in renal transplant therapy.. ...
https://www.maxhealthcare.in/technologies/crrt
Flush-mounted circulation valve Aquastrom UP-Therm DN 15, both ports female thread, with protection/operating cap, bronze -...Flush-mounted circulation valve Aquastrom UP-Therm DN 15, both ports female thread, with protection/operating cap, bronze -...
Flush-mounted circulation valve Aquastrom UP-Therm Thermostatic circulation regulating valve for hydronic balancing of potable water circulation systems ...
https://www.oventrop.com/en-GB/productssystems/articledetails/4225104
Flush-mounted circulation valve Aquastrom UP-Therm DN 15, both ports female thread, 57°C, for intermediate ceiling...Flush-mounted circulation valve Aquastrom UP-Therm DN 15, both ports female thread, 57°C, for intermediate ceiling...
Flush-mounted circulation valve Aquastrom UP-Therm Thermostatic circulation regulating valve for hydronic balancing of potable water circulation systems ...
https://www.oventrop.com/en-SE/productssystems/articledetails/4225004
Artificial Circulation and Its Role in Reanimation - Avinpharma.ruArtificial Circulation and Its Role in Reanimation - Avinpharma.ru
From the beginning of the Thirties of the 20th century, right up to the present, many different designs for artificial circulation to be used both in experiments and in clinical practice, in cases of temporary arrest of cardiac circulation, have been described, es-pecially in connection with the use of such apparatus in cardio-vascular surgery. The expedience of using it in resuscitation however, was first suggested by Bryukhonenko and Chechulin. In order to determine the efficacy of artificial circulation in treating clinical death, Bryukhonenko devised his own perfusion apparatus, which he called an autojector.. Research carried out along these lines has confirmed the possibility of restoring respi-ration and cardiac activity by means of extracorporeal circulation in cases of clinical death due to loss of blood, drowning, asphyxia, explosive decom-pression, electric shock, and prolonged hypo-tension. It was found that use of this method to treat clinical death ensured sufficient circu-lation ...
http://avinpharma.ru/en/clinical-pathophysiology/artificial-circulation-and-its-role-in-reanimation.html
AmSECT : Blogs : Optimal blood pressure during cardiopulmonary bypass defined by cerebral autoregulation monitoring.AmSECT : Blogs : Optimal blood pressure during cardiopulmonary bypass defined by cerebral autoregulation monitoring.
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership.. Click Here to Learn More ...
http://www.amsect.org/blog/optimal-blood-pressure-during-cardiopulmonary-bypass-defined-by-cerebral-autoregulation-monitoring.
Vretzakis G. | Authors | e-journal.grVretzakis G. | Authors | e-journal.gr
This study was undertaken to examine the impact of the variations of cardiac mechanical work in hearts respiratory quotient (RQ) and venoarterial carbon dioxide difference (ΔPCO2). In twenty-seven patients undergoing coronary artery bypass grafting under extracorporeal circulation, a coronary sinus line was instituted and its correct position was verified by the waveform displayed in the monitor. Immediately after cannulae placement, a haemodynamic profile was obtained and simultaneous arterial and coronary sinus (a & cs) sampling for blood gas analysis was done in an ABL 720 (Radiometer Copenhagen) analyzer. Continue reading → ...
https://e-journal.gr/authors/vretzakis-g/
S100 protein, an early and prognostic serum marker for brain damage following cardiac surgeryS100 protein, an early and prognostic serum marker for brain damage following cardiac surgery
article{f801030f-b1c8-4f04-9f4e-0159e0e77eab, abstract = {,p,S100 protein is a marker for brain damage easily analysed in blood. The serum level immediatly after termination of extracorporeal circulation (ECC) is increased and associated to age and the duration of perfusion. A prolonged residual concentration indicates cellular brain damage. The objective of this study was to ascertain if the prognosis of individual patients, with stroke following ECC, could be predicted by the S100 levels. 224 patients with an uneventful outcome constituted a reference population. Blood samples for the analysis of S100 were collected at termination of ECC (TO) and at 5, 15 and 48 hours thereafter. Eight patients with stroke following ECC were analysed. In 4, S100 levels continued to increase after ECC. The volume of brain infarctions were large and in 3 of the patients outcome was fatal. In 4 other patients with small volume brain injury S100 dropped initially, but after 5 hours the elimination slowed down, ...
https://lup.lub.lu.se/search/publication/f801030f-b1c8-4f04-9f4e-0159e0e77eab
vein | Definition of vein in English by Oxford Dictionariesvein | Definition of vein in English by Oxford Dictionaries
Definition of vein - any of the tubes forming part of the blood circulation system of the body, carrying in most cases oxygen-depleted blood towards th
https://en.oxforddictionaries.com/definition/vein
Formation of lactic acid in muscles (Simple Explanation)Formation of lactic acid in muscles (Simple Explanation)
Describe the formation of lactic acid in muscles. This concerns two types of muscule cell respiration - aerobic and anaerobic. Anaerobic respiration of the cells in muscle tissue breaks down glucose to form lactic acid. This happens if the persons breathing and blood circulation systems are unable to supply sufficient oxygen to the muscle tissues to enable aerobic respiration to take place. The accumulation of lactic acid creates an oxygen-debt because the body then needs to take in more oxygen to help to remove the lactic acid build-up.
http://www.ivyroses.com/HumanBody/Muscles/lactic-acid-formation.php
Stony Brook University Graduate Bulletin - Spring 2013 - MEC
Building is treated as a time-dependent energy system, with its interactive components coupled through energy and mass flows under an environment defined in terms of sunlight, ambient air and wind and with its equipment which assist in meeting building-dwellers comfort requirements. Major components discussed are thermal mass (both interior mass and envelope mass) and their thermal capacities, building envelopes and their heat transfer resistances, room air including its circulation and heat exchange with thermal mass, and the transparent part of the envelope the glazing or windows and the solar system passing through it during the day and the heat loss during the night time. Major equipment include lighting, air circulation system, cooling and heating equipment, solar thermal panels and solar PV panels, and other equipment including integrated electric and control units. Of the comfort requirements only temperature-and-humidity and illumination are studied with the objective of creating, ...
http://sb.cc.stonybrook.edu/gradbulletin/2013/spring/courses/mec/
Cardiac Biomarkers Market - Alarming Rise in Heart Diseases to Influence Market Growth | Mumbai DailyCardiac Biomarkers Market - Alarming Rise in Heart Diseases to Influence Market Growth | Mumbai Daily
The report demonstrates a far reaching blueprint of the whole headway heading of the market over the navigation of the figure time traverse. Unmistakable zones have been considered to give the perusers a broad perspective of the whole market condition. The commanding scene in thought with the principal affiliations and the affiliations working in the market has been incorporated and examined upon minutely. Unmistakable locales have in addition been cleared up where the market is working feasibly and the areas where the players may discover lucrative open passages later on have in like way been said in the report.. Cardiac biomarkers are the substances used to identify the hazard stratification of a patient with chest torment or suspected intense coronary disorder (ACS). These biomarkers are discharged in blood when the heart is harmed or pushed. The tests that are done by acquainting the cardiac biomarkers with the circulation system help in deciding the dangers of related heart conditions, for ...
http://www.mumbaidaily.in/story/30304/cardiac-biomarkers-market-alarming-rise-in-heart-diseases-to-influence-market-growth.html
Table Top Low Speed Large Capacity Centrifuge | Fountains Healthcare | Medical Devices & EquipmentTable Top Low Speed Large Capacity Centrifuge | Fountains Healthcare | Medical Devices & Equipment
Features: * Programmable microprocessor control(AC brushless motor) *LCD display: speed, RCF，time, conversion of RPM/RCF * External cold-rolled steel with powder coating, stainless steel centrifugal chamber and lid * Fan-forced air circulation system for fast recovery of temperature * 10 procedures of adjustable speed from levels 0 to 9 and 40 kinds of self-defining modes * Electronic lock lid and interlock safety system. Auto lock rotor system * Alarm: lid open, imbalance, over speed and rotor mounting abnormally Functions: RCF selection, quick run, automatic rotor recognition and backup. Electronic imbalance detection, dynamic electric brake system, inching function, short-spin function Model BKC-TL5LII Max. Capacity 4*750ml Max. Speed 5500rpm Max. RCF 5310xg Speed Accuracy ±20rpm Timing Range 0~99h59min59s Noise |58dB Consumption 2.5KW Power Supply AC220V, 50Hz External Size(W*D*H) mm 800*700*400 Package Size(W*D*H) mm 950*850*600 Net Weight(kg) 110 Gross Weight(kg) 135
https://fountainshealth.com/product/table-top-low-speed-large-capacity-centrifuge/
Diastolic high bloodstream pressure (hypertension): Causes, signs and symptoms, and treatment - Latin-Hearts
There are many reasons for diastolic high bloodstream pressure, having a diastolic studying of more than 90mmHg and above considered high. The next are the most typical high diastolic bloodstream pressure causes.. Primary hypertension: This kind describes a condition of high bloodstream pressure that isnt related to a known disease cause, for example stiff or hardened bloodstream vessels. Its thought that primary hypertension manifests as a result of mixture of genes and ecological factors, with lots of common genetic variants being accountable for its development getting been identified. Getting isolated diastolic hypertension is mainly observed in youthful adults and isnt seen to become related to any particular cause, but are closely related to endocrine hormone imbalances or inappropriate contraction of small circulation system wall muscles.. Endocrine and kidney causes: Those hormones consists of an accumulation of glands that secrete hormones into the circulatory system. These hormones ...
http://latin-hearts.com/diastolic-high-bloodstream-pressure-hypertension-causes-signs-and-symptoms-and-treatment/
Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura: Costs for...Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura: Costs for...
Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura (costs for program #34965) ✔ Academic Hospital Nordwest ✔ Department of Oncology and Hematology ✔ BookingHealth.com
https://bookinghealth.com/hospital-nordwest/treatment-programs/34965-extracorporeal-blood-correction-hemosorption-immunoadsorption-plasmapheresis-in-henoch-schonlein-purpura.html
Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura: Costs for...Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura: Costs for...
Extracorporeal blood correction (hemosorption, immunoadsorption, plasmapheresis) in Henoch-Schonlein purpura (costs for program #144113) ✔ Academic Hospital Harlaching ✔ Department of Hematology, Oncology and Palliative Medicine ✔ BookingHealth.com
https://bookinghealth.com/harlaching-clinic/treatment-programs/144113-extracorporeal-blood-correction-hemosorption-immunoadsorption-plasmapheresis-in-henoch-schonlein-purpura.html
Carbon Dioxide Removal after Paris - Ecology Law QuarterlyCarbon Dioxide Removal after Paris - Ecology Law Quarterly
Notwithstanding adoption of the Paris Agreement on climate change, mitigation of greenhouse gas emissions appears unlikely to achieve the stated goal of limiting the mean global temperature increase to 2°C. Under many scenarios, achieving this goal would require not only vigorous mitigation efforts, but also the deployment of carbon dioxide removal technologies or solar geoengineering. While serious consideration of solar geoengineering remains fraught with peril, the use of carbon dioxide removal to remove carbon dioxide from the atmosphere and store it elsewhere appears increasingly likely. Carbon dioxide removal techniques generally would have to be undertaken on a massive scale to be effective. However, the techniques are not ready for deployment, and their widespread use would impact land use, biodiversity, food security, water availability, and other resources.. Such impacts demand greater attention to managing carbon dioxide removal efforts and their effects. The Paris Agreement does not ...
http://www.ecologylawquarterly.org/print/carbon-dioxide-removal-after-paris/
Extracorporeal Membrane Oxygenation in Pregnancy: An Analysis of the Extracorporeal Life Support Organization Registry | Read...Extracorporeal Membrane Oxygenation in Pregnancy: An Analysis of the Extracorporeal Life Support Organization Registry | Read...
OBJECTIVES: We examined data from the International Registry of the Extracorporeal Life Support Organization to identify risk factors for mortality in pregnant and peripartum patients receiving extracorporeal membrane oxygenation.. DESIGN: Retrospective analysis.. SETTING: International Registry of Extracorporeal Life Support Organization.. PATIENTS: We collected de-identified data on all peripartum patients who needed extracorporeal membrane oxygenation between 1997 and 2017 using International Classification of Diseases, 9th and 10th Edition criteria.. INTERVENTIONS: Our primary outcome measure was in-hospital mortality. We also collected data on demographics, preextracorporeal membrane oxygenation ventilator, hemodynamic and biochemical parameters, extracorporeal membrane oxygenation mode, duration, and complications. Initial bivariate analysis assessed potential associations between survival and various preextracorporeal membrane oxygenation as well as extracorporeal membrane ...
https://read.qxmd.com/read/32191415/extracorporeal-membrane-oxygenation-in-pregnancy-an-analysis-of-the-extracorporeal-life-support-organization-registry
Transport of sulfur oxides within the Los Angeles sea breeze/land breeze circulation system - CaltechAUTHORSTransport of sulfur oxides within the Los Angeles sea breeze/land breeze circulation system - CaltechAUTHORS
The sea breeze/land breeze circulation system in the Los Angeles area results in transport of pollutants seaward at night followed by return of aged material inland the next day. This characteristic wind reversal pattern both increases the retention time available for the oxidation of SO_2 to form sulfates and causes individual air parcels to make multiple passes over large coastal emissions sources. As a result, the Los Angeles atmosphere exhibits high peak day and high annual mean sulfate concentrations in spite of the fact that sulfate concentrations in marine background or desert air are low. ...
https://authors.library.caltech.edu/49753/
Options for supporting Carbon Dioxide Removal - C2G
The IPCC says limiting global warming to 1.5°C with no temperature overshoot will require large-scale Carbon Dioxide Removal (CDR). While emission reductions remain the first priority, simultaneously developing CDR options will be necessary to ensure they are available at the scale required to achieve global net-negative CO2 emissions in the second half of the century.. But how might this be achieved in practice?. The NewClimate Institute, with support from C2G, explores some of the options and challenges in the discussion paper Options for supporting Carbon Dioxide Removal.. Key issues include:. ...
https://www.c2g2.net/options-for-supporting-carbon-dioxide-removal/
Patent US5698090 - Artificial kidney for adjusting a concentration of substance in blood - Google PatentsPatent US5698090 - Artificial kidney for adjusting a concentration of substance in blood - Google Patents
An artificial kidney comprises an exchanger (1) having two compartments (2, 3) separated by a semipermeable membrane (4), a first compartment (2) being connected to a circuit (5, 7) for extracorporeal blood circulation, the second compartment (3) having an outlet for draining waste liquid. Means (22, 25) are provided for controlling the flow rate (QA) of a sterile solution containing a substance (A) to be perfused into the circuit (5, 7) for conveying a flow of blood outside the body, which flow rate is controlled as a function of the flow rate (QOUT) of waste liquid. This kidney makes it possible to dose a substance such as a medicine, glucose or bicarbonate, accurately into the blood of a patient undergoing treatment by hemofiltration, hemodialysis, or hemodiafiltration.
http://www.google.com/patents/US5698090?dq=5708422
Brevet US5779365 - Temperature sensor for medical application - Google BrevetsBrevet US5779365 - Temperature sensor for medical application - Google Brevets
A small sized temperature sensor for measuring temperatures in the body and for measuring temperatures in an extracorporeal blood circulation circuit, wherein the possibility of electrical shock and the cost are reduced, while resolution and reliability are increased. The temperature sensor comprises a source of light, an optical fiber to receive light from the light source at one end of the optical fiber, a transducer positioned near the other end of the optical fiber, a reflection means for reflecting the irradiated light, and an arithmetic processing unit which calculates temperature based upon the reflected light measured. The transducer is made up of at least two polymers that have different temperature dependencies of refractive index and form a microphase separation structure, wherein the polymers are cured products made from a cationically polymerizable compound having epoxy groups and a radically polymerizable compound having radically unsaturated groups.
http://www.google.fr/patents/US5779365
US Patent for Cardiopulmonary resuscitation and assisted circulation system Patent (Patent # 4,928,674 issued May 29, 1990) -...US Patent for Cardiopulmonary resuscitation and assisted circulation system Patent (Patent # 4,928,674 issued May 29, 1990) -...
A vest system for generating cyclic fluctuations in intrathoracic pressure for use in cardiopulmonary resuscitation and non-invasive circulatory assistance. The vest is preferably provided with a two bladder inflation system. A high pressure bladder contacts the chest wall while a bias bladder is disposed between the high pressure bladder and the vest material. The bias bladder is pressurized to press the high-pressure bladder tightly against the chest wall so that cyclic inflation of the high-pressure bladder can generate large changes in intrathoracic pressure. The bias bladder is released periodically to allow the chest to expand for adequate ventilation. Air flow into and out of each bladder is controlled by sequencing large bore 3-way and 2-way solenoid valves and the rate of air flow into the high-pressure bladder is controlled by a variable resistor.
https://patents.justia.com/patent/4928674
Heart bypass surgery - PostsHeart bypass surgery - Posts
Heart bypass surgery - MedHelps Heart bypass surgery Center for Information, Symptoms, Resources, Treatments and Tools for Heart bypass surgery. Find Heart bypass surgery information, treatments for Heart bypass surgery and Heart bypass surgery symptoms.
http://www.medhelp.org/tags/show/16318/Heart-bypass-surgery?section=subjects&page=2
10th International Congress of Croatian Society for Extracorporeal Circulation - CROSECT | Belsect | The Belgian Society for...10th International Congress of Croatian Society for Extracorporeal Circulation - CROSECT | Belsect | The Belgian Society for...
BelSECT is the professional organisation for all Belgian perfusionists. Our aims are to develop the profession of perfusion in Belgium, to represent the members of our society towards the authorities and other private and public organisations, national and international.
https://www.belsect.be/events/10th-international-congress-of-croatian-society-for-extracorporeal-circulation-crosect
Carbon Dioxide Removal / Greenhouse Gas Removal - Geoengineering MonitorCarbon Dioxide Removal / Greenhouse Gas Removal - Geoengineering Monitor
Greenhouse Gas Removal (GGR) refers to an technique that removes greenhouse gases from the atmosphere through mechanical means. A more common umbrella term is Carbon Dioxide Removal (CDR), which excludes methods that remove other greenhouse gases such as methane.. ...
https://www.geoengineeringmonitor.org/cat/technologies/carbon-dioxide-demoval/
Evaluation of the Carbon Dioxide Removal Assembly Requirements for the Space Station Freedom in the Manned Tended Capability...Evaluation of the Carbon Dioxide Removal Assembly Requirements for the Space Station Freedom in the Manned Tended Capability...
Analyses have been conducted to assess the capability of the Atmosphere Revitalization Subsystem to control ambient CO2 levels of the Space Station Freedom (SSF). The adequacy of the Carbon Dioxide Removal Assembly (CDRA) performance to meet design requirements has been evaluated. Analyses considered transient effects of crew location and metabolic loading on SSF Restructure configurations. The analyses consisted of computer simulations of on-orbit conditions using both supplier provided and adjusted CO2 removal performance approximations along with derived crew metabolic activities and locations. Results show that while the current performance of the CDRA will maintain CO2 levels within specifications for Man-Tended Operations, it cannot maintain the SSF atmosphere below specifications during Permanently Manned Operations. Potential design options are discussed and other relevant analyses are summarized ...
http://papers.sae.org/921231/
Now is the time for an honest conversation about carbon dioxide removal - Bellona.orgNow is the time for an honest conversation about carbon dioxide removal - Bellona.org
As appearead on Euractiv on 6/10/2020. The European Commissions new climate plan for 2030 increases uncertainties and gives us a rude awakening on carbon removal, writes Mark Preston.. Last month, the European Commission announced it will raise the EU 2030 target to at least -55%, also introducing the idea of a Net target (instead of an absolute one) for 2030 for the first time in the public debate. The Impact Assessment accompanying the Commissions proposal only assessed net targets, revealing that this idea has been in the making for some time, despite this not being explicit in the public consultations. We have now been faced with a rude awakening on the issue of negative emissions, long overlooked by climate policy.. The conversation on Carbon Dioxide Removal (CDR) is severely overdue, but this not only due to the new targets. In late September, the Norwegian government announced a huge plan for geological CO2 storage, a vital part of the chain for many carbon removal processes.The topic ...
https://bellona.org/news/carbon-dioxide-removal/2020-10-now-is-the-time-for-an-honest-conversation-about-carbon-dioxide-removal
Carbon Dioxide Removal and the City | Urban Green CouncilCarbon Dioxide Removal and the City | Urban Green Council
According to the U.N. IPCC (October 2018), carbon dioxide removal (CDR) on a massive scale will be necessary to limit global temperature change to 1.5°C this century. Growing attention to this has focused mainly on a handful of nature-based and industrial solutions that appear to be decidedly un-urban in their footprint, operation and logistical demands.
https://www.urbangreencouncil.org/content/events/carbon-dioxide-removal-and-city
Rickels, W.; et al. (2018): Integrated Assessment of Carbon Dioxide Removal - Climate Engineering - Kiel Earth InstituteRickels, W.; et al. (2018): Integrated Assessment of Carbon Dioxide Removal - Climate Engineering - Kiel Earth Institute
Rickels, W.; Reith, F.; Keller, D.; Oschlies, A.; Quaas, M. F. (2018): Integrated Assessment of Carbon Dioxide Removal. In Earths Future 6 (3), pp. 565-582. DOI: …
https://www.climate-engineering.eu/single/rickels-w-et-al-2018-integrated-assessment-of-carbon-dioxide-removal.html
Options for supporting Carbon Dioxide Removal - NewClimate InstituteOptions for supporting Carbon Dioxide Removal - NewClimate Institute
This paper examines the broad policy frameworks that can support the development and upscaling of Carbon Dioxide Removal and, in particular, whether CDR can be supported by offsetting schemes.
https://newclimate.org/2020/07/28/options-for-supporting-carbon-dioxide-removal-discussion-paper/?shared=email&msg=fail
Carbon Dioxide Removal News on Environmental XPRTCarbon Dioxide Removal News on Environmental XPRT
Get the latest carbon dioxide removal news on Environmental XPRT, the worlds largest environmental industry marketplace and information resource.
https://www.environmental-expert.com/news/keyword-carbon-dioxide-removal-11353
A two-year analysis of therapeutic apheresis practices in a tertiary center: are we chasing the new indications? - hippokratia...A two-year analysis of therapeutic apheresis practices in a tertiary center: are we chasing the new indications? - hippokratia...
Conclusion: Therapeutic apheresis is a progressively developing, safe, and effective treatment modality with add-on indications. Physicians should keep track of new developments on this modality to implement the appropriate indications into clinical practice. HIPPOKRATIA 2018, 22(4): 167-172.. Keywords: therapeutic apheresis, indications, ASFA. Corresponding author: Ersan Sibel, MD, Department of Nephrology of Izmir Tepecik Research and Training Hospital, University of Health Sciences, 35170, Izmir, Turkey, tel: +902324696969, fax: +902324330756, e-mail: [email protected] Introduction. Therapeutic apheresis (TA) is a general term for all extracorporeal blood purification procedures in which components of blood are separated through an extracorporeal device to treat a disease1. Depletion of the offending pathogenic constituent from the blood is attained by discarding the collected constituents (antibodies, toxins, cellular elements, etc.) and replacing it with either patients own plasma or ...
https://www.hippokratia.gr/2019/10/27/a-two-year-analysis-of-therapeutic-apheresis-practices-in-a-tertiary-center-are-we-chasing-the-new-indications/
Development of specific adsorbent... preview & related info | MendeleyDevelopment of specific adsorbent... preview & related info | Mendeley
(2005) Weber et al. Biomacromolecules. To develop adsorbents for the specific removal of tumor necrosis factor-alpha (TNF) in extracorporeal blood purification, cellulose microparticles were functionalized either with a monoclonal anti-...
https://www.mendeley.com/research-papers/development-specific-adsorbents-human-tumor-necrosis-factoralpha-influence-antibody-immobilization-p/
The Therapy <b class=caret...The Therapy <b class=caret...
CytoSorb® therapy is an extracorporeal blood purification therapy designed to reduce excessive levels of inflammatory mediators such as cytokines.
https://www.cytosorb-therapy.com/the-therapy/
The Therapy <b class=caret...The Therapy <b class=caret...
CytoSorb® therapy is an extracorporeal blood purification therapy designed to reduce excessive levels of inflammatory mediators such as cytokines.
https://cytosorb-therapy.com/the-therapy/
Bertrand L. JaberBertrand L. Jaber
Does this patient have intrdialytic hemolysis? Grossly translucent hemolyzed blood in the extracorporeal blood line Symptoms vary depending on causes and severity Causes Mechanical High blood flow rate, single-needle dialysis, small-gauge cannula, kinked blood line, highly negative arterial pressure, offset blood pump Dialysate contamination Chloramine: dyspnea, cyanosis (methemoglobinemia, not improved by oxygen therapy), malaise, headache,…. ...
https://www.clinicalpainadvisor.com/author/bertrand-l-jaber-dsm/
Biology | Free Full-Text | Evaluation of Inflammation Caused by Cardiopulmonary Bypass in a Small Animal ModelBiology | Free Full-Text | Evaluation of Inflammation Caused by Cardiopulmonary Bypass in a Small Animal Model
Extracorporeal circulation (ECC) methods are being increasingly used for mechanical support of respiratory and cardio-circulatory failure. Especially, cardiopulmonary bypass (CPB) during cardiovascular surgery, sustenance of the patient’s life by providing an appropriate blood flow and oxygen supply to principal organs. On the other hand, systemic inflammatory responses in patients undergoing cardiovascular surgery supported by CPB contribute significantly to CPB-associated mortality and morbidity. Our previous research showed that CPB causes a systemic inflammatory response and organ damage in a small animal CPB model. We have been studying the effects of hyperoxia and blood plasma substitute on CPB. In this review, we present a study focusing on the systemic inflammatory response during CPB, along with our findings.
https://www.mdpi.com/2079-7737/9/4/81
Patent US20100280430 - Infusion apparatus - Google PatentsPatent US20100280430 - Infusion apparatus - Google Patents
In an infusion apparatus, an infusion line (4) connects a container (2) of an infusion fluid to an extracorporeal blood circuit (23). A first valve (6) closes the infusion line downstream of an infusion pump (5). An expansion chamber (9), provided with a pressure sensor (10), is arranged between the infusion pump and the first valve. A second valve (8) closes a vent line (7) of the expansion chamber. The processor closes the first valve when the container is emptied. After replacement with a new and full container, the processor restarts the pump and selectively opens the first valve or the second valve according to the increase in pressure measured in the expansion chamber.
http://www.google.com.au/patents/US20100280430
US5354277A - Specialized perfusion protocol for whole-body hyperthermia - Google Patents
A method for extracorporeal blood treatment which utilizes a hemodialysis machine capable of heating the dialysis fluids to 48° C., a hollow-fiber, high efficiency hemodialyzer, and a tubular heat exchanger--in addition to various probes and catheters and heated anterior and posterior blankets for the patient--to effect extracorporeal treatment without adverse effect on blood physiology and without the need for general anesthesia.
https://patents.google.com/patent/US5354277A/en
Patent US8123947 - Priming and air removal systems and methods for dialysis - Google PatentsPatent US8123947 - Priming and air removal systems and methods for dialysis - Google Patents
A renal treatment fluid priming method includes priming an extracorporeal circuit connected to a patient with a physiologically compatible fluid, the extracorporeal circuit including an arterial line, a venous line and blood compartment of a blood filter; and pumping from a renal treatment fluid line in communication with the blood filter (i) pulling blood from the patient through the arterial line to flush the physiologically compatible fluid through the arterial line and the blood filter compartment into the renal treatment fluid line and (ii) pulling blood from the patient through the venous line to flush the physiologically compatible fluid through the venous line and the blood filter compartment into the renal treatment fluid line, such that a greater volume of blood is pulled from the patient via (i) and (ii) than a volume of the extracorporeal circuit.
http://www.google.ca/patents/US8123947
JoVE Author Search: Barili F
Anova, Artery, Cardiopulmonary Bypass, Coronary Artery, Coronary Artery Bypass, Coronary Artery Bypass Grafting, Extracorporeal Circulation, Hemodilution, Hemoglobin, Myocardial Revascularization, Patients, Postoperative Complications, Propensity Score, Risk, Surgery, Time
http://labindex.jove.com/author/Barili-F
Scintigraphic assessment of alterations in cardiopulmonary haemodynamics and renal functional activity in patients with endured...
TY - JOUR. T1 - Scintigraphic assessment of alterations in cardiopulmonary haemodynamics and renal functional activity in patients with endured coronary artery bypass grafting. AU - Vesnina, Zh V.. AU - Krivonogov, N. G.. AU - Vecherskiĭ, Iu Iu. AU - Lishmanov, Iu B.. PY - 2015. Y1 - 2015. N2 - OBJECTIVE: By means of scintigraphic methods to assess alterations in cardiopulmonary haemodynamics and renal functional activity in patients with coronary artery disease (CAD) after endured coronary artery bypass grafting (CABG) performed in conditions of extracorporeal circulation (EC) and on the functioning heart.MATERIAL AND METHODS: We examined a total of 40 patients presenting with CAD (mean age 54.90±1.12 years) after endured CABG. All patients were subdivided into 2 groups: Group One consisting of 20 patients subjected to CABG performed on the beating heart with the use of myocardial stabilizer Acrobat (Study Group) and Group Two also comprising 20 patients but undergoing surgery with the ...
https://tpu.pure.elsevier.com/en/publications/scintigraphic-assessment-of-alterations-in-cardiopulmonary-haemod
Gas bubbles are taken under controlGas bubbles are taken under control
A patient on the operating table is exposed to numerous risks, especially if the operation is so complex, that extracorporeal circulation is required. One of the dangers is a risk of embolism by a gas bubble, which may occur in the process of blood circulation in the pump oxygenator. It is not always clear why the gas bubbles originate, but they do almost in all the cases. The smaller ones, less than 10 microns in diameter are not particularly dangerous, as they quite rapidly dissolve by themselves. As for bigger bubbles, they may plug in a vessel like a cork, thus disrupting normal blood circulation and causing very bad problems for the organism ...
http://www.innovations-report.com/html/reports/medicine-health/report-23389.html
κ‑opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the...κ‑opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the...
POCD is a common complication following cardiac surgery and may lead to an extended stay in an intensive care unit or hospital, increased perioperative complications and mortality and a decrease in the ability of the patient to lead an independent life (2). At 1 week following cardiac surgery, the incidence of POCD is as high as 50-70 and ~40% of patients still have cognitive dysfunction at five years following surgery (37,38). CPB surgery can reduce postoperative neurocognitive ability because of hypoperfusion or low mean arterial pressure, hemodynamic instability, cerebral thrombosis, systemic inflammatory responses, anemia, hyperglycemia and extracorporeal circulation trauma (39). In the present study, a CPB rat model was successfully established and treated with a KOR agonist and then the cognitive function, inflammatory response, oxidative stress injury and apoptosis were observed. The results demonstrated that a KOR agonist could improve cognitive function and reduce brain damage in CPB ...
https://www.spandidos-publications.com/10.3892/mmr.2021.11933
Soviet Scientists bring dogs back to life!, page 2Soviet Scientists bring dogs back to life!, page 2
Technically what these scientists did is indeed very possible, its done today, with a few changes and on a live person. They just did it using a Artificial Circulation system, which are still used today in most open heart surgeries. But there are some key factors that must be met for the organs to be revived. Plus, for the time this video was made, it would have been a major medical advancement. Although the experiment seems real and not a fake, certain conditions were met for the revival to be possible, the most important being that the dogs were either perseverated, or died less than 1 hour ago. The head revival part is the most questionable part of the film, but keeping in mind that the brain must have suffered serious oxygen depravation that led to brain cell death and that the brainstem reflexes remained intact (Instincts), the dogs reaction was possible, although he probably wouldnt be able to walk or recognize things, that is, if he still had a body. So, my opinion is that some of the ...
http://www.abovetopsecret.com/forum/thread213214/pg2
Spectrum Medical | clinical EMR systems and Advanced Perfusion TechnologiesSpectrum Medical | clinical EMR systems and Advanced Perfusion Technologies
The American Society of ExtraCorporeal Technology was founded in 1964 with the belief that members of the then-new allied health field could best serve their profession by sharing their thoughts and experiences. Steady growth was the keynote of AmSECT, as the ranks of Perfusionists expanded with the increasing demand for open-heart surgery. During the past decade, changes in lifestyle and improvements in the treatment of cardiac disease have resulted in Perfusionists facing the challenge of identifying new opportunities and expanded their practices in the areas of perioperative blood management, wound healing, ventricular assistance, and expanded uses of extracorporeal circulation.. Today AmSECT has over 2,000 members throughout the world and is dedicated to promoting the profession. The goals of the Society are diverse and include:. ...
https://www.spectrummedical.com/events/amsect.aspx
Introduction - HSE.ieIntroduction - HSE.ie
Cancer begins with an alteration to the structure of the deoxyribonucleic acid (DNA) that is found in all human cells. This is known as a genetic mutation. The DNA provides the cells with a basic set of instructions, such as when to grow and reproduce.. The mutation in the DNA changes these instructions so that the cells carry on growing. This causes the cells to reproduce in an uncontrollable manner, producing a lump of tissue that is known as a tumour.. Most cancers grow and spread to other parts of the body through the lymphatic system. The lymphatic system is a series of glands (or nodes) that are spread throughout your body in a similar way to your blood circulation system. The lymph glands produce many of the specialised cells that are needed by your immune system.. Kidney cancer usually spreads into blood vessels that are located near to the kidney or the adrenal gland. The adrenal gland is an organ that releases adrenaline, which is a naturally produced hormone that the body uses during ...
https://www.hse.ie/eng/health/az/c/cancer,-kidney/
Use of enoximone in the postoperative course of heart surgery]. - Semantic ScholarUse of enoximone in the postoperative course of heart surgery]. - Semantic Scholar
The aim of this study was to evaluate the efficacy and safety of enoximone, an imidazolonic compound inhibiting cardiac phosphodiesterase III, during the postoperative period. The drug was administered prior to the usual stages of weaning the patient off extracorporeal circulation, to a group of 20 subjects who presented an ejection fraction of less than 35% following hemodynamic studies. Patients were randomly subdivided into 4 groups each of which received a different dose of enoximone according to the following protocol: Group A, 1 mg/kg bolus and slow infusion at 10 gamma/kg/min; Group B, 0.5 mg/kg bolus and slow infusion at 15 gamma/kg/min; Group C, 0.5 mg/kg bolus and slow infusion at 10 gamma/kg/min; Group D, slow infusion at 10 gamma/kg/min. The best results in hemodynamic terms and with regard to the positive inotropic and vasodilatory action of the drug in question were obtained in Group C. Increased cardiac output was observed in all patients within 120 minutes of enoximone administration and
https://www.semanticscholar.org/paper/Use-of-enoximone-in-the-postoperative-course-of-h-Ferrara-Golino/cfb064148c6791617f271940fe582518c0c343a0
Remedy for Systemic Inflammatory Response Syndrome (SIRS)Remedy for Systemic Inflammatory Response Syndrome (SIRS)
Injury results in release of cytoplasmic ATP, which is sensed by monocytes/macrophages via ATP receptor P2X7. This swiftly induces inflammasome activation, caspase-1-dependent cleavage and release of interleukin-1ß (IL-1ß), IL-18 and HMGB1. Excessive systemic IL-1ß release is the first stage of a reaction chain causing SIRS and high patient mortality. IL-1ß is involved in host defense against infections. Pathogen-induced inflammasome activation, however, typically involve ATP-independent pathways. Hence, a-1-antitrypsin, SLPI, CRP, and DPPC inhibit injury induced inflammation but do not inhibit clearance of pathogens. Scope of application: SIRS, Major surgery, Trauma, Extracorporeal circulation (e.g. cardiopulmonary bypass, ECMO), Chronic inflammation, Lung injury SIRS-related multi organ dysfunction (MODS) and acute lung injury (ALI) are among the leading causes of death worldwide. The proposed remedies have the potential to become affordable life-saving medicaments for numerous ...
http://www.innovations-report.com/html/reports/technology-offerings/remedy-for-systemic-inflammatory-response-syndrome-sirs.html
Reduction in Requirements for Allogeneic Blood Products: Pharmacologic Methods - Janssens MarcReduction in Requirements for Allogeneic Blood Products: Pharmacologic Methods - Janssens Marc
en] BACKGROUND: Numerous articles describe the reduction of perioperative bleeding by the therapeutic or prophylactic administration of drugs such as prostacyclin, desmopressin, and natural or synthetic antifibrinolytics. METHODS: A review of the literature was carried out to help the reader define the indications of these drugs during cardiopulmonary bypass operations, highlight the questions that remain concerning their indications and modes of action, and suggest future studies to answer these remaining questions. RESULTS: Prostacyclin reduces platelet trauma induced by extracorporeal circulation but does not effectively reduce postoperative bleeding and transfusion requirements. Desmopressin acts as a glue, improving platelet adhesion, and may be effective when postoperative bleeding is excessive, but its routine use in cardiac operations cannot be recommended. Natural and synthetic antifibrinolytics inhibit plasmin and plasmin-induced platelet dysfunction. These agents have been shown to ...
http://orbi.ulg.ac.be/handle/2268/94442
Township of West Whiteland, PA Common RegulationsTownship of West Whiteland, PA Common Regulations
Analysis of traffic impact. The traffic engineer shall evaluate the likely impact of the proposed development in the areas circulation system. Included shall be an evaluation of the proposals likely impact on existing and planned public transportation improvements, the expected impact on pedestrian and nonvehicular circulation, an evaluation of the capacity of existing roadways within the study area to accommodate site-generated traffic, as well as total future traffic demand. (Total future traffic demand shall be defined to include existing vehicular volumes plus traffic volumes associated with approved developments within the study area.) This demand shall consist of a combination of the existing traffic expanded to the completion year (using an annual traffic rate available from Delaware Valley Regional Planning Commission), the development-generated traffic, and the traffic generated by other proposed developments affecting the study area. The traffic engineer shall render an opinion ...
https://ecode360.com/11703176
Township of West Whiteland, PA Common RegulationsTownship of West Whiteland, PA Common Regulations
Analysis of traffic impact. The traffic engineer shall evaluate the likely impact of the proposed development in the areas circulation system. Included shall be an evaluation of the proposals likely impact on existing and planned public transportation improvements, the expected impact on pedestrian and nonvehicular circulation, an evaluation of the capacity of existing roadways within the study area to accommodate site-generated traffic, as well as total future traffic demand. (Total future traffic demand shall be defined to include existing vehicular volumes plus traffic volumes associated with approved developments within the study area.) This demand shall consist of a combination of the existing traffic expanded to the completion year (using an annual traffic rate available from Delaware Valley Regional Planning Commission), the development-generated traffic, and the traffic generated by other proposed developments affecting the study area. The traffic engineer shall render an opinion ...
https://ecode360.com/11703254
SHANGHAI CHINASHANGHAI CHINA
3. to take charge of the administration and guiding of the municipal grain circulation; to study and put forward the scheme of deepening the reform of the grain circulation system and coordinate with relevant authorities to implement; to promote the reform of state-owned grain enterprises; to do a good job in coordination, supervision, inspection and guidance for the reform of state-owned grain procurement and sale enterprises;. 4. to guide, supervise, inspect and serve for the participants in the municipal grain market; to study and put forward the planning of establishing the grain market, coordinate with relevant authorities to manage the grain market and perfect the monitoring and alert system for the grain market; to implement the emergency mechanism for the grain market and put forward suggestions on launching the grain emergency scheme; to take charge of the management of the grain supply to troops and disadvantaged groups as well as the delivery subsidies of the non-staple foodstuff ...
http://www.shanghai.gov.cn/shanghai/node27118/node27386/node27400/node27840/userobject22ai38989.html
Study of High Efficiency Zero-Emission Argon Circulated Hydrogen Engine - SAE InternationalStudy of High Efficiency Zero-Emission Argon Circulated Hydrogen Engine - SAE International
The potential of high efficiency zero-emission engines fueled by hydrogen, which is regarded as a promising form of energy for the future, is being researched. The argon circulated hydrogen engine [ 1 ] is one system theoretically capable of achieving both high efficiency and zero emissions, and its feasibility for use in vehicles has been studied. Specifically, tests were performed to verify the following issues. It was examined whether stable hydrogen combustion could be achieved under an atmosphere of argon and oxygen, which has a high specific heat ratio, and whether the substantial thermal efficiency improvement effect of the argon working gas could be achieved. An argon circulation system was also studied whereby steam, which is the combustion product of the hydrogen and oxygen emitted from the engine, is separated by condensation to enable the remaining argon to be re-used. In addition, the study also examined whether gas impurities accumulated in the circulation gas during continuous ...
http://papers.sae.org/2010-01-0581/
Minimized extracorporeal circulationMinimized extracorporeal circulation
... (MECC) is a kind of cardiopulmonary bypass (heart-lung machine), a part of heart surgery. ... The introduction of extracorporeal circulation has facilitated open heart surgery. The development of modern techniques in ... The benefits of this type of extracorporeal circulation are that a lower consumption of blood and blood products is observed in ... In 1937 Gibbon reports the first successful use of extracorporeal circulation in animals (in this case, cats). On May 6, 1953 ...
https://en.wikipedia.org/wiki/Minimized_extracorporeal_circulation
ExtracorporealExtracorporeal
PMID 12732590 Look up extracorporeal in Wiktionary, the free dictionary. Extracorporeal Circulation. MedicalGlossary.org (CS1 ... An extracorporeal is a medical procedure which is performed outside the body. Extracorporeal devices are the artificial organs ... Extracorporeal shockwave lithotripsy (ESWL), which is unrelated to other extracorporeal therapies, in that the device used to ... Apheresis Autotransfusion Hemodialysis Hemofiltration Plasmapheresis Extracorporeal carbon dioxide removal Extracorporeal ...
https://en.wikipedia.org/wiki/Extracorporeal
Cox maze procedureCox maze procedure
... extracorporeal circulation). After the introduction of the initial procedure, a series of improvements were made, culminating ...
https://en.wikipedia.org/wiki/Cox_maze_procedure
Minimaze procedureMinimaze procedure
... extracorporeal circulation). A series of improvements were made, culminating in 1992 in the Cox maze III procedure, which is ... Circulation. 109 (3): 327-34. doi:10.1161/01.CIR.0000112641.16340.C7. PMID 14707026. Scherlag B, Nakagawa H, Jackman W, ...
https://en.wikipedia.org/wiki/Minimaze_procedure
OxygenatorOxygenator
It has been shown to inhibit intrinsic coagulation, inhibit host responses to extracorporeal circulation, and lessen ... "Studies in Extracorporeal Circulation. I. Applicability of Gibbon-Type Pump-Oxygenator to Human Intracardiac Surgery: 40 Cases ... However, oxygenators can also be utilized in extracorporeal membrane oxygenation in neonatal intensive care units by nurses. ... The researchers concluded that Heparin-coated extracorporeal circuits with reduced systemic heparinization lead to ...
https://en.wikipedia.org/wiki/Oxygenator
Cardiopulmonary bypassCardiopulmonary bypass
CPB is a form of extracorporeal circulation. Extracorporeal membrane oxygenation is generally used for longer-term treatment. ... "Extracorporeal Circulation: Perfusion Systems". In Cohn LH, Edmunds LH (eds.). Cardiac Surgery in the Adult. New York: McGraw- ... For longer periods than this, an ECMO (extracorporeal membrane oxygenation) is used, which can be in operation for up to 31 ... This rewarming method of using CPB is successful if the core temperature of the patient is above 16 °C. Extracorporeal membrane ...
https://en.wikipedia.org/wiki/Cardiopulmonary_bypass
PlacentaPlacenta
Assad RS, Lee FY, Hanley FL (2001). "Placental compliance during fetal extracorporeal circulation". Journal of Applied ... The fetoplacental circulation is vulnerable to persistent hypoxia or intermittent hypoxia and reoxygenation, which can lead to ... ISBN 978-1-259-64433-7.[page needed] Placental blood circulation Archived 2011-09-28 at the Wayback Machine Kiserud T, Acharya ... as foreign fetal cells also persist in the maternal circulation, on the other side of the placental barrier. The placenta also ...
https://en.wikipedia.org/wiki/Placenta
Marian IonescuMarian Ionescu
Ionescu M.I., Wooler G.H. Current Techniques in Extracorporeal Circulation. Butterworths, (!976), London. Ionescu M.I. Tissue ... Ionescu M.I. Techniques in Extracorporeal Circulation. Butterworths,(1981), London. Ionescu M.I., Cohn L.H. Mitral Valve ... with the aid of extracorporeal circulation, in animals and in man. The body temperature was lowered to between 6 and 15 °C and ... Circulation, 111, 2717-2719 , [5] Bodnar E, Yacoub M, Eds. "Biologic and Bioprosthetic Valves" Proceedings of the Third ...
https://en.wikipedia.org/wiki/Marian_Ionescu
John W. KirklinJohn W. Kirklin
Melrose, D. G. (1961). "Types Of Heart-Lung Machines Used In Extra-Corporeal Circulation". Postgraduate Medical Journal. 37 ( ... In 1954, Kirklin's rival, C. Walton Lillehei used the technique of cross circulation to operate on an 11-month-old baby who ... Usually using the parent for cross circulation, he performed 45 operations of ventricular septal defects (VSDs), ASDs and ... Cooley Denton A. (22 June 2004). "John W. Kirklin, MD". Circulation. 109 (24): 2928-2929. doi:10.1161/01.CIR.0000133601.16718. ...
https://en.wikipedia.org/wiki/John_W._Kirklin
Retrograde autologous primingRetrograde autologous priming
It is also can be considered a kind of extracorporeal circulation. There are two primary methods, homologous blood transfusion ... Direct transfusion is a blood salvaging method associated with cardiopulmonary bypass (CPB) circuits or other extracorporeal ... is drained into a re-circulation bag. Before the beginning of the CPB, the crystalloid priming fluid is displaced by the ... blood circulatory and transporting oxygen to red blood cells before blood is flowing backwards the arterial circulation. ...
https://en.wikipedia.org/wiki/Retrograde_autologous_priming
Pokeweed mitogenPokeweed mitogen
... immunotherapy by extracorporeal circulation". Cancer Immunology, Immunotherapy. 32 (2): 125-130. doi:10.1007/BF01754209. PMID ...
https://en.wikipedia.org/wiki/Pokeweed_mitogen
Gerald BuckbergGerald Buckberg
Gibbon Award for Outstanding Contribution to Science and Practice of Extracorporeal Circulation (2008) • Longmire Legacy Award ...
https://en.wikipedia.org/wiki/Gerald_Buckberg
Bubble sensorBubble sensor
P. Kay and C. M. Munsch, Techniques in Extracorporeal Circulation, CRC Press, 2004. (Orphaned articles from October 2015, All ... Table 1 Characteristics of Capacitive Sensors In various medical treatments that use Extracorporeal Blood Circuits (ECBC) the ...
https://en.wikipedia.org/wiki/Bubble_sensor
Pulmonary thromboendarterectomyPulmonary thromboendarterectomy
In patients who are non responsive to this management extra corporeal circulation may be indicated. Each of these strategies ... 1989). "[Surgical treatment of chronic pulmonary embolism using thromboembolectomy under extracorporeal circulation and deep ... In order to achieve this CPB is periodically stopped, resulting in a complete cessation of blood circulation. This is only ... After each interval of arrest circulation is continued for 10 minutes or until pulmonary venous oxygen saturation is at least ...
https://en.wikipedia.org/wiki/Pulmonary_thromboendarterectomy
BioceramicBioceramic
... s are meant to be used in extracorporeal circulation systems (dialysis for example) or engineered bioreactors; ...
https://en.wikipedia.org/wiki/Bioceramic
F. John LewisF. John Lewis
"The first open-heart repairs using extracorporeal circulation by cross-circulation: a 53-year follow-up". Annals of Thoracic ...
https://en.wikipedia.org/wiki/F._John_Lewis
Nikolai AmosovNikolai Amosov
Each year, the institute fulfilled about 3000 heart operations, including over 1500 - with extra-corporeal blood circulation. ... including about 36,000 operations with extra-corporeal blood circulation. In 1983 Amosov's cardiac surgery clinic was ... one was one of the first in the Soviet Union to introduce into the practice the method of artificial blood circulation (in 1963 ...
https://en.wikipedia.org/wiki/Nikolai_Amosov
Kumudben JoshiKumudben Joshi
Development of technics employed in extracorporeal circulation in the years 1961-1976 in the light of 1,200 cases]". ...
https://en.wikipedia.org/wiki/Kumudben_Joshi
PerfusionistPerfusionist
Their role is to conduct extracorporeal circulation as well as ensure the management of physiologic functions by monitoring the ... extracorporeal membrane oxygenation (ECMO) Adult surgical procedures may include: coronary artery bypass, aortic valve ... monitoring circulation, monitoring blood gases, surveil anticoagulation, induction of hypothermia, and hemodilution. Sometimes ...
https://en.wikipedia.org/wiki/Perfusionist
Membrane oxygenatorMembrane oxygenator
Bubble oxygenator Extracorporeal circulation E. Converse Peirce, made refinements to membrane oxygenator Experiments in the ... In the 1920s and 30s, research into developing extracorporeal oxygenation continued. Working independently, Brukhonenko in the ... termed extracorporeal membrane oxygenation (ECMO). A membrane oxygenator consists of a thin gas-permeable membrane separating ... USSR and John Heysham Gibbon in the US demonstrated the feasibility of extracorporeal oxygenation. Brukhonenko used excised dog ...
https://en.wikipedia.org/wiki/Membrane_oxygenator
Pietro ValdoniPietro Valdoni
... then hypothermia and extracorporeal circulation. In order to see Valdoni's operations, surgeons from all over the world came to ...
https://en.wikipedia.org/wiki/Pietro_Valdoni
Giuseppe Di BenedettoGiuseppe Di Benedetto
... without the use of machines for extracorporeal circulation) that allows a percentage of revascularization over 90%; the ... Circulation 119, 2702-2707, 2009 A. Panza, R. Leone, A. Longobardi, P. Masiello, A. Alfano, G. Mastrogiovanni, F. Cafarelli, S ... thoracic aorta in a patient of 60 years with an fissured aneurysm without the aid of the machine for extracorporeal circulation ...
https://en.wikipedia.org/wiki/Giuseppe_Di_Benedetto
Protamine sulfateProtamine sulfate
... when extracorporeal circulation and anticoagulation are no longer needed. It is also used in gene transfer, protein ...
https://en.wikipedia.org/wiki/Protamine_sulfate
Leon Manteuffel-SzoegeLeon Manteuffel-Szoege
1961;33:1040-3 (pl), PMID 14480650 Experience with heart surgery with the use of extracorporeal circulation, Sitkowski W. Jr, ... 1961 Feb 27;16:321-5 (pl), PMID 13766327 Clinical use of Crafoord-Senning's apparatus for extra-corporeal circulation, Nowicki ... 1973;16(5):391-8 (pl), PMID 4764019 Some hemodynamic problems of extracorporeal circulation perfusion in relation to the ... PMID 5330459 An attempt to analyze hemodynamic changes during the use of extracorporeal circulation, Michałowski J., Manteuffel ...
https://en.wikipedia.org/wiki/Leon_Manteuffel-Szoege
Cardiac outputCardiac output
UD requires the establishment of an extracorporeal circulation through its unique AV loop with two pre-existing arterial and ... It is a useful measurement in fetal circulation, where cardiac outputs from both sides of the heart work partly in parallel by ... These instruments average measurements over 2-9 minutes depending on the stability of the circulation, and thus do not provide ... Ultrasound dilution (UD) uses body-temperature normal saline (NS) as an indicator introduced into an extracorporeal loop to ...
https://en.wikipedia.org/wiki/Cardiac_output
Polymyxin BPolymyxin B
The obstacle of the toxicity of polymyxin B is bypassed by extracorporeal circulation with perfusion of venous blood through a ... Shoji H. (February 2003). "Extracorporeal endotoxin removal for the treatment of sepsis: endotoxin adsorption cartridge ( ...
https://en.wikipedia.org/wiki/Polymyxin_B
Hepatorenal syndromeHepatorenal syndrome
Liver dialysis involves extracorporeal dialysis to remove toxins from the circulation, usually through the addition of a second ... Type 2 HRS is thought to be part of a spectrum of illness associated with increased pressures in the portal vein circulation, ... The predominant theory (termed the underfill theory) is that blood vessels in the kidney circulation are constricted because of ... Deteriorating liver function is believed to cause changes in the circulation that supplies the intestines, altering blood flow ...
https://en.wikipedia.org/wiki/Hepatorenal_syndrome
Oxygen saturation (medicine)Oxygen saturation (medicine)
This measurement is often used under treatment with a heart lung machine (extracorporeal circulation), and can give the ...
https://en.wikipedia.org/wiki/Oxygen_saturation_(medicine)
Fat embolism syndromeFat embolism syndrome
Bone marrow transplantation Liposuction Parenteral lipid infusion Decompression sickness Extracorporeal circulation Acute ... the fat globules often get lodged in the pulmonary circulation. Fat globules may also pass through lung circulation back into ... They may also reach the systemic circulation through a patent foramen ovale (a hole communicating the right atrium directly to ... Fat embolism is presence of fat particles in the micro-circulation of the body. Meanwhile, fat embolism syndrome is the ...
https://en.wikipedia.org/wiki/Fat_embolism_syndrome
César Julien Jean LegalloisCésar Julien Jean Legallois
The idea of an extracorporeal circulation was introduced by him in his 1812 monograph Expériences sur le principe de la vie, ...
https://en.wikipedia.org/wiki/César_Julien_Jean_Legallois
Liver support systemLiver support system
The Extracorporeal Liver Assist Device (ELAD) is a human-cell based treatment system. A catheter removes blood from the patient ... However, after 3 hours of plasma circulation, hepatocyte function deteriorated rapidly. This was likely due to the toxic effect ... Manz, T; Ochs, A; Bisse, E; Strey, C; Grotz, W (2003). "Liver support--a task for nephrologists? Extracorporeal treatment of a ... Parés, A; Cisneros, L; Salmerón, JM; Caballería, L; Mas, A; Torras, A; Rodés, J (Jun 2004). "Extracorporeal albumin dialysis: a ...
https://en.wikipedia.org/wiki/Liver_support_system
MetforminMetformin
August 2015). "Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal ... Towler MC, Hardie DG (February 2007). "AMP-activated protein kinase in metabolic control and insulin signaling". Circulation ... Extracorporeal treatments are recommended in severe overdoses. Due to metformin's low molecular weight and lack of plasma ...
https://en.wikipedia.org/wiki/Metformin
Erythropoietic protoporphyriaErythropoietic protoporphyria
Some protoporphyrin in bile is returned to the liver as a consequence of the enterohepatic circulation; the remaining ... Bone marrow transplantation, liver transplantation, acetylcysteine, extracorporeal albumin dialysis, parenteral iron and ... interrupting the enterohepatic circulation. It is usually used in combination with other treatment approaches. Activated carbon ...
https://en.wikipedia.org/wiki/Erythropoietic_protoporphyria
ApheresisApheresis
It is thus an extracorporeal therapy. One of the uses of apheresis is for collecting stem cells. Depending on the substance ... is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation. ... It does require a larger extracorporeal volume, and takes significantly longer to perform the procedure via IFC. As such, it is ... The main advantage of this system is the low extracorporeal volume (calculated by volume of the apheresis chamber, the donor's ...
https://en.wikipedia.org/wiki/Apheresis
ImpellaImpella
... may provide some of the results similar to venoarterial extracorporeal life support and TandemHeart. In patients with ... Circulation. 141 (4): 273-284. doi:10.1161/CIRCULATIONAHA.119.044007. PMID 31735078. S2CID 208143531. (Wikipedia articles with ... "Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis". Intensive Care ... Circulation. 141 (4): 273-284. doi:10.1161/CIRCULATIONAHA.119.044007. PMID 31735078. S2CID 208143531. Ouweneel, DM; Schotborgh ...
https://en.wikipedia.org/wiki/Impella
COVID-19 pandemicCOVID-19 pandemic
Extracorporeal membrane oxygenation (ECMO) has been used to address the issue of respiratory failure. Existing drugs such as ... the origin of COVID-19 requires to change the paradigm on zoonotic emergence from the spillover to the circulation model". ...
https://en.wikipedia.org/wiki/COVID-19_pandemic
Artificial heartArtificial heart
A centrifugal artificial heart which alternately pumps the pulmonary circulation and the systemic circulation, causing a pulse ... It is also distinct from a ventilator, used to support failing lungs, or the extracorporeal membrane oxygenation (ECMO), which ... Prolonged Assisted circulation after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of ... In 2012, a study published in the New England Journal of Medicine compared the Berlin Heart to extracorporeal membrane ...
https://en.wikipedia.org/wiki/Artificial_heart
PlasmapheresisPlasmapheresis
... and return or exchange of blood plasma or components thereof from and to the blood circulation. It is thus an extracorporeal ... where the rapid removal of disease-causing autoantibodies from the circulation is required in addition to other medical therapy ...
https://en.wikipedia.org/wiki/Plasmapheresis
Sorin GroupSorin Group
... an Italian company that was the European leader in the market for extracorporeal blood circulation and autologous blood ...
https://en.wikipedia.org/wiki/Sorin_Group
PupilometerPupilometer
Miroz, John-Paul (February 2020). "Neurological Pupil index for Early Prognostication After Venoarterial Extracorporeal ... Circulation. 142 (16_suppl_2): S366-S468. doi:10.1161/CIR.0000000000000916. ISSN 0009-7322. PMID 33081529. Al-Obaidi, Sameer ( ... Epinephrine and Atropine Given During Advanced Cardiac Life Support in Patients Who Achieve Return of Spontaneous Circulation ...
https://en.wikipedia.org/wiki/Pupilometer
Borys TodurovBorys Todurov
From 2000 to 2003, he was the Head of the Department of Transplantation and Heart Surgery with a group of extra corporeal ... he made a thrombectomy from the inferior vena cava in a complex with nephrectomy under the conditions of artificial circulation ... Roentgen-Endovascular and Extracorporeal Technologies of Shupyk National Medical Academy of Postgraduate Education. In December ...
https://en.wikipedia.org/wiki/Borys_Todurov
Neurological pupil indexNeurological pupil index
Miroz, John-Paul (February 2020). "Neurological Pupil index for Early Prognostication After Venoarterial Extracorporeal ... Circulation. 142 (16_suppl_2): S366-S468. doi:10.1161/CIR.0000000000000916. ISSN 0009-7322. PMID 33081529. Mazhar, Khadijah ( ...
https://en.wikipedia.org/wiki/Neurological_pupil_index
ErythrocytapheresisErythrocytapheresis
It is an extracorporeal blood separation method whereby whole blood is extracted from a donor or patient, the red blood cells ... are separated, and the remaining blood is returned to circulation. For the separation of erythrocytes, whole blood is passed ...
https://en.wikipedia.org/wiki/Erythrocytapheresis
Liquid ventilatorLiquid ventilator
This procedure can be performed with either a membrane oxygenator (a technology used in extracorporeal oxygenators) or a bubble ... Circulation. 124 (8): 9011-11. doi:10.1161/circulationaha.111.039388. PMC 3375236. PMID 21810660. (in English and French) ... increased risk of intracranial hemorrhage and for whom their small vessel size poses technical limitations for Extracorporeal ...
https://en.wikipedia.org/wiki/Liquid_ventilator
Extracorporeal membrane oxygenationExtracorporeal membrane oxygenation
... which provides shorter-term support with arrested native circulation. The device used is a membrane oxygenator, also known as ... Extracorporeal membrane oxygenation (ECMO), also known as extracorporeal life support (ECLS), is an extracorporeal technique of ... Guidelines that describe the indications and practice of ECMO are published by the Extracorporeal Life Support Organization ( ... allowing treatment of the underlying cause of arrest while circulation and oxygenation are supported. ECMO is also used to ...
https://en.wikipedia.org/wiki/Extracorporeal_membrane_oxygenation
ThoratecThoratec
It is cleared for clinical use up to six hours, and can be used as a short-term solution to support the circulation while ... American Society of ExtraCorporeal Technology. "VE LVAS for End-Stage Heart Failure". Perfusion.com. September 1, 2004. "FDA ... It is cleared for clinical use up to six hours, and can be used as a short-term solution to support the circulation while ... It is surgically implanted just below the diaphragm in the abdomen and attached to the aorta, leaving natural circulation in ...
https://en.wikipedia.org/wiki/Thoratec
Cardiothoracic anesthesiologyCardiothoracic anesthesiology
The surgeon places a cannula in the right atrium, vena cava, or femoral vein to withdraw blood from the venous circulation. The ... medical or surgical critical care and extracorporeal perfusion technology.[citation needed] Fellows are offered the opportunity ... Blood is drained from the venous (deoxygenated) circulation, and is cycled through the CPB machine. While in the machine, the ... Subsequently, it is pumped back into the arterial (oxygenated) circulation, thereby bypassing the heart and lungs and ...
https://en.wikipedia.org/wiki/Cardiothoracic_anesthesiology
EXTRACORPOREAL CIRCULATION AND PLATELETS | Anesthesiology | American Society of AnesthesiologistsEXTRACORPOREAL CIRCULATION AND PLATELETS | Anesthesiology | American Society of Anesthesiologists
Nitric Oxide Inhibits Neutrophil Adhesion during Experimental Extracorporeal Circulation Anesthesiology (August 1998) ... EXTRACORPOREAL CIRCULATION AND PLATELETS. Anesthesiology 1976; 44:367 doi: https://doi.org/10.1097/00000542-197604000-00029 ... Management of Extracorporeal Membrane Oxygenation for Postcardiotomy Cardiogenic Shock Anesthesiology (September 2021) ... Perioperative Management of the Adult Patient on Venovenous Extracorporeal Membrane Oxygenation Requiring Noncardiac Surgery ...
https://pubs.asahq.org/anesthesiology/article/44/4/367/24676/EXTRACORPOREAL-CIRCULATION-AND-PLATELETS
IMSEAR at SEARO: Extracorporeal circulation.
Basu AK, Gupta S, Haq A, Islam N, Banerjee C. Extracorporeal circulation. Journal of the Indian Medical Association. 1965 Aug; ...
https://imsear.searo.who.int/handle/123456789/101518
Coronary artery bypass grafting without extracorporeal circulationCoronary artery bypass grafting without extracorporeal circulation
... is leader not only in Italy but also in Europe in Coronary artery bypass grafting without extracorporeal circulation with at ... Avoiding extracorporeal circulation is a good solution resulting in some clinical advantages: * It prevents adverse ... Diagnosis and treatment of Coronary Heart Diseases › Coronary artery bypass grafting without extracorporeal circulation ... Coronary artery bypass grafting without extracorporeal circulation. Fondazione Poliambulanza is leader not only in Italy but ...
https://www.poliambulanza.it/en/areas-of-excellence/cardiovascular-area/diagnosis-and-treatment-of-coronary-heart-diseases/cardiopulmonary-bypass-without-extracorporeal-circulation
Pheochromocytoma-induced cardiogenic shock successfully treated by extracorporeal circulationPheochromocytoma-induced cardiogenic shock successfully treated by extracorporeal circulation
... Min Young Lee, Sang Bae Lee, ... Mechanical ventilation and veno-arterial extracorporeal membrane oxygenation (ECMO) were implemented owing to her unstable ...
https://www.e-jyms.org/journal/view.php?number=1910
Pediatric Extracorporeal Membrane Oxygenation: Overview, Preparation, TechniquePediatric Extracorporeal Membrane Oxygenation: Overview, Preparation, Technique
Subsequently, in some patients, the emphasis shifted to carbon dioxide removal, and the term extracorporeal carbon dioxide ... was initially used to describe long-term extracorporeal support that focused on the function of oxygenation. ... Introduction to ECMO The term extracorporeal membrane oxygenation (ECMO) ... Extracorporeal circulation for support of palliative cardiac surgery in infants. Ann Thorac Surg. 1970 Oct. 10(4):354-63. [QxMD ...
https://www.medscape.com/answers/1818617-182434/how-are-infections-controlled-in-pediatric-patients-on-ecmo
International professional associations :: Czech Society of Extracorporeal Circulation and Supporting Circulatory SystemsInternational professional associations :: Czech Society of Extracorporeal Circulation and Supporting Circulatory Systems
Copyright © 2013-2020 Czech Society of Extracorporeal Circulation and Supporting Circulatory Systems ...
https://www.english.czesect.cz/international-professional-associations/
Cortiva BioActive Surface - Overview | MedtronicCortiva BioActive Surface - Overview | Medtronic
Biocompatibility of extracorporeal circulation. In vitro comparison of heparin-coated and uncoated oxygenator circuits. J ... Why Use Biocompatible Surfaces for Extracorporeal Circulation Circuits?. Blood is naturally compatible with vascular ... Biocompatible surfaces for Medtronic extracorporeal circulation technologies mimic critical characteristics of the vascular ... covalent bond so that heparin does not leach from the surface during extracorporeal circulation in the presence of blood or ...
https://www.medtronic.com/us-en/healthcare-professionals/products/cardiovascular/cardiopulmonary/cortiva-bioactive-surface.html
Respiratory indications for ECMO: focus on COVID-19Respiratory indications for ECMO: focus on COVID-19
Extracorporeal membrane oxygenation (ECMO) is increasingly being used for patients with severe respiratory failure and has ... Keywords: ARDS; Acute respiratory distress syndrome; COVID-19; ECMO; Extracorporeal circulation; Extracorporeal membrane ... Extracorporeal membrane oxygenation (ECMO) is increasingly being used for patients with severe respiratory failure and has ...
https://pubmed.ncbi.nlm.nih.gov/35945343/
Is there a role of TNFR1 in acute lung injury cases associated with extracorporeal circulation? - PDF Download FreeIs there a role of TNFR1 in acute lung injury cases associated with extracorporeal circulation? - PDF Download Free
... and its receptors is up-regulated during extracorporeal circul... ... Key words: Extracorporeal circulation (ECC), Acute lung injury ... Is there a role of TNFR1 in acute lung injury cases associated with extracorporeal circulation?* Yu ZHAO§1, Chong-wei ZHANG§1, ... The signaling pathway for tumor necrosis factor-α (TNF-α) and its receptors is up-regulated during extracorporeal circulation ( ... 1 Introduction Acute lung injury (ALI) is one of the most common complications following extracorporeal circulation (ECC), and ...
https://docksci.com/is-there-a-role-of-tnfr1-in-acute-lung-injury-cases-associated-with-extracorpore_5af96679d64ab2b97f68692d.html
The Next Generation of Colloids: Ready for Prime Time? : Anesthesia & AnalgesiaThe Next Generation of Colloids: Ready for "Prime Time"? : Anesthesia & Analgesia
Extracorporeal circulation for open-heart surgery: pathophysiology, apparatus and methods including the special techniques of ... Techniques in extracorporeal circulation. 4th ed. London: Arnold, 2004:99-107. * Cited Here ... Heart-lung bypass: principles and techniques of extracorporeal circulation. New York, NY: Grune & Stratton, 1962:260-76. * ... Frumento R, Bennett-Guerrero E. Prime solutions for extracorporeal circulation. In: Mongero LB, Beck JR, eds. On bypass ...
https://journals.lww.com/anesthesia-analgesia/Fulltext/2009/12000/The_Next_Generation_of_Colloids__Ready_for__Prime.1.aspx
Allogeneic Blood Product Usage in Coronary Artery Bypass Grafting (CABG) with minimalized Extracorporeal Circulation System ...Allogeneic Blood Product Usage in Coronary Artery Bypass Grafting (CABG) with minimalized Extracorporeal Circulation System ...
... with minimalized Extracorporeal Circulation System (MECC) Standard On-Pump Coronary Artery Bypass Grafting ... The use of extracorporeal circulation is associated with some already mentioned adverse effects [4, 5]. The negative ... Is minimized extracorporeal circulation effective to reduce the need for red blood cell transfusion in coronary artery bypass ... Minimal extracorporeal circulation: an alternative for on-pump and off-pump coronary revascularization. Ann Thorac Surg 2009; ...
https://opencardiovascularmedicinejournal.com/VOLUME/10/PAGE/148/
Echocardiogram of the month|br|Asymptomatic descending aorta dissection after cardiac surgery using extracorporeal circulation ...Echocardiogram of the month|br|Asymptomatic descending aorta dissection after cardiac surgery using extracorporeal circulation ...
The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).. Alternatively, you can also download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link below.. If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.. ...
https://journals.viamedica.pl/kardiologia_polska/article/view/79996/60626
Search - NeL.eduSearch - NeL.edu
Circulating leptin, zinc, and copper levels after extracorporeal circulation.. Gormus Z, Gormus N, Baltaci A, Halifeoglu I, ... OBJECTIVE: The role of leptin in the acute stress response to extracorporeal circulation has been well documented, however, the ... We aimed to research the circulating leptin, zinc, and copper levels before, during, and after the extracorporeal circulation, ... CONCLUSIONS: These results indicate that circulating leptin levels increase after the extracorporeal circulation as an acute ...
https://www.nel.edu/journal/search/?keywords=Operative&vp-page=3
PRADEEP KUMAR RADHAKRISHNAN | CTSNetPRADEEP KUMAR RADHAKRISHNAN | CTSNet
Extracorporeal circulation. *Heart failure. *Mechanical circulatory assistance. *Pericardium. *Valve disease. *Tricuspid valve ...
https://www.ctsnet.org/home/rpradeep
Product Classification
Cardiovascular implants and artificial organs - Cannulae for extracorporeal circulation. *6-273 ISO 23908 First edition 2011-06 ...
https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpcd/classification.cfm?id=2808
Table - Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination - Volume...
Note patient was initiated on extracorporeal membrane oxygenation shortly after return of spontaneous circulation; ...
https://wwwnc.cdc.gov/eid/article/27/11/21-1612-t1
Mycobacterium chimaera Contamination of Heater-Cooler Devices Used in Cardiac Surgery - United States | MMWRMycobacterium chimaera Contamination of Heater-Cooler Devices Used in Cardiac Surgery - United States | MMWR
... patients had undergone open-heart surgery that used contaminated heater-cooler devices during extracorporeal circulation (1). ...
https://www.cdc.gov/mmwr/volumes/65/wr/mm6540a6.htm
Theodor Kolobow Collection Finding Aid - Office of NIH History and Stetten MuseumTheodor Kolobow Collection Finding Aid - Office of NIH History and Stetten Museum
Extra Corporeal Circulation; 3 sheets of slides, 1 handout. Giacomini Presentation, 2001; 4 sheets of slides ... There his work led to many instruments used in clinical practice today, such as Extracorporeal Membrane Oxygenation (ECMO), ... and Extracorporeal Membrane Oxygenation (ECMO). Dr. Kolobows ideas lead to many other biotechnological advances, and over the ...
https://history.nih.gov/display/history/Theodor+Kolobow+Collection+Finding+Aid
Hemoperfusion | Harvard Catalyst Profiles | Harvard CatalystHemoperfusion | Harvard Catalyst Profiles | Harvard Catalyst
Removal of toxins or metabolites from the circulation by the passing of blood, within a suitable extracorporeal circuit, over ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Hemoperfusion
Journal of the Japan Society of Blood Transfusion
Clinical and experimental studies on the changes in blood coagulability were made in extracorporeal circulation by the aid of ... STUDIES OF REPLACEMENT TRANSFUSION FOR EXTRACORPOREAL CIRCULATION. I. CHANGES IN BLOOD COAGULABILITY FOLLOWING THE USE OF ...
https://www.jstage.jst.go.jp/browse/jjtc1958/5/4/_contents/-char/en
Ralf BENSBERG | Doctor of Medicine | RWTH Aachen University, Aachen | Faculty of Medicine and University HospitalRalf BENSBERG | Doctor of Medicine | RWTH Aachen University, Aachen | Faculty of Medicine and University Hospital
A novel approach in extracorporeal circulation: Individual, integrated, and interactive heart-lung assist (I3-Assist) ... Hirudin serves as an alternative anticoagulant for extracorporeal blood circulation. Comparing anticoagulation with hirudin ( ... Pumpless arterio-venous extracorporeal lung assist compared with veno-venous extracorporeal membrane oxygenation during ... Miniaturized veno-venous extracorporeal membrane oxygenation (mECMO) and arterio-venous pumpless extracorporeal lung assist ( ...
https://www.researchgate.net/profile/Ralf-Bensberg
Treatment of refractory angina in patients not suitable for revascularization | Nature Reviews CardiologyTreatment of refractory angina in patients not suitable for revascularization | Nature Reviews Cardiology
Circulation 110, 3055-3061 (2004).. Article PubMed Google Scholar *. Wang, Y. et al. A modified regimen of extracorporeal ... Extracorporeal shock waves: from lithotripsy to anti-inflammatory action by NO production. Nitric Oxide 12, 89-96 (2005). ... Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo. ...
https://www.nature.com/articles/nrcardio.2013.200?error=cookies_not_supported&code=561428b2-dff7-4b1e-8732-5be1e25d7b73
HAN Archive - 00397|Health Alert Network (HAN)HAN Archive - 00397|Health Alert Network (HAN)
... patients had undergone open-heart surgery that used contaminated heater-cooler devices during extracorporeal circulation (1). ...
https://emergency.cdc.gov/han/han00397.asp
Malcolm MacDonald | Stanford MedicineMalcolm MacDonald | Stanford Medicine
"The Extracardiac Conduit Fontan Operation Using Minimal Approach Extracorporeal Circulation: Early and Midterm Outcomes." ,i> ... "The Extracardiac Conduit Fontan Operation Using Minimal Approach Extracorporeal Circulation: Early and Midterm Outcomes." ,i> ... than did the oxygenator group.The extracardiac conduit Fontan operation coupled with minimal use of extracorporeal circulation ... than did the oxygenator group.The extracardiac conduit Fontan operation coupled with minimal use of extracorporeal circulation ...
https://med.stanford.edu/profiles/malcolm-macdonald
Current and future applications of virtual reality technology for cardiac interventions | Nature Reviews CardiologyCurrent and future applications of virtual reality technology for cardiac interventions | Nature Reviews Cardiology
Our group is developing several VR-based simulators for extracorporeal circulation and cardiopulmonary resuscitation after ...
https://www.nature.com/articles/s41569-022-00789-4?error=cookies_not_supported&code=3f7a4891-528c-412e-b8b8-7f6cfbf69aad
Portal LIS - Localizador de Informação em SaúdePortal LIS - Localizador de Informação em Saúde
Extracorporeal Circulation 2 * Intensive Care Units 2 * Legislation, Nursing 2 * Nursing, Practical 2 ...
https://bvsalud.org/portal-lis/en/lis-search?q=Enfermer%C3%ADa&filter=descriptor:Education,+Nursing+AND+descriptor:Pesquisa+em+Enfermagem
Consumption Coagulopathy: Practice Essentials, Pathophysiology, EpidemiologyConsumption Coagulopathy: Practice Essentials, Pathophysiology, Epidemiology
... and extracorporeal circulation. In addition, factor XIIa leads to the activation of the complement system and generation of ...
http://emedicine.medscape.com/article/955059-overview
HAN Archive - 00397|Health Alert Network (HAN)HAN Archive - 00397|Health Alert Network (HAN)
... patients had undergone open-heart surgery that used contaminated heater-cooler devices during extracorporeal circulation (1). ...
https://www.emergency.cdc.gov/han/han00397.asp
Quick Facts: Plantar Fasciitis - MSD Manual Consumer VersionQuick Facts: Plantar Fasciitis - MSD Manual Consumer Version
Apply sound waves to the heel to improve your circulation and lessen the pain (extracorporeal pulse activation therapy) ...
https://www.msdmanuals.com/home/quick-facts-bone,-joint,-and-muscle-disorders/foot-problems/plantar-fasciitis
Health Alerts ArchiveHealth Alerts Archive
... patients had undergone open-heart surgery that used contaminated heater-cooler devices during extracorporeal circulation. ...
https://santacruzhealth.org/HSAHome/HealthAlerts/HealthAlertsArchive.aspx
ECMOMembraneMinimally invasiveCardiopulmonary resuscitationCoronary Artery BAcuteECLSExtra Corporeal CirculationCardiac arrestAmSECTCirculatoryPostoperativeSeverePatientBloodClinicalCongenitalThoracicInsufficiencyCarbonPatientsTechnologySystemIndividualChildren
ECMO11
  • Mechanical ventilation and veno-arterial extracorporeal membrane oxygenation (ECMO) were implemented owing to her unstable vital signs. (e-jyms.org)
  • The term extracorporeal membrane oxygenation (ECMO) was initially used to describe long-term extracorporeal support that focused on the function of oxygenation. (medscape.com)
  • Extracorporeal membrane oxygenation (ECMO) system. (medscape.com)
  • Extracorporeal membrane oxygenation (ECMO) is increasingly being used for patients with severe respiratory failure and has received particular attention during the coronavirus disease 2019 (COVID-19) pandemic. (nih.gov)
  • His work is a clear example of translational research, with laboratory developments rapidly implemented in clinical practice, and includes the membrane oxygenator used in ventilators, artificial kidneys, endotracheal tubes designs, and Extracorporeal Membrane Oxygenation (ECMO). (nih.gov)
  • There his work led to many instruments used in clinical practice today, such as Extracorporeal Membrane Oxygenation (ECMO), which has been used to treat thousands of people. (nih.gov)
  • In severe cases, this therapy may not be sufficient any more and long term extracorporeal membrane oxygenation (ECMO) may be used as a last chance rescue therapy. (researchgate.net)
  • Autoregulation may be impaired during various neonatal disease states including prematurity, hypoxic-ischemic encephalopathy (HIE), intraventricular hemorrhage, congenital cardiac disease, and infants requiring extracorporeal membrane oxygenation (ECMO). (cam.ac.uk)
  • Following these cardiac arrests, return of spontaneous circulation was restored in 7 (53.8%), circulation was restored with extracorporeal membrane oxygenation (ECMO) in 3 (23.1%), and 3 children died (23.1% of PICA events). (aap.org)
  • Only a few days after arriving at Rush, Garcia was placed on ECMO, short for extracorporeal membrane oxygenation, which uses a machine to add oxygen to the blood and remove carbon dioxide before pumping it back into circulation. (rush.edu)
  • For severe cases of PPHN, extracorporeal membrane oxygenation (ECMO) is used to maintain oxygen delivery to the body until the PVR falls. (phassociation.org)
Membrane7
  • A diagram of extracorporeal membrane oxygenation is shown below. (medscape.com)
  • In 1970, Baffes et al reported the successful use of extracorporeal membrane oxygenation as support in infants with congenital heart defects who were undergoing cardiac surgery. (medscape.com)
  • Removal of toxins or metabolites from the circulation by the passing of blood, within a suitable extracorporeal circuit, over semipermeable microcapsules containing adsorbents (e.g., activated charcoal) or enzymes, other enzyme preparations (e.g., gel-entrapped microsomes, membrane-free enzymes bound to artificial carriers), or other adsorbents (e.g., various resins, albumin-conjugated agarose). (harvard.edu)
  • Miniaturized veno-venous extracorporeal membrane oxygenation (mECMO) and arterio-venous pumpless extracorporeal lung assist (pECLA) were compared for respiratory and haemodynamic response and ext. (researchgate.net)
  • Extracorporeal membrane oxygenation can achieve sufficient gas exchange in severe acute respiratory distress syndrome. (researchgate.net)
  • Patients were excluded if they had missing data, were given any other vasopressors, or required initiation of extracorporeal membrane oxygenation to obtain return of circulation. (sccm.org)
  • Extracorporeal membrane oxygenation may be considered for patients with refractory shock. (medscape.com)
Minimally invasive3
  • Advances in extracorporeal circulation using a minimally invasive circuit have rapidly emerged, and the components and biocoatings of the minimally invasive extracorporeal circuit (MiECC) have improved. (archive.org)
  • Use of minimally invasive extracorporeal circulation (MiECC) techniques might be reasonable for reduction of CSA-AKI risk in adults undergoing cardiac surgery with CPB. (medscape.com)
  • Combining medical electrophysiological examination, all kinds of treatments such as extracorporeal circulation support, minimally invasive thoracoscopic assistance, and simultaneous or sequential surgical hybridization therapy are available. (jigsawpuzzleszone.com)
Cardiopulmonary resuscitation1
  • 2019 american heart association focused update on advanced cardiovascular life support: use of advanced airways, vasopressors, and extracorporeal cardiopulmonary resuscitation during cardiac arrest: an update to the american heart association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. (bvsalud.org)
Coronary Artery B2
  • Fondazione Poliambulanza is leader not only in Italy but also in Europe in Coronary artery bypass grafting without extracorporeal circulation with at least a 90 per cents of treatments performed in that procedure, while the average regarding other italian hospitals is about 20 per cent. (poliambulanza.it)
  • Analysis of Myocardial Ischemia Parameters after Coronary Artery Bypass Grafting with Minimal Extracorporeal Circulation and a Novel Microplegia versus Off-Pump Coronary Artery Bypass Grafting. (unibas.ch)
Acute8
  • Is there a role of TNFR1 in acute lung injury cases associated with extracorporeal circulation? (docksci.com)
  • Abstract: The signaling pathway for tumor necrosis factor-α (TNF-α) and its receptors is up-regulated during extracorporeal circulation (ECC), and recruits blood neutrophil into the lung tissue, which results in acute lung injury (ALI). (docksci.com)
  • 1 Introduction Acute lung injury (ALI) is one of the most common complications following extracorporeal circulation (ECC), and the mortality rate in its severe form, acute respiratory distress syndrome (ARDS), is very high (Ng et al. (docksci.com)
  • Veno-venous extracorporeal lung assist (ECLA) can provide sufficient gas exchange even in most severe cases of acute respiratory distress syndrome. (researchgate.net)
  • Abstract Extracorporeal life support (ECLS) is a well-established technique for the treatment of different cardiac and pulmonary diseases, e.g., congenital heart disease and acute respiratory distress syndrome. (researchgate.net)
  • Extracorporeal lung support is effective to prevent hypoxaemia and excessive hypercapnia with respiratory acidosis in acute respiratory distress syndrome. (researchgate.net)
  • Guidelines for prevention of cardiac surgery-associated acute kidney injury (CSA-AKI) were published in January 2023 by the Society of Thoracic Surgeons (STS), the Society of Cardiovascular Anesthesiologists (SCA), and the American Society of Extracorporeal Technology (AmSECT) in Anesthesia & Analgesia . (medscape.com)
  • Extracorporeal gas exchange in acute respiratory failure. (ox.ac.uk)
ECLS1
  • With all of these uses for extracorporeal circuitry, a new term, extracorporeal life support (ECLS), has come into vogue to describe this technology. (medscape.com)
Extra Corporeal Circulation3
  • Before the anesthetic induction, a partial extra-corporeal circulation was established to prevent a collapse of the circulation. (bvsalud.org)
  • Descending aortic graft replacement and following abdominal aortic graft replacement were performed safely using the partial extra-corporeal circulation to relief the afterload for the severely deteriorated left ventricle with severe mitral regurgitation. (bvsalud.org)
  • Even for a difficult patient with Marfan syndrome with severe left ventricular dysfunction and mitral regurgitation, graft replacement was feasible with meticulous perioperative circulatory management using partial extra-corporeal circulation and intra-aortic balloon pumping. (bvsalud.org)
Cardiac arrest1
  • Sodium Bicarbonate Injection, USP is indicated in the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. (nih.gov)
AmSECT1
  • The individual receiving this award must be active in the field of extracorporeal technology and must be a member of AmSECT. (amsect.org)
Circulatory1
  • A program that prepares individuals, under the supervision of physicians and nurses, to operate extracorporeal circulation and autotransfusion equipment during medical procedures and surgeries where the support or temporary replacement of a patient's own respiratory or circulatory system is required. (mymajors.com)
Postoperative2
  • Extracorporeal support was later used for postoperative support in patients following cardiac surgery. (medscape.com)
  • Intra-aortic balloon pumping was also promptly used to assist the poor circulation in the postoperative period. (bvsalud.org)
Severe1
  • In one report, almost two thirds of the patients with severe Hantavirus pulmonary syndrome, with predicted mortality of 100%, who were supported with extracorporeal circulation survived and completely recovered. (medscape.com)
Patient2
  • It is well known that the risk to the patient increases with the amount of time required on extracorporeal circulation. (justia.com)
  • Usually, during open-heart surgery, an extracorporeal circulation (ECC) is carried out on the patient. (asme.org)
Blood7
  • End Point Attachment of heparin results in a strong, covalent bond so that heparin does not leach from the surface during extracorporeal circulation in the presence of blood or albumin. (medtronic.com)
  • Because of the trauma associated with the procedure and the attendant duration of extracorporeal blood circulation, some patients do not survive the surgical procedure or die shortly thereafter. (justia.com)
  • Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation. (bvsalud.org)
  • This is typically seen as a reflection of birth events (delivery after 40 weeks gestation, meconium aspiration syndrome, infection such as Group B Streptococcus) or with congenital heart lesions, which the extra blood flow through the pulmonary circulation can stress the pulmonary blood vessels (premature closure of blood vessels, pulmonary venous abnormalities). (phassociation.org)
  • The echocardiogram is the test used to make the diagnosis of PPHN, and it will show signs of elevated right ventricular pressure and abnormal shunting of blood through persistent fetal circulation vessels. (phassociation.org)
  • Warm: Reduce the excitability of painful nerves, improve blood circulation, inhibit cell inflammation, and reduce the sensitivity of nerve endings. (shockwave-therapymachine.com)
  • Because blood flow is vital for a man's erection, it makes sense to pay attention to problems of circulation when addressing erectile dysfunction. (drelist.com)
Clinical1
  • The bioactive coating marketed by Medtronic under the name Cortiva BioActive Surface is the most researched biosurface for today's extracorporeal circulation technologies, with extensive publication of clinical and scientific evidence in peer-reviewed cardiovascular surgery, perfusion, and scientific literature. (medtronic.com)
Congenital1
  • [ 2 ] In 1954, Lillehei developed the cross-circulation technique by using slightly anesthetized adult volunteers as live cardiopulmonary bypass apparatuses during the repair of certain congenital cardiac disorders. (medscape.com)
Thoracic1
  • Posterior circulation cerebral infarcts associated with repair of thoracic aortic disruption using partial left heart bypass. (ucdenver.edu)
Insufficiency1
  • The aim of this study was to determine the preferential scheme of medical therapy in perioperative management of cardiac surgery patients with extracorporeal circulation, with IHD or with chronic heart insufficiency (CHI) from the point of view of pharmacoeconomic analysis by comparing ratios between expenses and efficacy, safety and quality of life associated with the use of Neoton (phosphocreatine) in comparison with the control group. (pharmacoeconom.com)
Carbon1
  • Subsequently, in some patients, the emphasis shifted to carbon dioxide removal, and the term extracorporeal carbon dioxide removal was coined. (medscape.com)
Patients7
  • From pediatric patients to adults, Cortiva BioActive Surface is an important component of routine as well as complex extracorporeal circulation procedures. (medtronic.com)
  • 83 patients were operated by the MECC technique and 73 were treated by standard extracorporeal circulation (sECC). (opencardiovascularmedicinejournal.com)
  • The infected patients had undergone open-heart surgery that used contaminated heater-cooler devices during extracorporeal circulation ( 1 ). (cdc.gov)
  • Fifty-nine children Ð including all the patients from group I (20) and 39 children from group II were qualified for operations in extracorporeal circulation. (medscimonit.com)
  • Results of the budget impact analysis have shown that the use of the standard therapy + phosphocreatine instead of the standard therapy itself in perioperative management of cardiac surgery patients with extracorporeal circulation, with IHD or with CHI has saved money. (pharmacoeconom.com)
  • ABSTRACT Objective: to identify the risk factors associated with cases of excessive bleeding in patients submitted to cardiac surgery with extracorporeal circulation. (bvsalud.org)
  • A more recent small study (Circulation 2013;128:1495) of patients with anterior STEMI and Killip class II or less heart failure who were undergoing PCI resulted in significantly smaller infarct size, as measured by MRI, in patients who received IV metoprolol compared to placebo. (blogspot.com)
Technology4
  • The Award of Excellence is presented to a perfusionist who has demonstrated excellent work which exemplifies creativity and intellectual originality in extracorporeal technology. (amsect.org)
  • The Perfusionist of the Year Award is presented to an individual who has demonstrated outstanding commitment to the field of extracorporeal technology during the current year. (amsect.org)
  • The individual receiving the award will have demonstrated excellence in the field of extracorporeal technology through noteworthy extracurricular or volunteering activities. (amsect.org)
  • This award is not to be presented for any one specific reason repeatedly, for there are many people in the field of extracorporeal technology making worthy contributions in a variety of areas who deserve recognition. (amsect.org)
System1
  • The objective of this study was to evaluate the ABPTs in minimalized extracorporeal cardiopulmonary (MECC TM ) compared with standard open system on-pump coronary revascularization. (opencardiovascularmedicinejournal.com)
Individual1
  • The award is designed to honor an individual who has made significant contribution(s) to the field of extracorporeal circulation. (amsect.org)
Children1
  • Children, the elderly, and diabetics are more prone to frostbite because of the size of their extremities or poor circulation. (chelseafoot.com)