Exercise Tolerance
Exercise Test
Exercise Therapy
Exercise
Physical Exertion
Drug Tolerance
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
Oxygen Consumption
Physical Endurance
Immune Tolerance
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
Breathing Exercises
Pulmonary Disease, Chronic Obstructive
Muscle, Skeletal
Lung Diseases, Obstructive
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Respiratory Function Tests
Pulmonary Gas Exchange
Angina Pectoris
Glucose Tolerance Test
Double-Blind Method
Forced Expiratory Volume
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
Anaerobic Threshold
The oxygen consumption level above which aerobic energy production is supplemented by anaerobic mechanisms during exercise, resulting in a sustained increase in lactate concentration and metabolic acidosis. The anaerobic threshold is affected by factors that modify oxygen delivery to the tissues; it is low in patients with heart disease. Methods of measurement include direct measure of lactate concentration, direct measurement of bicarbonate concentration, and gas exchange measurements.
Cross-Over Studies
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Quality of Life
Counterpulsation
A technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure. It may be achieved by intra-aortic balloon, or by implanting a special pumping device in the chest, or externally by applying a negative pressure to the lower extremities during cardiac systole.
Treatment Outcome
Hemodynamics
Walking
Respiration
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Cardiac Output
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Inspiratory Capacity
Muscle Strength
Stroke Volume
Transplantation Tolerance
Vital Capacity
Lactic Acid
Adaptation, Physiological
Oxygen
Isosorbide Dinitrate
Oxygen Inhalation Therapy
Neurocirculatory Asthenia
A clinical syndrome characterized by palpitation, SHORTNESS OF BREATH, labored breathing, subjective complaints of effort and discomfort, all following slight PHYSICAL EXERTION. Other symptoms may be DIZZINESS, tremulousness, SWEATING, and INSOMNIA. Neurocirculatory asthenia is most typically seen as a form of anxiety disorder.
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Muscle Fatigue
A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.
Ebstein Anomaly
Propanolamines
Pulmonary Ventilation
Metoprolol
Analysis of Variance
Prospective Studies
Lung
Bronchitis
Follow-Up Studies
Bicycling
Glycogen Storage Disease Type V
Adrenergic beta-Antagonists
Ventricular Function, Left
Echocardiography
Physical Fitness
Single-Blind Method
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Cardiac Output, Low
A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
Physical Conditioning, Animal
Bronchodilator Agents
Energy Metabolism
Severity of Illness Index
Nitroglycerin
Resistance Training
A type of strength-building exercise program that requires the body muscle to exert a force against some form of resistance, such as weight, stretch bands, water, or immovable objects. Resistance exercise is a combination of static and dynamic contractions involving shortening and lengthening of skeletal muscles.
Hypertension, Pulmonary
Fatigue
Ipratropium
Running
Bisoprolol
Coronary Disease
Muscle Stretching Exercises
Exercises that stretch the muscle fibers with the aim to increase muscle-tendon FLEXIBILITY, improve RANGE OF MOTION or musculoskeletal function, and prevent injuries. There are various types of stretching techniques including active, passive (relaxed), static, dynamic (gentle), ballistic (forced), isometric, and others.
Nafronyl
Echocardiography, Doppler
Respiratory Mechanics
Self Tolerance
Clinical Trials as Topic
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Lung Volume Measurements
Cardiovascular Agents
Cardiac Volume
Pulmonary Emphysema
Carbon Dioxide
Recovery of Function
Propranolol
Cardiac Pacing, Artificial
Questionnaires
Glucose Intolerance
A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
Cardiomyopathy, Dilated
Random Allocation
Heart Ventricles
Heart Diseases
Electrocardiography, Ambulatory
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
Physical Education and Training
Electric Stimulation Therapy
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Salt-Tolerance
Asthma, Exercise-Induced
Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).
Carbazoles
Dose-Response Relationship, Drug
Pacemaker, Artificial
Pilot Projects
Statistics, Nonparametric
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Exercise Movement Techniques
Dietary Supplements
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
Myocardial Infarction
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Drug Administration Schedule
Activities of Daily Living
Enalapril
Tomography, Emission-Computed, Single-Photon
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Antihypertensive Agents
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Stress, Physiological
Angiotensin-Converting Enzyme Inhibitors
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Prognosis
Body Weight
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Linear Models
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Placebos
Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.
Drug Therapy, Combination
Cardiac Catheterization
Droughts
Ventricular Remodeling
Muscle Contraction
Risk Factors
Insulin Resistance
Sports
Cardiovascular Physiological Phenomena
Administration, Inhalation
Natriuretic Peptide, Brain
Ergometry
Glucose
Obesity
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Cardiotonic Agents
Quadriceps Muscle
Peripheral Tolerance
Cross-Sectional Studies
Myocardium
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Morphine
Body Composition
Aging
Swimming
Coronary Angiography
Sweating
Fatty Acids, Nonesterified
Reference Values
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Coronary Artery Bypass
Skin Transplantation
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Dietary Carbohydrates
Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)
Pulmonary Artery
Pain Measurement
Echo derived variables predicting exercise tolerance in patients with dilated and poorly functioning left ventricle. (1/1872)
OBJECTIVE: To determine whether resting echo derived measurements predict exercise tolerance and its interrelation with heart rate response and ventilation drive in patients with systolic left ventricular disease. DESIGN: Prospective echocardiographic examination followed by cardiopulmonary exercise testing. SETTING: A tertiary referral centre for cardiac diseases. SUBJECTS: 21 patients (11 with coronary artery disease, 10 with idiopathic dilated cardiomyopathy) with end diastolic dimension > 6.4 cm, shortening fraction < 25%, and in sinus rhythm. There were 11 age matched normal controls. RESULTS: In the patients, peak oxygen consumption (mVo2) correlated with right ventricular long axis excursion (r = 0.62); 65% of the variance in mVo2 was predictable using a multivariate model with right ventricular long axis excursion and peak lengthening rate, and peak mitral atrial filling velocity as independent variables. Aetiology was not an independent predictor, although the right ventricular long axis excursion (mean (SD)) was greater in patients with idiopathic dilated cardiomyopathy than in those with coronary artery disease (2.4 (0.5) cm v 1.6 (0.5) cm, p < 0.001). Peak heart rate correlated with duration of mitral regurgitation (r = -0.52) and the slope of ventilation against CO2 production correlated with M mode isovolumic relaxation time (r = 0.61). CONCLUSIONS: In patients with systolic left ventricular dysfunction, more than half the variance in exercise tolerance can be predicted by factors measured on echocardiography at rest, particularly right ventricular long axis excursion. (+info)Cardiac metaiodobenzylguanidine uptake in patients with moderate chronic heart failure: relationship with peak oxygen uptake and prognosis. (2/1872)
OBJECTIVES: This prospective study was undertaken to correlate early and late metaiodobenzylguanidine (MIBG) cardiac uptake with cardiac hemodynamics and exercise capacity in patients with heart failure and to compare their prognostic values with that of peak oxygen uptake (VO2). BACKGROUND: The cardiac fixation of MIBG reflects presynaptic uptake and is reduced in heart failure. Whether it is related to exercise capacity and has better prognostic value than peak VO2 is unknown. METHODS: Ninety-three patients with heart failure (ejection fraction <45%) were studied with planar MIBG imaging, cardiopulmonary exercise tests and hemodynamics (n = 44). Early (20 min) and late (4 h) MIBG acquisition, as well as their ratio (washout, WO) were determined. Prognostic value was assessed by survival curves (Kaplan-Meier method) and uni- and multivariate Cox analyses. RESULTS: Late cardiac MIBG uptake was reduced (131+/-20%, normal values 192+/-42%) and correlated with ejection fraction (r = 0.49), cardiac index (r = 0.40) and pulmonary wedge pressure (r = -0.35). There was a significant correlation between peak VO2 and MIBG uptake (r = 0.41, p < 0.0001). With a mean follow-up of 10+/-8 months, both late MIBG uptake (p = 0.04) and peak VO2 (p < 0.0001) were predictive of death or heart transplantation, but only peak VO2 emerged by multivariate analysis. Neither early MIBG uptake nor WO yielded significant insights beyond those provided by late MIBG uptake. CONCLUSIONS: Metaiodobenzylguanidine uptake has prognostic value in patients with wide ranges of heart failure, but peak VO2 remains the most powerful prognostic index. (+info)Diagnostic utility of metabolic exercise testing in a patient with cardiovascular disease. (3/1872)
Disproportionate exercise limitation in patients with cardiovascular disease is a common problem faced by clinical cardiologists and other physicians. Symptoms may be attributed to psychological factors or hypothetical pathophysiological mechanisms that are difficult to confirm clinically. This case report describes how the use of metabolic exercise testing in a 28 year old woman with morphologically and haemodynamically mild hypertrophic cardiomyopathy and severe exercise limitation led to the diagnosis of an alternative cause for the patient's symptoms, namely a primary disturbance of the mitochondrial respiratory chain probably caused by a nuclear encoded gene defect. (+info)Effect of thoracotomy and lung resection on exercise capacity in patients with lung cancer. (4/1872)
BACKGROUND: Resection is the treatment of choice for lung cancer, but may cause impaired cardiopulmonary function with an adverse effect on quality of life. Few studies have considered the effects of thoracotomy alone on lung function, and whether the operation itself can impair subsequent exercise capacity. METHODS: Patients being considered for lung resection (n = 106) underwent full static and dynamic pulmonary function testing which was repeated 3-6 months after surgery (n = 53). RESULTS: Thoracotomy alone (n = 13) produced a reduction in forced expiratory volume in one second (FEV1; mean (SE) 2.10 (0.16) versus 1.87 (0.15) l; p<0.05). Wedge resection (n = 13) produced a non-significant reduction in total lung capacity (TLC) only. Lobectomy (n = 14) reduced forced vital capacity (FVC), TLC, and carbon monoxide transfer factor but exercise capacity was unchanged. Only pneumonectomy (n = 13) reduced exercise capacity by 28% (PVO2 23.9 (1.5) versus 17.2 (1.7) ml/min/kg; difference (95% CI) 6.72 (3.15 to 10.28); p<0.01) and three patients changed from a cardiac limitation to exercise before pneumonectomy to pulmonary limitation afterwards. CONCLUSIONS: Neither thoracotomy alone nor limited lung resection has a significant effect on exercise capacity. Only pneumonectomy is associated with impaired exercise performance, and then perhaps not as much as might be expected. (+info)Validity of a modified shuttle test in adult cystic fibrosis. (5/1872)
BACKGROUND: The purpose of this study was to provide some evidence of the validity of a modified shuttle test (MST) by comparing performance on the MST with peak oxygen consumption (VO2peak) measured during a treadmill test in a group of adult patients with cystic fibrosis. METHOD: Twenty patients with stable cystic fibrosis performed a ramped maximal treadmill test (STEEP protocol) and the MST using a randomised balanced design. RESULTS: The relationship between the distance achieved on the MST and VO2peak was strong (r = 0.95, p<0.01) with 90% of the variance in VO2peak explained by the variance in MST distance. The relationship was represented by the regression equation (with 95% confidence intervals) VO2peak = 6.83 (2.85 to 10.80) + 0.028 (0.019 to 0.024) x MST distance. CONCLUSION: This study provides evidence of the construct validity of the MST as an objective measure of exercise capacity in adults with cystic fibrosis. (+info)Effects of L-arginine on lower limb vasodilator reserve and exercise capacity in patients with chronic heart failure. (6/1872)
OBJECTIVE: To determine whether the reactive hyperaemic response of the lower limb increases with improved exercise capacity after acute supplementation with L-arginine, the precursor of nitric oxide, in patients with chronic heart failure. METHODS: 19 patients with chronic heart failure were enrolled in the study. Rest calf blood flow and femoral occlusion induced calf blood flow changes were measured by venous occlusion plethysmography before and after intravenous infusion of 10% L-arginine solution (5 ml/kg for 30 minutes) or placebo. Postexercise calf blood flow was also measured after the experimental infusion. During both postinfusion periods, several exercise capacity indices were determined by a symptom limited cardiopulmonary exercise test using a bicycle ergometer. RESULTS: Baseline calf blood flow, systemic blood pressure, and heart rate showed no significant changes in either of the two experimental conditions. However, the occlusion induced blood flow response was significantly enhanced by L-arginine infusion (mean (SEM) peak flow, 19.6 (1.5) v 28.9 (3.1) ml/min/dl calf tissue; p < 0.01), but not by placebo (peak flow, 19.1 (1.4) v 20.9 (1.8) ml/min/dl calf tissue; NS). Calf blood flow response after exercise was also higher after L-arginine infusion than after placebo (peak flow, 4.8 (0.4) v 6.0 (0.8) ml/min/dl calf tissue; p < 0.05). L-arginine infusion had no significant effect compared with placebo on exercise capacity indices such as peak oxygen uptake (17.1 (1.0) v 15.8 (1.1) ml/min/kg; NS), anaerobic threshold (10.5 (0.6) v 10.4 (0.7) ml/min/kg; NS), and exercise time (296 (23) v 283 (22) s; NS). CONCLUSIONS: Acute supplementation with the nitric oxide precursor L-arginine increased lower limb reactive hyperaemia but did not lead to any significant improvement in exercise capacity in patients with chronic heart failure. (+info)Ventricular dilatation in the absence of ACE inhibitors: influence of haemodynamic and neurohormonal variables following myocardial infarction. (7/1872)
OBJECTIVE: To examine the relation between patterns of ventricular remodelling and haemodynamic and neurohormonal variables, at rest and during symptom limited exercise, in the year following acute myocardial infarction in patients not receiving angiotensin converting enzyme (ACE) inhibitors. DESIGN: A prospective observational study. PATIENTS: 65 patients recruited following hospital admission with a transmural anterior myocardial infarction. METHODS: Central haemodynamics and neurohormonal activation at rest and during symptom limited treadmill exercise were measured at baseline before hospital discharge, one month later, and at three monthly intervals thereafter. PATIENTS were classified according to individual patterns of change in left ventricular end diastolic volumes at rest, assessed at each visit using transthoracic echocardiography. RESULTS: In most patients (n = 43, 66%) ventricular volumes were unchanged or reduced. Mean (SEM) treadmill exercise capacity and peak exercise cardiac index increased at month 12 by 200 (24) seconds (p < 0.001 v baseline) and by 0.8 (0.4) l/min/m2 (p<0.05 v baseline), respectively, in this group. In patients with limited ventricular dilatation (n = 11, 17%) exercise capacity increased by 259 (52) seconds (p < 0.001 v baseline) and peak exercise cardiac index improved by 0.8 (0.7) l/min/m2 (NS). In the remaining 11 patients with progressive left ventricular dilatation, exercise capacity increased by 308 (53) seconds (p< 0. 001 v baseline) and peak exercise cardiac index similarly improved by 1.3 (0.7) l/min/m2 (NS). There were trends towards increased atrial natriuretic factor (ANF) secretion at rest and at peak exercise in this group. CONCLUSIONS: Ventricular dilatation after acute myocardial infarction is a heterogeneous process that is progressive in only a minority of patients. Compensatory mechanisms, including ANF release, appear capable of maintaining and improving exercise capacity in most patients for at least 12 months, even in those with a progressive increase in ventricular size. (+info)Physiological basis of improvement after lung volume reduction surgery for severe emphysema: where are we? (8/1872)
Lung volume reduction surgery has become an accepted therapeutic option to relieve the symptoms of selected patients with severe emphysema. In a majority of these patients, it causes objective as well as subjective functional improvement. A proper understanding of the physiological determinants underlying these beneficial effects appears very important in order to better select patients for the procedure that is currently largely carried out on an empirical basis. Lung volume reduction surgery has two distinct effects. Firstly, it causes an increased elastic recoil, which at least partially explains the enhanced maximal expiratory flow. Secondly, it is associated with a reduction of hyperinflation which allows for an increase in global inspiratory muscle strength and in diaphragmatic contribution to tidal volume as well as a decrease in the inspiratory elastic load imposed by the chest wall. Taken together, these effects result in a reduced work of breathing and in an enhanced maximal ventilation which both contribute to the increased exercise capacity and reduced dyspnoea after surgery. The improved lung recoil and the reduced hyperinflation after volume reduction surgery were the primary postulates upon which the usual selection criteria for the procedure were based. It is now likely that these are correct. Nevertheless, some patients do not benefit from lung volume reduction surgery and the current literature does not allow for a refinement of the selection process from a physiological point of view. The exact mechanisms underlying the improvement in lung recoil, lung mechanics, and respiratory muscle function remain incompletely understood. Moreover, the effects of lung volume reduction surgery on gas exchange and pulmonary haemodynamics still need to be more fully investigated. An analysis of the characteristics of patients who do not benefit from the procedure and the development of an animal model for lung volume reduction surgery would probably help address these important issues. (+info)
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Exercise capacity is strongly associated with cognitive function.
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Inability to Exercise (Exercise Intolerance) Symptoms, Signs & Causes
Occupational therapy-led pulmonary rehabilitation: A practice analysis - Northumbria Research Link
NewYork-Presbyterian Queens - Pulmonary Rehabilitation
Udenafil Therapy to Improve Symptomatology, Exercise Tolerance and Hemodynamics in Patients With Mild Pulmonary Hypertension ...
How POWERbreathe could help improve exercise tolerance in people with Cystic Fibrosis - POWERbreathe
Pulmonary Rehabilitation | Inova
Simple functional exercises can assist with increasing range of moment in the forelimb of dogs<...
Exercise Treadmill Test - Medically Speaking Radio
Obesity hypoventilation syndrome
... decreased exercise tolerance and exertional chest pain may occur. On physical examination, characteristic findings are the ... In people with stable OHS, the most important treatment is weight loss-by diet, through exercise, with medication, or sometimes ...
Portable oxygen concentrator
Helps improve exercise tolerance, by allowing the user to exercise longer. Helps increase stamina throughout day-to-day ...
Homosexuality
"Submission to the Church of England's Listening Exercise on Human Sexuality". The Royal College of Psychiatrists. Retrieved 13 ... p. 2. ISBN 0-226-72988-5. "The five most improved places for gay tolerance". The Independent. London. 17 September 2008. ... ISBN 0-8057-9714-9 Boswell, John (1980), Christianity, Social Tolerance, and Homosexuality: Gay People in Western Europe from ... Robinson, B. A. (2010). "Divergent beliefs about the nature of homosexuality". Religious Tolerance.org. Retrieved 12 September ...
Freedom of religion in Singapore
"All groups have to exercise tolerance and restraint. Christians cannot expect this to be a Christian society, Muslims cannot ...
Christian J. Lambertsen
"Human tolerance and physiological responses to exercise while breathing oxygen at 2.0 ATA". Aviat Space Environ Med. 66 (4): ... September 1977). "Human tolerance to He, Ne, and N2 at respiratory gas densities equivalent to He-O2 breathing at depths to ... Lambertsen CJ (1988). "Extension of oxygen tolerance in man: philosophy and significance". Exp. Lung Res. 14 Suppl: 1035-58. ... Research in tolerance and toxicity of respiratory gasses and development of diving procedures and equipment. ...
Hydromorphone
The development of tolerance also may vary among individuals. Patients with renal abnormalities must exercise caution when ...
Lutembacher's syndrome
Reduced exercise tolerance: symptoms also caused by decreased systemic (oxygenated blood to the rest of the body) flow. Just as ... For symptoms such as loud mitral S1, pulmonary S2, mid-diastolic murmur, fatigue, reduced exercise tolerance, weight gain, ... this causes tiredness and hence a reduced exercise tolerance. Weight gain: this is commonly found in patients with large ASD ... To ensure good health, routine doctors visits, diet, weight loss, doctor-approved exercise, and use of antibiotics in dental ...
Broxyquinoline
An association with exercise intolerance has been reported. Swain R, Bapna JS (January 1986). "Impairment of exercise tolerance ...
Thermal comfort
Barwood, Martin J.; Newton, Phillip S.; Tipton, Michael J. (2009). "Ventilated Vest and Tolerance for Intermittent Exercise in ... 2012). "Skin Wettedness". Encyclopedia of Exercise Medicine in Health and Disease. p. 790. doi:10.1007/978-3-540-29807-6_3041. ... People might adapt to seasonal heat by becoming more nocturnal, doing physical activity and even conducting business at night. ... Exercise. 32 (9 Suppl): S498-504. CiteSeerX 10.1.1.524.3133. doi:10.1097/00005768-200009001-00009. PMID 10993420.. ...
Humor research
Szabo, A. (2003) The acute effects of humor and exercise on mood and anxiety. Journal of Leisure Research. (35)2, 152-162. http ... Humor's effect on pain tolerance is another point of interest within humor research. Hypotheses for this research include the ... Weaver, J., & Zillmann, D. (1994). Effect of humor and tragedy on discomfort tolerance. Perceptual and Motor Skills, 78, 632- ... Weisenberg, M., Tepper, L, & Schwarzwald, J. (1995). Humor as a cognitive technique for increasing pain tolerance. Pain, 63, ...
Caffeine
... and exercise-heat tolerance". Exercise and Sport Sciences Reviews. 35 (3): 135-40. doi:10.1097/jes.0b013e3180a02cc1. PMID ... Non-regular caffeine users have the least caffeine tolerance for sleep disruption. Some coffee drinkers develop tolerance to ... While this effect is not present during exercise-to-exhaustion exercise, performance is significantly enhanced. This is ... Tolerance varies for daily, regular caffeine users and high caffeine users. High doses of caffeine (750 to 1200 mg/day spread ...
Adolescence
These changes lead to increased strength and tolerance for exercise. Sex differences are apparent as males tend to develop " ... 1998). "Developmental changes in energy expenditure and physical activity in children: Evidence for a decline in physical ... In less restrictive cultures, there is more tolerance for displays of adolescent sexuality, or of the interaction between males ... For example, girls tend to reduce their physical activity in preadolescence and may receive inadequate nutrition from diets ...
Creatine
"Does creatine supplementation hinder exercise heat tolerance or hydration status? A systematic review with meta-analyses". ... A clinical study has shown that the intake of pure, high-quality creatine alone, or in combination with exercise, may reduce ... August 2018). "ISSN exercise & sports nutrition review update: research & recommendations". Journal of the International ... Cooper R, Naclerio F, Allgrove J, Jimenez A (July 2012). "Creatine supplementation with specific view to exercise/sports ...
Sussex Spaniel
Symptoms in puppies are generally a failure to grow and a reduced tolerance for exercise. Active treatment is effective in ...
SA8000
No interference with exercise of personnel tenets or practices; prohibition of threatening, abusive, exploitative, coercive ... Disciplinary Practices: Treat all personnel with dignity and respect; zero tolerance of corporal punishment, mental or physical ...
Atrial septal defect
Symptoms are typically decreased exercise tolerance, easy fatigability, palpitations, and syncope.[citation needed] ... shortness of breath with minimal exercise), congestive heart failure, or cerebrovascular accident (stroke). They may be noted ...
Pulmonary contusion
Dyspnea (painful breathing or difficulty breathing) is commonly seen, and tolerance for exercise may be lowered. Rapid ...
Acceptance
The exercise of power conferred by an offer by performance of some act. The act of a person to whom something is offered of ... The definition overlaps with toleration, but acceptance and tolerance are not synonyms. Acceptance - "An express act or ... which can be derived from a lack of eating or exercise. They don't sleep well, their immune systems sputter, and they even tend ...
Jyllands-Posten Muhammad cartoons controversy
Supporters said that the publication of the cartoons was a legitimate exercise in free speech: regardless of the content of the ... The Danish tradition of relatively high tolerance for freedom of speech became the focus of some attention. The controversy ... tolerance and offence have backfired on the West. Michael Neumann wrote:[193] ... ignited a debate about the limits of freedom of expression in all societies, religious tolerance and the relationship of Muslim ...
Physiological effects in space
The studies completed during Apollo, although less than optimal, left no doubt that a decrement in exercise tolerance occurred ... A significant decrement in cardiac stroke volume was associated with diminished exercise tolerance. It was not clear whether ... The astronauts' performance on the lunar surface provided no reason to believe that any serious exercise tolerance decrement ... Highly refined exercise protocols and robust exercise equipment and methods to monitor functional capacity are mandatory for ...
Parental obesity
During pregnancy, doctors recommend light exercise. Doctors state that exercise can help the comfort of the mother and the well ... For mothers, impaired glucose tolerance and hyperlipidemia are more common among obese mothers. There are many options ... Moderate forms of exercise, such as walking, can lead to healthy weight loss. Some people who are obese turn to gastric bypass ... "The Pregnant Mother: Exercise During Pregnancy". Ohio State University Medical Center. 2009. Archived from the original on 2009 ...
Glycogen storage disease type V
... taken 30 minutes prior to exercise has been shown to help improve exercise tolerance including a lower heart rate and lower ... Vissing, John; Haller, Ronald G. (2003-12-25). "The Effect of Oral Sucrose on Exercise Tolerance in Patients with McArdle's ... This is characterized by the patient's better tolerance for aerobic exercise such as walking and cycling after approximately 10 ... Supervised exercise programs have been shown in small studies to improve exercise capacity by several measures. Oral sucrose ...
Sickle cell disease
... decreased exercise tolerance, and episodes of syncope. 21% of children and 30% of adults have evidence of pulmonary ... While it has been historically recommended that people with sickle cell disease avoid exercise, regular exercise may benefit ... This also contributes to pulmonary hypertension, decreased exercise capacity, and arrhythmias. Chronic kidney failure due to ...
Fosinopril
In heart failure patients, fosinopril increases exercise tolerance and lowers the frequency of events associated with worsening ... Fosinopril attenuates clinical deterioration and improves exercise tolerance in patients with heart failure. Fosinopril ...
Postural orthostatic tachycardia syndrome
Fatigue and reduced exercise tolerance are prominent symptoms of both conditions, and dysautonomia may underlie both conditions ... such as endurance training or graded exercise therapy, can relieve symptoms for some patients.[5] Aerobic exercise performed ... In up to one third of people with POTS,[1] fainting occurs in response to postural changes or exercise.[5] Migraine-like ... Prolonged physical inactivity can worsen the symptoms of POTS.[5] Techniques that increase a person's capacity for exercise, ...
Beef
American Institute for Cancer Research (2007). Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global ... Lack of secular tolerance and caste politics has also given birth to Hindu extremist vigilante cow protection groups. Conflicts ...
Delayed onset muscle soreness
Exercise increases pain thresholds and pain tolerance. This effect, called exercise-induced analgesia, is known to occur in ... After such exercise, the muscle adapts rapidly to prevent muscle damage, and thereby soreness, if the exercise is repeated.[1][ ... Isometric (static) exercise causes much less soreness, and concentric (shortening) exercise causes none.[2]:63 ... Armstrong, RB (August 1990). "Initial events in exercise-induced muscular injury". Medicine & Science in Sports & Exercise. 22 ...
Multiple sclerosis signs and symptoms
Such impairments include fatigue, weakness, hypertonicity, low exercise tolerance, impaired balance, ataxia and tremor. ...
Type 2 diabetes
In those with impaired glucose tolerance, diet and exercise either alone or in combination with metformin or acarbose may ... A proper diet and exercise are the foundations of diabetic care,[23] with a greater amount of exercise yielding better results. ... Impaired glucose tolerance. ≥ 7.8. ≥ 140. , 7.0. , 126. 42-46. 6.0-6.4 Diabetes mellitus. ≥ 11.1. ≥ 200. ≥ 7.0. ≥ 126. ≥ 48. ≥ ... The benefit of exercise occurs regardless of the person's initial weight or subsequent weight loss.[72] High levels of physical ...
Positron emission tomography
... and so has a built-in slight direction-error tolerance). Photons that do not arrive in temporal "pairs" (i.e. within a timing- ... is that PET provides no timing information about muscle activation because it has to be measured after the exercise is ...
Music therapy
The dancing exercise is a "thank you" for the healing and tribute to the spiritual greater beings. The dance is accompanied by ... and develop tolerance and empathy.[18] Group sessions that emphasize cooperation and cohesion can be effective in working with ... feel emotionally relieved because the priest has announced them clean and subjected them to a rigorous dancing exercise. ...
Observational learning
Research Quarterly for Exercise and Sport. 63 (3): 292-301. doi:10.1080/02701367.1992.10608745. PMID 1513960.. ... Communities that participate in observational learning promote tolerance and mutual understand of those coming from different ...
糖尿病 - 維基百科,自由的百科全書
Exercise and disease management 2nd ed. Boca Raton: CRC Press. : 25. ISBN 978-1-4398-2759-8.. 引文格式1維護:冗餘文本 (link) ... 糖耐量受損(英語:Impaired glucose tolerance). ≥7.8(≥140). ,7.0(,126). 6.0-6.4. ...
Maria Theresa
... she wrote to all of her children at least once a week and believed herself entitled to exercise authority over her children ... Freedom of religion was granted only in the Declaration of Tolerance issued by Joseph immediately after Maria Theresa´s death.[ ...
多囊卵巢綜合症 - 维基百科,自由的百
Glucose tolerance testing (GTT) instead of fasting glucose can increase diagnosis of impaired glucose tolerance and frank ... the role of exercise and diet. Seminars in Reproductive Medicine (Review). 2009, 27 (4): 306-15. PMID 19530064. doi:10.1055/s- ... Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta- ... 2-Hour oral glucose tolerance test (GTT) in women with risk factors (obesity, family history, history of gestational diabetes)[ ...
History of European Jews in the Middle Ages
Most fled to Poland, as it had a reputation for religious tolerance unparalleled during this era. This religious tolerance may ... and when these attempts failed they were ever more and more restricted in the exercise of their civil rights. Soon they were ...
நீரிழிவு நோய் (இரண்டாவது வகை) - தமிழ் விக்கிப்பீடியா
"Exercise or exercise and diet for preventing type 2 diabetes mellitus". Cochrane Database Syst Rev (3): CD003054. doi:10.1002/ ... "Lifestyle interventions reduced the long-term risk of diabetes in adults with impaired glucose tolerance". Evid Based Med 13 (6 ... O'Gorman, DJ; Krook, A (2011 Sep). "Exercise and the treatment of diabetes and obesity". The Medical clinics of North America ... 33.0 33.1 33.2 Zanuso S, Jimenez A, Pugliese G, Corigliano G, Balducci S (March 2010). "Exercise for the management of type 2 ...
White blood cell
Stress - exercise, surgery, general stress. *Medication induced - corticosteroids (for example, prednisone, β-agonists, lithium ... exercise, environment, and exposure to allergens.[15] Eosinophilia is never a normal lab finding. Efforts should always be made ...
Lesbian
... s are more likely to exercise regularly than heterosexual women, and lesbians do not generally exercise for aesthetic ... Vincent Millay and social host Mabel Dodge were known for their affairs with women and promotion of tolerance of homosexuality. ... The novel included a foreword by Havelock Ellis and was intended to be a call for tolerance for inverts by publicizing their ... which promoted tolerance for homosexuals in Germany, welcomed lesbian participation, and a surge of lesbian-themed writing and ...
Vitamin C
September 13, 2010). Ascorbate-Glutathione Pathway and Stress Tolerance in Plants. Springer. p. 324. ISBN 978-9-048-19403-2. . ... function of the immune system during and after extreme physical exercise (ID 144), non-haem iron absorption (ID 132, 147), ...
Jehovah's Witnesses
Ontario Consultants on Religious Tolerance. Retrieved 27 December 2017.. "Religious Landscape Study". Pew Research Center's ... "Imitate Jehovah-Exercise Justice and Righteousness". The Watchtower. August 1, 1998. p. 16.. ...
Radiation therapy
Nieder C, Milas L, Ang KK (2000). "Tissue tolerance to reirradiation". Semin Radiat Oncol. 10 (3): 200-9. doi:10.1053/srao. ... 1954 Totskoye nuclear exercise. *Bikini Atoll. *Hanford Site. *Rocky Flats Plant. *1945 Atomic bombings of Hiroshima and ... The salivary glands and tear glands have a radiation tolerance of about 30 Gy in 2 Gy fractions, a dose which is exceeded by ...
Tomato
... disease tolerance, pest tolerance, nutritional value, and numerous other traits.[citation needed] ... "A systematic review of dietary, nutritional, and physical activity interventions for the prevention of prostate cancer ... and tolerance/resistance to various environmental pressures, including disease.[43][44] However, these breeding efforts have ...
Hyperhidrosis
... decrease in heart rate both at rest and during exercise, resulting in decreased exercise tolerance.[39] ... "Infra-stellate upper thoracic sympathectomy results in a relative bradycardia during exercise, irrespective of the operated ...
Old age
Muriel R. Gillick, a baby boomer, accuses her contemporaries of believing that by proper exercise and diet they can avoid the ... "little tolerance for older persons and very few reservations about harboring negative attitudes" about them.[113] ... One exercise was to lay out 3 sets of 5 slips of paper. On set #1, write your 5 most enjoyed activities; on set #2, write your ...
Health
Exercise. Main article: Exercise. Physical exercise enhances or maintains physical fitness and overall health and wellness. It ... Stress management is the application of methods to either reduce stress or increase tolerance to stress. Relaxation techniques ... "4 Types of Exercise". Go4Life, National Institute on Aging, US National Institutes of Health. 15 May 2014.. ... According to the National Institutes of Health, there are four types of exercise: endurance, strength, flexibility, and balance ...
Posttraumatic stress disorder
Exercise, sport and physical activity. Physical activity can influence people's psychological[193] and physical health.[194] ... tolerance (i.e., short-term benefits wearing off with time), and withdrawal syndrome; additionally, individuals with PTSD (even ... They recommend a discussion with a doctor before starting an exercise program.[195] ... The U.S. National Center for PTSD recommends moderate exercise as a way to distract from disturbing emotions, build self-esteem ...
Vasospasm
Tolerance may also develop over time due compensatory response of the body, as well as depletion of -SH groups of glutathione ... physical activity, and control for other risk factors including diabetes, obesity, and hypertension. Pharmacological therapies ...
Opinion poll
In 1916, The Literary Digest embarked on a national survey (partly as a circulation-raising exercise) and correctly predicted ...
Glossary of firearms terms
live fire exercise or LFX: Any exercise that simulates a realistic scenario for the use of specific equipment. In the popular ... This refers to parts that are designed and manufactured such that they have a relatively tight-tolerances and high level of ...
நாட்பட்ட நுரையீரல் அடைப்பு நோய் - தமிழ் விக்கிப்பீடியா
... dyspnoea and exercise tolerance in COPD". Eur Respir J 23 (6): 832-40. doi:10.1183/09031936.04.00116004. பப்மெட்:15218994. http ... Celli BR, Cote CG, Marin JM, et al. (March 2004). "The body-mass index, airflow obstruction, dyspnea, and exercise capacity ... 64.0 64.1 O'Donnell DE (2006). "Hyperinflation, Dyspnea, and Exercise Intolerance in Chronic Obstructive Pulmonary Disease". ... Exercise capacity) பயன்படுகிறது. இது எஃப்ஈவி யை பொறுத்து பூஜ்யத்திலிருந்து பத்து வரை மதிப்பெண் கொடுக்கிறது 1, உடல்நிறை ...
Teachings of Falun Gong
The Third Exercise: Penetrating the Two Cosmic Extremes:. The principles of this exercise, as stated in Falun Gong, are: "This ... Ontaria Consultants on Religious Tolerance. "INTRODUCTION TO FALUN GONG & FALUN DAFA Its terminology, symbol, texts, beliefs, ... The Fourth Exercise: Falun Heavenly Circuit:. Falun Gong says the fourth exercise is "intermediate-level". "On the basis of the ... This exercise is a tranquil standing meditation composed of four standing stances. The book Falun Gong states that the exercise ...
Ataxia
... it is important that the individual be prescribed and regularly engage in a supplementary home exercise program that ... Tolerance/intolerance. *Weight. *Beverage-specific *Beer: Potomania. *Red wine: Red wine headache ... physical therapy should include an exercise program addressing five components: static balance, dynamic balance, trunk-limb ...
Phentermine
Rare cases of pulmonary hypertension and cardiac valvular disease have been reported.[12] Tolerance usually occurs; however, ... Phentermine is used for a short period of time to promote weight loss, if exercise and calorie reduction are not sufficient, ... is a medication used together with diet and exercise to treat obesity.[3] It is taken by mouth for up to a few weeks.[3] After ... and in addition to exercise and calorie reduction.[4][12]. Phentermine is approved for up to 12 weeks of use and most weight ...
Acute lymphoblastic leukemia
"Aerobic physical exercise for adult patients with haematological malignancies". The Cochrane Database of Systematic Reviews. 1 ... asparaginase (better tolerance in people in pediatric care). *daunorubicin (used in Adult ALL) ...
Sexual identity
... identity tolerance, (4) identity acceptance, (5) identity pride, and (6) identity synthesis.[42] Fassinger's model of gay and ...
اکسیژن - ویکیپدیا، دانشنامهٔ آزاد
Webb JT; Olson RM; Krutz RW; Dixon G; Barnicott PT (1989). "Human tolerance to 100% oxygen at 9.5 psia during five daily ... Available studies support a performance boost from oxygen enriched mixtures only if it is breathed during aerobic exercise.[106 ...
Mandell Creighton
Creighton, Mandell (1906), Persecution and Tolerance: Hulsean Lectures, University of Cambridge, 1893-94, London, New York and ... As Creighton was popular with students, he was looked upon as someone who would exercise that leadership. He proceeded to do so ... Among his addresses were the Hulsean Lectures at Cambridge in the winter of 1893-94 on "Persecution and Tolerance", the 1895 ... Walking gave him many opportunities to exercise his abiding curiosity in the local botany and architecture. The habit was to ...
Factors limiting exercise tolerance in chronic lung diseases. - PubMed - NCBI
Factors limiting exercise tolerance in chronic lung diseases.. Vogiatzis I1, Zakynthinos S. ... As exercise intolerance in COPD is recognized as being multifactorial, the impacts of the following factors on patients ... A great deal of emphasis is given, however, to causes of exercise intolerance in COPD mainly because of the plethora of ... The major limitation to exercise performance in patients with chronic lung diseases is an issue of great importance since ...
Improved exercise performance and tolerance
Oral taurine improves critical power and severe-intensity exercise tolerance. - PubMed - NCBI
Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema. | The BMJ
Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema. Br Med J (Clin Res Ed) 1981; 283 :878 ... The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 ... Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema.. Br Med J (Clin Res Ed) 1981; 283 doi: https://doi. ... of carboxyhaemoglobin frequently found in bronchitic patients who smoke may reduce their tolerance of everyday exercise, ...
Exercise Tolerance Test and Exercise for Desaturation Test
Exercise for Desaturation Tests), including what the test is, how to prepare for the test, and whats done during the test. ... Answers to common questions and concerns regarding Exercise Tolerance Tests ( ... Exercise Tolerance Test and Exercise for Desaturation Test. What is Exercise Tolerance testing?. The exercise tolerance test ... Exercise Tolerance Test. If you are doing the exercise tolerance test, you will be asked to ride a stationary bicycle. You will ...
Effect of attitudes and beliefs on exercise tolerance in chronic bronchitis. | The BMJ
Effect of attitudes and beliefs on exercise tolerance in chronic bronchitis. Br Med J (Clin Res Ed) 1983; 286 :171 ... Subjective perception of exertion was most closely correlated with exercise tolerance. The distance walked in a 12-minute ... In 50 patients with chronic bronchitis the relation was assessed between exercise tolerance and pulmonary function and ... Ventilatory capacity was significantly correlated with but a poor predictor of exercise tolerance. ...
Exercise Tolerance Test | Hospice
What is an Exercise Tolerance Test?. An exercise tolerance test lets the physician see how well your heart functions when it ... An exercise tolerance test is usually safe. There is a small amount of risk because the heart is being stressed. These risks ... When the exercise portion of the test is over, your EKG and blood pressure will continue to be monitored for several minutes. ... You will exercise on a treadmill while your EKG and blood pressure are monitored. ...
Exercise tolerance testing after myocardial infarction | Clinical | Nursing Times
Exercise tolerance and alcohol intake. Blood pressure relation. | Hypertension
... heavy drinkers in high exercise tolerance categories had no higher blood pressure than nondrinkers in low exercise tolerance ... Exercise tolerance was determined by maximal treadmill exercise testing and was categorized into six age-specific by sex- ... Exercise tolerance and alcohol intake. Blood pressure relation.. G H Hartung, H W Kohl, S N Blair, S J Lawrence, R B Harrist ... Exercise tolerance and alcohol intake. Blood pressure relation.. G H Hartung, H W Kohl, S N Blair, S J Lawrence and R B Harrist ...
Exercise tolerance and cardiorespiratory adjustments at peak work capacity in cystic fibrosis
Exercise tolerance and cardiorespiratory adjustments at peak work capacity (PWC) were determined in 20 patients with cystic ... Exercise tolerance and cardiorespiratory adjustments at peak work capacity in cystic fibrosis Am Rev Respir Dis. 1982 Aug;126(2 ... there are decreases in exercise tolerance and cardiorespiratory reserves, exercise-induced ventilation-perfusion abnormalities ... Exercise tolerance and cardiorespiratory adjustments at peak work capacity (PWC) were determined in 20 patients with cystic ...
Oxidative Capacity and Exercise Tolerance in Ambulatory SMA - Tabular View - ClinicalTrials.gov
Oxidative Capacity and Exercise Tolerance in Ambulatory SMA. Official Title Evaluation of Oxidative Capacity and Exercise ... Oxidative Capacity and Exercise Tolerance in Ambulatory SMA. The safety and scientific validity of this study is the ... Participants will undergo an exercise stress test performed by a clinical exercise physiologist using an electronically-braked ... The presence of any contraindication to exercise according the ACSM criteria.. Patients with and without Spinraza treatment are ...
An Evaluation of Exercise Tolerance in Asthmatic Patients - Tabular View - ClinicalTrials.gov
Elon Musk: Balancing Purpose and Risk; Risk Tolerance Exercise -
Supplement
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Fat Plays a Vital Role After Exercise in Improving Glucose Tolerance
... fats release proteins into the bloodstream that improves glucose tolerance. ... Exercise training causes dramatic changes to fat, where these trained ... Exercise and Fitness. Exercise is about revamping your lifestyle, not just weight loss. Exercise to get healthy - that way, ... Not only did exercise-stimulated TGF-beta 2 improve glucose tolerance, treating obese mice with TGF beta 2 lowered blood lipid ...
Weight Loss, Exercise Tolerance Play Key Role in Making Hernia Surgeries Successful
Researchers wanted to learn if patients following a pre-surgical program of weight management and exercise tolerance can have ... Exercise and Fitness. Exercise is about revamping your lifestyle, not just weight loss. Exercise to get healthy that way, you ... Exercise To Gain Weight. Are you underweight and want to know how to gain weight? Exercise or workouts can help you gain weight ... A pre-surgical program of weight management and exercise tolerance can have greater success from the first surgery for ventral ...
Aortic Distensibility Independently Affects Exercise Tolerance in Patients With Dilated Cardiomyopathy | Circulation
Aortic Distensibility Independently Affects Exercise Tolerance in Patients With Dilated Cardiomyopathy. Stefano Bonapace, ... Aortic Distensibility Independently Affects Exercise Tolerance in Patients With Dilated Cardiomyopathy. Stefano Bonapace, ... Aortic Distensibility Independently Affects Exercise Tolerance in Patients With Dilated Cardiomyopathy. Stefano Bonapace, ...
Quantifying intervention-related improvements in exercise tolerance | European Respiratory Society
tolerance time. The extent to which a therapeutic strategy improves exercise tolerance in a subject with impaired physiological ... Costes F, Agresti A, Court-Fortune I, et al. Noninvasive ventilation during exercise training improves exercise tolerance in ... Puente-Maestu L, Santa Cruz A, Vargas T, et al. Effects of training on the tolerance to high-intensity exercise in patients ... But, of course, determining the exercise tolerance time at a work rate which is double that of the critical power is quite ...
Winter Blues? Study Suggests Exercise Builds both Fitness and Cold Tolerance | College of Biological Science
Winter Blues? Study Suggests Exercise Builds both Fitness and Cold Tolerance. By Daniel Cervone ... and whether exercise could improve the mouses tolerance.. "It is now recognized that white fat can become browner - sometimes ... Mice that were able to exercise daily leading up to the cold test had a higher body temperature and lost less weight in their ... "It appears that simply exercise training muscle may help mice better respond to the cold by contributing to more efficient ...
Cardiac mechanisms underlying normal exercise tolerance : gender impact
The aim of this study is to test our hypothesis that normal exercise tolerance differs according to gender and to identify ... Cardiac mechanisms underlying normal exercise tolerance: gender impact. Lindqvist, Per Umeå University, Faculty of Medicine, ... Exercise echocardiography, Gender, Filling pressure, Speckle tracking echocardiography National Category Physiology Sport and ... These native normal differences between genders may explain the known vulnerability of women to endurance exercise compared to ...
How the Colonies in America Moved from 'Tolerance' to 'Free Exercise' of Religion
How the Colonies in America Moved from "Tolerance" to "Free Exercise" of Religion Justin Taylor , September 9, 2016 ... This move-from "tolerance" to "free exercise"-set off a back-and-forth that lasted over a decade. Formal disestablishment came ... Tolerance based solely on the governments benevolence lasts only as long, and as far, as the benevolence does. Dont blink; ... George Mason had drafted a key line: "all Men should enjoy the fullest Toleration in the Exercise of Religion, according to the ...
Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled...
Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ... Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ... Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ... Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ...
Essential Amino Acids and Exercise Tolerance in Elderly Muscle-Depleted Subjects with Chronic Diseases: A Rehabilitation...
increased their exercise tolerance (bicycle exercise test) by 23% watts following 1-month EAA supplementation. In placebo ... The benefit of EAAs for exercise tolerance was confirmed by two investigations performed in ambulatory CHF patients. In the ... EAAs and Exercise in CHF Subjects (Table 2). Three investigations reported that it is possible to increase exercise capacity of ... Essential Amino Acids and Exercise Tolerance in Elderly Muscle-Depleted Subjects with Chronic Diseases: A Rehabilitation ...
Browsing by Subject "Exercise Tolerance"
Provoked exercise desaturation in patent foramen ovale and impact of percutaneous closure. Devendra, Ganesh P; Krasuski, ... Magnitude of spinal muscle damage is not statistically associated with exercise-induced low back pain intensity. Arpan, I; ... OBJECTIVES: This study was designed to assess the prevalence of provoked exercise desaturation (PED) in patients with patent ...
Frontiers | Caffeine Ingestion With or Without Low-Dose Carbohydrate Improves Exercise Tolerance in Sedentary Adults | Nutrition
Our purpose was to determine if these ergogenic aids are also effective to improve exercise tolerance in age-matched sedentary ... Our purpose was to determine if these ergogenic aids are also effective to improve exercise tolerance in age-matched sedentary ... LCHO did not benefit exercise tolerance compared to PLA and was less effective (p,0.05) compared to CAF+LCHO for all ... LCHO did not benefit exercise tolerance compared to PLA and was less effective (p p p ...
The enduring impact of social factors on exercise tolerance in men attending cardiac rehabilitation.
... exercise tolerance. The relationship of sociodemographic factors to social support was examined, as well as the role of social ... Specifically, older individuals had poorer exercise tolerance, whereas those with more income had better exercise tolerance. ... Exercise Tolerance*. Follow-Up Studies. Heart Diseases / epidemiology, physiopathology*, rehabilitation*. Humans. Male. Middle ... An exercise tolerance test was completed upon entry into cardiac rehabilitation, after 14 weeks, and after 9 months. RESULTS: ...
50 Diagnostic role of exercise tolerance testing in familial premature sudden cardiac death | Heart
Exercise tolerance test demonstrating dynamic Brugada ECG pattern. Stage 1 of Bruce protocol exercise (left) and post-exercise ... Aim We determined the diagnostic yield of exercise tolerance testing (ETT) in investigation of inherited cardiac conditions ... 50 Diagnostic role of exercise tolerance testing in familial premature sudden cardiac death ... 50 Diagnostic role of exercise tolerance testing in familial premature sudden cardiac death ...
Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control. - Full Text View - ClinicalTrials.gov
Experimental: Exercise-immediate Breakfast followed by exercise and an immediate OGTT. Behavioral: Exercise Exercise at 55% of ... Breakfast followed by exercise and a delayed (1 h) OGTT.. Behavioral: Exercise Exercise at 55% of maximum power output for 30 ... Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.. The safety and scientific validity of ... Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.. ...
Six-minute stepper test: a valid clinical exercise tolerance test for | COPD
Keywords: 6-minute stepper test, 6-minute walk test, exercise tolerance, pulmonary rehabilitation, cardiopulmonary exercise ... The results of this study show that the 6MST is a valid test to evaluate exercise tolerance in COPD patients. The use of this ... Exercise tolerance testing is an integral part of the pulmonary rehabilitation (PR) management of patients with chronic ... and cardiopulmonary exercise testing (CPET) in a cohort of COPD patients.Methods: Ninety-one COPD patients managed by ...
Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD | European Respiratory Society
Changes in exercise parameters, measured at rest, isotime and peak exercise on days 0, 21 and 42 from pretreatment exercise ... Three main time-points were used for evaluation of exercise parameters, i.e. pre-exercise rest, isotime and peak exercise. " ... dyspnoea and exercise tolerance in COPD. D.E. ODonnell, T. Flüge, F. Gerken, A. Hamilton, K. Webb, B. Aguilaniu, B. Make, H. ... which examined the effects of ipratropium on exercise tolerance in COPD 6, acute reductions in IC from rest to end of exercise ...
Improves exerciseTreadmillIntoleranceCOPDSignificantlyMETHODSSymptomsDyspneaBaselinePulmonary functionGlucoseCoronaryTestMaximalPeak exerciseFatigueUptakePhysiologicalCONCLUSIONSSkeletal muscleIntensityRehabilitationInspiratory6MWTPhysiologyAerobicEvaluateCardiac output during eChronic heart fAnginaHyperinflationCystic fibrosisCapacityMechanismsCardiovascularArterialDurationDesaturationImproveImprovementsExertionMetabolicMyocardial infarctionPhysicalIncreasesIndividualsAbnormalitiesDiastolicImprovementStrenuousResults
Improves exercise6
- The extent to which a therapeutic strategy improves exercise tolerance in a subject with impaired physiological function is considered to be a reflection of both the utility of the intervention and of its effectiveness. (ersjournals.com)
- CONCLUSION: In COPD patients with low PEF, pursed-lip breathing reduces dynamic hyperinflation and improves exercise tolerance, breathing pattern and arterial oxygenation at submaximal intensity exercise. (minervamedica.it)
- Ferracini Cabral L, Elia DC, De Sousa Marins D, Araujo Zin W, Silva Guimarães F. Pursed lip breathing improves exercise tolerance in COPD: a randomized crossover study. (minervamedica.it)
- 3, 4-Dihydroxycinnamic Acid Attenuates the Fatigue and Improves Exercise Tolerance in Rats. (nutrientjournal.com)
- Treatment with Orkambi significantly improves exercise tolerance in adult cystic fibrosis patients with severe disease as early as 4 weeks after treatment - as shown by results of the six-minute walk test (6MWT), a study found. (cysticfibrosisnewstoday.com)
- Objectives: We tested the hypothesis that intravenous iron improves exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure (CHF) and iron deficiency. (elsevier.com)
Treadmill12
- If you are doing the exercise for desaturation test, you will be asked to walk on a treadmill at a comfortable pace for a maximum of 6 minutes per exercise period. (nationaljewish.org)
- You will exercise on a treadmill while your EKG and blood pressure are monitored. (wregional.com)
- Exercise tolerance was determined by maximal treadmill exercise testing and was categorized into six age-specific by sex-specific levels. (ahajournals.org)
- Exercise tolerance was assessed by treadmill time, and changes in diastolic function were quantified by transmitral flow (E/A ratio). (onlinejacc.org)
- The primary endpoint was total exercise duration in the modified Bruce treadmill test at the 6-month follow-up. (ovid.com)
- Conclusion The total exercise duration in the modified Bruce treadmill test at the 6-month follow-up did not differ significantly in patients treated with CSWT compared with optimal medical therapy alone. (ovid.com)
- VO2 max (maximal oxygen consumption during maximal physical exercise and is measured by exercise tolerance test or Bruce test with walking on treadmill) and diastolic function of 8-scssion group. (thefreedictionary.com)
- An exercise tolerance test measures your heart's rhythm and electrical activity and your blood pressure during exercise, and takes place on a treadmill within the clinic. (dorsetheartclinic.co.uk)
- You will then be asked to exercise on a treadmill or on an exercise bike. (almondsburysurgery.nhs.uk)
- The exercise starts at a very easy pace, and is gradually made more strenuous by increasing the speed and incline of the treadmill, or by putting some resistance on the bike wheel. (almondsburysurgery.nhs.uk)
- Our pediatric exercise laboratory uses a stationary bicycle or a treadmill. (rochester.edu)
- During an exercise tolerance (stress) test, the person walks at an increasingly rapid pace on a treadmill. (msdmanuals.com)
Intolerance36
- A great deal of emphasis is given, however, to causes of exercise intolerance in COPD mainly because of the plethora of research findings that have been published in this area and also because exercise intolerance in COPD has been used as a model for understanding the interactions of different pathophysiologic mechanisms in exercise limitation. (nih.gov)
- Exercise intolerance remains problematic in subjects with chronic heart failure (CHF) and/or chronic obstructive pulmonary disease (COPD). (hindawi.com)
- The 3 studies consistently showed that elderly CHF and COPD improved exercise intolerance after 1-3 months of EAA supplementation (8 g/d). (hindawi.com)
- EAA mechanisms explaining improved exercise intolerance could be increases in muscle aerobic metabolism, mass and function, and improvement of tissue insulin sensitivity (the latter only for the CHF population). (hindawi.com)
- Early onsets of fatigue and/or dyspnea are the symptoms responsible for this exercise intolerance. (hindawi.com)
- Exercise intolerance, accentuated in the elderly because of aging body changes, negatively impacts both functional and life prognosis. (hindawi.com)
- In CHF, it is exercise intolerance and not heart function which is the most important prognostic factor [ 5 ], which furthermore is more accurate than hemodynamic/ventilator profiles at predicting outcomes [ 5 ]. (hindawi.com)
- Therefore, improved exercise intolerance of CHF/COPD patients is a key for maintaining the subjects' autonomy and quality of life as well as for increasing survival. (hindawi.com)
- If I don't take the time off to recover I get the severe exercise intolerance. (dinet.org)
- In summary, CK-2127107 increases exercise performance in this heart failure model, suggesting that modulation of skeletal muscle function by a fast skeletal troponin activator may be a useful therapeutic in heart failure-associated exercise intolerance. (aspetjournals.org)
- The impact of progressive dyspnea, fatigue, exercise intolerance, and recurrent exacerbations in patients with COPD can be devastating to their quality of life. (jaoa.org)
- Dyspnea and exercise intolerance are the two most common complaints from patients with COPD, who also have to cope with exacerbations and remissions. (jaoa.org)
- The main causes of exercise intolerance are angina pectoris due to myocardial ischemia, dyspnea in congestive heart failure due to loss of muscle mass, and muscular dysfunction or valvular disease. (springer.com)
- Besides the heart, peripheral arterial occlusive disease is a major cause for exercise intolerance. (springer.com)
- Furthermore, the degree of exercise intolerance in pALS might correlate with the reduction in the number and effectiveness of functional mitochondria able to guarantee an adequate O 2 extraction at the skeletal muscles 5 . (nature.com)
- Exercise intolerance, the reduced ability to perform activities that involve dynamic movement of large skeletal muscles because of dyspnea or fatigue, may be one of the first symptoms experienced by patients with heart failure. (aafp.org)
- The impairment in endothelial-dependent vasodilation correlates with the degree of exercise intolerance and severity of New York Heart Association class. (aafp.org)
- Anaerobic metabolism that occurs early during exercise in patients with heart failure is likely an important cause of exercise intolerance. (aafp.org)
- Exercise intolerance is a condition of inability or decreased ability to perform physical exercise at the normally expected level or duration for people of that age, size, sex, and muscle mass. (wikipedia.org)
- Exercise intolerance is not a disease or syndrome in and of itself, but can result from various disorders. (wikipedia.org)
- Dysfunctions involving the pulmonary, cardiovascular or neuromuscular systems have been frequently found to be associated with exercise intolerance, with behavioural causes also playing a part. (wikipedia.org)
- For example, a person with exercise intolerance after a heart attack may not be able to sustain the amount of physical activity needed to walk through a grocery store or to cook a meal. (wikipedia.org)
- Chronic pain that makes a person unwilling to undertake a physical activity is not, by itself, a form of exercise intolerance. (wikipedia.org)
- Objective tests for exercise intolerance normally involve performing some exercise. (wikipedia.org)
- In the six-minute walk test, the goal is to see how far the person can walk, with approximately 600 meters being a reasonable outcome for an average person without exercise intolerance. (wikipedia.org)
- The CPET test measures exercise capacity and help determine whether the cause of exercise intolerance is due to heart disease or to other causes. (wikipedia.org)
- People who experience significant fatigue before reaching the anaerobic threshold usually have a non-cardiac cause for exercise intolerance. (wikipedia.org)
- Multiple sclerosis Cystic fibrosis: CF can cause skeletal muscle atrophy, however more commonly it can cause exercise intolerance. (wikipedia.org)
- The exercise intolerance is associated with reduced pulmonary function that is the origin of CF. Bronchiectasis Post-exertional malaise is one of the main symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (wikipedia.org)
- OI includes exercise intolerance as one of the main symptoms. (wikipedia.org)
- Exercise intolerance is present in those with PCS however their intolerance to exercise may reduce over time. (wikipedia.org)
- Individuals with postconcussion syndrome may also experience a level of exercise intolerance, however there is little known comparatively about exercise intolerance in PCS patients. (wikipedia.org)
- Angina pectoris Heart failure: Exercise intolerance is a primary symptom of chronic diastolic heart failure. (wikipedia.org)
- dyspnea and fatigue, these systems consequently contribute to exercise intolerance. (wikipedia.org)
- In the heart the right ventricular (RV) can have a volume overload which ultimately produces a pressure overload in the RV resulting in exercise intolerance as the RV is no longer able to control high pressure associated with exercise. (wikipedia.org)
- Chronic heart failure Spinal muscular atrophy: symptoms include exercise intolerance, cognitive impairment and fatigue. (wikipedia.org)
COPD11
- Patients with chronic heart failure (CHF) and/or chronic obstructive pulmonary disease (COPD) often have reduced exercise tolerance, limiting participation in daily activities. (hindawi.com)
- Exercise tolerance testing is an integral part of the pulmonary rehabilitation (PR) management of patients with chronic obstructive pulmonary disease (COPD). (dovepress.com)
- The aim of this study was to compare the results of the 6MST to those obtained during a 6-minute walk test (6MWT) and cardiopulmonary exercise testing (CPET) in a cohort of COPD patients. (dovepress.com)
- The results of this study show that the 6MST is a valid test to evaluate exercise tolerance in COPD patients. (dovepress.com)
- The measurement of operating lung volumes ( i.e. end-expiratory (EELV) and end-inspiratory lung volumes) during exercise is relevant to the understanding of the impairment-disability interface in chronic obstructive pulmonary disease (COPD) 8 . (ersjournals.com)
- These factors together would improve exercise performance in COPD. (ersjournals.com)
- Exercise limitation, dynamic hyperinflation, and exertional dyspnea are key features of symptomatic chronic obstructive pulmonary disease (COPD). (dovepress.com)
- We assessed the effects of glycopyrronium bromide (NVA237), a once-daily, long-acting muscarinic antagonist, on exercise tolerance in patients with moderate to severe COPD. (dovepress.com)
- BACKGROUND: Although pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest, the evidence of its effects on dynamic hyperinflation (DH) and exercise tolerance is scarce. (minervamedica.it)
- AIM:To evaluate the effect of PLB on exercise tolerance, breathing pattern, dynamic hyperinflation and arterial oxygenation in COPD patients during high-intensity exercise. (minervamedica.it)
- CLINICAL REHABILITATION IMPACT: This study points to a possible application of PLB in a selected group of COPD patients aiming at improving the exercise tolerance. (minervamedica.it)
Significantly11
- Ventilatory capacity was significantly correlated with but a poor predictor of exercise tolerance. (bmj.com)
- The distance walked in a 12-minute exercise test was significantly correlated with measurements of mood and with several attitudes and beliefs. (bmj.com)
- Both systolic and diastolic blood pressure were significantly related to both alcohol intake and exercise tolerance levels in both men and women. (ahajournals.org)
- Alcohol intake was not significantly correlated with exercise tolerance. (ahajournals.org)
- Exercise tolerance values were significantly reduced compared to controls. (unboundmedicine.com)
- Purpose: The purpose of this study was to quantify the impact of physical activity associated behaviors and exercise types significantly associated with high stress tolerance (HST) among college students. (ed.gov)
- SPECT/CT imaging provides regional quantification of skeletal muscle perfusion reserve which is significantly associated with exercise tolerance and cardiovascular fitness. (springer.com)
- The magnitude and frequency of peak exercise ST-segment depression reduced significantly in the CSWT+OMT group compared with the OMT+placebo group at the 6-month follow-up (51.4 vs. 90.6%, P =0.001). (ovid.com)
- The authors of a research study report published in the October 2007 issue of 'European Journal of Cardiovascular Prevention and Rehabilitation' reported that exercise tolerance is impaired and and the duration of time young, health men who smoke are able to tolerate exercise is significantly shorter compared to nonsmokers. (livestrong.com)
- 75 years) and women, independently, were significantly less likely to undergo exercise tolerance testing (exercise ECG) and cardiac catheterisation. (ox.ac.uk)
- Exercise tolerance is significantly compromised. (wikipedia.org)
METHODS7
- The results from this study would provide preliminary data, using non-invasive methods, on oxidative capacity in ambulatory SMA patients and disease controls to aid in the design of exercise intervention studies. (clinicaltrials.gov)
- The difference between critical and recovery power ( D CP ), time constant for reconstitution of W´ ( \(\tau_{{W^{\prime}}}\) ), time to limit of tolerance ( T LIM ), and W´ BAL from the integral ( W´ BALint ), differential ( W´ BALdiff ), and locomotor-specific (OG- W´ BAL ) methods were compared. (springer.com)
- Methods: Research design employed was an quantitative, analytical, cross-sectional study of randomly selected college students (N = 936) that completed a stress tolerance questionnaire (STQ) coupled with a physical activity log. (ed.gov)
- METHODS: In a randomized order, all patients performed PLB and control breathing (CB) during constant work-rate exercise in an electrically-braked cycloergometer. (minervamedica.it)
- METHODS: Participants with and without LBP completed testing pre- and post-6 weeks of progressive home exercise intervention. (iospress.com)
- METHODS: We examined the relation of two indices of physical activity-walking pace and leisure activity-to total mortality, CHD, and other cardiovascular diseases in a 25-year follow-up of 6408 male British Civil Servants who underwent an oral glucose tolerance test at study entry. (lshtm.ac.uk)
- This study aimed to evaluate muscle oxidative function during exercise in amyotrophic lateral sclerosis patients (pALS) with non-invasive methods in order to assess if determinants of reduced exercise tolerance might match ALS clinical heterogeneity. (nature.com)
Symptoms11
- This approach appears to be more responsive than other tests, as it allows for placebo-controlled comparisons of symptoms and physiological parameters, including exercise endurance time (ET), at a standardised work rate or power output 5 , 7 . (ersjournals.com)
- Unaddressed, these symptoms often result in depression and social isolation, causing further decline in exercise tolerance and functional performance. (jaoa.org)
- Thus, it is likely that diastolic dysfunction may limit exercise tolerance before resulting in symptoms at rest. (onlinejacc.org)
- The current study aimed to evaluate whether CSWT can improve exercise tolerance and relieve angina symptoms in addition to optimal medical treatment in patients with stable angina. (ovid.com)
- 1 Proposed mechanisms for this positive effect on chemotherapy treatment tolerance include exercise-related amelioration of specific symptoms or toxicities that cause treatment reductions or delays, including neutropenia, fatigue, and neuropathy. (jnccn.org)
- Dyspnoea and decreased exercise tolerance are symptoms of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). (viamedica.pl)
- The amount of exercise to be performed gradually increases over several minutesuntil the patient experiences excessive symptoms (e.g., fatigue, shortness of breath, chest pain, or claudication) or until objective findings of cardiopulmonary malfunction are demonstrated (e.g., arrhythmias, decreases in blood pressure, or ST-segment changes on the electrocardiogram). (thefreedictionary.com)
- Exercise tests are used most often to help diagnose symptoms or signs suggestive of coronary ischemia. (thefreedictionary.com)
- Fatigue and a decreased capacity to exercise are other symptoms that commonly result from heart failure. (medicinenet.com)
- Iron metabolism is disturbed, and administration of iron might improve both symptoms and exercise tolerance. (elsevier.com)
- Conclusions: Intravenous iron loading improved exercise capacity and symptoms in patients with CHF and evidence of abnormal iron metabolism. (elsevier.com)
Dyspnea3
- Exercise endurance, inspiratory capacity (IC) during exercise, IC and expiratory volumes from spirometry, plethysmographic lung volumes, leg discomfort and dyspnea under exercise (Borg scales), and transition dyspnea index were measured on Days 1 and 21 of treatment. (dovepress.com)
- Exercise tolerance and dyspnea in patients with chronic obstructive pulmonary disease]. (semanticscholar.org)
- Frequently seen clinical features includes dyspnea, respiratory distress, recurrent pulmonary infections, and limited exercise tolerance. (wikipedia.org)
Baseline8
- Overall, 28% of the variance in exercise tolerance was explained at baseline, 19% at 14 weeks, and 20% at 9 months. (biomedsearch.com)
- All idiopathic subjects with a baseline and study endpoint measurement of both hemodynamic and exercise endpoints were included. (biomedsearch.com)
- Exercise echocardiograms (Modified Bruce Protocol) and the Minnesota Living With Heart Failure questionnaire were administered at baseline, and after each two-week treatment period, separated by a two-week washout period. (onlinejacc.org)
- The aim of this parallel-group randomised controlled trial was to evaluate the effects of exercise training on pancreatic fat and beta cell function in healthy and prediabetic or type 2 diabetic participants and to test whether the responses were similar regardless of baseline glucose tolerance. (springer.com)
- Two weeks of exercise training improves beta cell function in prediabetic or type 2 diabetic individuals and decreases pancreatic fat regardless of baseline glucose tolerance. (springer.com)
- RESULTS: In 352 men who were identified as having Type 2 diabetes or impaired glucose tolerance (diabetes/IGT) at baseline, 215 had died at follow-up and, in 6056 normoglycaemics, 2550 deaths had occurred. (lshtm.ac.uk)
- Dyspnoea at baseline and after exercise and oxygen saturation (SpO 2 ) during exercise was measured. (viamedica.pl)
- There were no statistical significant differences between the groups for the primary endpoint, change in the bicycle exercise tolerance test , from baseline to 6 months follow-up. (thefreedictionary.com)
Pulmonary function4
- In 50 patients with chronic bronchitis the relation was assessed between exercise tolerance and pulmonary function and psychological factors, including subjective perception of exertion, mood, general psychiatric disturbance, and the attitudes and beliefs held by patients concerning themselves, their illness, and its treatment. (bmj.com)
- While early-stage CKD patients may show changes in pulmonary function and lowered exercise tolerance, the role of the estimated glomerular filtration rate (eGFR) in these patterns remains unknown. (biomedcentral.com)
- The aim of this study was to investigated pulmonary function and exercise tolerance in pre-dialytic CKD patients. (biomedcentral.com)
- Despite their potential relevance in CKD, exercise tolerance and pulmonary function have been little studied in pre-dialytic CKD patients [ 15 ] The aim of this study, therefore, was to evaluate the respiratory function and the exercise tolerance of pre-dialytic CKD patients in stages 3, 4, and 5. (biomedcentral.com)
Glucose19
- In contrast to the negative effects of many adipokines, our study identified transforming growth factor beta 2 (TGF-beta 2) as an adipokine released from adipose tissue (fat) in response to exercise that actually improves glucose tolerance," says Laurie J. Goodyear, PhD, Head of Joslin's Section on Integrative Physiology and Metabolism and study co-author. (medindia.net)
- In response to exercise, an adipokine TGF beta 2 is released from the adipose tissue cells that improve glucose tolerance. (medindia.net)
- Not only did exercise-stimulated TGF-beta 2 improve glucose tolerance, treating obese mice with TGF beta 2 lowered blood lipid levels and improved many other aspects of metabolism. (medindia.net)
- The experiment showed a number of positive metabolic effects in the mice, including improved glucose tolerance and increased fatty acid uptake. (medindia.net)
- Carbohydrate (CHO) also enhances exercise capacity ( 4 ) by maintaining blood glucose and enhancing CHO oxidation ( 3 ). (frontiersin.org)
- Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control. (clinicaltrials.gov)
- Blood glucose concentrations will be sampled every 15 min following an oral glucose tolerance test. (clinicaltrials.gov)
- OBJECTIVE Individuals with impaired glucose tolerance (IGT) have a high risk of developing NIDDM. (diabetesjournals.org)
- Impaired glucose tolerance (IGT) is a transitory state between normoglycemia and frank diabetes. (diabetesjournals.org)
- More intense exercise prescriptions would appear to be needed to improve glucose tolerance and insulin action. (diabetesjournals.org)
- Although higher exercise intensity is a key determinant for improvements in glucose homeostasis, it may produce mechanical and oxidative damage that can result in transitory impairments in insulin action and glucose tolerance. (diabetesjournals.org)
- This transitory condition is known as impaired glucose tolerance (IGT). (diabetesjournals.org)
- Exercise is often prescribed as an initial therapy to control elevations in blood glucose. (diabetesjournals.org)
- However, guidelines that specifically address the use of exercise in controlling blood glucose in individuals with IGT have not been developed. (diabetesjournals.org)
- mean ± SE) with impaired glucose tolerance (IGT) who were randomized to the American Heart Association (AHA) Step 2 diet plus endurance exercise ( n = 30) versus the AHA Step 1 diet plus stretching ( n = 32) for 24 months. (diabetesjournals.org)
- The incremental area under the curve for glucose (incAUCg) was calculated from a 75-g oral glucose tolerance test. (diabetesjournals.org)
- The benefit of lifestyle modifications for reducing the progression to type 2 diabetes in subjects with impaired glucose tolerance (IGT) has been demonstrated in several large randomized studies ( 2 - 4 ). (diabetesjournals.org)
- Prediabetes (impaired fasting glucose and/or impaired glucose tolerance) and type 2 diabetes were defined by ADA criteria. (springer.com)
- AIMS: Given that studies of individuals with Type 2 diabetes or impaired glucose tolerance indicate that physical activity has a normalizing effect on several indices of coronary heart disease (CHD) risk-including body weight, blood pressure, blood lipids, and cardiorespiratory fitness-it is plausible that activity may reduce CHD incidence in this group in the long term. (lshtm.ac.uk)
Coronary4
- An exercise tolerance test (ETT) - also known as an exercise electrocardiogram (ECG) - can help to assess the severity of coronary heart disease. (almondsburysurgery.nhs.uk)
- Exercise tolerance testing (ETT) is one method which is used to determine the presence of significant coronary heart disease. (high-kick.ru)
- Equity in access to exercise tolerance testing, coronary angiography, and coronary artery bypass grafting by age, sex and clinical indications. (ox.ac.uk)
- OBJECTIVES: To assess whether patients with heart disease in a single UK hospital have equitable access to exercise testing, coronary angiography, and coronary artery bypass graft surgery (CABG). (ox.ac.uk)
Test47
- The exercise tolerance test evaluates the ability of your heart and lungs to provide oxygen and remove carbon dioxide from the bloodstream before, during and after you exercise. (nationaljewish.org)
- The exercise for desaturation test evaluates your oxygen needs at rest and during exercise. (nationaljewish.org)
- What is done during the Exercise Test? (nationaljewish.org)
- A technician will explain what you need to do during the exercise test. (nationaljewish.org)
- If you are doing the exercise tolerance test, you will be asked to ride a stationary bicycle. (nationaljewish.org)
- The Exercise Tolerance test often takes 2 hours. (nationaljewish.org)
- The Exercise for Desaturation test often takes 1½ hour. (nationaljewish.org)
- What is an Exercise Tolerance Test? (wregional.com)
- An exercise tolerance test lets the physician see how well your heart functions when it works harder. (wregional.com)
- When the exercise portion of the test is over, your EKG and blood pressure will continue to be monitored for several minutes. (wregional.com)
- Participants will undergo an exercise stress test performed by a clinical exercise physiologist using an electronically-braked recumbent cycle ergometer to determine peak oxygen uptake (VO2 max). (clinicaltrials.gov)
- These recommendations were based on the demonstrations that the improvement in the maximum work rate attained on the ramp-type incremental exercise test, in response to a particular intervention, was relatively small and often close to the limit of the "minimum clinically important difference" 3 . (ersjournals.com)
- In contrast, the change in time to the limit of tolerance ( t LIM ) on a constant-load test, chosen to be a high fraction of the maximum incremental work rate, was shown to be appreciably larger and hence considered to be more discriminatory, to the extent that investigators now often forego the post-intervention maximum incremental test 4 - 6 . (ersjournals.com)
- 8 are, perhaps, even more striking: endurance training resulted in an average increase in the maximum incremental work rate of ∼20%, compared with ∼300% average increase in tolerance to a constant-load test. (ersjournals.com)
- Mice that were able to exercise daily leading up to the cold test had a higher body temperature and lost less weight in their effort to stay warm. (uoguelph.ca)
- The aim of this study is to test our hypothesis that normal exercise tolerance differs according to gender and to identify potential functional cardiac relationships, which could explain those differences. (diva-portal.org)
- An exercise tolerance test was completed upon entry into cardiac rehabilitation, after 14 weeks, and after 9 months. (biomedsearch.com)
- Exercise tolerance test demonstrating dynamic Brugada ECG pattern. (bmj.com)
- The 6-minute stepper test (6MST) is a new, well-tolerated, reproducible exercise test, which can be performed without any spatial constraints. (dovepress.com)
- The aim of this study was to test the hypothesis that use of tiotropium, a new long-acting anticholinergic bronchodilator, would be associated with sustained reduction in lung hyperinflation and, thereby, would improve exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease. (ersjournals.com)
- Participants completed a cycling-graded exercise test, heat acclimation state test, and a time to task failure (TTTF) at 80% peak power output in temperate (TTTFTEMP : 22°C/40% RH) and hot conditions (TTTFHOT : 38°C/20% RH), before and after 10-sessions (60 min of cycling at ~2 W·kg-1) in 45°C/20% RH (ODHA and TDHA) or 22°C/40% RH (ODTEMP or TDTEMP). (unboundmedicine.com)
- Exercise tolerance by six-minute walk test, quadriceps muscle strength by a dynamometer and quality of life by Minnesota Questionnaire. (ahajournals.org)
- Cardiopulmonary exercise testing, lung function tests, and echocardiographic study were performed on both the test and control groups to measure maximal aerobic capacity and cardiac function. (contemporaryobgyn.net)
- The patients and controls (n=10) each for male and female groups were subjected to spirometry using computerised electronic spirometer while exercise tolerance was evaluated by modified Harvard step test. (unboundmedicine.com)
- 2. Each subject performed two types of exercise test breathing three different gas mixtures: air, 35% oxygen in nitrogen and 21% oxygen in helium. (portlandpress.com)
- The aim of the study was to test the hypothesis that angiotensin II (Ang II) blockade would improve exercise tolerance in patients with diastolic dysfunction and a marked increase in systolic blood pressure (SBP) during exercise. (onlinejacc.org)
- The purpose of this dissertation was to test the overarching hypothesis that muscle contraction characteristics (i.e., intensity of contraction, muscle contraction-relaxation duty cycle, etc.) alter oxygen delivery and oxygen utilization, which directly influence the power-duration relationship and fatigue development, and therefore, exercise tolerance. (k-state.edu)
- All participants underwent spirometric and manovacuometric tests, a cardiopulmonary exercise test (CPET), a 6-minute walk test (6MWT), and laboratory tests. (biomedcentral.com)
- Inspiratory capacity, dynamic hyperinflation, breathlessness, and exercise performance during the 6-minute-walk test in chronic obstructive pulmonary disease. (semanticscholar.org)
- Our study results showed that exercise tolerance test has high positive predictive value. (thefreedictionary.com)
- Submaximal Clinical Exercise Tolerance Test - Case Example 1 (Jerry Mode: Schwinn AirDyne[TM] Cycle Ergometer Resting HR: 68 AAMHR: 162 * Resting BP: 136/76 85%AAMHR: 138 * Min Workload HR BP RPE 0-2 20 W 94 1 2-4 40 W 107 138/78 2 4-6 60 W 117 4 6-8 80 W 136 152/80 7 Test Interpretation: Moderate intensity arm/leg ergometry tolerated well. (thefreedictionary.com)
- An exercise tolerance test is often used as part of a screening medical for certain jobs with safety critical responsibilities such as public service drivers, ie taxi, bus and train drivers, particularly after a heart attack or chest pain. (dorsetheartclinic.co.uk)
- Exercise tolerance was assessed by an incremental exercise test on cycle ergometer measuring peak O 2 uptake ( \(\dot{{\rm{V}}}\) O 2peak ), vastus lateralis oxidative function by near infrared spectroscopy (NIRS) and breathing pattern ( \(\dot{{\rm{V}}}\) E peak ). (nature.com)
- You should also avoid strenuous exercise for several hours before the test and refrain from smoking for 24 hours. (ruzicka.co.uk)
- If you feel you cannot continue, the test will be stopped, but it is important that you do as much exercise as possible for the results to be meaningful. (ruzicka.co.uk)
- Once the exercise section of the test has finished, you will be able to lie down, and your heart will be monitored with an ECG and a blood pressure machine until it returns to its resting rate. (ruzicka.co.uk)
- Dr Ruzicka will review and analyse your exercise test to see if the ECG tracings show any arrhythmias or signs of ischaemic heart disease. (ruzicka.co.uk)
- An exercise tolerance test (ETT) records the electrical activity of your heart whilst you exercise. (almondsburysurgery.nhs.uk)
- Most people manage to do the exercise tolerance test (ETT). (almondsburysurgery.nhs.uk)
- Are there any risks when doing an exercise tolerance test? (almondsburysurgery.nhs.uk)
- An Exercise Tolerance Test as described above, but in addition, the patient breathes through a special mouthpiece to determine how much and how effectively the body uses oxygen. (rochester.edu)
- A normal exercise test may reassure many patients but it does not exclude a diagnosis of CAD. (high-kick.ru)
- A cardiac stress test is a recording of the heart's activity during exercise. (epnet.com)
- The exercise portion of the test generally takes less than 15 minutes. (epnet.com)
- Background: Although many studies of heart failure therapies test improvements of patient condition in terms of mean changes of quality of life (QoL) or exercise tolerance (ET) measures, it is of increasing interest to quantify the proportion of patients that "respond" to therapy and understand factors predicting response. (elsevier.com)
- The three most common reasons people give for being unable to tolerate a normal amount of exercise or physical activity are: breathlessness - commonly seen in people with lung diseases, heart disease, and obesity fatigue - When it appears early in an exercise test, it is usually due to deconditioning (either through a sedentary lifestyle or while convalescing from a long illness), but it can indicate heart, lung, or neuromuscular diseases. (wikipedia.org)
- Common tests include stair climbing, walking for six minutes, a shuttle-walk test, a cardiac stress test, and the cardiopulmonary exercise test (CPET). (wikipedia.org)
Maximal7
- Spirometry, plethysmographic lung volumes, cycle exercise endurance and exertional dyspnoea intensity at 75% of each patient's maximal work capacity were compared. (ersjournals.com)
- 2. The effects of 2 weeks on two levels of salt intake (50 and 150 mmol/day) on the ability to exercise (60% of maximal oxygen uptake) in a hot environment (35°C) were studied in eight healthy normotensive subjects. (clinsci.org)
- Women with Turner syndrome (TS) have lower maximal aerobic capacity and lower exercise tolerance than controls, according to a study published in the April 1 issue of The American Journal of Cardiology. (contemporaryobgyn.net)
- The patients with TS had a lower maximal aerobic capacity and exercise tolerance than did the controls. (contemporaryobgyn.net)
- Pre-dialytic CKD patients showed lower maximal and submaximal exercise tolerances than healthy individuals. (biomedcentral.com)
- In healthy persons, the increase in cardiac output during maximal upright exercise typically is four- to sixfold, which is accomplished by a two- to fourfold increase in heart rate and a 20 to 50 percent increase in stroke volume. (aafp.org)
- Patients may have less than 50 percent of the maximal cardiac output of a healthy person at peak exercise. (aafp.org)
Peak exercise5
- During control, patients were able to exercise for 11.3 ± 2.5 (mean ± SD) min, with a peak exercise SBP of 226 ± 24 mm Hg. (onlinejacc.org)
- With placebo, there was no improvement in exercise duration (11.0 ± 2.0 min) or peak exercise SBP (217 ± 26 mm Hg). (onlinejacc.org)
- Metabolic equivalents (METs) at peak exercise and heart rate recovery (HRR) after exercise were recorded. (springer.com)
- Dynamic hyperinflation, oxygen saturation and breathing pattern were recorded at rest, in isotime and in peak exercise. (minervamedica.it)
- Results from Dr. Harris and colleague Dr. McKie's studies have indicated that during peak exercise the Cystic Fibrosis subjects consumed 14% less oxygen while their expelled air had higher oxygen levels, "indicating that their muscles were not as efficient at using it. (powerbreathe.com)
Fatigue12
- Using a double-blind crossover design, ET and SED ( n = 12 each group) completed four exercise trials consisting of 30 min cycling at standardized matched work rates 10% below lactate threshold (MOD-EX) followed by a time to fatigue (TTF) ride at individually prescribed intensity of 5% above lactate threshold. (frontiersin.org)
- Athletes ingest caffeine and carbohydrate to improve performance and delay fatigue during exercise ( 1 - 4 ). (frontiersin.org)
- Whether a generalized fatigue prevents the undertaking of exercise or the acute discomfort/fatigue that directly results from exercise is the more relevant barrier remains unclear ( 6 ). (frontiersin.org)
- The final investigation (Chapter 4) utilized periods of blood flow occlusion during and post-exercise to reveal greater magnitudes of peripheral and central fatigue development during blood flow occlusion exercise compared to control blood flow exercise. (k-state.edu)
- Rather, W' may be determined by the magnitude of fatigue accrued during exercise, which is dependent upon oxygen delivery and oxygen utilization. (k-state.edu)
- Fatigue of the respiratory muscles during intense exercise might compromise leg blood flow, thereby constraining oxygen uptake ( O2) and limiting exercise tolerance. (powerbreathe.com)
- This study tested the hypothesis that inspiratory muscle training (IMT) would reduce inspiratory muscle fatigue, speed O2 kinetics and enhance exercise tolerance. (powerbreathe.com)
- Caffeic acid is used in supplements for boosting athletic performance and has shown promise in reducing the fatigue associated with exercise, however research is limited. (nutrientjournal.com)
- People who have fibromyalgia and chronic fatigue syndrome usually have a difficult time exercising because they often get exhausted quickly by even a moderate amount of exercise. (livestrong.com)
- Malic acid has been found to increase tolerance to exercise in people who have fibromyalgia and chronic fatigue syndrome, which allows them to exercise for longer time periods or at higher intensities. (livestrong.com)
- It also includes experiences of unusually severe post-exercise pain, fatigue, nausea, vomiting or other negative effects. (wikipedia.org)
- or exercise might result in severe headache, nausea, dizziness, occasional muscle cramps or extreme fatigue, which would make it intolerable. (wikipedia.org)
Uptake7
- No differences in mean oxygen uptake, heart rate or rectal temperature during exercise were observed between the two salt intakes. (clinsci.org)
- In the study 'Inspiratory muscle training enhances pulmonary O2 uptake kinetics and high-intensity exercise tolerance in humans' the results indicated that "the enhanced exercise tolerance observed after IMT might be related, at least in part, to improved Vo(2) dynamics, presumably as a consequence of increased blood flow to the exercising limbs. (powerbreathe.com)
- and (ii) whether the accelerated oxygen uptake kinetics following priming exercise can improve exercise tolerance. (exeter.ac.uk)
- During the tests oxygen uptake, muscle oxygenation, muscle electrical activity and exercise tolerance were measured. (exeter.ac.uk)
- A correlation was present between the change in tissue oxygenation index during bout 2 and the change in the phase II (r = -0.72, likely negative) and slow component (r = 0.72, likely positive) oxygen uptake amplitudes following priming exercise, but not for muscle activity. (exeter.ac.uk)
- The altered phase II and slow component oxygen uptake amplitudes in boys following priming exercise are linked to an improved localised matching of muscle oxygen delivery to oxygen uptake and not muscle electrical activity. (exeter.ac.uk)
- Despite more rapid oxygen uptake kinetics following priming exercise, exercise tolerance was not enhanced. (exeter.ac.uk)
Physiological6
- The factors that limit exercise capacity may be different in patients with different disease entities (i.e., chronic obstructive, restrictive or pulmonary vascular lung disease) or disease severity and ultimately depend on the degree of malfunction or miss coordination between the different physiological systems (i.e., respiratory, cardiovascular and peripheral muscles). (nih.gov)
- Exercise tolerance or physiological fitness appears to be important in quantifying the relation between alcohol intake and blood pressure and should be considered in describing this relation. (ahajournals.org)
- In view of the abnormal physiological adaptations to exercise in patients with CF with advanced lung disease (PFS greater than 12), they should engage in exercise training programs and strenuous physical activity with caution and only after their cardiorespiratory reserves and adjustments to exercise have been objectively evaluated. (nih.gov)
- Without knowledge of these features, any absolute or per cent increase in tolerance time to a single constant-load exercise bout must be interpreted with caution regarding the physiological benefit(s) that have accrued from the intervention. (ersjournals.com)
- The physiological mechanisms determining the tolerable duration of exercise dictate human physical accomplishments across all spectrums of life. (k-state.edu)
- The novel findings of the investigations presented in this dissertation highlight important physiological mechanisms that determine exercise tolerance and demonstrate the need for interventions that improve oxygen delivery and oxygen utilization in specific populations, such as those with chronic heart failure or chronic obstructive pulmonary disease, to improve exercise tolerance. (k-state.edu)
CONCLUSIONS5
- CONCLUSIONS Diet and/or exercise interventions led to a significant decrease in the incidence of diabetes over a 6-year period among those with IGT. (diabetesjournals.org)
- CONCLUSIONS: PVRI should not be used as a surrogate marker to predict changes in exercise capacity. (biomedsearch.com)
- Conclusions: This study demonstrated the positive protective impact of physical activity behaviors and exercise on stress tolerance among college students. (ed.gov)
- Conclusions Pharmacotherapy of heart failure with preserved ejection fraction demonstrates a quantifiable improvement in exercise tolerance but not mortality. (onlinejacc.org)
- CONCLUSIONS: Individuals with LBP meeting clinical prediction rules for stabilization-based exercise demonstrated increased standing tolerance and sagittal plane muscle sequencing following a 6-week intervention. (iospress.com)
Skeletal muscle5
- The objective of this study was to investigate the effect of a fast skeletal troponin activator, CK-2127107 (2-aminoalkyl-5- N -heteroarylpyrimidine), on skeletal muscle function and exercise performance in rats exhibiting heart failure-mediated skeletal myopathy. (aspetjournals.org)
- Although exercise is often prescribed for the management of cardiovascular diseases, a non-invasive imaging approach that quantifies skeletal muscle physiology and correlates with patients' functional capacity and cardiovascular fitness has been absent. (springer.com)
- Future application of SPECT/CT may elucidate the underlying skeletal muscle adapations to exercise therapy in patients with cardiovascular diseases. (springer.com)
- Inefficient skeletal muscle O 2 function, when flanking the impaired motor units recruitment, is a major determinant of pALS clinical heterogeneity and working capacity exercise tolerance. (nature.com)
- In pALS this phenomenon has not been fully characterized in term of the underlying governing dynamics of oxidative metabolism, and specifically by assessing skeletal muscle oxidative function during exercise. (nature.com)
Intensity15
- Oral taurine improves critical power and severe-intensity exercise tolerance. (nih.gov)
- Magnitude of spinal muscle damage is not statistically associated with exercise-induced low back pain intensity. (duke.edu)
- CAF also has neuromodulatory effects in the brain enhancing task persistence and determination likely through adenosine inhibition ( 10 , 15 ), thus, allowing individuals to perform more work at the same effort or perceive the same exercise intensity as more tolerable and/or less painful ( 1 , 2 , 16 , 17 ). (frontiersin.org)
- Recent physical activity guidelines from the Centers for Disease Control and Prevention and the American College of Sports Medicine have suggested that intermittent moderate-intensity exercise is beneficial and can improve the health status of these individuals. (diabetesjournals.org)
- Therefore, the optimal exercise intensity for an individual with IGT appears to lie between these two extremes. (diabetesjournals.org)
- 2 Specifically, they have suggested that every American should accumulate 30 min of moderate-intensity exercise on most, if not all, days of the week. (diabetesjournals.org)
- Walking briskly (3-4 miles per hour), gardening, and general home-care activities have been classified as moderate-intensity exercise. (diabetesjournals.org)
- The current activity guidelines are based primarily on epidemiological data that suggest that those who perform 30 min of moderate-intensity exercise per day have lower morbidity and mortality rates than those who are habitually inactive. (diabetesjournals.org)
- Although a wealth of epidemiological data support the current guidelines, little clinical evidence exists that would suggest that intermittent moderate-intensity exercise by itself would be beneficial in improving glycemic status. (diabetesjournals.org)
- Individuals differ in the intensity of exercise they prefer and the intensity they can tolerate. (humankinetics.com)
- The purpose of this project was to develop a measure of individual differences in the preference for and tolerance of exercise intensity. (humankinetics.com)
- The Preference for and Tolerance of the Intensity of Exercise Questionnaire (PRETIE-Q) is a 16-item, 2-factor measure that exhibits acceptable psychometric properties and can be used in research aimed at understanding individual differences in responses to exercise and thus the psychological processes involved in the public health problem of exercise dropout. (humankinetics.com)
- Furthermore, improving the (nutritional) conditions under which exercise promotes muscle protein synthesis is not only important for athletes, but also in clinical conditions requiring enhanced anabolic response in patients who are unable to perform high-intensity exercise. (frontiersin.org)
- Intensity of exercise is measured in metabolic equivalents (METs) where 1 MET is the amount of energy expended at rest or 3.5 ml oxygen per kilogram per minute. (high-kick.ru)
- Seven boys that were aged 11.3 ± 1.6 years completed either a single bout (bout 1) or repeated bouts with 6 min of recovery (bout 2) of very heavy-intensity cycling exercise. (exeter.ac.uk)
Rehabilitation4
- Essential Amino Acids and Exercise Tolerance in Elderly Muscle-Depleted Subjects with Chronic Diseases: A Rehabilitation without Rehabilitation? (hindawi.com)
- The enduring impact of social factors on exercise tolerance in men attending cardiac rehabilitation. (biomedsearch.com)
- RESULTS: Sociodemographic factors and social support reported upon entry into the cardiac rehabilitation program were related to initial and post-cardiac rehabilitation exercise tolerance, after controlling for admitting diagnoses, medical history, smoking, and perceived severity of illness. (biomedsearch.com)
- The reduced exercise tolerance in pALS ( i . e ., the capacity to maintain workloads ranging from habitual activities to rehabilitation exercises) has been associated with mitochondrial dysfunction, both as a direct pathogenic mechanism and as a factor contributing to the exercise limitation 5 , 6 . (nature.com)
Inspiratory2
- Resultant increases in inspiratory capacity permitted greater expansion of tidal volume and contributed to improvements in both exertional dyspnoea and exercise endurance. (ersjournals.com)
- Effect of inspiratory pressure support on exercise tolerance and breathlessness in patients with severe stable chronic obstructive pulmonary disease. (bmj.com)
6MWT3
- 6MWT is an objective evaluation of functional exercise capacity, measures the maximum distance a person can walk in six minutes over a 25-meter linear course. (clinicaltrials.gov)
- The haemoglobin concentration did not correlate with 6MWT, dyspnoea during 6MWT, or exercise oxygenation and blood desaturation during exercise. (viamedica.pl)
- Researchers assessed each patient's response through spirometry tests , and compared the changes to those seen in exercise capacity tests, including the 6MWT, and other lung function tests. (cysticfibrosisnewstoday.com)
Physiology1
- She owns Moxie Personal Training and is pursuing a Bachelor of Science in exercise physiology at Portland State University. (livestrong.com)
Aerobic5
- Aerobic exercise can benefit your health in many ways. (medindia.net)
- This study compared chemotherapy treatment tolerance and survival among women receiving adjuvant chemotherapy for early-stage breast cancer who participated in a single-arm trial of supervised aerobic and resistance exercise programming versus a historical cohort that did not receive structured exercise programming. (jnccn.org)
- Furthermore, although C a O 2 was reduced by approximately 50% at the highest P CO 2 , there was no effect of hypercapnia on the eels' tolerance of hypoxia, aerobic metabolic scope or sustained swimming performance. (biologists.org)
- The aim of this study was to evaluate the impact of aerobic and resistance exercise training modalities on arterial remodeling in patients with chronic heart failure. (ahajournals.org)
- 3 , 6 , - , 9 However, few previous studies have directly compared the effects of resistance and aerobic exercise training in CHF patients. (ahajournals.org)
Evaluate5
- To evaluate exercise tolerance. (clinicaltrials.gov)
- OBJECTIVES: This study was designed to assess the prevalence of provoked exercise desaturation (PED) in patients with patent foramen ovale (PFO) referred for cardiovascular evaluation and to evaluate the impact of PFO closure. (duke.edu)
- Therefore, this study was designed to evaluate the effects of tiotropium on exercise endurance and exertional dyspnoea, and to examine possible mechanisms for this overall functional improvement. (ersjournals.com)
- The aim of this study is to evaluate the benefits on perceived quality of life (QOL) and physical fitness of a home-based physical exercise program compared to usual care, for patients with stabilised, generalised auto-immune MG. (springermedizin.de)
- Exercise testing is used to evaluate the heart and lung function of children. (rochester.edu)
Cardiac output during e2
- The ability to increase the cardiac output during exercise without an abnormal elevation in left atrial pressure depends on the capacity of the left ventricle to enhance its diastolic filling (4) . (onlinejacc.org)
- Although cardiovascular disease limits the increase of cardiac output during exercise, this response also is affected by age, gender, and conditioning status. (aafp.org)
Chronic heart f6
- Regional blood flow in chronic heart failure: the reason for the lack of correlation between patients' exercise tolerance and cardiac output? (bmj.com)
- Right heart dysfunction [ncbi.nlm.nih.gov] Numerous mechanisms unrelated to hemodynamic dysfunction may underlie impaired exercise tolerance in patients with chronic heart failure. (symptoma.com)
- Exercise training is an important adjunct to medical therapy in chronic heart failure, but the extent to which exercise impacts on conduit artery remodeling is unknown. (ahajournals.org)
- Our findings suggest that exercise has a systemic impact on remodeling of conduit arteries in humans and that resistance exercise training may be advantageous in subjects with chronic heart failure in this regard. (ahajournals.org)
- Exercise training in chronic heart failure (CHF) patients is associated with improved prognosis, 1 , 2 functional capacity, 2 , 3 and quality of life. (ahajournals.org)
- Effect of Intravenous Iron Sucrose on Exercise Tolerance in Anemic and Nonanemic Patients With Symptomatic Chronic Heart Failure and Iron Deficiency. (elsevier.com)
Angina6
- The effect of oral and intravenous tolamolol on exercise tolerance was assessed in 11 patients with angina pectoris. (bmj.com)
- Effects of Molsidomine on global and regional left ventricular function at rest and during exercise in patients with angina pectoris. (springer.com)
- Haemodynamic and electrocardiographic effects of frusemide during supine exercise in patients with angina pectoris. (springer.com)
- Exercise testing is potentially hazardous to patients with unstable angina pectoris, myocardial infarction within the last 48 hours, uncontrolled heart failure, aortic dissection, pulmonary embolism, ataxia or severe arthritic disease. (thefreedictionary.com)
- Most patients with suspected angina were traditionally referred for exercise ECG testing. (high-kick.ru)
- [ 5 ] The 2010 National Institute for Health and Care Excellence (NICE) guidance for patients presenting with chest pain recommends that exercise ECG should not be used to diagnose or exclude stable angina for people without known CAD. (high-kick.ru)
Hyperinflation2
- In conclusion, the use of tiotropium was associated with sustained reductions of lung hyperinflation at rest and during exercise. (ersjournals.com)
- According to the current authors' hypothesis, use of once-daily tiotropium would be associated with improved tidal expiratory flow rates (and lung emptying), reduced resting and exercise lung hyperinflation, and consequent alleviation of exertional dyspnoea. (ersjournals.com)
Cystic fibrosis2
- Exercise tolerance and cardiorespiratory adjustments at peak work capacity (PWC) were determined in 20 patients with cystic fibrosis (CF) during progressive cycle ergometry. (nih.gov)
- We recently came across an article that reported on how patients with Cystic Fibrosis (CF) have less exercise capacity than their peers, even though their lungs may be relatively healthy. (powerbreathe.com)
Capacity12
- ILD and PVD are included because there is sufficient experimental evidence for the factors that limit exercise capacity and because these disorders are representative of restrictive and pulmonary vascular disorders, respectively. (nih.gov)
- The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 patients with severe chronic bronchitis and emphysema (mean forced expiratory volume in one second 0.56 1, mean forced vital capacity 1.54 1). (bmj.com)
- This proposal will focus on (1) estimating oxidative capacity of specific muscle groups during exercise using near infrared spectroscopy and (2) describing body composition to better understand exercise capacity and mitochondrial function in ambulatory spinal muscular atrophy (SMA) patients and disease controls. (clinicaltrials.gov)
- Thus, normal exercise capacity as determined by pVO(2) is related to the indexed stroke volume in males and left atrial pressure in females. (diva-portal.org)
- BACKGROUND: Clinical trials for adults with pulmonary arterial hypertension use exercise capacity, as measured by walking distance, as the primary endpoint to measure symptomatic improvement. (biomedsearch.com)
- RESULTS: There is a weak correlation between changes in PVRI and exercise capacity. (biomedsearch.com)
- The exercise capacity, ventilation and heart rate were recorded. (portlandpress.com)
- 3. (a) Effort tolerance at a constant load (70% capacity breathing air) was greater when the inspired gas mixture was 35% oxygen in nitrogen than when air or 21% oxygen in helium was breathed. (portlandpress.com)
- Objectives We sought to determine whether pharmacologic interventions changed exercise capacity, diastolic function, and mortality in a meta-analysis of trials in heart failure with preserved ejection fraction. (onlinejacc.org)
- A correlation between resting ventricular function and exercise capacity is expected, but data indicate that the relationship is weak. (aafp.org)
- In patients with heart failure, blood flow to muscles does not increase normally during exercise because of reduced cardiac output and impaired peripheral vasodilatory capacity. (aafp.org)
- Exercise tolerance depends on the capacity of the pulmonary system to deliver oxygen to the working muscle and the capacity of the vasculature to redistribute cardiac output to the muscle during exercise. (aafp.org)
Mechanisms3
- Knuth and Wright sought to distinguish the relative contribution of shivering (muscle) and non-shivering (fat) mechanisms in keeping mice warm - and whether exercise could improve the mouse's tolerance. (uoguelph.ca)
- However, to the researchers' surprise, "non-shivering" mechanisms could not explain the cold-protection conferred by exercise in these mice. (uoguelph.ca)
- Improvements in exercise endurance increased over time, suggesting that mechanisms beyond improved lung function may be involved in enhanced exercise tolerance. (dovepress.com)
Cardiovascular4
- The purpose of this study was to determine whether diet and exercise interventions in those with IGT may delay the development of NIDDM, i.e., reduce the incidence of NIDDM, and thereby reduce the overall incidence of diabetic complications, such as cardiovascular, renal, and retinal disease, and the excess mortality attributable to these complications. (diabetesjournals.org)
- A consequence of most cardiovascular diseases is exercise limitation. (springer.com)
- la actividad física a menudo se prescribe como parte del tratamiento de enfermedades cardiovasculares, sin embargo, en la actualidad no existe un enfoque de evaluación no invasiva que cuantifique la fisiología del músculo esquelético y se correlacione con la capacidad funcional y el estado cardiovascular de los pacientes. (springer.com)
- When used in the evaluation of patients with cardiovascular disease, exercise testing is often combined with echocardiography or nuclear imaging of the heart to improve the predictive value, sensitivity, and specificity of the assessment. (thefreedictionary.com)
Arterial7
- If arterial blood gas samples will be taken while you exercise a catheter will be placed in an artery in your arm. (nationaljewish.org)
- The results indicate that whenever pulmonary disease in CF is advanced, there are decreases in exercise tolerance and cardiorespiratory reserves, exercise-induced ventilation-perfusion abnormalities, arterial desaturation, and alveolar hypoventilation. (nih.gov)
- Is pulmonary vascular resistance index predictive of exercise tolerance in adult patients with idiopathic pulmonary arterial hypertension. (biomedsearch.com)
- Systolic arterial pressure normally increases during exercise. (onlinejacc.org)
- In elderly and hypertensive subjects the increase in systolic arterial pressure during exercise is frequently exaggerated (6-8) . (onlinejacc.org)
- Wall thickness and wall:lumen ratio have been used in peripheral conduit arteries to reflect arterial remodeling, 11 , - , 13 a process that may depend on exercise-mediated changes in systemic hemodynamics and arterial shear stress. (ahajournals.org)
- 14 , - , 18 We recently reported important differences in the impact of different exercise modalities on systemic changes in shear stress during bouts of exercise, 19 a finding which raises the possibility that distinct forms of exercise may induce differential changes in arterial size and wall thickness in humans. (ahajournals.org)
Duration1
- The curvilinear relationship between athletic performance and time was originally described by Hill ( 1925 ), where constant power output maintained to the limit of tolerance ( T LIM ) declined as a function of exercise duration. (springer.com)
Desaturation2
- What is Exercise for Desaturation testing? (nationaljewish.org)
- Provoked exercise desaturation in patent foramen ovale and impact of percutaneous closure. (duke.edu)
Improve7
- Our purpose was to determine if these ergogenic aids are also effective to improve exercise tolerance in age-matched sedentary (SED) adults. (frontiersin.org)
- Recently, the American College of Sports Medicine (ACSM), the Centers for Disease Control and Prevention (CDC), and the Surgeon General (SG) have issued statements regarding the recommended quantity and quality of exercise required to improve health status. (diabetesjournals.org)
- 4. It is concluded that a reduction in the density of the inspired gas does not improve effort tolerance in patients with COB. (portlandpress.com)
- Available preliminary evidence is conflicting on whether exercise can positively influence antineoplastic treatment tolerance and in turn improve survival. (jnccn.org)
- KE has recently been shown to improve exercise performance, but whether it can also promote post-exercise muscle protein or glycogen synthesis is unknown. (frontiersin.org)
- A single bout of exercise can acutely improve insulin sensitivity, but this effect dissipates over several days ( 12 - 15 ). (diabetesjournals.org)
- Longer-term exercise interventions revealed little effect to improve insulin sensitivity if changes in weight were prevented ( 16 ) or if changes in weight attained during increased physical activity are matched to those attained by restriction of calorie intake ( 17 ). (diabetesjournals.org)
Improvements3
- Dynamic IC at exercise isotime and trough FEV 1 showed significant and clinically relevant improvements from Day 1 of treatment that were maintained throughout the study. (dovepress.com)
- Once- and twice-daily heat acclimation conferred similar magnitudes of heat adaptation and exercise tolerance improvements, without differentially altering immune function, thus nonconsecutive TDHA provides an effective, logistically flexible method of HA, benefitting individuals preparing for exercise-heat stress. (unboundmedicine.com)
- Results showed that treatment with Orkambi led to significant improvements in patient's exercise tolerance as seen at 4 weeks. (cysticfibrosisnewstoday.com)
Exertion2
- Subjective perception of exertion was most closely correlated with exercise tolerance. (bmj.com)
- Exercise tolerance testing is commonly used to determine the cause of chest pain and dyspnoea on exertion. (hje.org.uk)
Metabolic6
- Two years ago, the international research team first demonstrated that adipose tissue offers beneficial metabolic effects in response to exercise. (medindia.net)
- This reversed the negative metabolic effects of the high fat diet, similar to what happens with exercise. (medindia.net)
- Our results are important because it's really the first demonstration of an exercise-released adipokine that can have beneficial metabolic effects on the body," says Goodyear. (medindia.net)
- This research really revolutionizes the way we think about exercise, and the many metabolic effects of exercise. (medindia.net)
- SED and ET only differed in metabolic oxidation rates during exercise (higher overall fat oxidation with ET compared to SED). (frontiersin.org)
- Ergoreceptors, which mediate circulatory adaptations in the early stages of exercise, are stimulated by metabolic acidosis and are partially responsible for sympathetic vasoconstriction and an increase in heart rate. (aafp.org)
Myocardial infarction2
- They also are frequently used after patients have suffered a myocardial infarction or an exercise-induced arrhythmia. (thefreedictionary.com)
- The NICE guidance also states that, for people with confirmed CAD (eg, previous myocardial infarction, revascularisation, previous angiography), non-invasive functional testing should be offered when there is uncertainty about whether chest pain is caused by myocardial ischaemia, and that exercise ECG may be used instead of functional imaging. (high-kick.ru)
Physical8
- Aerobics is a physical exercise that includes activities like dance, cycling, running, stretching and many more. (medindia.net)
- Statistical differences by type of physical activity and stress tolerance were determined by Chi-Square and Odds Ratio (95%CI). (ed.gov)
- Research exploring the effects of physical exercise in auto-immune myasthenia gravis (MG) is scarce. (springermedizin.de)
- It is hypothesised that exercise could have positive physical, psychological as well as immunomodulatory effects and may be a beneficial addition to current pharmacological management of this chronic disease. (springermedizin.de)
- The experimental group will undertake a 40-min home-based physical exercise program using a rowing machine, three times a week for three months, as an add-on to usual care. (springermedizin.de)
- This is the largest randomised controlled trial to date evaluating the benefits and tolerance of physical exercise in this patient population. (springermedizin.de)
- Anecdotal evidence from patients with MG suggests that those who participate in regular physical exercise feel better. (biomedcentral.com)
- Exercise in this context means physical activity, not specifically exercise in a fitness program. (wikipedia.org)
Increases3
- During the increased ventilation of exercise in flow-limited patients, EELV acutely increases above an already high resting value. (ersjournals.com)
- FES improves MSNA and vasoconstriction and increases exercise tolerance, muscle strength and quality of life in hospitalised HF patients. (ahajournals.org)
- In patients with Doppler evidence of diastolic dysfunction at rest and a hypertensive response to exercise, Ang II receptor blockade blunts the hypertensive response to exercise, increases exercise tolerance and improves quality of life. (onlinejacc.org)
Individuals4
- Specifically, older individuals had poorer exercise tolerance, whereas those with more income had better exercise tolerance. (biomedsearch.com)
- BACKGROUND: Healthy individuals who develop low back pain (LBP) during standing (standing intolerant) respond favorably to stabilization-based exercise interventions. (iospress.com)
- People with clinical LBP meeting clinical prediction rules for stabilization-based exercise share characteristics with standing into lerant individuals. (iospress.com)
- OBJECTIVE: To investigate the impact of stabilization-based exercise on standing tolerance, muscle activation and clinical measures in individuals with LBP meeting clinical prediction rules for stabilization-based exercise. (iospress.com)
Abnormalities1
- It is also used to detect whether rhythm abnormalities can be brought on by exercise. (almondsburysurgery.nhs.uk)
Diastolic3
- The relations of systolic and diastolic blood pressures to alcohol intake and exercise tolerance levels in 15,612 men and 3,855 women were investigated. (ahajournals.org)
- Diastolic dysfunction may be exacerbated during exercise, especially if there is a marked increase in SBP. (onlinejacc.org)
- Angiotensin II may contribute to the hypertensive response to exercise and impair diastolic performance. (onlinejacc.org)
Improvement6
- However, the extremely large variability of the improvement in this particular index of tolerance undermines the ability to make general inferences for the underlying functional improvement. (ersjournals.com)
- The improvement in health status is likely to be multifactorial, but enhanced symptom control and increased exercise capability are potentially important factors. (ersjournals.com)
- NVA237 50 µg once daily produced immediate and significant improvement in exercise tolerance from Day 1. (dovepress.com)
- 2 , 5 In addition, exploratory long-term follow-up of 2 large RCTs showed that exercise was associated with a (non-statistically significant) 32% to 34% improvement in DFS. (jnccn.org)
- In conclusion, exercise combined with weight loss enhances postabsorptive fat oxidation, which appears to be a key aspect of the improvement in insulin sensitivity in obesity. (diabetesjournals.org)
- Improvement in exercise tolerance is an important outcome to consider in those with more severe airways disease," the researchers said. (cysticfibrosisnewstoday.com)
Strenuous1
- I only get breathless with strenuous exercise. (bronchiectasis.com.au)
Results4
- Exercise to get healthy - that way, you'll last longer at it and get better results. (medindia.net)
- 6. On the basis of these results it is concluded that moderate salt restriction does not impair the ability to exercise in a hot environment. (clinsci.org)
- Results The mean exercise time improved in both study arms - CSWT and placebo treatment - at the 3- and 6-month follow-up, without a significant difference between groups. (ovid.com)
- Our results indicate that adding KE to a standard post-exercise recovery beverage enhances the post-exercise activation of mTORC1 but does not affect muscle glycogen resynthesis in young healthy volunteers. (frontiersin.org)