An antidepressive agent that has also been used in the treatment of movement disorders. The mechanism of action is not well understood.
AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.
Compounds possessing both a hydroxyl (-OH) and an amino group (-NH2).
A viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.
An enzyme that catalyzes the deamination of ethanolamine to acetaldehyde. EC 4.3.1.7.
The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Proteins which are synthesized as a single polymer and then cleaved into several distinct proteins.
A genus of bacteria which may be found in the feces of animals and man, on vegetation, and in silage. Its species are parasitic on cold-blooded and warm-blooded animals, including man.
Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.
In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION.
Created 7 April 1992 as a result of the division of Yugoslavia.
A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE.
A group of fatty acids that contain 18 carbon atoms and a double bond at the omega 9 carbon.
Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
Prudent standard preventive measures to be taken by professional and other health personnel in contact with persons afflicted with a communicable disease, to avoid contracting the disease by contagion or infection. Precautions are especially applicable in the diagnosis and care of AIDS patients.
Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.
Mechanical food dispensing machines.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
The profession of writing. Also the identity of the writer as the creator of a literary production.
A publication issued at stated, more or less regular, intervals.
The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Books containing photographs, prints, drawings, portraits, plates, diagrams, facsimiles, maps, tables, or other representations or systematic arrangement of data designed to elucidate or decorate its contents. (From The ALA Glossary of Library and Information Science, 1983, p114)
Bovine respiratory disease found in animals that have been shipped or exposed to CATTLE recently transported. The major agent responsible for the disease is MANNHEIMIA HAEMOLYTICA and less commonly, PASTEURELLA MULTOCIDA or HAEMOPHILUS SOMNUS. All three agents are normal inhabitants of the bovine nasal pharyngeal mucosa but not the LUNG. They are considered opportunistic pathogens following STRESS, PHYSIOLOGICAL and/or a viral infection. The resulting bacterial fibrinous BRONCHOPNEUMONIA is often fatal.
Procedures outlined for the care of casualties and the maintenance of services in disasters.
Large vessels propelled by power or sail used for transportation on rivers, seas, oceans, or other navigable waters. Boats are smaller vessels propelled by oars, paddles, sail, or power; they may or may not have a deck.
The portion of an interactive computer program that issues messages to and receives commands from a user.
A genus of gram-negative, chemolithoautotrophic bacteria in the family Halothiobacillaceae. Several of its species were reclassified to this genus from THIOBACILLUS.
Sequential operating programs and data which instruct the functioning of a digital computer.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.

Carcinogenicity of triethanolamine in mice and its mutagenicity after reaction with sodium nitrite in bacteria. (1/1992)

Mice fed a diet containing 0.3 or 0.03% triethanolamine developed malignant tumors. Females showed a high incidence of tumors in lymphoid tissues, while this type was absent in males. Tumors in other tissues were produced at a considerable rate in both sexes, but no hepatoma was found. Triethanolamine was not mutagenic to Bacillus subtilis by itself, but it became mutagenic after reacting with sodium nitrite under acidic conditions or when the mixture was heated. Although N-nitrosodiethanolamine, a known carcinogen and mutagen, was detected in the reaction mixture by thin-layer chromatography, it may not be the main mutagenic product, because the product was a stable and direct mutagen and its mutagenic activity was destroyed by liver enzymes, unlike N-nitrosodiethanolamine. The lethal and mutagenic DNA damages produced by this unidentified product were susceptible to some extent to the repair functions of the bacteria.  (+info)

Dietary control of triglyceride and phospholipid synthesis in rat liver slices. (2/1992)

1. The effect of dietary manipulation on the synthesis of triglycerides and phospholipids was investigated by determining the incorporation of labeled long-chain fatty acid or glycerol into these lipids in liver slices derived from normally fed, fasted, and fat-free refed rats. 2. Triglyceride synthesis was affected markedly by the dietary regime of the animal; the lowest rates were measured with fasted rats, and the highest ones with fat-free refed rats. 3. In contrast to triglyceride synthesis, phospholipid synthesis occured at virtually constant rates regardless of the dietary conditions. 4. Addition of large amounts of fatty acid to the incubation mixture resulted in a marked stimulation of triglyceride synthesis, whereas phospholipid synthesis was affected to a much smaller extent. 5. These results indicate that the synthesis of triglycerides and that of phospholipids are controlled independently, and that the availability of fatty acid in the cell contributes to the control of triglyceride synthesis.  (+info)

Kinetic analysis of drug-receptor interactions of long-acting beta2 sympathomimetics in isolated receptor membranes: evidence against prolonged effects of salmeterol and formoterol on receptor-coupled adenylyl cyclase. (3/1992)

The long-acting beta2 sympathomimetics salmeterol and formoterol have been presumed to exert their prolonged action either by binding to an accessory binding site ("exo-site") near the beta2 adrenoceptor or by their high affinity for beta2 adrenoceptors and correspondingly slow dissociation. Whereas most studies with salmeterol had been done in intact tissues, which have slow diffusion and compartmentation of drugs in lipophilic phases, that restrict drug access to the receptor biophase, we used purified receptor membranes from rat lung and disaggregated calf tracheal myocytes as model systems. Binding experiments were designed to measure the slow dissociation of agonists by means of delayed association of (-)-[125I]iodopindolol. Rat lung membranes were pretreated with high concentrations of agonists (salmeterol, formoterol, isoprenaline) before dissociation was induced by 50-fold dilution. Half-times of association of (-)-[125I]iodopindolol remained unchanged compared with untreated controls, indicating that dissociation of agonists occurred in less than 2 min. Adenylyl cyclase experiments were designed to determine the on and off kinetics of agonists to beta2 adrenoceptors by measuring the rate of receptor-induced cyclic AMP (cAMP) formation. Experiments were performed in tracheal membranes characterized by high Vmax values of cAMP formation. Adenylyl cyclase activation occurred simultaneously with the addition of the agonist, continued linearly with time for 60 min, and ceased immediately after the antagonist was added. Similarly, when receptor membranes were preincubated in a small volume with high salmeterol concentrations, there was a linear increase in cAMP formation, which was immediately interrupted by a 100-fold dilution of the reaction mixture. This militates against the exo-site hypothesis. On the other hand, dissociation by dilution was much less when membranes were preincubated with a large volume of salmeterol at the same concentration, indicating that physicochemical effects, and not exo-site binding, underlie its prolonged mode of action.  (+info)

Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy. (4/1992)

The aim of the present study was to investigate bronchoprotective sensitivity in patients receiving regular treatment with short- and long-acting beta2-agonists and to evaluate any possible association with genetic polymorphism. Thirty-eight patients with stable mild to moderate asthma and receiving inhaled corticosteroids were randomized in a parallel group, double-blind, double-dummy fashion to receive 2 weeks of treatment with either formoterol (12 microg once daily, 6 microg twice daily or 24 microg twice daily) or terbutaline (500 microg four times daily). Bronchoprotection against methacholine challenge (as a provocative dose to produce a 20% fall in forced expiratory volume in 1.0 s: PD20) was measured at baseline (unprotected) after an initial 1 week run-in without beta2-agonist, and at 1 h after the first and last doses of each treatment. The PD20 values were log-transformed and calculated as change from baseline. Percentage desensitization of log PD20 for first- versus last-dose bronchoprotection was calculated and analysed according to effects of treatment and beta2-adrenoceptor polymorphism at codon 16 or 27. The mean degree of desensitization for bronchoprotection was comparable with all four treatments and there were no significant differences in absolute PD20 values after 2 weeks of chronic dosing. The PD20 values were (as microg of methacholine, geometric means+/-S. E.M.): formoterol, 12 microg once daily, 99+/-42 microg; formoterol, 6 microg twice daily, 107+/-44 microg; formoterol, 24 microg twice daily, 108+/-45 microg; terbutaline, 500 microg four times daily, 88+/-37 microg. All patients receiving formoterol, 24 microg twice daily, exhibited a loss of protection greater than 30% which was unrelated to polymorphism at codon 16 or 27. For codon 16, the use of lower doses of formoterol (12 microg once daily or 6 microg twice daily) showed wider variability in the propensity for protection loss in patients who were heterozygous, in contrast to a more uniform protection loss seen with homozygous glycine patients. The amount of protection loss was not significantly related to polymorphism at codon 16 or 27, expressed as values (mean+/-S.E.M.) for percentage desensitization according to each genotype (pooled treatments): Gly-16, 66+/-11%; Het-16, 53+/-8%; Arg-16, 69+/-18%; Glu-27, 68+/-12%; Het-27, 58+/-8%; Gln-27, 52+/-12%. The results of this preliminary study showed that bronchoprotective desensitization occurred readily in response to short- or long-acting beta2-agonist exposure irrespective of beta2-adrenoceptor polymorphism at codon 16 or 27. Further studies with larger patient numbers are required to further evaluate the effects of polymorphisms with lower doses of regular formoterol.  (+info)

Effects of tumour necrosis factor-alpha on left ventricular function in the rat isolated perfused heart: possible mechanisms for a decline in cardiac function. (5/1992)

1. The cardiac depressant actions of TNF were investigated in the isolated perfused rat heart under constant flow (10 ml min(-1)) and constant pressure (70 mmHg) conditions, using a recirculating (50 ml) mode of perfusion. 2. Under constant flow conditions TNF (20 ng ml(-1)) caused an early (< 25 min) decrease in left ventricular developed pressure (LVDP), which was maintained for 90 min (LVDP after 90 min: control vs TNF; 110 +/- 4 vs 82 +/- 10 mmHg, P < 0.01). 3. The depression in cardiac function seen with TNF under constant flow conditions, was blocked by the ceramidase inhibitor N-oleoylethanolamine (NOE), 1 microM, (LVDP after 90 min: TNF vs TNF with NOE; 82 +/- 10 vs 11 +/- 5 mmHg, P < 0.05). 4. In hearts perfused at constant pressure, TNF caused a decrease in coronary flow rate (change in flow 20 min after TNF: control vs TNF; -3.0 +/- 0.9 vs -8.7 +/- 1.2 ml min(-1), P < 0.01). This was paralleled by a negative inotropic effect (change in LVDP 20 min after TNF: control vs TNF; -17 +/- 7 vs -46 +/- 6 mmHg, P < 0.01). The decline in function was more rapid and more severe than that seen under conditions of constant flow. 5. These data indicate that cardiac function can be disrupted by TNF on two levels, firstly via a direct, ceramidase dependant negative inotropic effect, and secondly via an indirect coronary vasoconstriction.  (+info)

MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast. (6/1992)

Glycosylphosphatidylinositol (GPI)-anchored proteins are cell surface-localized proteins that serve many important cellular functions. The pathway mediating synthesis and attachment of the GPI anchor to these proteins in eukaryotic cells is complex, highly conserved, and plays a critical role in the proper targeting, transport, and function of all GPI-anchored protein family members. In this article, we demonstrate that MCD4, an essential gene that was initially identified in a genetic screen to isolate Saccharomyces cerevisiae mutants defective for bud emergence, encodes a previously unidentified component of the GPI anchor synthesis pathway. Mcd4p is a multimembrane-spanning protein that localizes to the endoplasmic reticulum (ER) and contains a large NH2-terminal ER lumenal domain. We have also cloned the human MCD4 gene and found that Mcd4p is both highly conserved throughout eukaryotes and has two yeast homologues. Mcd4p's lumenal domain contains three conserved motifs found in mammalian phosphodiesterases and nucleotide pyrophosphases; notably, the temperature-conditional MCD4 allele used for our studies (mcd4-174) harbors a single amino acid change in motif 2. The mcd4-174 mutant (1) is defective in ER-to-Golgi transport of GPI-anchored proteins (i.e., Gas1p) while other proteins (i.e., CPY) are unaffected; (2) secretes and releases (potentially up-regulated cell wall) proteins into the medium, suggesting a defect in cell wall integrity; and (3) exhibits marked morphological defects, most notably the accumulation of distorted, ER- and vesicle-like membranes. mcd4-174 cells synthesize all classes of inositolphosphoceramides, indicating that the GPI protein transport block is not due to deficient ceramide synthesis. However, mcd4-174 cells have a severe defect in incorporation of [3H]inositol into proteins and accumulate several previously uncharacterized [3H]inositol-labeled lipids whose properties are consistent with their being GPI precursors. Together, these studies demonstrate that MCD4 encodes a new, conserved component of the GPI anchor synthesis pathway and highlight the intimate connections between GPI anchoring, bud emergence, cell wall function, and feedback mechanisms likely to be involved in regulating each of these essential processes. A putative role for Mcd4p as participating in the modification of GPI anchors with side chain phosphoethanolamine is also discussed.  (+info)

Effects of beta2-adrenergic stimulation on single-channel gating of rat cardiac L-type Ca2+ channels. (7/1992)

Cardiac L-type Ca2+ channels can be stimulated by activation of beta2-adrenoceptors. We intended to determine how the gating behavior at the single-channel level (cell-attached configuration) is affected after selective stimulation of beta2-adrenoceptors. Rat cardiomyocytes were exposed to zinterol, a beta2-agonist (n = 7), isoproterenol (n = 6), a nonselective agonist, 8-bromo-cAMP (n = 6), and a combination of isoproterenol and ICI-118551 (n = 8), a selective beta2-receptor antagonist, or isoproterenol and CGP-20712A, a beta1-selective antagonist (n = 7). In all groups the ensemble-average current and the availability of the channels to open on depolarization were increased in a similar fashion. In addition, the open probability (Po) within active sweeps was elevated. However, zinterol exerted this effect in a unique manner. It elevated Po not by shortening closed times but solely by reducing active sweeps with very low Po and a short burst duration. All zinterol effects were abolished by ICI-118551 (n = 5) and mimicked by isoproterenol plus CGP-20712A (n = 7). We conclude that beta2-adrenoceptor activation of L-type channels differs qualitatively from the classical cAMP-dependent mechanism.  (+info)

A randomized, double-blind, comparative trial of a new oral combination of artemether and benflumetol (CGP 56697) with mefloquine in the treatment of acute Plasmodium falciparum malaria in Thailand. (8/1992)

CGP 56697, a new oral fixed combination of artemether and benflumetol, was tested in a double-blinded, randomized trial in 252 adult patients treated either with CGP 56697 (4 x 4 tablets each containing 20 mg of artemether and 120 mg of benflumetol, given at 0, 8, 24, and 48 hr), or with mefloquine (three tablets of 250 mg at initial diagnosis, followed by two tablets of 250 mg at 8 hr). Baseline data of the two groups were comparable. The 28-day cure rate with CGP 56697 was lower than with mefloquine (69.3% versus 82.4%; P = 0.002). However, CGP 56697 was more effective than mefloquine in parasite clearance time (43 hr versus 66 hr; P < 0.001) fever clearance time (32 hr versus 54 hr; P < 0.005), and gametocyte clearance time (152 hr versus 331 hr; P < 0.001). This study revealed that CGP 56697 is effective against multidrug-resistant Plasmodium falciparum malaria in Thailand, but higher doses will probably be needed to improve the cure rate.  (+info)

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Background The inhaled corticosteroid (ICS) fluticasone propionate (fluticasone) and the long-acting β2-agonist (LABA) formoterol fumarate (formoterol) are being made available as a combination...
Bronchodilators - long-acting b2-adrenergic agonists (formoterol and salmeterol) and a long-acting antimuscarinic drug (tiotropium), are the main drugs applied in symptomatic treatment of COPD. In patients with COPD, dyspnea is frequently associated with simple everyday activities. Two questionnaires have been published recently as a means of assessing the patients ability to perform morning activities and symptoms. Dynamic hyperinflation is the pathophysiological disorder responsible for dyspnea and decreased exercise tolerance in COPD. Formoterol is faster than salmeterol in diminishing air-trapping. It has been shown that treatment with formoterol and tiotropium in COPD patients improves FEV1, FVC, IC, symptoms score and quality of life in comparison with tiotropium applied alone. Among LABA and inhaled glucocorticosteroids combinations, those containing formoterol have a more beneficial effect on the ability to perform simple morning activities (budesonide/formoterol was better than ...
Pirbuterol (trade name Maxair) is a short-acting β2 adrenoreceptor agonist with bronchodilating action used in the treatment of asthma, available (as pirbuterol acetate) as a breath-activated metered-dose inhaler (Maxair Autohaler). Pirbuterol is used in asthma for reversal of acute bronchospasm, and also as a maintenance medication to prevent future attacks. It should be used in patients 12 years of age and older with or without concurrent theophylline and/or inhaled corticosteroid. After inhalation of doses up to 800 μg (twice the maximum recommended dose) systemic blood levels of pirbuterol are below the limit of assay sensitivity (2-5 ng/ml). A mean of 51% of the dose is recovered in urine as pirbuterol plus its sulfate conjugate following administration by aerosol. Pirbuterol is not metabolized by catechol-O-methyltransferase. The plasma half-life measured after oral administration is about two hours. Maxair Autohaler (pirbuterol acetate inhalation aerosol) For Oral Inhalation Only. U.S. ...
Title:Biosynthetic Pathways of Bioactive N-Acylethanolamines in Brain. VOLUME: 12 ISSUE: 1. Author(s):Kazuhito Tsuboi, Natsuki Ikematsu, Toru Uyama, Dale G. Deutsch, Akira Tokumura and Natsuo Ueda. Affiliation:Department of Biochemistry, Kagawa University School of Medicine, 1750-1 Ikenobe, Miki, Kagawa 761-0793, Japan.. Keywords:N-Acylethanolamine, anandamide, biosynthesis, NAPE-PLD, oleoylethanolamide, palmitoylethanolamide, phospholipid, plasmalogen. Abstract:Ethanolamides of long-chain fatty acids are a class of endogenous lipid mediators generally referred to as Nacylethanolamines (NAEs). NAEs include anti-inflammatory and analgesic palmitoylethanolamide, anorexic oleoylethanolamide, and the endocannabinoid anandamide. Since the endogenous levels of NAEs are principally regulated by enzymes responsible for their biosynthesis and degradation, these enzymes are expected as targets for the development of therapeutic agents. Thus, a better understanding of these enzymes is indispensable. The ...
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Formoterol, also known as eformoterol, is a long-acting β2 agonist (LABA) used as a bronchodilator in the management of asthma and chronic obstructive pulmonary disease (COPD). Formoterol has an extended duration of action (up to 12 h) compared to short-acting β2 agonists such as salbutamol (albuterol), which are effective for 4 h to 6 h. LABAs such as formoterol are used as symptom controllers to supplement prophylactic corticosteroid therapy. A reliever short-acting β2 agonist (e.g., salbutamol) is still required, since LABAs are not recommended for the treatment of acute asthma. It was patented in 1972 and came into medical use in 1998.[2] It is also marketed in the combination formulations budesonide/formoterol and mometasone/formoterol. ...
Background: The change from pre-dose FEV1 at day 1 to 2-hours post-dose FEV1 at week 12 was used as a co-primary spirometric outcome in the development of fluticasone/formoterol combination therapy (FLUT/FORM; flutiform®) in the pivotal studies. As this endpoint is not well characterised in the literature, we investigated its utility by examining the relationship with other spirometric and non-spirometric indices, including the change from pre-dose FEV1 at day 1 to pre-dose FEV1 at week 12 and FEV1 AUC0-12 at week 12 (area under the FEV1 curve over 0-12 hrs post-dose at week 12).. Methods: FEV1 and AUC endpoint data from 3 randomised, double-blind, 12-week studies comparing FLUT/FORM pMDI to fluticasone pMDI were pooled, and Pearsons correlation coefficient (R) or odds ratios were calculated.. Results and Conclusions: Change from pre-dose FEV1 at day 1 to 2h post-dose FEV1 at week 12 assesses both chronic ICS-mediated anti-inflammatory and acute LABA bronchodilatory effects. This endpoint ...
Pirbuterol is a beta-2 adrenergic bronchodilator. In vitro studies and in vivo pharmacologic studies have demonstrated that pirbuterol has a preferential effect on beta-2 Adrenergic receptors compared with isoproterenol. While it is recognized that beta-2 adrenergic receptors are the predominant receptors in bronchial smooth muscle, data indicate that there is a population of beta-2 receptors in the human heart, existing in a concentration between 10-50%. The precise function of these receptors has not been established. The pharmacologic effects of beta adrenergic agonist drugs, including pirbuterol, are at least in proof attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (AlP) to cyclic-3† ,5†-adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells,
Triethanolamine poisoning symptoms, causes, diagnosis, and treatment information for Triethanolamine poisoning (Chemical poisoning - Triethanolamine) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention, and prognosis.
The identification of biomarkers indicating the level of aggressiveness of prostate cancer (PCa) will address the urgent clinical need to minimize the general overtreatment of patients with non-aggressive PCa, who account for the majority of PCa cases.
여기서는 활동 기반 프로브의 제조 및 사용을 설명 (ARN14686, 운데 10 ynyl- N - [(3- S) -2- oxoazetidin -3- 일] 카르 바 메이트)의 검출 및 정량화를 허용 염증성 효소 ...
These RCTs had limitations, as they involved selected patients who received careful follow-up, and some trials were of short duration (12 weeks). One death in the salmeterol trials and eight in the formoterol trials limited the ability to measure risk for this outcome. In the study of Sears and Radner [16], statistical issues prevent the proposition of a definite conclusion. Finally, there are pitfalls in meta-analyses of RCTs [17].. Two recent Cochrane meta-analyses assessed the safety of salmeterol and formoterol. In adults, by comparison with placebo, an increased risk of serious adverse events was found with regular formoterol, and this was not abolished in patients taking ICS [18]. The authors conclude that data on all-cause serious adverse events should be more fully reported in journal articles, and not combined with all severities of adverse events or limited to those events that are thought by the investigator to be drug-related [18]. The discrepancies between the Sears and Radner [16] ...
Oxis turbohaler contains the bronchodilator formoterol, it is used on a regular basis in asthma and COPD to keep your airways open, information about using this formoterol inhaler
Generic symbicort coming, formoterol canada sans ordonnance The delivery will be organized as promptly as practicable. Generic Meds for your family - ORDER NOW! At the moment our online pharmacy is on
Triethanolamine acetate | C8H19NO5 | CID 159752 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Learn more about Triethanolamine. We enable science by offering product choice, services, process excellence and our people make it happen.
Easy-to-read patient leaflet for Formoterol Capsules for Inhalation. Includes indications, proper use, special instructions, precautions, and possible side effects.
Creative-Proteomics offer cas 54239-37-1 Cimaterol. We are specialized in manufacturing Stabel Isotope Labeled Analytical Standard products.
Variations in N-acylethanolamines (NAE) levels are associated with obesity and metabolic comorbidities. Their role in the gut… Expand ...
EWGs Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases.
Import patch from Debian http://bugs.debian.org/347650 which hacks around libtool deplib re-ordering, which inhibits -Wl,--as-needed. You have to set -Wl,--as-needed seperately in LDFLAGS for this to do any good, -Wl,--as-needed,--something-else will not do, but you can set -Wl,--something-else afterwards. Also make sure eclasses I own run elibtoolize so they can reap the benefit ...
The olfactory function shows a temporary decline following open rhinoplasty but tends to revert to its preoperative levels 6 months post surgery. This may be a reassuring answer to candidates for this kind of nasal surgery since they are likely to inquire whether the loss or decrease in their sense of smell is reversible, and, if reversible, how long it is before their sense of smell is normal again [24].. One week after open rhinoplasty, anosmia was present in 87.5% of our patients, and the rest exhibited moderate to severe hyposmia. In other words, almost all the patients were anosmic shortly after open rhinoplasty. By postoperative week 6, however, anosmia had downgraded to mainly mild to moderate levels of hyposmia. All our patients had regained their preoperative olfactory function levels by postoperative month 6; most were normosmic and a few were mildly hyposmic.. In a study of 93 patients undergoing various types of nasal surgery, including ethmoidectomy, polypectomy, Caldwell-Luc ...
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In this study it was demonstrated that a 6-week treatment regimen with inhalation of a combination of budesonide and formoterol on demand was superior to on-demand inhalation of a SABA in reducing EIB, assessed by an exercise test performed after a 24 h period free from any medication. Furthermore, the reduction in EIB after 6 weeks of treatment with inhaled budesonide/formoterol on demand was non-inferior to daily inhalation of budesonide. This finding clearly indicates that treatment with three to four doses per week of the combination is sufficient to provide good asthma control, implying no need for regular treatment with inhaled corticosteroids (ICS) in patients with mild asthma.. According to current guidelines, patients with EIB should inhale a rapid-acting β2 agonist prior to exercise and if reliever medication is needed more than twice a week, regular controller therapy with ICS should be considered.1 Our study included patients with mild asthma in whom inhaled steroids were not ...
This randomised, double-blind, 6-month study compared budesonide/formoterol for maintenance and relief with salmeterol/fluticasone and a fixed maintenance dose of budesonide/formoterol, both with terbutaline for relief. Following a 2-week run-in, 3335 symptomatic adults and adolescents (mean FEV1 73 …
A large-scale study of asthma maintenance and relief medication showed that treatment with budesonide/formoterol maintenance and reliever therapy is more effective in reducing asthma exacerbations than fixed doses of budesonide/formoterol or salmeterol/fluticasone. The 6-month-long, double-blind study, which included 3335 patients with asthma, compared the safety and efficacy of budenoside/formoterol when used for both maintenance and reliever therapy. Patients were randomized into 3 groups: one group received 25/125 mcg salmeterol/fluticasone, 2 inhalations bid, plus terbutaline as a reliever; the second group received 320/9 mcg budesonide/formoterol, one inhalation bid, plus terbutaline as a reliever; and the third group received 160/4.5 mcg budesonide/formoterol, one inhalation bid, plus budesonide/formoterol as a reliever. Patients who took budesonide/formoterol as a maintenance drug and as a reliever used at least 25% less inhaled corticosteroid than those patients on a fixed dose of ...
INTRODUCTION: In budesonide/formoterol (Symbicort(R) Turbuhaler(R), AstraZeneca, Lund, Sweden) maintenance and reliever therapy (SMART), patients with asthma take a daily maintenance dose of budesonide/formoterol, with the option of taking additional doses for symptom relief instead of a short-acting beta(2)-agonist (SABA). This study assesses the cost-effectiveness of SMART compared with usual care in patients with mild-to-moderate persistent asthma treated by general practitioners in the Netherlands from a societal perspective. METHODS: The study was linked to a randomized, active-controlled, open-label, multicenter, 12-month clinical trial, with a prospective collection of resource use. One hundred and two patients ,/=18 years with mild-to-moderate persistent asthma and daily inhaled corticosteroids (ICS) prior to the trial were included. SMART was given as two inhalations of budesonide/formoterol (100/6 mug) once daily, plus additional doses as needed. The control group was treated according ...
Chemotherapy remains an important approach in the fight against malaria. Artemether-lumefantrine combination is widely in use due to its effectiveness against Plasmodium falciparum. Misuse in the form of multiple repeated doses of this anti-malaria drug is rampant in Nigeria. This study was designed to assess the hepatotoxic and clastogenic potential of extreme misuse of artemether-lumefantrine in rats. Graded doses of artemether-lumefantrine (1-5 mg/kg body weight) were administered by oral gavage for 6 weeks, twice daily, for 3 consecutive days per week. Artemether-lumefantrine, at all doses, did not have significant effects on the body and relative liver weight of treated group compared to the negative control group. The mean γ-glutamyltransferase, alanine, and aspartate aminotransaminase activity in groups of artemether-lumefantrine treated rats were significantly higher (p , 0.05) than that of the negative control group indicating that repeated administration of artemether-lumefantrine may ...
Budesonide/Formoterol Teva is a medicine that contains the active substances budesonide and formoterol. It is used for the treatment of asthma in adults for whom a combination product is considered appropriate. It can be used in patients whose disease is not adequately controlled by treatment with other asthma medicines called corticosteroids and short-acting beta-2 agonists taken by inhalation, or in patients whose disease is adequately controlled by treatment with corticosteroids and long-acting beta-2 agonists taken by inhalation.. Budesonide/Formoterol Teva is also used to relieve the symptoms of severe chronic obstructive pulmonary disease (COPD) in adults who have had exacerbations (flare-ups) of the disease in the past despite regular treatment. COPD is a long-term disease in which the airways and air sacs inside the lungs become damaged or blocked, leading to difficulty in breathing.. Budesonide/Formoterol Teva is a hybrid medicine. This means that it is similar to a reference ...
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Health, ...Wilmington DE May 20 2008 A new open-label study evaluated patient...Results showed that patients receiving budesonide/formoterol combinati...These data showed that patients treated with budesonide/formoterol com......,New,patient,satisfaction,study,with,budesonide/formoterol,combination,therapy,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
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The rapid effects of budesonide plus formoterol in patients with obstructive airway diseases Hulya Bayiz,1 Sevket Ozkaya,1 Adem Dirican,2 Ferah Ece1 1Department of Pulmonary Medicine, Faculty of Medicine, Bahcesehir University, Istanbul, 2Department of Pulmonary Medicine, Samsun Medical Park Hospital, Samsun, Turkey Introduction: The use of a combination inhaler containing budesonide and formoterol (BUD/FOR) to both maintenance and quick relief therapy has been recommended as an improved method of using inhaled corticosteroid/long-acting β agonist therapy. The aim of this study was to investigate the acute effects of BUD/FOR and testing the availability of BUD/FOR for early reversibility test in patients with airway obstruction. Patients and methods: The study was conducted on patients who were admitted to the Department of Pulmonary Medicine, Samsun Medical Park Hospital, Samsun, Turkey. Results: A total of 44 patients were included in the study. The mean age of patients was 48.5±17.3 (range
This study is investigating the efficacy of tiotropium bromide with and without budesonide/formoterol in the perioperative period in non-small cell lung cancer
Review data showing FEV1 and lung function in COPD patients using SYMBICORT 160/4.5 (budesonide/formoterol fumarate dihydrate) Inhalation Aerosol, and the adverse reactions found in COPD clinical studies.
Formoterol a budezonid, Inhalačný prášok, ATC R03AK07, SPC (Súhrn údajov o prípravku) Terapeutické indikácie: Budesonide/Formoterol Teva Pharma B.V. je indikovaný len u dospelých vo veku 18 rokov a viac. Astma Budesonide/Formoterol Teva Pharma B.V. je indikovaný na pravidelnú liečbu astmy v prípadoch, kedy je vhodné použiť kombináciu (inhalačného kortikosteroidu a dlhodobo pôsobiaceho agonistu β2- adrenoreceptora): u pacientov, u ktorých sa podávaním inhalačných kortikosteroidov a „podľa potr...
Clinical Effectiveness of Budesonide/Formoterol Fumarate Easyhaler®, for Patients with Poorly Controlled Obstructive Airway Disease: a Real-World Study of Patient-Reported Outcomes
BUDESONIDE is a steroid that reduces inflammation in the body. Formoterol is a bronchodilator that relaxes muscles in the airways to improve breathing. Budesonide and Formoterol is used to prevent bronchospasm in people with asthma or chronic obstructive pulmonary disease (COPD).. Generic Symbicort (Budesonide Formoterol 100mcg + 6/160mcg + 4.5/200mcg + 6/400mcg + 6mcg) $ 24.98 pill - Anti-inflammatories, Asthma @ MyMedsBuy.com - Official Drug Store Online. buy viagra online
BUDESONIDE is a steroid that reduces inflammation in the body. Formoterol is a bronchodilator that relaxes muscles in the airways to improve breathing. Budesonide and Formoterol is used to prevent bronchospasm in people with asthma or chronic obstructive pulmonary disease (COPD).. Generic Symbicort (Budesonide Formoterol 100 Mcg + 6/160 Mcg + 4.5/200 Mcg + 6/400 Mcg + 6 Mcg) # Your Online Doctor @ Online shop. Online shopping like never before! Get the latest trends ruling the charts in WorldWide. With the most greatest range of pharmacy!
Budesonide / formoterol causes indigestion and sedation in many people, along with anticholinergic side effects. Since Budesonide / formoterol may cause for fainting, avoid skates, skateboards, bicycles and enjoyed driving after taking this medicine. Proventil and altogether normal saline in reducing fainting after spinal anesthesia in cesare
Budesonide/Formoterol Teva is a medicine available in a number of countries worldwide. A list of US medications equivalent to Budesonide/Formoterol Teva is available on the Drugs.com website.
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Patients with mild to moderate asthma only need relief treatment. In this study, patients taking the combination of budesonide/formoterol (Symbicort) as needed had slightly fewer severe exacerbations than patients treated with twice daily budesonide (Pulmicort).
The use of a combination inhaler containing budesonide and formoterol as both maintenance and quick relief therapy (SMART) has been recommended as an improved method of using inhaled corticosteroid/long-acting β agonist (ICS/LABA) therapy. Published double-blind trials show that budesonide/formoterol therapy delivered in SMART fashion achieves better asthma outcomes than budesonide monotherapy or lower doses of budesonide/formoterol therapy delivered in constant dosage. Attempts to compare budesonide/formoterol SMART therapy with regular combination ICS/LABA dosing using other compounds have been confounded by a lack of blinding and unspecified dose adjustment strategies. The asthma control outcomes in SMART-treated patients are poor; it has been reported that only 17.1% of SMART-treated patients are controlled. In seven trials of 6-12 months duration, patients using SMART have used quick reliever daily (weighted average 0.92 inhalations/day), have awakened with asthma symptoms once every 7-10 ...
Symbicort is the aerosol mixture of budesonide and formoterol. It is an aerosol spray inhaled orally. Budesonide is a corticosteroid which is used to reduce inflammation. Formoterol is a slow-acting bronchodilator used for opening the bronchioles to assist respiration.
Site:mysymbicort.com Coupon Code . SYMBICORT combines an ICS, budesonide and a LABA medicine, formoterol. LABA medicines, such as formoterol, when used alone can increase the risk of ho...
Asthma: Reliever medications. Fast-acting bronchodilators are reliever medications (also called rescue medications) used as needed to relieve acute asthma symptoms (asthma attacks) and to prevent asthma symptoms caused by exercise. They act quickly, but most act only for short periods of time. When your asthma gets worse, your doctor may recommend that you temporarily increase the amount of rescue medication youre taking.
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Symbicort (budesonide and formoterol) is used to prevent bronchospasm in people with asthma or COPD. Includes Symbicort side effects, interactions and indications. Also: Online symbicort bestellen forum, Mail order symbicort mastercard usa, Generic symbicort order shop usa, Getting symbicort in canada, Generic symbicort compendium, Where to buy symbicort uk, Symbicort online kopen, Order generic symbicort mastercard
Large clinical trials have confirmed the long-term efficacy of inhaled corticosteroid/long-acting β2-agonist combinations in patients with chronic obstructive pulmonary disease (COPD). It was hypothesized that significant treatment effects would already be present within 3 months after the initiation of treatment across a range of clinical outcomes, irrespective of COPD severity.Post hoc analysis of 3-month post-randomization outcomes, including exacerbation rates, dropouts, symptoms, reliever use, and lung function, from three studies with similar inclusion criteria of moderate-to-very-severe COPD. Patients (n=1,571) were treated with budesonide/formoterol (B/F) 320/9 μg or placebo, twice daily; in one study, tiotropium 18 μg once daily was also given.Over the first 3 months of treatment, fewer patients randomized to B/F experienced exacerbations versus the placebo group (111 and 196 patients with ≥1 exacerbation, respectively). This was true in each COPD severity group. Compared with ...
Nebivolol is administered as a racemic mixture of equal proportions of d and l isomers. Nebivolol has 4 asymmetric centres, d-isomer refers to (S,R,R,R)-nebivolol and l-isomer to (R,S,S,S)-nebivolol. Antihypertensive effects of nebivolol appear to be greater with both isomers than with the d-isomer alone. Nebivolol exhibits greater degree of beta 1/beta 2-receptor selectivity compared with other commonly used beta-blockers.. The selectivity of Nebivolol on the beta 1-adrenergic receptor is 321-fold higher than for beta 2-adrenergic receptor. Conventional beta blockers are associated with unfavorable effects on metabolic parameters. Nebivolol has favorable metabolic profile, with no deleterious effect on insulin sensitivity which may result from its agonistic activity on the beta 3 adrenoreceptor. This beta blocker exhibits anti-proliferative and antioxidant properties [7].. The efficacy and tolerability of nebivolol have been evaluated in comparison with placebo and other beta-blockers ...
View the possible side effects of DULERA® (mometasone furoate and formoterol fumarate dihydrate) and read the Selected Important Safety Information about DULERA.
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Official patient Web site for SYMBICORT, a medicine for the treatment of asthma and COPD. Find information about the inhaler and side effects
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WASHINGTON - The FDA approved a new triple therapy (Breztri Aerosphere) as a maintenance treatment for patients for adults with chronic obstructive pulmonary disease (COPD).. This combination, which is a single-inhaler, fixed dose therapy indicated for oral inhalation - two inhalations, taken two times a day - contains budesonide, an inhaled corticosteroid (ICS); glycopyrrolate, a long-acting muscarinic antagonist (LAMA); and formoterol fumarate, a long-acting beta2-agonist (LABA).. This approval was based on results from the phase III ETHOS trial, which pitted the triple therapy against a pair of dual therapy regimens - glycopyrrolate/formoterol fumarate and budesonide/formoterol fumarate - at doses of 320μg and 160μg. The ETHOS investigators reported that, at both doses, the triple therapy bested both dual therapies in significantly reducing COPD exacerbations, as previously reported by BreakingMED. The approval was also supported by results from the phase III KRONOS trial, which was ...
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To use Symbicort inhaler patients should follow next steps:. 1. Take your Symbicort out of the moisture-protective foil pouch before you use it for the first time and throw the foil away. Write the date that you open the foil pouch on the box.. 2. A counter is attached to the top of the metal canister. The counter will count down each time you release a puff of Symbicort. The arrow points to the number of inhalations (puffs) left in the canister. The counter will stop counting at zero (0).. 3. Use the Symbicort canister only with the red Symbicort inhaler supplied with the product. Parts of the Symbicort inhaler should not be used with parts from any other inhalation product.. 4. Shake your Symbicort inhaler well for 5 seconds right before each use. Remove the mouthpiece cover by squeezing gently at both sides, then pulling out. Check the mouthpiece for foreign objects before use.. 5. Before you use Symbicort for the first time, you will need to prime it. To prime Symbicort, hold it in the ...
The BP-lowering effects of nebivolol are well established.13,27,28 The seminal and novel finding of the present study, however, is that in addition to, and independent of, lowering BP, nebivolol markedly and favorably affects ET-1 system activity. Indeed, the results reported herein demonstrate that (1) chronic nebivolol, but not metoprolol, therapy reduces ET-1-mediated vasoconstrictor tone in adults with elevated BP and (2) reductions in ET-1 vasoconstriction underlie nebivolol-induced improvements in endothelium-dependent vasodilation. Diminished ET-1-mediated vasoconstrictor tone may represent an important endovascular pleiotropic effect of nebivolol, contributing to its favorable effect on overall cardiovascular risk.29. In this study, there was a similar and significant (≈30%) increase in FBF responses to selective ETA receptor blockade in all 3 groups before treatment. In addition, nonselective ETA/B receptor blockade resulted in a further increase (≈35%) in FBF in all the groups. ...
The study will be a 12 week treatment (84 days), parallel group, randomized, double blind, double dummy, study to assess the superiority of indacaterol (150 μg o.d.) versus formoterol (12 μg b.i.d.) in terms of trough forced expiratory volume in 1 second (FEV1).. Patients will be enrolled after giving informed consent and then begin a screening/run-in period for 14 days. Patients will be randomized to one of two treatment groups using an allocation ratio of 1:1 to receive either indacaterol (150 μg o.d.) and placebo to formoterol, or formoterol (12 μg b.i.d.) and placebo to indacaterol for a treatment period of 12 weeks. ...
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"Ethanolamines and Propanolamines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007. ...
Frauenkron, Matthias; Melder, Johann-Peter; Ruider, Günther; Rossbacher, Roland; Höke, Hartmut (2001). "Ethanolamines and ...
Ethanolamines Aminomethyl propanol Heptaminol Isoetarine Propanolamines Sphingosine Methanolamine (simplest amino alcohol) ... "Ethanolamines and Propanolamines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007. ...
Frauenkron, Matthias; Melder, Johann-Peter; Ruider, Günther; Rossbacher, Roland; Höke, Hartmut (2001). "Ethanolamines and ...
"Ethanolamines and Propanolamines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007. ... Lessmann, H.; Uter, W.; Schnuch, A.; Geier, J. (2009). "Skin sensitizing properties of the ethanolamines mono-, di-, and ... Triethanolamine is produced from the reaction of ethylene oxide with aqueous ammonia, also produced are ethanolamine and ... Complexometric titration Ethanolamine Ethanol Triethanolamine salicylate "Front Matter". Nomenclature of Organic Chemistry : ...
Choline Diphenhydramine Doxylamine Ethanolamine Meclofenoxate Orphenadrine Littel, RJ; Bos, M; Knoop, GJ (1990). "Dissociation ... Matthias Frauenkron, Johann-Peter Melder, Günther Ruider, Roland Rossbacher, Hartmut Höke (2002). "Ethanolamines and ...
... or phosphoethanolamine is an ethanolamine derivative that is used to construct two different categories ...
Ethanolamine Oleate (Ethanolamin) injection is indicated for the treatment of patients with esophageal varices that have ... "Ethanolamine Oleate". RXList. Retrieved 7 March 2020. CS1 maint: discouraged parameter (link) v t e. ...
"Syntheses from Ethanolamine. V. Synthesis of Δ2-Oxazoline and of 2,2'-Δ2-Dioxazoline". Journal of the American Chemical Society ...
These amides conceptually can be formed from a fatty acid and ethanolamine with the release of a molecule of water, but the ... The hydrolysis of NAE to free fatty acid (FFA) and ethanolamine (MEA) in animals, is catalyzed by fatty acid amide hydrolase ( ... NAE 20:4 (AEA: C22H37NO2; 20:4, ω-6) is the amide of arachidonic acid (C20H32O2; 20:4, ω-6) and ethanolamine (MEA: C2H7NO). NAE ... N-Palmitoylethanolamine (PEA: C18H37NO2; 16:0) is the amide of palmitic acid (C16H32O2; 16:0) and ethanolamine. It is a ligand ...
O-Arachidonoyl ethanolamine is arachidonic acid and ethanolamine joined by an ester linkage, the opposite of the amide linkage ... Virodhamine (O-arachidonoyl ethanolamine; O-AEA) is an endocannabinoid and a nonclassic eicosanoid, derived from arachidonic ...
... is the ethanolamine salt of the hydroxamic acid derivative piroctone. It is often used in anti-dandruff ... Piroctone olamine (INN; also known as piroctone ethanolamine; brand name Octopirox) is a compound sometimes used in the ...
Methanol Methylamine Ethanolamine (2-aminoethanol) Pubchem. "Methanolamine". pubchem.ncbi.nlm.nih.gov. Retrieved 2019-01-05. ...
This forms ethanolamine phosphate and hexadecenal. Sphingolipids are commonly believed to protect the cell surface against ... The sphingosine backbone is O-linked to a (usually) charged head group such as ethanolamine, serine, or choline.[citation ...
It has an advantage over a similar amine, ethanolamine, in that a higher concentration may be used for the same corrosion ... Matthias Frauenkron, Johann-Peter Melder, Günther Ruider, Roland Rossbacher, Hartmut Höke "Ethanolamines and Propanolamines" in ... The reaction of ethylene oxide with aqueous ammonia first produces ethanolamine: C2H4O + NH3 → H2NCH2CH2OH which reacts with a ... "Skin sensitizing properties of the ethanolamines mono-, di-, and triethanolamine. Data analysis of a multicentre surveillance ...
"Ethanolamine Compounds (MEA, DEA, TEA And Others)". Safe Cosmetics. Retrieved 2020-06-17. "tetraethylammonium , Ligand page , ...
The copper in the preparation is in the form of a soluble complex with ammonia NH 3 or an amine such as ethanolamine N(C 2H 5)H ... The formulations with ethanolamine, especially ACQ-D, are generally used for easier woods (such as southern pine) because it ... Otherwise ethanolamine is preferred as copper carrier. Quaternary ammonium cations The quaternary ammonium cation in some ... Types registered in the US and Canada: ACQ-A: copper-ethanolamine (50% CuO equivalent), and DDA chloride (50%). ACQ-B: copper- ...
... phosphatidylethanolamine is also made via the cytidine diphosphate-ethanolamine pathway, using ethanolamine as the substrate. ... Whereas the phosphate group is combined with choline in phosphatidylcholine, it is combined with the ethanolamine in ... N-Acylphosphatidylethanolamine Phosphatidyl ethanolamine methyltransferase Wellner, Niels; Diep, Thi Ai; Janfelt, Christian; ... They are synthesized by the addition of cytidine diphosphate-ethanolamine to diglycerides, releasing cytidine monophosphate. S- ...
The poly(methyl-ethanolamine) formed by further addition of ethylene oxide to methylethanolamine remains in the distillation ... Ltd.: Methyl Ethanolamines Technology Archived 2016-03-06 at the Wayback Machine (PDF; 152 kB). Product Safety Assessment, DOW ... Ethanolamine Dimethylethanolamine Merck Index, 12th Edition, 6096. Matthias Frauenkron, Johann-Peter Melder, Günther Ruider, ... where it is used together with its analogs ethanolamine and dimethylethanolamine. N-Methylethanolamine is produced industrially ...
It is degraded primarily by the fatty acid amide hydrolase (FAAH) enzyme, which converts anandamide into ethanolamine and ... "N-Acylation of ethanolamine phospholipids in canine myocardium". Biochim. Biophys. Acta. 712 (2): 342-55. doi:10.1016/0005-2760 ... which breaks it down into free arachidonic acid and ethanolamine. Studies of piglets show that dietary levels of arachidonic ...
Treatment with ethanolamine ends up making an aminoetylborinate. 2-Aminoethoxydiphenyl borate (2-APB) inhibits transient ...
Petrosino S, Iuvone T, Di Marzo V (June 2010). "N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities". ... June 2005). "Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: ... June 2005). "Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: ...
α-aryloxy-benzyl derivatives of ethanolamine and morpholine". Eur J Med Chem. 3: 235-242.. ...
α-aryloxy-benzyl derivatives of ethanolamine and morpholine". Eur J Med Chem. 3: 235-242. "Farmitalia bought by Kabi Pharmacia ...
Spanner S, Ansell GB (1979). "Choline kinase and ethanolamine kinase activity in the cytosol of nerve endings from rat ... Spanner S, Ansell GB (1978). "Choline and ethanolamine kinase activity in the cytoplasm of nerve endings from rat forebrain". ... The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms ...
The fatty amides include N-acyl ethanolamines, such as the cannabinoid neurotransmitter anandamide. Glycerolipids are composed ...
Urquhart, P; Wang, J; Woodward, D. F.; Nicolaou, A (2015). "Identification of prostamides, fatty acyl ethanolamines, and their ...
In nature, many FAAs have ethanolamine as the amine component. Also known as N-acylethanolamines, they contain the ...
... s are chemical compounds which are amides formed from carboxylic acids and ethanolamine. Some ethanolamides are ... Ethanolamides can be prepared synthetically by heating esters with ethanolamine. Diethanolamide Docosatetraenoylethanolamide ...
Anandamide was the first such compound identified as arachidonoyl ethanolamine. The name is derived from the Sanskrit word for ... A fifth endocannabinoid, virodhamine, or O-arachidonoyl-ethanolamine (OAE), was discovered in June 2002. Although it is a full ...
... has role mouse metabolite (CHEBI:75771) ethanolamine (CHEBI:16000) is a ethanolamines (CHEBI:23981) ... ethanolamine (CHEBI:16000) is a primary alcohol (CHEBI:15734) ethanolamine (CHEBI:16000) is a primary amine (CHEBI:32877) ... ethanolamine (CHEBI:16000) has role Escherichia coli metabolite (CHEBI:76971) ethanolamine (CHEBI:16000) has role human ... β-D-Manp-(1→2)-β-D-Manp-(1→2)-α-D-Manp-O[CH2]2NH2 (CHEBI:78888) has functional parent ethanolamine (CHEBI:16000). β-D-Manp-(1→2 ...
Ethanolamine is biosynthesized by decarboxylation of serine: HOCH2CH(CO2H)NH2 → HOCH2CH2NH2 + CO2 Ethanolamine is the second- ... The ethanolamines comprise a group of amino alcohols. A class of antihistamines is identified as ethanolamines, which includes ... Ethanolamine is a colorless, viscous liquid with an odor reminiscent of ammonia. Its derivatives are widespread in nature; e.g ... Ethanolamine is often used for alkalinization of water in steam cycles of power plants, including nuclear power plants with ...
Media in category "Ethanolamine". The following 8 files are in this category, out of 8 total. ... Category:Ethanolamines (en); تصنيف:أمينات الإيثانول (ar); Kategori:Etanolaminler (tr) categoría de Wikimedia (es); категория на ... Retrieved from "https://commons.wikimedia.org/w/index.php?title=Category:Ethanolamine&oldid=416225745" ...
In enzymology, an ethanolamine kinase (EC 2.7.1.82) is an enzyme that catalyzes the chemical reaction ATP + ethanolamine ⇌ {\ ... Other names in common use include ethanolamine kinase (phosphorylating), and ethanolamine phosphokinase. This enzyme ... Sung CP, Johnstone RM (1967). "Phosphorylation of choline and ethanolamine in Ehrlich ascites-carcinoma cells". Biochem. J. 105 ... Weinhold PA, Rethy VB (1972). "Ethanolamine phosphokinase: activity and properties during liver development" (PDF). Biochim. ...
2-Aminoethanol, β-Aminoethyl alcohol, Ethylolamine, 2-Hydroxyethylamine, Monoethanolamine Colorless, viscous liquid or solid (below 51°F) with an unpleasant, ammonia-like odor.
Decomposes on heating and on burning. This produces toxic and corrosive gases including nitrogen oxides. The substance is a medium strong base. Reacts with cellulose nitrate. This generates fire and explosion hazard. Reacts violently with strong acids and strong oxidants. Attacks copper, aluminium, their alloys and rubber ...
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... Growth, Trends, and Forecast 2016 ? 2024 - published on openPR. ... Ethanolamines Market - Global Industry Insights 2025 Ethanolamines - Insights Ethanolamines are colorless, viscous organic ... Ethanolamines Market Trends,Outlook And Key Opportunities 2024 The top five companies in the global ethanolamines market - The ... Ethanolamines Market Expansion Projected to Gain an Uptick During 2021 Ethanolamine, also known as 2-aminoethanol or ...
This report presents a comprehensive overview of the ethanolamines market in Slovenia and a forecast for its development in the ... Structure of the ethanolamines market in Slovenia by origin in value terms in the last 5 years. Structure of the ethanolamines ... Structure of the ethanolamines market in Slovenia in the last 5 years, in value terms. Structure of the ethanolamines market in ... Structure of the ethanolamines market in Slovenia in the last 5 years, in value terms. Structure of the ethanolamines market in ...
ethanolamine ammonia-lyase small subunit [Psychromonas ingrahamii 37]. * Record removed. The sequence YP_941742 is 100% ...
Detailed Ethanolamine Oleate dosage information for adults. Includes dosages for Esophageal Varices; plus renal, liver and ... Ethanolamine oleate has no effect upon portal hypertension, the cause of esophageal varices. Recanalization and ...
Ethanolamine Oleate (UNII: U4RY8MRX7C) (MONOETHANOLAMINE - UNII:5KV86114PT) Ethanolamine Oleate. 50 mg in 1 mL. ... ETHAMOLIN® (Ethanolamine Oleate) Injection is a mild sclerosing agent. Chemically it is C17H33COOH•NH2CH2CH2OH. It has the ... ETHAMOLIN- ethanolamine oleate injection, solution. To receive this label RSS feed. Copy the URL below and paste it into your ... ETHAMOLIN® (Ethanolamine Oleate) Injection, 5% is available in 2 mL, sterile, single-use glass ampules supplied as boxes of 10 ...
The inducer is an ethanolamine derivative. Ethanolamine is a building block for plant membrane phospholipids and signaling ... systems to a growing understanding of ethanolamine chemistry and responses of bacterial cells to ethanolamine and ethanolamine ... A plant-responsive bacterial-signaling system senses an ethanolamine derivative. Bruna G. Coutinho, Emily Mevers, Amy L. ... A plant-responsive bacterial-signaling system senses an ethanolamine derivative. Bruna G. Coutinho, Emily Mevers, Amy L. ...
Dangers of Ethanolamine Oleate Injection Treatment for Varicose Veins Br Med J 1953; 2 :726 ... Dangers of Ethanolamine Oleate Injection Treatment for Varicose Veins. Br Med J 1953; 2 doi: https://doi.org/10.1136/bmj.2.4838 ...
Here we show that niclosamide ethanolamine salt (NEN) uncouples mammalian mitochondria at upper nanomolar concentrations. Oral ... Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice. *Hanlin Tao1. , ... Hecht, G. & Gloxhuber, C. Tolerance to 2′,5-dichloro-4-nitrosalicylanilide ethanolamine salt. Z. Tropenmed. Parasitol. 13, 1-8 ... Tao, H., Zhang, Y., Zeng, X. et al. Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms ...
Ethanolamine acetate. S20U1L1S25. 54300-24-2. VVLAIYIMMFWRFW-UHFFFAOYSA-N. Ethanolamine hydrochloride. KKP3YYL02F. 2002-24-6. ... primary alcohol, primary amine, ethanolamines (CHEBI:16000) / Biogenic amines (C00189) / a small molecule (ETHANOL-AMINE) ... Ethanolamine. PDB Entries. 1aii / 1al4 / 1alx / 1alz / 1av2 / 1bdw / 1byz / 1c4d / 1gmk / 1grm … ... Ethanolamine. Accession Number. DB03994 (EXPT01366) Type. Small Molecule. Groups. Experimental. Description. A viscous, ...
Loss of Ethanolamine Utilization in Enterococcus faecalis Increases Gastrointestinal Tract Colonization Some bacteria that are ... Previously, ethanolamine, found in high concentrations in the GI tract, was shown to promote the colonization and growth of ... Ethanolamine has been linked to pathogenesis of diverse pathogens by serving as a noncompetitive metabolite that enhances ... Ethanolamine Influences Human Commensal Escherichia coli Growth, Gene Expression, and Competition with Enterohemorrhagic E. ...
Ethanolamine-13C2 for your research needs. Find product specific information including CAS, MSDS, protocols and references. ... Ethanolamine-13C2 99 atom % 13C Synonym: 2-Aminoethanol-13C2 ...
The Ethanolamines report provides pricing assessments in Asia and Europe. This trustworthy and reliable information is ... Ethanolamines news and market information products from ICIS. We offer the following regional Ethanolamines analysis and news ... About Ethanolamines. There are three main ethanolamines: monoethanolamine (MEA), diethanolamine (DEA) and triethanolamine (TEA ... Ethanolamines Methodology. Ethanolamines including monoethanolamine (MEA), diethanolamine (DEA) and triethanolamine 99% (TEA) ...
This page contains information on the chemical Ethanolamine including: 56 synonyms/identifiers; U.S. Code of Federal ... ethanol-amine*Ethanolamine*Ethanolamine solution*Ethanolamine solutions*Ethanolamine, solutions*Ethylolamine*Glycinol*Glycinol ... Ethanolamine or Ethanolamine solutions. 8. UN2491. III. 8. IB3, T4, TP1. 154. 203. 241. Forbid. Forbid. A. 52. Monoethanolamine ... beta-Aminoethyl alcohol beta-Ethanolamine*beta-ethanolamine*beta-Hydroxyethylamine*colamine*Etanolamina*Etanolamina (ITALIAN) * ...
Figure 5: Ophiobolin A (OPA) and its cytotoxic adduct with PE (OPA-PE). PE is abundant in the inner leaflet of most cell membranes. However, by unknown mechanisms, some cancer cells flip PE from the inner leaflet to the outer leaflet. OPA has been proposed to react with the PE in the outer leaflet generating a cytotoxic species that causes leaky membranes and that eventually kills the cells ...
Basis for revised IDLH: The revised IDLH for ethanolamine is 30 ppm based on acute inhalation toxicity data in animals [Treon ... 1. AIHA [1968]. Ethanolamines. In: Hygienic guide series. Am Ind Hyg Assoc J 29:312-315. ... Other animal data: Cats exposed for 2 hours to vapors of ethanolamine at concentrations reaching 970 ppm displayed vomiting ... 8. UCC [1970]. Ethanolamines. New York, NY: Union Carbide Corporation, Chemicals and Plastics, p. 30. ...
The ethanolamine degradation is enabled by the enzyme ethanolamine-ammonia lyase (EC 4.3.1.7), which cleaves ethanolamine to ... The regulation of ethanolamine lyase is most extensively studied for S. Typhimurium, where cobalamin and ethanolamine are both ... Ethanolamine-ammonia lyase, the enzyme that breaks ethanolamine into acetaldehyde and ammonia, is encoded by the gene tandem ... On the other hand, the core component of the ethanolamine utilization reaction, the EutBC enzyme, as well as ethanolamine ...
Ethanolamine utilization has been best studied in S. typhimurium (11). The catabolism of ethanolamine occurs in a multiprotein ... Ethanolamine catabolism mediated by coenzyme B12-dependent ethanolamine ammonia-lyase in Escherichia coli and Klebsiella ... and enterococci can catabolize various energy sources including ethanolamine (2). Ethanolamine is a product of the catabolism ... Indeed, growth on ethanolamine as the sole carbon source in E. faecalis requires AdoCbl (10). Sensitivity of the EutWV 2- ...
The substance decomposes on heating and on burning producing toxic and corrosive gases including nitrogen oxides. The substance is a medium strong base. Reacts with cellulose nitrate causing fire and explosion hazard. Reacts violently with strong acids and strong oxidants. Attacks copper, aluminium and their alloys, and rubber ...
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
Choline/ethanolamine kinase (CHKB), Ethanolamine kinase 2 (ETNK2), Ethanolamine kinase 1 (ETNK1), Choline kinase alpha (CHKA) ... Choline/ethanolamine kinase. Alternative name(s):. Choline kinase beta (EC:2.7.1.32*Search proteins in UniProtKB for this EC ... Choline/ethanolamine kinaseAdd BLAST. 394. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ... ethanolamine kinase activity Source: UniProtKBInferred from direct assayi*. Ref.9 ...
Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not ... Ethanolamine kinase 2 (Etnk2), Choline/ethanolamine kinase (Chkb), Ethanolamine kinase 1 (Etnk1), Choline kinase alpha (Chka) ... Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not ... Choline/ethanolamine kinase. Alternative name(s):. Choline kinase beta (EC:2.7.1.32*Search proteins in UniProtKB for this EC ...
Buy Ciclopirox ethanolamine (Ciclopirox olamine), Na+ K+ ATPase substrate (CAS 41621-49-2), a broad spectrum antifungal agent; ...
Ethanolamine (2-aminoethanol) molecule. Stylized skeletal formula (chemical structure). Atoms are shown as color-coded circles ... Caption: Ethanolamine (2-aminoethanol) molecule. Stylized skeletal formula (chemical structure). Atoms are shown as color-coded ... ethanolamine, flat, flue, formula, gas, glycinol, icon, line, mea, model, molecular, molecule, monoethanolamine, odor, ...
  • In enzymology, an ethanolamine kinase (EC 2.7.1.82) is an enzyme that catalyzes the chemical reaction ATP + ethanolamine ⇌ {\displaystyle \rightleftharpoons } ADP + O-phosphoethanolamine Thus, the two substrates of this enzyme are ATP and ethanolamine, whereas its two products are ADP and O-phosphoethanolamine. (wikipedia.org)
  • Other names in common use include ethanolamine kinase (phosphorylating), and ethanolamine phosphokinase. (wikipedia.org)
  • Regulation involves specific sensing of ethanolamine by a sensor histidine kinase (EutW), resulting in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing a RNA-binding domain. (pnas.org)
  • There are no publications for ethanolamine kinase RNAi (H00055500-R02). (novusbio.com)
  • Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. (nih.gov)
  • Ethanolamine is a building block for plant membrane phospholipids and signaling molecules. (pnas.org)
  • Ethanolamine is the second-most-abundant head group substances for phospholipids. (sbwire.com)
  • In contrast, NMDA strongly reduced the incorporation of [ 3 H]choline and [ 3 H]ethanolamine into their respective phospholipids. (jneurosci.org)
  • The presence of relatively high concentrations of plasmalogen choline and ethanolamine in the heart of many animal species suggests a role of these ether-linked phospholipids in the pathophysiology of certain myocardial diseases. (biomedsearch.com)
  • Use of radioactive ethanolamine incorporation into phospholipids to assess in vitro antimalarial activity by the semiautomated microdilution technique. (asm.org)
  • When culture parameters were carefully controlled, [3H]ethanolamine incorporation into phospholipids was proportional to pulse time, precursor concentration, and initial parasitemia and was sensitive to the number of uninfected erythrocytes (hematocrit). (asm.org)
  • Abstract- Choline and ethanolamine phospholipids in the 105,000 g supernatant fraction of rat brain exhibited density and electrophoretic properties consistent with their binding to protein. (elsevier.com)
  • Following intracranial injection of [2‐ 3 H]glycerol, the specific radioactivities of the choline and ethanolamine phospholipids in the supernatant fraction were higher than those in the microsomal fraction at all time points examined, from 15 min to 12 h after injection. (elsevier.com)
  • The properties of cytoplasmic lipoproteins containing choline and ethanolamine phospholipids have been compared with those which we have previously described containing sulphatide. (elsevier.com)
  • Benjamins, JA & McKhann, GM 1973, ' PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN ', Journal of Neurochemistry , vol. 20, no. 4, pp. 1121-1129. (elsevier.com)
  • McKhann, G. M. / PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN . (elsevier.com)
  • Ethanolamine-ammonia lyase, the enzyme that breaks ethanolamine into acetaldehyde and ammonia, is encoded by the gene tandem eutBC . (asm.org)
  • Ethanolamine lyase produces acetaldehyde, which is converted by the oxidoreductase EutE to acetyl-coenzyme A, which enters the carbon pool of the cell. (asm.org)
  • Two genes ( eutBC ) encode subunits of the cobalamin-dependent ethanolamine ammonia lyase ( 27 , 45 ), which converts ethanolamine to acetaldehyde and ammonia ( 13 , 50 ). (asm.org)
  • Ethanolamine ammonia-lyase (EAL) (EC 4.3.1.7) or ethanolamine deaminase catalyzes the AdoCbl-dependent conversion of ethanolamine (EA) to acetaldehyde and ammonia ( 3 ) ( Equation 1 ). (pubmedcentralcanada.ca)
  • Bacterial breakdown of ethanolamine, mediated by the 17-member ethanolamine utilization operon ( Fig. 1A ), results in production of ammonia and acetaldehyde. (asm.org)
  • Ethanolamine catabolism also requires the construction of bacterial microcompartments that serve to concentrate reaction intermediates and potentially limit toxic effects of acetaldehyde on the cell ( 16 ). (asm.org)
  • An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia. (yeastrc.org)
  • Previous studies have revealed the presence of eutBC genes encoding ethanolamine-ammonia lyase, a key enzyme that breaks ethanolamine into acetaldehyde and ammonia, in about 100 bacterial genomes including members of gamma-proteobacteria. (biomedcentral.com)
  • After its entry into the cytoplasm by the action of the transporter proteins EutH and/or eat [ 2 , 4 ] and possibly by passive diffusion [ 6 ], ethanolamine is broken down into ammonia and acetaldehyde by ethanolamine ammonia lyase encoded by the genes eutB and eutC . (biomedcentral.com)
  • Ethanolamine is then broken down into ammonia and acetaldehyde by the EutBC complex. (biomedcentral.com)
  • The microcompartment made up of the EutKLMNS structural proteins help sequester volatile metabolites like acetaldehyde and the enzymes required for ethanolamine utilization. (biomedcentral.com)
  • Ethanolamine ammonia lyase catalyzes the deamination of ethanolamine to form acetaldehyde and ammonia - a transformation that requires coenzyme 612- The function of coenzyme 612 is to abstract a hydrogen atom from C1 of the substrate, ethanolamine, to generate a free radical intermediate. (elsevier.com)
  • 2-5 ml of ethanolamine oleate can be injected into the mucosa just above the hemorrhoids to cause ulceration and mucosal fixation thus preventing hemorrhoids from descending out of the anal canal. (wikipedia.org)
  • Ethanolamine oleate has no effect upon portal hypertension, the cause of esophageal varices. (drugs.com)
  • ETHAMOLIN ® (Ethanolamine Oleate) Injection is a mild sclerosing agent. (nih.gov)
  • ETHAMOLIN Injection consists of ethanolamine, a basic substance, which when combined with oleic acid, forms a clear pale-yellow to straw-colored, deliquescent oleate. (nih.gov)
  • ETHAMOLIN Injection is a sterile, apyrogenic, aqueous solution containing in each mL approximately 50 mg of ethanolamine oleate with benzyl alcohol 2% by volume as preservative. (nih.gov)
  • ETHAMOLIN Injection should not be administered to subjects with a known hypersensitivity to ethanolamine, oleic acid, or ethanolamine oleate. (nih.gov)
  • To compare the clinical outcomes of balloon-occluded retrograde transvenous obliteration (BRTO) using ethanolamine oleate (EO), BRTO using sodium tetradecyl sulfate (STS) foam, and vascular plug-assisted retrograde transvenous obliteration (PARTO). (springermedizin.de)
  • The ethanolamines comprise a group of amino alcohols. (wikipedia.org)
  • In recent years, ethanolamine is not only used to be an important major material of organic chemicals but also the most valued product among amino alcohols. (techconnect.org)
  • Previously, ethanolamine, found in high concentrations in the GI tract, was shown to promote the colonization and growth of bacteria. (asm.org)
  • Ethanolamine can be used as a source of carbon and nitrogen by phylogenetically diverse bacteria. (asm.org)
  • Many bacteria can use diols, such as 1,2-propanediol, or their substituted analogs, such as ethanolamine, as sources of carbon and energy and, in the case of ethanolamine, also as the nitrogen source ( 27 ). (asm.org)
  • Effective utilization of ethanolamine as a carbon and nitrogen source may provide a survival advantage to bacteria that inhabit the gastrointestinal tract and may influence the virulence of pathogens. (pnas.org)
  • As expected, bacteria with mutations in this gene can use ethanolamine as a source of nitrogen but not carbon [a Eut(N + C − ) phenotype]. (asm.org)
  • This enzyme is essential for the growth of many bacteria on ethanolamine in the presence of exogenous vitamin B 12 ( 5 ). (pubmedcentralcanada.ca)
  • It is the first enzyme in the ethanolamine-degradative pathway of the bacteria carrying the ethanolamine utilization ( eut ) operon ( 6 ). (pubmedcentralcanada.ca)
  • Ethanolamine is an abundant molecule within mammalian hosts that plays an important role in mammalian physiology and also serves as a carbon and nitrogen source for bacteria. (prolekare.cz)
  • Ethanolamine can serve as a carbon and/or nitrogen source for bacteria in the intestine as well as within epithelial cells [ 16 , 17 ]. (prolekare.cz)
  • Although ethanolamine has profound signaling activity within mammalian cells by modulating inflammatory responses and intestinal physiology, ethanolamine is best appreciated as a nutrient for bacteria that supports growth. (microbialcell.com)
  • Gram-negative and Gram-positive bacteria encode the ethanolamine utilization ( eut ) operon. (microbialcell.com)
  • Ethanolamine exists in all living species, ranging from bacteria to humans. (ymdb.ca)
  • Ethanolamine is used as an energy source by phylogenetically diverse bacteria including pathogens, by the concerted action of proteins from the eut -operon. (biomedcentral.com)
  • Ethanolamine (2-aminoethanol, monoethanolamine, ETA, or MEA) is an organic chemical compound with the formula HOCH2CH2NH2 (C2H7NO). (wikipedia.org)
  • Ethanolamine is commonly called monoethanolamine or MEA in order to be distinguished from diethanolamine (DEA) and triethanolamine (TEA). (wikipedia.org)
  • New York, NY -- ( SBWIRE ) -- 01/18/2016 -- Ethanolamine, also known as 2-aminoethanol or monoethanolamine is an organic chemical compound which is both primary amine (organic compounds in the functional groups that has a basic nitrogen atom with a lone pair) and primary alcohol (alcohol having hydroxyl group connected to carbon atom). (sbwire.com)
  • On the bases of organic compound in the ethanolamine, global ethanolamine market can be bifurcated into monoethanolamine (MEA), diethanolamine (DEA) and triethanolamine (TEA). (sbwire.com)
  • Ethanolamine, a product of the breakdown of phosphatidylethanolamine from cell membranes, is abundant in the human intestinal tract and in processed foods. (pnas.org)
  • Ethanolamine is a product of the catabolism of phosphatidylethanolamine, an abundant phospholipid in both mammalian and bacterial membranes ( 3 , 4 ). (pnas.org)
  • Ethanolamine is abundant in cell membranes, as a component of phosphatidylethanolamine as well as in modified lipid molecules such as N -acylethanolamines [ 2 ]. (prolekare.cz)
  • Ethanolamine is abundant in the intestinal tract due to the turnover and exfoliation of enterocytes and bacterial cells [ 5 , 6 ], and intracellular pools of ethanolamine are maintained by low and high affinity uptake systems as well as through internal recycling of phosphatidylethanolamine [ 7 - 10 ]. (prolekare.cz)
  • Ethanolamine is a component of phosphatidylethanolamine, an essential phospholipid found in both mammalian and bacterial cell membranes. (asm.org)
  • The aim of this work was to determine whether S . Typhimurium relies on ethanolamine as a signal to coordinate gene expression and augment virulence in vivo . (prolekare.cz)
  • Under conditions of inflammation, Salmonella enterica serovar Typhimurium relies on ethanolamine as a supplementary carbon source used to outcompete intestinal microbiota ( 17 ). (asm.org)
  • (C) Within macrophages, Salmonella relies on ethanolamine signaling through EutR, in conjunction with SCV-containing signals, to induce robust expression of SPI-2. (microbialcell.com)
  • In this work, we describe a unique series of posttranscriptional regulatory strategies that influence expression of ethanolamine utilization genes ( eut ) in Enterococcus , Clostridium , and Listeria species. (pnas.org)
  • We report here that UPEC upregulates the expression of ethanolamine utilization genes during uncomplicated UTIs in humans. (asm.org)
  • Ethanolamine, also known as aminoethanol or glycinol, belongs to the class of organic compounds known as 1,2-aminoalcohols. (ymdb.ca)
  • Despite extensive studies of ethanolamine utilization in Salmonella enterica serovar Typhimurium, much remains to be learned about EutBC structure and catalytic mechanism, about the evolutionary origin of ethanolamine utilization, and about regulatory links between the metabolism of ethanolamine itself and the ethanolamine-ammonia lyase cofactor adenosylcobalamin. (asm.org)
  • The ethanolamine degradation is enabled by the enzyme ethanolamine-ammonia lyase (EC 4.3.1.7), which cleaves ethanolamine to ethanol and ammonia ( 8 ) and is typically encoded by two genes, which are named eutB and eutC in Salmonella enterica serovar Typhimurium. (asm.org)
  • In S. Typhimurium, all these genes are part of the eut operon ( 15 ), along with the transcriptional regulator ( eutR ) and the genes that encode the structural components of metabolosome, a bacterial microcompartment thought to play a role in preventing the escape of gaseous aldehyde but not strictly required for ethanolamine cleavage ( 7 ). (asm.org)
  • Ethanolamine utilization has been best studied in S. typhimurium ( 11 ). (pnas.org)
  • The eut operon of Salmonella typhimurium encodes proteins involved in the cobalamin-dependent degradation of ethanolamine. (asm.org)
  • Under aerobic conditions, Salmonella typhimurium can use ethanolamine as a sole source of carbon, nitrogen, and energy ( 44 , 47 ). (asm.org)
  • PLoS Pathog (2015), 11: e1005278), we demonstrated that Salmonella enterica serovar Typhimurium ( Salmonella ) exploits ethanolamine signaling to adapt to distinct host environments to precisely coordinate expression of genes encoding metabolism and virulence, which ultimately enhances disease progression. (microbialcell.com)
  • Expression of these genes in Salmonella is positively regulated by a DNA-binding transcription factor, EutR, encoded within the eut operon and active in the presence of AdoCbl and ethanolamine ( 5 , 14 ). (pnas.org)
  • one ( eutR ), encodes a positive regulator which mediates induction of the operon by vitamin B 12 plus ethanolamine. (asm.org)
  • The presence of these homologues in the eut operon of Salmonella suggests that CO 2 fixation may be a feature of ethanolamine catabolism in Salmonella . (asm.org)
  • The initial genetic analysis of the eut operon was done with mutants defective in aerobic degradation of ethanolamine on medium including cobalamin. (asm.org)
  • One previously identified gene, eutR , encodes a positive regulatory protein which mediates induction of the operon by ethanolamine plus cobalamin ( 46 , 53 ). (asm.org)
  • The eut operon encodes the components of the carboxysome-like ethanolamine utilization microcompartment, a proteinaceous organelle containing the proteins required for ethanolamine degradation ( 7 , 8 ). (pubmedcentralcanada.ca)
  • Genes encoding for ethanolamine metabolism are clustered in the eut operon [ 18 ] ( Fig 1A ). (prolekare.cz)
  • In the presence of ethanolamine and vitamin B 12 , EutR activates transcription of this operon [ 19 , 20 ]. (prolekare.cz)
  • The ethanolamine utilization operon contributes to bacterial survival via two different mechanisms. (asm.org)
  • This operon has been most widely studied in the Enterobacteriaceae , and several research groups established that this operon contains 17 genes encoding enzymes and a microcompartment necessary for the breakdown of ethanolamine (Figure 1A). (microbialcell.com)
  • Genetic studies by Roof and Roth showed that EutR is constitutively expressed at low levels from the P2 promoter, and in the presence of ethanolamine and the cofactor vitamin B 12 , EutR induces expression of the entire eut operon. (microbialcell.com)
  • In macrophages, ethanolamine metabolism does not provide a growth advantage, and expression of the eut operon is not induced. (microbialcell.com)
  • Correspondingly, several bacterial species found within the GI tract encode the machinery necessary for ethanolamine catabolism, including, but not limited to, E. faecalis , Streptococcus sanguinis , Escherichia coli , and Salmonella , Listeria , and Clostridium species. (pnas.org)
  • Under anaerobic conditions, vitamin B 12 is made, but Salmonella cannot use ethanolamine as a carbon or energy source, even with the alternative electron acceptor nitrate or fumarate. (asm.org)
  • Recently this paradox has been resolved by the finding that the anaerobic electron acceptor tetrathionate allows Salmonella to use endogenous B 12 to support anaerobic degradation of ethanolamine as a sole source of nitrogen, carbon, and energy ( 12 ). (asm.org)
  • Anaerobic use of ethanolamine may be important to Salmonella , since this carbon source is a constituent of an abundant class of lipids which would be provided to anaerobic gut inhabitants as part of the host's dietary intake. (asm.org)
  • Here we show that the foodborne pathogen Salmonella enterica exploits ethanolamine as a signal of distinct host environments to coordinate metabolism and virulence, which enhances disease progression during infection. (prolekare.cz)
  • Ethanolamine metabolism has been implicated as an important pathway for pathogenesis of such intestinal colonizers as enterohemorrhagic E. coli (EHEC), Listeria , and Salmonella ( 9 - 15 ). (asm.org)
  • Salmonella senses ethanolamine through EutR to recognize the changing host environment and direct metabolism and then virulence. (microbialcell.com)
  • To address this, we investigated ethanolamine signaling in Salmonella pathogenesis. (microbialcell.com)
  • In recent past, a great deal of information on the process of utilization of ethanolamine has been obtained by studying Salmonella enterica as a model organism. (biomedcentral.com)
  • This discovery connects at least one of the plant-responsive LuxR homolog systems to a growing understanding of ethanolamine chemistry and responses of bacterial cells to ethanolamine and ethanolamine derivatives. (pnas.org)
  • Synthesis and anti-inflammatory effects of new piperazine and ethanolamine derivatives of H(1)-antihistaminic drugs. (sigmaaldrich.com)
  • In this paper, Cyclizine (1-benzhydryl-4-methyl-piperazine, I), bromodiphenhydramine (2-[(4-bromophenyl)-phenylmethoxy]-N, N-dimethylethanamine, II) and some of their new piperazine and ethanolamine derivatives (III-VIII) inducing changes in substitution of phenyl and amine moieties were synthesized and their acute and chronic antiinflammatory effects were evaluated by standard pharmacological tests. (sigmaaldrich.com)
  • The other series of tracers is 11C labeled ethanolamine amine derivatives, which targets the altered lipid metabolism associated with increased cellular proliferation in tumors. (upenn.edu)
  • Here, we developed 11C labeled ethanolamine and two ethanolamine derivatives - N-methyl ethanolamine and N,N-dimethyl ethanolamine. (upenn.edu)
  • We successfully synthesized LEA and LEA-d4 as well as their 15-lipoxygenase-derived derivatives, namely 13-hydroxy-9Z,11E-octadecadienoyl-N-ethanolamine (13-HODE-EA) and 13-HODE-EA-d4, using Novozyme 435 immobilized on acrylic resin and soybean lipoxygenase respectively. (indigobiosciences.com)
  • Ethylene oxide is used as a chemical intermediate for the synthesis of a wide variety of EO derivatives such as Surfactants, Ethanolamines and Glycolethers. (ineos.com)
  • Ethanolamines are one of the most versatile members of the EO derivatives family. (ineos.com)
  • This fusion was followed by recruitment and occasional loss of auxiliary ethanolamine utilization genes in Firmicutes and by several horizontal transfers, most notably from the firmicute stem to the Enterobacteriaceae and from Alphaproteobacteria to Actinobacteria . (asm.org)
  • Finally, we found that the food poisoning phenotype is associated with the structural components of metabolosome more strongly than with ethanolamine utilization genes or with paralogous propanediol utilization genes per se. (asm.org)
  • Together, these results suggest an intricate and carefully coordinated interplay of multiple regulatory strategies for control of ethanolamine utilization genes. (pnas.org)
  • For Listeria monocytogenes , the genes of the ethanolamine utilization ( eut ) locus exhibit increased expression inside the host cell, and loss of one of the key enzymes, EutB, causes a defect in intracellular growth ( 6 ). (pnas.org)
  • Inhibitors of the pathway are of interest because considerable numbers of pathogens that carry the ethanolamine utilization genes are causative agents of food poisoning ( 9 ). (pubmedcentralcanada.ca)
  • Additionally, we reported that enterohemorrhagic Escherichia coli exploits ethanolamine signaling through EutR to activate expression of virulence genes in vitro, which established the importance of ethanolamine as a bacterial signaling molecule. (microbialcell.com)
  • Our comparative genomics study reveals the presence of genes that are involved in ethanolamine utilization in several Vibrio species. (biomedcentral.com)
  • Choline and ethanolamine glycerophospholipids are amphipathic molecules that are asymmetrically distributed in the bilayer. (springer.com)
  • Choline and ethanolamine glycerophospholipids are synthesized at the endoplasmic reticulum and are transported to other membranous structures by phospholipid exchange and transfer proteins. (springer.com)
  • Fatty acid profiles of plasmalogen choline and ethanolamine glycerophospholipids in pig and rat hearts. (biomedsearch.com)
  • This study examined the fatty acid composition of the choline and ethanolamine glycerophospholipids in pig heart and compared the results with those in rat heart. (biomedsearch.com)
  • a phospholipid containing ethanolamine that is a major constituent of cell membranes and is localized preferentially in the inner surface of the plasma membrane. (thefreedictionary.com)
  • Altogether, our findings suggest that ethanolamine, an intrinsic component of bacterial and mammalian cell membranes, functions as a signal to modulate metabolism and virulence and suggest a new layer of complexity in chemical signaling that underlies pathogenicity. (prolekare.cz)
  • however, ethanolamine failed to bind to the periplasmic-binding protein (PBP) required for the signal response. (pnas.org)
  • Subcellular fractionation showed this protein to distribute similarly to a 46-kDa [ 3 H]ethanolamine-labeled protein reported previously (Tisdale, E.J., and Tartakoff, A.M. (1988) J. Biol. (elsevier.com)
  • In particular, the protein was enriched in cytosolic and microsomal fractions relative to plasma membrane and thus did not appear to correspond to the class of proteins with glycoinositol phospholipid anchors, the only post-translational protein modification involving ethanolamine that had been described previously. (elsevier.com)
  • Copurification of rabbit EF-1α and the [ 3 H]ethanolamine-labeled protein from K562 cells further supported this identification. (elsevier.com)
  • Amino acid analysis demonstrated 1 residue of ethanolamine in each peptide, and peptide sequencing revealed that the ethanolamine-containing component(s) was attached to Glu 301 and Glu 374 in the EF-1α protein sequence deduced from a human EF-1α cDNA. (elsevier.com)
  • These data confirm a new class of post-translational protein modifications involving ethanolamine. (elsevier.com)
  • The catabolism of ethanolamine occurs in a multiprotein complex called the carboxysome, and results in the production of the metabolically useful compound acetyl-CoA ( 12 ). (pnas.org)
  • Ethanolamine-ammonia lyase requires adenosylcobalamin ( 28 ), which in different species may be imported from the environment, produced de novo, or synthesized from precursors, such as cyanocobalamin or hydroxycobalamin. (asm.org)
  • The excess of these precursors inhibits ethanolamine-ammonia lyase, and the reactivating factor EutA is used in several species to prevent EutBC inhibition. (asm.org)
  • The activities of the enzymes ethanolamine ammonia-lyase, CoA-dependent and CoA-independent aldehyde dehydrogenases, and isocitrate lyase were assayed in Escherichia coli which had been grown on various sources of carbon and nitrogen. (nih.gov)
  • Induction of ethanolamine ammonia-lyase and of maximal levels of both aldehyde dehydrogenases required the concerted effects of ethanolamine and vitamin (or coenzyme) B12. (nih.gov)
  • No evidence was found for structural relationships between ethanolamine ammonia-lyase, CoA-dependent aldehyde dehydrogenase and CoA-independent aldehyde dehydrogenase, but mutant and physiological studies demonstrated that the induction of the first two enzymes is under common control. (nih.gov)
  • The Global Ethanolamine market is considered at XX million USD in 2016 and is exacted to reach XX million USD by the end of 2022, rising at a CAGR of XX% between 2016 and 2022. (eontarionow.com)
  • Ethanolamine is a colorless, viscous liquid with an odor reminiscent of ammonia. (wikipedia.org)
  • Ethanolamine is a corrosive, colorless, flammable, viscous and toxic liquids substance which is used in solutions and dispersions to scrub acids, feedstock material in the manufacture of detergents, emulsification agents, varnishes & polishes and other chemical intermediaries. (sbwire.com)
  • Ethanolamines are corrosive, colorless, flammable, and viscous liquids that are produced by the reaction of ethylene oxide and ammonia. (marketresearch.com)
  • Ethanolamines are clear, colorless, viscous liquids with ammonia-like odors, which have the combined properties of alcohols and amines. (annmariegianni.com)
  • Specifically, scientists at Human Metabolome Technologies (HMT) and Japan's Keio University presented data earlier this week at a scientific conference in Tokyo, showing that they could diagnose depression by measuring levels of a chemical-ethanolamine phosphate-in patients' blood. (thoughtbroadcast.com)
  • That's right: next time you see your primary doc, he or she might order-along with your routine CBC and lipid panel-an ethanolamine phosphate test. (thoughtbroadcast.com)
  • Further, what the heck is ethanolamine phosphate, and why would it be low in depressed people? (thoughtbroadcast.com)
  • other major application of ethanolamine are in the field of construction chemicals, corrosion inhibitors for metal protection. (sbwire.com)
  • Additionally, increasing demand from the developing markets such as India and China paired with invention of new application in the field of wood preservation, construction chemicals corrosion inhibitors for metal protection is further expected to increase the global demand for ethanolamine substance. (sbwire.com)
  • Ethanolamines are used as corrosion inhibitors because they are an effective scavenger for sulfur containing gases. (mfa.org)
  • The global ethanolamines market is expected to witness a CAGR of approximately 4.4% during the forecast period, majorly driven by the rising demand from corrosion inhibitors and glysophate herbicides applications. (marketresearch.com)
  • The demand for ethanolamines from corrosion inhibitors for metal protection, and glysophate herbicides are expected to drive the market extensively during the forecast period. (marketresearch.com)
  • We used computational analysis of sequences, structures, genome contexts, and phylogenies of ethanolamine-ammonia lyases to address these questions and to evaluate recent data-mining studies that have suggested an association between bacterial food poisoning and the diol utilization pathways. (asm.org)
  • Both the host diet and cells within the intestine (bacterial and epithelial) are thought to provide a rich ethanolamine source ( 5 ). (pnas.org)
  • thus, these studies reveal that ethanolamine signaling may be important for bacterial adaptation to the mammalian host. (prolekare.cz)
  • Ethanolamine is abundant in the gastrointestinal (GI) tract from dietary sources as well as from the normal turnover of intestinal epithelial and bacterial cells in the gut. (microbialcell.com)
  • However, the question remained whether ethanolamine signaling influences bacterial virulence in vivo . (microbialcell.com)
  • The systematic name of this enzyme class is ATP:ethanolamine O-phosphotransferase. (wikipedia.org)
  • PCYT2 is an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. (creativebiomart.net)
  • In this study we identify a chemical derived from ethanolamine that induces PipR activity at picomolar concentrations, and we present evidence that this is the active inducer present in plant leaf macerates. (pnas.org)
  • Here we show that niclosamide ethanolamine salt (NEN) uncouples mammalian mitochondria at upper nanomolar concentrations. (nature.com)
  • On the same test, ethanolamine-O-sulphate, which raises brain gamma-aminobutyric acid, was without effect, suggesting raised concentrations of this acid are not essential for anxiety reduction. (biomedsearch.com)
  • Transparency Market Research indicates that while the growing usage of ethanolamines in a wide range of applications is estimated to give the global market the boost it requires, the volatility in raw material prices is predicted to restrict the market growth at a 4.1% CAGR from 2016 to 2024. (openpr.com)
  • The U.S. and China are the largest consumer of ethanolamine substance globally and are expected to lead the market in the coming future. (sbwire.com)
  • Now, China is the second largest producer and consumer of ethanolamine in the world, only next to the US. (1888pressrelease.com)
  • In 2015, Asia Pacific and North America accounted for a share of approximately 70% in the ethanolamines market, boosted by the increasing demand for ethanolamines in surfactants and herbicides applications. (openpr.com)
  • The rising production of herbicides in China is also predicted to considerably propel the demand for ethanolamines in the next few years. (openpr.com)
  • A number of countries in Southeast Asia and ASEAN are projected to record promising growth during the forecast period due to the surging demand for ethanolamines in major application segments. (openpr.com)
  • A steady growth in the production of glyphosate-based herbicides has significantly driven the demand for ethanolamines in North America in 2015. (openpr.com)
  • Demand for ethanolamines in Asia was mostly lacklustre in Q1 2019, despite feedstock spikes. (icis.com)
  • Additionally, the rising investments in the construction sector from both the government and international companies (owing to growing tourism and business opportunities) in these economies are expected to boost the demand for ethanolamines from the cement grinding segment. (marketresearch.com)
  • The results suggest that ethanolamine interacts more strongly with anions than choline does. (sciencemag.org)
  • Breakdown of ethanolamine requires adenosylcobalamin (AdoCbl) as a cofactor, and, intriguingly, we also identify an intercistronic AdoCbl riboswitch that has a predicted structure different from previously established AdoCbl riboswitches. (pnas.org)
  • Metabolic labeling experiments in whole cells showed that NMDA receptor overactivation does not modify the activity of phosphocholine or phosphoethanolamine cytidylyltransferases but strongly inhibits choline-ethanolamine phosphotransferase activity. (jneurosci.org)
  • In 2015, surfactants emerged as the leading application segment of the ethanolamines market. (openpr.com)
  • Surfactants produced from ethanolamines are used in heavy-duty laundry detergents, industrial cleaners, cosmetics, and other foam-based personal care products. (openpr.com)
  • In 2012, more than one third of ethanolamines were used in the manufacturing of surfactants. (sbwire.com)
  • Majority of ethanolamine compound is used in the manufacturing of surfactants, which is expected to dominate the global market in the forecasted period. (sbwire.com)
  • The soaps of ethanolamines are used in shampoos, as surfactants and as emulsifiers . (mfa.org)
  • Application Notes: Ethanolamines are commonly used basic compounds which often act as surfactants and cleansing agents. (sielc.com)
  • N-Arachidonoyl-ethanolamine (AEA) is an endocannabinoid (eCB) and endogenous lipid mimicking many of the effects of Δ9-tetrahydrocannabinol, notably on brain functions, appetite, pain and inflammation. (indigobiosciences.com)
  • Ethanolamine acts as a weak base compound (chemical base that does not ionize fully in an aqueous solution). (sbwire.com)
  • BASF and Dow Chemical Corporation lead the global manufacturing of ethanolamine. (sbwire.com)
  • See pricing info, deals and product reviews for HCL Ethanolamine GHS Chemical Label, 3' x 5', Adhesive Vinyl, White/Red, 25 Pack (GH404900035) at Quill.com. (quill.com)
  • Chemical and Solvent Resistant OSHA-GHS Compliant Label is designed for easy Secondary Chemical Container Application Protect the workforce and remain compliant with this Ethanolamine Secondary Container GHS Label. (quill.com)
  • Ethanolamine GHS Label will save you time and effort when organizing your chemical library. (quill.com)
  • Ethanolamine chemical safety label complies with the OSHA HazCom standard 1910.1200, which is now aligned with the Globally Harmonized System (GHS) for Identifying and Labeling hazardous chemicals. (quill.com)
  • The Material Safety Data Sheet for ethanolamine notes that skin contact may be harmful, and that the material can produce chemical burns and may cause inflammation. (annmariegianni.com)
  • The standard reactions in ethanolamine utilization are diagrammed in Fig. 1 , with proposed roles for several Eut proteins. (asm.org)
  • Biosynthetic incorporation of [ 3 H]ethanolamine into proteins was assessed in the human erythroleukemia cell line K562. (elsevier.com)
  • Apart from these enzymes, other proteins contribute indirectly in the ethanolamine utilization process. (biomedcentral.com)
  • Ethanolamine is transported into the cytoplasm by the action of transporter proteins EutH, eat and via passive diffusion. (biomedcentral.com)
  • Evidence is presented for the operation of a previously unreported pathway of ethanolamine metabolism in E. coli. (nih.gov)
  • Suggested pathway for metabolism of ethanolamine. (asm.org)
  • We demonstrate that although ethanolamine metabolism mutants do not show increased susceptibility to antimicrobial responses of neutrophils, this metabolic pathway is important for surviving the innate immune system during UTI. (asm.org)
  • Phosphorylates ethanolamine, and can also act on choline (in vitro). (uniprot.org)
  • The use of [3H]ethanolamine for in vitro antimalarial drug screening is a good alternative to the method of Desjardins et al. (asm.org)
  • Using Vibrio alginolyticus as a model system we demonstrate that ethanolamine is better utilized as a nitrogen source than as a carbon source. (biomedcentral.com)
  • A member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol. (ebi.ac.uk)
  • We identified a conserved DNA motif that likely represents the EutR-binding site and is shared by the ethanolamine and cobalamin operons in several enterobacterial species, suggesting a mechanism for coupling the biosyntheses of apoenzyme and cofactor in these species. (asm.org)
  • Here, we show that the intramacrophage environment promotes expression of the ethanolamine utilization transcription factor EutR, which directly activates SPI-2. (prolekare.cz)
  • Previously, we used biochemical approaches and demonstrated that EutR directly senses ethanolamine and binds to the eutS (P1) promoter to activate transcription (Figure 1A). (microbialcell.com)
  • Ethanolamine has been linked to pathogenesis of diverse pathogens by serving as a noncompetitive metabolite that enhances pathogen growth as well as a signal that modulates virulence. (asm.org)
  • These data suggest that the ability to use ethanolamine may affect virulence. (pnas.org)
  • The global market for ethanolamines has been geographically segmented into North America, Latin America, Asia Pacific, Europe, and the Middle East and Africa. (openpr.com)
  • The presence of major herbicide manufacturers in the U.S. has enabled herbicides to be the largest application segment of the North America ethanolamines market. (openpr.com)
  • North America has the largest market share for ethanolamines substances, followed by Europe and Asia-Pacific. (sbwire.com)
  • We provide independent and unbiased information on manufacturers, prices, production news and consumers for the global and regional (North America, Asia and Europe) market of N-oleoyl ethanolamine. (reportsnreports.com)
  • These ethanolamine-containing compounds play important roles in mammalian cell signaling and influence diverse physiological effects, including cytokinesis, immunomodulation, food intake and energy balance [ 2 - 4 ]. (prolekare.cz)
  • 3H]ethanolamine is also an ideal tool when compounds that interfere with DNA and/or RNA metabolism are to be investigated for their effect on Plasmodium growth. (asm.org)
  • The eCBs and eCB-like compounds contain fatty acids, the main classes being the monoacylglycerols and the N-acyl-ethanolamines (NAEs). (indigobiosciences.com)
  • Ethanolamines are ammonia compounds used in cosmetics as emulsifiers or foaming agents. (annmariegianni.com)
  • Almost all of the compounds you have listed under Avoid are not actually ethanolamines. (annmariegianni.com)
  • In addition, EHEC, while unable to grow on ethanolamine as a sole carbon source, outcompetes microbiota of the bovine intestinal tract by using ethanolamine breakdown products as an additional source of nitrogen ( 14 ). (asm.org)
  • As far as I can tell from a quick literature search, there has been no report-or even a suggestion-of ethanolamine (or any of its metabolites) being involved in the pathogenesis of mood disorders. (thoughtbroadcast.com)