Primary Ovarian Insufficiency: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.Gonadal Dysgenesis, 46,XX: The 46,XX gonadal dysgenesis may be sporadic or familial. Familial XX gonadal dysgenesis is transmitted as an autosomal recessive trait and its locus was mapped to chromosome 2. Mutation in the gene for the FSH receptor (RECEPTORS, FSH) was detected. Sporadic XX gonadal dysgenesis is heterogeneous and has been associated with trisomy-13 and trisomy-18. These phenotypic females are characterized by a normal stature, sexual infantilism, bilateral streak gonads, amenorrhea, elevated plasma LUTEINIZING HORMONE and FSH concentration.Menopause, Premature: The premature cessation of menses (MENSTRUATION) when the last menstrual period occurs in a woman under the age of 40. It is due to the depletion of OVARIAN FOLLICLES. Premature MENOPAUSE can be caused by diseases; OVARIECTOMY; RADIATION; chemicals; and chromosomal abnormalities.Fragile X Mental Retardation Protein: A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.Ovarian Diseases: Pathological processes of the OVARY.Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)Trinucleotide Repeat Expansion: An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs.Estrogens: Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.Ovary: The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.Ovarian Follicle: An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.Galactosemias: A group of inherited enzyme deficiencies which feature elevations of GALACTOSE in the blood. This condition may be associated with deficiencies of GALACTOKINASE; UDPGLUCOSE-HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; or UDPGLUCOSE 4-EPIMERASE. The classic form is caused by UDPglucose-Hexose-1-Phosphate Uridylyltransferase deficiency, and presents in infancy with FAILURE TO THRIVE; VOMITING; and INTRACRANIAL HYPERTENSION. Affected individuals also may develop MENTAL RETARDATION; JAUNDICE; hepatosplenomegaly; ovarian failure (PRIMARY OVARIAN INSUFFICIENCY); and cataracts. (From Menkes, Textbook of Child Neurology, 5th ed, pp61-3)Amenorrhea: Absence of menstruation.Gonadal Dysgenesis, 46,XY: Defects in the SEX DETERMINATION PROCESS in 46, XY individuals that result in abnormal gonadal development and deficiencies in TESTOSTERONE and subsequently ANTIMULLERIAN HORMONE or other factors required for normal male sex development. This leads to the development of female phenotypes (male to female sex reversal), normal to tall stature, and bilateral streak or dysgenic gonads which are susceptible to GONADAL TISSUE NEOPLASMS. An XY gonadal dysgenesis is associated with structural abnormalities on the Y CHROMOSOME, a mutation in the GENE, SRY, or a mutation in other autosomal genes that are involved in sex determination.Turner Syndrome: A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Receptors, Estrogen: Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.Anatomy, Cross-Sectional: Descriptive anatomy based on three-dimensional imaging (IMAGING, THREE-DIMENSIONAL) of the body, organs, and structures using a series of computer multiplane sections, displayed by transverse, coronal, and sagittal analyses. It is essential to accurate interpretation by the radiologist of such techniques as ultrasonic diagnosis, MAGNETIC RESONANCE IMAGING, and computed tomography (TOMOGRAPHY, X-RAY COMPUTED). (From Lane & Sharfaei, Modern Sectional Anatomy, 1992, Preface)Adrenal Insufficiency: Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.Steroidogenic Factor 1: A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.Estrogen Receptor alpha: One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function differs from, and in some ways opposes, ESTROGEN RECEPTOR BETA.Infertility, Female: Diminished or absent ability of a female to achieve conception.Chromosomes, Human, X: The human female sex chromosome, being the differential sex chromosome carried by half the male gametes and all female gametes in humans.Estrogen Receptor beta: One of the ESTROGEN RECEPTORS that has greater affinity for ISOFLAVONES than ESTROGEN RECEPTOR ALPHA does. There is great sequence homology with ER alpha in the DNA-binding domain but not in the ligand binding and hinge domains.Follicle Stimulating Hormone: A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.Menstruation Disturbances: Variations of menstruation which may be indicative of disease.Obstetrics: A medical-surgical specialty concerned with management and care of women during pregnancy, parturition, and the puerperium.Estrogens, Conjugated (USP): A pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.Medroxyprogesterone Acetate: A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.Estrogen Replacement Therapy: The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.Progestins: Compounds that interact with PROGESTERONE RECEPTORS in target tissues to bring about the effects similar to those of PROGESTERONE. Primary actions of progestins, including natural and synthetic steroids, are on the UTERUS and the MAMMARY GLAND in preparation for and in maintenance of PREGNANCY.Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.Perimenopause: The transitional period before and after MENOPAUSE. Perimenopausal symptoms are associated with irregular MENSTRUAL CYCLE and widely fluctuated hormone levels. They may appear 6 years before menopause and subside 2 to 5 years after menopause.North AmericaClimacteric: Physiologic period, characterized by endocrine, somatic, and psychic changes with the termination of ovarian function in the female. It may also accompany the normal diminution of sexual activity in the male.Nephrons: The functional units of the kidney, consisting of the glomerulus and the attached tubule.Fund Raising: Usually organized community efforts to raise money to promote financial programs of institutions. The funds may include individual gifts.Oogonia: Euploid female germ cells of an early stage of OOGENESIS, derived from primordial germ cells during ovarian differentiation. Oogonia undergo MEIOSIS and give rise to haploid OOCYTESInternship and Residency: Programs of training in medicine and medical specialties offered by hospitals for graduates of medicine to meet the requirements established by accrediting authorities.Financial Support: The provision of monetary resources including money or capital and credit; obtaining or furnishing money or capital for a purchase or enterprise and the funds so obtained. (From Random House Unabridged Dictionary, 2d ed.)Financial Management: The obtaining and management of funds for institutional needs and responsibility for fiscal affairs.PhilippinesLinitis Plastica: A condition where the stomach wall becomes thickened, rubbery and loses its ability to distend. The stomach assumes a "leather bottle" shape. It is most often seen in adenocarcinoma of the stomach. The term is often used synonymously with diffuse adenocarcinoma of the stomach.Transportation: The means of moving persons, animals, goods, or materials from one place to another.Anxiety: Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.Stomach Neoplasms: Tumors or cancer of the STOMACH.Thyroid Gland: A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.Thyroid Hormones: Natural hormones secreted by the THYROID GLAND, such as THYROXINE, and their synthetic analogs.Thyroid Diseases: Pathological processes involving the THYROID GLAND.Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA.Thyroid Nodule: A small circumscribed mass in the THYROID GLAND that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (GOITER, NODULAR).Thyroid Function Tests: Blood tests used to evaluate the functioning of the thyroid gland.
Ovarian dysfunction (E28.0) Estrogen excess (E28.1) Androgen excess (E28.2) Polycystic ovarian syndrome (E28.3) Primary ovarian ... Primary adrenocortical insufficiency Addison's disease (E27.2) Addisonian crisis (E27.3) Drug-induced adrenocortical ... insufficiency (E27.4) Other and unspecified adrenocortical insufficiency Hypoaldosteronism Adrenocortical insufficiency NOS ( ... Primary hyperaldosteronism Conn's syndrome Primary aldosteronism due to adrenal hyperplasia (bilateral) (E26.1) Secondary ...
... low estrogen levels amenorrhea. They named the condition "primary ovarian insufficiency" to distinguish the condition from ... The term "primary ovarian insufficiency" was first used in 1942 by Fuller Albright who first described the condition. About 5 ... Women with primary ovarian insufficiency perceive lower social support than control women, so building a trusted community of ... Oktay K, Kim JY, Barad D, Babayev SN (2010). "Association of BRCA1 mutations with occult primary ovarian insufficiency: a ...
As breast and ovarian cancers require estrogen to grow, AIs are taken to either block the production of estrogen or block the ... Aromatase inhibitors have been shown to reverse age-related declines in testosterone, including primary hypogonadism. Extracts ... adrenal insufficiency, kidney failure, hair loss, and liver dysfunction. Patients with liver, kidney or adrenal abnormalities ... Estrogen is produced and acts locally in these tissues, but any circulating estrogen, which exerts systemic estrogenic effects ...
... which leads to estrogen production by granulosa cells) and progesterone by ovarian theca cells and luteal cells, respectively, ... All forms of CAH involve excessive or defective production of sex steroids and can prevent or impair development of primary or ... As with other forms of adrenal insufficiency, extra glucocorticoid is needed for stress coverage. XX females with lipoid CAH ... once they have begun to produce estrogen, lipid damage begins to accrue and the ability to produce estrogen, as well as ovulate ...
Endocrinopathies are classified as primary, secondary, or tertiary. Primary endocrine disease inhibits the action of downstream ... Redirected from Ovarian hormones). The endocrine system is the collection of glands of an organism that secrete hormones ... Adrenal insufficiency is significant because it is correlated with decreased ability to maintain blood pressure and blood sugar ... As the thyroid, and hormones have been implicated in signaling distant tissues to proliferate, for example, the estrogen ...
Mutations inHFM1in Recessive Primary Ovarian Insufficiency. New England Journal of Medicine. 2014, 370 (10): 972-974. ISSN 0028 ... Estrogen production and action. J. Am. Acad. Dermatol. 2001-09, 45 (3 Suppl): S116-24. PMID 11511861. doi:10.1067/mjd. ... Ovarian torsion) · 卵巢中风(英语:Ovarian apoplexy) · 经间痛(英语:Mittelschmerz) · 女性不孕症(停止排卵(英语:Anovulation),卵巢储备功能不足(英语:Poor ovarian ... 卵巢疾病(英语:Ovarian disease). 卵巢炎 · 卵巢囊肿(卵巢滤泡囊
Secretion of estrogens by the ovarian follicles begins at puberty under the influence of FSH. Estrogens stimulate maturation of ... Endocrinopathies are classified as primary, secondary, or tertiary. Primary endocrine disease inhibits the action of downstream ... Adrenal insufficiency is significant because it is correlated with decreased ability to maintain blood pressure and blood sugar ... It works with estrogens in establishing the menstrual cycle. The testes of the male begin to produce testosterone at puberty in ...
Decreased incidence of primary dysmenorrhea, ovulation pain, and functional ovarian cysts. Decreased incidence of seizures in ... In combination with estrogens in general, MPA may increase the risk of cardiovascular disease, with a stronger association when ... and adrenal insufficiency at sufficiently high doses. MPA has been found to act as a competitive inhibitor of rat 3α- ... Inhibition of ovarian function during DMPA use causes the endometrium to become thin and atrophic. These changes in the ...
Wang, Jian; Zhang, Wenxiang; Jiang, Hong; Wu, Bai-Lin (2014). "Mutations inHFM1in Recessive Primary Ovarian Insufficiency". New ... Fat cells produce estrogen, in addition to the primary sex organs. Too much body fat causes production of too much estrogen and ... Diminished ovarian reserve, also see Poor Ovarian Reserve Premature menopause Menopause Luteal dysfunction Gonadal dysgenesis ( ... Infertility can further be broken down into primary and secondary infertility. Primary infertility refers to the inability to ...
Recent research suggests that premature ovarian aging and premature ovarian failure (aka primary ovarian insufficiency) may ... "Effects of pretreatment with estrogens on ovarian stimulation with gonadotropins in women with premature ovarian failure: a ... While the primary cause of the end to menstrual cycles is the exhaustion of ovarian follicles, there is some evidence that a ... Ultrasound measurement of ovarian volume. Lass and Brinsden (1999) report that the correlation between ovarian volume and ...
... or premature ovarian insufficiency (POI), is a female reproductive disorder characterised by at least 4 months of primary or ... In all cases of successful function restoration, it took 3.5-6.5 months after reimplantation before a rise in oestrogen, a key ... Restoration of the ovarian function occurs in almost all cases of cryopreservation, but it takes a while for the ovarian ... This concept, known as burnout, leads to a depletion of the ovarian reserve and results in premature ovarian failure. Oocyte ...
... results from having too few ovarian follicles to produce enough estrogen to maintain the ovarian-pituitary- ... September 2016). "Premature ovarian insufficiency: the context of long-term effects". Journal of endocrinological investigation ... See Meiosis.) Human primary oocytes are present at an intermediate stage of meiosis, termed prophase I (see Oogenesis). ... Low-dose prescription vaginal estrogen products such as estrogen creams are generally a safe way to use estrogen topically, to ...
... results from having too few ovarian follicles to produce enough estrogen to maintain the ovarian-pituitary- ... "Premature ovarian insufficiency: Pathogenesis and management". Journal of Mid-Life Health (Review). 6 (4): 147-53. doi:10.4103/ ... Human primary oocytes are present at an intermediate stage of meiosis, termed prophase I (see Oogenesis). Expression of four ... Premature ovarian failureEdit. Premature ovarian failure (POF) is the cessation of the ovarian function before the age of 40 ...
Oktay, K; Kim, JY; Barad, D; Babayev, SN (Jan 2010). "Association of BRCA1 mutations with occult primary ovarian insufficiency ... and unopposed estrogen for women whose uterus was removed. Estrogen can cause breast cancer, but as the amount of estrogen ... although women with a BRCA mutation may be more likely to have primary ovarian insufficiency. BRCA mutation carriers may be ... The blood test has relatively poor sensitivity and specificity for ovarian cancer. In both breast and ovarian screening, areas ...
The primary goals of hormone replacement are to protect from adrenal insufficiency and to suppress the excessive adrenal ... Blocking the effects and conversions of estrogens will allow use of lower doses of glucocorticoids with less risk of ... ovarian: Polycystic ovary syndrome. *Premature ovarian failure. *testicular: enzymatic *5α-reductase deficiency ... This article needs more medical references for verification or relies too heavily on primary sources. Please review the ...
Estrogen has been found to increase the secretion of oxytocin and to increase the expression of its receptor, the oxytocin ... And its milk ejection property was described by Ott and Scott in 1910[non-primary source needed] and by Schafer and Mackenzie ... By chance, sodium ascorbate by itself was found to stimulate the production of oxytocin from ovarian tissue over a range of ... the absence of either oxytocin or its receptor in knockout mice has not been reported to produce cardiac insufficiencies. ...
"Association of BRCA1 mutations with occult primary ovarian insufficiency: a possible explanation for the link between ... response to estrogen. • cellular response to indole-3-methanol. • negative regulation of extrinsic apoptotic signaling pathway ... where EOCs are the most common type of ovarian cancer, representing approximately 90% of ovarian cancers.[64] In serous ovarian ... Level of BRCA1 expression is also relevant to ovarian cancer treatment. Patients having sporadic ovarian cancer who were ...
... disease Erondu-Cymet syndrome Estrogen insensitivity syndrome Euthyroid sick syndrome Evans syndrome Excess ovarian androgen ... syndrome Tetra-amelia syndrome Tetralogy of Fallot Teunissen-Cremers syndrome Thevenard syndrome Thoracic insufficiency ... syndrome Precordial catch syndrome Premenstrual syndrome Presumed ocular histoplasmosis syndrome Pretzel syndrome Primary ... OSLAM syndrome Osler-Weber-Rendu disease Otodental syndrome Otofacial syndrome Ovarian hyperstimulation syndrome Ovarian vein ...
Oktay K, Kim JY, Barad D, Babayev SN (January 2010). "Association of BRCA1 mutations with occult primary ovarian insufficiency ... Kawai H, Li H, Chun P, Avraham S, Avraham HK (October 2002). "Direct interaction between BRCA1 and the estrogen receptor ... where EOCs are the most common type of ovarian cancer, representing approximately 90% of ovarian cancers. In serous ovarian ... Level of BRCA1 expression is also relevant to ovarian cancer treatment. Patients having sporadic ovarian cancer who were ...
Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy. World Health Organization. ... ISBN 978-0-300-16791-7. J. Horsky; J. Presl (6 December 2012). Ovarian Function and its Disorders: Diagnosis and Therapy. ... Phyllis Carolyn Leppert; Jeffrey F. Peipert (2004). Primary Care for Women. Lippincott Williams & Wilkins. pp. 277-. ISBN 978-0 ... they must be combined with a glucocorticoid like prednisone to avoid adrenal insufficiency. A newer drug currently under ...
Function The primary function of the hormone leptin is the regulation of adipose tissue mass through central hypothalamus ... Leptin level is decreased by increases in testosterone levels and increased by increases in estrogen levels. Leptin level is ... As such, obese individuals are in an altered state, due to a metabolic insufficiency, which requires specific nutritional ... the ovarian cycle stops and females stop menstruating. Only if a female has an extremely low body fat percentage does energy ...
... identification of variants in a cohort of women with primary ovarian insufficiency". Journal of Ovarian Research. 10 (1): 51. ... De Vos M, Devroey P, Fauser BC (September 2010). "Primary ovarian insufficiency". Lancet. 376 (9744): 911-21. doi:10.1016/S0140 ... A mutation in the NOBOX gene is associated with premature ovarian failure (POF), also known as premature ovarian insufficiency ... of cases in a large primary ovarian insufficiency cohort". Human Mutation. 32 (10): 1108-13. doi:10.1002/humu.21543. PMID ...
Resistance to selective estrogen receptor modulator drugs[edit]. Selective estrogen receptor modulators (SERMs) are a commonly ... Ford CE, Clarke CM (1963). "Cytogenetic evidence of clonal proliferation in primary reticular neoplasms". Proc Can Cancer Conf ... and survival factor insufficiency, but a cancer cell learns to "evade apoptosis", leading to the accumulation of aberrant cells ... "Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma" ...
Testicular failure is treated with testosterone replacement,[8] Ovarian failure.[8]. *Absence or unresponsiveness of target ... a low dose of testosterone or estrogen for a few months may bring the first reassuring changes of normal puberty. ... Adrenal insufficiency. (Addison's, WF). *aldosterone: Hypoaldosteronism *21α CAH. *11β CAH ... aldosterone: Hyperaldosteronism/Primary aldosteronism *Conn syndrome. *Bartter syndrome. *Glucocorticoid remediable ...
Ovarian hyper-stimulation therapy to treat infertility. [8] Compression of a vein or artery by abnormality, tumor, hematoma. [8 ... Estrogen-based oral contraceptive. discontinuation reduces risk. [8][11][14] Hormone replacement therapy. discontinuation ... of final infarct size despite timely primary percutaneous coronary intervention. This is a key reason for the continued high ... Chronic venous insufficiency. *Chronic cerebrospinal venous insufficiency. *Superior vena cava syndrome. *Inferior vena cava ...
... and estrogens like estradiol, estradiol esters, ethinylestradiol, conjugated estrogens, diethylstilbestrol, and bifluranol.[2][ ... J. Horsky; J. Presl (6 December 2012). Ovarian Function and its Disorders: Diagnosis and Therapy. Springer Science & Business ... Phyllis Carolyn Leppert; Jeffrey F. Peipert (2004). Primary Care for Women. Lippincott Williams & Wilkins. pp. 277-. ISBN 978-0 ... they must be combined with a glucocorticoid like prednisone to avoid adrenal insufficiency.[107] A newer drug currently under ...
What are the tests for primary ovarian insufficiency? Many tests, see REI. Reproductive endocrinology md will confirm poi - ... cannot be used in primary ovarian failure. In primary ovarian failure the ovaries do not produce estrogen to cause ovulation ( ... Ovarian Insufficiency (Definition) "Primary ovarian insufficiency describes a spectrum of declining ovarian functions and ... Primary Ovarian Insufficiency (Definition) Premature ovarian failure is a loss of normal function of your ovaries before age 40 ...
... reduced bone mineral density and increased risk of cardiovascular disease related to estrogen deficiency. Approximately 5% to ... keywords = "Menopause, premature, Primary ovarian insufficiency, Primary ovarian insufficiency",. author = "Martin, {Lisa Arndt ... of women with primary ovarian insufficiency conceive and have a child. Women who develop primary ovarian insufficiency related ... of women with primary ovarian insufficiency conceive and have a child. Women who develop primary ovarian insufficiency related ...
Premature ovarian failure (POF) is a condition in which the menstrual cycle stops and the ovaries stop... ... Hormonally, POF is marked by abnormally low levels of estrogen and follicle stimulating hormone (FSH), which circulates at ... Primary Ovarian Insufficiency (POF) Definition - What does Primary Ovarian Insufficiency (POF) mean? Premature ovarian failure ... FertilitySmarts explains Primary Ovarian Insufficiency (POF). Ovarian failure is a natural part of the aging process and ...
Development a Predictive Nomogram for Primary Ovarian Insufficiency Status: Not yet recruiting ... Treatment may include growth hormone therapy for short stature and estrogen therapy to help stimulate sexual development. ...
Primary ovarian insufficiency(POI) happens when a womans ovaries stop working before she is 40. POI is different from ... Osteoporosis. The hormone estrogen helps keep bones strong. Without enough estrogen, women with POI often develop osteoporosis ... What is primary ovarian insufficiency (POI)?. Primary ovarian insufficiency (POI), also known as premature ovarian failure, ... Primary Ovarian Insufficiency (Hormone Health Network) * Primary Ovarian Insufficiency (POI) (National Institute of Child ...
Primary Purpose: Treatment. *Hormonal Assessment serum FSH level will be measured.. *Hormonal Assessment serum estrogen level ... Development a Predictive Nomogram for Primary Ovarian Insufficiency. *Primary Ovarian Insufficiency. Observational. *Guangzhou ... Ovarian Laparoscopic In Vivo Activation of Ovary for Premature Ovarian Insufficiency. *Primary Ovarian Insufficiency ... Draw the Primary Ovarian insufficiency normogram. *Verify and evaluate the evaluation of Primary Ovarian insufficiency ...
Learn about sources of estrogen and its functions. ... Estrogen is a hormone that both males and females produce. It ... In addition to menopause, estrogen therapy can also help resolve: *primary ovarian insufficiency ... Premarin, which contains estrogens from the urine of pregnant mares Estrogen therapy. Estrogen therapy can help manage ... This type of estrogen is present in the body after menopause. It is a weaker form of estrogen and one that the body can convert ...
Clinical trial for Premature ovarian failure , Turners Syndrome , Primary Ovarian Insufficiency: Phenotype and Optimal ... If initiated early, HRT may prevent estrogen-associated bone loss. Impact: Better understanding of POI may lead to improved ... Primary Ovarian Insufficiency: Phenotype and Optimal Treatment Brief description of study. This pilot study will observe the ... Background: Primary ovarian insufficiency (POI) is an enigmatic condition that affects ~1/10,000 women by age 20. Sometimes ...
Suspect primary ovarian insufficiency in women with unexplained menstrual abnormalities, infertility, or symptoms of estrogen ... Primary ovarian insufficiency has various causes (see Table: Common Causes of Primary Ovarian Insufficiency), including the ... Primary Ovarian Insufficiency (Premature Menopause; Hypergonadotropic Hypogonadism; Premature Ovarian Insufficiency; Premature ... If primary ovarian insufficiency is caused by an autoimmune disorder, women are at risk of potentially life-threatening primary ...
POI has been called premature ovarian failure and premature menopause. ... Primary ovarian insufficiency, or POI, is when the ovaries stop working normally before the age of 40. With POI, the ovary does ... Most women with POI need hormone treatment with estrogen. This can help reduce bone loss and other symptoms of reduced estrogen ... Primary Ovarian Insufficiency. What is primary ovarian insufficiency?. Primary ovarian insufficiency (POI) is when the ovaries ...
Discover the diagnosis, health risks, and treatment options associated with premature ovarian failure at hormone.org. ... HT combines estrogen and progesterone, another sex hormone. Together these two hormones mimic the natural balance of hormones ... What is primary ovarian insufficiency?. Primary ovarian insufficiency (POI), also called premature ovarian failure, occurs when ... Because women with POI have low levels of estrogen at a young age, several health problems are more common than in women ...
Estrogens are hormones responsible for female sexual development and function. Measuring estrogen levels can provide important ... An estrogen test measures the level of estrogens in blood, urine, or saliva. ... Primary ovarian insufficiency, a condition that causes a womans ovaries to stop working before she is 40 years old ... What is an estrogen test?. An estrogen test measures the level of estrogens in the blood or urine. Estrogen can also be ...
Discover the diagnosis, health risks, and treatment options associated with premature ovarian failure at hormone.org. ... Primary ovarian insufficiency (POI), also called premature ovarian failure, occurs when the ovaries have a decrease in estrogen ... Because women with POI have low levels of estrogen at a young age, several health problems are more common than in women ... Low estrogen early in life appears to increase the risk of heart attack as a woman ages. ...
... with primary ovarian insufficiency in public population with respect to the age of apparition the primary ovarian insufficiency ... Early sequelae of POI include vasomotor symptoms, vaginal dryness, mood swings and insomnia due to estrogen deficiency. Long- ... Hormone Replacement for Premature Ovarian Insufficiency Premature ovarian insufficiency (POI) is a term used to describe when a ... A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Insufficiency Patients ...
This is sometimes called premature ovarian failure, or primary ovarian insufficiency. The cause of premature ovarian failure is ... early menopause also have an increased risk of osteoporosis and cardiovascular disease because of their lowered oestrogen ... Premature ovarian failure can sometimes run in families. This might be the case if any of your relatives went through the ... Radiotherapy and chemotherapy can cause premature ovarian failure. This may be permanent or temporary. ...
Very low estrogen with a high FSH is a sign of primary ovarian insufficiency. ... What is primary ovarian insufficiency?. Primary ovarian insufficiency (sometimes called premature ovarian failure) occurs when ... Can primary ovarian insufficiency be prevented?. At this time, there is no way to prevent primary ovarian insufficiency. But ... What causes primary ovarian insufficiency?. Although the exact cause of primary ovarian insufficiency may be unknown, a genetic ...
ABSTRACT: Primary ovarian insufficiency describes a spectrum of declining ovarian function and reduced fecundity due to a ... Clinical risk factors for endometrial cancer, including but not limited to age, obesity, use of unopposed estrogen, specific ... In women with primary ovarian insufficiency, systemic hormone therapy (HT) is an effective approach to treat the symptoms of ... The sequelae of primary ovarian insufficiency include vasomotor symptoms, urogenital atrophy, osteoporosis and fracture, ...
ABSTRACT: Primary ovarian insufficiency describes a spectrum of declining ovarian function and reduced fecundity due to a ... Evidence is insufficient to conclude that long-term estrogen therapy or hormone therapy use improves cardiovascular outcomes. ... In women with primary ovarian insufficiency, systemic hormone therapy (HT) is an effective approach to treat the symptoms of ... The sequelae of primary ovarian insufficiency include vasomotor symptoms, urogenital atrophy, osteoporosis and fracture, ...
Detour: Primary Ovarian Insufficiency (POI). One way to get to menopause earlier than usual is a condition called POI. With POI ... and mood swings-all results of unevenly changing levels of ovarian hormones (estrogen) in your body. Read more about how youll ... Due to the continued decrease in estrogen levels during this time, symptoms like vaginal dryness and hot flashes may linger. ... Trip Tip: POI means lower estrogen levels, which means negative effects on your bone density and possibly your brain and sexual ...
Primary ovarian insufficiency: a more accurate term for premature ovarian failure. Clin Endocrinol (Oxf). 2008 Apr. 68(4):499- ... Aromatase catalyzes the conversion of androgen to estrogen. When estrogen synthesis cannot occur, increased levels of ... Spontaneous 46,XX primary ovarian insufficiency (POI), (also known as premature ovarian failure [POF] and premature menopause) ... For more detailed information, see Spontaneous Primary Ovarian Insufficiency and Premature Ovarian Failure. ...
"Primary Ovarian Insufficiency Is Not An Early Menopause". Julia R. Heiman, PhD (2009) "The Science of Sexuality Through ... "Cycle & Hormone Changes During Perimenopause: The Key Role of Ovarian Function". Thomas B. Clarkson, DVM (2006). "Estrogen ... "Menopause, Estrogens, and Lipoprotein Particles" Kenneth D. Setchell, PhD (2016). "The History and Basic Science Development of ... "Definition of Functionally Important Mechanistic Differences Among Selective Estrogen-Receptor Modulators". Henry G. Burger, MD ...
This is sometimes called premature ovarian failure, or primary ovarian insufficiency.. The cause of premature ovarian failure ... particularly the hormone oestrogen. ... What is Premature Ovarian Failure? Early menopause can happen ... Premature ovarian failure can sometimes run in families. This might be the case if any of your relatives went through the ... The condition - known as Premature Ovarian Failure (POF) - could cause a variety of conditions but for Lauren, now 26, the most ...
Chemotherapy can also cause primary ovarian insufficiency in women, which can lead to hot flashes, irregular periods and ... Radiation therapy can cause erectile dysfunction and other similar issues in men, as well as low estrogen levels in women that ... Chemotherapy, for instance, can decrease levels of estrogen and testosterone, ultimately lowering sex drive. ...
Primary Causes, Patient Concerns and Latest Treatments and Spiractin Reports and Side Effects. ... Primary Symptoms and Causes. What is Primary ovarian insufficiency (POI)?. Primary ovarian insufficiency (POI), also known as ... The hormone estrogen helps keep bones strong. Without enough estrogen, women with POI often develop osteoporosis. It is a bone ... How is Primary ovarian insufficiency (POI) treated?. Currently, there is no proven treatment to restore normal function to a ...
What is primary ovarian insufficiency (POI)?. Primary ovarian insufficiency (POI), also known as premature ovarian failure, ... The hormone estrogen helps keep bones strong. Without enough estrogen, women with POI often develop osteoporosis. It is a bone ... How is primary ovarian insufficiency (POI) treated?. Currently, there is no proven treatment to restore normal function to a ... What causes primary ovarian insufficiency (POI)?. In about 90 percent of cases, the exact cause of POI is unknown. ...
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