Diseases
Esophageal NeoplasmsPancreatic Neoplasms
Esophageal Neoplasms
Tumors or cancer of the ESOPHAGUS.
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Multiple target sites of allelic imbalance on chromosome 17 in Barrett's oesophageal cancer. (1/4657)

Twelve Barrett's adenocarcinomas have been analysed for the occurrence of allelic imbalance (LOH) on chromosome 17 using 41 microsatellite markers. This study provides evidence for 13 minimal regions of LOH, six on 17p and seven on 17q. Four of these centre in the vicinity of the known tumour suppressor genes (TSGs) TP53 (17p13.1), NFI (17q11.2), BRCA1 (17q21.1), and a putative TSG (17p13.3). The tumours all displayed relatively small regions of LOH (1-10 cM), and in several tumours extensive regions of LOH were detected. One tumour displayed only two very small regions of LOH; 17p11.2 and 17p13.1. The frequency of allelic imbalance has been calculated based on the LOH encompassing only one minimal region, and based on all the LOH observations. By both evaluations the highest LOH frequencies were found for regions II (p53), III (17p13.1 centromeric to p53), IV (17p12), V (17p11.2) and VII (NF1, 17q11.2). Our data supports the existence of multiple TSGs on chromosome 17 and challenges the view that p53 is the sole target of LOH on 17p in Barrett's adenocarcinoma.  (+info)

Effects of soybean oil emulsion and eicosapentaenoic acid on stress response and immune function after a severely stressful operation. (2/4657)

OBJECTIVE: To investigate the effects of soybean oil emulsion and oral or enteral administration of eicosapentaenoic acid (EPA) on stress response, cytokine production, protein metabolism, and immune function after surgery for esophageal cancer. SUMMARY BACKGROUND DATA: It has been reported that safflower oil, rich in n-6 polyunsaturated fatty acid (n-6 PUFA), affects the survival rate of septic animals and decreases the immune function. It has also been reported that the administration of fish oil, in contrast, reduces these stress responses and stress-induced immunosuppression. In humans, the effects of soybean oil emulsion and the administration of EPA on stress response and immune function after surgery have not been established. METHODS: Patients who underwent esophagectomy with thoracotomy were divided into three groups. Seven patients were fed by total parenteral nutrition (TPN) with soybean oil emulsion, which accounted for 20% of total calories. Seven patients were given oral or enteral administration of 1.8 g/day EPA, in addition to TPN with soybean oil emulsion. Nine patients served as the control group; these patients received fat-free TPN. Serum interleukin-6 (IL-6), C-reactive protein, concanavalin A (con A)- or phytohemagglutinin (PHA)-stimulated lymphocyte proliferation, natural killer cell activity, and stress hormones were measured. RESULTS: The postoperative level of serum IL-6 was significantly higher in the group receiving soybean oil emulsion than in the fat-free group. Oral or enteral supplementation of EPA with soybean oil emulsion significantly reduced the level of serum IL-6 compared with the patients receiving soybean oil emulsion. Con A- or PHA-stimulated lymphocyte proliferation decreased significantly on postoperative day 7 in all groups of patients. The supplementation of EPA with soybean oil emulsion significantly improved the lymphocyte proliferation and natural killer cell activity on postoperative day 21 compared with the group receiving soybean oil emulsion. CONCLUSIONS: Soybean oil emulsion amplifies, and the supplementation of EPA reduces, the stress response and stress-induced immunosuppression.  (+info)

Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. (3/4657)

Human UDP-glucuronosyltransferases (UGTs) are expressed in a tissue-specific fashion in hepatic and extrahepatic tissues [Strassburg, Manns and Tukey (1998) J. Biol. Chem. 273, 8719-8726]. Previous work suggests that these enzymes play a protective role in chemical carcinogenesis [Strassburg, Manns and Tukey (1997) Cancer Res. 57, 2979-2985]. In this study, UGT1 and UGT2 gene expression was investigated in human oesophageal epithelium and squamous-cell carcinoma in addition to the characterization of individual UGT isoforms using recombinant protein. UGT mRNA expression was characterized by duplex reverse transcriptase-PCR analysis and revealed the expression of UGT1A7, UGT1A8, UGT1A9 and UGT1A10 mRNAs. UGT1A1, UGT1A3, UGT1A4, UGT1A5 and UGT1A6 transcripts were not detected. UGT2 expression included UGT2B7, UGT2B10 and UGT2B15, but UGT2B4 mRNA was absent. UGT2 mRNA was present at significantly lower levels than UGT1 transcripts. This observation was in agreement with the analysis of catalytic activities in oesophageal microsomal protein, which was characterized by high glucuronidation rates for phenolic xenobiotics, all of which are classical UGT1 substrates. Whereas UGT1A9 was not regulated, differential regulation of UGT1A7 and UGT1A10 mRNA was observed between normal oesophageal epithelium and squamous-cell carcinoma. Expression and analysis in vitro of recombinant UGT1A7, UGT1A9, UGT1A10, UGT2B7 and UGT2B15 demonstrated that UGT1A7, UGT1A9 and UGT1A10 catalysed the glucuronidation of 7-hydroxybenzo(alpha)pyrene, as well as other environmental carcinogens, such as 2-hydroxyamino-1-methyl-6-phenylimidazo-(4, 5-beta)-pyridine. Although UGT1A9 was not regulated in the carcinoma tissue, the five-fold reduction in 7-hydroxybenzo(alpha)pyrene glucuronidation could be attributed to regulation of UGT1A7 and UGT1A10. These data elucidate an individual regulation of human UGT1A and UGT2B genes in human oesophagus and provide evidence for specific catalytic activities of individual human UGT isoforms towards environmental carcinogens that have been implicated in cellular carcinogenesis.  (+info)

Expression of pyrimidine nucleoside phosphorylase mRNA plays an important role in the prognosis of patients with oesophageal cancer. (4/4657)

To clarify the significance of the expression of pyrimidine nucleoside phosphorylase (PyNPase) mRNA as a predictive factor for the prognosis of patients with oesophageal carcinoma, the PyNPase mRNA in the tumours and normal tissues from 55 resected cases of oesophageal carcinoma was examined by a reverse transcription polymerase chain reaction (RT-PCR). As a result, a positive correlation was observed between the tumour/normal (T/N) ratio of the expression of PyNPase mRNA by RT-PCR and that of the enzyme activity of PyNPase based on the findings of an enzyme linked immunosolvent assay (r = 0.594, P = 0.009). The T/N ratio of the expression of PyNPase mRNA was significantly higher in the cases with lymph vessel invasion (P = 0.013), lymph node metastasis (P = 0.0016), and an advanced stage of the disease (P = 0.021) than those without these factors. The patients with a higher T/N ratio of PyNPase mRNA showed significantly worse prognosis than those with a lower T/N ratio (P = 0.023 with log-rank tests). A multivariate analysis for the cumulative survival rates revealed that a high T/N ratio of the expression of PyNPase mRNA was independently related to a poor prognosis. These findings suggested that the determination of PyNPase mRNA by RT-PCR thus appears to be a new useful parameter for identifying both a poor prognosis and a highly malignant potential of oesophageal carcinoma.  (+info)

Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas. (5/4657)

The protein expression patterns of normal, metaplastic and malignant oesophageal tissues were analysed by two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) to identify changes associated with Barrett's metaplasia and transformation to oesophageal adenocarcinoma. Heat-shock protein 27 (Hsp27), a small heat-shock protein which is protective against cytotoxic stresses, was abundant in normal oesophagus. However, Hsp27 expression was markedly lower in Barrett's metaplasia and oesophageal adenocarcinomas. This was confirmed by immunohistochemical analysis. Hsp27 protein was most highly expressed in the upper layers of squamous epithelium and exhibited a pattern of expression that corresponded with the degree of squamous maturation. Northern and Southern analysis demonstrated Hsp27 to be regulated at the level of mRNA transcription or abundance. Normal oesophageal tissues were examined for gender differences in Hsp27 expression. Women expressed fourfold higher levels of Hsp27 mRNA, however, this difference was not appreciable in protein expression. Hsp27 protein was inducible by heat shock in Barrett's adenocarcinoma cell lines and an immortalized oesophageal epithelial cell line (HET-1A), but not by oestradiol. These results demonstrate abundant constitutive expression of the stress-response protein Hsp27 in the normal oesophagus, and suggest that low-level expression in Barrett's metaplasia may be one factor which may influence susceptibility to oesophageal adenocarcinoma development.  (+info)

Detection of occult lymph node metastases in esophageal cancer by minimally invasive staging combined with molecular diagnostic techniques. (6/4657)

BACKGROUND AND OBJECTIVES: Lymph node metastases are the most important prognostic factor in patients with esophageal cancer. Histologic examination misses micrometastases in up to 20% of lymph nodes evaluated. In addition, non-invasive imaging modalities are not sensitive enough to detect small lymph nodes metastases. The objective of this study was to investigate the use of reverse transcriptase-polymerase chain reaction (RT-PCR) of messenger RNA (mRNA) for carcinoembryonic antigen (CEA) to increase the detection of micrometastases in lymph nodes from patients with esophageal cancer. METHODS: RT-PCR of CEA mRNA was performed in lymph nodes from patients with malignant and benign esophageal disease. Each specimen was examined histopathologically and by RT-PCR and the results were compared. RESULTS: Metastases were present in 29 of 60 (48%) lymph nodes sample by minimally invasive staging from 13 patients with esophageal cancer when examined histopathologically. RT-PCR identified nodal metastases in 46 of these 60 (77%) samples. RT-PCR detected CEA mRNA in all 29 histologically positive samples and in 17 histologically negative lymph nodes. All lymph nodes from patients with benign disease (n = 15) were negative both histopathologically and by RT-PCR. The stage of two patients was reclassified based on the RT-PCR results, which identified lymph node spread undetected histopathologically. Both of these patients developed recurrent disease after resection of the primary tumor. CONCLUSIONS: RT-PCR is more sensitive than histologic examination in the detection of lymph node metastases in esophageal cancer and can lead to diagnosis of a more advanced stage in some patients. The combination of minimally invasive surgical techniques in combination with new molecular diagnostic techniques may improve our ability to stage cancer patients.  (+info)

G-protein gamma 7 is down-regulated in cancers and associated with p 27kip1-induced growth arrest. (7/4657)

We previously identified and cloned human G protein gamma 7 (G-gamma 7) gene, which is down-regulated in pancreatic cancer. We examined G-gamma 7 expression in other gastrointestinal tract cancers. In 24 of 30 patients with gastrointestinal tract cancer, Northern blot assay and immunohistochemical staining revealed significantly lower G-gamma 7 expression in tumors than in normal tissues from the same patients. Semiquantitative reverse transcription PCRs also showed lower G-gamma 7 expression in tumors than in corresponding normal tissues in 69 of 90 patients. To examine the biological role of G-gamma 7 in cancer, the G-gamma 7 cDNA was transfected into a human esophageal carcinoma cell line, KYSE150, that lacks G-gamma 7 expression. G-gamma 7 expression suppressed cell growth and tritiated-thymidine uptake when cells were confluent G-gamma 7 expression also suppressed tumorigenicity in BALB/c nude mice until 3 weeks after transplantation. G-gamma 7 expression increased the Go/G1 population and decreased the S phase population when cells were at high density. We confirmed that this change was associated with p27K1P1 expression. These findings suggest that human G-gamma 7 is associated with p27kip1-induced growth arrest and may be a therapeutic target in cancers.  (+info)

Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. (8/4657)

BACKGROUND: The causes of adenocarcinomas of the esophagus and gastric cardia are poorly understood. We conducted an epidemiologic investigation of the possible association between gastroesophageal reflux and these tumors. METHODS: We performed a nationwide, population-based, case-control study in Sweden. Case ascertainment was rapid, and all cases were classified uniformly. Information on the subjects' history of gastroesophageal reflux was collected in personal interviews. The odds ratios were calculated by logistic regression, with multivariate adjustment for potentially confounding variables. RESULTS: Of the patients interviewed, the 189 with esophageal adenocarcinoma and the 262 with adenocarcinoma of the cardia constituted 85 percent of the 529 patients in Sweden who were eligible for the study during the period from 1995 through 1997. For comparison, we interviewed 820 control subjects from the general population and 167 patients with esophageal squamous-cell carcinoma. Among persons with recurrent symptoms of reflux, as compared with persons without such symptoms, the odds ratios were 7.7 (95 percent confidence interval, 5.3 to 11.4) for esophageal adenocarcinoma and 2.0 (95 percent confidence interval, 1.4 to 2.9) for adenocarcinoma of the cardia. The more frequent, more severe, and longer-lasting the symptoms of reflux, the greater the risk. Among persons with long-standing and severe symptoms of reflux, the odds ratios were 43.5 (95 percent confidence interval, 18.3 to 103.5) for esophageal adenocarcinoma and 4.4 (95 percent confidence interval, 1.7 to 11.0) for adenocarcinoma of the cardia. The risk of esophageal squamous-cell carcinoma was not associated with reflux (odds ratio, 1.1; 95 percent confidence interval, 0.7 to 1.9). CONCLUSIONS: There is a strong and probably causal relation between gastroesophageal reflux and esophageal adenocarcinoma. The relation between reflux and adenocarcinoma of the gastric cardia is relatively weak.  (+info)

SESC - Superficial Esophageal Squamous-Cell Carcinoma | AcronymFinderSESC - Superficial Esophageal Squamous-Cell Carcinoma | AcronymFinder
How is Superficial Esophageal Squamous-Cell Carcinoma abbreviated? SESC stands for Superficial Esophageal Squamous-Cell Carcinoma. SESC is defined as Superficial Esophageal Squamous-Cell Carcinoma very rarely.
https://www.acronymfinder.com/Superficial-Esophageal-Squamous_Cell-Carcinoma-
Knockdown of C1GalT1 inhibits radioresistance of human esophageal cancer cells through modifying β1-integrin glycosylation ...Knockdown of C1GalT1 inhibits radioresistance of human esophageal cancer cells through modifying β1-integrin glycosylation ...
Radiotherapy has played a limited role for the treatment of human esophageal cancer owing to the risk of tumor radioresistance. Core 1 β1, 3-galactosyltransferase (C1GalT1), which catalyzes the formation of core 1 O-glycan structures, is frequently overexpressed during tumorigenesis. However, the exact effects and mechanisms of C1GalT1 in the radioresistance of esophageal cancer remain unclear. In this study, Public databases and our data revealed that C1GalT1 expression was up-regulated in esophageal cancer tissues and was associated with poor survival. Upon irradiation, we found that esophageal cancer cells with high levels of C1GalT1 could tolerate cell death and had increased resistance to radiotherapy. Irradiation also promoted the expression of C1GalT1 and core 1 O-glycan structures. C1GalT1 knockdown increased the radiosensitivity of esophageal cancer cells, and attenuated irradiation-enhanced migration and invasion. Mechanistic investigations showed that C1GalT1 modified O-glycan ...
https://www.jcancer.org/v09p2666
Expression of Nucleostemin, epidermal growth factor and epidermal growth factor receptor in human esophageal squamous cell...
To determine the expression of nucleostemin (NS), epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) mRNA in human esophageal squamous cell carcinoma (ESCC) tissues and their association in a human ESCC cell line. The expression of NS, EGF and EGFR mRNA was determined in paired normal esophageal and ESCC tissues of 62 patients using in situ hybridization. The association between NS and EGF or EGFR was examined using immunoblotting and real time polymerase chain reaction in a human ESCC cell line transfected with NS siRNA or treated with a selective EGFR inhibitor. In normal esophageal and ESCC tissues, the positive detection rates were 21.0% (13/62) and 69.4% (43/62) for NS mRNA staining, 40.3% (25/62) and 77.4% (48/62) for EGF mRNA staining, and 30.6% (19/62) and 75.8% (41/62) for EGFR mRNA staining, respectively. These results indicated that NS, EGF and EGFR mRNA expression was upregulated mostly in ESCC tissues. Moreover, the expression of NS, EGF and EGFR mRNA was ...
http://connection.ebscohost.com/c/articles/48156743/expression-nucleostemin-epidermal-growth-factor-epidermal-growth-factor-receptor-human-esophageal-squamous-cell-carcinoma-tissues
Advanced Esophageal Squamous Cell Carcinoma (ESCC) | HCP | KEYTRUDA® (pembrolizumab)Advanced Esophageal Squamous Cell Carcinoma (ESCC) | HCP | KEYTRUDA® (pembrolizumab)
Health care professionals may find information about advanced esophageal squamous cell carcinoma (ESCC) and KEYTRUDA® (pembrolizumab).
https://www.keytrudahcp.com/esophageal-carcinoma/first-line-combination-therapy/
Figure 7 from ADAM10 mediates the cell invasion and metastasis of human esophageal squamous cell carcinoma via regulation of E...Figure 7 from ADAM10 mediates the cell invasion and metastasis of human esophageal squamous cell carcinoma via regulation of E...
Figure 7. Quantitative real‑time PCR and western blot analysis were used to - ADAM10 mediates the cell invasion and metastasis of human esophageal squamous cell carcinoma via regulation of E-cadherin activity.
https://www.semanticscholar.org/paper/ADAM10-mediates-the-cell-invasion-and-metastasis-o-Ma-Zhang/c16efadce3ec529369f43c9f00af6825aa159264/figure/6
Molecular pathogenesis of human esophageal squamous cell carcinomas</em>...Molecular pathogenesis of human esophageal squamous cell carcinomas</em>...
TY - CONF. T1 - Molecular pathogenesis of human esophageal squamous cell carcinomas. AU - Tang, Cheuk On. AU - Hu, Y.C.. AU - Law, B.F.. AU - Wong, K.Y.. AU - Hu, L.. AU - Guan, X.Y.. AU - Srivastava, G.. PY - 2002. Y1 - 2002. M3 - Conference presentation (not published in journal/proceeding/book). T2 - Hong Kong International Cancer Congress. Y2 - 1 January 2002. ER - ...
https://research.polyu.edu.hk/en/publications/molecular-pathogenesis-of-human-esophageal-squamous-cell-carcinom
Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis | springermedizin.deTargeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis | springermedizin.de
Esophageal squamous cell carcinoma (ESCC) is one of the most frequently diagnosed cancers in developing countries, especially in Eastern Asia [ 1 ].
https://www.springermedizin.de/targeting-mcl-1-sensitizes-human-esophageal-squamous-cell-carcin/12488952?fulltextView=true
北京大学医学部机构知识库([email protected]): Efficacy of paclitaxel plus cisplatin in advanced esophageal squamous cell cancer: Further analysis of...
Gong, Jifang.,Zhang, Xiaodong.,Lu, Ming.,Li, Yan.,Li, Jie.,...&Shen, Lin.(2013).Efficacy of paclitaxel plus cisplatin in advanced esophageal squamous cell cancer: Further analysis of single center, prospective study..JOURNAL OF CLINICAL ONCOLOGY,suppl.S(15 ...
http://ir.bjmu.edu.cn/handle/400002259/64554
Oesophageal Cancer - Novel Targets for Therapy : With focus on Hsp90, EGFR, LRIG, microtubule and telomeraseOesophageal Cancer - Novel Targets for Therapy : With focus on Hsp90, EGFR, LRIG, microtubule and telomerase
Oesophageal cancer is a malignant and aggressive disease with very poor survival. The aim of this thesis was to evaluate novel therapeutic targets in oesophageal cancer.. In paper I, Hsp90 was expressed in all 81 oesophageal cancer tissues and also in nine oesophageal cancer cell lines. A specific Hsp90 inhibitor, 17-AAG, could efficiently inhibit cell proliferation, cell survival and sensitise oesophageal cancer cells to gamma photon irradiation. By inhibition of Hsp90 using 17-AAG, EGFR- and IGF-1R-mediated signalling was downregulated.. In paper II, tumour samples from 80 oesophageal cancer patients were investigated for the expression of EGFR and LRIG1-3. Based on a total score of intensity and expression fraction a trend towards survival differences was found for LRIG2 (p=0.18) and EGFR (p=0.09). Correlation analysis revealed a correlation between expression of EGFR and LRIG3 (p=0.0007). Significant correlations were found between LRIG1 mRNA expression levels and sensitivity to cisplatin (r ...
http://www.diva-portal.org/smash/record.jsf?pid=diva2:414126
MicroRNA‑544 inhibits esophageal squamous cell carcinoma cell proliferation and enhances sensitivity to cisplatin by repressing...
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies worldwide. MicroRNA (miRNA)‑544 is an important cancer‑associated RNA that is downregulated in multiple types of cancer. However, the role of miR‑544 in ESCC progression remains unknown. In the present study, miR‑544 expression level was determined via RT‑qPCR in 30 pairs of ESCC and adjacent normal tissues and in a panel of ESCC cell lines. Cell proliferation and cell apoptosis were assessed by MTT and flow cytometry assays. Luciferase reporter assay and western blot analysis were conducted to verify E2F transcription factor 5 (E2F5), an oncogene in ESCC, as a novel target gene of miR‑544. The results illustrated that miR‑544 is frequently downregulated in ESCC tissues and cell lines. Overexpression of miR‑544 in ESCC cells resulted in decreased cell proliferation and increased cell apoptosis. Thus, E2F5 was identified as a target of miR‑544, and its expression was negatively correlated with ...
https://tessera.spandidos-publications.com/ol/18/4/4203/abstract
Metformin Induces Human Esophageal Carcinoma Cell Pyroptosis by Target by Lu Wang, Kai Li et al.Metformin Induces Human Esophageal Carcinoma Cell Pyroptosis by Target by Lu Wang, Kai Li et al.
Evasion of apoptosis is a major contributing factor to the development of chemo- and radiotherapy resistance. Therefore, activation of non-apoptotic programmed cell death (PCD) could be an effective alternative against apoptosis-resistant cancers. In this study, we demonstrated in vitro and in vivo that metformin can induce pyroptosis, a non-apoptotic PCD, in esophageal squamous cell carcinoma (ESCC), a commonly known chemo-refractory cancer, especially at its advanced stages. Proline-, glutamic acid- and leucine-rich protein-1 (PELP1) is a scaffolding oncogene and upregulated PELP1 in advanced stages of ESCC is highly associated with cancer progression and patient outcomes. Intriguingly, metformin treatment leads to gasdermin D (GSDMD)-mediated pyroptosis, which is abrogated by forced expression of PELP1. Mechanistically, metformin induces pyroptosis of ESCC by targeting miR-497/PELP1 axis. Our findings suggest that metformin and any other pyroptosis-inducing reagents could serve as alternative
https://digitalcommons.pcom.edu/scholarly_papers/1976/
High levels of angiogenesis are associated with poor prognosis and a | High-Throughput Screen for the Chemical Inhibitors
High levels of angiogenesis are associated with poor prognosis and a highly invasive phenotype in esophageal squamous carcinoma. and significantly decreased NF-B signaling pathway. This study suggests that CCR7 plays WZ8040 an important pro-angiogenic role in esophageal squamous carcinoma via a mechanism linked to activation of the NF-B pathway; CCR7 may represent a potential target for anti-angiogenic therapy in esophageal squamous carcinoma. Keywords: CCR7, esophageal squamous carcinoma, angiogenesis, VEGF Introduction Esophageal squamous cell carcinoma (ESCC) is usually one of the most aggressive tumors and is usually also the most common cause of esophagus malignancy deaths WZ8040 worldwide [1]. Most of individuals showing with ESCC are diagnosed with advanced disease, due to the late emergence of clinical symptoms. In particular, the presence of regional attack, distant metastasis and tumor-induced angiogenesis show highly malignant potential in esophageal carcinoma patients [2]. Although ...
http://acancerjourney.info/index.php/2018/01/08/high-levels-of-angiogenesis-are-associated-with-poor-prognosis-and-a/
angiogenesis | High-Throughput Screen for the Chemical Inhibitors
High levels of angiogenesis are associated with poor prognosis and a highly invasive phenotype in esophageal squamous carcinoma. and significantly decreased NF-B signaling pathway. This study suggests that CCR7 plays WZ8040 an important pro-angiogenic role in esophageal squamous carcinoma via a mechanism linked to activation of the NF-B pathway; CCR7 may represent a potential target for anti-angiogenic therapy in esophageal squamous carcinoma. Keywords: CCR7, esophageal squamous carcinoma, angiogenesis, VEGF Introduction Esophageal squamous cell carcinoma (ESCC) is usually one of the most aggressive tumors and is usually also the most common cause of esophagus malignancy deaths WZ8040 worldwide [1]. Most of individuals showing with ESCC are diagnosed with advanced disease, due to the late emergence of clinical symptoms. In particular, the presence of regional attack, distant metastasis and tumor-induced angiogenesis show highly malignant potential in esophageal carcinoma patients [2]. Although ...
http://acancerjourney.info/index.php/tag/angiogenesis/
E-GEOD-53938 - The Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites (ChIP-seq KYSE150 cell line...
We have mapped binding sites for the histone demethylase, JMJD2C/KDM4C/GASC1, and the effect of JMJD2C depletion on H3K9me3 and H3K36me3 distributions in KYSE150 cells. The human esophageal carcinoma cell line, KYSE150, contains an amplification of the JMJD2C locus. ChIP-seq was performed using chromatin from control or JMJD2C-depleted KYSE150 cells and antibodies recognizing JMJD2C, H3K4me3, H3K9me3 or H3K36me3.
https://www.omicsdi.org/dataset/arrayexpress-repository/E-GEOD-53938
Esophageal Neoplasms; Cancer of Esophagus; Esophageal CancerEsophageal Neoplasms; Cancer of Esophagus; Esophageal Cancer
Esophageal Neoplasms; Cancer of Esophagus; Esophageal Cancer. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms and diseases is provided.
https://lookfordiagnosis.com/mesh_info.php?term=Esophageal+Neoplasms&lang=1
Keywords: esophageal neoplasm | barasertib Mediated Aurora Kinase B InhibitionKeywords: esophageal neoplasm | barasertib Mediated Aurora Kinase B Inhibition
p?=?0.035). 35 (60.3%) and 18 sufferers (31%) experienced quality 1C2 SNX-2112 or 3C4 toxicity, respectively (CTCAE v4.0). Bottom line: Radiochemotherapy in older sufferers is normally a feasible treatment and its own outcome is normally close to youthful sufferers outcome released in the books. Operative resection, after extensive geriatric assessment, ought to be suggested as the typical treatment for adenocarcinoma of lower esophagus or gastroesophageal junction in older sufferers with great PS and low co-morbidity profile, since it is in youthful sufferers. Keywords: esophageal neoplasm, older sufferers, radiotherapy, chemoradiotherapy, esophagectomy Launch Esophageal cancers (OC) may be the 8th most common cancers world-wide, with 481,000 brand-new situations (3.8% of the full total) approximated in 2008, as well as the sixth most common reason behind loss of life from cancer with 406,000 fatalities (5.4% of the full total) (1). Generally in most traditional western countries, squamous cell ...
http://barasertib.info/tag/keywords-esophageal-neoplasm/
More tests needed for oesophageal cancer patients - Healthcanal.com : Healthcanal.comMore tests needed for oesophageal cancer patients - Healthcanal.com : Healthcanal.com
Dr Sarah Thompson, a surgeon and PhD candidate, says tiny cancer cells are being missed in routine pathology examinations, resulting in half of patients who have been given the all-clear dying within five years.. In a study of 250 oesophageal cancer patients in Adelaide over the past 10 years, Dr Thompson found that of the 119 people given a clean bill of health, only 62 were still alive five years later.. If you tell people they are totally clear of cancer and then a year later they come back with secondary cancer, that is a devastating result, she says.. More than 1000 people are diagnosed with cancer of the oesophagus in Australia each year. There are two types: squamous cell carcinoma, occurring in the top part of the oesophagus; and adenocarcinoma, which is closer to the stomach. The latter has increased by 400% in Australia since the 1970s.. Dr Thompsons study showed that oesophageal tumour cells are being missed in the lymph nodes in conventional pathological tests.. Pathologists ...
https://www.healthcanal.com/cancers/14876-more-tests-needed-for-oesophageal-cancer-patients.html
Jumonji/Arid1b (Jarid1b) protein modulates human esophageal cancer cell growthJumonji/Arid1b (Jarid1b) protein modulates human esophageal cancer cell growth
Esophageal cancer is one of the most lethal human cancers that occur worldwide. It is the eighth most common cancer in several European countries and its incidence is on the increase in Western countries (1-3). Barretts esophagus, the only known precursor to esophageal adenocarcinoma, is prevalent in Western countries (1-3). In Barretts esophagus, a human metaplastic condition is characterized by a posterior intestinal-like phenotype in an anterior organ. Underlying it is a mechanism of epigenetically regulated, developmentally critical genes, such as the HOXB family (4). By contrast, the squamous cell carcinoma of the esophagus is predominant in Asia, including Japan (1-3).. A previous study suggested that the genetic and epigenetic alterations, which constrain tumor suppressor genes and activate oncogenes, are involved in the initiation, progression and development of carcinogenesis in the esophagus, which is asssociated with exposure to environmental carcinogens (5). Specifically, animal ...
https://www.spandidos-publications.com/10.3892/mco.2013.127
STAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells | BMC Cancer | Full TextSTAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells | BMC Cancer | Full Text
Although several molecular alterations were identified, esophageal cancers still represent a major challenge of interdisciplinary oncology [24]. Among of which, STAT3 signaling pathway is particular an important one. STAT3 always play a critical role in oncogenic signaling in the carcinogenesis and progression of several cancers. In normal cells, STAT3 expression and activity is under tight control to ensure physiological cell proliferation, survival, differentiation and motility. For esophageal cancer, constitutively activated STAT3 expression was found in both esophageal squamous cell carcinomas (ESCC) and Barretts adenocarcinomas (BAC) [25]. While, the mechanisms involved in its activation remain to be further identified. Excepts for the potential STAT3 gene amplification on chromosome 17q21, a region frequently amplified in esophageal adenocarcinomas [26], inflammation-associated STAT3 activation is also conceivable, at least in vivo [27]. In this paper, we found another way mediated the ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1303-0
PRAF3 induces apoptosis and inhibits migration and invasion in human esophageal squamous cell carcinoma | BMC Cancer | Full TextPRAF3 induces apoptosis and inhibits migration and invasion in human esophageal squamous cell carcinoma | BMC Cancer | Full Text
Members of the Prenylated Rab acceptor domain family (PRAF) are essential for the regulation of many cellular processes [22, 23]. Here we have demonstrated that PRAF3 could induce apoptosis and inhibit migration and invasion of ESCC cells and hence may serve as a tumor suppressor in ESCC.. Although the role of PRAF3 has been studied in several other tumors using tumor cell lines [7, 9, 10, 24], there is a lack of investigation into the relationship between PRAF3 expression and the clinical features of ESCCs. In the present study, we found that the expression level of PRAF3 mRNA and protein in ESCC tissues was significantly lower than that in the matched normal tissues. In addition, we found that down-regulation of PRAF3 expression was significantly correlated with poorly differentiated grading, advanced tumor stage and lymph node metastasis of ESCC. These results would imply that PRAF3 may play an important role in regulating the progression and metastasis of ESCCs, although further in vivo ...
https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-12-97
THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal...
TY - JOUR. T1 - THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal squamous cell carcinoma cells as revealed by transposon activation mutagenesis. AU - Hayashi, Masato. AU - Kawakubo, Hirofumi. AU - Fukuda, Kazumasa. AU - Mayanagi, Shuhei. AU - Nakamura, Rieko. AU - Suda, Koichi. AU - Hayashida, Testu. AU - Wada, Norihito. AU - Kitagawa, Yuko. PY - 2019/12/1. Y1 - 2019/12/1. N2 - Background: Although chemotherapy is a core treatment for esophageal cancer, some patients develop drug resistance. Gene screening with transposons (i.e. mobile genetic elements) is a novel procedure for identifying chemotherapy-resistant genes. Transposon insertion can randomly affect nearby gene expression. By identifying the affected genes, candidate genes can be found. The present study aimed to identify cisplatin (CDDP)/5-fluorouracil (5-FU)-resistant genes in in vitro human esophageal squamous cell carcinoma with transposons. Methods: After ...
https://keio.pure.elsevier.com/en/publications/thump-domain-containing-2-protein-possibly-induces-resistance-to-
THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal...THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal...
TY - JOUR. T1 - THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal squamous cell carcinoma cells as revealed by transposon activation mutagenesis. AU - Hayashi, Masato. AU - Kawakubo, Hirofumi. AU - Fukuda, Kazumasa. AU - Mayanagi, Shuhei. AU - Nakamura, Rieko. AU - Suda, Koichi. AU - Hayashida, Testu. AU - Wada, Norihito. AU - Kitagawa, Yuko. PY - 2019/12/1. Y1 - 2019/12/1. N2 - Background: Although chemotherapy is a core treatment for esophageal cancer, some patients develop drug resistance. Gene screening with transposons (i.e. mobile genetic elements) is a novel procedure for identifying chemotherapy-resistant genes. Transposon insertion can randomly affect nearby gene expression. By identifying the affected genes, candidate genes can be found. The present study aimed to identify cisplatin (CDDP)/5-fluorouracil (5-FU)-resistant genes in in vitro human esophageal squamous cell carcinoma with transposons. Methods: After ...
https://pure.fujita-hu.ac.jp/en/publications/thump-domain-containing-2-protein-possibly-induces-resistance-to-
Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma. | Profiles RNS
Gupta VK, Park JO, Jaskowiak NT, Mauceri HJ, Seetharam S, Weichselbaum RR, Posner MC. Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma. Ann Surg Oncol. 2002 Jun; 9(5):500-4 ...
https://profiles.uchicago.edu/profiles/display/216017
Esophageal Cancer Patients with Less Lymph Node Dissection May Have Better PrognosisEsophageal Cancer Patients with Less Lymph Node Dissection May Have Better Prognosis
Background: China is a high incidence area of esophageal cancer. Esophageal squamous cell carcinoma recurrence and mortality rates are relatively high. Recent studies show that the recurrence rate remains very high even through the implementation of lymph node expanding dissection. Methods and Results: In order to study the relationship between lymph node dissection number and survival of the patients with esophageal squamous cell carcinoma, 407 cases of esophageal cancer are selected in the First Affiliated Hospital of Xian Jiaotong University from January 2009 to June 2013. There were 15 cases without surgery, while the rest of the 392 patients were post-operation in follow-up. 54 patients were lost in follow-up, and the rate was 13.8%. Finally, there were 338 patients entered into our research. The median age was 58 (37 - 81), males accounted for 79%. The number of lymph node dissection is for a total of 2091, and a median of 5. Positive lymph nodes are 400, while the total positive rate is 19.1%.
https://m.scirp.org/papers/68140
Plus itPlus it
Human esophageal squamous cell carcinoma exhibits a reduced degree of differentiation, as evidenced by the decreased capacity to form cross-linked envelopes, thus suggesting that these tumor cells frequently display a defect in the terminal differentiation pathway (3) . Involucrin is a major component of the cornified envelope and is considered to be an appropriate marker for terminal differentiation. The results described above demonstrate that adenovirus-mediated transfer of the p21sdi1 gene up-regulates involucrin protein expression and induces terminal differentiation in human esophageal squamous cell carcinoma cells, thereby leading to sequential apoptotic cell death.. Adenovirus-mediated gene transfer is a highly efficient gene delivery system. We used a recombinant adenovirus to overexpress p21sdi1 in normal and neoplastic squamous cells. Preliminary titration studies showed that transient transgene expression in most populations of infected cells can be expected at an MOI of 100. In ...
http://clincancerres.aacrjournals.org/content/5/12/4233
Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas<...
TY - JOUR. T1 - Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas. AU - Toh, Y.. AU - Kuwano, H.. AU - Mori, M.. AU - Nicolson, G. L.. AU - Sugimachi, K.. PY - 1999/1/1. Y1 - 1999/1/1. N2 - The MTA1 gene is a recently identified novel candidate breast cancer metastasis-associated gene which has been implicated in the signal transduction or regulation of gene expression. We examined the mRNA expression levels of the MTA1, the human homologue of the rat mta1 gene in 47 surgically resected oesophageal squamous cell carcinomas by quantitative reverse transcription polymerase chain reaction. The relative overexpression of MTA1 mRNA (tumour/normal ratio ≥ 2) was observed in 16 out of 47 (34.0%) oesophageal carcinomas. Oesophageal tumours overexpressing MTA1 mRNA (T/N ratio ≥ 2) showed significantly higher frequencies of adventitial invasion (P , 0.05) and lymph node metastasis (P , 0.05), and tended to have a higher rate of lymphatic involvement than the ...
https://kyushu-u.pure.elsevier.com/en/publications/overexpression-of-metastasis-associated-mta1-mrna-in-invasive-oes
Fra-1 Regulates the Expression of HMGA1, Which is Associated with a Poor Prognosis in Human Esophageal Squamous Cell Carcinoma ...Fra-1 Regulates the Expression of HMGA1, Which is Associated with a Poor Prognosis in Human Esophageal Squamous Cell Carcinoma ...
Background The expression of Fos-related antigen 1 (Fra-1) affects tumor progression, migration, and invasion. In this study, we identified the genes regulated by Fra-1 in esophageal squamous cell...
https://rd.springer.com/article/10.1245/s10434-016-5666-5
Women Health: Women Health: Cancer of Endometrium/Endometrial Cancer Chinese Herbal Treatments - Dong Ling CaoWomen Health: Women Health: Cancer of Endometrium/Endometrial Cancer Chinese Herbal Treatments - Dong Ling Cao
Gong ling Cao is also known as blushred rabdosia. The sweet, bitter and cold herb has been used in TCM to treat chronic bronchitis, chronic inflammation of the pelvic area, swelling of throat, insect bites and snake bites as it clears heat and toxins, nourish yin, remove blood stasis and relieves pain by enhancing the functions of stomach, lung and liver channels. In vitro, researcher found that Gong ling Cao has cytotxicity activity against CaEs-17 human esophageal cancer cell line, at 2 and 3ug/ml, the inhibiting rates were 40% and 75%. Can it be used effective against endometrial cancer? Further studies is needed ...
https://thetruestoriesstories.blogspot.ca/2017/04/women-health-cancer-of_20.html
Cryopreservation - Biology-OnlineCryopreservation - Biology-Online
What should we use as medium for cryopreservation of human esophageal cancer cell line - FBS with 10% DMSO OR its own medium with 10% DMSO ...
https://www.biology-online.org/biology-forum/viewtopic.php?p=140635
Oxaliplatin induces mitotic catastrophe and apoptosis in esophageal cancer cells<...
TY - JOUR. T1 - Oxaliplatin induces mitotic catastrophe and apoptosis in esophageal cancer cells. AU - Ngan, Chew Yee. AU - Yamamoto, Hirofumi. AU - Takagi, Akimitsu. AU - Fujie, Yujiro. AU - Takemasa, Ichiro. AU - Ikeda, Masataka. AU - Takahashi-Yanaga, Fumi. AU - Sasaguri, Toshiyuki. AU - Sekimoto, Mitsugu. AU - Matsuura, Nariaki. AU - Monden, Morito. PY - 2008/1/1. Y1 - 2008/1/1. N2 - The platinum-based chemotherapeutic agent oxaliplatin displays a wide range of antitumor activities. However, the underlying molecular responses to oxaliplatin in esophageal cancer remain largely unknown. In the present study, we investigated the effect of oxaliplatin on two esophageal cancer cell lines, squamous cell carcinoma (TE3) and adenocarcinoma (TE7). Following cell-cycle arrest at G2 phase after oxaliplatin treatment, TE3 cells died via apoptosis and TE7 cells died via mitotic catastrophe. Survivin was inhibited more in TE7 cells compared with TE3 cells, but inhibition of survivin using small ...
https://kyushu-u.pure.elsevier.com/ja/publications/oxaliplatin-induces-mitotic-catastrophe-and-apoptosis-in-esophage
Aberrant methylation of the Ras-related Associated with Diabetes gene in human primary esophageal cancer<...
TY - JOUR. T1 - Aberrant methylation of the Ras-related Associated with Diabetes gene in human primary esophageal cancer. AU - Jin, Zhe. AU - Feng, Xianling. AU - Jian, Qianhe. AU - Cheng, Yulan. AU - Gao, Yan. AU - Zhang, Xiaojing. AU - Wang, Liang. AU - Zhang, Yuan. AU - Huang, Weiling. AU - Fan, Xinmin. AU - Chen, Si. AU - Yu, Huimin. AU - Zhao, Zhenfu. AU - Dong, Ming. AU - Liu, Jie. AU - Mori, Yuriko. AU - Meltzer, Stephen. PY - 2013/11. Y1 - 2013/11. N2 - Background/Aim: Ras-related associated with diabetes (RRAD), a member of the Ras-related GTPase superfamily, is frequently methylated in several human cancers, though its methylation profile remains unclear in esophageal cancer. Materials and Methods: We examined RRAD promoter hypermethylation using real-time quantitative methylation-specific PCR in 229 primary human esophageal tissues of contrasting histological types. Results: RRAD hypermethylation showed highly discriminative receiver-operator characteristic curve profiles, clearly ...
https://jhu.pure.elsevier.com/en/publications/aberrant-methylation-of-the-ras-related-associated-with-diabetes--3
Gefitinib for oesophageal cancer progressing after chemotherapy (COG): A phase 3, multicentre, double-blind, placebo-controlled...
Background: Evidence is scarce for the effectiveness of therapies for oesophageal cancer progressing after chemotherapy, and no randomised trials have been reported. We aimed to compare gefitinib with placebo in previously treated advanced oesophageal cancer. Methods: For this phase 3, parallel, randomised, placebo-controlled trial, eligible patients were adults with advanced oesophageal cancer or type I/II Siewert junctional tumours, histologically confirmed squamous-cell carcinoma or adenocarcinoma, who had progressed after chemotherapy, with WHO performance status 0-2, and with measurable or evaluable disease on CT scan. Participants were recruited from 48 UK centres and randomly assigned (1:1) to gefitinib (500 mg) or matching placebo by simple randomisation with no stratification factors. Patients, clinicians, and trial office staff were masked to treatment allocation. Treatment continued until disease progression, unacceptable toxicity, or patient choice. The primary outcome was overall survival,
https://www.phc.ox.ac.uk/publications/470727
Chloroquine affects autophagy to achieve an anticancer effect in EC109 esophageal carcinoma cells in vitroChloroquine affects autophagy to achieve an anticancer effect in EC109 esophageal carcinoma cells in vitro
Esophageal carcinoma is a malignancy that severely threatens human health, with a high incidence rate and a low 5‑year survival rate. Resistance to chemotherapy frequently emerges during its treatment, partly due to the induction of autophagy. Therefore, targeting autophagy may be a promising therapeutic approach for the treatment of esophageal carcinoma. In the present study, it was investigated how chloroquine (CQ) can influence the growth ability and biological behaviors of EC109 esophageal squamous carcinoma cells in vitro, as well as the potential molecular mechanisms behind its activity. It was demonstrated that CQ could suppress the growth and proliferation of EC109 cells in a time‑ and dose‑dependent manner; migration and colony formation abilities were also inhibited by CQ. Furthermore, subsequent to the exposure to CQ, the number of autophagosomes was clearly increased in EC109 cells overexpressing green fluorescent protein tagged‑light chain (LC)3 when observed by fluorescence ...
https://www.spandidos-publications.com/ol/15/1/1143/abstract
Advanced esophageal cancer patients who receive RT alone experience less problems when swallowing | EurekAlert! Science NewsAdvanced esophageal cancer patients who receive RT alone experience less problems when swallowing | EurekAlert! Science News
Radiation therapy alone is as effective in decreasing swallowing complications experienced by advanced esophageal cancer patients as RT combined with chemotherapy, thus allowing patients to forgo chemotherapy, according to research presented today at the American Society for Radiation Oncologys 56th Annual Meeting.
https://www.eurekalert.org/pub_releases/2014-09/asfr-aec091414.php
Dietary Factors and Esophageal Cancer in the Caspian Littoral of Iran | Cancer ResearchDietary Factors and Esophageal Cancer in the Caspian Littoral of Iran | Cancer Research
A study was undertaken to attempt to relate the distribution of exogenous factors to the varying incidences of esophageal cancer in the Caspian Littoral of Iran. For the study, 38 villages were chosen by random sampling in 14 regions defined by their esophageal cancer incidence and environmental characteristics. Information was obtained on the dietary, social, and cultural features of each village. In addition, an extensive 5-day study of 6 randomly selected households in each of the 38 villages was conducted. The study consisted of measured dietary intake, a historical food consumption questionnaire, and clinical examinations of adult occupants.. Preliminary results show no single factor responsible for the etiology of esophageal cancer. However, there were some major dietary differences between the regions of different esophageal cancer risk. Bread was the chief staple food in high-incidence areas; rice, in low-incidence areas. In high-incidence areas, there was a low intake of vitamins A and ...
http://cancerres.aacrjournals.org/content/35/11_Part_2/3493.long
Understanding The Molecular Diversity of Esophageal Cancer - BUCK Cancer FoundationUnderstanding The Molecular Diversity of Esophageal Cancer - BUCK Cancer Foundation
is key for effective targeted therapies.. by Rosa Moreno-Hanson, PhD. The incidence of esophageal cancer in the USA is markedly demarcated by gender and race. The incidence is greater in men, and the predominance of specific esophageal cancer subtypes differs among Caucasians and African Americans. Two main subtypes of esophageal cancer are recognized based on tissue analysis: esophageal squamous cell carcinoma (ESCC, more common in African Americans), and esophageal adenocarcinoma (EAC, more common in Caucasians). The upper and mid-esophagus are predominantly affected by ESCC1. Consumption of alcohol and use of tobacco are considered major risk factors for developing ESCC. Combined use of alcohol and tobacco is known to further augment the risk for developing ESCC. This is due to the compounding effect of alcohol as an irritant of the esophageal tissue and tobacco as the source of carcinogens2. Currently, EAC represents the predominant subtype in the USA; 80% of all cases of esophageal cancer ...
http://www.buckcancerfoundation.org/blog/2017/4/10/understanding-the-molecular-diversity-of-esophageal-cancer
Esophageal cancer risk by type of alcohol drinking and smoking: a case-control study in Spain | BMC Cancer | Full TextEsophageal cancer risk by type of alcohol drinking and smoking: a case-control study in Spain | BMC Cancer | Full Text
The effect of tobacco smoking and alcohol drinking on esophageal cancer (EC) has never been explored in Spain where black tobacco and wine consumptions are quite prevalent. We estimated the independent effect of different alcoholic beverages and type of tobacco smoking on the risk of EC and its main histological cell type (squamous cell carcinoma) in a hospital-based case-control study in a Mediterranean area of Spain. We only included incident cases with histologically confirmed EC (n = 202). Controls were frequency-matched to cases by age, sex and province (n = 455). Information on risk factors was elicited by trained interviewers using structured questionnaires. Multiple logistic regression was used to estimate adjusted odds ratios and 95% confidence intervals (CI). Alcohol drinking and tobacco smoking were strong and independent risk factors for esophageal cancer. Alcohol was a potent risk factor with a clear dose-response relationship, particularly for esophageal squamous-cell cancer. Compared to
https://0-bmccancer-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2407-8-221
PatientsLikeMe | Benign esophageal tumor symptoms, treatments & patient forums | PatientsLikeMePatientsLikeMe | Benign esophageal tumor symptoms, treatments & patient forums | PatientsLikeMe
Benign esophageal tumor: Find the most comprehensive real-world symptom and treatment data on benign esophageal tumor at PatientsLikeMe. 2 patients with benign esophageal tumor experience fatigue, insomnia, depressed mood, pain, and anxious mood and use Milnacipran and Oxycodone ER to treat their benign esophageal tumor and its symptoms.
https://www.patientslikeme.com/conditions/2167-benign-esophageal-tumor
Plus itPlus it
Purpose: We previously revealed that the calreticulin (CRT) gene is a candidate oncogene promoting cell migration and invasion and that neuropilin-1 (NRP1) is a possible effector downstream of CRT in esophageal squamous carcinoma cells. This study aims to explore the mechanisms underlying the migration and invasion of esophageal cancer cells regulated by CRT through NRP1.. Experimental Design: Quantitative reverse-transcription polymerase chain reaction, Western blot analysis, chromatin immunoprecipitation, and reporter gene assays were used to investigate the relationship between CRT and NRP1. In vitro and in vivo assays were carried out to evaluate the effects of NRP1 on malignant phenotypes of ESCC cells and tumor metastasis in NOD/SCID mice. Immunohistochemistry was performed to analyze the expression of CRT and NRP1 in esophageal squamous cell carcinomas (ESCC).. Results: Knockdown of CRT decreased the expression of NRP1. Inhibition of NRP1 reduced ESCC cell motility in vitro and ...
http://clincancerres.aacrjournals.org/content/early/2014/11/13/1078-0432.CCR-14-0583
Esophageal cancer - WikipediaEsophageal cancer - Wikipedia
Esophageal cancer is cancer arising from the esophagus-the food pipe that runs between the throat and the stomach. Symptoms often include difficulty in swallowing and weight loss. Other symptoms may include pain when swallowing, a hoarse voice, enlarged lymph nodes (glands) around the collarbone, a dry cough, and possibly coughing up or vomiting blood. The two main sub-types of the disease are esophageal squamous-cell carcinoma (often abbreviated to ESCC), which is more common in the developing world, and esophageal adenocarcinoma (EAC), which is more common in the developed world. A number of less common types also occur. Squamous-cell carcinoma arises from the epithelial cells that line the esophagus. Adenocarcinoma arises from glandular cells present in the lower third of the esophagus, often where they have already transformed to intestinal cell type (a condition known as Barretts esophagus). Causes of the squamous-cell type include tobacco, alcohol, very hot drinks, poor diet, and ...
https://en.wikipedia.org/wiki/Esophageal_cancer
UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185
1. Yang J, Liu X, Cao S, Dong X, Rao S, Cai K. Understanding Esophageal Cancer: The Challenges and Opportunities for the Next Decade. Front Oncol. 2020;10:1727 2. Thrift AP. Global burden and epidemiology of Barrett oesophagus and oesophageal cancer. Nat Rev Gastroenterol Hepatol. 2021 3. Then EO, Lopez M, Saleem S, Gayam V, Sunkara T, Culliford A. et al. Esophageal Cancer: An Updated Surveillance Epidemiology and End Results Database Analysis. World J Oncol. 2020;11:55-64 4. Demarest CT, Chang AC. The Landmark Series: Multimodal Therapy for Esophageal Cancer. Ann Surg Oncol. 2021 5. Reichenbach ZW, Murray MG, Saxena R, Farkas D, Karassik EG, Klochkova A. et al. Clinical and translational advances in esophageal squamous cell carcinoma. Adv Cancer Res. 2019;144:95-135 6. Li Y, Li Y, Chen X. NOTCH and Esophageal Squamous Cell Carcinoma. Adv Exp Med Biol. 2021;1287:59-68 7. Christopoulos PF, Gjolberg TT, Kruger S, Haraldsen G, Andersen JT, Sundlisaeter E. Targeting the Notch Signaling Pathway in ...
https://www.ijbs.com/v17p3024.htm
Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of...Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of...
To assess the relative risk of esophageal cancer associated with osteoporosis study drugs (alendronate, etidronate, ibandronate, risedronate, and raloxifene), initiators of osteoporosis drugs and non-initiators (comparators, women sharing match criteria with the initiator) entered an inception cohort for every three-month period, beginning in the first quarter of 1996. Assignment to study drug exposure group remained fixed from the start of follow-up, analogous to an intent-to-treat analysis. The risk of esophageal cancer among initiators of study drug compared to non-initiators of study drug was estimated through calculation of a hazard ratio. For calculation of 721+ day hazard ratios, only esophageal cancer cases occurring at least 721 days from initiation of study drug were used. For calculation of 1441+ day hazard ratios, only esophageal cancer cases occurring at least 1441 days from initiation of study drug were used ...
https://clinicaltrials.gov/ct2/show/NCT01077817
Guest blog: Dr. Shaheen weighs in on esophageal cancer awareness and prevention | EndoscopyGuest blog: Dr. Shaheen weighs in on esophageal cancer awareness and prevention | Endoscopy
Esophageal cancer is a devastating, but potentially preventable, disease. The catch is that by the time that symptoms occur, the cancer has often progressed too far to allow cure.. So what is a person to do who would like to avoid this cancer? The best thing is to know the risk factors. Longterm heartburn is a strong risk factor. Smoking, male gender, and obesity also figure into your risk for this disease. If you have two or more of these risk factors, have a conversation with your primary care doctor. You may need a screening upper endoscopy - a simple test where we put a light tube with a camera down your esophagus (or food tube) to make sure that you dont have a precancerous or cancerous changes in your esophagus.. So ask your doctor. A few minutes could literally save a life.. Dr. Shaheen is a paid consultant to Cook Medical regarding the research and development of medical devices.. ...
https://www.cookmedical.com/endoscopy/guest-blog-dr-shaheen-weighs-in-on-esophageal-cancer-awareness-and-prevention/
Risk factors for oesophageal squamous dysplasia in adult inhabitants of a high risk region of China | GutRisk factors for oesophageal squamous dysplasia in adult inhabitants of a high risk region of China | Gut
Background: Oesophageal squamous cell carcinoma (OSCC) is a common cancer worldwide and has a very high mortality rate. Squamous dysplasia is the precursor lesion for OSCC and it can be seen during routine endoscopy with Lugols iodine staining. We aimed to examine the risk factors for squamous dysplasia and determine if a risk model could be constructed which would be useful in selecting apparently healthy subjects for endoscopic screening in a high risk population in Linzhou, Peoples Republic of China.. Subjects and methods: In this cross sectional study, 724 adult volunteers aged 40-65 years were enrolled. All subjects completed a questionnaire regarding potential environmental exposures, received physical and dental examinations, and underwent upper endoscopy with Lugols iodine staining and biopsy. Subjects were categorised as having or not having histologically proven squamous dysplasia/early cancer. Risk factors for dysplasia were examined using univariate and multivariate logistic ...
https://gut.bmj.com/content/54/6/759.abstract
Expression and up-regulation of interleukin-6 in oesophageal carcinoma cells by n-sodium butyrate<...
TY - JOUR. T1 - Expression and up-regulation of interleukin-6 in oesophageal carcinoma cells by n-sodium butyrate. AU - Wang, L. S.. AU - Chow, K. C.. AU - Wu, C. W.. PY - 1999. Y1 - 1999. N2 - Recently, the serum level of interleukin (IL)-6 has been shown to correlate with disease progression and prognosis of cancer patients. However, the available information about the source and the pathophysiological regulation of IL-6 in cancer cells is limited. Thus, in this study, we tried to identify the source and the clinical roles of serum IL-6 in patients with cesophageal squamous cell carcinoma (ESCC), and then further to characterize the biological regulation of IL-6 in ESCC cell lines. Sera and tissue specimens from 80 consecutive patients with ESCC were collected between 1993 and 1997. Additionally, three ESCC cell lines were used for in vitro study. The concentration of serum IL-6 was measured by enzyme-linked immunosorbent assay (ELISA), and correlated the survival time with measured IL-6 ...
https://tmu.pure.elsevier.com/en/publications/expression-and-up-regulation-of-interleukin-6-in-oesophageal-carc
Correlation analysis between polymorphism of GSTP1, XPD and XRCC1 gene in esophageal carcinoma patients and treatment...Correlation analysis between polymorphism of GSTP1, XPD and XRCC1 gene in esophageal carcinoma patients and treatment...
Objective: As a common malignant tumor, esophageal carcinoma lacked specific clinical symptoms, leading to distal metastasis at terminal stage. Cispla..
https://www.alliedacademies.org/abstract/correlation-analysis-between-polymorphism-of-gstp1-xpd-and-xrcc1-gene-in-esophageal-carcinoma-patients-and-treatment-efficiency-of-9666.html
Leukotriene receptor expression in esophageal squamous cell cancer and non-transformed esophageal epithelium: a matched case...Leukotriene receptor expression in esophageal squamous cell cancer and non-transformed esophageal epithelium: a matched case...
Leukotriene B4 (LTB4R and LTB4R2) and cysteinyl leukotriene receptors (CYSLTR1 and CYSLTR2) contribute to malignant cell transformation. We aimed to investigate the expression of LTB4R, LTB4R2, CYSLTR1 and CYSLTR2 in esophageal squamous cell carcinoma and adjacent non-transformed squamous epithelium of the esophagus, as well as in control biopsy samples from esophageal squamous epithelium of patients with functional dyspepsia. Expression of LTB4R, LTB4R2, CYSLTR1 and CYSLTR2 was analyzed by immunohistochemistry (IHC) and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) in biopsy samples of 19 patients with esophageal squamous cell cancer and 9 sex- and age-matched patients with functional dyspepsia. LTB4R, LTB4R2, CYSLTR1 and CYSLTR2 were expressed in all biopsy samples. Major findings were: 1) protein levels of all leukotriene receptors were significantly increased in esophageal squamous cell cancer compared to control mucosa (p | 0.05); 2) CYSLTR1 and CYSLTR2 gene expression was
https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-016-0499-z/figures/2
北京大学医学部机构知识库([email protected]): Detection of human papillomavirus in Chinese esophageal squamous cell carcinoma and its adjacent...
AIM: To investigate the putative role of human papillomavirus (HPV) infection in the carcinogenesis of esophageal squamous cell carcinoma in China.. METHODS: Twenty-three esophageal squamous cell carcinoma samples and the distal normal epithelium from Shanxi Province, and 25 more esophageal squamous cell carcinoma samples from Anyang city, two areas with a high incidence of esophageal cancer in China, were detected for the existence of HPV-16 DNA by PCR, mRNA in situ hybridization (ISH) and immunohistochemistry (IHC) targeting HPV-16 E6 gene.. RESULTS: There were approximately 64% (31/48) patients having HPV-16 DNA in tumor samples, among them nearly two-thirds (19/31) samples were detected with mRNA expression of HPV-16 E6. However, in the normal esophageal epithelium from cancer patients, the DNA and mRNA of HPV-16 were found with much less rate: 34.7% (8/23) and 26.1% (6/23) respectively. In addition, at protein level detected by IHC assay, 27.1% (13/48) tumor samples had virus oncoprotein E6 ...
http://ir.bjmu.edu.cn/handle/400002259/66782
Esophageal squamous cell carcinoma (ESCC) and esophagogastric junction adenocarcinoma (EGJA) will - The Role of PPAR Activation...Esophageal squamous cell carcinoma (ESCC) and esophagogastric junction adenocarcinoma (EGJA) will - The Role of PPAR Activation...
Esophageal squamous cell carcinoma (ESCC) and esophagogastric junction adenocarcinoma (EGJA) will be the two primary types of gastrointestinal cancers that pose an enormous threat to individual health. tumor-linked autoantibody biomarkers in esophageal squamous cellular carcinoma reported in several research. Mmp-7: Matrix metallopeptidase 7; Hsp70: Heat shock proteins 70; PRDX 6: Peroxiredoxin 6; Bmi-1: BMI1 proto-oncogene, polycomb band finger; FG-4592 supplier Koc: Insulin-like growth aspect 2 mRNA binding proteins 3; C-Myc: MYC proto-oncogene, bHLH transcription aspect; IMP1: Insulin-like development aspect 2 mRNA binding proteins 1. The many comprehensively investigated TA autoantibodies in ESCC have already been p53 autoantibodies accompanied by autoantibodies against P16 and c-Myc. Provided the prominent feature of p53 in cancers it isnt unexpected that may be the most broadly studied autoantibody in ESCC. Autoantibodies against p53 in the medical diagnosis of ESCC have already been ...
http://www.thebiotechdictionary.com/2019/12/22/esophageal-squamous-cell-carcinoma-escc-and-esophagogastric-junction-adenocarcinoma-egja-will/
Superficial Esophageal Neoplasm Pathology Diagnosis And Therapy PDF Book - Mediafile SharingSuperficial Esophageal Neoplasm Pathology Diagnosis And Therapy PDF Book - Mediafile Sharing
Download And Read Superficial Esophageal Neoplasm Pathology Diagnosis And Therapy The River Pirates Longarm And The Branded Beauty Long To Remember Long Work Short
http://dissonant.ca/file-ready/superficial-esophageal-neoplasm-pathology-diagnosis-and-therapy
The cause of Esophageal Squamous Cell Carcinoma is mainly relates to Genomic-wide (3 Joint) . Although Micro-RNA may have...The cause of Esophageal Squamous Cell Carcinoma is mainly relates to Genomic-wide (3 Joint) . Although Micro-RNA may have...
Subject：Biomedical Cancer study Question：The search for genomic-wide, micro-RNA and epigenetics interactions in Esophageal Squamous Cell Carcinoma. Thesis statement (Main idea of literature review): The cause of Esophageal Squamous Cell Carcinoma is mainly relates to Genomic-wide (3 Joint) .. Although Micro-RNA may have influences on it, the surveys on it are lack of reasonable control (quantities, same living environment and habitat), and there is no enough evidence shows Micro RNA can cause it directly.. The environment can raise the risk of ESCC ( Epi-genetics) , especially diet.. For a custom paper on the above, place your Order Now!!. What We Offer: ...
https://www.essaylions.com/the-cause-of-esophageal-squamous-cell-carcinoma-is-mainly-relates-to-genomic-wide-3-joint-although-micro-rna-may-have-influences-on-it-the-surveys-on-it-are-lack-of-reasonable-control-quantitie/
Left Transthoracic Esophagectomy (Ellis) | Adult Chest Surgery, 2e | AccessSurgery | McGraw-Hill MedicalLeft Transthoracic Esophagectomy (Ellis) | Adult Chest Surgery, 2e | AccessSurgery | McGraw-Hill Medical
The advantage of left transthoracic esophagectomy is readily apparent in that it affords a surgical resection with a single incision. In addition to the obvious advantage of decreasing the patients discomfort, the left transthoracic esophagectomy also can be performed in much less time than the Ivor Lewis or McKeown esophagectomy, with operative time averaging 2 to 3 hours.6 The left transthoracic approach does have a number of disadvantages that should be noted. First, although the division of the diaphragm provides excellent visualization of the left upper quadrant of the abdomen via the left chest, the remainder of the abdomen cannot be accessed using this approach. As a result of the limited abdominal exposure, adequate dissection of the pylorus cannot be achieved to perform pyloromyotomy. Many surgeons profess that gastric drainage is an essential component of esophageal reconstruction with gastric conduit placement after esophagectomy and identify the inability to perform a drainage ...
http://accesssurgery.mhmedical.com/content.aspx?bookid=1317§ionid=72427720
SREBP2 is upregulated in esophageal squamous cell carcinoma and co‑operates with c‑Myc to regulate HMGCR expression
Dysregulations of the mevalonate pathway (MVA) have been previously identified. Our previous study demonstrated that 3‑hydroxy‑3‑methylglutaryl‑coenzyme A reductase (HMGCR), the rate‑limiting enzyme of the MVA pathway, was upregulated in esophageal squamous cell carcinoma (ESCC) and statin‑inhibited ESCC tumorigenesis. However, the underlying mechanism of HMGCR regulation in ESCC remains unknown. In the present study, western blotting and immunohistochemistry analysis demonstrated that sterol regulatory element‑binding protein 2 (SREBP2), the master regulator for HMGCR, was upregulated in ESCC clinical samples. Overexpression of SREBP2 expression in ESCC cell lines promoted the growth, migration and colony formation of cancer cells in the MTT, Boyden chamber and soft agar assays, respectively, which was inhibited by lovastatin. Downregulation of SREBP2 expression in ESCC cell lines inhibited the viability, and migration and colony formation abilities of cancer cells. Assessment of ...
https://tessera.spandidos-publications.com/mmr/20/4/3003/abstract
Germline BRCA2 Truncating Mutation in Familial Esophageal Squamous Cell Carcinoma: A Case Controlled Study in China - Article...Germline BRCA2 Truncating Mutation in Familial Esophageal Squamous Cell Carcinoma: A Case Controlled Study in China - Article...
BACKGROUND:Germline mutations of BRCA2 have been reported in various malignancies. We investigated BRCA2 germline mutations in familial clusters with esophageal squamous cell carcinoma (ESCC). MATERIAL AND METHODS:We screened the DNA of familial ESCC patients for BRCA2 germline mutations with whole gene sequencing. Multiple BRCA2 mutations including one novel splice variant, c.426-2A|G were identified. Other family members, sporadic ESCC patients, and controls were also assessed for the novel mutation. RESULTS:The mutation c.426-2A|G was found in 2 affected ESCC sisters and 7 other family members. The splice variant mutation results in exon 5 skipping with a frame shift leading to a premature stop codon in exon 6 and truncation. Novel mutation tracking ruled out single nucleotide polymorphism (SNP) in 100 chromosomes of healthy individuals. CONCLUSIONS:BRCA2 germline mutation in ESCC patients may play a role in genetic susceptibility to familial ESCC. Genetic analysis of BRCA2 in patients with familial
https://www.medscimonit.com/abstract/index/idArt/923926
Selleck Chemicals Blog-Omipalisib Inhibits Esophageal Squamous Cell Carcinoma Growth Through Inactivation of Phosphoinositide 3...Selleck Chemicals Blog-Omipalisib Inhibits Esophageal Squamous Cell Carcinoma Growth Through Inactivation of Phosphoinositide 3...
BACKGROUND Esophageal squamous cell carcinoma (ESCC) is a life-threatening digestive tract malignancy with no known curative treatment. This study aimed to investigate the antineoplastic effects of omipalisib and its underlying molecular mechanisms in ESCC using a high throughput screen. MATERIAL AND METHODS MTT assay and clone formation were used to determine cell viability and proliferation. Flow cytometry was conducted to detect cell cycle distribution and apoptosis. Global gene expression and mRNA expression levels were determined by RNA sequencing and real-time PCR, respectively. Protein expression was evaluated in the 4 ESCC cell lines by Western blot analysis. Finally, a xenograft nude mouse model was used to evaluate the effect of omipalisib on tumor growth in vivo. RESULTS In the pilot screening of a 1404-compound library, we demonstrated that omipalisib markedly inhibited cell proliferation in a panel of ESCC cell lines. Mechanistically, omipalisib induced G₀/G₁ cell cycle arrest ...
https://www.selleckchem.com/blog/Omipalisib-Inhibits-Esophageal-Squamous-Cell-Carcinoma-Growth-Through-Inactivation-of-Phosphoinositide-3-Kinase-PI3K-AKT-Mammalian-Target-of-Rapamycin-mTOR-and-ERK-Signaling.html?pathway=logical_autophagy
Clinicopathological and prognostic values of PD-L1 expression in oesophageal squamous cell carcinoma: a meta-analysis of 31...Clinicopathological and prognostic values of PD-L1 expression in oesophageal squamous cell carcinoma: a meta-analysis of 31...
Several immune checkpoint inhibitors targeting programmed death ligand 1 (PD-L1)/programmed death 1 have successfully improved the prognosis of oesophageal squamous cell carcinoma (ESCC) with approval in certain countries. However, whether the expression of PD-L1 is associated with the degree of benefit is unclear yet and a unified standard of antibody and cut-off value of PD-L1 detection is also lacking. The current meta-analysis then aimed to explore the association between PD-L1 expression and clinicopathological features as well as prognosis in ESCC.. A systematic search on PubMed, Embase, Cochrane Library and Web of Science databases was performed up to 30 March 2021. The correlation between PD-L1 expression and clinicopathological features, as well as prognosis in ESCC, was estimated with the random-effects model.. A total of 5368 patients from 31 retrospective studies were enrolled. The overexpression of PD-L1 was significantly associated with lymph node metastasis (OR 1.342, 95% CI 0.995 ...
https://pmj.bmj.com/content/early/2021/09/09/postgradmedj-2021-140029.full
The Aetiological Role of Human Papillomavirus in Oesophageal Squamous Cell Carcinoma: A Meta-AnalysisThe Aetiological Role of Human Papillomavirus in Oesophageal Squamous Cell Carcinoma: A Meta-Analysis
Background The aetiological role of human papillomavirus (HPV) in oesophageal squamous cell carcinoma (OSCC) has been widely researched for more than three decades, with conflicting findings. In the absence of a large, adequately powered single case-control study, a meta-analysis of all available case-control studies is the most rigorous way of identifying any potential association between HPV and OSCC. We present the first global meta-analysis of case-control studies investigating the role of HPV in OSCC. Methods Case-control studies investigating OSCC tissue for presence of HPV DNA were identified. 21 case-control studies analyzing a total of 1223 cases and 1415 controls, met our inclusion criteria. HPV detection rates were tabulated for each study and all studies were assessed for quality. The random effects method was used to pool the odds ratios (OR). Results From all OSCC specimens included in this meta-analysis, 35% (426/1223) were positive for HPV DNA. The pooled OR for an HPV-OSCC association
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069238
Cytokine Networks In Esophageal Squamous Cell Carcinoma by Tatiana KarakashevaCytokine Networks In Esophageal Squamous Cell Carcinoma by Tatiana Karakasheva
Esophageal cancer is one of the top reasons for cancer-related deaths worldwide, and esophageal squamous cell carcinoma (ESCC) accounts for up to 90% of all esophageal cancer cases. One of the major reasons for the high mortality rate is the lack of targeted therapies for ESCC, particularly for advanced stage disease. The tumor microenvironment (TME) is a complex system of multiple cell types (fibroblasts, immune cells, blood and lymphatic vessels, etc.) that supports tumor growth in various ways. We aimed to investigate some of the mechanisms of dynamic interaction between tumor cells and TME components and to identify approaches to targeting these interactions therapeutically. Desmoplasia, or deposition of connective tissue components (fibroblasts and extracellular matrix (ECM)), is a pronounced histological feature of ESCC. Previous research from the Rustgi lab and others has underscored the importance of cancer-associated fibroblasts (CAFs) and ECM components for ESCC progression. We have identified
https://repository.upenn.edu/edissertations/2378/
MicroRNA Polymorphisms and Environmental Smoke Exposure as Risk Factors for Oesophageal Squamous Cell Carcinoma - pdf descargar
MicroRNA Polymorphisms and Environmental Smoke Exposure as Risk Factors for Oesophageal Squamous Cell Carcinoma. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
http://libros.duhnnae.com/2017/jun8/149830935398-MicroRNA-Polymorphisms-and-Environmental-Smoke-Exposure-as-Risk-Factors-for-Oesophageal-Squamous-Cell-Carcinoma.php
Management of esophageal squamous cell carcinoma with definitive chemoradiotherapy in a patient with scleroderma: Case report...Management of esophageal squamous cell carcinoma with definitive chemoradiotherapy in a patient with scleroderma: Case report...
TY - JOUR. T1 - Management of esophageal squamous cell carcinoma with definitive chemoradiotherapy in a patient with scleroderma. T2 - Case report and review of the literature. AU - Horowitz, David P.. AU - Halmos, Balazs. AU - Poneros, John. AU - Sonett, Joshua. AU - Remotti, Helen. AU - Burri, Ryan J.. PY - 2012/9/1. Y1 - 2012/9/1. UR - http://www.scopus.com/inward/record.url?scp=84887401191&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84887401191&partnerID=8YFLogxK. U2 - 10.1007/s12029-012-9393-2. DO - 10.1007/s12029-012-9393-2. M3 - Review article. C2 - 22585471. AN - SCOPUS:84887401191. VL - 43. SP - S156-S160. JO - Journal of Gastrointestinal Cancer. JF - Journal of Gastrointestinal Cancer. SN - 1941-6628. IS - SUPPL. 1. ER - ...
https://einstein.pure.elsevier.com/en/publications/management-of-esophageal-squamous-cell-carcinoma-with-definitive-
SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis | Journal of...SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis | Journal of...
Solute carrier family 7 member 11(SLC7A11) is a component of cysteine/glutamate transporter, which plays a key role in tumor growth; however, its underlying effect on radiosensitivity in esophageal squamous cell carcinoma (ESCC) remains unclear. This study aimed to clarify SLC7A11s expression and correlation with nuclear expression of nuclear factor erythroid-2 (NRF2)-associated radioresistance in ESCC. We included 127 ESCC patients who received radical chemoradiotherapy. Immunohistochemical staining was used to detect SLC7A11 and NRF2 nuclear expression, and the relationship between clinicopathological characteristics and survival rates or therapy response were evaluated. Western blot, dual-reporter assays and Chromatin immunoprecipitation (ChIP)-sequencing were used to analyze their relationship in vitro. Their roles in radioresistance were then investigated through multiple validation steps. NRF2 nuclear expression and SLC7A11 expression were overexpressed in ESCC tissues and were positively
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-03042-7
Downregulation of microRNA-21 inhibited radiation-resistance of esophageal squamous cell carcinoma | Cancer Cell International ...Downregulation of microRNA-21 inhibited radiation-resistance of esophageal squamous cell carcinoma | Cancer Cell International ...
MicroRNA-21 (miR-21) was previously reported being dysregulated in many kinds of cancer including esophageal squamous cell carcinoma (ESCC). In the present study, we aimed to investigate the role of miR-21 in ESCC, especially in its effects on radiation-sensitivity of ESCC. Expression of miR-21 was detected in 63 pairs ESCC tumor and adjacent non-tumoral tissues using qRT-PCR, correlation between miR-21 and clinicopathological feature of ESCC was analyzed. The role of miR-21 in the proliferation, cell cycle and apoptosis of ESCC cells during irradiation were studied. MicroRNA-21 expression was significantly increased in ESCC tumor tissues. Expression of miR-21 was positively associated with advanced clinical stage. Under irradiation, overexpression of miR-21 increased cell proliferation and cells in S phase, and inhibited cell apoptosis of ESCC cells. In contrast, knockdown of miR-21 had an opposite effect. Downregulation of miR-21 inhibited the radiation-resistance of ESCC, whereas overexpression of
https://cancerci.biomedcentral.com/articles/10.1186/s12935-018-0502-6/figures/6
Esophagus Cancer Survival RateEsophagus Cancer Survival Rate
Esophagus cancer survival rate is now improving due to advanced technology. This does not only refer to the equipment, machine or drugs used to cure esophagus cancer. This also includes commercial media as great sources of finding treatments. There is already the Internet to get information about esophagus cancer and
https://www.cancersurvivalrate.net/esophagus-cancer-survival-rate/
Nutrients | Free Full-Text | Is Early Enteral Nutrition Better for Postoperative Course in Esophageal Cancer Patients? | HTMLNutrients | Free Full-Text | Is Early Enteral Nutrition Better for Postoperative Course in Esophageal Cancer Patients? | HTML
We retrospectively examined esophageal cancer patients who received enteral nutrition (EN) to clarify the validity of early EN compared with delayed EN. A total of 103 patients who underwent transthoracic esophagectomy with three-field lymphadenectomy for esophageal cancer were entered. Patients were divided into two groups; Group E received EN within postoperative day 3, and Group L received EN after postoperative day 3. The clinical factors such as days for first fecal passage, the dose of postoperative albumin infusion, differences of serum albumin value between pre- and postoperation, duration of systematic inflammatory response syndrome (SIRS), incidence of postoperative infectious complication, and use of total parenteral nutrition (TPN) were compared between the groups. The statistical analyses were performed using Mann-Whitney U test and Chi square test. The statistical significance was defined as p < 0.05. Group E showed fewer days for the first fecal passage (p < 0.01), lesser dose of
http://www.mdpi.com/2072-6643/5/9/3461/htm
Molecular basis of Barretts oesophagus and oesophageal adenocarcinoma | GutMolecular basis of Barretts oesophagus and oesophageal adenocarcinoma | Gut
The role of environmental factors is evident from the short time period over which the incidence of Barretts oesophagus6 and oesophageal adenocarcinoma7 has increased. Furthermore, the demonstration of a birth cohort effect, with higher incidence rates in younger cohorts,8 would support the idea that exposure to environmental factors in early life is an important determinant of risk. Identification of specific environmental exposures is difficult, but factors that increase gastro-oesophageal reflux, such as dietary components, increasing body mass index and eradication of Helicobacterpylori, may be relevant.9 Whether or not smoking and alcohol consumption are risk factors for Barretts oesophagus is controversial; however, an association was found in a recent population study.10 In order for an individual to develop Barretts oesophagus, and in some cases oesophageal adenocarcinoma, these environmental exposures probably need to interact with genetically determined characteristics that define ...
http://gut.bmj.com/content/55/12/1810
Search Results | JNCCNSearch Results | JNCCN
Approximately 38,000 new patients will be diagnosed with gastroesophageal cancer in 2008.1 Although this number may be trivial compared with more common cancers, the incidence of esophageal and gastroesophageal junction adenocarcinoma has been steadily climbing over the past 20 years (www.cancer.org; accessed June 10, 2008). Although obesity, gastroesophageal reflux, and Barretts metaplasia may contribute some or great extent to this alarming increase, some of the reasons for this increase remain elusive.2 The global health burden imposed by gastroesophageal cancer parallels that imposed by lung cancer, with approximately 1.4 million new cases and 1.1 million deaths per year.3 Furthermore, the mortality is likely to remain high because early detection of gastroesophageal cancer is not commonly practiced in most countries. Nevertheless, we have witnessed some definite progress in staging and therapy of patients with gastroesophageal cancer. For localized gastroesophageal cancer, progress has ...
https://jnccn.org/search?access=user&f_0=author&q_0=Jaffer+A.+Ajani
Effects of ghrelin administration during chemotherapy with advanced esophageal cancer patients - Hiura - 2012 - Cancer - Wiley...Effects of ghrelin administration during chemotherapy with advanced esophageal cancer patients - Hiura - 2012 - Cancer - Wiley...
Hiura, Y., Takiguchi, S., Yamamoto, K., Takahashi, T., Kurokawa, Y., Yamasaki, M., Nakajima, K., Miyata, H., Fujiwara, Y., Mori, M., Kangawa, K. and Doki, Y. (2012), Effects of ghrelin administration during chemotherapy with advanced esophageal cancer patients. Cancer, 118: 4785-4794. doi: 10.1002/cncr.27430 ...
http://onlinelibrary.wiley.com/doi/10.1002/cncr.27430/references?globalMessage=0
Bergen Open Research Archive: Metabolic risk factors for esophageal squamous cell carcinoma and adenocarcinoma: a prospective...Bergen Open Research Archive: Metabolic risk factors for esophageal squamous cell carcinoma and adenocarcinoma: a prospective...
Background: Obesity is associated with an increased risk of esophageal adenocarcinoma (EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However, little is known about the risk of EAC and ESCC related to other metabolic risk factors. We aimed to examine the risk of EAC and ESCC in relation to metabolic risk factors, separately and combined in a prospective cohort study. Methods: The Metabolic Syndrome and Cancer cohort includes prospective cohorts in Austria, Norway and Sweden, with blood pressure, lipids, glucose and BMI available from 578 700 individuals. Relative risk (RR) for EAC and ESCC was calculated using Coxs proportional hazards analysis for metabolic risk factors categorized into quintiles and transformed into z-scores. The standardized sum of all z-scores was used as a composite score for the metabolic syndrome (MetS). Results: In total, 324 histologically verified cases of esophageal cancer were identified (114 EAC, 184 ESCC and 26 with other histology). BMI ...
https://bora.uib.no/bora-xmlui/handle/1956/9301?locale-attribute=no
Overexpression of IFITM3 predicts the high risk of lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma...Overexpression of IFITM3 predicts the high risk of lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma...
Background. Recent studies have shown that the aberrant expression of IFITM3 is implicated in the lymph node metastasis of many malignancies. Our research aimed to investigate the expression of IFITM3 in pathological N0 (pN0) esophageal squamous cell carcinoma (ESCC) and its relationship with lymph node metastatic recurrence.Methods. Immunohistochemistry (IHC) was used to examine the expression profile of IFITM3 in 104 pairs of samples. Each pair consisted of ESCC tissue and its adjacent normal mucosa (ANM). This aberrant expression was verified by reverse transcription-polymerase chain reaction (RT-PCR) with 20 tumor specimens with strong immunostaining and their mucosal tissues. In addition, 20 samples of low expression tissues and their ANMs were evaluated. Moreover, the correlations between the IFITM3 expression level and the clinicopathological variables, recurrence risk and overall survival (OS) of patients were analyzed.Results. Both IHC and RT-PCR demonstrated that the IFITM3 expression level
https://peerj.com/articles/1355/
Aging | Proteome and phosphoproteome reveal mechanisms of action of atorvastatin against esophageal squamous cell carcinoma -...
Statins comprise a class of prescription drugs used for reducing cholesterol. Evidence has also showed that statins could reduce cancer incidence. However, the anti-tumor mechanism of statins has not been fully defined. Here, we found that atorvastatin inhibited proliferation of esophageal squamous cell carcinoma (ESCC) cells. The underlying mechanisms were explored by mass spectrometry. The proteome data revealed that atorvastatin inhibited the cAMP and Rap1 signal pathways, except for Ras signal pathway. Interestingly, phosphoproteome profiles suggested that ERKT185/Y187, CDK1T14, and BRAC1S1189 phosphorylation–mediated Th17 cell differentiation, Gap junction and the Platinum drug resistance pathway were down-regulated after atorvastatin treatment. The phosphorylation levels of ERKT185/Y187, CDK1T14 and BRAC1S1189 were confirmed by western blotting in KYSE150 cells. More importantly, atorvastatin suppresses ESCC tumor growth in
https://www.aging-us.com/figure/102402/f6
Preoperative serum lipids as prognostic predictors in esophageal squamous cell carcinoma patients with esophagectomy |...Preoperative serum lipids as prognostic predictors in esophageal squamous cell carcinoma patients with esophagectomy |...
https://doi.org/10.18632/oncotarget.15651 Pengxiang Chen, Lihui Han, Cong Wang, Yibin Jia, Qingxu Song, Jianbo Wang, Shanghui Guan, Bingxu Tan, Bowen Liu, Wenqiao Jia, Jianfeng Cui, Wei Zhou, Yufeng...
https://www.oncotarget.com/article/15651/text/
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Digestive System Neoplasms - Full...Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Digestive System Neoplasms - Full...
Dr. Bin Wang developed the investigational vaccine used in this clinical trial and designed the trial protocol.For patients with advanced esophageal squamous carcinoma, gastric adenocarcinoma, pancreatic adenocarcinoma and colorectal adenocarcinoma tumor who have disease progression with first line chemotherapy. Single or multiple doses of personalized mRNA tumor vaccine encoding neoantigen will be given to observe the safety and efficacy the mRNA tumor vaccine.. Primary objectives:. Determine the safety, tolerability and cytokinetics of the personalized mRNA tumor vaccine in patients with advanced esophageal squamous carcinoma, gastric adenocarcinoma, pancreatic adenocarcinoma and colorectal adenocarcinoma.. Secondary objectives:. Make a preliminary evaluation on the efficacy of personalized mRNA tumor vaccine in patients with advanced esophageal squamous carcinoma, gastric adenocarcinoma, pancreatic adenocarcinoma and colorectal adenocarcinoma with the following parameters:. Time of tumor ...
https://clinicaltrials.gov/show/NCT03468244
سامانه دانش گستر بركت - حوزه سلامت. Candidate Gene Association Study of Esophageal Squamous Cell Carcinoma in a High-Risk...
Abstract: There is a region with a high risk for esophageal squamous cell carcinoma (ESCC) in the northeast of Iran. Previous studies suggest that hereditary factors play a role in the high incidence of cancer in the region. We selected 22 functional variants (and 130 related tagSNPs) from 15 genes that have been associated previously with the risk of ESCC. We genotyped a primary set of samples from 451 Turkmens (197 cases and 254 controls). Seven of 152 variants were associated with ESCC at the P = 0.05 level; these single nucleotide polymorphisms were then studied in a validation set of 549 cases and 1,119 controls, which included both Turkmens and non-Turkmens. The association observed for a functional variant in ADH1B was confirmed in the validation set, and that of a tagSNP in MGMT, the association was borderline significant in the validation set, after correcting for multiple testing. The other 5 variants that were associated in the primary set were not significantly associated in the ...
http://health.barakatkns.com/article/222764/candidate-gene-association-study-of-esophageal-squamous-cell-carcinoma-in-a-high-risk-region-in-iran
Esophageal Cancer - Digestive Diseases Center
Esophageal cancer is cancer that occurs in the esophagus, the long, hollow tube that runs from your throat to your stomach. Your esophagus carries food you swallow to your stomach to be digested. Esophageal cancer begins in the cells that line the inside of the esophagus and can occur anywhere in the esophagus. In the United States, it occurs most often in the lower portion of the esophagus. The Esophageal Cancer Action Network can offer more information about esophageal cancer and ways to promote awareness. While this disease is rare, esophageal cancer is one of the deadliest forms of cancer. In the localized stage, meaning it is only growing in the esophagus, this cancer has only a 38 percent five-year survival rate. In the regional stage, the cancer has spread to nearby lymph nodes or tissues. This stage has only a 20 percent survival rate. The distant stage, when the cancer has spread to other organs, has a 3 percent survival rate. The cause of esophageal cancer is unknown. Esophageal cancer ...
https://digestivediseasescenter.com/condition/esophageal-cancer
Endoscopic Diagnosis and Treatment of Esophageal Squamous Cell Carcinoma | Springer for Research & DevelopmentEndoscopic Diagnosis and Treatment of Esophageal Squamous Cell Carcinoma | Springer for Research & Development
Esophageal squamous cell carcinoma (ESCC) is a deadly disease, partly because it is often diagnosed late in disease stage. An accurate early diagnosis by endoscopy could detect advanced carcinoma as...
https://rd.springer.com/protocol/10.1007%2F978-1-0716-0377-2_5
Measuring tumor cell proliferation with 18F-FLT PET during radiotherapy of esophageal squamous cell carcinoma: a pilot clinical...Measuring tumor cell proliferation with 18F-FLT PET during radiotherapy of esophageal squamous cell carcinoma: a pilot clinical...
Measuring tumor cell proliferation with 18F-FLT PET during radiotherapy of esophageal squamous cell carcinoma: a pilot clinical study.
https://scholars.duke.edu/display/pub808541
Aging | Long non-coding RNA PSMA3-AS1 promotes malignant phenotypes of esophageal cancer by modulating the miR-101/EZH2 axis as...
Backgrounds: Emerging evidences has demonstrated that dysregulation of long non-coding RNAs (lncRNAs) is critically involved in esophageal squamous cell carcinoma (ESCC) progression. However, the function of lncRNA PSMA3-AS1 in ESCC is unclear. Therefore, we aimed to explore the functions and potential mechanisms of PSMA3-AS1 in ESCC cells progression.Results: Here, we found that PSMA3-AS1 expression was significantly up-regulated in ESCC tissues. Forced PSMA3-AS1 expression was correlated with tumor size, distant metastasis, and poor prognosis in ESCC patients. Functionally, PSMA3-AS1-overexpression promoted ESCC cells proliferation, invasion, and migration in vitro. Mechanistically, PSMA3-AS1 up-regulated EZH2 expression by competitively binding to miR-101.Conclusion: PSMA3-AS1 is significantly up-regulated in ESCC tissues, and the PSMA3-AS1/miR-101/EZH2 axis plays a critical role in ESCC progression. Taken together, our results may provide promising targets for ESCC therapy.Methods: PSMA3-AS1 and miR
https://www.aging-us.com/article/102716
Fatal hemorrhage in irradiated esophageal cancer patients<...
TY - JOUR. T1 - Fatal hemorrhage in irradiated esophageal cancer patients. AU - Nemoto, Kenji. AU - Takai, Yoshihiro. AU - Ogawa, Yoshihiro. AU - Kakuto, Yoshihisa. AU - Ariga, Hisanori. AU - Matsushita, Haruo. AU - Wada, Hitoshi. AU - Yamada, Shogo. PY - 1998. Y1 - 1998. N2 - Between 1980 and 1994, 423 patients with esophageal cancer were given curative radiation therapy. Of these patients, 31 died of massive hemorrhage and were used as the subjects of analysis in this study. The incidence of massive hemorrhage in all patients was 7% (31/423). In the 31 patients who died of massive hemorrhage, 27 had local tumors and two had no tumors at hemorrhage (two unknown cases). The mean time interval from the start of radiation to hemorrhage was 9.2 months. In 9 autopsy cases the origin of hemorrhage was a tear of the aorta in 5 cases, necrotic local tumor in 3 cases and esophageal ulcer in 1 case. The positive risk factors for this complication seemed to be excess total dose, infection, metallic stent, ...
https://tohoku.pure.elsevier.com/en/publications/fatal-hemorrhage-in-irradiated-esophageal-cancer-patients
Autoantibodies Response to MDM2 and p53 in the Immunodiagnosis of Esophageal Squamous Cell Carcinoma | Chai, Y.; Peng, B.; Dai,...Autoantibodies Response to MDM2 and p53 in the Immunodiagnosis of Esophageal Squamous Cell Carcinoma | Chai, Y.; Peng, B.; Dai,...
Autoantibodies Response to MDM2 and p53 in the Immunodiagnosis of Esophageal Squamous Cell Carcinoma | Chai, Y.; Peng, B.; Dai, L.; Qian, W.; Zhang, Y.; Zhang, J.-Y. | download | BookSC. Download books for free. Find books
https://el.booksc.org/book/34953805/346b29
SUV max reduction predicts long-term survival in patients of non-pCR both in the tumor and lymph nodes after neoadjuvant...SUV max reduction predicts long-term survival in patients of non-pCR both in the tumor and lymph nodes after neoadjuvant...
A pathological complete response (pCR) after neoadjuvant chemoradiotherapy (NACRT) ensures long-term survival in esophageal squamous cell carcinoma (ESCC) patients following esophagectomy, but pCR patients are a minority. The aim here was to identify prognostic factors in patients with non-pCR ESCC after NACRT. This is a retrospective study. Investigated were 5-year overall survival (OS), disease-specific survival (DSS), and relapse-free survival (RFS) among non-pCR ESCC patients divided into pT0N0, primary site pCR (pT0N+), lymph node pCR (pT+N0), and non-pCR in both the tumor and lymph node (pT+N+) subgroups after NACRT and esophagectomy. Focusing on the SUVmax reduction rate in the primary tumor in 88 patients who underwent FDG-PET before and after NACRT, we used univariate and multivariate Cox proportional hazard models to identify prognostic factors. Although there were no significant survival differences among non-pCR ESCC patients with pT0N+, pT+N0, or pT+N+, survival rate among pT+N+patients was
https://wjso.biomedcentral.com/articles/10.1186/s12957-021-02208-3
Programmed cell death 4 (PDCD4) expression during multistep Barretts carcinogenesis | Journal of Clinical PathologyProgrammed cell death 4 (PDCD4) expression during multistep Barretts carcinogenesis | Journal of Clinical Pathology
The progression of BM to BAc passes through well-established histological changes, in which dysplasia is considered the most advanced phenotypic change before invasive cancer sets in.1 2 36 However, not all dysplastic lesions progress to cancer, and a better understanding of the molecular biology of this disease may lead to improvements in the diagnosis, treatment and prognosis of patients with BE.37. PDCD4 has been characterised as a new tumour suppressor gene, which is downregulated in several human malignancies.19-24 Its overexpression inhibits neoplastic transformation in both cancer cell lines and in vivo models.10 38 39. Low PDCD4 protein levels (assessed by western blot and qRT-PCR analyses) have been observed in oesophageal squamous cell carcinoma cell lines.18 In a large series of oesophageal tumours, we recently found that PDCD4 protein was completely lost or significantly reduced in almost 60% of the tumour samples considered.25 As in the lung cancer setting,20 no significant ...
http://jcp.bmj.com/content/63/8/692
Histologic subtypes as determinants of outcome in esophageal carcinoma patients with pathologic complete response after...Histologic subtypes as determinants of outcome in esophageal carcinoma patients with pathologic complete response after...
The outcome of patients with localized carcinoma of the esophagus remains dismal despite some advances in chemotherapy agents, an improved understanding of chemoradiobiology, and improvement in multidisciplinary care. The pathCR rates are approximately 27%.14 The therapeutic approach has been empiric for decades. Any substantial gains may not be anticipated by continued empiric approaches. Therefore, more attention to clinical biology may be needed and, more important, molecular biology and patient genetics. Deriving therapy based on the molecular biology of the tumor and patient genetics is a major challenge but a much-needed effort. However, at the current time, there is an opportunity to study the clinical biology of esophageal cancer.. ACA and SCC appear to have a distinct clinical profile. ACA occurs predominantly in white men and is often associated with increased body mass index and chronic gastroesophageal reflux disease, whereas SCC, although more common in men, is predominantly a ...
http://onlinelibrary.wiley.com/doi/10.1002/cncr.21601/full?globalMessage=0
Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide...
TY - JOUR. T1 - Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway. AU - Nguyen, Dao M.. AU - Chen, G. Aaron. AU - Reddy, Rishindra. AU - Tsai, Wilson. AU - Schrump, William D.. AU - Cole, George. AU - Schrump, David S.. AU - Jones, David A.. AU - Mentzer, Steven J.. AU - Harpole, David H.. PY - 2004/2. Y1 - 2004/2. N2 - Background: Constitutive activation of the phosphoinositide 3-kinase/protein kinase B survival signal transduction pathway influences the intrinsic chemoresistance of cancer cells. This study evaluates the effect of LY294002, a pharmacologic inhibitor of phosphoinositide 3-kinase, on the sensitivity of lung and esophageal cancer cells to paclitaxel (Taxol) in vitro. Materials and Methods: Cell viability and apoptosis of cancer cells treated with paclitaxel + LY294002 combinations were quantitated by methyl-thiazol-diphenyl-tetrazolium and ...
https://miami.pure.elsevier.com/en/publications/potentiation-of-paclitaxel-cytotoxicity-in-lung-and-esophageal-ca
Squamous Dysplasia-The Precursor Lesion for Esophageal Squamous Cell Carcinoma | Cancer Epidemiology, Biomarkers & PreventionSquamous Dysplasia-The Precursor Lesion for Esophageal Squamous Cell Carcinoma | Cancer Epidemiology, Biomarkers & Prevention
Numerous molecular alterations in ESCC tumors have been identified. Among them, TP53 alterations are the most common. One study of 56 ESCC cases from north central China found at least 1 genetic alteration in TP53 in 96% of the tumors studied, including mutations (77%), allelic loss within the gene (73%), and/or LOH at the TP53 microsatellite marker (80%); and three quarters of the cases had 2 or more such alterations (11). In a study conducted in northeastern Iran, 90% of the 119 ESCC cases evaluated had a TP53 mutation, including 11 with 2 or 3 mutations (12). The TP53 mutation pattern observed in this study was heterogeneous, in a manner suggestive of environmental exposures. Typical hotspots were only infrequently mutated, whereas 40% of altered bases were at mutagenesis sites known to be associated with polycyclic aromatic hydrocarbon exposure, and the mutation patterns differed by the reported temperature of the tea consumed. Another study of 60 ESCCs from north central China observed at ...
http://cebp.aacrjournals.org/content/22/4/540?rss=1
Does paclitaxel improve the chemoradiotherapy of locoregionally advanced esophageal cancer? A nonrandomized comparison with...
TY - JOUR. T1 - Does paclitaxel improve the chemoradiotherapy of locoregionally advanced esophageal cancer? A nonrandomized comparison with fluorouracil-based therapy. AU - Adelstein, David J.. AU - Rice, Thomas W.. AU - Rybicki, Lisa A.. AU - Larto, Marjorie A.. AU - Ciezki, Jay. AU - Saxton, Jerrold. AU - DeCamp, Malcolm. AU - Vargo, John J.. AU - Dumot, John A.. AU - Zuccaro, Gregory. PY - 2000/1/1. Y1 - 2000/1/1. N2 - Purpose: A phase II trial of accelerated fractionation radiation with concurrent cisplatin and paclitaxel chemotherapy was performed to investigate the role of the paclitaxel, when substituted for fluorouracil (5-FU), in the chemoradiotherapy of esophageal cancer. Patients and Methods: Patients with an esophageal ultrasound stage of T3 or N1 or M1 (nodal) esophageal cancer were treated with two courses of a cisplatin infusion (20 mg/m2/d for 4 days) and paclitaxel (175 mg/m2 over 24 hours) concurrent with a split course of accelerated fractionation radiation (1.5 Gy bid to a ...
https://www.scholars.northwestern.edu/en/publications/does-paclitaxel-improve-the-chemoradiotherapy-of-locoregionally-a
117 of the best peer-reviewed specialists in esophageal cancer surgery |TopDoctors117 of the best peer-reviewed specialists in esophageal cancer surgery |TopDoctors
Find and book the best doctor specialised in esophageal cancer surgery. Compare patient reviews, insurance, prices and get your referral letter instantly.
https://www.topdoctors.es/en/cirugia-del-cancer-esofagico
Oesophago-gastric cancer referralsOesophago-gastric cancer referrals
Oesophago-gastric cancer referrals should be made using the standard two week wait referral proforma from the Healthy London Partnership website
https://www.guysandstthomas.nhs.uk/our-services/cancer/cancer-types/oesophago-gastric/referrals.aspx
A case of esophageal adenocarcinoma metastasized to the scalp<...A case of esophageal adenocarcinoma metastasized to the scalp<...
TY - JOUR. T1 - A case of esophageal adenocarcinoma metastasized to the scalp. AU - Park, Jin Mo. AU - Kim, Dae Suk. AU - Oh, Sang Ho. AU - Kwon, Yeon Sook. AU - Lee, Kwang Hoon. PY - 2009/12/1. Y1 - 2009/12/1. N2 - Cutaneous metastases from internal malignancies are, occurring in 0.5% to 9% of cases. Lung, breast, and colorectal cancers are common primary tumors that metastasize to the skin; cutaneous metastasis usually occurs on the chest wall and abdomen as asymptomatic nodular patterns. Esophageal cancer is not nearly as common as breast, lung, and colorectal cancers, and esophageal cancer rarely metastasizes to the skin. Cutaneous metastasis of esophageal cancer is rare and metastasis to the scalp is extremely rare. Only a few cases of cutaneous metastases of esophageal cancer have been reported in Korea. Most of the cases involved cutaneous metastases arising from esophageal squamous cell carcinoma; however, there have been several reports describing cutaneous metastases from esophageal ...
https://yonsei.pure.elsevier.com/en/publications/a-case-of-esophageal-adenocarcinoma-metastasized-to-the-scalp
Plus itPlus it
Background: A steep increase in the incidence of esophageal adenocarcinoma has been observed between 1973 and 2001, but recent trends have not been reported. Our aim was to examine recent trends in esophageal adenocarcinoma incidence.. Methods: We used the Surveillance Epidemiology and End Results database of the National Cancer Institute to identify all patients who were diagnosed with esophageal adenocarcinoma between 1973 and 2006. Incidence trends were analyzed for esophageal adenocarcinoma overall and by stage using joinpoint regression.. Results: Overall esophageal adenocarcinoma incidence increased from 3.6 per million in 1973 to 25.6 per million in 2006. Incidence trend analysis, however, suggests that the increase has slowed, from an 8.2% annual increase prior to 1996 to 1.3% increase in subsequent years (P = 0.03). Stage-specific trend analyses suggest that the change in overall esophageal adenocarcinoma incidence largely reflects a plateau in the incidence of early stage disease. Its ...
http://cebp.aacrjournals.org/content/early/2010/05/21/1055-9965.EPI-10-0012
LeiomyomaLeiomyoma
ISBN 0-7216-2921-0. Radiologic Pathology Archives: Esophageal Neoplasms: Radiologic-Pathologic Correlation Rachel B. Lewis, ... Accessed 2017-07-08 Radiologic Pathology Archives: Esophageal Neoplasms: Radiologic-Pathologic Correlation Rachel B. Lewis, ... Mesenchymal neoplasms of the gallbladder are rare and in particular leiomyomas of the gallbladder have been rarely reported, ... Esophageal Leiomyoma at eMedicine (Articles with short description, Short description is different from Wikidata, Dermal and ...
https://en.wikipedia.org/wiki/Leiomyoma
List of MeSH codes (C04)List of MeSH codes (C04)
... choroid neoplasms MeSH C04.588.364.978.400 - iris neoplasms MeSH C04.588.443.353 - esophageal neoplasms MeSH C04.588.443.392 - ... gallbladder neoplasms MeSH C04.588.274.476 - gastrointestinal neoplasms MeSH C04.588.274.476.205 - esophageal neoplasms MeSH ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C04)
List of MeSH codes (C06)List of MeSH codes (C06)
... common bile duct neoplasms MeSH C06.301.120.401 - gallbladder neoplasms MeSH C06.301.371.205 - esophageal neoplasms MeSH ... esophageal neoplasms MeSH C06.405.117.468 - esophageal perforation MeSH C06.405.117.468.524 - mallory-weiss syndrome MeSH ... esophageal neoplasms MeSH C06.405.249.308 - gastrointestinal stromal tumors MeSH C06.405.249.411 - intestinal neoplasms MeSH ... common bile duct neoplasms MeSH C06.130.320.120 - bile duct neoplasms MeSH C06.130.320.120.280 - common bile duct neoplasms ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C06)
Esophageal cancerEsophageal cancer
See: "C16 - Malignant neoplasm of the stomach". ICD-10 Version: 2015. World Health Organization. Archived from the original on ... Wikimedia Commons has media related to Esophageal cancer. NCI esophageal cancer Cancer.Net: Esophageal Cancer Esophageal Cancer ... esophageal squamous-cell carcinoma) comprises 60-70% of all cases of esophageal cancer worldwide, while EAC (esophageal ... and T3 stages of esophageal cancer Stage T4 esophageal cancer Esophageal cancer with spread to lymph nodes Prevention includes ...
https://en.wikipedia.org/wiki/Esophageal_cancer
NeoplasmNeoplasm
"Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma". Int J Clin Exp Pathol ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term neoplasm is a synonym of tumor. Neoplasia denotes the process of the formation of neoplasms/tumors, and the process is ... The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that ...
https://en.wikipedia.org/wiki/Neoplasm
List of diseases (E)List of diseases (E)
Esophageal atresia Esophageal disorder Esophageal duodenal atresia abnormalities of hands Esophageal neoplasm Esophageal ... protoporphyria Escher-Hirt syndrome Escherichia coli infection Esophageal atresia associated anomalies Esophageal atresia ...
https://en.wikipedia.org/wiki/List_of_diseases_(E)
Endoscopic submucosal dissectionEndoscopic submucosal dissection
... especially for large or ulcerative neoplasms. Recently, the ESD technique is applied to esophageal or colorectal neoplasms in ... The resected size and shape can be controlled, en bloc resection is possible even in a large neoplasm, and neoplasms with ... So this technique can be applied to the resection of complex neoplasms such as large neoplasms, ulcerative non-lifting ... For a reliable en bloc resection of GI neoplasms, a new method of ER called endoscopic submucosal dissection (ESD) has been ...
https://en.wikipedia.org/wiki/Endoscopic_submucosal_dissection
Digestive system neoplasmDigestive system neoplasm
... esophageal cancer gastric cancer small intestinal cancer colorectal cancer anal cancer Esophageal cancers commonly present ... Digestive system neoplasms are tumors which affect the digestive system. There are many different and various pathologic ... classification for digestive system neoplasms. Considering the part of the digestive system that they origin, they are ...
https://en.wikipedia.org/wiki/Digestive_system_neoplasm
ChromoendoscopyChromoendoscopy
Toluidine blue stains nuclei of malignant cells blue, and is used in oral and esophageal squamous cell carcinoma. Crystal ... violet is absorbed into intestinal and neoplastic cells and is used to identify Barrett's esophagus and colonic neoplasms.[ ...
https://en.wikipedia.org/wiki/Chromoendoscopy
TMEM229BTMEM229B
... esophageal carcinoma, gastric carcinoma, glioblastoma, liver carcinoma, lymphoma, melanoma, small cell lung carcinoma, T-cell ... B-cell neoplasm, breast carcinoma, Burkitt's lymphoma, colorectal adenocarcinoma, carcinoma, cutaneous T cell lymphoma, ...
https://en.wikipedia.org/wiki/TMEM229B
EdoxabanEdoxaban
... malignant neoplasms at high risk of bleeding, recent brain injury or spinal injury, recent brain, spinal or ophthalmic surgery ... known or suspected esophageal varices, arteriovenous malformations, aneurysms or major intraspinal or intracerebral vascular ...
https://en.wikipedia.org/wiki/Edoxaban
EndoscopeEndoscope
... esophageal varices, esophageal hiatal hernia, esophageal leiomyoma, esophageal cancer, cardiac cancer, etc. Stomach and ... Small intestine: small intestine neoplasms, smooth muscle tumors, sarcomas, polyps, lymphomas, inflammation, etc. Large ... And a wireless oesophageal pH measuring devices can now be placed endoscopically, to record ph trends in an area remotely. ... "Esophageal pH Test: MedlinePlus Medical Test". medlineplus.gov. Retrieved 2022-06-30. "Overview of Endoscopy Haptics Simulator ...
https://en.wikipedia.org/wiki/Endoscope
H19 (gene)H19 (gene)
In contrast to most other cancers, adrenocortical neoplasms appear to have decreased expression of H19. To determine a possible ... esophageal cancer and lung cancer. Cellular DNA integrity is often compromised in cancer. Genome instability can refer to the ... Overexpression of H19 appears to be important in the development of esophageal and colorectal cancer cells Cells expressing H19 ... "Loss of H19 imprinting in esophageal cancer". Cancer Res. 56 (3): 480-482. PMID 8564957. Lottin S, Adriaenssens E, Dupressoir T ...
https://en.wikipedia.org/wiki/H19_(gene)
BrachytherapyBrachytherapy
For esophageal cancer radiation treatment, brachytherapy is one option for effective treatment, involves definitive ... GammaTile is FDA-cleared to treat newly diagnosed, operable malignant intracranial neoplasms (i.e., brain tumors) and operable ... Brachytherapy is commonly used as an effective treatment for cervical, prostate, breast, esophageal and skin cancer and can ... Previously Irradiated Intracranial Neoplasms on a Prospective Clinical Trial". Brachytherapy. 18 (3): S35-S36. doi:10.1016/j. ...
https://en.wikipedia.org/wiki/Brachytherapy
DEC1DEC1
Deleted in esophageal cancer 1 is a protein that in humans is encoded by the DEC1 gene. The function of this gene is not known ... "DEC1 expression in 1p-aberrant oligodendroglial neoplasms". Histol. Histopathol. 20 (4): 1173-7. PMID 16136500. Yang L, Leung ... "Entrez Gene: DEC1 deleted in esophageal cancer 1". Qian Y, Zhang J, Yan B, Chen X (2008). "DEC1, a basic helix-loop-helix ... This gene is located in a region commonly deleted in esophageal squamous cell carcinomas. Gene expression is reduced or absent ...
https://en.wikipedia.org/wiki/DEC1
CSNK1DCSNK1D
... esophageal cancer as well as head and neck cancer. Besides those, reduced CK1δ activity owing to the site N172D mutation of CK1 ... hematopoietic malignancies and lymphoid neoplasms. Also decreased CK1δ mRNA expression levels have been observed in some cancer ...
https://en.wikipedia.org/wiki/CSNK1D
Long-term effects of alcoholLong-term effects of alcohol
Negative effects include increased risk of liver diseases, oropharyngeal cancer, esophageal cancer and pancreatitis. Conversely ... and malignant neoplasms. The psychiatric disorders associated with alcoholism include major depression, dysthymia, ...
https://en.wikipedia.org/wiki/Long-term_effects_of_alcohol
TelangiectasiaTelangiectasia
Some telangiectasias are due to developmental abnormalities that can closely mimic the behaviour of benign vascular neoplasms. ... The syndrome recognises the significantly co-presenting symptoms of calcinosis, Raynaud's phenomenon, esophageal dysmotility, ...
https://en.wikipedia.org/wiki/Telangiectasia
Hemiazygos veinHemiazygos vein
It receives the 9th, 10th, and 11th posterior intercostal veins and the subcostal vein of the left side, and some esophageal ... hemiazygos system displayed by chest or abdominal X-ray films can be misdiagnosed as a mediastinal or retroperitoneal neoplasm ...
https://en.wikipedia.org/wiki/Hemiazygos_vein
List of diseases (A)List of diseases (A)
Abdominal neoplasms Aberrant subclavian artery Ablepharon macrostomia syndrome Abnormal systemic venous return Abruzzo-Erickson ... familial esophageal Achalasia microcephaly Achard syndrome Achard-Thiers syndrome Acheiropodia Achondrogenesis Achondrogenesis ... X-linked Adrenal incidentaloma Adrenal insufficiency Adrenal macropolyadenomatosis Adrenal medulla neoplasm Adrenocortical ... Abdominal cystic lymphangioma Abdominal defects Abdominal musculature absent microphthalmia joint laxity Abdominal neoplasm / ...
https://en.wikipedia.org/wiki/List_of_diseases_(A)
StenosisStenosis
... secondary to radiation therapy infection inflammation ischemia neoplasm - in such cases, the stenosis is often said to be " ... Phimosis Non-communicating hydrocephalus due to aqueductal stenosis Stenosing tenosynovitis Atherosclerosis Esophageal ... "malignant" or "benign", although this attribute actually refers to the neoplasm itself. smoking ureteral urethral Stenoses of ...
https://en.wikipedia.org/wiki/Stenosis
Chronic mucocutaneous candidiasisChronic mucocutaneous candidiasis
Patients with autosomal-dominant mucocutaneous candidiasis may be at risk for epidermoid esophageal cancer due to the ... neoplasms, and others. In most patients, chronic mucocutaneous candidiasis is correlated to abnormalities in cell-mediated ... Chronic mucocutaneous candidiasis and oesophageal cancer. Med Mycol. 2008 Feb;46(1):85-91. doi: 10.1080/13693780701616023. PMID ...
https://en.wikipedia.org/wiki/Chronic_mucocutaneous_candidiasis
MBD4MBD4
... mRNA expression is reduced in colorectal neoplasms due to methylation of the promoter region of MBD4. A majority of ... MBD4 mutations also occur in tumor samples of melanoma, ovarian, lung, esophageal and prostate cancers at frequencies between ... compared to histologically normal tissue from individuals who never had a colonic neoplasm. This indicates that an epigenetic ...
https://en.wikipedia.org/wiki/MBD4
Mir-25 microRNA precursor familyMir-25 microRNA precursor family
"MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma". Biochemical and Biophysical Research ... MicroRNA expression pattern in intraductal papillary mucinous neoplasm]". The Korean Journal of Gastroenterology = Taehan ... "MicroRNA analysis of microdissected normal squamous esophageal epithelium and tumor cells". American Journal of Cancer Research ...
https://en.wikipedia.org/wiki/Mir-25_microRNA_precursor_family
Gastrointestinal cancerGastrointestinal cancer
An "esophageal cancer belt", in which the incidence of esophageal squamous cell carcinoma (SCC) is more than a hundred times ... from patients who had never had a gastric malignant neoplasm), non-tumor tissue adjacent to a gastric cancer, and gastric ... By the time esophageal cancer is usually detected, though, it might have spread beyond the esophageal wall, and the survival ... Esophageal cancer is the sixth-most-common cancer in the world, and its incidence is increasing. Some three to five males are ...
https://en.wikipedia.org/wiki/Gastrointestinal_cancer
CancerCancer
They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often ... For example, mass effects from lung cancer can block the bronchus resulting in cough or pneumonia; esophageal cancer can cause ... Frequent consumption of scalding hot tea may produce esophageal cancer. Generally, it is believed that cancer arises, or a pre- ...
https://en.wikipedia.org/wiki/Cancer
Carneys triadCarney's triad
Carney triad (CT) is characterized by the coexistence of three types of neoplasms, mainly in young women, including gastric ... In addition to these three classical tumors, there is an increased incidence of pheochromocytoma, esophageal leiomyoma and ... The Carney complex is a distinct entity, characterized by myxomatous neoplasms (cardiac, endocrine, cutaneous and neural), and ...
https://en.wikipedia.org/wiki/Carney's_triad
List of cancer typesList of cancer types
Esophageal cancer Head and neck cancer Nasopharyngeal carcinoma Oral cancer Oropharyngeal cancer Paranasal sinus and nasal ... Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ...
https://en.wikipedia.org/wiki/List_of_cancer_types
Squamous cell carcinomaSquamous cell carcinoma
Esophageal cancer may be due to either esophageal squamous cell carcinoma (ESCC) or adenocarcinoma (EAC). SCCs tend to occur ... Berman JJ (November 2004). "Tumor taxonomy for the developmental lineage classification of neoplasms". BMC Cancer. 4 (1): 88. ... A type of thyroid cancer Esophageal squamous-cell carcinoma: A type of esophageal cancer Squamous-cell carcinoma of the vagina ... "Esophageal Cancer". The Lecturio Medical Concept Library. 26 October 2020. Retrieved 6 August 2021. Pooler C, Hannon RA, Porth ...
https://en.wikipedia.org/wiki/Squamous_cell_carcinoma
Helicobacter pyloriHelicobacter pylori
Ma Q, Zhang C, Fang S, Zhong P, Zhu X, Lin L, Xiao H (March 2017). "Primary esophageal mucosa-associated lymphoid tissue ... March 2008). "Prevalence of nonpolypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults". JAMA ... The incidence of acid reflux disease, Barrett's esophagus, and esophageal cancer have been rising dramatically at the same time ... Delaney B, McColl K (August 2005). "Review article: Helicobacter pylori and gastro-oesophageal reflux disease". Alimentary ...
https://en.wikipedia.org/wiki/Helicobacter_pylori
P16P16
Xu R, Wang F, Wu L, Wang J, Lu C (January 2013). "A systematic review of hypermethylation of p16 gene in esophageal cancer". ... However, p16 can be expressed in other neoplasms and in several normal human tissues. More than a third of urinary bladder SCCs ... In 2013, a meta-analysis revealed an increased frequency of DNA methylation of the p16 gene in esophageal cancer. As the degree ... Homozygous deletions of p16 are frequently found in esophageal cancer and gastric cancer cell lines. Germline mutations in ...
https://en.wikipedia.org/wiki/P16
Radiation therapyRadiation therapy
Hypopituitarism commonly develops after radiation therapy for sellar and parasellar neoplasms, extrasellar brain tumours, head ... November 2017). "Automatic treatment planning facilitates fast generation of high-quality treatment plans for esophageal cancer ...
https://en.wikipedia.org/wiki/Radiation_therapy
List of skin conditionsList of skin conditions
... palmoplantar keratoderma associated with esophageal cancer, tylosis, tylosis-esophageal carcinoma) Hystrix-like ichthyosis- ... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ... neoplasms invading or aberrantly present in the dermis. Acquired progressive lymphangioma (benign lymphangioendothelioma) Acral ...
https://en.wikipedia.org/wiki/List_of_skin_conditions
Proton therapyProton therapy
Two prominent examples are pediatric neoplasms (such as medulloblastoma) and prostate cancer. Irreversible long-term side ... "Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer". ClinicalTrials.gov. August 2020. "Dose Escalation ... pancreatic cancer and esophageal cancer. Post-treatment liver decompensation, and subsequent liver failure, is a risk with ... Mayo Clinic Esophageal cancer-by NRG Oncology, Abramson Cancer Center, University of Pennsylvania Breast cancer-by University ...
https://en.wikipedia.org/wiki/Proton_therapy
Thymidine kinase in clinical chemistryThymidine kinase in clinical chemistry
Lipkin M, Deschner E, Troncale F (1970). "Cell differentiation and the development of colonic neoplasms". CA: A Cancer Journal ... cervical and esophageal cancers. There are several non-malignant causes for elevation of thymidine kinase in serum including ... "Serum thymidine kinase 1 levels correlate with clinical characteristics of esophageal squamous cell carcinoma". Int J Clin Exp ... "Biochemical measure of the volume doubling time of human pulmonary neoplasms". Cancer. 55 (7): 1530-5. doi:10.1002/1097-0142( ...
https://en.wikipedia.org/wiki/Thymidine_kinase_in_clinical_chemistry
List of MeSH codes (C23)List of MeSH codes (C23)
... neoplasm seeding MeSH C23.550.727.650.895 - neoplasms, unknown primary MeSH C23.550.727.655 - neoplasm recurrence, local MeSH ... esophageal MeSH C23.300.415.250.900 - zenker diverticulum MeSH C23.300.415.500 - diverticulum, stomach MeSH C23.300.415.750 - ... neoplasm metastasis MeSH C23.550.727.650.560 - lymphatic metastasis MeSH C23.550.727.650.645 - neoplasm circulating cells MeSH ... C23.550.727.670 - neoplasm regression, spontaneous MeSH C23.550.727.700 - neoplasm, residual MeSH C23.550.737.500 - retrograde ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C23)
Guanylate cyclase 2CGuanylate cyclase 2C
2009). "Guanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms". ... acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal ...
https://en.wikipedia.org/wiki/Guanylate_cyclase_2C
Yu BaofaYu Baofa
In 1984, his mother was diagnosed with esophageal cancer and later died. Soon after, his best friend's father died of cancer as ... "US Patent for Combinations and methods for treating neoplasms Patent (Patent # 7,927,612 issued April 19, 2011) - Justia ... "US Patent for Combinations and methods for treating neoplasms Patent (Patent # 6,811,788 issued November 2, 2004) - Justia ... "US Patent Application for COMPOSITIONS AND METHODS FOR TARGETING OF TREATING NEOPLASMS Patent Application (Application # ...
https://en.wikipedia.org/wiki/Yu_Baofa
OsteosarcomaOsteosarcoma
Overall survival prognosis is about 30%. Deaths due to malignant neoplasms of the bones and joints account for an unknown ... Ranen E, Lavy E, Aizenberg I, Perl S, Harrus S (2004). "Spirocercosis-associated esophageal sarcomas in dogs. A retrospective ... Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and ...
https://en.wikipedia.org/wiki/Osteosarcoma
LaryngitisLaryngitis
One possible explanation of chronic laryngitis is that inflammation is caused by gastro-oesophageal reflux, which causes ... Spasmodic dysphonia Reflux laryngitis Chronic allergic laryngitis Neoplasm Croup: This presents with a barking cough, ...
https://en.wikipedia.org/wiki/Laryngitis
MIRN21MIRN21
January 2011). "Prognostic significance of differentially expressed miRNAs in esophageal cancer". International Journal of ... it has been demonstrated as an independent prognostic factor in patients with pancreatic neuroendocrine neoplasms. miR-21 has ... "Prognostic relevance of proliferation-related miRNAs in pancreatic neuroendocrine neoplasms". European Journal of Endocrinology ...
https://en.wikipedia.org/wiki/MIRN21
Nikolay DevyatkovNikolay Devyatkov
This area of his research has its modern development in the devices for diagnostic gastroenterology: esophageal pH monitoring, ... for the local microwave thermotherapy of malignant neoplasms and diseases of the prostate "Yachta-5" for the general and local ... esophageal motility study, electrogastroenterography and other, that has brandname "Gastroscan" in Russia and are the main ... operating local electromagnetic hyperthermia of malignant neoplasms. At present, this direction is actively developed and ...
https://en.wikipedia.org/wiki/Nikolay_Devyatkov
Infectious causes of cancerInfectious causes of cancer
Spirocerca lupi is associated with esophageal cancer in dogs, at least within the southern United States. A novel type of case ... An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation". The ...
https://en.wikipedia.org/wiki/Infectious_causes_of_cancer
GastrinomaGastrinoma
Patients with gastrinomas that are also known to be part of neuroendocrine neoplasms must have to deal with two factors related ... Hematemesis Gastroesophageal reflux disease Esophageal complications (Barrett's esophagus, esophagitis, stricture formation) ... arise as primary neoplasms in lymph nodes of the pancreaticoduodenal region (gastrinoma triangle). Most gastrinomas are ...
https://en.wikipedia.org/wiki/Gastrinoma
Browsing by Subject Esophageal NeoplasmsBrowsing by Subject "Esophageal Neoplasms"
Oesophageal cancer is endemic in some regions of the Islamic Republic of Iran and efforts have been made to find factors that ... Correlation of serum alkaline phosphatase with clinicopathological characteristics of patients with oesophageal cancer  ...
https://extranet.who.int/iris/restricted/browse?authority=Esophageal+Neoplasms&type=mesh
Results of search for 'su:{Esophageal neoplasms}' › WHO HQ Library catalog
Histological typing of gastric and oesophageal tumours / H. Watanabe, J. R. Jass and L. H. Sobin, in collaboration with ...
https://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7BEsophageal%20neoplasms%7D
Aspiration Pneumonitis and Pneumonia: Overview of Aspiration Pneumonia, Predisposing Conditions for Aspiration Pneumonia,...Aspiration Pneumonitis and Pneumonia: Overview of Aspiration Pneumonia, Predisposing Conditions for Aspiration Pneumonia,...
... a history of esophageal diseases including achalasia [15] or esophageal web, being a nursing home patient, and being ... This procedure is useful when ruling out the presence of an obstructing neoplasm in anaerobic bacterial pneumonia with lung ... Esophageal conditions associated with aspiration pneumonia include the following:. * Dysphagia: Oropharyngeal dysphagia has ... when airway obstruction due to a foreign body is suspected in patients with chemical pneumonitis or for ruling out a neoplasm ...
https://www.medscape.com/answers/296198-38034/which-microorganisms-cause-aspiration-pneumonia
Browsing by SubjectBrowsing by Subject
JavaScript is disabled for your browser. Some features of this site may not work without it ...
https://apps.who.int/iris/browse?rpp=20&offset=2030&etal=-1&sort_by=-1&type=mesh&starts_with_previous=H&order=ASC
Esophageal Cancer | MedlinePlusEsophageal Cancer | MedlinePlus
Early esophageal cancer does not have symptoms. Factors that increase risk include heavy drinking and smoking. Learn how you ... ClinicalTrials.gov: Esophageal Neoplasms (National Institutes of Health) Journal Articles References and abstracts from MEDLINE ... Esophageal Cancer (Society of Thoracic Surgeons) Also in Spanish * Esophageal Cancer (National Cancer Institute) Also in ... Stages of Esophageal Cancer (National Cancer Institute) Also in Spanish * Tests for Esophageal Cancer (American Cancer Society) ...
https://medlineplus.gov/esophagealcancer.html
Long-term health-related quality of life for disease-free esophageal cancer patientsLong-term health-related quality of life for disease-free esophageal cancer patients
Esophageal Neoplasms / psychology* * Esophageal Neoplasms / surgery* * Esophagectomy / psychology* * Female * Follow-Up Studies ... Long-term health-related quality of life for disease-free esophageal cancer patients World J Surg. 2011 Aug;35(8):1853-60. doi ... The aim of this study was to investigate HRQL in patients alive at least 1 year after surgical resection for esophageal cancer ... Patients completed general (QLQ-C30) and esophageal cancer-specific (QLQ-OES18, OG25) questionnaires. A numeric score (0-100) ...
https://pubmed.ncbi.nlm.nih.gov/21553202/?dopt=Abstract
ADP-A2M4CD8 as Monotherapy or in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS) - Full...ADP-A2M4CD8 as Monotherapy or in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS) - Full...
Esophageal Neoplasms. Endometrial Neoplasms. Stomach Neoplasms. Neuroendocrine Tumors. Neuroectodermal Tumors. Neoplasms, Germ ... Neoplasms by Histologic Type. Neoplasms. Neoplasms, Nerve Tissue. Nevi and Melanomas. Endocrine Gland Neoplasms. Neoplasms by ... Head and Neck Neoplasms. Gastrointestinal Neoplasms. Digestive System Neoplasms. Digestive System Diseases. Esophageal Diseases ... Genital Neoplasms, Female. Urogenital Neoplasms. Endocrine System Diseases. Gonadal Disorders. ...
https://clinicaltrials.gov/ct2/show/NCT04044859?spons=Adaptimmune&rank=1
NIOSHTIC-2 Search Results - Full View
... esophageal cancer; grinding; cutting fluids; machining fluids; coolants; esophageal neoplasms; automobile workers; nitrosamine ... RESULTS: Esophageal cancer was found to be significantly associated with exposure to both soluble and synthetic MWF in grinding ... Those with 12 or more years exposure to soluble MWF in grinding operations experienced a 9.3-fold relative risk of esophageal ... Results are reported from a nested case-control study of 60 esophageal cancer deaths among 46,384 automobile manufacturing ...
http://www2a.cdc.gov/nioshtic-2/BuildQyr.asp?s1=metalworking&t3=1&f8=KW&f1=TI&s5=metalworking&t7=1&Startyear=&t1=1&f6=KW&s2=%27metal+working%27&t4=1&f9=%2A&terms=12&Adv=1&ct=&B1=Search&f2=TI&s6=%27metal+working%27&t8=0&t2=1&f7=KW&Limit=500&Sort=DP+DESC&s3=cutting&t5=1&f3=TI&s7=cutting&s4=machining&t6=1&EndYear=&f4=TI&s8=machining&f5=KW&s9=%27oil%2A%27+or+%27fluid%2A%27+or+%27coolant%2A%27+or+%27liquid%2A%27&D1=10&PageNo=26&RecNo=252&View=f&
Esophageal Stricture Medication: Proton pump inhibitorsEsophageal Stricture Medication: Proton pump inhibitors
... extrinsic diseases that compromise the esophageal lumen by direct invasion or lymph node enlargement; and (3) diseases that ... intrinsic diseases that narrow the esophageal lumen through inflammation, fibrosis, or neoplasia; (2) ... Disease processes that can produce esophageal strictures can be grouped into 3 general categories: (1) ... Predictors of postoperative stricture after esophageal endoscopic submucosal dissection for superficial squamous cell neoplasms ...
https://emedicine.medscape.com/article/175098-medication
SciELO - Brazil - PROGNOSTIC FACTORS AND SURVIVAL ANALYSIS IN ESOPHAGEAL CARCINOMA PROGNOSTIC FACTORS AND SURVIVAL ANALYSIS IN...SciELO - Brazil - PROGNOSTIC FACTORS AND SURVIVAL ANALYSIS IN ESOPHAGEAL CARCINOMA PROGNOSTIC FACTORS AND SURVIVAL ANALYSIS IN...
Factors associated to neoplasm High tumor size and high oncologic stage was associated with high mortality in SCC. This is in ... Assess prognostic variables in esophageal cancer patients. Methods:. Retrospective review of all patients with esophageal ... PROGNOSTIC FACTORS AND SURVIVAL ANALYSIS IN ESOPHAGEAL CARCINOMA Francisco TUSTUMI Cancer Institute of São Paulo State, São ... Esophageal carcinoma is a poor prognosis disease. In our study, after five years of follow-up, overall survival is next to 20 ...
https://www.scielo.br/j/abcd/a/dLzpj3CqPtqcjrNNKd8KJRG/?lang=en
Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Cancer of the Stomach or EsophagusCombination Chemotherapy in Treating Patients With Metastatic or Recurrent Cancer of the Stomach or Esophagus
Esophageal Diseases. *Esophageal Neoplasms. *Stomach Neoplasms. .map{width:100%;height:300px;margin-bottom:15px;} Name. ...
http://www.knowcancer.com/cancer-trials/NCT00005607/
masahide - PubAg Search Resultsmasahide - PubAg Search Results
acetic acid; bacteremia; blood; clinical nutrition; dietary supplements; drug therapy; esophageal neoplasms; gastrointestinal ... Impact of synbiotics treatment on bacteremia induced during neoadjuvant chemotherapy for esophageal cancer: A randomised ... T-lymphocytes; absorbents; adenocarcinoma; data collection; genome; lung neoplasms; lungs; peptides; protein synthesis; ... bacteremia during neoadjuvant chemotherapy for esophageal cancer.Patients requiring neoadjuvant chemotherapy for esophageal ...
https://pubag.nal.usda.gov/?per_page=50&q=masahide&search_field=all_fields&sort=date-desc
Spence, A. D.<...
Esophageal Neoplasms Medicine & Life Sciences 100% * Cohort Studies Medicine & Life Sciences 40% ... The role of 5α-reductase inhibitors in gastro-oesophageal cancer risk: a nested case-control study. Busby, J., Karasneh, R., ... Blood Biomarkers for Early Detection of Oesophageal Cancer: A Systematic Review: A systematic review. Kunzmann, A. T., ... Angiotensin receptor blocker use and gastro-oesophageal cancer survival: a population-based cohort study. Busby, J., McMenamin ...
https://pure.qub.ac.uk/en/persons/andrew-spence
Medical Science Monitor | The evaluation of esophageal stenting complications in palliative treatment of dysphagia related to...Medical Science Monitor | The evaluation of esophageal stenting complications in palliative treatment of dysphagia related to...
The aim of this study was to evaluate the safety and efficacy of implantation of self-expandable esophageal stents in ... In patients with neoplastic esophageal stenosis, stenting with coated, self-expandable nitinol prostheses is a safe, effective ... endoscopic and non-endoscopic methods are applied to reduce dysphagia in patients with neoplastic esophageal obstruction. ... palliative treatment of dysphagia related to esophageal cancer.Material/Methods:A total number of 46 patients (41 males and 5 ...
https://medscimonit.com/abstract/index/idArt/882739
Xatmep - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWikiXatmep - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
Breast Neoplasms. *Esophageal Neoplasms. *Leukemia. *Lung Neoplasms. *Mycosis Fungoides. *Osteosarcoma. *Psoriasis. *Stomach ...
https://www.rxwiki.com/xatmep
Gastroenterology and Hepatology - Research output - Mayo Clinic
Occurrence of IgG4 in Esophageal Lichen Planus. Podboy, A. J., Alexander, J. A., Smyrk, T. C., Halland, M., Ravi, K., Geno, D. ... Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma. Ravi, K., Codipilly, D. ... Impact of Coronavirus Disease 2019 on the Diagnosis and Therapy for Barretts Esophagus and Esophageal Cancer in the United ...
https://mayoclinic.pure.elsevier.com/en/organisations/gastroenterology-and-hepatology/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Fshortsurvey&page=1&ordering=type&descending=false
WHO EMRO | Metastatic involvement of draining paratracheal lymph nodes in hypopharyngeal carcinoma: a clinicopathological study...
Role of surgery in the management of postcricoid and oesophageal neoplasms. Annals of otology, rhinology and laryngology, 1972 ... emphasized the importance of removing these nodes when attempting radical resection of pharyngo-oesophageal neoplasms and ... Hiroto I. Hypopharyngeo-oesophageal cancer: its surgical treatment. Krume medical journal, 1963, 10:162-72. ... Hiroto I. Anatomical and pathological studies related to neoplasms of the laryngopharynx. Proceedings of the 9th International ...
http://www.emro.who.int/emhj-volume-3-1997/volume-3-issue-1/article7.html
Pro-inflammatory prostaglandins and progression of colorectal cancer<...
N2 - Chronic inflammation is a risk factor for several gastrointestinal malignancies, including esophageal, gastric, hepatic, ... Colorectal Neoplasms Medicine & Life Sciences 84% * Anti-Inflammatory Agents Medicine & Life Sciences 78% ... AB - Chronic inflammation is a risk factor for several gastrointestinal malignancies, including esophageal, gastric, hepatic, ... Chronic inflammation is a risk factor for several gastrointestinal malignancies, including esophageal, gastric, hepatic, ...
https://asu.pure.elsevier.com/en/publications/pro-inflammatory-prostaglandins-and-progression-of-colorectal-can
Safety and histologic outcomes of endoscopic submucosal dissection with a novel articulating knife for esophageal neoplasia -...
Clutch cutter is a safe device for performing endoscopic submucosal dissection of superficial esophageal neoplasms: a western ... Endoscopic submucosal dissection for early esophageal neoplasms using the stag beetle knife. ... Esophageal cancer practice guidelines 2017 edited by the Japan Esophageal Society: part 1. ... to determine its safety and efficacy for large esophageal neoplasms in comparison with EMR. ...
https://www.giejournal.org/article/S0016-5107
HuGE Navigator|Genopedia|PHGKBHuGE Navigator|Genopedia|PHGKB
Esophageal Neoplasms 1 0 Note: The number of publications displayed in this table will differ from the number displayed in the ...
https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=GKAP1&geneID=80318&typeSubmit=GO&check=y&typeOption=gene&which=2&pubOrderType=pubD
Clinical and psychometric validation of an EORTC questionnaire module, the EORTC QLQ-OES18, to assess quality of life in...Clinical and psychometric validation of an EORTC questionnaire module, the EORTC QLQ-OES18, to assess quality of life in...
Esophageal Neoplasms Medicine & Life Sciences 100% * Psychometrics Medicine & Life Sciences 91% * Organizations Medicine & Life ... questionnaire module to assess QOL in oesophageal cancer. The oesophageal module the QLQ-OES24 and core questionnaire, the ... questionnaire module to assess QOL in oesophageal cancer. The oesophageal module the QLQ-OES24 and core questionnaire, the ... questionnaire module to assess QOL in oesophageal cancer. The oesophageal module the QLQ-OES24 and core questionnaire, the ...
https://abdn.pure.elsevier.com/en/publications/clinical-and-psychometric-validation-of-an-eortc-questionnaire-mo
Research Labs and Institutes | Johns Hopkins MedicineResearch Labs and Institutes | Johns Hopkins Medicine
He performed several groundbreaking genomic, epigenomic and bioinformatic studies of esophageal and colonic neoplasms, shifting ...
https://www.hopkinsmedicine.org/research/research_lab_results.html?query=molecular%20genetics&pagesize=10&page=2
General Surgery Residency Program | Spartanburg RegionalGeneral Surgery Residency Program | Spartanburg Regional
Inpatient experience focuses on lung, esophageal, hepatic and pancreatic neoplasms as well as management of complicated ... Outpatient experience focuses on both benign and malignant breast disease and the management of endocrine neoplasms and ...
https://www.spartanburgregional.com/medical-education/general-surgery-residency/what-to-expect
Systematic Review and Meta-analysis: Use of Statins Is Associated with a Reduced Incidence of Oesophageal Adenocarcinoma |...Systematic Review and Meta-analysis: Use of Statins Is Associated with a Reduced Incidence of Oesophageal Adenocarcinoma |...
... "oesophageal neoplasm", "Barretts oesophagus", "oesophageal adenocarcinoma", "statin", and "hydroxymethylglutaryl-CoA reductase ... The primary analysis examined the association of statin and the incidence of oesophageal carcinoma as well as oesophageal ... oesophageal adenoncarcinoma or high-grade dysplasia, or oesophageal cancer), and provision of hazard ratio (HR), odds ratio (OR ... Oesophageal carcinoma (OC) affects 450,000 people worldwide and is the sixth leading cause of cancer-related mortality in the ...
https://link.springer.com/article/10.1007/s12029-017-9983-0
Red and processed meat consumption and the risk of esophageal and gastric cancer subtypes in The Netherlands Cohort Study<...
keywords = "cohort studies, esophageal neoplasms, processed meat, red meat, stomach neoplasms",. author = "Keszei, {A. P.} and ... After 16.3 years of follow-up, 107 esophageal squamous cell carcinomas, 145 esophageal adenocarcinomas, 163 gastric cardia ... After 16.3 years of follow-up, 107 esophageal squamous cell carcinomas, 145 esophageal adenocarcinomas, 163 gastric cardia ... After 16.3 years of follow-up, 107 esophageal squamous cell carcinomas, 145 esophageal adenocarcinomas, 163 gastric cardia ...
https://cris.maastrichtuniversity.nl/en/publications/red-and-processed-meat-consumption-and-the-risk-of-esophageal-and
Three-Year Survival after Lymphadenectomy for Residual Lymph Node Metastasis of Esophageal Cancer with Invasion into the...
Dive into the research topics of Three-Year Survival after Lymphadenectomy for Residual Lymph Node Metastasis of Esophageal ... Three-Year Survival after Lymphadenectomy for Residual Lymph Node Metastasis of Esophageal Cancer with Invasion into the ...
https://kyushu-u.pure.elsevier.com/en/publications/three-year-survival-after-lymphadenectomy-for-residual-lymph-node/fingerprints/
Emerging Patterns and Current Trends of AIDS Defining and Non-AIDS Defining Malignancies in HIV Infected Individuals from a...Emerging Patterns and Current Trends of AIDS Defining and Non-AIDS Defining Malignancies in HIV Infected Individuals from a...
... of oesophageal adenocarcinoma, pancreatic cystic neoplasm and hepatocellular carcinoma. ... There was 1 case of metastasis with an unknown primary and 1 case of an ocular surface squamous neoplasm. ... Diagnosed to have cystic pancreatic neoplasm at another centre and referred for treatment. ...
https://www.researchsquare.com/article/rs-665698/v1
Cancers | Free Full-Text | The Role of Magnetic Resonance Imaging in the Management of Esophageal CancerCancers | Free Full-Text | The Role of Magnetic Resonance Imaging in the Management of Esophageal Cancer
... with good depiction of the esophageal wall and the esophagogastric junction. Various sequences of MRI have shown good ... Esophageal cancer (EC) is the eighth more frequent cancer worldwide, with a poor prognosis. Initial staging is critical to ... Quint, L.E.; Glazer, G.M.; Orringer, M.B. Esophageal Imaging by MR and CT: Study of Normal Anatomy and Neoplasms. Radiology ... Figure 2. Initial staging for a 77-year-old man with T3N1M0 esophageal adenocarcinoma. (A) Esophagram shows esophageal tumor of ...
https://www.mdpi.com/2072-6694/14/5/1141/htm
Portal Regional da BVSPortal Regional da BVS
Brachytherapy, Head and Neck Neoplasms, Breast Neoplasms, Lung Neoplasms, Esophageal Neoplasms, Genital Neoplasms, Female, Skin ... Breast Neoplasms, 50233, Uterine Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Radiation Oncology, Radiotherapy, ... Urologic Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Medical Oncology, Gynecology, Urology, General Surgery ... Neoplasms, Men's Health, Testicular Neoplasms, Germinoma, Kidney Neoplasms, Nephrology, Urology, Andrology, Diagnostic ...
https://bvsalud.org/en/direve/?q=ginecologia+OR+neonatologia&filter=descriptor:Urology+AND+descriptor:General+Surgery
Squamous Cell CarcCarcinomaAdenocarcinomaCancerEsophagusVaricesRecurrencePancreaticBenignSurvivalDiagnosisDysphagiaNeoplasticMalignant oesophagealPatientsComplicationsEndoscopicDissectionResectionIncidenceColonicCancersLeiomyomaTumoursEndoscopyOesophagusRefluxGastrointestinal NeoplasmsCancersStomachDysphagiaResectionEndoscopicEpithelialDiseasesTumorsRadiotherapyESCCStricturesSquamous cell neoplasmsStrictureBenign and malignant neoplasmsPrimary
Squamous Cell Carc13
  • No difference was noted between squamous cell carcinoma and esophageal adenocarcinoma overall survival curves. (scielo.br)
  • Mean survival for squamous cell carcinoma (SCC) is 13.95±SD 11.2 months and for esophageal adenocarcinoma (EA) is 13.22±SD 10.23 months 4 4. (scielo.br)
  • Tustumi F, Kimura C, Takeda FR, Sallum RAA, RibeiroJr U, Cecconello I. Esophageal carcinoma: Is Squamous Cell Carcinoma different disease compared to adenocarcinoma? (scielo.br)
  • Processed as well as red meat intake was positively associated with esophageal squamous cell carcinoma in men. (maastrichtuniversity.nl)
  • Our findings suggest that red and processed meat consumption is associated with increased risk of esophageal squamous cell carcinoma in men but not with cancers of other esophageal and gastric subtypes. (maastrichtuniversity.nl)
  • The incidence of esophageal adenocarcinoma in the United States has risen rapidly over the last 30 years, whereas the incidence of esophageal squamous cell carcinoma has fallen dramatically. (cdc.gov)
  • Within the United States, Asian-Americans as a whole, have low rates of esophageal adenocarcinoma and higher rates of squamous cell carcinoma. (cdc.gov)
  • We identified all cases of esophageal adenocarcinoma and squamous cell carcinoma from the California Cancer Registry 1988–2004, including 955 cases among 6 different Asian ethnicities. (cdc.gov)
  • Rates of esophageal squamous cell carcinoma varied substantially among different Asian ethnic groups, but squamous cell carcinoma was much more common than adenocarcinoma in both foreign-born and US-born Asian-Americans. (cdc.gov)
  • The purpose of this study was to investigate the predictive value of FDG PET performed early during CRT (on day 21) in a population of patients with oesophageal squamous cell carcinoma.MethodsIncluded in this prospective study were 57 patients with a histological diagnosis of squamous cell carcinoma of the oesophagus. (springernature.com)
  • Colorectal Cancer , Esophageal Cancer , Cutaneous Squamous Cell Carcinoma , and Total Joint Replacement Rehabilitation . (medscape.com)
  • risk of esophageal squamous cell carcinoma. (who.int)
  • PMID:18786442 mutations and the risk of esophageal squamous cell carcinoma. (who.int)
Carcinoma8
  • Oesophageal carcinoma (OC) affects 450,000 people worldwide and is the sixth leading cause of cancer-related mortality in the world [ 1 ]. (springer.com)
  • Materials and Methods: The standardized uptake values and the volumetric parameters (metabolic tumor value and total lesion glycolysis) were determined by 18F-FDG-PET/CT to identify RD in 39 patients before and after nCRT for esophageal carcinoma. (bvsalud.org)
  • Potentially-malignant neoplasms include carcinoma in situ . (wikipedia.org)
  • [12] [13] Some neoplasms do not form a tumor - these include leukemia and most forms of carcinoma in situ . (wikipedia.org)
  • Introduction: The development of oesophageal carcinoma has been attributed to various environmental factors and its incidence varies regionally. (bvsalud.org)
  • EBV-LMPI expression in tumour cells of 10 of 26 cases of oesophageal carcinoma may also be of value in diagnosis and pathogenesis. (bvsalud.org)
  • PurposeFDG PET has been suggested to have predictive value in the prognosis of oesophageal carcinoma. (springernature.com)
  • 4. History of malignant neoplasms within 5 years prior to screening, except for adequately treated basal cell, squamous cell skin cancer, or any in situ carcinoma. (who.int)
Adenocarcinoma11
  • Statin use is associated with a significantly lower incidence of oesophageal adenocarcinoma. (springer.com)
  • In the mid-20th century, adenocarcinoma made up less than 10% of all esophageal cancer cases in the United States. (cdc.gov)
  • Today, adenocarcinoma comprises the majority of esophageal cancer cases in the United States. (cdc.gov)
  • The increased rate of esophageal adenocarcinoma has been particularly striking among White men. (cdc.gov)
  • In contrast, the rates of esophageal adenocarcinoma have remained relatively stable among Asian-Americans during this same time period. (cdc.gov)
  • Asian-Americans continue to have among the lowest annual rates of esophageal adenocarcinoma at 0.7 per 100,000, compared with 4.2 per 100,000 for Caucasians. (cdc.gov)
  • SCC continues to be the dominant form of esophageal cancer throughout Asia despite variation in incidence of esophageal SCC and adenocarcinoma from country to country. (cdc.gov)
  • To better understand the relative influence of genetics and environment on esophageal cancer incidence among Asian-Americans, we investigated the contemporary incidence patterns of esophageal adenocarcinoma and SCC among different Asian-American ethnicities using data from the California Cancer Registry (CCR) enhanced with the ability to examine trends by nativity (country of birth). (cdc.gov)
  • This guideline covers monitoring, treatment and follow-up for people aged 18 and over with Barrett's oesophagus and stage 1 oesophageal adenocarcinoma. (bvsalud.org)
  • The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation. (icr.ac.uk)
  • Background Limited studies examine the immune landscape in Esophageal Adenocarcinoma (EAC). (icr.ac.uk)
Cancer49
  • Oesophageal cancer is endemic in some regions of the Islamic Republic of Iran and efforts have been made to find factors that play a role in its prognosis. (who.int)
  • Early esophageal cancer usually does not cause symptoms. (medlineplus.gov)
  • You're at greater risk for getting esophageal cancer if you smoke, drink heavily, or have acid reflux . (medlineplus.gov)
  • Your doctor uses imaging tests and a biopsy to diagnose esophageal cancer. (medlineplus.gov)
  • Can Esophageal Cancer Be Found Early? (medlineplus.gov)
  • What's New in Esophageal Cancer Research? (medlineplus.gov)
  • The aim of this study was to investigate HRQL in patients alive at least 1 year after surgical resection for esophageal cancer using validated European Organisation for Research and Treatment of Cancer (EORTC) quality of life (QOL) questionnaires (QLQ). (nih.gov)
  • Patients completed general (QLQ-C30) and esophageal cancer-specific (QLQ-OES18, OG25) questionnaires. (nih.gov)
  • A case-control study of esophageal cancer. (cdc.gov)
  • Results are reported from a nested case-control study of 60 esophageal cancer deaths among 46,384 automobile manufacturing workers potentially exposed to metalworking fluid s (MWF) in machining and grinding operations. (cdc.gov)
  • RESULTS: Esophageal cancer was found to be significantly associated with exposure to both soluble and synthetic MWF in grinding operations. (cdc.gov)
  • Those with 12 or more years exposure to soluble MWF in grinding operations experienced a 9.3-fold relative risk of esophageal cancer mortality (95% CI = 2.1-42.1). (cdc.gov)
  • Frequency of esophageal stenosis after simultaneous modulated accelerated radiation therapy and chemotherapy for head and neck cancer. (medscape.com)
  • Late esophageal toxicity after radiation therapy for head and neck cancer. (medscape.com)
  • Despite recent advances in diagnosis and treatment, esophageal cancer still has high mortality. (scielo.br)
  • Assess prognostic variables in esophageal cancer patients. (scielo.br)
  • Retrospective review of all patients with esophageal cancer in an oncology referral center. (scielo.br)
  • Coral RV, Bigolin AV, Coral RP, Hartmann A, Dranka C, Roehe AV. Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best lymph node classification for esophageal cancer? (scielo.br)
  • Standardized clinical pathways for esophagectomy are not a reality in Brazil, even with a high prevalence of esophageal cancer and achalasia. (scielo.br)
  • Impact of minimally invasive surgery in the treatment of esophageal cancer. (scielo.br)
  • Background: Esophageal cancer is the seventh-most frequent cause of cancer-related deaths and it is usually diagnosed at an inoperable stage. (medscimonit.com)
  • The aim of this study was to evaluate the safety and efficacy of implantation of self-expandable esophageal stents in palliative treatment of dysphagia related to esophageal cancer. (medscimonit.com)
  • Chronic inflammation is a risk factor for several gastrointestinal malignancies, including esophageal, gastric, hepatic, pancreatic and colorectal cancer. (elsevier.com)
  • This study defined measurement properties and the clinical validity of the European Organisation for Research and Treatment of Cancer (EORTC) questionnaire module to assess QOL in oesophageal cancer. (elsevier.com)
  • It is recommended for use with the core questionnaire, the QLQ-C30, to assess QOL in patients with oesophageal cancer. (elsevier.com)
  • We performed a systematic review and meta-analysis of the association between statin use and the development of oesophageal cancer. (springer.com)
  • Multiple databases were searched for studies reporting the association of statin use and oesophageal cancer. (springer.com)
  • Prospective data on red and processed meat in relation to risk of subtypes of esophageal and gastric cancer are scarce. (maastrichtuniversity.nl)
  • We present analyses of association between red and processed meat and the risk of esophageal and gastric cancer subtypes within The Netherlands Cohort Study on Diet and Cancer. (maastrichtuniversity.nl)
  • Esophageal cancer (EC) is the eighth most frequent cancer worldwide, with a poor prognosis. (mdpi.com)
  • The relative influence of ethnicity and environment on the incidence of esophageal cancer in this population is unknown. (cdc.gov)
  • These results provide better insight into the genetic and environmental factors affecting the changing incidence of esophageal cancer histologies in the United States and Asia. (cdc.gov)
  • An estimated 17,000 cases of esophageal cancer were diagnosed in the United States in 2013. (cdc.gov)
  • The overall trends of esophageal cancer incidence in Asia have been different from those in the United States. (cdc.gov)
  • Abstract Objective: To evaluate the maximum and mean standardized uptake values, together with the metabolic tumor value and the total lesion glycolysis, at the primary tumor site, as determined by 18F-fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG-PET/CT), performed before and after neoadjuvant chemoradiotherapy (nCRT), as predictors of residual disease (RD) in patients with esophageal cancer. (bvsalud.org)
  • Considering the presence of visually detectable uptake (higher than the background level) at the primary tumor site after nCRT as a positive result, we achieved a sensitivity of 94% and a specificity of 48% for the detection of RD. Conclusion: The use of 18F-FDG-PET/CT can facilitate the detection of RD after nCRT in patients with esophageal cancer. (bvsalud.org)
  • A neoplasm can be benign , potentially malignant, or malignant ( cancer ). (wikipedia.org)
  • Malignant neoplasms are commonly called cancer. (wikipedia.org)
  • Secondary neoplasm refers to any of a class of cancerous tumor that is either a metastatic offshoot of a primary tumor, or an apparently unrelated tumor that increases in frequency following certain cancer treatments such as chemotherapy or radiotherapy . (wikipedia.org)
  • Rarely there can be a metastatic neoplasm with no known site of the primary cancer and this is classed as a cancer of unknown primary origin . (wikipedia.org)
  • Platinum-based neoadjuvant therapy is the standard treatment for esophageal cancer (EC). (elsevier.com)
  • This study aimed to determine the impact of preoperative staging on the treatment of clinical T2N0 (cT2N0) esophageal cancer patients undergoing esophagectomy. (elsevier.com)
  • Seventy-four oesophageal resections were performed with a yearly average resection rate of only 5.6%.Conclusions: SCC is still the most prevalent oesophageal cancer (OC) without an increase in the ratio of AC to SCC. (bvsalud.org)
  • the diagnosis of oesophageal cancer in its premalignant stage would improve the survival. (bvsalud.org)
  • A prospective comparison of multidisciplinary treatment of oesophageal cancer with curative intent in a UK cancer network. (ox.ac.uk)
  • AIMS: Combined modality therapy (with chemotherapy+/-radiotherapy) has become a standard treatment for locally advanced oesophageal cancer. (ox.ac.uk)
  • The changes in SUVmax, TV40, TVp, TLG40 and TLGp between PET1 and PET2 had no relationship to patient outcome at 3 months or 1 year.ConclusionThis prospective, multicentre study performed in a selected population of patients with oesophageal squamous cell cancer demonstrates that the parameters derived from baseline PET1 are good predictors of response to CRT. (springernature.com)
  • According to estimates from the World Health Organization, 8.3 million people worldwide died from cancer and other neoplasms in 2008-about 14% of all deaths. (avalonecon.com)
  • EUS has an integral role in the diagnosis of pancreatic cancer given its high sensitivity for detecting pancreatic neoplasms and the access it affords to perform fine needle aspiration (FNA) of the suspected lesions. (abdominalkey.com)
Esophagus1
  • Typical appearance of esophageal leiomyoma (pathology proven), a benign smooth muscle neoplasm which may occur in the esophagus. (radiopaedia.org)
Varices3
  • Upper gastrointestinal endoscopy detected esophageal and duodenal varices. (go.jp)
  • Univariate analysis showed Aloxistatin datasheet the correlations of the diameters with the presence of esophageal varices (Table 2). (micrornaarray.com)
  • 2. History of cirrhosis and/or hepatic decompensation, including evidence of portal hypertension (e.g. low platelet count, splenomegaly, ascites, history of hepatic encephalopathy, esophageal varices, or variceal bleeding). (who.int)
Recurrence2
  • Smith PM, Kerr GD, Cockel R. A comparison of omeprazole and ranitidine in the prevention of recurrence of benign esophageal stricture. (medscape.com)
  • Prevention of recurrence of oesophageal stricture, a comparison of lansoprazole and high-dose ranitidine. (medscape.com)
Pancreatic3
  • Inpatient experience focuses on lung, esophageal, hepatic and pancreatic neoplasms as well as management of complicated pancreatitis. (spartanburgregional.com)
  • The hand-assisted laparoscopic approach to resection of pancreatic mucinous cystic neoplasms: An underused technique? (wustl.edu)
  • Interestingly, the incidence of pancreatic endocrine neoplasms increased over the same time periods by 106% in men and 125% in women. (abdominalkey.com)
Benign5
  • Endoscopic management of benign esophageal strictures. (medscape.com)
  • Outpatient experience focuses on both benign and malignant breast disease and the management of endocrine neoplasms and melanoma. (spartanburgregional.com)
  • benign neoplasms , in situ neoplasms , malignant neoplasms , and neoplasms of uncertain or unknown behavior. (wikipedia.org)
  • Leiomyoma is the most common benign oesophageal tumour. (biomedcentral.com)
  • At experienced centres, laparoscopic transhiatal enucleation of lower oesophageal leiomyomas and other benign tumours with a combination of intraoperative oesophagoscopy is a safe, fast and effective operation. (biomedcentral.com)
Survival1
  • We compared the mortality, procedure-related complications, hospital stay, intervention time, improvement of dysphagia and survival time between esophageal stent and surgery. (who.int)
Diagnosis1
  • The differential diagnosis was focused on heart failure, lung disease, and occult neoplasm. (springeropen.com)
Dysphagia3
  • Oesophagitis is as important as oesophageal stricture diameter in determining dysphagia. (medscape.com)
  • In palliative treatment, endoscopic and non-endoscopic methods are applied to reduce dysphagia in patients with neoplastic esophageal obstruction. (medscimonit.com)
  • Conclusions: In patients with neoplastic esophageal stenosis, stenting with coated, self-expandable nitinol prostheses is a safe, effective and fast method of palliative dysphagia treatment. (medscimonit.com)
Neoplastic1
  • In modern English, tumor is used as a synonym for neoplasm (a solid or fluid-filled cystic lesion that may or may not be formed by an abnormal growth of neoplastic cells) that appears enlarged in size. (wikipedia.org)
Malignant oesophageal2
  • Predictor of massive bleeding following stent placement for malignant oesophageal stricture/fistulae: a multicentre study. (medscape.com)
  • Methods: A retrospective review of histopathological reports on pre-malignant and malignant oesophageal lesions over three time periods (TP), namely: 2003-4 (TP1), 2008-9 (TP2) and 2013-14 (TP3) was carried out at Inkosi Albert Luthuli Central Hospital, Durban, South Africa.Results: A total of 1341 specimen reports were retrieved. (bvsalud.org)
Patients5
  • Long-term PPI therapy (almost indefinitely) is extremely important in patients with esophageal stricture. (medscape.com)
  • The oesophageal module the QLQ-OES24 and core questionnaire, the Quality of Life-Core 30 questionnaire (QLQ-C30) was administered patients undergoing treatment with curative (n = 267) or palliative intent (n = 224) and second assessments performed 3 months or 3 weeks later respectively. (elsevier.com)
  • There were twenty patients who underwent esophageal stent and twenty-three patients underwent surgical treatment. (who.int)
  • Esophageal leiomyoma: radiologic findings in 12 patients. (radiopaedia.org)
  • We examined the patients' background (tumor location, macroscopic type, tumor size, histological type, and depth of invasion) and treatment outcomes (procedure duration, en bloc resection rate, R0 resection rate, and adverse events). (bvsalud.org)
Complications1
  • In the esophageal stent group, the complications were severe chest pain 10 per cent (2/20), stent displacement 10.52 per cent (2/19), stent obstruction from food impaction 15.78 per cent (3/19) and tumor overgrowth leading to stent obstruction 5.26 per cent (1/19). (who.int)
Endoscopic3
  • Predictors of postoperative stricture after esophageal endoscopic submucosal dissection for superficial squamous cell neoplasms. (medscape.com)
  • Endoscopic management of difficult or recurrent esophageal strictures. (medscape.com)
  • We aimed to evaluate a novel endoscopic articulating knife used with ESD (ESD-AR) to determine its safety and efficacy for large esophageal neoplasms in comparison with EMR. (giejournal.org)
Dissection1
  • Som [4] emphasized the importance of removing these nodes when attempting radical resection of pharyngo-oesophageal neoplasms and advocated dissection of the lymph nodes lying above the innominate vein in the superior mediastinum. (who.int)
Resection1
  • CONCLUSIONS: A high en bloc resection rate without perforation was achieved with ESD for lesions at anastomotic sites. (bvsalud.org)
Incidence1
  • A decreasing incidence of oesophageal SCC in SA has been suggested. (bvsalud.org)
Colonic1
  • He performed several groundbreaking genomic, epigenomic and bioinformatic studies of esophageal and colonic neoplasms, shifting the GI research paradigm toward genome-wide approaches. (hopkinsmedicine.org)
Cancers2
  • Les cancers de l' oesophage en 1984 : 135 questions, recueil des communications du Premier Congrès international polydisciplinaire, Paris, 17, 18, 19 mai 1984 / sous la direction de R. Giuli. (who.int)
  • [7] Malignant neoplasms are also simply known as cancers and are the focus of oncology . (wikipedia.org)
Leiomyoma2
  • We report a rare case of a duplicated lower-third oesophageal leiomyoma, which was completely removed via the laparoscopic transhiatal approach. (biomedcentral.com)
  • Niknejad M, Esophageal leiomyoma. (radiopaedia.org)
Tumours1
  • Histological typing of gastric and oesophageal tumours / H. Watanabe, J. R. Jass and L. H. Sobin, in collaboration with pathologists in 8 countries. (who.int)
Endoscopy6
  • With negative biopsy and no tumor on endoscopy, a neoplasm becomes highly unlikely. (medscape.com)
  • Lugol's iodine dye indicates the presence of unsuspected early oesophageal cancers during endoscopy at which such cancers fail to show the characteristic black colour change. (elsevier.com)
  • Lugol's iodine augmented the information gained about the oesophageal mucosa during endoscopy. (elsevier.com)
  • We recommend the routine use of Lugol's iodine-enhanced endoscopy for surveillance of all 'at risk' oesophageal cases. (elsevier.com)
  • These outcomes incited us to apply this treatment in the endoscopy field, and we zeroed in on oral mucosal epithelial cells as the cell source rather than esophageal epithelial cells. (scitechnol.com)
  • With regards to gather the esophageal mucosa for esophageal tissue designing, there is consistently a danger of hole on the grounds that the esophageal mucosa is really eliminated by endoscopy [ 3 ]. (scitechnol.com)
Oesophagus5
  • Of the 344 neoplasms in lower oesophagus , 128 were adenocarcinomas and 182 were squamous cell carcinomas. (thefreedictionary.com)
  • Oesophageal stricture or spasm, neoplasms in the oesophagus and head-neck area, pathologies affecting the oral cavity. (deutera.com)
  • An X-ray with barium is carried out to identify the cause of oropharyngeal dysphagia (a fluoroscopic examination of the swallowing process) and conditions resulting in oesophageal motility, such as Zenker's diverticulum, achalasia, jackhammer oesophagus and hiatus hernia. (deutera.com)
  • The major drawback of stenting tumours in the lower oesophagus or oesophagogastric junction (OGJ), is the associated gastro-oesophageal reflux (GOR) resulting from the stent crossing the lower oesophageal sphincter and essentially negating the native anti-reflux mechanism. (clincosm.com)
  • Theoretically, oesophageal stents containing an anti-reflux valve should provide a physical barrier to prevent gastric content (which may be acidic or non-acidic) refluxing into the oesophagus, but whether this results in decreased rates of GOR in reality is somewhat controversial. (clincosm.com)
Reflux9
  • Peptic esophageal strictures are sequelae of gastroesophageal reflux -induced esophagitis, and they usually originate at the squamocolumnar junction and average 1-4 cm in length. (medscape.com)
  • Dysfunctional lower esophageal sphincter: Mean LES pressures are lower in patients with peptic strictures compared with healthy controls or patients with milder degrees of reflux disease. (medscape.com)
  • Hiatal hernias are found in 10-15% of the general population, 42% of patients with reflux symptoms and no esophagitis, 63% of patients with esophagitis, and 85% of patients with peptic esophageal strictures. (medscape.com)
  • BE is strongly associated with prolonged gastro-esophageal reflux of gastric and bile acids (1, 3, 4). (irb.hr)
  • Animals underwent specific surgical procedures to produce esophageal reflux of pure duodenal contents, mixed gastroduodenal, or bland intestinal contents. (elsevier.com)
  • Ambulatory monitoring of oesophageal pH with or without a study of impedance can be used to exclude gastroesophageal reflux disease. (deutera.com)
  • Reflux will be measured using patient questionnaires about reflux, and other quality of life parameters, and will also be objectively measured using oesophageal scintigraphy, which has not been used in previous similar trials. (clincosm.com)
  • To date, a number of trials have compared a range of anti-reflux oesophageal stents to conventional oesophageal stents and although there have been some conflicting results, a systematic review and meta-analysis in 2019 concludes that GOR is not significantly reduced by the use of anti-reflux stents. (clincosm.com)
  • Eradication of H pylori infection (a) does not cause gastro-oesophageal reflux disease (GORD) or exacerbate GORD, and (b) may prevent peptic ulcer in patients who are naïve users of non-steroidal antiinflammatory drugs (NSAIDs). (elsevier.com)
Gastrointestinal Neoplasms1
  • Classify here works on gastrointestinal neoplasms. (nih.gov)
Cancers3
  • Recent series reported increasing incidence of esophageal and cardial cancers with prognosis still severe in spite of surgical progress. (elsevier.com)
  • The vast majority of esophageal cancers in China, India and Iran are esophageal squamous cell carcinomas (ESCC). (elsevier.com)
  • Early response assessment using PET imaging can be incorporated into future studies to identify more effective new regimens for esophageal and GEJ cancers. (medpagetoday.com)
Stomach9
  • 20. [Stomach and esophageal neoplasm. (nih.gov)
  • 3) Oxyntic gland neoplasm of the stomach: expanding the spectrum and proposal of terminology. (todai-shoukakan.com)
  • Submit your Twitter account related to Stomach Neoplasms to be featured! (novusbio.com)
  • Submit your blog on Stomach Neoplasms to be featured! (novusbio.com)
  • The study of Stomach Neoplasms has been mentioned in research publications which can be found using our bioinformatics tool below. (novusbio.com)
  • These pathways complement our catalog of research reagents for the study of Stomach Neoplasms including antibodies and ELISA kits against TP53, CARCINOEMBRYONIC ANTIGEN, VEGFA, CEACAM7, CEACAM5. (novusbio.com)
  • Explore more on Stomach Neoplasms below! (novusbio.com)
  • We have 5399 products for the study of Stomach Neoplasms that can be applied to Chromatin Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits. (novusbio.com)
  • Dysphagia is the medical term to indicate problems with swallowing, or rather difficulty in the passage of food and beverages from the oral cavity to the stomach , due to structural anomaly or oesophageal motility disorders. (deutera.com)
Dysphagia1
  • The most common and debilitating symptom of advanced oesophageal malignancy is progressive dysphagia, which can be addressed by the endoscopic placement of self-expanding metal stents. (clincosm.com)
Resection4
  • The treatment for symptomatic lesions is surgical resection, which often requires esophageal replacement because of the diffuse nature of the disease. (medscape.com)
  • Resection of early esophageal neoplasms: The pendulum swings from surgical to endoscopic management. (wjgnet.com)
  • Som [4] emphasized the importance of removing these nodes when attempting radical resection of pharyngo-oesophageal neoplasms and advocated dissection of the lymph nodes lying above the innominate vein in the superior mediastinum. (who.int)
  • We attempted to investigate the diagnostic value of a transendoscopic balloon-tipped miniature ultrasonic endoprobe for small esophageal leiomyomas derived from MM. We resected 7 small esophageal leiomyomas derived from MM by endoscopic mucosal resection (EMR), all of which were diagnosed by a balloon-tipped endoprobe. (elsevier.com)
Endoscopic9
  • The etiology of esophageal stricture can usually be identified using radiologic and endoscopic modalities and can be confirmed by endoscopic visualization and tissue biopsy. (medscape.com)
  • Fortunately, most benign esophageal strictures are amenable to pharmacologic, endoscopic, and/or surgical interventions. (medscape.com)
  • 4) Steroid injection and polyglycolic acid shielding to prevent stricture after esophageal endoscopic submucosal dissection: a retrospective comparative analysis (with video). (todai-shoukakan.com)
  • Esophageal injury is the significant entanglement happening after generous endoscopic submucosal analyzation (ESD) of shallow esophageal neoplasms. (scitechnol.com)
  • To forestall post-ESD esophageal injury, ensuing endoscopic inflatable widening (EBD) is frequently required, yet there is a danger of hole after EBD. (scitechnol.com)
  • Yamaguchi announced the requirement for a normal of 15.6 meetings of endoscopic inflatable widening in instances of 2/3-circumferential esophageal ESD, and a normal of 32.7 meetings in full-circumferential esophageal ESD. (scitechnol.com)
  • To forestall esophageal injury, we began research on the endoscopic transplantation of tissue-designed autologous oral mucosal epithelial cell sheets (OMECS) in 2004 and fostered a treatment for clinical use. (scitechnol.com)
  • Endoscopic ultrasonography can provide an accurate image of esophageal layer structure, providing information on lesion suitability for potential endoscopic therapy. (elsevier.com)
  • Retrograde endoscopic dilatation for difficult caustic esophageal strictures: Feasibility and effectiveness. (academic-accelerator.com)
Epithelial1
  • We carried out reverse phase protein array-based protein expression profiling of seven ESCC-derivedcell lines and a non-neoplastic esophageal epithelial cell line (Het-1A) to identify differentially expressed proteins in ESCC. (elsevier.com)
Diseases2
  • and (3) diseases that disrupt esophageal peristalsis and/or lower esophageal sphincter (LES) function by their effects on esophageal smooth muscle and its innervation. (medscape.com)
  • Many diseases can cause esophageal stricture formation. (medscape.com)
Tumors1
  • In all cases, endosonographic findings by endoprobe were exactly concordant with pathologic finding in determining the tumors depth in the esophageal wall, tissue origin and characteristics, growth pattern, and size. (elsevier.com)
Radiotherapy1
  • Radiotherapy, following oral cavity surgery, patients with structural damage to the muscles in the oesophageal wall. (deutera.com)
ESCC1
  • A total of 50 ESCC tissues and their corresponding normal adjacent esophageal tissue samples were collected. (medscimonit.com)
Strictures7
  • Because peptic strictures account for 70-80% of all cases of esophageal stricture, peptic stricture is the focus of this article. (medscape.com)
  • A study by Ahtaridis et al showed that patients with peptic esophageal strictures had a mean LES pressure of 4.9 mm Hg versus 20 mm Hg in control patients. (medscape.com)
  • Disordered motility resulting in poor esophageal clearance: In the same study, Ahtaridis et al demonstrated that 64% of patients with strictures had motility disorders compared with 32% of patients without strictures. (medscape.com)
  • Patients with peptic esophageal strictures have been demonstrated to have the same acid and pepsin secretion rates as sex-matched and age-matched controls with esophagitis but no stricture formation. (medscape.com)
  • Gastric emptying: No good evidence suggests that delayed emptying plays a role in peptic esophageal strictures. (medscape.com)
  • Background: Impassable caustic esophageal strictures (CES) can be rendered passable through sophisticated dilatation techniques, hence avoiding the esophageal replacement surgery and its complications. (academic-accelerator.com)
  • BACKGROUND Difficult caustic esophageal strictures may need a more sophisticated dilatation technique before referring for esophageal replacement surgery. (academic-accelerator.com)
Squamous cell neoplasms1
  • Lee, Ching-Tai 2018-06-01 00:00:00 BackgroundEndoscopic radiofrequency ablation (RFA) is a rapidly evolving therapeutic modality for early flat esophageal squamous cell neoplasms (ESCNs). (deepdyve.com)
Stricture4
  • A detailed discussion of possible benign and malignant processes associated with esophageal stricture and its management is beyond the scope of this article. (medscape.com)
  • [ 1 ] An LES pressure of less than 8 mm Hg appeared to correlate significantly with the presence of peptic esophageal stricture without any overlap in controls. (medscape.com)
  • The treatment gave good disease control, at the expense of a high oesophageal stricture. (ox.ac.uk)
  • The Effectiveness of Combined Balloon and Bougie Dilatation Technique in Children with Impassable Esophageal Stricture. (academic-accelerator.com)
Benign and malignant neoplasms1
  • Consequently, this article focuses on the more common benign and malignant neoplasms of the GI tract in children, in addition to information gleaned from the relatively sparse literature. (medscape.com)
Primary1
  • Primary gastrointestinal (GI) neoplasms in children are rare. (medscape.com)