Esophageal Stenosis: A stricture of the ESOPHAGUS. Most are acquired but can be congenital.Myocutaneous Flap: A mass of tissue, including skin and muscle, that has been cut away from surrounding areas for transplantation.Caustics: Strong alkaline chemicals that destroy soft body tissues resulting in a deep, penetrating type of burn, in contrast to corrosives, that result in a more superficial type of damage via chemical means or inflammation. Caustics are usually hydroxides of light metals. SODIUM HYDROXIDE and potassium hydroxide are the most widely used caustic agents in industry. Medically, they have been used externally to remove diseased or dead tissues and destroy warts and small tumors. The accidental ingestion of products (household and industrial) containing caustic ingredients results in thousands of injuries per year.Esophagoscopy: Endoscopic examination, therapy or surgery of the esophagus.Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Coronary Stenosis: Narrowing or constriction of a coronary artery.Spinal Stenosis: Narrowing of the spinal canal.Tracheal StenosisCopyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Herpes Simplex: A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)Dilatation: The act of dilating.ArchivesAcyclovir: A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.Herpes Genitalis: Infection of the genitals (GENITALIA) with HERPES SIMPLEX VIRUS in either the males or the females.Afipia: A genus of gram-negative, oxidase-positive, nonfermentative rods which are motile by means of a single flagellum. Afipia felis and BARTONELLA HENSELAE are causative agents of CAT-SCRATCH DISEASE. (From Bergey's Manual of Determinative Bacteriology, 9th ed)Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.Pharyngeal Neoplasms: Tumors or cancer of the PHARYNX.Respiratory Tract NeoplasmsLaryngeal Neoplasms: Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.Otorhinolaryngologic Neoplasms: A general concept for tumors or cancer of any part of the EAR; the NOSE; the THROAT; and the PHARYNX. It is used when there is no specific heading.Pulmonary Medicine: A subspecialty of internal medicine concerned with the study of the RESPIRATORY SYSTEM. It is especially concerned with diagnosis and treatment of diseases and defects of the lungs and bronchial tree.Ambulatory Care: Health care services provided to patients on an ambulatory basis, rather than by admission to a hospital or other health care facility. The services may be a part of a hospital, augmenting its inpatient services, or may be provided at a free-standing facility.Nuclear Medicine Department, Hospital: Hospital department responsible for the administration and management of nuclear medicine services.Hospitals, Pediatric: Special hospitals which provide care for ill children.Gastroenterology: A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Nuclear Medicine: A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds in a pharmaceutical form.Manuscripts as Topic: Compositions written by hand, as one written before the invention or adoption of printing. A manuscript may also refer to a handwritten copy of an ancient author. A manuscript may be handwritten or typewritten as distinguished from a printed copy, especially the copy of a writer's work from which printed copies are made. (Webster, 3d ed)Pediatrics: A medical specialty concerned with maintaining health and providing medical care to children from birth to adolescence.Celiac Disease: A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Developmental Biology: The field of biology which deals with the process of the growth and differentiation of an organism.Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).Czech Republic: Created 1 January 1993 as a result of the division of Czechoslovakia into the Czech Republic and Slovakia.Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.Valsalva Maneuver: Forced expiratory effort against a closed GLOTTIS.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Esophageal Diseases: Pathological processes in the ESOPHAGUS.Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.Metals: Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)Palliative Care: Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)VietnamRheumatology: A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis.Cardiac Surgical Procedures: Surgery performed on the heart.Public Facilities: An area of recreation or hygiene for use by the public.Cellular Phone: Analog or digital communications device in which the user has a wireless connection from a telephone to a nearby transmitter. It is termed cellular because the service area is divided into multiple "cells." As the user moves from one cell area to another, the call is transferred to the local transmitter.Rift Valley Fever: An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.Rift Valley fever virus: A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.

Retrograde esophageal balloon dilatation for caustic stricture in an outpatient clinic setting. (1/251)

Caustic injury to the esophagus, with resultant esophageal stricture, is a challenge for the surgeon. These strictures require multiple esophageal dilatations, which are usually performed under general anesthesia and frequently under fluoroscopic control. Because of the risks of multiple general anesthetics and frequent radiation, a technique is described for retrograde esophageal balloon dilatation in an outpatient clinic setting without a general anesthetic or fluoroscopic control.  (+info)

Correction of bone marrow failure in dyskeratosis congenita by bone marrow transplantation. (2/251)

Dyskeratosis congenita is recognized by its dermal lesions and constitutional aplastic anemia in some cases. We report successful allogeneic bone marrow transplantation in two siblings with this disease from their sister, and their long term follow-up. We used reduced doses of cyclophosphamide and busulfan for conditioning instead of total body irradiation. Also, we report late adverse effects of transplantation which are not distinguishable from the natural course of disease.  (+info)

Reduction of unsafe eating in a patient with esophageal stricture. (3/251)

Previous research has demonstrated the efficacy of behavioral interventions in teaching self-feeding skills as well as in reducing inappropriate self-feeding behavior. The purpose of this study was to extend previous research on the use of prompting and reinforcement in reducing unsafe eating behaviors to the treatment of an adolescent with developmental disabilities and esophageal stricture. A behavioral assessment and treatment using prompting and reinforcement were shown to be effective in decreasing bite rate, decreasing bite size, and increasing the number of chews per bite.  (+info)

Surgical treatment of oesophageal obstruction after ingestion of a granular laxative. (4/251)

A case of oesophageal obstruction after ingestion of a granular laxative in a 91-year-old man is presented. There was no predisposing oesophageal disease. The severity of obstruction prevented endoscopic clearance and the patient required gastrotomy and manual disimpaction of the lower oesophagus.  (+info)

Omeprazole therapy decreases the need for dilatation of peptic oesophageal strictures. (5/251)

BACKGROUND: Better control of gastric acid secretion with omeprazole appeared to decrease the need for dilatation of oesophageal strictures complicating gastro-oesophageal reflux disease in our hospital-based endoscopy service. AIM: To investigate whether the perceived decrease in the need for oesophageal dilatation could be documented from endoscopy records, and, if confirmed, whether this could be related to the treatment used. PATIENTS AND METHODS: Retrospective study of the records of 69 patients who had peptic oesophageal strictures dilated, followed by treatment with acid inhibition for at least 6 months. Mean duration of follow-up was 3.9 years during treatment with H2-receptor antagonists and 2.1 years while on omeprazole (258 and 78 patient-years, respectively). Re-dilatation rates were compared between those treated with H2-receptor antagonists or omeprazole. RESULTS: There has been a significant decrease in dilatations performed for gastro-oesophageal reflux induced strictures (P<0.001), while dilatation rates for other indications remained constant. Treatment with omeprazole not only decreased the need for further dilatations, but also prolonged the mean time between any further dilatations to 26.3 months compared to 9.3 months for those on an H2-receptor antagonist (P<0.0001). CONCLUSIONS: Following dilatation of peptic oesophageal strictures, treatment with omeprazole in place of an H2-blocker significantly decreases the need for repeat dilatation.  (+info)

Gastric cancer and other endoscopic diagnoses in patients with benign dyspepsia. (6/251)

BACKGROUND: It has been suggested that endoscopy could be replaced with non-invasive assessment of helicobacter status in the initial work up of young dyspeptic patients without sinister symptoms. AIMS: To determine the incidence of gastro-oesophageal malignancy in young dyspeptic patients. METHODS: The Alberta Endoscopy Project captured clinical and demographic data on all endoscopies performed from April 1993 to February 1996 at four major adult hospitals in Alberta. The endoscopic and histological diagnosis in a subgroup of patients under 45 years of age without alarm symptoms that had undergone gastroscopy was reviewed. In addition, a random list of 200 patients was generated and their medical records reviewed in order to assess the proportion with symptoms suitable for a non-invasive management strategy. RESULTS: Gastroscopy was performed in 7004 patients under 45 years. In 3634 patients (56% female) alarm type symptoms were absent; 78.9% of patients had symptoms amenable to a non-invasive initial approach, giving a corrected sample size of 2867 patients (correction factor 0.789). Three gastric cancers, one case of moderate dysplasia, 10 biopsy proved cases of Barrett's oesophagus, and 19 oesophageal strictures/rings were detected within this sample. The corrected prevalence of gastric cancer in this select population was 1.05 per thousand patients. DISCUSSION: Endoscopy yielded three gastric cancers in this sample of under 45 year old dyspeptic patients without sinister symptoms. While initial non-invasive screening with one-week triple therapy for helicobacter positive individuals is unlikely to have a detrimental outcome the physician is advised to consider endoscopy in patients with persisting, recurrent, or sinister symptoms.  (+info)

Esophageal obstruction in horses: a retrospective study of 34 cases. (7/251)

The major purpose of this investigation was to describe the causes, possible complications, and prognoses of horses with esophageal obstruction. Of 34 cases presenting with esophageal obstruction, 28 cases were due to impaction of ingesta. Obstruction due to pre-existing esophageal disease occurred in 4 horses with megaesophagus, in 1 horse with stricture in the upper third of the esophagus, and in 1 horse with esophageal diverticulum. There was no significant difference in the contamination of the trachea between horses that subsequently developed aspiration pneumonia and those that did not. The duration of esophageal obstruction prior to admission was significantly longer in horses that developed aspiration pneumonia (median 18, range 2-48 h) than in those horses that did not (median 4, range 0.5-48 h). Although the obstruction was relieved in all 34 horses, 4 were euthanized because of recurring obstruction due to megaesophagus (n = 2), esophageal diverticulum (n = 1), and esophageal stricture (n = 1).  (+info)

Improvement in lower esophageal sphincter pressure following surgery for complicated gastroesophageal reflux. (8/251)

A comparison was made of the pre- and postoperative lower esophageal sphincter (LES) pressures in nine patients undergoing a posterior gastropexy for complicated gastroesophageal reflux. LES pressure was increased from 4.4 plus or minus 0.4 mm Hg to 13.9 plus or minus 0.5 mm Hg following surgery (p less than .01). The ratio of the change in LES pressure compared to the change in gastric pressure during increases in intra-abdominal pressure delta S/delta G, was 0.59 plus or minus 0.05 preoperatively and 0.94 plus or minus .01 postoperatively (p less than .01). All patients were asymptomatic after surgery. Both the resting LES pressure and the S/G ratio following surgery were significantly less than the comparable values obtained in an age-matched control population (p less than .01). These studies suggest that the clinical improvement following surgery for gastroesophageal reflux may be due to the increase in resting LES pressure and the improved response of the LES to increased intra-abdominal pressure.  (+info)

  • This segment should always be located above the upper margin of the stenosis, in the healthy tissue. (
  • GERD can also be caused by pyloric stenosis, or motility disorder wherein the gastric emptying time of the stomach contents to the duodenum is slower than the normal. (
  • CSI in 2 of cases it has been recorded as acid ingestion who was also accompanied with pyloric stenosis and the majority of cases (71.9%) were alkali which is mostly used as whitening liquid (Vitex) for clothes. (
  • Most infants with recurrent apnoea and bradycardia do not have gastro-oesophageal reflux (GOR). (
  • Investigation and management of GOR in the neonatal nursery should be reserved for those infants in whom the reflux is considered to be pathological gastro-oesophageal reflux disease (GORD). (
  • Gastro-oesophageal reflux (GOR) is the spontaneous effortless regurgitation of gastric contents into the oesophagus that may or may not result in vomiting. (
  • mRNA expression of inducible nitric oxide synthase, endothelial nitric oxide synthase and vascular endothelial growth factor in esophageal mucosa biopsy specimens from patients with reflux esophagitis. (
  • As esophageal adenocarcinoma develops in a background of Barrett's esophagus secondary to reflux disease, it is possible that inflammatory mediators like NO may be important in esophageal cancer development. (
  • Some degree of back-flow of gastric or duodenal contents into the esophagus is normal in both adults and children but excessive reflux occurs due to incompetent lower esophageal sphincter (LES) or the opening from the esophagus going to the stomach. (
  • Introduction: Eosinophilic esophagitis (EE) is an entity characterized by esophageal symptoms with the presence of dense eosinophilia, in the absence of reflux disease excluded by pHmetry or lack of response to treatment with proton pump inhibitor. (
  • Radiograph from a small-bowel series revealed a thin fi lling defect with a dilated duodenal bulb in the distal region of the second portion of the duodenum, suggesting a duodenal web, and endoscopy revealed duodenal stenosis. (
  • [ 1 ] Similarly, Bruzzi et al reported that emergency CT outperforms endoscopy in predicting esophageal stricture formation after caustic ingestion. (
  • In HDE the progression of the endoscope was not possible by the existence of stenosis, in a mucosa with traqueiform rings. (
  • Hyers tm antithrombotic therapy in patients with severe mitral stenosis is possible with prolonged conduction of the most common in children with hearing loss expected. (
  • 1.Thestent will engender a continued gentle radial tensile force, acting on the inner wall of non vascular cavities to expand the stenosis gradually and rebuilt the unobstructed passage. (
  • The Har-El Pharyngeal Salivary Bypass Tube allows the surgeon to handle a wider variety of indications for treatment of esophageal fistulae. (
  • One of the outcomes is oesophageal stricture, the first line treatment is dilatation Savary Gillard dilatators have the highest success rate of 92.5% compared with other surgical procedures, although it is a long term treatment as the recurrence of stricture is more than expected after dilatation. (
  • VIDEO A11-48: Baseline angiogram showing a total occlusion of the proximal LAD within the drug-eluting stent and a significant stenosis at the origin of the LCx. (
  • CellSeed completed clinical trials of the epithelial cell sheet for esophageal regeneration in the first quarter of fiscal 2019. (
  • Thoracoscopic oesophago-oesophagostomy in the prone position for oesophageal stenosis caused by dilated azygos vein in polysplenia-associated heterotaxy. (
  • It is generally accepted that oesophageal stricture is the most common complication and causes significant morbidity. (
  • CONCLUSIONS: This study provides a benchmark for current outcomes and complication rates following OA-TOF repair, with oesophageal stricture causing significant morbidity. (