The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
A regimen or plan of physical activities designed and prescribed for specific therapeutic goals. Its purpose is to restore normal musculoskeletal function or to reduce pain caused by diseases or injuries.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
Difficult or labored breathing.
The time span between the beginning of physical activity by an individual and the termination because of exhaustion.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
Therapeutic exercises aimed to deepen inspiration or expiration or even to alter the rate and rhythm of respiration.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.
The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.
A phenoxypropanolamine derivative that is a selective beta-1-adrenergic agonist.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
A test to determine the ability of an individual to maintain HOMEOSTASIS of BLOOD GLUCOSE. It includes measuring blood glucose levels in a fasting state, and at prescribed intervals before and after oral glucose intake (75 or 100 g) or intravenous infusion (0.5 g/kg).
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
The oxygen consumption level above which aerobic energy production is supplemented by anaerobic mechanisms during exercise, resulting in a sustained increase in lactate concentration and metabolic acidosis. The anaerobic threshold is affected by factors that modify oxygen delivery to the tissues; it is low in patients with heart disease. Methods of measurement include direct measure of lactate concentration, direct measurement of bicarbonate concentration, and gas exchange measurements.
These include the muscles of the DIAPHRAGM and the INTERCOSTAL MUSCLES.
Elements of limited time intervals, contributing to particular results or situations.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
A technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure. It may be achieved by intra-aortic balloon, or by implanting a special pumping device in the chest, or externally by applying a negative pressure to the lower extremities during cardiac systole.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.
Freedom from activity.
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
The maximum volume of air that can be inspired after reaching the end of a normal, quiet expiration. It is the sum of the TIDAL VOLUME and the INSPIRATORY RESERVE VOLUME. Common abbreviation is IC.
Examinations used to diagnose and treat heart conditions.
The amount of force generated by MUSCLE CONTRACTION. Muscle strength can be measured during isometric, isotonic, or isokinetic contraction, either manually or using a device such as a MUSCLE STRENGTH DYNAMOMETER.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
An induced state of non-reactivity to grafted tissue from a donor organism that would ordinarily trigger a cell-mediated or humoral immune response.
The volume of air that is exhaled by a maximal expiration following a maximal inspiration.
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Measurement of volume of air inhaled or exhaled by the lung.
A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.
Inhalation of oxygen aimed at restoring toward normal any pathophysiologic alterations of gas exchange in the cardiopulmonary system, as by the use of a respirator, nasal catheter, tent, chamber, or mask. (From Dorland, 27th ed & Stedman, 25th ed)
A clinical syndrome characterized by palpitation, SHORTNESS OF BREATH, labored breathing, subjective complaints of effort and discomfort, all following slight PHYSICAL EXERTION. Other symptoms may be DIZZINESS, tremulousness, SWEATING, and INSOMNIA. Neurocirculatory asthenia is most typically seen as a form of anxiety disorder.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.
A congenital heart defect characterized by downward or apical displacement of the TRICUSPID VALVE, usually with the septal and posterior leaflets being attached to the wall of the RIGHT VENTRICLE. It is characterized by a huge RIGHT ATRIUM and a small and less effective right ventricle.
AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.
The inferior part of the lower extremity between the KNEE and the ANKLE.
The total volume of gas inspired or expired per unit of time, usually measured in liters per minute.
A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The use of a bicycle for transportation or recreation. It does not include the use of a bicycle in studying the body's response to physical exertion (BICYCLE ERGOMETRY TEST see EXERCISE TEST).
Glycogenosis due to muscle phosphorylase deficiency. Characterized by painful cramps following sustained exercise.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
The ability to carry out daily tasks and perform physical activities in a highly functional state, often as a result of physical conditioning.
A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
Diet modification and physical exercise to improve the ability of animals to perform physical activities.
Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
The chemical reactions involved in the production and utilization of various forms of energy in cells.
Glucose in blood.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
The flow of BLOOD through or around an organ or region of the body.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
A type of strength-building exercise program that requires the body muscle to exert a force against some form of resistance, such as weight, stretch bands, water, or immovable objects. Resistance exercise is a combination of static and dynamic contractions involving shortening and lengthening of skeletal muscles.
The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
The hollow, muscular organ that maintains the circulation of the blood.
An activity in which the body is propelled by moving the legs rapidly. Running is performed at a moderate to rapid pace and should be differentiated from JOGGING, which is performed at a much slower pace.
A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.
The giving of drugs, chemicals, or other substances by mouth.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Exercises that stretch the muscle fibers with the aim to increase muscle-tendon FLEXIBILITY, improve RANGE OF MOTION or musculoskeletal function, and prevent injuries. There are various types of stretching techniques including active, passive (relaxed), static, dynamic (gentle), ballistic (forced), isometric, and others.
A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
The physical or mechanical action of the LUNGS; DIAPHRAGM; RIBS; and CHEST WALL during respiration. It includes airflow, lung volume, neural and reflex controls, mechanoreceptors, breathing patterns, etc.
Drugs used to cause dilation of the blood vessels.
The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.
The superior part of the upper extremity between the SHOULDER and the ELBOW.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.
Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.
A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Force exerted when gripping or grasping.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Pathological conditions involving the HEART including its structural and functional abnormalities.
Contractile activity of the MYOCARDIUM.
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY.
Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.
The ability of organisms to sense and adapt to high concentrations of salt in their growth environment.
Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).
Benzo-indoles similar to CARBOLINES which are pyrido-indoles. In plants, carbazoles are derived from indole and form some of the INDOLE ALKALOIDS.
The relationship between the dose of an administered drug and the response of the organism to the drug.
A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
Drugs that selectively bind to and activate beta-adrenergic receptors.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
The excision of lung tissue including partial or total lung lobectomy.
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Methods or programs of physical activities which can be used to promote, maintain, or restore the physical and physiological well-being of an individual.
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
The performance of the basic activities of self care, such as dressing, ambulation, or eating.
An angiotensin-converting enzyme inhibitor that is used to treat HYPERTENSION and HEART FAILURE.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
A sport in which weights are lifted competitively or as an exercise.
Adaptation to a new environment or to a change in the old.
The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
The physical activity of a human or an animal as a behavioral phenomenon.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
The circulation of blood through the CORONARY VESSELS of the HEART.
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.
Therapy with two or more separate preparations given for a combined effect.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Prolonged dry periods in natural climate cycle. They are slow-onset phenomena caused by rainfall deficit combined with other predisposing factors.
The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Activities or games, usually involving physical effort or skill. Reasons for engagement in sports include pleasure, competition, and/or financial reward.
Processes and properties of the CARDIOVASCULAR SYSTEM as a whole or of any of its parts.
The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.
A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.
Any method of measuring the amount of work done by an organism, usually during PHYSICAL EXERTION. Ergometry also includes measures of power. Some instruments used in these determinations include the hand crank and the bicycle ergometer.
Pathological processes involving any part of the LUNG.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
The quadriceps femoris. A collective name of the four-headed skeletal muscle of the thigh, comprised of the rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis.
The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished through a variety of means including CLONAL ANERGY and CLONAL DELETION.
Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
The relative amounts of various components in the body, such as percentage of body fat.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
An activity in which the body is propelled through water by specific movement of the arms and/or the legs. Swimming as propulsion through water by the movement of limbs, tail, or fins of animals is often studied as a form of PHYSICAL EXERTION or endurance.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
The process of exocrine secretion of the SWEAT GLANDS, including the aqueous sweat from the ECCRINE GLANDS and the complex viscous fluids of the APOCRINE GLANDS.
FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
An absence of warmth or heat or a temperature notably below an accustomed norm.
Part of the arm in humans and primates extending from the ELBOW to the WRIST.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.
The condition that results from excessive loss of water from a living organism.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)
The measure of the level of heat of a human or animal.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)

Echo derived variables predicting exercise tolerance in patients with dilated and poorly functioning left ventricle. (1/1872)

OBJECTIVE: To determine whether resting echo derived measurements predict exercise tolerance and its interrelation with heart rate response and ventilation drive in patients with systolic left ventricular disease. DESIGN: Prospective echocardiographic examination followed by cardiopulmonary exercise testing. SETTING: A tertiary referral centre for cardiac diseases. SUBJECTS: 21 patients (11 with coronary artery disease, 10 with idiopathic dilated cardiomyopathy) with end diastolic dimension > 6.4 cm, shortening fraction < 25%, and in sinus rhythm. There were 11 age matched normal controls. RESULTS: In the patients, peak oxygen consumption (mVo2) correlated with right ventricular long axis excursion (r = 0.62); 65% of the variance in mVo2 was predictable using a multivariate model with right ventricular long axis excursion and peak lengthening rate, and peak mitral atrial filling velocity as independent variables. Aetiology was not an independent predictor, although the right ventricular long axis excursion (mean (SD)) was greater in patients with idiopathic dilated cardiomyopathy than in those with coronary artery disease (2.4 (0.5) cm v 1.6 (0.5) cm, p < 0.001). Peak heart rate correlated with duration of mitral regurgitation (r = -0.52) and the slope of ventilation against CO2 production correlated with M mode isovolumic relaxation time (r = 0.61). CONCLUSIONS: In patients with systolic left ventricular dysfunction, more than half the variance in exercise tolerance can be predicted by factors measured on echocardiography at rest, particularly right ventricular long axis excursion.  (+info)

Cardiac metaiodobenzylguanidine uptake in patients with moderate chronic heart failure: relationship with peak oxygen uptake and prognosis. (2/1872)

OBJECTIVES: This prospective study was undertaken to correlate early and late metaiodobenzylguanidine (MIBG) cardiac uptake with cardiac hemodynamics and exercise capacity in patients with heart failure and to compare their prognostic values with that of peak oxygen uptake (VO2). BACKGROUND: The cardiac fixation of MIBG reflects presynaptic uptake and is reduced in heart failure. Whether it is related to exercise capacity and has better prognostic value than peak VO2 is unknown. METHODS: Ninety-three patients with heart failure (ejection fraction <45%) were studied with planar MIBG imaging, cardiopulmonary exercise tests and hemodynamics (n = 44). Early (20 min) and late (4 h) MIBG acquisition, as well as their ratio (washout, WO) were determined. Prognostic value was assessed by survival curves (Kaplan-Meier method) and uni- and multivariate Cox analyses. RESULTS: Late cardiac MIBG uptake was reduced (131+/-20%, normal values 192+/-42%) and correlated with ejection fraction (r = 0.49), cardiac index (r = 0.40) and pulmonary wedge pressure (r = -0.35). There was a significant correlation between peak VO2 and MIBG uptake (r = 0.41, p < 0.0001). With a mean follow-up of 10+/-8 months, both late MIBG uptake (p = 0.04) and peak VO2 (p < 0.0001) were predictive of death or heart transplantation, but only peak VO2 emerged by multivariate analysis. Neither early MIBG uptake nor WO yielded significant insights beyond those provided by late MIBG uptake. CONCLUSIONS: Metaiodobenzylguanidine uptake has prognostic value in patients with wide ranges of heart failure, but peak VO2 remains the most powerful prognostic index.  (+info)

Diagnostic utility of metabolic exercise testing in a patient with cardiovascular disease. (3/1872)

Disproportionate exercise limitation in patients with cardiovascular disease is a common problem faced by clinical cardiologists and other physicians. Symptoms may be attributed to psychological factors or hypothetical pathophysiological mechanisms that are difficult to confirm clinically. This case report describes how the use of metabolic exercise testing in a 28 year old woman with morphologically and haemodynamically mild hypertrophic cardiomyopathy and severe exercise limitation led to the diagnosis of an alternative cause for the patient's symptoms, namely a primary disturbance of the mitochondrial respiratory chain probably caused by a nuclear encoded gene defect.  (+info)

Effect of thoracotomy and lung resection on exercise capacity in patients with lung cancer. (4/1872)

BACKGROUND: Resection is the treatment of choice for lung cancer, but may cause impaired cardiopulmonary function with an adverse effect on quality of life. Few studies have considered the effects of thoracotomy alone on lung function, and whether the operation itself can impair subsequent exercise capacity. METHODS: Patients being considered for lung resection (n = 106) underwent full static and dynamic pulmonary function testing which was repeated 3-6 months after surgery (n = 53). RESULTS: Thoracotomy alone (n = 13) produced a reduction in forced expiratory volume in one second (FEV1; mean (SE) 2.10 (0.16) versus 1.87 (0.15) l; p<0.05). Wedge resection (n = 13) produced a non-significant reduction in total lung capacity (TLC) only. Lobectomy (n = 14) reduced forced vital capacity (FVC), TLC, and carbon monoxide transfer factor but exercise capacity was unchanged. Only pneumonectomy (n = 13) reduced exercise capacity by 28% (PVO2 23.9 (1.5) versus 17.2 (1.7) ml/min/kg; difference (95% CI) 6.72 (3.15 to 10.28); p<0.01) and three patients changed from a cardiac limitation to exercise before pneumonectomy to pulmonary limitation afterwards. CONCLUSIONS: Neither thoracotomy alone nor limited lung resection has a significant effect on exercise capacity. Only pneumonectomy is associated with impaired exercise performance, and then perhaps not as much as might be expected.  (+info)

Validity of a modified shuttle test in adult cystic fibrosis. (5/1872)

BACKGROUND: The purpose of this study was to provide some evidence of the validity of a modified shuttle test (MST) by comparing performance on the MST with peak oxygen consumption (VO2peak) measured during a treadmill test in a group of adult patients with cystic fibrosis. METHOD: Twenty patients with stable cystic fibrosis performed a ramped maximal treadmill test (STEEP protocol) and the MST using a randomised balanced design. RESULTS: The relationship between the distance achieved on the MST and VO2peak was strong (r = 0.95, p<0.01) with 90% of the variance in VO2peak explained by the variance in MST distance. The relationship was represented by the regression equation (with 95% confidence intervals) VO2peak = 6.83 (2.85 to 10.80) + 0.028 (0.019 to 0.024) x MST distance. CONCLUSION: This study provides evidence of the construct validity of the MST as an objective measure of exercise capacity in adults with cystic fibrosis.  (+info)

Effects of L-arginine on lower limb vasodilator reserve and exercise capacity in patients with chronic heart failure. (6/1872)

OBJECTIVE: To determine whether the reactive hyperaemic response of the lower limb increases with improved exercise capacity after acute supplementation with L-arginine, the precursor of nitric oxide, in patients with chronic heart failure. METHODS: 19 patients with chronic heart failure were enrolled in the study. Rest calf blood flow and femoral occlusion induced calf blood flow changes were measured by venous occlusion plethysmography before and after intravenous infusion of 10% L-arginine solution (5 ml/kg for 30 minutes) or placebo. Postexercise calf blood flow was also measured after the experimental infusion. During both postinfusion periods, several exercise capacity indices were determined by a symptom limited cardiopulmonary exercise test using a bicycle ergometer. RESULTS: Baseline calf blood flow, systemic blood pressure, and heart rate showed no significant changes in either of the two experimental conditions. However, the occlusion induced blood flow response was significantly enhanced by L-arginine infusion (mean (SEM) peak flow, 19.6 (1.5) v 28.9 (3.1) ml/min/dl calf tissue; p < 0.01), but not by placebo (peak flow, 19.1 (1.4) v 20.9 (1.8) ml/min/dl calf tissue; NS). Calf blood flow response after exercise was also higher after L-arginine infusion than after placebo (peak flow, 4.8 (0.4) v 6.0 (0.8) ml/min/dl calf tissue; p < 0.05). L-arginine infusion had no significant effect compared with placebo on exercise capacity indices such as peak oxygen uptake (17.1 (1.0) v 15.8 (1.1) ml/min/kg; NS), anaerobic threshold (10.5 (0.6) v 10.4 (0.7) ml/min/kg; NS), and exercise time (296 (23) v 283 (22) s; NS). CONCLUSIONS: Acute supplementation with the nitric oxide precursor L-arginine increased lower limb reactive hyperaemia but did not lead to any significant improvement in exercise capacity in patients with chronic heart failure.  (+info)

Ventricular dilatation in the absence of ACE inhibitors: influence of haemodynamic and neurohormonal variables following myocardial infarction. (7/1872)

OBJECTIVE: To examine the relation between patterns of ventricular remodelling and haemodynamic and neurohormonal variables, at rest and during symptom limited exercise, in the year following acute myocardial infarction in patients not receiving angiotensin converting enzyme (ACE) inhibitors. DESIGN: A prospective observational study. PATIENTS: 65 patients recruited following hospital admission with a transmural anterior myocardial infarction. METHODS: Central haemodynamics and neurohormonal activation at rest and during symptom limited treadmill exercise were measured at baseline before hospital discharge, one month later, and at three monthly intervals thereafter. PATIENTS were classified according to individual patterns of change in left ventricular end diastolic volumes at rest, assessed at each visit using transthoracic echocardiography. RESULTS: In most patients (n = 43, 66%) ventricular volumes were unchanged or reduced. Mean (SEM) treadmill exercise capacity and peak exercise cardiac index increased at month 12 by 200 (24) seconds (p < 0.001 v baseline) and by 0.8 (0.4) l/min/m2 (p<0.05 v baseline), respectively, in this group. In patients with limited ventricular dilatation (n = 11, 17%) exercise capacity increased by 259 (52) seconds (p < 0.001 v baseline) and peak exercise cardiac index improved by 0.8 (0.7) l/min/m2 (NS). In the remaining 11 patients with progressive left ventricular dilatation, exercise capacity increased by 308 (53) seconds (p< 0. 001 v baseline) and peak exercise cardiac index similarly improved by 1.3 (0.7) l/min/m2 (NS). There were trends towards increased atrial natriuretic factor (ANF) secretion at rest and at peak exercise in this group. CONCLUSIONS: Ventricular dilatation after acute myocardial infarction is a heterogeneous process that is progressive in only a minority of patients. Compensatory mechanisms, including ANF release, appear capable of maintaining and improving exercise capacity in most patients for at least 12 months, even in those with a progressive increase in ventricular size.  (+info)

Physiological basis of improvement after lung volume reduction surgery for severe emphysema: where are we? (8/1872)

Lung volume reduction surgery has become an accepted therapeutic option to relieve the symptoms of selected patients with severe emphysema. In a majority of these patients, it causes objective as well as subjective functional improvement. A proper understanding of the physiological determinants underlying these beneficial effects appears very important in order to better select patients for the procedure that is currently largely carried out on an empirical basis. Lung volume reduction surgery has two distinct effects. Firstly, it causes an increased elastic recoil, which at least partially explains the enhanced maximal expiratory flow. Secondly, it is associated with a reduction of hyperinflation which allows for an increase in global inspiratory muscle strength and in diaphragmatic contribution to tidal volume as well as a decrease in the inspiratory elastic load imposed by the chest wall. Taken together, these effects result in a reduced work of breathing and in an enhanced maximal ventilation which both contribute to the increased exercise capacity and reduced dyspnoea after surgery. The improved lung recoil and the reduced hyperinflation after volume reduction surgery were the primary postulates upon which the usual selection criteria for the procedure were based. It is now likely that these are correct. Nevertheless, some patients do not benefit from lung volume reduction surgery and the current literature does not allow for a refinement of the selection process from a physiological point of view. The exact mechanisms underlying the improvement in lung recoil, lung mechanics, and respiratory muscle function remain incompletely understood. Moreover, the effects of lung volume reduction surgery on gas exchange and pulmonary haemodynamics still need to be more fully investigated. An analysis of the characteristics of patients who do not benefit from the procedure and the development of an animal model for lung volume reduction surgery would probably help address these important issues.  (+info)

Intermittent hypoxia has been suggested to increase exercise tolerance by enhancing stress resistance and improving oxygen delivery. Because the improvement of exercise tolerance reduces mortality in the elderly with and without coronary artery disease intermittent hypoxia might be a valuable preventive and therapeutic tool. However, controlled studies are lacking. Sixteen males (50-70 years, 8 with and 8 without prior myocardial infarction) were randomly assigned in a double-blind fashion to receive 15 sessions of passive intermittent hypoxia (hypoxia group) or normoxia (control group) within 3 weeks. For the hypoxia group each session consisted of three to five hypoxic (14-10% oxygen) periods (3-5 min) with 3-min normoxic intervals. Controls inhaled only normoxic air in the same way. Exercise tests were performed before and after the 3-week breathing program. After 3 weeks of intermittent hypoxia peak oxygen consumption had increased compared to normoxic conditions (+ 6.2% vs.-3%, p , 0.001). ...
The effect of oral and intravenous tolamolol on exercise tolerance was assessed in 11 patients with angina pectoris. Patients were selected on the basis of an absence of placebo response and the reliable reproducibility of anginal pain and electrocardiographic changes with exercise on a constant load Schönander-Elema bicycle ergometer. The effect of tolamolol on exercise time and heart rate was compared with that of propranolol. Tolamolol was shown to increase exercise tolerance and the effect was comparable to that of propranolol. Tolamolol did not produce a significant increase in airways resistance nor were any untoward side effects noted.. ...
The relations of systolic and diastolic blood pressures to alcohol intake and exercise tolerance levels in 15,612 men and 3,855 women were investigated. Alcohol intake was assessed by questionnaire and stratified into seven levels for men and six for women according to the ounces of ethanol consumed per week. Exercise tolerance was determined by maximal treadmill exercise testing and was categorized into six age-specific by sex-specific levels. Both systolic and diastolic blood pressure were significantly related to both alcohol intake and exercise tolerance levels in both men and women. These relations, which were positive for alcohol and negative for exercise tolerance, remained after covariance adjustment for age, body mass index, and cigarette smoking. Alcohol intake was not significantly correlated with exercise tolerance. The relation of blood pressure to alcohol was not linear because the blood pressure of moderate consumers of alcohol tended to be slightly lower than that of nondrinkers. ...
In 50 patients with chronic bronchitis the relation was assessed between exercise tolerance and pulmonary function and psychological factors, including subjective perception of exertion, mood, general psychiatric disturbance, and the attitudes and beliefs held by patients concerning themselves, their illness, and its treatment. Ventilatory capacity was significantly correlated with but a poor predictor of exercise tolerance. Subjective perception of exertion was most closely correlated with exercise tolerance. The distance walked in a 12-minute exercise test was significantly correlated with measurements of mood and with several attitudes and beliefs. Attitudes and beliefs greatly outweighed measurements of mood and ventilatory capacity as components in a multiple regression predicting distance walked in 12 minutes. This method of psychological assessment emphasises the importance of attitudes and beliefs in respiratory disability and may have useful applications in rehabilitation in other ...
TY - JOUR. T1 - Effect of once weekly pulmonary rehabilitation on exercise tolerance in patients with chronic lung disease.. AU - ONeill, Brenda. AU - Johnston, D. AU - Burrell, N. AU - MacMahon, J. PY - 2001/10. Y1 - 2001/10. U2 - 10.1007/BF03167784. DO - 10.1007/BF03167784. M3 - Article. VL - 170. SP - 231. EP - 232. JO - IRISH JOURNAL OF MEDICAL SCIENCE. JF - IRISH JOURNAL OF MEDICAL SCIENCE. SN - 0021-1265. ER - ...
The most disturbing aspect of Cystic Fibrosis (CF) is the associated premature death. Low exercise capacity predicts death in patients with CF and is also associated with a steeper decline in lung function and more lung infections. A critical barrier to improving exercise tolerance in patients with CF is the investigators lack of knowledge regarding the different physiological mechanisms which contribute to their lower exercise capacity. We have compelling data to indicate that the blood vessels may contribute to the low exercise capacity in CF. The impact of this proof of concept investigation will test Phosphodiesterase Type 5 inhibitors (PDE5) inhibitors as a potential therapy in CF and will explore blood flow and endothelial function as potential mechanisms which contribute to exercise intolerance in CF. Improvements in exercise capacity will not only contribute to a better quality of live for patients with CF, it will also increase longevity in these patients ...
Introduction: Advanced heart failure (HF) patients may stay for a long period of time in the hospital for the treatment of HF and prolonged inactivity causes complications that result in worsening of exercise tolerance. On the other hand, there is evidence that treatment with muscle low-frequency electrical stimulation (FES) provides important benefits for HF patients. This study investigated the effects of FES on neurovascular control and exercise tolerance in HF hospitalized patients.. Methods and results: Thirty hospitalized patients for treatment of decompensated HF, functional class IV NYHA and ejection fraction ≤ 30% were consecutively randomised into two groups: 1) FES(n= 15; 54±2 years) and control(n= 15; 49±2 years). Muscle sympathetic nerve activity (MSNA) was directly recorded via microneurography and blood flow by venous occlusion plethysmography. Heart rate and blood pressure were evaluated on a beat-to-beat basis (Finometer). Exercise tolerance by six-minute walk test, ...
At The Cardiac Unit we use an Exercise Tolerance Test (ETT) to record the hearts electrical activity and blood pressure during exercise. Book now.
All participants will receive a personalised programme of exercise during the pulmonary rehabilitation session and a home-based programme designed according to their individual needs. We expect that all patients will experience improvement in exercise capacity and breathlessness regardless of the group they belong to. If the intervention (HIIT) is successful, the active group is likely to experience additional benefits. All patients will benefit from the educational sessions that are part of the pulmonary rehabilitation programme. Another benefit for patients is that they will be able to express their views about their programme and care and will be encouraged to set goals to improve their quality of life. Again, this benefit is independent of the group the patients will belong to. There are no major anticipated risks from the programme and all assessments are non-invasive. Both groups, active and control, will receive the standard treatment (pulmonary rehabilitation). Both types of training ...
Exercise tolerance and cardiorespiratory adjustments at peak work capacity (PWC) were determined in 20 patients with cystic fibrosis (CF) during progressive cycle ergometry. The results were related to resting lung function tests, expressed by a pulmonary function score (PFS) that ranged from 0 (no …
Background: Inherited disorders of long-chain fatty acid oxidation (FAO) inhibit the ability to oxidize long-chain fatty acids (LCFAs) for energy generation. As a result, bouts of exercise can lead to rhabdomyolysis, impaired cardiac function and, hence, exercise avoidance in these individuals. Medium-chain triglyceride (MCT) supplementation may bypass this defect and reduce the risk of adverse metabolic events. Objectives: To determine the influence of isocaloric MCT vs carbohydrate (CHO) supplementation prior to exercise on substrate oxidation and cardiac function during exercise in participants with long-chain FAO disorders. Design & Methods: Two 45-minute, moderate intensity treadmill exercise studies were completed by subjects (n=11) in a randomized crossover design. An isocaloric oral dose of CHO (1 g/kg LBM) or MCT-oil (0.5 g/kg LBM) was administered prior to exercise, hemodynamic and metabolic indices were assessed during exertion and a cardiac echocardiogram was performed following exercise.
The aim of this study is to test our hypothesis that normal exercise tolerance differs according to gender and to identify potential functional cardiac relationships, which could explain those differences. A total of 44 healthy individuals with mean age of 49 ± 12 years (28-74 years, 22 males) constituted the study cohort. All individuals underwent resting and exercise Doppler echocardiogram simultaneously with peak oxygen uptake analysis (pVO(2)). At equal pVO(2), males achieved higher peak exercise workload (p , 0.001) and females higher heart rate (p , 0.001) but the two groups maintained similar indexed left ventricular (LV) stroke volume (SV) and cardiac output. Indexed LV end-diastolic (LVDVI) and end-systolic volumes (LVSVI) were smaller in females (p , 0.001 and p , 0.01, respectively), but filling time (FT) was shorter (p , 0.001) and they had higher early diastolic (E) velocity (p = 0.004), E/E (m) (myocardial E velocity) (p , 0.001) and global longitudinal strain rate atrial velocity ...
For the primary (dichotomous) outcome, relative risks (RRs) and 95% CI were computed using random-effects models (11). The weighted MD and corresponding 95% CI were computed using random-effects models for continuous variables. Between-studies heterogeneity was assessed using the Cochran Q test (based on the pooled RR by Mantel-Haenszel), as well as by measuring inconsistency (I2 [the percentage of total variance across studies attributable to heterogeneity rather than chance]) of treatment effects across trials (12). We used Beggs funnel plot to assess for publication bias for the primary outcome of all-cause mortality (13). Quality assessment of the analyzed RCTs was performed by Jadads method (14). Since the majority of included studies (13 of 14 treatment arms) had a quality score of 4/4 for mortality, suggesting high quality, a formal quality score and/or weighting of results was not calculated. For exercise capacity, only 1 study had nonblinded assessment of outcome. As a number of ...
Our Pulmonary Rehabilitation Program is designed to provide individualized care to patients who have diseases of the lungs such as pneumonia, emphysema, pulmonary embolism and lung cancer, as well as sleep apnea.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Exercise and physical activity should be considered as therapeutic options for lung cancer as they have been shown to reduce symptoms, increase exercise tolerance, improve quality of life, and potentially reduce length of hospital stay and complications following surgery for lung cancer.
Optimal pharmacological treatment for COPD patients reduces symptoms, reduces the frequency and severity of exacerbations, improve health status and increases exercise tolerance. Unfortunately, despite frequent changes in COPD classification systems and the emergence of new inhaled therapies recommended from evidence-based guidelines, poor adherence to treatment due to the cost of medication and lack of availability of medications create a gap in real-life prescribing patterns (Cases et al, 2018).
Coenzyme Q10 (CoQ10), a nutrient that occurs naturally in every cell in the body, improved blood-vessel function and increased peak exercise capacity in those with heart disease, in two new studies. In a coronary artery disease (CAD) study, researchers recruited 33 men and five women with an average age of 55, who had CAD and whose hearts pumped blood normally, to take 300 mg of CoQ10 in three 100 mg doses per day or a placebo for one month. Doctors measured the activity of an important antioxidant enzyme, superoxide dismutase or SOD, on blood vessel walls, which declines in CAD. They found that those who had taken CoQ10 had a 29% increase in SOD activity compared to 4% for placebo. Scientists also measured the ability of the arteries to relax (dilate), the ability of the heart to deliver oxygen and the capacity of the cells to absorb oxygen, and found that, in all three measures, those who had taken CoQ10 had significantly greater improvement compared to placebo. Doctors noted that participants ...
The effect of our home CR programme on exercise capacity is consistent with the findings in the only other study investigating the effect of home-based CR and usual care among elderly with coronary heart disease.3 In this study, patients in the age groups 45-65 years, 66-75 years and ,75 years significantly improved their exercise capacity after participating in a home programme, although the improvement was less among the very old patients (,75 years).. The meta-analysis by Jolly et al,12 which included studies of all age groups, investigated the effect of home-based CR and usual care. The meta-analysis showed an improvement in exercise capacity but could not identify any significant differences between the home and usual care group. The authors explained this by the possibility that patients in usual care groups may receive input that match the homeinterventions and thus diminish a possible difference. This could also have been the case in our study.. At 12 months, a significant decline in ...
The Paperback of the Conditioning for Outdoor Fitness: Functional Exercise and Nutrition for Everyone, 2nd Edition by Mark Pierce, A.T.C., David Musnick,
Background Patients with COPD have an increased risk of cardiovascular disease. Whilst pulmonary rehabilitation has proven benefit for exercise tolerance and quality of life, any effect on...
New research is investigating a possible connection between memories of physical activity at school and the amount of exercise taken in adult life.
Patients with COPD have reduced exercise tolerance. Low tolerance to physical exercise in patients with COPD is multifactorial and is due to several reasons, rather important of which is reduction of lung ventilation ability. Registration of indices of ventilation during the test widens diagnostic possibilities of 6-minute walk test (6 MWT).. Materials and methods: male patients with COPD (n=34) II-IV degree of severity, average age 57,5±7,1, FEV146,8 ±14,3% predicted and male patients without COPD, average age 60,8±4,6, FEV193,3±14,4% predicted are involved in the investigation. This investigation was held on the equipment Spiropalm 6 MWT (Cosmed, Italy), which allows to measure parameters of minute ventilation (VE) in the process of standardized 6 MWT.. Results: distance, walked by patients with COPD was 362,3 ± 10,3 m and in control group 510,4 ± 15,6 (p,0,05). Indices of initial ventilation in groups werent significantly different VE 8,9±3,6 l / min in group of patients with COPD and ...
Health, ...THURSDAY Sept. 22 (HealthDay News) -- A cardiac rehabilitation progra... Overall following the cardiac rehab intervention the TIA and mild s...The investigators looked at 80 of 100 patients whod had a stroke or T...The peak exercise capacity of the patients improved by an average of a...,Cardiac,Rehab,May,Cut,Risk,Factors,After,Mini-Stroke,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Nagging pain on right side - I went for a short power walk today after work and toward I started getting a nagging side stitch that made me slow down. How do I avoid this? Exercise intolerance. In a young female who is otherwise healthy, discomfort in the lower chest and upper abdomen may be related to exercise intolerance. The person needs to gradually increase their tolerance and insurance, however, if the symptoms are persistent the person needs evaluation of the cardiorespiratory system. You may get alternative points of view from other healthtap physicians
Find out what alcohol really does to your body, and how it affects exercise and recovery. Plus get the truth about hangover cures. - Natural Health Resource - The worlds most widely referenced, open access, natural medicine database, with 30,000+ study abstracts and growing daily
Buy Pump-HD 30 servings at TFSupplements. Pump-HD is the premier pre-workout muscle builder, formulated with well-researched, trialed and tested ingredients proven to build muscle and increase exercise performance.
- Increases cardiovascular endurance and burns calories - Can be used in functional exercises such as: squatting, lifting, throwing and standing - Weight: 6 kg
Background Patients with pulmonary arterial hypertension who achieve a six-minute walk distance of 380-440 m may have improved prognosis. Using the randomized controlled trial of macitentan in pulmonary arterial hypertension (SERAPHIN), the association between six-minute walk distance and long-term outcomes was explored. Methods Patients with six-minute walk distance data at Month 6 were dichotomized as above or below the median six-minute walk distance (400 m) and assessed for future risk of pulmonary arterial hypertension-related death or hospitalization and all-cause death. Additionally, six-minute walk distance values at baseline, Month 6 and the change from baseline to Month 6 were categorized by quartiles. All associations were analyzed by the Kaplan-Meier method using a log-rank test and Cox regression models. Results Patients with a six-minute walk distance |400 m vs. ≤400 m at Month 6 have a reduced risk of pulmonary arterial hypertension-related death or hospitalization (hazard ratio 0
BACKGROUND/AIM Peripheral muscle weakness and nutritional disorders, firstly loss of body weight, are common findings in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to analyse the impact of pulmonary function parameters, nutritional status and state of peripheral skeletal muscles on exercise tolerance and development of dyspnea in COPD patients. METHODS Thirty COPD patients in stable state of disease were analyzed. Standard pulmonary function tests, including spirometry, body pletysmography, and measurements of diffusion capacity were performed. The 6-minute walking distance test (6MWD) was done in order to assess exercise tolerance. Level of dyspnea was measured with Borg scale. In all patients midthigh muscle cross-sectional area (MTCSA) was measured by computerized tomography scan. Nutritional status of patients was estimated according to body mass index (BMI). RESULTS Statisticaly significant correlations were found between parameters of pulmonary
This study was designed to determine the need for a practice walk for the endurance shuttle walk test (ESWT) following the performance of two incremental shuttle walk tests (ISWTs) †one practice and one test †on the same day. Forty-four patients with a primary diagnosis of chronic obstructive pulmonary disease were included in the study. The mean age of the group was 67.6 years and mean forced expiratory volume in 1 second was 37% predicted. ...
TY - JOUR. T1 - Design and validation of an interpretative strategy for cardiopulmonary exercise tests. AU - Schmid, Andreas. AU - Schilter, Daniel. AU - Fengels, Ingo. AU - Chhajed, Prashant N.. AU - Strobel, Werner. AU - Tamm, Michael. AU - Brutsche, Martin H.. PY - 2007/11. Y1 - 2007/11. N2 - Background and objective: Cardiopulmonary exercise testing (CPET) is a common investigation for the evaluation of exertional dyspnoea. At present, there is no consensus on the best interpretative strategy and none of the available algorithms have been validated. The aim of this study was to develop and validate a standardized strategy for the interpretation of CPET. Methods: This study analysed 199 CPETs from patients with exertional dyspnoea. Using a set of 100 CPETs a standardized interpretation using a four-step approach was developed that scored: examination quality, performance, exercise limitation and cofactors. A second set of 99 CPETs was interpreted by two experts in the field, initially ...
Barth syndrome (BTHS) is an X-linked disorder caused by defects in TAZ with key clinical features including cardiomyopathy, neutropenia and skeletal myopathy. In order to gain a better understanding of the range of clinical features, identify targets for monitoring, and increase knowledge of natural history of the disease, we conducted muscle strength testing, functional exercise capacity testing, physical activity assessment, balance assessment and motion reaction time testing in 33 affected individuals and 14 controls. We analyzed data points to provide a cross-sectional quantitative spectrum of disease characteristics. We also compared these data points to the matched data points collected two years prior to provide insight into effects of BTHS over time. In comparison to controls, pediatric subjects with BTHS present with significantly impaired balance and motion reaction time while adult subjects with BTHS present with significantly impaired motion reaction time. In comparison to controls, subjects
Introduction: The aim of the study was to determine the impact of systematic individual Nordic Walking training on physical performance in older men. Material and methods: The study included 18 men (aged 52 to 73), divided into two groups. Group I (the experimental group) underwent an 8-week Nordic Walking training, while group II (the control group) did not perform any physical activity during the analyzed period. The level of physical exercise tolerance was assessed twice: at the beginning and after eight weeks of the study period using the Finnish walking test and the 30-minute walking test. The results were analyzed with the use of Statistica 10. software. Results: The results of the initial Finnish walking test show that the average values of the Fitness Index, time of a 2-kilometer distance coverage and HR were similar in both study groups. After 8 weeks, a statistically significant improvement in exercise tolerance was observed in the experimental group. Aerobic endurance evaluated on the ...
Left atrial volume (LAV) and exercise capacity are important prognostic determinants of cardiovascular risk. Exercise intolerance and increased LAV are expected in patients with diastolic dysfunction. While dyspnea is the symptom reported by the patient and considered subjective, exercise capacity obtained by exercise testing provides an objective measure of cardiovascular fitness. The objective of this study is to determine the relationship between LAV index and exercise capacity in patients with isolated diastolic dysfunction who presented with exertional dyspnea. We studied consecutive patients with dyspnea who underwent treadmill exercise testing and transthoracic echocardiography on the same day. LAV was assessed using the biplane area-length method. Symptom-limited exercise testing was performed immediately after echocardiography. Patients with coronary artery disease, valvular or congenital heart disease, left ventricular systolic dysfunction, pulmonary hypertension or positive exercise test were
A paucity of studies has examined the effect of exercise training after left ventricular assist device (LVAD) implantation. Previous research has demonstrated t
The Pulmonary Rehabilitation Program offers education and exercise sessions to clients with Chronic Obstructive Pulmonary Disease (COPD) to help them manage their condition and encourage them to lead an active lifestyle * nine weeks in length and consists of two sessions per week each lasting 2.5 hours and includes an initial assessment with a COPD Educator and a physiotherapist as well as a cardiopulmonary exercise test (CPX) prior to commencing the ...
Background Oxygen uptake efficiency (OUE), the relation between oxygen uptake (VO2) and minute ventilation (VE), differs between healthy children and children with heart disease. This study aimed to investigate the normal response profiles of OUE during a progressive cardiopulmonary exercise test. Design: Cross-sectional. Methods Healthy children between eight and 19 years of age (114 boys and 100 girls, mean ± SD age 12.7 ± 2.8 years) performed a maximal cardiopulmonary exercise test. Peak VO2 (VO2peak), ventilatory threshold and peak VE were determined. OUE was determined by the OUE plateau (OUEP), OUE at the ventilatory threshold ([email protected]) and OUE slope (OUES). Results OUEP (42.4 ± 4.6) and [email protected] (41.9 ± 4.7) were similar and less variable than OUES (2138 ± 703). OUEP correlated strongly with [email protected] (r = 0.974); however, OUEP was weak-to-moderately correlated with VO2peak (r = 0.646), the ventilatory threshold (r = 0.548) and OUES (r = 0.589). OUES correlated strongly with VO2peak (r = ...
Pulmonary rehabilitation is known to be a beneficial treatment for COPD patients. To date, however, there is no agreement for how long a rehabilitation program should be implemented. In addition, current views are that pulmonary rehabilitation does not improve FEV1 or even slow its decline in COPD patients. The aim of the study was to examine the efficacy of a 3 year outpatient pulmonary rehabilitation (PR) program for COPD patients on pulmonary function, exercise capability, and body mass index (BMI). A matched controlled trial was performed with outcome assessments evaluated at 6, 12, 18, 24, 30, and 36 months. Eighty patients with moderate to severe COPD (age 63 ± 7 years; FEV1 48% ± 14) were recruited. The control group received standard care only, while in addition, the case study group received PR for duration of three years. These groups were matched for age, sex, BMI, FEV1% and number of pack-years smoked. The decline in FEV1 after the three years was significantly lower in the PR group
TY - JOUR. T1 - Relation of right ventricular mechanics to exercise tolerance in children after tetralogy of Fallot repair. AU - Friedberg, Mark K.. AU - Fernandes, Fernanda P.. AU - Roche, Susan L.. AU - Slorach, Cameron. AU - Grosse-Wortmann, Lars. AU - Manlhiot, Cedric. AU - Fackoury, Cheryl. AU - McCrindle, Brian W.. AU - Mertens, Luc. AU - Kantor, Paul F.. N1 - Funding Information: This work was supported by the National Grants Program of the Canadian Institutes of Health Research and Sickkids Foundation . The authors are solely responsible for the design and conduct of this study; all study analyses, the drafting and editing of the paper, and its final contents. PY - 2013/4. Y1 - 2013/4. N2 - Background Progressive right ventricular (RV) dysfunction and exercise intolerance are common problems after tetralogy of Fallot (TOF) repair. We investigated RV myocardial deformation and dyssynchrony in children after TOF repair and their association with exercise capacity. Methods Asymptomatic ... Decreased oxygen extraction during cardiopulmonary exercise test in patients with...
Riversides Pulmonary Rehabilitation program treats patients who suffer from chronic respiratory diseases, such as lung disease, emphysema, chronic bronchitis, asthma and chronic obstructive pulmonary disease (COPD).
This essay expounds on fundamental, quantitative elements of the exercise ventilation in children, which was the subject of the Tom Rowland Lecture given at the NASPEM 2018 Conference. Our knowledge about how much ventilation rises during aerobic exercise is reasonably solid; our understanding of its governance is a work in progress, but our grasp of dyspnea and ventilatory limitation in children (if it occurs) remains embryonic. This manuscript summarizes ventilatory mechanics during dynamic exercise, then proceeds to outline our current understanding of mechanisms of dyspnea, particularly during exercise (exertional dyspnea). Most research in this field has been done in adults, and the vast majority of these studies in patients with chronic obstructive pulmonary disease. To what extent conclusions drawn from this literature apply to children and adolescents-both healthy and those with cardiopulmonary disease-will be discussed. The few, recent, pertinent, pediatric studies will be reviewed in ...
The article focuses on the use of oxygen therapy in chronic obstructive pulmonary disease (COPD). Long term oxygen therapy (LTOT) is one of the few treatments which has significant survival benefits in patients with severe hypoxaemia. In less severe hypoxaemic patients the benefits of LTOT on survival are less clear. Other benefits of oxygen administration are generally accepted. Reduced ventilation, especially during exercise, helps to avoid dynamic hyperinflation and hence reduces symptoms and increases exercise tolerance in the majority of patients with COPD, even in patients with mild hypoxaemia ...
(HealthDay)-Sleep-disordered breathing (SDB) severity is associated with lower functional aerobic capacity (FAC) and increased blood pressure, according to a study published in the June 1 issue of The American Journal of ...
Caffeic acid has a high antioxidant potential. Studies show higher exercise tolerance significant reduction of the blood glucose.
the strength and integrity of coronary arteries.. Combat Fatigue & Lethargy- Goji is one of Asias historic adaptogens. Goji may help increase exercise tolerance, stamina and endurance. It also helps to eliminate fatigue, especially when recovering from illness.. Support Healthy Blood Pressure Levels- Nearly one in four adults has high blood pressure (hypertension). Uncontrolled high blood pressure can lead to stroke, heart attack, heart failure and kidney failure. A 1998 research study indicated that high blood pressure could be managed by the polysaccharides in goji.. Support Healthy Cholesterol Levels- Goji contains beta-sitosterol, which may help to lower cholesterol levels. Its antioxidants keep cholesterol from oxidizing and forming arterial plaques. The flavonoids in goji help to keep your arteries open and functioning smoothly.. Support & Balance Healthy Blood Sugar Levels- Goji has been used in China for those with adult-onset diabetes for many years. Its polysaccharides may help to ...
These results indicate that a 4 week supervised PR programme is equivalent to a 7 week supervised PR programme at comparable time points of 7 weeks and 6 months following completion of the programme. Importantly, the overall response to PR is similar to that documented in other trials.2,11 Interestingly, the 4 week group attained higher improvements in endurance walking times when compared with the 7 week group at the 7 week time point. There was also a trend for the 4 week group to attain greater improvements in all other outcome measures, although this did not reach statistical significance. A combination of hospital and home training appears to be as effective as supervised hospital based training. However, it is accepted that further study is needed to support this view.. At the 4 week time point the 4 week group largely matched the 7 week group with regard to improvements in both measures of exercise performance and health status. Patients in this trial could clearly not be blinded to the ...
Product name: Inderal. Active ingredient: Propranolol. Is used to: Generic Inderal is used for treating high blood pressure or atrial fibrillation. It is used in patients with angina to decrease angina frequency and increase exercise tolerance to decrease the risk of heart death in certain patients who have survived a heart attack to manage certain types of tremors, a heart condition called hypertrophic subaortic stenosis, or certain symptoms of pheochromocytoma (an adrenal tumor). It is also used to prevent migraine headaches.. Known As: Betachron / Inderal / InnoPran. Manufacturer: Cipla / Hab Pharma / Intas / Nicholas. Product Page: Go to store. Payment method: Visa / MasterCard. Delivery Time: 5-7 business days by Courier Service or 10-21 business days by Standard International Airmail. Bonuses: USPS - Fast Delivery Shipping 1-4 day USA Best quality drugs Fast Shipping USA Professional packaging 100% guarantee on delivery Best prices in the market Discounts for returning customers FDA ...
Product name: Inderal. Active substance: Propranolol. Is used to: Generic Inderal is used for treating high blood pressure or atrial fibrillation. It is used in patients with angina to decrease angina frequency and increase exercise tolerance to decrease the risk of heart death in certain patients who have survived a heart attack to manage certain types of tremors, a heart condition called hypertrophic subaortic stenosis, or certain symptoms of pheochromocytoma (an adrenal tumor). It is also used to prevent migraine headaches.. Also Known As: Betachron / Inderal / InnoPran. Manufacturer: Cipla / Hab Pharma / Intas / Nicholas. Purchase: Go to store. Payment method: Visa / Wiretransfer. Delivery Time: 5-7 business days by Courier Service or 10-21 business days by Standard International Airmail. Discount program: FREE pills! FREE shipping! Discounts! (up to 10%) & more.... ...
After a stroke or spinal cord injury, blood pools in the affected limbs, resulting in a decreased amount of blood returning to the heart. The force applied to the body through the hydrostatic pressure of water is similar to a compression stocking and increases the amount of blood returning to the heart, which improves blood pressure and increases exercise tolerance. ...
Pulmonary rehabilitation incorporates an individualised programme of physical training combined with targeted education for people who are functionally disabled by breathlessness. It aims to reduce symptoms and disability and to improve independence in people with lung disease.. At NNUH we have been running a pulmonary rehabilitation programme for 20 years. The programme is provided by a multi-professional team with involvement of the patient and family according to individual needs. Patients attend for a 2 hour session every week for eight weeks at the Willow Centre, Willowcroft Way, Cringleford and are taught exercises which can be undertaken in the home.. Although most of the evidence for pulmonary rehabilitation is for patients with chronic obstructive pulmonary disease (COPD), the benefits may also apply to patients with breathlessness from other respiratory diseases. Rehabilitation should be considered at all stages of disease progression when symptoms are present and not at a ...
Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. ...
The aging effect on microvascular integrity, marked by endothelial dysfunction and reduction in exercise tolerance, is a major cause of CVD (cardiovascular disease). Improved dietary habits, known to reduce morbidity and mortality, are also known to attenuate those aging effects. The present study investigated the effects of combined MD (Mediterranean diet) and exercise intervention on lower- and upper-limb cutaneous microvascular functions in an older healthy population. A total of 22 sedentary healthy participants (age, 55±4 years) underwent cardiopulmonary exercise tolerance test, and were assessed for their upper- and lower-limb vascular endothelial CVC (cutaneous vascular conductance) using LDF (laser Doppler fluximetry) with endothelium-dependent [ACh (acetylcholine chloride)] and -independent [SNP (sodium nitroprusside)] vasodilation. Participants were then randomized into two groups: MD and non-MD, and followed an 8-week intervention programme, which included discontinuous treadmill ...
AIMS: Cardiopulmonary exercise test (CPET) is used to evaluate patients with chronic heart failure (HF) usually by means of a personalized ramp exercise protocol. Our aim was to evaluate if exercise duration or ramp rate influences the results. METHODS AND RESULTS: Ninety HF patients were studied (peak V (O(2)): ,20 ml/min/kg, n=28, 15-20 ml/min/kg, n=39 and ,15 ml/min/kg, n=23). Each patient did four CPET studies. The initial study was used to separate the subjects into three groups, according to their exercise capacity. In the remaining studies, work-rate was increased at three different rates designed to have the subjects reach peak exercise in 5, 10 and 15 min from the start of the ramp increase in work-rate, respectively. The order was randomized. The work-rate applied for the total population averaged 22.7+/-8.0, 11.6+/-3.7, 7.5+/-2.9 W/min with effective loaded exercise duration of 5 min and 16 s+/-29 s, 9 min and 43 s+/-49 s and 14 min and 32 s+/-1 min and 12 s for the 5-, 10- and 15-min ...
There is evidence of the highest level to show that respiratory rehabilitation (RR) benefits COPD patients. The principal benefits are an increase in exercise tolerance for activities of daily living and an improvement in health-related quality of life.. RR is often criticized because the benefits of these programs are steadily lost after the patient has completed the intensive phase and loses contact with the rehabilitation team. As a result, guidelines insist on the need to implement new strategies that attempt to resolve this limitation.1,2. Telemedicine could, in theory, be a useful way of delivering RR maintenance programs to a larger COPD patient population, provided such an approach can be shown to maintain the benefits obtained from an initial intensive RR program.. Some programs have managed to maintain the initial benefits by prolonging the standard rehabilitation course for 6 months, instead of the usual 8 weeks. In a classic study conducted in outpatients, Troosters et al.3 found ...
Once you graduate from the pulmonary rehabilitation program you will have the opportunity to participate in a maintenance program. You can continue to use the gym and receive ongoing support from our expert staff. We want you to remain motivated and feeling your best.. If you have been diagnosed with chronic lung disease, request a referral from your physician for ProHealth Cares pulmonary rehabilitation program. For more information, call us at the following locations:. WAUKESHA ...
Pulmonary Rehabilitation. ATS guidelines recommend that the majority of patients with IPF be treated with pulmonary rehabilitation.11 Pulmonary rehabilitation programs include exercise for aerobic conditioning, strength, and flexibility; nutritional counseling; psychosocial support; and other educational interventions.11 Randomized controlled trials have shown that both 6MWT distance and patient-reported HRQOL outcomes are improved with pulmonary rehabilitation.36 It is important to note that 6MWT distance is itself associated with HRQOL in the setting of IPF and may be used as a prognostic factor.38 Importantly, the correlation between dyspnea, functional status, and depression has been found to be significant, suggesting that patients who can walk greater distances may have less dyspnea, and in turn, improved depressive symptoms.39. Two recent prospective trials have also demonstrated improved patient outcomes with pulmonary rehabilitation.39,40 A German study of 402 consecutive patients with ...
A total of 9,569 consecutive patients were included, of which 46.8% were women. Overall, exercise capacity and heart rate recovery were significantly associated with all-cause death. Exercise capacity, chest pain, and ST-segment deviations were significantly associated with subsequent MI. In general, the relationship between ETT variables and outcomes was similar between men and women, except for abnormal exercise capacity, which had a significantly stronger association with death in men (hazard ratio [HR], 2.89; 95% confidence interval [CI], 1.89-4.44), but not for women (HR, 0.99; 95% CI, 0.52-1.93). In contrast, chronotropic incompetence had a significantly stronger relationship with MI for women (HR, 2.79; 95% CI, 0.94-8.27) than for men (HR, 1.29; 95% CI, 0.74-2.20).. ...
Spiropalm 6MWT is a new device that incorporates a spirometer with a pulse oximeter and ventilation monitor. During a 6 Minute Walk Test, this compact and lightweight combination can be easily worn by a patient on a harness or a belt to collect real-time data. The resulting report provides clinicians with a cohesive and comprehensive means of evaluating 6-MWT results. Features include: Continuous measurement of SpO2 & HR throughout the walking/exercise period makes the clinician aware of desaturation that may have occured during the 6 minute walk but which was reversed by the end of the test. Measurement of Minute Ventilation (VE) and Breathing Pattern during walking. Measurement of Breathing Reserve (BR) and evaluation of Ventilatory Limitation. Evaluation of Dynamic Hyperinflation with Inspiratory Capacity (IC) measurement.. Product URL : Last Updated : 11/09/2012. Categories : Spirometers ...
Floyd Medical Center provides pulmonary rehabilitation for patients with respiratory illnesses, such as chronic obstructive pulmonary disease (COPD), control symptoms and improve day-to-day activities. Floyds outpatient pulmonary rehabilitation program uses exercise, behavior changes and education to help build a patients physical fitness. The goal is to return the patient to the highest possible level of activity. Our program can help you breathe better by focusing on:. ...
TY - JOUR. T1 - Exercise Testing. T2 - Who, When, and Why?. AU - Nelson, Nicole. AU - Asplund, Chad A.. PY - 2016/3/1. Y1 - 2016/3/1. N2 - There are different modalities of exercise testing that can provide valuable information to physicians about patient and athlete fitness and cardiopulmonary status. Cardiopulmonary exercise testing (CPX) is a form of exercise testing that measures ventilatory and gas exchange, heart rate, electrocardiogram, and blood pressures to provide detailed information on the cardiovascular, pulmonary, and muscular systems. This testing allows an accurate quantification of functional capacity/measure of exercise tolerance, diagnosis of cardiopulmonary disease, disease-progression monitoring or response to intervention, and the prescription of exercise and training. CPX directly measures inhaled and exhaled ventilator gases to determine the maximal oxygen uptake, which reflects the bodys maximal use of oxygen and defines the limits of the cardiopulmonary system. CPX is ...
Usually there is no cure for chronic lung issues such as COPD (Chronic Obstructive Pulmonary Disease), severe asthma, or cystic fibrosis. But there are ways to improve your quality of life through pulmonary rehabilitation.
The current study shows that low exercise capacity, age, type 2 diabetes, and hs-CRP levels are the most important determinants of cardiovascular autonomic function in patients with stable CAD with and without type 2 diabetes. HRT was also influenced by left ventricular systolic function. Autonomic function assessed by HRR, HR variability, or HRT predicted short-term cardiovascular end points in univariate analyses in CAD patients with type 2 diabetes, but not in their counterparts without type 2 diabetes. However, autonomic measures did not provide independent short-term prognostic information, even in the patients with type 2 diabetes, after adjusting for clinical, demographic, and echocardiographic risk variables, including a marker of low-grade inflammation, which remained as the independent prognostic marker.. Many studies have found an association between autonomic function and exercise capacity or physical fitness in the general population and in various patient groups, including cardiac ...
The Pulmonary Rehabilitation Program at UC Davis Health System has been certified by the American Association of Cardiovascular and Pulmonary Rehabilitation for leadership in improving health and quality of life for people with chronic obstructive pulmonary disease (COPD) and other lung diseases.
A study published in the European Journal of Preventive Cardiology10 sought to estimate a patients age based on performance during an exercise stress test. Over a 125,000 patients referred for exercise stress testing were included.. Estimated age was based on exercise capacity. After nearly nine years of follow-up, researchers discovered the patients estimated age based on their exercise stress test was a better predictor of mortality as compared to chronological age. The results held true for both men and women.. Researchers believe the key take-home messages were that exercise variables are powerful predictors of survival, and health care providers could consider using their physiological age as a way to motivate their patients to exercise more.11 A similar study12 evaluated 8,000 middle-aged and older adults and found adding physical activity of any intensity or duration cut their risk of early death.. The researchers believe the findings highlight the importance of movement, regardless of ...
There are lots of people today who are not satisfied with their height. Many of them suffer because they have experienced that height could be a hindrance in getting a great job, promotions and attention. There are individuals in search to find a great height increase exercise to gain a...
Learn about symptoms and signs associated with an inability to exercise (exercise intolerance). Associated symptoms and signs can include shortness of breath, weakness, and muscle pain. Pinpoint your symptoms and signs with MedicineNets Symptom Checker.
Pulmonary rehabilitation is accepted as an essential strategy for the management of respiratory disease. However, there is wide variation in models of service delivery, and evidence to understand which elements are most effective is less clear. This analysis outlines key elements of an occupational therapy-led pulmonary rehabilitation programme.. Critical reflection on practice ...
A pulmonary rehabilitation program is designed to meet the needs of the individual patient, depending upon the specific lung problem or disease. Active involvement of the patient and family is vital to the success of the program.. The goal of pulmonary rehabilitation is to help patients return to the highest level of function and independence possible, while improving the overall quality of life--physically, emotionally, and socially. These goals are often met by:. ...
This study is investigating the effects of udenafil on symptom, exercise capacity and hemodynamic status in patients with mild pulmonary hypertension.
We recently came across an article that reported on how patients with Cystic Fibrosis (CF) have less exercise capacity than their peers, even though their
Inovas comprehensive Pulmonary Rehabilitation Program is a medically supervised, therapeutic treatment program designed to help patients with pulmonary disease improve their quality of life and exercise capacity.
TY - GEN. T1 - Simple functional exercises can assist with increasing range of moment in the forelimb of dogs. AU - Kopec, Nadia L.. AU - Tabor, Gillian. AU - Williams, Jane. PY - 2018/1. Y1 - 2018/1. M3 - Article in lay press/specialist publication. VL - 2018. SP - 16. EP - 19. JO - Animal Therapy Magazine. JF - Animal Therapy Magazine. ER - ...
Dr. Daniel Tsoi, Auburn Cardiologist, puts Medically Speaking Radio to the test by having Dr. Vaughan perform an exercise treadmill test. In addition to the exercise treadmill test, we also discuss other ways that a Cardiologist evaluates a patient for heart disease and the resulting treatments.. ...
... decreased exercise tolerance and exertional chest pain may occur. On physical examination, characteristic findings are the ... In people with stable OHS, the most important treatment is weight loss-by diet, through exercise, with medication, or sometimes ...
Helps improve exercise tolerance, by allowing the user to exercise longer. Helps increase stamina throughout day-to-day ...
"Submission to the Church of England's Listening Exercise on Human Sexuality". The Royal College of Psychiatrists. Retrieved 13 ... p. 2. ISBN 0-226-72988-5. "The five most improved places for gay tolerance". The Independent. London. 17 September 2008. ... ISBN 0-8057-9714-9 Boswell, John (1980), Christianity, Social Tolerance, and Homosexuality: Gay People in Western Europe from ... Robinson, B. A. (2010). "Divergent beliefs about the nature of homosexuality". Religious Retrieved 12 September ...
"All groups have to exercise tolerance and restraint. Christians cannot expect this to be a Christian society, Muslims cannot ...
"Human tolerance and physiological responses to exercise while breathing oxygen at 2.0 ATA". Aviat Space Environ Med. 66 (4): ... September 1977). "Human tolerance to He, Ne, and N2 at respiratory gas densities equivalent to He-O2 breathing at depths to ... Lambertsen CJ (1988). "Extension of oxygen tolerance in man: philosophy and significance". Exp. Lung Res. 14 Suppl: 1035-58. ... Research in tolerance and toxicity of respiratory gasses and development of diving procedures and equipment. ...
The development of tolerance also may vary among individuals. Patients with renal abnormalities must exercise caution when ...
Reduced exercise tolerance: symptoms also caused by decreased systemic (oxygenated blood to the rest of the body) flow. Just as ... For symptoms such as loud mitral S1, pulmonary S2, mid-diastolic murmur, fatigue, reduced exercise tolerance, weight gain, ... this causes tiredness and hence a reduced exercise tolerance. Weight gain: this is commonly found in patients with large ASD ... To ensure good health, routine doctors visits, diet, weight loss, doctor-approved exercise, and use of antibiotics in dental ...
An association with exercise intolerance has been reported. Swain R, Bapna JS (January 1986). "Impairment of exercise tolerance ...
Barwood, Martin J.; Newton, Phillip S.; Tipton, Michael J. (2009). "Ventilated Vest and Tolerance for Intermittent Exercise in ... 2012). "Skin Wettedness". Encyclopedia of Exercise Medicine in Health and Disease. p. 790. doi:10.1007/978-3-540-29807-6_3041. ... People might adapt to seasonal heat by becoming more nocturnal, doing physical activity and even conducting business at night. ... Exercise. 32 (9 Suppl): S498-504. CiteSeerX doi:10.1097/00005768-200009001-00009. PMID 10993420.. ...
Szabo, A. (2003) The acute effects of humor and exercise on mood and anxiety. Journal of Leisure Research. (35)2, 152-162. http ... Humor's effect on pain tolerance is another point of interest within humor research. Hypotheses for this research include the ... Weaver, J., & Zillmann, D. (1994). Effect of humor and tragedy on discomfort tolerance. Perceptual and Motor Skills, 78, 632- ... Weisenberg, M., Tepper, L, & Schwarzwald, J. (1995). Humor as a cognitive technique for increasing pain tolerance. Pain, 63, ...
... and exercise-heat tolerance". Exercise and Sport Sciences Reviews. 35 (3): 135-40. doi:10.1097/jes.0b013e3180a02cc1. PMID ... Non-regular caffeine users have the least caffeine tolerance for sleep disruption. Some coffee drinkers develop tolerance to ... While this effect is not present during exercise-to-exhaustion exercise, performance is significantly enhanced. This is ... Tolerance varies for daily, regular caffeine users and high caffeine users. High doses of caffeine (750 to 1200 mg/day spread ...
These changes lead to increased strength and tolerance for exercise. Sex differences are apparent as males tend to develop " ... 1998). "Developmental changes in energy expenditure and physical activity in children: Evidence for a decline in physical ... In less restrictive cultures, there is more tolerance for displays of adolescent sexuality, or of the interaction between males ... For example, girls tend to reduce their physical activity in preadolescence and may receive inadequate nutrition from diets ...
"Does creatine supplementation hinder exercise heat tolerance or hydration status? A systematic review with meta-analyses". ... A clinical study has shown that the intake of pure, high-quality creatine alone, or in combination with exercise, may reduce ... August 2018). "ISSN exercise & sports nutrition review update: research & recommendations". Journal of the International ... Cooper R, Naclerio F, Allgrove J, Jimenez A (July 2012). "Creatine supplementation with specific view to exercise/sports ...
Symptoms in puppies are generally a failure to grow and a reduced tolerance for exercise. Active treatment is effective in ...
No interference with exercise of personnel tenets or practices; prohibition of threatening, abusive, exploitative, coercive ... Disciplinary Practices: Treat all personnel with dignity and respect; zero tolerance of corporal punishment, mental or physical ...
Symptoms are typically decreased exercise tolerance, easy fatigability, palpitations, and syncope.[citation needed] ... shortness of breath with minimal exercise), congestive heart failure, or cerebrovascular accident (stroke). They may be noted ...
Dyspnea (painful breathing or difficulty breathing) is commonly seen, and tolerance for exercise may be lowered. Rapid ...
The exercise of power conferred by an offer by performance of some act. The act of a person to whom something is offered of ... The definition overlaps with toleration, but acceptance and tolerance are not synonyms. Acceptance - "An express act or ... which can be derived from a lack of eating or exercise. They don't sleep well, their immune systems sputter, and they even tend ...
Supporters said that the publication of the cartoons was a legitimate exercise in free speech: regardless of the content of the ... The Danish tradition of relatively high tolerance for freedom of speech became the focus of some attention. The controversy ... tolerance and offence have backfired on the West. Michael Neumann wrote:[193] ... ignited a debate about the limits of freedom of expression in all societies, religious tolerance and the relationship of Muslim ...
The studies completed during Apollo, although less than optimal, left no doubt that a decrement in exercise tolerance occurred ... A significant decrement in cardiac stroke volume was associated with diminished exercise tolerance. It was not clear whether ... The astronauts' performance on the lunar surface provided no reason to believe that any serious exercise tolerance decrement ... Highly refined exercise protocols and robust exercise equipment and methods to monitor functional capacity are mandatory for ...
During pregnancy, doctors recommend light exercise. Doctors state that exercise can help the comfort of the mother and the well ... For mothers, impaired glucose tolerance and hyperlipidemia are more common among obese mothers. There are many options ... Moderate forms of exercise, such as walking, can lead to healthy weight loss. Some people who are obese turn to gastric bypass ... "The Pregnant Mother: Exercise During Pregnancy". Ohio State University Medical Center. 2009. Archived from the original on 2009 ...
... taken 30 minutes prior to exercise has been shown to help improve exercise tolerance including a lower heart rate and lower ... Vissing, John; Haller, Ronald G. (2003-12-25). "The Effect of Oral Sucrose on Exercise Tolerance in Patients with McArdle's ... This is characterized by the patient's better tolerance for aerobic exercise such as walking and cycling after approximately 10 ... Supervised exercise programs have been shown in small studies to improve exercise capacity by several measures. Oral sucrose ...
... decreased exercise tolerance, and episodes of syncope. 21% of children and 30% of adults have evidence of pulmonary ... While it has been historically recommended that people with sickle cell disease avoid exercise, regular exercise may benefit ... This also contributes to pulmonary hypertension, decreased exercise capacity, and arrhythmias. Chronic kidney failure due to ...
In heart failure patients, fosinopril increases exercise tolerance and lowers the frequency of events associated with worsening ... Fosinopril attenuates clinical deterioration and improves exercise tolerance in patients with heart failure. Fosinopril ...
Fatigue and reduced exercise tolerance are prominent symptoms of both conditions, and dysautonomia may underlie both conditions ... such as endurance training or graded exercise therapy, can relieve symptoms for some patients.[5] Aerobic exercise performed ... In up to one third of people with POTS,[1] fainting occurs in response to postural changes or exercise.[5] Migraine-like ... Prolonged physical inactivity can worsen the symptoms of POTS.[5] Techniques that increase a person's capacity for exercise, ...
American Institute for Cancer Research (2007). Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global ... Lack of secular tolerance and caste politics has also given birth to Hindu extremist vigilante cow protection groups. Conflicts ...
Exercise increases pain thresholds and pain tolerance. This effect, called exercise-induced analgesia, is known to occur in ... After such exercise, the muscle adapts rapidly to prevent muscle damage, and thereby soreness, if the exercise is repeated.[1][ ... Isometric (static) exercise causes much less soreness, and concentric (shortening) exercise causes none.[2]:63 ... Armstrong, RB (August 1990). "Initial events in exercise-induced muscular injury". Medicine & Science in Sports & Exercise. 22 ...
Such impairments include fatigue, weakness, hypertonicity, low exercise tolerance, impaired balance, ataxia and tremor. ...
In those with impaired glucose tolerance, diet and exercise either alone or in combination with metformin or acarbose may ... A proper diet and exercise are the foundations of diabetic care,[23] with a greater amount of exercise yielding better results. ... Impaired glucose tolerance. ≥ 7.8. ≥ 140. , 7.0. , 126. 42-46. 6.0-6.4 Diabetes mellitus. ≥ 11.1. ≥ 200. ≥ 7.0. ≥ 126. ≥ 48. ≥ ... The benefit of exercise occurs regardless of the person's initial weight or subsequent weight loss.[72] High levels of physical ...
... and so has a built-in slight direction-error tolerance). Photons that do not arrive in temporal "pairs" (i.e. within a timing- ... is that PET provides no timing information about muscle activation because it has to be measured after the exercise is ...
The dancing exercise is a "thank you" for the healing and tribute to the spiritual greater beings. The dance is accompanied by ... and develop tolerance and empathy.[18] Group sessions that emphasize cooperation and cohesion can be effective in working with ... feel emotionally relieved because the priest has announced them clean and subjected them to a rigorous dancing exercise. ...
Research Quarterly for Exercise and Sport. 63 (3): 292-301. doi:10.1080/02701367.1992.10608745. PMID 1513960.. ... Communities that participate in observational learning promote tolerance and mutual understand of those coming from different ...
Exercise and disease management 2nd ed. Boca Raton: CRC Press. : 25. ISBN 978-1-4398-2759-8.. 引文格式1維護:冗餘文本 (link) ... 糖耐量受損(英語:Impaired glucose tolerance). ≥7.8(≥140). ,7.0(,126). 6.0-6.4. ...
... she wrote to all of her children at least once a week and believed herself entitled to exercise authority over her children ... Freedom of religion was granted only in the Declaration of Tolerance issued by Joseph immediately after Maria Theresa´s death.[ ...
Glucose tolerance testing (GTT) instead of fasting glucose can increase diagnosis of impaired glucose tolerance and frank ... the role of exercise and diet. Seminars in Reproductive Medicine (Review). 2009, 27 (4): 306-15. PMID 19530064. doi:10.1055/s- ... Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta- ... 2-Hour oral glucose tolerance test (GTT) in women with risk factors (obesity, family history, history of gestational diabetes)[ ...
Most fled to Poland, as it had a reputation for religious tolerance unparalleled during this era. This religious tolerance may ... and when these attempts failed they were ever more and more restricted in the exercise of their civil rights. Soon they were ...
"Exercise or exercise and diet for preventing type 2 diabetes mellitus". Cochrane Database Syst Rev (3): CD003054. doi:10.1002/ ... "Lifestyle interventions reduced the long-term risk of diabetes in adults with impaired glucose tolerance". Evid Based Med 13 (6 ... O'Gorman, DJ; Krook, A (2011 Sep). "Exercise and the treatment of diabetes and obesity". The Medical clinics of North America ... 33.0 33.1 33.2 Zanuso S, Jimenez A, Pugliese G, Corigliano G, Balducci S (March 2010). "Exercise for the management of type 2 ...
Stress - exercise, surgery, general stress. *Medication induced - corticosteroids (for example, prednisone, β-agonists, lithium ... exercise, environment, and exposure to allergens.[15] Eosinophilia is never a normal lab finding. Efforts should always be made ...
... s are more likely to exercise regularly than heterosexual women, and lesbians do not generally exercise for aesthetic ... Vincent Millay and social host Mabel Dodge were known for their affairs with women and promotion of tolerance of homosexuality. ... The novel included a foreword by Havelock Ellis and was intended to be a call for tolerance for inverts by publicizing their ... which promoted tolerance for homosexuals in Germany, welcomed lesbian participation, and a surge of lesbian-themed writing and ...
September 13, 2010). Ascorbate-Glutathione Pathway and Stress Tolerance in Plants. Springer. p. 324. ISBN 978-9-048-19403-2. . ... function of the immune system during and after extreme physical exercise (ID 144), non-haem iron absorption (ID 132, 147), ...
Ontario Consultants on Religious Tolerance. Retrieved 27 December 2017.. "Religious Landscape Study". Pew Research Center's ... "Imitate Jehovah-Exercise Justice and Righteousness". The Watchtower. August 1, 1998. p. 16.. ...
Nieder C, Milas L, Ang KK (2000). "Tissue tolerance to reirradiation". Semin Radiat Oncol. 10 (3): 200-9. doi:10.1053/srao. ... 1954 Totskoye nuclear exercise. *Bikini Atoll. *Hanford Site. *Rocky Flats Plant. *1945 Atomic bombings of Hiroshima and ... The salivary glands and tear glands have a radiation tolerance of about 30 Gy in 2 Gy fractions, a dose which is exceeded by ...
... disease tolerance, pest tolerance, nutritional value, and numerous other traits.[citation needed] ... "A systematic review of dietary, nutritional, and physical activity interventions for the prevention of prostate cancer ... and tolerance/resistance to various environmental pressures, including disease.[43][44] However, these breeding efforts have ...
... decrease in heart rate both at rest and during exercise, resulting in decreased exercise tolerance.[39] ... "Infra-stellate upper thoracic sympathectomy results in a relative bradycardia during exercise, irrespective of the operated ...
Muriel R. Gillick, a baby boomer, accuses her contemporaries of believing that by proper exercise and diet they can avoid the ... "little tolerance for older persons and very few reservations about harboring negative attitudes" about them.[113] ... One exercise was to lay out 3 sets of 5 slips of paper. On set #1, write your 5 most enjoyed activities; on set #2, write your ...
Exercise. Main article: Exercise. Physical exercise enhances or maintains physical fitness and overall health and wellness. It ... Stress management is the application of methods to either reduce stress or increase tolerance to stress. Relaxation techniques ... "4 Types of Exercise". Go4Life, National Institute on Aging, US National Institutes of Health. 15 May 2014.. ... According to the National Institutes of Health, there are four types of exercise: endurance, strength, flexibility, and balance ...
Exercise, sport and physical activity. Physical activity can influence people's psychological[193] and physical health.[194] ... tolerance (i.e., short-term benefits wearing off with time), and withdrawal syndrome; additionally, individuals with PTSD (even ... They recommend a discussion with a doctor before starting an exercise program.[195] ... The U.S. National Center for PTSD recommends moderate exercise as a way to distract from disturbing emotions, build self-esteem ...
Tolerance may also develop over time due compensatory response of the body, as well as depletion of -SH groups of glutathione ... physical activity, and control for other risk factors including diabetes, obesity, and hypertension. Pharmacological therapies ...
In 1916, The Literary Digest embarked on a national survey (partly as a circulation-raising exercise) and correctly predicted ...
live fire exercise or LFX: Any exercise that simulates a realistic scenario for the use of specific equipment. In the popular ... This refers to parts that are designed and manufactured such that they have a relatively tight-tolerances and high level of ...
... dyspnoea and exercise tolerance in COPD". Eur Respir J 23 (6): 832-40. doi:10.1183/09031936.04.00116004. பப்மெட்:15218994. http ... Celli BR, Cote CG, Marin JM, et al. (March 2004). "The body-mass index, airflow obstruction, dyspnea, and exercise capacity ... 64.0 64.1 O'Donnell DE (2006). "Hyperinflation, Dyspnea, and Exercise Intolerance in Chronic Obstructive Pulmonary Disease". ... Exercise capacity) பயன்படுகிறது. இது எஃப்ஈவி யை பொறுத்து பூஜ்யத்திலிருந்து பத்து வரை மதிப்பெண் கொடுக்கிறது 1, உடல்நிறை ...
The Third Exercise: Penetrating the Two Cosmic Extremes:. The principles of this exercise, as stated in Falun Gong, are: "This ... Ontaria Consultants on Religious Tolerance. "INTRODUCTION TO FALUN GONG & FALUN DAFA Its terminology, symbol, texts, beliefs, ... The Fourth Exercise: Falun Heavenly Circuit:. Falun Gong says the fourth exercise is "intermediate-level". "On the basis of the ... This exercise is a tranquil standing meditation composed of four standing stances. The book Falun Gong states that the exercise ...
... it is important that the individual be prescribed and regularly engage in a supplementary home exercise program that ... Tolerance/intolerance. *Weight. *Beverage-specific *Beer: Potomania. *Red wine: Red wine headache ... physical therapy should include an exercise program addressing five components: static balance, dynamic balance, trunk-limb ...
Rare cases of pulmonary hypertension and cardiac valvular disease have been reported.[12] Tolerance usually occurs; however, ... Phentermine is used for a short period of time to promote weight loss, if exercise and calorie reduction are not sufficient, ... is a medication used together with diet and exercise to treat obesity.[3] It is taken by mouth for up to a few weeks.[3] After ... and in addition to exercise and calorie reduction.[4][12]. Phentermine is approved for up to 12 weeks of use and most weight ...
"Aerobic physical exercise for adult patients with haematological malignancies". The Cochrane Database of Systematic Reviews. 1 ... asparaginase (better tolerance in people in pediatric care). *daunorubicin (used in Adult ALL) ...
... identity tolerance, (4) identity acceptance, (5) identity pride, and (6) identity synthesis.[42] Fassinger's model of gay and ...
Webb JT; Olson RM; Krutz RW; Dixon G; Barnicott PT (1989). "Human tolerance to 100% oxygen at 9.5 psia during five daily ... Available studies support a performance boost from oxygen enriched mixtures only if it is breathed during aerobic exercise.[106 ...
Creighton, Mandell (1906), Persecution and Tolerance: Hulsean Lectures, University of Cambridge, 1893-94, London, New York and ... As Creighton was popular with students, he was looked upon as someone who would exercise that leadership. He proceeded to do so ... Among his addresses were the Hulsean Lectures at Cambridge in the winter of 1893-94 on "Persecution and Tolerance", the 1895 ... Walking gave him many opportunities to exercise his abiding curiosity in the local botany and architecture. The habit was to ...
Factors limiting exercise tolerance in chronic lung diseases.. Vogiatzis I1, Zakynthinos S. ... As exercise intolerance in COPD is recognized as being multifactorial, the impacts of the following factors on patients ... A great deal of emphasis is given, however, to causes of exercise intolerance in COPD mainly because of the plethora of ... The major limitation to exercise performance in patients with chronic lung diseases is an issue of great importance since ...
Home -, Community -, Mailing Lists -, Oracle-L -, Improved exercise performance and tolerance Improved exercise performance and ... tolerance. From. : laurence perkins ,, Date. : Sat, 29 Jul 2006 14:11:39 +0700. Message-ID. : , ...
Oral taurine improves critical power and severe-intensity exercise tolerance.. Waldron M1,2, Patterson SD3, Jeffries O4. ... Oral taurine can be taken prior to exercise to enhance endurance performance. ...
Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema. Br Med J (Clin Res Ed) 1981; 283 :878 ... The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 ... Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema.. Br Med J (Clin Res Ed) 1981; 283 doi: https://doi. ... of carboxyhaemoglobin frequently found in bronchitic patients who smoke may reduce their tolerance of everyday exercise, ...
Exercise for Desaturation Tests), including what the test is, how to prepare for the test, and whats done during the test. ... Answers to common questions and concerns regarding Exercise Tolerance Tests ( ... Exercise Tolerance Test and Exercise for Desaturation Test. What is Exercise Tolerance testing?. The exercise tolerance test ... Exercise Tolerance Test. If you are doing the exercise tolerance test, you will be asked to ride a stationary bicycle. You will ...
Effect of attitudes and beliefs on exercise tolerance in chronic bronchitis. Br Med J (Clin Res Ed) 1983; 286 :171 ... Subjective perception of exertion was most closely correlated with exercise tolerance. The distance walked in a 12-minute ... In 50 patients with chronic bronchitis the relation was assessed between exercise tolerance and pulmonary function and ... Ventilatory capacity was significantly correlated with but a poor predictor of exercise tolerance. ...
What is an Exercise Tolerance Test?. An exercise tolerance test lets the physician see how well your heart functions when it ... An exercise tolerance test is usually safe. There is a small amount of risk because the heart is being stressed. These risks ... When the exercise portion of the test is over, your EKG and blood pressure will continue to be monitored for several minutes. ... You will exercise on a treadmill while your EKG and blood pressure are monitored. ...
Exercise tolerance testing (ETT) was introduced in the 1940s and has been the focus of many investigations (Detry and Fox, 1996 ... Exercise tolerance testing (ETT) was introduced in the 1940s and has been the focus of many investigations (Detry and Fox, 1996 ...
... heavy drinkers in high exercise tolerance categories had no higher blood pressure than nondrinkers in low exercise tolerance ... Exercise tolerance was determined by maximal treadmill exercise testing and was categorized into six age-specific by sex- ... Exercise tolerance and alcohol intake. Blood pressure relation.. G H Hartung, H W Kohl, S N Blair, S J Lawrence, R B Harrist ... Exercise tolerance and alcohol intake. Blood pressure relation.. G H Hartung, H W Kohl, S N Blair, S J Lawrence and R B Harrist ...
Exercise tolerance and cardiorespiratory adjustments at peak work capacity (PWC) were determined in 20 patients with cystic ... Exercise tolerance and cardiorespiratory adjustments at peak work capacity in cystic fibrosis Am Rev Respir Dis. 1982 Aug;126(2 ... there are decreases in exercise tolerance and cardiorespiratory reserves, exercise-induced ventilation-perfusion abnormalities ... Exercise tolerance and cardiorespiratory adjustments at peak work capacity (PWC) were determined in 20 patients with cystic ...
Oxidative Capacity and Exercise Tolerance in Ambulatory SMA. Official Title Evaluation of Oxidative Capacity and Exercise ... Oxidative Capacity and Exercise Tolerance in Ambulatory SMA. The safety and scientific validity of this study is the ... Participants will undergo an exercise stress test performed by a clinical exercise physiologist using an electronically-braked ... The presence of any contraindication to exercise according the ACSM criteria.. Patients with and without Spinraza treatment are ...
An Evaluation of Exercise Tolerance in Asthmatic Patients. The safety and scientific validity of this study is the ...
"Elon Musk: Balancing Purpose and Risk; Risk Tolerance Exercise." Harvard Business School Spreadsheet Supplement 819-704, June ... Elon Musk: Balancing Purpose and Risk; Risk Tolerance Exercise. by Shikhar Ghosh ...
... fats release proteins into the bloodstream that improves glucose tolerance. ... Exercise training causes dramatic changes to fat, where these trained ... Exercise and Fitness. Exercise is about revamping your lifestyle, not just weight loss. Exercise to get healthy - that way, ... Not only did exercise-stimulated TGF-beta 2 improve glucose tolerance, treating obese mice with TGF beta 2 lowered blood lipid ...
Researchers wanted to learn if patients following a pre-surgical program of weight management and exercise tolerance can have ... Exercise and Fitness. Exercise is about revamping your lifestyle, not just weight loss. Exercise to get healthy that way, you ... Exercise To Gain Weight. Are you underweight and want to know how to gain weight? Exercise or workouts can help you gain weight ... A pre-surgical program of weight management and exercise tolerance can have greater success from the first surgery for ventral ...
Aortic Distensibility Independently Affects Exercise Tolerance in Patients With Dilated Cardiomyopathy. Stefano Bonapace, ... Aortic Distensibility Independently Affects Exercise Tolerance in Patients With Dilated Cardiomyopathy. Stefano Bonapace, ... Aortic Distensibility Independently Affects Exercise Tolerance in Patients With Dilated Cardiomyopathy. Stefano Bonapace, ...
tolerance time. The extent to which a therapeutic strategy improves exercise tolerance in a subject with impaired physiological ... Costes F, Agresti A, Court-Fortune I, et al. Noninvasive ventilation during exercise training improves exercise tolerance in ... Puente-Maestu L, Santa Cruz A, Vargas T, et al. Effects of training on the tolerance to high-intensity exercise in patients ... But, of course, determining the exercise tolerance time at a work rate which is double that of the critical power is quite ...
Winter Blues? Study Suggests Exercise Builds both Fitness and Cold Tolerance. By Daniel Cervone ... and whether exercise could improve the mouses tolerance.. "It is now recognized that white fat can become browner - sometimes ... Mice that were able to exercise daily leading up to the cold test had a higher body temperature and lost less weight in their ... "It appears that simply exercise training muscle may help mice better respond to the cold by contributing to more efficient ...
The aim of this study is to test our hypothesis that normal exercise tolerance differs according to gender and to identify ... Cardiac mechanisms underlying normal exercise tolerance: gender impact. Lindqvist, Per Umeå University, Faculty of Medicine, ... Exercise echocardiography, Gender, Filling pressure, Speckle tracking echocardiography National Category Physiology Sport and ... These native normal differences between genders may explain the known vulnerability of women to endurance exercise compared to ...
How the Colonies in America Moved from "Tolerance" to "Free Exercise" of Religion Justin Taylor , September 9, 2016 ... This move-from "tolerance" to "free exercise"-set off a back-and-forth that lasted over a decade. Formal disestablishment came ... Tolerance based solely on the governments benevolence lasts only as long, and as far, as the benevolence does. Dont blink; ... George Mason had drafted a key line: "all Men should enjoy the fullest Toleration in the Exercise of Religion, according to the ...
Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ... Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ... Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ... Tolerance to the Bronchoprotective Effect of Salmeterol in Adolescents With Exercise-induced Asthma Using Concurrent Inhaled ...
increased their exercise tolerance (bicycle exercise test) by 23% watts following 1-month EAA supplementation. In placebo ... The benefit of EAAs for exercise tolerance was confirmed by two investigations performed in ambulatory CHF patients. In the ... EAAs and Exercise in CHF Subjects (Table 2). Three investigations reported that it is possible to increase exercise capacity of ... Essential Amino Acids and Exercise Tolerance in Elderly Muscle-Depleted Subjects with Chronic Diseases: A Rehabilitation ...
Provoked exercise desaturation in patent foramen ovale and impact of percutaneous closure.  Devendra, Ganesh P; Krasuski, ... Magnitude of spinal muscle damage is not statistically associated with exercise-induced low back pain intensity.  Arpan, I; ... OBJECTIVES: This study was designed to assess the prevalence of provoked exercise desaturation (PED) in patients with patent ...
Our purpose was to determine if these ergogenic aids are also effective to improve exercise tolerance in age-matched sedentary ... Our purpose was to determine if these ergogenic aids are also effective to improve exercise tolerance in age-matched sedentary ... LCHO did not benefit exercise tolerance compared to PLA and was less effective (p,0.05) compared to CAF+LCHO for all ... LCHO did not benefit exercise tolerance compared to PLA and was less effective (p p p ...
... exercise tolerance. The relationship of sociodemographic factors to social support was examined, as well as the role of social ... Specifically, older individuals had poorer exercise tolerance, whereas those with more income had better exercise tolerance. ... Exercise Tolerance*. Follow-Up Studies. Heart Diseases / epidemiology, physiopathology*, rehabilitation*. Humans. Male. Middle ... An exercise tolerance test was completed upon entry into cardiac rehabilitation, after 14 weeks, and after 9 months. RESULTS: ...
Exercise tolerance test demonstrating dynamic Brugada ECG pattern. Stage 1 of Bruce protocol exercise (left) and post-exercise ... Aim We determined the diagnostic yield of exercise tolerance testing (ETT) in investigation of inherited cardiac conditions ... 50 Diagnostic role of exercise tolerance testing in familial premature sudden cardiac death ... 50 Diagnostic role of exercise tolerance testing in familial premature sudden cardiac death ...
Experimental: Exercise-immediate Breakfast followed by exercise and an immediate OGTT. Behavioral: Exercise Exercise at 55% of ... Breakfast followed by exercise and a delayed (1 h) OGTT.. Behavioral: Exercise Exercise at 55% of maximum power output for 30 ... Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.. The safety and scientific validity of ... Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.. ...
Keywords: 6-minute stepper test, 6-minute walk test, exercise tolerance, pulmonary rehabilitation, cardiopulmonary exercise ... The results of this study show that the 6MST is a valid test to evaluate exercise tolerance in COPD patients. The use of this ... Exercise tolerance testing is an integral part of the pulmonary rehabilitation (PR) management of patients with chronic ... and cardiopulmonary exercise testing (CPET) in a cohort of COPD patients.Methods: Ninety-one COPD patients managed by ...
Changes in exercise parameters, measured at rest, isotime and peak exercise on days 0, 21 and 42 from pretreatment exercise ... Three main time-points were used for evaluation of exercise parameters, i.e. pre-exercise rest, isotime and peak exercise. " ... dyspnoea and exercise tolerance in COPD. D.E. ODonnell, T. Flüge, F. Gerken, A. Hamilton, K. Webb, B. Aguilaniu, B. Make, H. ... which examined the effects of ipratropium on exercise tolerance in COPD 6, acute reductions in IC from rest to end of exercise ...
  • The extent to which a therapeutic strategy improves exercise tolerance in a subject with impaired physiological function is considered to be a reflection of both the utility of the intervention and of its effectiveness. (
  • CONCLUSION: In COPD patients with low PEF, pursed-lip breathing reduces dynamic hyperinflation and improves exercise tolerance, breathing pattern and arterial oxygenation at submaximal intensity exercise. (
  • Ferracini Cabral L, Elia DC, De Sousa Marins D, Araujo Zin W, Silva Guimarães F. Pursed lip breathing improves exercise tolerance in COPD: a randomized crossover study. (
  • 3, 4-Dihydroxycinnamic Acid Attenuates the Fatigue and Improves Exercise Tolerance in Rats. (
  • Treatment with Orkambi significantly improves exercise tolerance in adult cystic fibrosis patients with severe disease as early as 4 weeks after treatment - as shown by results of the six-minute walk test (6MWT), a study found. (
  • Objectives: We tested the hypothesis that intravenous iron improves exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure (CHF) and iron deficiency. (
  • If you are doing the exercise for desaturation test, you will be asked to walk on a treadmill at a comfortable pace for a maximum of 6 minutes per exercise period. (
  • You will exercise on a treadmill while your EKG and blood pressure are monitored. (
  • Exercise tolerance was determined by maximal treadmill exercise testing and was categorized into six age-specific by sex-specific levels. (
  • Exercise tolerance was assessed by treadmill time, and changes in diastolic function were quantified by transmitral flow (E/A ratio). (
  • The primary endpoint was total exercise duration in the modified Bruce treadmill test at the 6-month follow-up. (
  • Conclusion The total exercise duration in the modified Bruce treadmill test at the 6-month follow-up did not differ significantly in patients treated with CSWT compared with optimal medical therapy alone. (
  • VO2 max (maximal oxygen consumption during maximal physical exercise and is measured by exercise tolerance test or Bruce test with walking on treadmill) and diastolic function of 8-scssion group. (
  • An exercise tolerance test measures your heart's rhythm and electrical activity and your blood pressure during exercise, and takes place on a treadmill within the clinic. (
  • You will then be asked to exercise on a treadmill or on an exercise bike. (
  • The exercise starts at a very easy pace, and is gradually made more strenuous by increasing the speed and incline of the treadmill, or by putting some resistance on the bike wheel. (
  • Our pediatric exercise laboratory uses a stationary bicycle or a treadmill. (
  • During an exercise tolerance (stress) test, the person walks at an increasingly rapid pace on a treadmill. (
  • A great deal of emphasis is given, however, to causes of exercise intolerance in COPD mainly because of the plethora of research findings that have been published in this area and also because exercise intolerance in COPD has been used as a model for understanding the interactions of different pathophysiologic mechanisms in exercise limitation. (
  • Exercise intolerance remains problematic in subjects with chronic heart failure (CHF) and/or chronic obstructive pulmonary disease (COPD). (
  • The 3 studies consistently showed that elderly CHF and COPD improved exercise intolerance after 1-3 months of EAA supplementation (8 g/d). (
  • EAA mechanisms explaining improved exercise intolerance could be increases in muscle aerobic metabolism, mass and function, and improvement of tissue insulin sensitivity (the latter only for the CHF population). (
  • Early onsets of fatigue and/or dyspnea are the symptoms responsible for this exercise intolerance. (
  • Exercise intolerance, accentuated in the elderly because of aging body changes, negatively impacts both functional and life prognosis. (
  • In CHF, it is exercise intolerance and not heart function which is the most important prognostic factor [ 5 ], which furthermore is more accurate than hemodynamic/ventilator profiles at predicting outcomes [ 5 ]. (
  • Therefore, improved exercise intolerance of CHF/COPD patients is a key for maintaining the subjects' autonomy and quality of life as well as for increasing survival. (
  • If I don't take the time off to recover I get the severe exercise intolerance. (
  • In summary, CK-2127107 increases exercise performance in this heart failure model, suggesting that modulation of skeletal muscle function by a fast skeletal troponin activator may be a useful therapeutic in heart failure-associated exercise intolerance. (
  • The impact of progressive dyspnea, fatigue, exercise intolerance, and recurrent exacerbations in patients with COPD can be devastating to their quality of life. (
  • Dyspnea and exercise intolerance are the two most common complaints from patients with COPD, who also have to cope with exacerbations and remissions. (
  • The main causes of exercise intolerance are angina pectoris due to myocardial ischemia, dyspnea in congestive heart failure due to loss of muscle mass, and muscular dysfunction or valvular disease. (
  • Besides the heart, peripheral arterial occlusive disease is a major cause for exercise intolerance. (
  • Furthermore, the degree of exercise intolerance in pALS might correlate with the reduction in the number and effectiveness of functional mitochondria able to guarantee an adequate O 2 extraction at the skeletal muscles 5 . (
  • Exercise intolerance, the reduced ability to perform activities that involve dynamic movement of large skeletal muscles because of dyspnea or fatigue, may be one of the first symptoms experienced by patients with heart failure. (
  • The impairment in endothelial-dependent vasodilation correlates with the degree of exercise intolerance and severity of New York Heart Association class. (
  • Anaerobic metabolism that occurs early during exercise in patients with heart failure is likely an important cause of exercise intolerance. (
  • Exercise intolerance is a condition of inability or decreased ability to perform physical exercise at the normally expected level or duration for people of that age, size, sex, and muscle mass. (
  • Exercise intolerance is not a disease or syndrome in and of itself, but can result from various disorders. (
  • Dysfunctions involving the pulmonary, cardiovascular or neuromuscular systems have been frequently found to be associated with exercise intolerance, with behavioural causes also playing a part. (
  • For example, a person with exercise intolerance after a heart attack may not be able to sustain the amount of physical activity needed to walk through a grocery store or to cook a meal. (
  • Chronic pain that makes a person unwilling to undertake a physical activity is not, by itself, a form of exercise intolerance. (
  • Objective tests for exercise intolerance normally involve performing some exercise. (
  • In the six-minute walk test, the goal is to see how far the person can walk, with approximately 600 meters being a reasonable outcome for an average person without exercise intolerance. (
  • The CPET test measures exercise capacity and help determine whether the cause of exercise intolerance is due to heart disease or to other causes. (
  • People who experience significant fatigue before reaching the anaerobic threshold usually have a non-cardiac cause for exercise intolerance. (
  • Multiple sclerosis Cystic fibrosis: CF can cause skeletal muscle atrophy, however more commonly it can cause exercise intolerance. (
  • The exercise intolerance is associated with reduced pulmonary function that is the origin of CF. Bronchiectasis Post-exertional malaise is one of the main symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (
  • OI includes exercise intolerance as one of the main symptoms. (
  • Exercise intolerance is present in those with PCS however their intolerance to exercise may reduce over time. (
  • Individuals with postconcussion syndrome may also experience a level of exercise intolerance, however there is little known comparatively about exercise intolerance in PCS patients. (
  • Angina pectoris Heart failure: Exercise intolerance is a primary symptom of chronic diastolic heart failure. (
  • dyspnea and fatigue, these systems consequently contribute to exercise intolerance. (
  • In the heart the right ventricular (RV) can have a volume overload which ultimately produces a pressure overload in the RV resulting in exercise intolerance as the RV is no longer able to control high pressure associated with exercise. (
  • Chronic heart failure Spinal muscular atrophy: symptoms include exercise intolerance, cognitive impairment and fatigue. (
  • Patients with chronic heart failure (CHF) and/or chronic obstructive pulmonary disease (COPD) often have reduced exercise tolerance, limiting participation in daily activities. (
  • Exercise tolerance testing is an integral part of the pulmonary rehabilitation (PR) management of patients with chronic obstructive pulmonary disease (COPD). (
  • The aim of this study was to compare the results of the 6MST to those obtained during a 6-minute walk test (6MWT) and cardiopulmonary exercise testing (CPET) in a cohort of COPD patients. (
  • The results of this study show that the 6MST is a valid test to evaluate exercise tolerance in COPD patients. (
  • The measurement of operating lung volumes ( i.e. end-expiratory (EELV) and end-inspiratory lung volumes) during exercise is relevant to the understanding of the impairment-disability interface in chronic obstructive pulmonary disease (COPD) 8 . (
  • These factors together would improve exercise performance in COPD. (
  • Exercise limitation, dynamic hyperinflation, and exertional dyspnea are key features of symptomatic chronic obstructive pulmonary disease (COPD). (
  • We assessed the effects of glycopyrronium bromide (NVA237), a once-daily, long-acting muscarinic antagonist, on exercise tolerance in patients with moderate to severe COPD. (
  • BACKGROUND: Although pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest, the evidence of its effects on dynamic hyperinflation (DH) and exercise tolerance is scarce. (
  • AIM:To evaluate the effect of PLB on exercise tolerance, breathing pattern, dynamic hyperinflation and arterial oxygenation in COPD patients during high-intensity exercise. (
  • CLINICAL REHABILITATION IMPACT: This study points to a possible application of PLB in a selected group of COPD patients aiming at improving the exercise tolerance. (
  • Ventilatory capacity was significantly correlated with but a poor predictor of exercise tolerance. (
  • The distance walked in a 12-minute exercise test was significantly correlated with measurements of mood and with several attitudes and beliefs. (
  • Both systolic and diastolic blood pressure were significantly related to both alcohol intake and exercise tolerance levels in both men and women. (
  • Alcohol intake was not significantly correlated with exercise tolerance. (
  • Exercise tolerance values were significantly reduced compared to controls. (
  • Purpose: The purpose of this study was to quantify the impact of physical activity associated behaviors and exercise types significantly associated with high stress tolerance (HST) among college students. (
  • SPECT/CT imaging provides regional quantification of skeletal muscle perfusion reserve which is significantly associated with exercise tolerance and cardiovascular fitness. (
  • The magnitude and frequency of peak exercise ST-segment depression reduced significantly in the CSWT+OMT group compared with the OMT+placebo group at the 6-month follow-up (51.4 vs. 90.6%, P =0.001). (
  • The authors of a research study report published in the October 2007 issue of 'European Journal of Cardiovascular Prevention and Rehabilitation' reported that exercise tolerance is impaired and and the duration of time young, health men who smoke are able to tolerate exercise is significantly shorter compared to nonsmokers. (
  • 75 years) and women, independently, were significantly less likely to undergo exercise tolerance testing (exercise ECG) and cardiac catheterisation. (
  • Exercise tolerance is significantly compromised. (
  • The results from this study would provide preliminary data, using non-invasive methods, on oxidative capacity in ambulatory SMA patients and disease controls to aid in the design of exercise intervention studies. (
  • The difference between critical and recovery power ( D CP ), time constant for reconstitution of W´ ( \(\tau_{{W^{\prime}}}\) ), time to limit of tolerance ( T LIM ), and W´ BAL from the integral ( W´ BALint ), differential ( W´ BALdiff ), and locomotor-specific (OG- W´ BAL ) methods were compared. (
  • Methods: Research design employed was an quantitative, analytical, cross-sectional study of randomly selected college students (N = 936) that completed a stress tolerance questionnaire (STQ) coupled with a physical activity log. (
  • METHODS: In a randomized order, all patients performed PLB and control breathing (CB) during constant work-rate exercise in an electrically-braked cycloergometer. (
  • METHODS: Participants with and without LBP completed testing pre- and post-6 weeks of progressive home exercise intervention. (
  • METHODS: We examined the relation of two indices of physical activity-walking pace and leisure activity-to total mortality, CHD, and other cardiovascular diseases in a 25-year follow-up of 6408 male British Civil Servants who underwent an oral glucose tolerance test at study entry. (
  • This study aimed to evaluate muscle oxidative function during exercise in amyotrophic lateral sclerosis patients (pALS) with non-invasive methods in order to assess if determinants of reduced exercise tolerance might match ALS clinical heterogeneity. (
  • This approach appears to be more responsive than other tests, as it allows for placebo-controlled comparisons of symptoms and physiological parameters, including exercise endurance time (ET), at a standardised work rate or power output 5 , 7 . (
  • Unaddressed, these symptoms often result in depression and social isolation, causing further decline in exercise tolerance and functional performance. (
  • Thus, it is likely that diastolic dysfunction may limit exercise tolerance before resulting in symptoms at rest. (
  • The current study aimed to evaluate whether CSWT can improve exercise tolerance and relieve angina symptoms in addition to optimal medical treatment in patients with stable angina. (
  • 1 Proposed mechanisms for this positive effect on chemotherapy treatment tolerance include exercise-related amelioration of specific symptoms or toxicities that cause treatment reductions or delays, including neutropenia, fatigue, and neuropathy. (
  • Dyspnoea and decreased exercise tolerance are symptoms of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). (
  • The amount of exercise to be performed gradually increases over several minutesuntil the patient experiences excessive symptoms (e.g., fatigue, shortness of breath, chest pain, or claudication) or until objective findings of cardiopulmonary malfunction are demonstrated (e.g., arrhythmias, decreases in blood pressure, or ST-segment changes on the electrocardiogram). (
  • Exercise tests are used most often to help diagnose symptoms or signs suggestive of coronary ischemia. (
  • Fatigue and a decreased capacity to exercise are other symptoms that commonly result from heart failure. (
  • Iron metabolism is disturbed, and administration of iron might improve both symptoms and exercise tolerance. (
  • Conclusions: Intravenous iron loading improved exercise capacity and symptoms in patients with CHF and evidence of abnormal iron metabolism. (
  • Exercise endurance, inspiratory capacity (IC) during exercise, IC and expiratory volumes from spirometry, plethysmographic lung volumes, leg discomfort and dyspnea under exercise (Borg scales), and transition dyspnea index were measured on Days 1 and 21 of treatment. (
  • Exercise tolerance and dyspnea in patients with chronic obstructive pulmonary disease]. (
  • Frequently seen clinical features includes dyspnea, respiratory distress, recurrent pulmonary infections, and limited exercise tolerance. (
  • Overall, 28% of the variance in exercise tolerance was explained at baseline, 19% at 14 weeks, and 20% at 9 months. (
  • All idiopathic subjects with a baseline and study endpoint measurement of both hemodynamic and exercise endpoints were included. (
  • Exercise echocardiograms (Modified Bruce Protocol) and the Minnesota Living With Heart Failure questionnaire were administered at baseline, and after each two-week treatment period, separated by a two-week washout period. (
  • The aim of this parallel-group randomised controlled trial was to evaluate the effects of exercise training on pancreatic fat and beta cell function in healthy and prediabetic or type 2 diabetic participants and to test whether the responses were similar regardless of baseline glucose tolerance. (
  • Two weeks of exercise training improves beta cell function in prediabetic or type 2 diabetic individuals and decreases pancreatic fat regardless of baseline glucose tolerance. (
  • RESULTS: In 352 men who were identified as having Type 2 diabetes or impaired glucose tolerance (diabetes/IGT) at baseline, 215 had died at follow-up and, in 6056 normoglycaemics, 2550 deaths had occurred. (
  • Dyspnoea at baseline and after exercise and oxygen saturation (SpO 2 ) during exercise was measured. (
  • There were no statistical significant differences between the groups for the primary endpoint, change in the bicycle exercise tolerance test , from baseline to 6 months follow-up. (
  • In 50 patients with chronic bronchitis the relation was assessed between exercise tolerance and pulmonary function and psychological factors, including subjective perception of exertion, mood, general psychiatric disturbance, and the attitudes and beliefs held by patients concerning themselves, their illness, and its treatment. (
  • While early-stage CKD patients may show changes in pulmonary function and lowered exercise tolerance, the role of the estimated glomerular filtration rate (eGFR) in these patterns remains unknown. (
  • The aim of this study was to investigated pulmonary function and exercise tolerance in pre-dialytic CKD patients. (
  • Despite their potential relevance in CKD, exercise tolerance and pulmonary function have been little studied in pre-dialytic CKD patients [ 15 ] The aim of this study, therefore, was to evaluate the respiratory function and the exercise tolerance of pre-dialytic CKD patients in stages 3, 4, and 5. (
  • In contrast to the negative effects of many adipokines, our study identified transforming growth factor beta 2 (TGF-beta 2) as an adipokine released from adipose tissue (fat) in response to exercise that actually improves glucose tolerance," says Laurie J. Goodyear, PhD, Head of Joslin's Section on Integrative Physiology and Metabolism and study co-author. (
  • In response to exercise, an adipokine TGF beta 2 is released from the adipose tissue cells that improve glucose tolerance. (
  • Not only did exercise-stimulated TGF-beta 2 improve glucose tolerance, treating obese mice with TGF beta 2 lowered blood lipid levels and improved many other aspects of metabolism. (
  • The experiment showed a number of positive metabolic effects in the mice, including improved glucose tolerance and increased fatty acid uptake. (
  • Carbohydrate (CHO) also enhances exercise capacity ( 4 ) by maintaining blood glucose and enhancing CHO oxidation ( 3 ). (
  • Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control. (
  • Blood glucose concentrations will be sampled every 15 min following an oral glucose tolerance test. (
  • OBJECTIVE Individuals with impaired glucose tolerance (IGT) have a high risk of developing NIDDM. (
  • Impaired glucose tolerance (IGT) is a transitory state between normoglycemia and frank diabetes. (
  • More intense exercise prescriptions would appear to be needed to improve glucose tolerance and insulin action. (
  • Although higher exercise intensity is a key determinant for improvements in glucose homeostasis, it may produce mechanical and oxidative damage that can result in transitory impairments in insulin action and glucose tolerance. (
  • This transitory condition is known as impaired glucose tolerance (IGT). (
  • Exercise is often prescribed as an initial therapy to control elevations in blood glucose. (
  • However, guidelines that specifically address the use of exercise in controlling blood glucose in individuals with IGT have not been developed. (
  • mean ± SE) with impaired glucose tolerance (IGT) who were randomized to the American Heart Association (AHA) Step 2 diet plus endurance exercise ( n = 30) versus the AHA Step 1 diet plus stretching ( n = 32) for 24 months. (
  • The incremental area under the curve for glucose (incAUCg) was calculated from a 75-g oral glucose tolerance test. (
  • The benefit of lifestyle modifications for reducing the progression to type 2 diabetes in subjects with impaired glucose tolerance (IGT) has been demonstrated in several large randomized studies ( 2 - 4 ). (
  • Prediabetes (impaired fasting glucose and/or impaired glucose tolerance) and type 2 diabetes were defined by ADA criteria. (
  • AIMS: Given that studies of individuals with Type 2 diabetes or impaired glucose tolerance indicate that physical activity has a normalizing effect on several indices of coronary heart disease (CHD) risk-including body weight, blood pressure, blood lipids, and cardiorespiratory fitness-it is plausible that activity may reduce CHD incidence in this group in the long term. (
  • An exercise tolerance test (ETT) - also known as an exercise electrocardiogram (ECG) - can help to assess the severity of coronary heart disease. (
  • Exercise tolerance testing (ETT) is one method which is used to determine the presence of significant coronary heart disease. (
  • Equity in access to exercise tolerance testing, coronary angiography, and coronary artery bypass grafting by age, sex and clinical indications. (
  • OBJECTIVES: To assess whether patients with heart disease in a single UK hospital have equitable access to exercise testing, coronary angiography, and coronary artery bypass graft surgery (CABG). (
  • The exercise tolerance test evaluates the ability of your heart and lungs to provide oxygen and remove carbon dioxide from the bloodstream before, during and after you exercise. (
  • The exercise for desaturation test evaluates your oxygen needs at rest and during exercise. (
  • What is done during the Exercise Test? (
  • A technician will explain what you need to do during the exercise test. (
  • If you are doing the exercise tolerance test, you will be asked to ride a stationary bicycle. (
  • The Exercise Tolerance test often takes 2 hours. (
  • The Exercise for Desaturation test often takes 1½ hour. (
  • What is an Exercise Tolerance Test? (
  • An exercise tolerance test lets the physician see how well your heart functions when it works harder. (
  • When the exercise portion of the test is over, your EKG and blood pressure will continue to be monitored for several minutes. (
  • Participants will undergo an exercise stress test performed by a clinical exercise physiologist using an electronically-braked recumbent cycle ergometer to determine peak oxygen uptake (VO2 max). (
  • These recommendations were based on the demonstrations that the improvement in the maximum work rate attained on the ramp-type incremental exercise test, in response to a particular intervention, was relatively small and often close to the limit of the "minimum clinically important difference" 3 . (
  • In contrast, the change in time to the limit of tolerance ( t LIM ) on a constant-load test, chosen to be a high fraction of the maximum incremental work rate, was shown to be appreciably larger and hence considered to be more discriminatory, to the extent that investigators now often forego the post-intervention maximum incremental test 4 - 6 . (
  • 8 are, perhaps, even more striking: endurance training resulted in an average increase in the maximum incremental work rate of ∼20%, compared with ∼300% average increase in tolerance to a constant-load test. (
  • Mice that were able to exercise daily leading up to the cold test had a higher body temperature and lost less weight in their effort to stay warm. (
  • The aim of this study is to test our hypothesis that normal exercise tolerance differs according to gender and to identify potential functional cardiac relationships, which could explain those differences. (
  • An exercise tolerance test was completed upon entry into cardiac rehabilitation, after 14 weeks, and after 9 months. (
  • Exercise tolerance test demonstrating dynamic Brugada ECG pattern. (
  • The 6-minute stepper test (6MST) is a new, well-tolerated, reproducible exercise test, which can be performed without any spatial constraints. (
  • The aim of this study was to test the hypothesis that use of tiotropium, a new long-acting anticholinergic bronchodilator, would be associated with sustained reduction in lung hyperinflation and, thereby, would improve exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease. (
  • Participants completed a cycling-graded exercise test, heat acclimation state test, and a time to task failure (TTTF) at 80% peak power output in temperate (TTTFTEMP : 22°C/40% RH) and hot conditions (TTTFHOT : 38°C/20% RH), before and after 10-sessions (60 min of cycling at ~2 W·kg-1) in 45°C/20% RH (ODHA and TDHA) or 22°C/40% RH (ODTEMP or TDTEMP). (
  • Exercise tolerance by six-minute walk test, quadriceps muscle strength by a dynamometer and quality of life by Minnesota Questionnaire. (
  • Cardiopulmonary exercise testing, lung function tests, and echocardiographic study were performed on both the test and control groups to measure maximal aerobic capacity and cardiac function. (
  • The patients and controls (n=10) each for male and female groups were subjected to spirometry using computerised electronic spirometer while exercise tolerance was evaluated by modified Harvard step test. (
  • 2. Each subject performed two types of exercise test breathing three different gas mixtures: air, 35% oxygen in nitrogen and 21% oxygen in helium. (
  • The aim of the study was to test the hypothesis that angiotensin II (Ang II) blockade would improve exercise tolerance in patients with diastolic dysfunction and a marked increase in systolic blood pressure (SBP) during exercise. (
  • The purpose of this dissertation was to test the overarching hypothesis that muscle contraction characteristics (i.e., intensity of contraction, muscle contraction-relaxation duty cycle, etc.) alter oxygen delivery and oxygen utilization, which directly influence the power-duration relationship and fatigue development, and therefore, exercise tolerance. (
  • All participants underwent spirometric and manovacuometric tests, a cardiopulmonary exercise test (CPET), a 6-minute walk test (6MWT), and laboratory tests. (
  • Inspiratory capacity, dynamic hyperinflation, breathlessness, and exercise performance during the 6-minute-walk test in chronic obstructive pulmonary disease. (
  • Our study results showed that exercise tolerance test has high positive predictive value. (
  • Submaximal Clinical Exercise Tolerance Test - Case Example 1 (Jerry Mode: Schwinn AirDyne[TM] Cycle Ergometer Resting HR: 68 AAMHR: 162 * Resting BP: 136/76 85%AAMHR: 138 * Min Workload HR BP RPE 0-2 20 W 94 1 2-4 40 W 107 138/78 2 4-6 60 W 117 4 6-8 80 W 136 152/80 7 Test Interpretation: Moderate intensity arm/leg ergometry tolerated well. (
  • An exercise tolerance test is often used as part of a screening medical for certain jobs with safety critical responsibilities such as public service drivers, ie taxi, bus and train drivers, particularly after a heart attack or chest pain. (
  • Exercise tolerance was assessed by an incremental exercise test on cycle ergometer measuring peak O 2 uptake ( \(\dot{{\rm{V}}}\) O 2peak ), vastus lateralis oxidative function by near infrared spectroscopy (NIRS) and breathing pattern ( \(\dot{{\rm{V}}}\) E peak ). (
  • You should also avoid strenuous exercise for several hours before the test and refrain from smoking for 24 hours. (
  • If you feel you cannot continue, the test will be stopped, but it is important that you do as much exercise as possible for the results to be meaningful. (
  • Once the exercise section of the test has finished, you will be able to lie down, and your heart will be monitored with an ECG and a blood pressure machine until it returns to its resting rate. (
  • Dr Ruzicka will review and analyse your exercise test to see if the ECG tracings show any arrhythmias or signs of ischaemic heart disease. (
  • An exercise tolerance test (ETT) records the electrical activity of your heart whilst you exercise. (
  • Most people manage to do the exercise tolerance test (ETT). (
  • Are there any risks when doing an exercise tolerance test? (
  • An Exercise Tolerance Test as described above, but in addition, the patient breathes through a special mouthpiece to determine how much and how effectively the body uses oxygen. (
  • A normal exercise test may reassure many patients but it does not exclude a diagnosis of CAD. (
  • A cardiac stress test is a recording of the heart's activity during exercise. (
  • The exercise portion of the test generally takes less than 15 minutes. (
  • Background: Although many studies of heart failure therapies test improvements of patient condition in terms of mean changes of quality of life (QoL) or exercise tolerance (ET) measures, it is of increasing interest to quantify the proportion of patients that "respond" to therapy and understand factors predicting response. (
  • The three most common reasons people give for being unable to tolerate a normal amount of exercise or physical activity are: breathlessness - commonly seen in people with lung diseases, heart disease, and obesity fatigue - When it appears early in an exercise test, it is usually due to deconditioning (either through a sedentary lifestyle or while convalescing from a long illness), but it can indicate heart, lung, or neuromuscular diseases. (
  • Common tests include stair climbing, walking for six minutes, a shuttle-walk test, a cardiac stress test, and the cardiopulmonary exercise test (CPET). (
  • Spirometry, plethysmographic lung volumes, cycle exercise endurance and exertional dyspnoea intensity at 75% of each patient's maximal work capacity were compared. (
  • 2. The effects of 2 weeks on two levels of salt intake (50 and 150 mmol/day) on the ability to exercise (60% of maximal oxygen uptake) in a hot environment (35°C) were studied in eight healthy normotensive subjects. (
  • Women with Turner syndrome (TS) have lower maximal aerobic capacity and lower exercise tolerance than controls, according to a study published in the April 1 issue of The American Journal of Cardiology. (
  • The patients with TS had a lower maximal aerobic capacity and exercise tolerance than did the controls. (
  • Pre-dialytic CKD patients showed lower maximal and submaximal exercise tolerances than healthy individuals. (
  • In healthy persons, the increase in cardiac output during maximal upright exercise typically is four- to sixfold, which is accomplished by a two- to fourfold increase in heart rate and a 20 to 50 percent increase in stroke volume. (
  • Patients may have less than 50 percent of the maximal cardiac output of a healthy person at peak exercise. (
  • During control, patients were able to exercise for 11.3 ± 2.5 (mean ± SD) min, with a peak exercise SBP of 226 ± 24 mm Hg. (
  • With placebo, there was no improvement in exercise duration (11.0 ± 2.0 min) or peak exercise SBP (217 ± 26 mm Hg). (
  • Metabolic equivalents (METs) at peak exercise and heart rate recovery (HRR) after exercise were recorded. (
  • Dynamic hyperinflation, oxygen saturation and breathing pattern were recorded at rest, in isotime and in peak exercise. (
  • Results from Dr. Harris and colleague Dr. McKie's studies have indicated that during peak exercise the Cystic Fibrosis subjects consumed 14% less oxygen while their expelled air had higher oxygen levels, "indicating that their muscles were not as efficient at using it. (
  • Using a double-blind crossover design, ET and SED ( n = 12 each group) completed four exercise trials consisting of 30 min cycling at standardized matched work rates 10% below lactate threshold (MOD-EX) followed by a time to fatigue (TTF) ride at individually prescribed intensity of 5% above lactate threshold. (
  • Athletes ingest caffeine and carbohydrate to improve performance and delay fatigue during exercise ( 1 - 4 ). (
  • Whether a generalized fatigue prevents the undertaking of exercise or the acute discomfort/fatigue that directly results from exercise is the more relevant barrier remains unclear ( 6 ). (
  • The final investigation (Chapter 4) utilized periods of blood flow occlusion during and post-exercise to reveal greater magnitudes of peripheral and central fatigue development during blood flow occlusion exercise compared to control blood flow exercise. (
  • Rather, W' may be determined by the magnitude of fatigue accrued during exercise, which is dependent upon oxygen delivery and oxygen utilization. (
  • Fatigue of the respiratory muscles during intense exercise might compromise leg blood flow, thereby constraining oxygen uptake ( O2) and limiting exercise tolerance. (
  • This study tested the hypothesis that inspiratory muscle training (IMT) would reduce inspiratory muscle fatigue, speed O2 kinetics and enhance exercise tolerance. (
  • Caffeic acid is used in supplements for boosting athletic performance and has shown promise in reducing the fatigue associated with exercise, however research is limited. (
  • People who have fibromyalgia and chronic fatigue syndrome usually have a difficult time exercising because they often get exhausted quickly by even a moderate amount of exercise. (
  • Malic acid has been found to increase tolerance to exercise in people who have fibromyalgia and chronic fatigue syndrome, which allows them to exercise for longer time periods or at higher intensities. (
  • It also includes experiences of unusually severe post-exercise pain, fatigue, nausea, vomiting or other negative effects. (
  • or exercise might result in severe headache, nausea, dizziness, occasional muscle cramps or extreme fatigue, which would make it intolerable. (
  • No differences in mean oxygen uptake, heart rate or rectal temperature during exercise were observed between the two salt intakes. (
  • In the study 'Inspiratory muscle training enhances pulmonary O2 uptake kinetics and high-intensity exercise tolerance in humans' the results indicated that "the enhanced exercise tolerance observed after IMT might be related, at least in part, to improved Vo(2) dynamics, presumably as a consequence of increased blood flow to the exercising limbs. (
  • and (ii) whether the accelerated oxygen uptake kinetics following priming exercise can improve exercise tolerance. (
  • During the tests oxygen uptake, muscle oxygenation, muscle electrical activity and exercise tolerance were measured. (
  • A correlation was present between the change in tissue oxygenation index during bout 2 and the change in the phase II (r = -0.72, likely negative) and slow component (r = 0.72, likely positive) oxygen uptake amplitudes following priming exercise, but not for muscle activity. (
  • The altered phase II and slow component oxygen uptake amplitudes in boys following priming exercise are linked to an improved localised matching of muscle oxygen delivery to oxygen uptake and not muscle electrical activity. (
  • Despite more rapid oxygen uptake kinetics following priming exercise, exercise tolerance was not enhanced. (
  • The factors that limit exercise capacity may be different in patients with different disease entities (i.e., chronic obstructive, restrictive or pulmonary vascular lung disease) or disease severity and ultimately depend on the degree of malfunction or miss coordination between the different physiological systems (i.e., respiratory, cardiovascular and peripheral muscles). (
  • Exercise tolerance or physiological fitness appears to be important in quantifying the relation between alcohol intake and blood pressure and should be considered in describing this relation. (
  • In view of the abnormal physiological adaptations to exercise in patients with CF with advanced lung disease (PFS greater than 12), they should engage in exercise training programs and strenuous physical activity with caution and only after their cardiorespiratory reserves and adjustments to exercise have been objectively evaluated. (
  • Without knowledge of these features, any absolute or per cent increase in tolerance time to a single constant-load exercise bout must be interpreted with caution regarding the physiological benefit(s) that have accrued from the intervention. (
  • The physiological mechanisms determining the tolerable duration of exercise dictate human physical accomplishments across all spectrums of life. (
  • The novel findings of the investigations presented in this dissertation highlight important physiological mechanisms that determine exercise tolerance and demonstrate the need for interventions that improve oxygen delivery and oxygen utilization in specific populations, such as those with chronic heart failure or chronic obstructive pulmonary disease, to improve exercise tolerance. (
  • CONCLUSIONS Diet and/or exercise interventions led to a significant decrease in the incidence of diabetes over a 6-year period among those with IGT. (
  • CONCLUSIONS: PVRI should not be used as a surrogate marker to predict changes in exercise capacity. (
  • Conclusions: This study demonstrated the positive protective impact of physical activity behaviors and exercise on stress tolerance among college students. (
  • Conclusions Pharmacotherapy of heart failure with preserved ejection fraction demonstrates a quantifiable improvement in exercise tolerance but not mortality. (
  • CONCLUSIONS: Individuals with LBP meeting clinical prediction rules for stabilization-based exercise demonstrated increased standing tolerance and sagittal plane muscle sequencing following a 6-week intervention. (
  • The objective of this study was to investigate the effect of a fast skeletal troponin activator, CK-2127107 (2-aminoalkyl-5- N -heteroarylpyrimidine), on skeletal muscle function and exercise performance in rats exhibiting heart failure-mediated skeletal myopathy. (
  • Although exercise is often prescribed for the management of cardiovascular diseases, a non-invasive imaging approach that quantifies skeletal muscle physiology and correlates with patients' functional capacity and cardiovascular fitness has been absent. (
  • Future application of SPECT/CT may elucidate the underlying skeletal muscle adapations to exercise therapy in patients with cardiovascular diseases. (
  • Inefficient skeletal muscle O 2 function, when flanking the impaired motor units recruitment, is a major determinant of pALS clinical heterogeneity and working capacity exercise tolerance. (
  • In pALS this phenomenon has not been fully characterized in term of the underlying governing dynamics of oxidative metabolism, and specifically by assessing skeletal muscle oxidative function during exercise. (
  • Oral taurine improves critical power and severe-intensity exercise tolerance. (
  • Magnitude of spinal muscle damage is not statistically associated with exercise-induced low back pain intensity. (
  • CAF also has neuromodulatory effects in the brain enhancing task persistence and determination likely through adenosine inhibition ( 10 , 15 ), thus, allowing individuals to perform more work at the same effort or perceive the same exercise intensity as more tolerable and/or less painful ( 1 , 2 , 16 , 17 ). (
  • Recent physical activity guidelines from the Centers for Disease Control and Prevention and the American College of Sports Medicine have suggested that intermittent moderate-intensity exercise is beneficial and can improve the health status of these individuals. (
  • Therefore, the optimal exercise intensity for an individual with IGT appears to lie between these two extremes. (
  • 2 Specifically, they have suggested that every American should accumulate 30 min of moderate-intensity exercise on most, if not all, days of the week. (
  • Walking briskly (3-4 miles per hour), gardening, and general home-care activities have been classified as moderate-intensity exercise. (
  • The current activity guidelines are based primarily on epidemiological data that suggest that those who perform 30 min of moderate-intensity exercise per day have lower morbidity and mortality rates than those who are habitually inactive. (
  • Although a wealth of epidemiological data support the current guidelines, little clinical evidence exists that would suggest that intermittent moderate-intensity exercise by itself would be beneficial in improving glycemic status. (
  • Individuals differ in the intensity of exercise they prefer and the intensity they can tolerate. (
  • The purpose of this project was to develop a measure of individual differences in the preference for and tolerance of exercise intensity. (
  • The Preference for and Tolerance of the Intensity of Exercise Questionnaire (PRETIE-Q) is a 16-item, 2-factor measure that exhibits acceptable psychometric properties and can be used in research aimed at understanding individual differences in responses to exercise and thus the psychological processes involved in the public health problem of exercise dropout. (
  • Furthermore, improving the (nutritional) conditions under which exercise promotes muscle protein synthesis is not only important for athletes, but also in clinical conditions requiring enhanced anabolic response in patients who are unable to perform high-intensity exercise. (
  • Intensity of exercise is measured in metabolic equivalents (METs) where 1 MET is the amount of energy expended at rest or 3.5 ml oxygen per kilogram per minute. (
  • Seven boys that were aged 11.3 ± 1.6 years completed either a single bout (bout 1) or repeated bouts with 6 min of recovery (bout 2) of very heavy-intensity cycling exercise. (
  • Essential Amino Acids and Exercise Tolerance in Elderly Muscle-Depleted Subjects with Chronic Diseases: A Rehabilitation without Rehabilitation? (
  • The enduring impact of social factors on exercise tolerance in men attending cardiac rehabilitation. (
  • RESULTS: Sociodemographic factors and social support reported upon entry into the cardiac rehabilitation program were related to initial and post-cardiac rehabilitation exercise tolerance, after controlling for admitting diagnoses, medical history, smoking, and perceived severity of illness. (
  • The reduced exercise tolerance in pALS ( i . e ., the capacity to maintain workloads ranging from habitual activities to rehabilitation exercises) has been associated with mitochondrial dysfunction, both as a direct pathogenic mechanism and as a factor contributing to the exercise limitation 5 , 6 . (
  • Resultant increases in inspiratory capacity permitted greater expansion of tidal volume and contributed to improvements in both exertional dyspnoea and exercise endurance. (
  • Effect of inspiratory pressure support on exercise tolerance and breathlessness in patients with severe stable chronic obstructive pulmonary disease. (
  • 6MWT is an objective evaluation of functional exercise capacity, measures the maximum distance a person can walk in six minutes over a 25-meter linear course. (
  • The haemoglobin concentration did not correlate with 6MWT, dyspnoea during 6MWT, or exercise oxygenation and blood desaturation during exercise. (
  • Researchers assessed each patient's response through spirometry tests , and compared the changes to those seen in exercise capacity tests, including the 6MWT, and other lung function tests. (
  • She owns Moxie Personal Training and is pursuing a Bachelor of Science in exercise physiology at Portland State University. (
  • Aerobic exercise can benefit your health in many ways. (
  • This study compared chemotherapy treatment tolerance and survival among women receiving adjuvant chemotherapy for early-stage breast cancer who participated in a single-arm trial of supervised aerobic and resistance exercise programming versus a historical cohort that did not receive structured exercise programming. (
  • Furthermore, although C a O 2 was reduced by approximately 50% at the highest P CO 2 , there was no effect of hypercapnia on the eels' tolerance of hypoxia, aerobic metabolic scope or sustained swimming performance. (
  • The aim of this study was to evaluate the impact of aerobic and resistance exercise training modalities on arterial remodeling in patients with chronic heart failure. (
  • 3 , 6 , - , 9 However, few previous studies have directly compared the effects of resistance and aerobic exercise training in CHF patients. (
  • To evaluate exercise tolerance. (
  • OBJECTIVES: This study was designed to assess the prevalence of provoked exercise desaturation (PED) in patients with patent foramen ovale (PFO) referred for cardiovascular evaluation and to evaluate the impact of PFO closure. (
  • Therefore, this study was designed to evaluate the effects of tiotropium on exercise endurance and exertional dyspnoea, and to examine possible mechanisms for this overall functional improvement. (
  • The aim of this study is to evaluate the benefits on perceived quality of life (QOL) and physical fitness of a home-based physical exercise program compared to usual care, for patients with stabilised, generalised auto-immune MG. (
  • Exercise testing is used to evaluate the heart and lung function of children. (
  • The ability to increase the cardiac output during exercise without an abnormal elevation in left atrial pressure depends on the capacity of the left ventricle to enhance its diastolic filling (4) . (
  • Although cardiovascular disease limits the increase of cardiac output during exercise, this response also is affected by age, gender, and conditioning status. (
  • Regional blood flow in chronic heart failure: the reason for the lack of correlation between patients' exercise tolerance and cardiac output? (
  • Right heart dysfunction [] Numerous mechanisms unrelated to hemodynamic dysfunction may underlie impaired exercise tolerance in patients with chronic heart failure. (
  • Exercise training is an important adjunct to medical therapy in chronic heart failure, but the extent to which exercise impacts on conduit artery remodeling is unknown. (
  • Our findings suggest that exercise has a systemic impact on remodeling of conduit arteries in humans and that resistance exercise training may be advantageous in subjects with chronic heart failure in this regard. (
  • Exercise training in chronic heart failure (CHF) patients is associated with improved prognosis, 1 , 2 functional capacity, 2 , 3 and quality of life. (
  • Effect of Intravenous Iron Sucrose on Exercise Tolerance in Anemic and Nonanemic Patients With Symptomatic Chronic Heart Failure and Iron Deficiency. (
  • The effect of oral and intravenous tolamolol on exercise tolerance was assessed in 11 patients with angina pectoris. (
  • Effects of Molsidomine on global and regional left ventricular function at rest and during exercise in patients with angina pectoris. (
  • Haemodynamic and electrocardiographic effects of frusemide during supine exercise in patients with angina pectoris. (
  • Exercise testing is potentially hazardous to patients with unstable angina pectoris, myocardial infarction within the last 48 hours, uncontrolled heart failure, aortic dissection, pulmonary embolism, ataxia or severe arthritic disease. (
  • Most patients with suspected angina were traditionally referred for exercise ECG testing. (
  • [ 5 ] The 2010 National Institute for Health and Care Excellence (NICE) guidance for patients presenting with chest pain recommends that exercise ECG should not be used to diagnose or exclude stable angina for people without known CAD. (
  • In conclusion, the use of tiotropium was associated with sustained reductions of lung hyperinflation at rest and during exercise. (
  • According to the current authors' hypothesis, use of once-daily tiotropium would be associated with improved tidal expiratory flow rates (and lung emptying), reduced resting and exercise lung hyperinflation, and consequent alleviation of exertional dyspnoea. (
  • Exercise tolerance and cardiorespiratory adjustments at peak work capacity (PWC) were determined in 20 patients with cystic fibrosis (CF) during progressive cycle ergometry. (
  • We recently came across an article that reported on how patients with Cystic Fibrosis (CF) have less exercise capacity than their peers, even though their lungs may be relatively healthy. (
  • ILD and PVD are included because there is sufficient experimental evidence for the factors that limit exercise capacity and because these disorders are representative of restrictive and pulmonary vascular disorders, respectively. (
  • The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 patients with severe chronic bronchitis and emphysema (mean forced expiratory volume in one second 0.56 1, mean forced vital capacity 1.54 1). (
  • This proposal will focus on (1) estimating oxidative capacity of specific muscle groups during exercise using near infrared spectroscopy and (2) describing body composition to better understand exercise capacity and mitochondrial function in ambulatory spinal muscular atrophy (SMA) patients and disease controls. (
  • Thus, normal exercise capacity as determined by pVO(2) is related to the indexed stroke volume in males and left atrial pressure in females. (
  • BACKGROUND: Clinical trials for adults with pulmonary arterial hypertension use exercise capacity, as measured by walking distance, as the primary endpoint to measure symptomatic improvement. (
  • RESULTS: There is a weak correlation between changes in PVRI and exercise capacity. (
  • The exercise capacity, ventilation and heart rate were recorded. (
  • 3. (a) Effort tolerance at a constant load (70% capacity breathing air) was greater when the inspired gas mixture was 35% oxygen in nitrogen than when air or 21% oxygen in helium was breathed. (
  • Objectives We sought to determine whether pharmacologic interventions changed exercise capacity, diastolic function, and mortality in a meta-analysis of trials in heart failure with preserved ejection fraction. (
  • A correlation between resting ventricular function and exercise capacity is expected, but data indicate that the relationship is weak. (
  • In patients with heart failure, blood flow to muscles does not increase normally during exercise because of reduced cardiac output and impaired peripheral vasodilatory capacity. (
  • Exercise tolerance depends on the capacity of the pulmonary system to deliver oxygen to the working muscle and the capacity of the vasculature to redistribute cardiac output to the muscle during exercise. (
  • Knuth and Wright sought to distinguish the relative contribution of shivering (muscle) and non-shivering (fat) mechanisms in keeping mice warm - and whether exercise could improve the mouse's tolerance. (
  • However, to the researchers' surprise, "non-shivering" mechanisms could not explain the cold-protection conferred by exercise in these mice. (
  • Improvements in exercise endurance increased over time, suggesting that mechanisms beyond improved lung function may be involved in enhanced exercise tolerance. (
  • The purpose of this study was to determine whether diet and exercise interventions in those with IGT may delay the development of NIDDM, i.e., reduce the incidence of NIDDM, and thereby reduce the overall incidence of diabetic complications, such as cardiovascular, renal, and retinal disease, and the excess mortality attributable to these complications. (
  • A consequence of most cardiovascular diseases is exercise limitation. (
  • la actividad física a menudo se prescribe como parte del tratamiento de enfermedades cardiovasculares, sin embargo, en la actualidad no existe un enfoque de evaluación no invasiva que cuantifique la fisiología del músculo esquelético y se correlacione con la capacidad funcional y el estado cardiovascular de los pacientes. (
  • When used in the evaluation of patients with cardiovascular disease, exercise testing is often combined with echocardiography or nuclear imaging of the heart to improve the predictive value, sensitivity, and specificity of the assessment. (
  • If arterial blood gas samples will be taken while you exercise a catheter will be placed in an artery in your arm. (
  • The results indicate that whenever pulmonary disease in CF is advanced, there are decreases in exercise tolerance and cardiorespiratory reserves, exercise-induced ventilation-perfusion abnormalities, arterial desaturation, and alveolar hypoventilation. (
  • Is pulmonary vascular resistance index predictive of exercise tolerance in adult patients with idiopathic pulmonary arterial hypertension. (
  • Systolic arterial pressure normally increases during exercise. (
  • In elderly and hypertensive subjects the increase in systolic arterial pressure during exercise is frequently exaggerated (6-8) . (
  • Wall thickness and wall:lumen ratio have been used in peripheral conduit arteries to reflect arterial remodeling, 11 , - , 13 a process that may depend on exercise-mediated changes in systemic hemodynamics and arterial shear stress. (
  • 14 , - , 18 We recently reported important differences in the impact of different exercise modalities on systemic changes in shear stress during bouts of exercise, 19 a finding which raises the possibility that distinct forms of exercise may induce differential changes in arterial size and wall thickness in humans. (
  • The curvilinear relationship between athletic performance and time was originally described by Hill ( 1925 ), where constant power output maintained to the limit of tolerance ( T LIM ) declined as a function of exercise duration. (
  • What is Exercise for Desaturation testing? (
  • Provoked exercise desaturation in patent foramen ovale and impact of percutaneous closure. (
  • Our purpose was to determine if these ergogenic aids are also effective to improve exercise tolerance in age-matched sedentary (SED) adults. (
  • Recently, the American College of Sports Medicine (ACSM), the Centers for Disease Control and Prevention (CDC), and the Surgeon General (SG) have issued statements regarding the recommended quantity and quality of exercise required to improve health status. (
  • 4. It is concluded that a reduction in the density of the inspired gas does not improve effort tolerance in patients with COB. (
  • Available preliminary evidence is conflicting on whether exercise can positively influence antineoplastic treatment tolerance and in turn improve survival. (
  • KE has recently been shown to improve exercise performance, but whether it can also promote post-exercise muscle protein or glycogen synthesis is unknown. (
  • A single bout of exercise can acutely improve insulin sensitivity, but this effect dissipates over several days ( 12 - 15 ). (
  • Longer-term exercise interventions revealed little effect to improve insulin sensitivity if changes in weight were prevented ( 16 ) or if changes in weight attained during increased physical activity are matched to those attained by restriction of calorie intake ( 17 ). (
  • Dynamic IC at exercise isotime and trough FEV 1 showed significant and clinically relevant improvements from Day 1 of treatment that were maintained throughout the study. (
  • Once- and twice-daily heat acclimation conferred similar magnitudes of heat adaptation and exercise tolerance improvements, without differentially altering immune function, thus nonconsecutive TDHA provides an effective, logistically flexible method of HA, benefitting individuals preparing for exercise-heat stress. (
  • Results showed that treatment with Orkambi led to significant improvements in patient's exercise tolerance as seen at 4 weeks. (
  • Subjective perception of exertion was most closely correlated with exercise tolerance. (
  • Exercise tolerance testing is commonly used to determine the cause of chest pain and dyspnoea on exertion. (
  • Two years ago, the international research team first demonstrated that adipose tissue offers beneficial metabolic effects in response to exercise. (
  • This reversed the negative metabolic effects of the high fat diet, similar to what happens with exercise. (
  • Our results are important because it's really the first demonstration of an exercise-released adipokine that can have beneficial metabolic effects on the body," says Goodyear. (
  • This research really revolutionizes the way we think about exercise, and the many metabolic effects of exercise. (
  • SED and ET only differed in metabolic oxidation rates during exercise (higher overall fat oxidation with ET compared to SED). (
  • Ergoreceptors, which mediate circulatory adaptations in the early stages of exercise, are stimulated by metabolic acidosis and are partially responsible for sympathetic vasoconstriction and an increase in heart rate. (
  • They also are frequently used after patients have suffered a myocardial infarction or an exercise-induced arrhythmia. (
  • The NICE guidance also states that, for people with confirmed CAD (eg, previous myocardial infarction, revascularisation, previous angiography), non-invasive functional testing should be offered when there is uncertainty about whether chest pain is caused by myocardial ischaemia, and that exercise ECG may be used instead of functional imaging. (
  • Aerobics is a physical exercise that includes activities like dance, cycling, running, stretching and many more. (
  • Statistical differences by type of physical activity and stress tolerance were determined by Chi-Square and Odds Ratio (95%CI). (
  • Research exploring the effects of physical exercise in auto-immune myasthenia gravis (MG) is scarce. (
  • It is hypothesised that exercise could have positive physical, psychological as well as immunomodulatory effects and may be a beneficial addition to current pharmacological management of this chronic disease. (
  • The experimental group will undertake a 40-min home-based physical exercise program using a rowing machine, three times a week for three months, as an add-on to usual care. (
  • This is the largest randomised controlled trial to date evaluating the benefits and tolerance of physical exercise in this patient population. (
  • Anecdotal evidence from patients with MG suggests that those who participate in regular physical exercise feel better. (
  • Exercise in this context means physical activity, not specifically exercise in a fitness program. (
  • During the increased ventilation of exercise in flow-limited patients, EELV acutely increases above an already high resting value. (
  • FES improves MSNA and vasoconstriction and increases exercise tolerance, muscle strength and quality of life in hospitalised HF patients. (
  • In patients with Doppler evidence of diastolic dysfunction at rest and a hypertensive response to exercise, Ang II receptor blockade blunts the hypertensive response to exercise, increases exercise tolerance and improves quality of life. (
  • Specifically, older individuals had poorer exercise tolerance, whereas those with more income had better exercise tolerance. (
  • BACKGROUND: Healthy individuals who develop low back pain (LBP) during standing (standing intolerant) respond favorably to stabilization-based exercise interventions. (
  • People with clinical LBP meeting clinical prediction rules for stabilization-based exercise share characteristics with standing into lerant individuals. (
  • OBJECTIVE: To investigate the impact of stabilization-based exercise on standing tolerance, muscle activation and clinical measures in individuals with LBP meeting clinical prediction rules for stabilization-based exercise. (
  • The relations of systolic and diastolic blood pressures to alcohol intake and exercise tolerance levels in 15,612 men and 3,855 women were investigated. (
  • Diastolic dysfunction may be exacerbated during exercise, especially if there is a marked increase in SBP. (
  • Angiotensin II may contribute to the hypertensive response to exercise and impair diastolic performance. (
  • However, the extremely large variability of the improvement in this particular index of tolerance undermines the ability to make general inferences for the underlying functional improvement. (
  • The improvement in health status is likely to be multifactorial, but enhanced symptom control and increased exercise capability are potentially important factors. (
  • NVA237 50 µg once daily produced immediate and significant improvement in exercise tolerance from Day 1. (
  • 2 , 5 In addition, exploratory long-term follow-up of 2 large RCTs showed that exercise was associated with a (non-statistically significant) 32% to 34% improvement in DFS. (
  • In conclusion, exercise combined with weight loss enhances postabsorptive fat oxidation, which appears to be a key aspect of the improvement in insulin sensitivity in obesity. (
  • Improvement in exercise tolerance is an important outcome to consider in those with more severe airways disease," the researchers said. (
  • Exercise to get healthy - that way, you'll last longer at it and get better results. (
  • 6. On the basis of these results it is concluded that moderate salt restriction does not impair the ability to exercise in a hot environment. (
  • Results The mean exercise time improved in both study arms - CSWT and placebo treatment - at the 3- and 6-month follow-up, without a significant difference between groups. (
  • Our results indicate that adding KE to a standard post-exercise recovery beverage enhances the post-exercise activation of mTORC1 but does not affect muscle glycogen resynthesis in young healthy volunteers. (