Infections with bacteria of the species ESCHERICHIA COLI.
Proteins obtained from ESCHERICHIA COLI.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
A verocytotoxin-producing serogroup belonging to the O subfamily of Escherichia coli which has been shown to cause severe food-borne disease. A strain from this serogroup, serotype H7, which produces SHIGA TOXINS, has been linked to human disease outbreaks resulting from contamination of foods by E. coli O157 from bovine origin.
Strains of ESCHERICHIA COLI with the ability to produce at least one or more of at least two antigenically distinct, usually bacteriophage-mediated cytotoxins: SHIGA TOXIN 1 and SHIGA TOXIN 2. These bacteria can cause severe disease in humans including bloody DIARRHEA and HEMOLYTIC UREMIC SYNDROME.
A syndrome that is associated with microvascular diseases of the KIDNEY, such as RENAL CORTICAL NECROSIS. It is characterized by hemolytic anemia (ANEMIA, HEMOLYTIC); THROMBOCYTOPENIA; and ACUTE RENAL FAILURE.
Inflammation of a serous membrane.
A toxin produced by certain pathogenic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157. It is closely related to SHIGA TOXIN produced by SHIGELLA DYSENTERIAE.
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
Strains of ESCHERICHIA COLI characterized by attaching-and-effacing histopathology. These strains of bacteria intimately adhere to the epithelial cell membrane and show effacement of microvilli. In developed countries they are associated with INFANTILE DIARRHEA and infantile GASTROENTERITIS and, in contrast to ETEC strains, do not produce ENDOTOXINS.
A toxin produced by certain pathogenic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157. It shares 50-60% homology with SHIGA TOXIN and SHIGA TOXIN 1.
A class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS. They include SHIGA TOXIN which is produced by SHIGELLA DYSENTERIAE and a variety of shiga-like toxins that are produced by pathologic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157.
Proteins found in any species of bacterium.
The functional hereditary units of BACTERIA.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
A toxin produced by SHIGELLA DYSENTERIAE. It is the prototype of class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Strains of Escherichia coli that preferentially grow and persist within the urinary tract. They exhibit certain virulence factors and strategies that cause urinary tract infections.
Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A species of gram-negative, rod-shaped bacteria belonging to the K serogroup of ESCHERICHIA COLI. It lives as a harmless inhabitant of the human LARGE INTESTINE and is widely used in medical and GENETIC RESEARCH.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
Thin, filamentous protein structures, including proteinaceous capsular antigens (fimbrial antigens), that mediate adhesion of E. coli to surfaces and play a role in pathogenesis. They have a high affinity for various epithelial cells.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
DIARRHEA occurring in infants from newborn to 24-months old.
Substances that are toxic to the intestinal tract causing vomiting, diarrhea, etc.; most common enterotoxins are produced by bacteria.
Thin, hairlike appendages, 1 to 20 microns in length and often occurring in large numbers, present on the cells of gram-negative bacteria, particularly Enterobacteriaceae and Neisseria. Unlike flagella, they do not possess motility, but being protein (pilin) in nature, they possess antigenic and hemagglutinating properties. They are of medical importance because some fimbriae mediate the attachment of bacteria to cells via adhesins (ADHESINS, BACTERIAL). Bacterial fimbriae refer to common pili, to be distinguished from the preferred use of "pili", which is confined to sex pili (PILI, SEX).
Substances that reduce the growth or reproduction of BACTERIA.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
Proteins that are structural components of bacterial fimbriae (FIMBRIAE, BACTERIAL) or sex pili (PILI, SEX).
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION.
Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.
Infection by parasites of the genus BALANTIDIUM. The presence of Balantidium in the LARGE INTESTINE leads to DIARRHEA; DYSENTERY; and occasionally ULCER.
Diseases of domestic swine and of the wild boar of the genus Sus.
Strains of ESCHERICHIA COLI that produce or contain at least one member of either heat-labile or heat-stable ENTEROTOXINS. The organisms colonize the mucosal surface of the small intestine and elaborate their enterotoxins causing DIARRHEA. They are mainly associated with tropical and developing countries and affect susceptible travelers to those places.
The rate dynamics in chemical or physical systems.
Proteins isolated from the outer membrane of Gram-negative bacteria.
Structures within the nucleus of bacterial cells consisting of or containing DNA, which carry genetic information essential to the cell.
Ribonucleic acid in bacteria having regulatory and catalytic roles as well as involvement in protein synthesis.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Proteins prepared by recombinant DNA technology.
Strains of ESCHERICHIA COLI that are a subgroup of SHIGA-TOXIGENIC ESCHERICHIA COLI. They cause non-bloody and bloody DIARRHEA; HEMOLYTIC UREMIC SYNDROME; and hemorrhagic COLITIS. An important member of this subgroup is ESCHERICHIA COLI O157-H7.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
Viruses whose host is Escherichia coli.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
A genus of protozoa parasitic in the digestive tract of vertebrate or invertebrate hosts. Asexual multiplication is accomplished by transverse binary fission. Its organisms are ovoidal in shape and have a ciliated covering over the entire body.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms.
Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype when another mutant genome, encoding the same mutant phenotype, is introduced into that cell.
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
Use of restriction endonucleases to analyze and generate a physical map of genomes, genes, or other segments of DNA.
Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Elements of limited time intervals, contributing to particular results or situations.
Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3).
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
A parasexual process in BACTERIA; ALGAE; FUNGI; and ciliate EUKARYOTA for achieving exchange of chromosome material during fusion of two cells. In bacteria, this is a uni-directional transfer of genetic material; in protozoa it is a bi-directional exchange. In algae and fungi, it is a form of sexual reproduction, with the union of male and female gametes.
Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms occur in the lower part of the intestine of warm-blooded animals. The species are either nonpathogenic or opportunistic pathogens.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.
The sum of the weight of all the atoms in a molecule.
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1.
Any method used for determining the location of and relative distances between genes on a chromosome.
Vaccines or candidate vaccines used to prevent or treat both enterotoxigenic and enteropathogenic Escherichia coli infections.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
A temperate inducible phage and type species of the genus lambda-like viruses, in the family SIPHOVIRIDAE. Its natural host is E. coli K12. Its VIRION contains linear double-stranded DNA with single-stranded 12-base 5' sticky ends. The DNA circularizes on infection.
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Transport proteins that carry specific substances in the blood or across cell membranes.
A species of gram-negative, rod-shaped bacteria isolated from the intestinal tract of swine, poultry, and man. It may be pathogenic.
Membrane proteins whose primary function is to facilitate the transport of molecules across a biological membrane. Included in this broad category are proteins involved in active transport (BIOLOGICAL TRANSPORT, ACTIVE), facilitated transport and ION CHANNELS.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The transfer of bacterial DNA by phages from an infected bacterium to another bacterium. This also refers to the transfer of genes into eukaryotic cells by viruses. This naturally occurring process is routinely employed as a GENE TRANSFER TECHNIQUE.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept.
Bacteriocins elaborated by strains of Escherichia coli and related species. They are proteins or protein-lipopolysaccharide complexes lethal to other strains of the same species.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1.
A subdiscipline of genetics which deals with the genetic mechanisms and processes of microorganisms.
An infant during the first month after birth.
Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Substances elaborated by bacteria that have antigenic activity.
A family of galactoside hydrolases that hydrolyze compounds with an O-galactosyl linkage. EC 3.2.1.-.
The genetic unit consisting of three structural genes, an operator and a regulatory gene. The regulatory gene controls the synthesis of the three structural genes: BETA-GALACTOSIDASE and beta-galactoside permease (involved with the metabolism of lactose), and beta-thiogalactoside acetyltransferase.
Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.
An error-prone mechanism or set of functions for repairing damaged microbial DNA. SOS functions (a concept reputedly derived from the SOS of the international distress signal) are involved in DNA repair and mutagenesis, in cell division inhibition, in recovery of normal physiological conditions after DNA repair, and possibly in cell death when DNA damage is extensive.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Presence of warmth or heat or a temperature notably higher than an accustomed norm.
The heritable modification of the properties of a competent bacterium by naked DNA from another source. The uptake of naked DNA is a naturally occuring phenomenon in some bacteria. It is often used as a GENE TRANSFER TECHNIQUE.
Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.
The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Genes which regulate or circumscribe the activity of other genes; specifically, genes which code for PROTEINS or RNAs which have GENE EXPRESSION REGULATION functions.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
Multicomponent ribonucleoprotein structures found in the CYTOPLASM of all cells, and in MITOCHONDRIA, and PLASTIDS. They function in PROTEIN BIOSYNTHESIS via GENETIC TRANSLATION.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
The phenomenon by which a temperate phage incorporates itself into the DNA of a bacterial host, establishing a kind of symbiotic relation between PROPHAGE and bacterium which results in the perpetuation of the prophage in all the descendants of the bacterium. Upon induction (VIRUS ACTIVATION) by various agents, such as ultraviolet radiation, the phage is released, which then becomes virulent and lyses the bacterium.
Periplasmic proteins that scavenge or sense diverse nutrients. In the bacterial environment they usually couple to transporters or chemotaxis receptors on the inner bacterial membrane.
Infections with bacteria of the genus CAMPYLOBACTER.
A family of recombinases initially identified in BACTERIA. They catalyze the ATP-driven exchange of DNA strands in GENETIC RECOMBINATION. The product of the reaction consists of a duplex and a displaced single-stranded loop, which has the shape of the letter D and is therefore called a D-loop structure.
The complete absence, or (loosely) the paucity, of gaseous or dissolved elemental oxygen in a given place or environment. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Mutation process that restores the wild-type PHENOTYPE in an organism possessing a mutationally altered GENOTYPE. The second "suppressor" mutation may be on a different gene, on the same gene but located at a distance from the site of the primary mutation, or in extrachromosomal genes (EXTRACHROMOSOMAL INHERITANCE).
The sequential correspondence of nucleotides in one nucleic acid molecule with those of another nucleic acid molecule. Sequence homology is an indication of the genetic relatedness of different organisms and gene function.
Periplasmic proteins that bind MALTOSE and maltodextrin. They take part in the maltose transport system of BACTERIA.
A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.
Biologically active DNA which has been formed by the in vitro joining of segments of DNA from different sources. It includes the recombination joint or edge of a heteroduplex region where two recombining DNA molecules are connected.
A form of gram-negative meningitis that tends to occur in neonates, in association with anatomical abnormalities (which feature communication between the meninges and cutaneous structures) or as OPPORTUNISTIC INFECTIONS in association with IMMUNOLOGIC DEFICIENCY SYNDROMES. In premature neonates the clinical presentation may be limited to ANOREXIA; VOMITING; lethargy; or respiratory distress. Full-term infants may have as additional features FEVER; SEIZURES; and bulging of the anterior fontanelle. (From Menkes, Textbook of Child Neurology, 5th ed, pp398-400)
A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER.
The small RNA molecules, 73-80 nucleotides long, that function during translation (TRANSLATION, GENETIC) to align AMINO ACIDS at the RIBOSOMES in a sequence determined by the mRNA (RNA, MESSENGER). There are about 30 different transfer RNAs. Each recognizes a specific CODON set on the mRNA through its own ANTICODON and as aminoacyl tRNAs (RNA, TRANSFER, AMINO ACYL), each carries a specific amino acid to the ribosome to add to the elongating peptide chains.
A species of gram-negative bacteria in the genus CITROBACTER, family ENTEROBACTERIACEAE. As an important pathogen of laboratory mice, it serves as a model for investigating epithelial hyperproliferation and tumor promotion. It was previously considered a strain of CITROBACTER FREUNDII.
A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.
A protein which is a subunit of RNA polymerase. It effects initiation of specific RNA chains from DNA.
Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
Proteins found in ribosomes. They are believed to have a catalytic function in reconstituting biologically active ribosomal subunits.
Life or metabolic reactions occurring in an environment containing oxygen.
The process by which a DNA molecule is duplicated.
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.
INFLAMMATION of the UDDER in cows.
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.
A plasmid whose presence in the cell, either extrachromosomal or integrated into the BACTERIAL CHROMOSOME, determines the "sex" of the bacterium, host chromosome mobilization, transfer via conjugation (CONJUGATION, GENETIC) of genetic material, and the formation of SEX PILI.
A rather large group of enzymes comprising not only those transferring phosphate but also diphosphate, nucleotidyl residues, and others. These have also been subdivided according to the acceptor group. (From Enzyme Nomenclature, 1992) EC 2.7.
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
Proteins found in the PERIPLASM of organisms with cell walls.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
The genetic complement of a BACTERIA as represented in its DNA.
Measurable quantity of bacteria in an object, organism, or organism compartment.
A species of gram-positive bacteria that is a common soil and water saprophyte.
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants.
A class of plasmids that transfer antibiotic resistance from one bacterium to another by conjugation.
A non-metabolizable galactose analog that induces expression of the LAC OPERON.
The space between the inner and outer membranes of a cell that is shared with the cell wall.
A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
The process of cleaving a chemical compound by the addition of a molecule of water.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.
A set of three nucleotides in a protein coding sequence that specifies individual amino acids or a termination signal (CODON, TERMINATOR). Most codons are universal, but some organisms do not produce the transfer RNAs (RNA, TRANSFER) complementary to all codons. These codons are referred to as unassigned codons (CODONS, NONSENSE).
Glycosphingolipids which contain as their polar head group a trisaccharide (galactose-galactose-glucose) moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in ceramide trihexosidase, is the cause of angiokeratoma corporis diffusum (FABRY DISEASE).
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
The extent to which an enzyme retains its structural conformation or its activity when subjected to storage, isolation, and purification or various other physical or chemical manipulations, including proteolytic enzymes and heat.
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
An essential amino acid that is required for the production of HISTAMINE.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Proteins from BACTERIA and FUNGI that are soluble enough to be secreted to target ERYTHROCYTES and insert into the membrane to form beta-barrel pores. Biosynthesis may be regulated by HEMOLYSIN FACTORS.
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to alpha helices, beta strands (which align to form beta sheets) or other types of coils. This is the first folding level of protein conformation.
Stable carbon atoms that have the same atomic number as the element carbon, but differ in atomic weight. C-13 is a stable carbon isotope.
Cells, usually bacteria or yeast, which have partially lost their cell wall, lost their characteristic shape and become round.
Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
Porins are protein molecules that were originally found in the outer membrane of GRAM-NEGATIVE BACTERIA and that form multi-meric channels for the passive DIFFUSION of WATER; IONS; or other small molecules. Porins are present in bacterial CELL WALLS, as well as in plant, fungal, mammalian and other vertebrate CELL MEMBRANES and MITOCHONDRIAL MEMBRANES.

Protective effect of bactericidal/permeability-increasing protein (rBPI21) in baboon sepsis is related to its antibacterial, not antiendotoxin, properties. (1/5328)

OBJECTIVE AND SUMMARY BACKGROUND DATA: The recombinant fragment of bactericidal/permeability-increasing protein, rBPI21, has potent bactericidal activity against gram-negative bacteria as well as antiendotoxin (lipopolysaccharide [LPS]) action. On the basis of these activities, the authors sought to discover whether rBPI21 would be protective in baboons with live Escherichia coli-induced sepsis and whether the potential protective effects of rBPI21 (together with antibiotics) would be more closely related to its antibacterial or LPS-neutralizing effects. METHODS: In a prospective, randomized, placebo-controlled subchronic laboratory study, the efficacy of rBPI21 or placebo was studied over 72 hours in chronically instrumented male baboons infused with live E. coli under antibiotic therapy. RESULTS: Intravenous rBPI21 attenuated sepsis-related organ failure and increased survival significantly. Bacteremia was significantly reduced in the rBPI21 group at 2 hours after the start of the E. coli infusion, whereas circulating LPS was less affected. The in vivo formation of tumor necrosis factor was significantly suppressed by the rBPI21 treatment regimen. Microcirculation and organ function were improved. CONCLUSIONS: In baboon live E. coli sepsis, the salutary effect of rBPI21 results from a more prevalent antibacterial than antiendotoxin activity.  (+info)

In vitro activities of cephalosporins and quinolones against Escherichia coli strains isolated from diarrheic dairy calves. (2/5328)

The in vitro activities of several cephalosporins and quinolones against 195 strains of Escherichia coli isolated from diary calves affected by neonatal diarrhea were determined. One hundred thirty-seven of these strains produced one or more potential virulence factors (F5, F41, F17, cytotoxic necrotizing factor, verotoxin, and the eae gene), but the remaining 58 strains did not produce any of these factors. From 11 to 18% of the E. coli strains were resistant to cephalothin, nalidixic acid, enoxacin, and enrofloxacin. However, cefuroxime, cefotaxime, and cefquinome were highly effective against the E. coli isolates tested. Some significant differences (P < 0.05) in resistance to quinolones between the strains producing potential virulence factors and nonfimbriated, nontoxigenic, eae-negative strains were found. Thus, eae-positive, necrotoxigenic, and verotoxigenic (except for nalidixic acid) E. coli strains were significantly more sensitive to nalidixic acid, enoxacin, and enrofloxacin than nonfimbriated, nontoxigenic, eae-negative strains. Moreover, eae-positive strains were significantly more sensitive to enoxacin and enrofloxacin than F5-positive strains. Thus, the result of this study suggest that the bovine E. coli strains that produce some potential virulence factors are more sensitive to quinolones than those that do not express these factors.  (+info)

Augmentation of killing of Escherichia coli O157 by combinations of lactate, ethanol, and low-pH conditions. (3/5328)

The acid tolerance of Escherichia coli O157:H7 strains can be overcome by addition of lactate, ethanol, or a combination of the two agents. Killing can be increased by as much as 4 log units in the first 5 min of incubation at pH 3 even for the most acid-tolerant isolates. Exponential-phase, habituated, and stationary-phase cells are all sensitive to incubation with lactate and ethanol. Killing correlates with disruption of the capacity for pH homeostasis. Habituated and stationary-phase cells can partially offset the effects of the lowering of cytoplasmic pH.  (+info)

Listeria monocytogenes and Escherichia coli septicemia and meningoencephalitis in a 7-day-old llama. (4/5328)

Listeria monocytogenes and Escherichia coli were isolated from blood collected on presentation and tissues samples taken postmortem. Listeria monocytogenes was isolated from cerebrospinal fluid collected antemortem. The importance of passive transfer of immunity, the subtlety of neurologic signs in early meningitis, and considering blood-CSF penetration in antimicrobial selection are discussed.  (+info)

A murine model of renal abscess formation. (5/5328)

We developed a murine model of kidney abscess by direct renal injection of either Escherichia coli (1 x 10(6) to 7 x 10(6) organisms) or sterile medium. Bacterial infection produced renal abscesses, bacteremia, and late-onset leukocytosis in all animals. Controls were unaffected. This model may be useful for the study of various sequelae of kidney infection.  (+info)

Enteropathogenic E. coli attenuates secretagogue-induced net intestinal ion transport but not Cl- secretion. (6/5328)

Enteric bacterial pathogens often increase intestinal Cl- secretion. Enteropathogenic Escherichia coli (EPEC) does not stimulate active ion secretion. In fact, EPEC infection decreases net ion transport in response to classic secretagogues. This has been presumed to reflect diminished Cl- secretion. The aim of this study was to investigate the influence of EPEC infection on specific intestinal epithelial ion transport processes. T84 cell monolayers infected with EPEC were used for these studies. EPEC infection significantly decreased short-circuit current (Isc) in response to carbachol and forskolin, yet 125I efflux studies revealed no difference in Cl- channel activity. There was also no alteration in basolateral K+ channel or Na+-K+-2Cl- cotransport activity. Furthermore, net 36Cl- flux was not decreased by EPEC. No alterations in either K+ or Na+ transport could be demonstrated. Instead, removal of basolateral bicarbonate from uninfected monolayers yielded an Isc response approximating that observed with EPEC infection, whereas bicarbonate removal from EPEC-infected monolayers further diminished Isc. These studies suggest that the reduction in stimulated Isc is not secondary to diminished Cl- secretion. Alternatively, bicarbonate-dependent transport processes appear to be perturbed.  (+info)

Organization of biogenesis genes for aggregative adherence fimbria II defines a virulence gene cluster in enteroaggregative Escherichia coli. (7/5328)

Several virulence-related genes have been described for prototype enteroaggregative Escherichia coli (EAEC) strain 042, which has been shown to cause diarrhea in human volunteers. Among these factors are the enterotoxins Pet and EAST and the fimbrial antigen aggregative adherence fimbria II (AAF/II), all of which are encoded on the 65-MDa virulence plasmid pAA2. Using nucleotide sequence analysis and insertional mutagenesis, we have found that the genes required for the expression of each of these factors, as well as the transcriptional activator of fimbrial expression AggR, map to a distinct cluster on the pAA2 plasmid map. The cluster is 23 kb in length and includes two regions required for expression of the AAF/II fimbria. These fimbrial biogenesis genes feature a unique organization in which the chaperone, subunit, and transcriptional activator lie in one cluster, whereas the second, unlinked cluster comprises a silent chaperone gene, usher, and invasin reminiscent of Dr family fimbrial clusters. This plasmid-borne virulence locus may represent an important set of virulence determinants in EAEC strains.  (+info)

Drosophila melanogaster transferrin. Cloning, deduced protein sequence, expression during the life cycle, gene localization and up-regulation on bacterial infection. (8/5328)

Drosophila melanogaster transferrin cDNA was cloned from an ovarian cDNA library by using a PCR fragment amplified by two primers designed from other dipteran transferrin sequences. The clone (2035 bp) encodes a protein of 641 amino acids containing a signal peptide of 29 amino acids. Like other insect transferrins, Drosophila transferrin appears to have a functional iron-binding site only in the N-terminal lobe. The C-terminal lobe lacks iron-binding residues found in other transferrins, and has large deletions which make it much smaller than functional C-terminal lobes in other transferrins. In-situ hybridization using a digoxigenin labeled transferrin cDNA probe revealed that the gene is located at position 17B1-2 on the X chromosome. Northern blot analysis showed that transferrin mRNA was present in the larval, pupal and adult stages, but was not detectable in the embryo. Iron supplementation of the diet resulted in lower levels of transferrin mRNA. When adult flies were inoculated with bacteria (Escherichia coli), transferrin mRNA synthesis was markedly increased relative to controls.  (+info)

TY - JOUR. T1 - Complete Nucleotide Sequence of an Escherichia coli Sequence Type 410 Strain Carrying blaNDM-5 on an IncF Multidrug Resistance Plasmid and blaOXA-181 on an IncX3 Plasmid. AU - Overballe-Petersen, Søren. AU - Roer, Louise. AU - Ng, Kim Lee. AU - Hansen, Frank. AU - Justesen, Ulrik Stenz. AU - Andersen, Leif P. AU - Stegger, Marc. AU - Hammerum, Anette M. AU - Hasman, Henrik. PY - 2018. Y1 - 2018. N2 - Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored blaNDM-5 and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and blaOXA-181. E. coli isolates with both blaNDM-5 and blaOXA-181 carbapenemases are rare.. AB - Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid ...
ICD-10 A04.1 is enterotoxigenic escherichia coli infection (A041). This code is grouped under diagnosis codes for certain infectious and parasitic diseases.
Clinical and Molecular Epidemiology of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Infections in Metro Detroit: Early Dominance of the ST-131 Clone
Synonyms for Escherichia coli infections in Free Thesaurus. Antonyms for Escherichia coli infections. 1 synonym for Escherichia coli: E. coli. What are synonyms for Escherichia coli infections?
A04.3 is a billable code used to specify a medical diagnosis of enterohemorrhagic escherichia coli infection. Code valid for the fiscal year 2021
Looking for Escherichia coli infections? Find out information about Escherichia coli infections. common bacterium that normally inhabits the intestinal tracts of humans and animals, but can cause infection in other parts of the body, especially the... Explanation of Escherichia coli infections
Extraintestinal pathogenic Escherichia coli (ExPEC) strains of serotype O1:K1:H7/NM are frequently implicated in neonatal meningitis, urinary tract infections and septicemia in humans. They are also commonly isolated from colibacillosis in poultry. Studies to determine the similarities of ExPEC from different origins have indicated that avian strains potentially have zoonotic properties. A total of 59 ExPEC O1:K1:H7/NM isolates (21 from avian colibacillosis, 15 from human meningitis, and 23 from human urinary tract infection and septicemia) originated from four countries were characterized by phylogenetic PCR grouping, Multilocus Sequence Typing (MLST), Pulsed Field Gel Electrophoresis (PFGE) and genotyping based on several genes known for their association with ExPEC or avian pathogenic Escherichia coli (APEC) virulence. APEC and human ExPEC isolates differed significantly in their assignments to phylogenetic groups, being phylogroup B2 more prevalent among APEC than among human ExPEC (95% vs. 53%, P =
TY - JOUR. T1 - Dose-dependent differential resistance of inbred chicken lines to avian pathogenic Escherichia coli challenge. AU - Alber, Andreas. AU - Costa, Taiana. AU - Chintoan-Uta, Cosmin. AU - Bryson, Karen J. AU - Kaiser, Pete. AU - Stevens, Mark P. AU - Vervelde, Lonneke. PY - 2018/12/20. Y1 - 2018/12/20. N2 - Avian pathogenic E. coli (APEC) cause severe respiratory and systemic disease. To address the genetic and immunological basis of resistance, inbred chicken lines were used to establish a model of differential resistance to APEC, using strain O1 of serotype O1:K1:H7. Inbred lines 72, 15I and C.B12 and the outbred line Novogen Brown were inoculated via the airsac with a high dose (107 colony-forming units, CFU) or low dose (105 CFU) of APEC O1. Clinical signs, colibacillosis lesion score and bacterial colonisation of tissues after high dose challenge were significantly higher in line 15I and C.B12 birds. The majority of the 15I and C.B12 birds succumbed to the infection by 14 hours ...
INTRODUCTION Animals are considered to be reservoirs of extended-spectrum beta-lactamase (ESBL)-producing bacteria, but few epidemiological data on ESBL-producing Escherichia coli urinary tract isolates in pet dogs are available in China. METHODOLOGY This study was conducted to describe the prevalence and characterization of ESBL producers among E. coli urinary tract isolates from pet dogs in Taian, China. RESULTS A total of 118 E. coli were obtained from urinary samples of 80 companion dogs suffering from acute or chronic cystitis, of which three isolates from different dogs were ESBL producers. One isolate from dog A was of phylogroup A/ST410/CTX-M-15/TEM-1; one from dog B was of phylogroup B1/ST533/CTX-M-15/TEM-1; one from dog C was of phylogroup D/ST648/CTX-M-15. All ESBL producers were resistant to ampicillin, cephalexin, cefalotin, cefpodoxime, ceftiofur, enrofloxacin, marbofloxacin, and trimethoprim/sulfamethoxazole, but were susceptible to imipenem and amoxicillin/clavulanic acid. E. coli
Looking for Enteroaggregative Escherichia Coli? Find out information about Enteroaggregative Escherichia Coli. common bacterium that normally inhabits the intestinal tracts of humans and animals, but can cause infection in other parts of the body, especially the... Explanation of Enteroaggregative Escherichia Coli
TY - JOUR. T1 - Role of virulence factors on host inflammatory response induced by diarrheagenic Escherichia coli pathotypes. AU - Sanchez-Villamil, Javier. AU - Navarro-Garcia, Fernando. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Pathogens are able to breach the intestinal barrier, and different bacterial species can display different abilities to colonize hosts and induce inflammation. Inflammatory response studies induced by enteropathogens as Escherichia coli are interesting since it has acquired diverse genetic mobile elements, leading to different E. Coli pathotypes. Diarrheagenic E. Coli secrete toxins, effectors and virulence factors that exploit the host cell functions to facilitate the bacterial colonization. Many bacterial proteins are delivered to the host cell for subverting the inflammatory response. Hereby, we have highlighted the specific processes used by E. Coli pathotypes, by that subvert the inflammatory pathways. These mechanisms include an arrangement of pro- and anti-inflammatory ...
We examined extended-spectrum β-lactamase-producing isolates from livestock, humans, companion animals, food, and the environment during 2009-2016 in Germany for the presence of CTX-M-27 allele within Escherichia coli sequence type (ST) 131. E. coli ST131 C1-M27 was exclusively present in humans; its incidence increased from 0% in 2009 to 45% in 2016.
Escherichia coli bacteria cause many illnesses of the gastrointestinal tract. Often, people come down with these diseases when they eat contaminated foods, especially ground beef or raw produce. Though E. coli infections are most common in less developed parts of the world, they are also a problem in the United States-contamination occurred in prepackaged cookie dough in 2009 and in spinach in 2006. But all E. coli are not harmful, as strains found in the human intestinal system can help with vitamin K production or in fighting harmful bacteria. This revised edition of Escherichia coli Infections contains up-to-date information on the different strains of E. coli, including the latest outbreaks, statistics, diagnostic breakthroughs, and vaccine development ...
Escherichia coli (E. coli) is one of the important causative pathogens of neonatal invasive infection. The epidemiological and clinical profile of invasive E. coli infection in Chinese newborns is not well characterized. Ninety-four infants with invasive E. coli infection were categorized into E. coli early onset disease (EOD) group (onset ≤72 h after birth) (n = 46) and E. coli late onset disease (LOD) group (onset | 72 h) (n = 48). We compared and analyzed the clinical characteristics and drug sensitivity profile of early-onset and late-onset E. coli invasive infection in neonates. The incidence of E. coli-EOD and E.coli-LOD was 0.45/1000 live births (LBs) and 0.47/1000 LBs, respectively. The incidence of gestational diabetes mellitus, perinatal fever, urinary tract infection, chorioamnionitis, and positive E. coli culture among mothers in the E. coli-EOD group were significantly higher than that in E. coli-LOD group. The incidence of premature birth, low-birth-weight, nosocomial infection, and
Escherichia Coli Infection (E Coli Infection): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis.
A single E. coli clonal group, ST131, probably caused the most significantly antimicrobial-resistant E. coli infections in the United States in 2007, thereby constituting an important new public health threat. Enhanced virulence and/or antimicrobial resistance compared with other E. coli, plus ongoi …
TY - JOUR. T1 - Diarrheagenic Escherichia coli and Virulence Determinants. AU - Okamoto, Keinosuke. AU - Yamanaka, Hiroyasu. AU - Fujii, Yoshio. PY - 1991/1/1. Y1 - 1991/1/1. N2 - Escherichia coli is normally the most common facultative anaerobe in the large bowel and usually nonpathogenic for man. However, some E. coli strains which cause distinct syndromes of diarrhea diseases have been proved to be pathogenic. These organisms are one of the most common causes of food poisoning in Japan. In developing countries, these pathogens are known to be main causative agents of diarrhea which is the major cause of infantile morbidity and mortality. These E. coli strains are divided into four groups: enteropathogenic E. coli (EPEC), enter-oinvasive E. coli (EIEC), enterotoxigenic E. coli (ETEC), and enterohemorrhagic E. coli (EHEC). The four groups are distinguished on the basis of pathogenic, clinical, and epidemiologic features. Moreover, the fifth group of diarrheagenic E. coli, termed ...
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Presence and characterization of extraintestinal pathogenic Escherichia coli (ExPEC) virulence genes in F165-positive E. coli strains from diseased calves and pigs
When both glucose and lactose are present in the growth medium, the uptake of lactose is strongly inhibited by glucose because of an increase in the nonphosphorylated form of IIAGlc, an inhibitor of lac permease. Mechanism responsible for glucose-lactose diauxie in Escherichia coli - challenge to the cAMP model
Eight newborn calves were challenged orally with a known enteropathogenic strain of Escherichia coli 0101 K?(A) and two to six hours later each calf was fed a minimum of three pints colostrum. All calves suffered from acute diarrhoea of varying severity within 24 to 48 hours of infection. Immunofluorescent and histological examination of the small intestine demonstrated adherence of the challenge organism to the epithelium and the presence of pathological lesions similar to those seen in colostrum-deprived calves with enteric colibacillosis. It was concluded that in order to be effective prophylactically, colostrum must be fed prior to infection.. ...
Although Escherichia coli infections are common throughout the developing world, their prevalence patterns in space and over time are not well characterized. We used serial case control data collected from 16 communities in northwestern Ecuador between 2004 and 2010, to examine the prevalence of enteroinvasive E. coli (EIEC) and enterotoxigenic E. coli (ETEC). At its peak, the regional prevalence of EIEC was 8.3 infections/100 persons but this decreased to 1 infection/1,000 persons. The regional prevalence of ETEC ranged from 8 infections/1,000 persons to 3.7 infections/100 persons. The prevalence pattern of EIEC resembled that of a large epidemic whereas the prevalence Although Escherichia coli infections are common throughout the developing world, their prevalence patterns in space and over time are not well characterized. We used serial case control data collected from 16 communities in northwestern Ecuador between 2004 and 2010, to examine the prevalence of enteroinvasive E. coli (EIEC) and ...
Synonyms and Keywords: Colibacillosis, E. coli enteritis, E. coli gastroenteritis, E. coli colitis, E. coli dysentery, E. coli diarrhea, Diarrheagenic E. coli infection, ETEC (toxigenic E. coli) infection, EHEC (enterohemorrhagic E. coli) infection, STEC (Shiga-like toxin producing E. coli), VTEC (Veratoxin-producing E. coli), EPEC (enteropathogenic E. coli) infection, EAEC (enteroaggregative E. coli) infection, EIEC (enteroinvasive E. coli) infection, DAEC (diffusely adherent E. coli) infection ...
Risk Assessment of Escherichia coli Infection from Use of Interactive Waterscape Facilities - Escherichia coli;Exposure;Interactive fountain;Risk assessment;
BACKGROUND: Escherichia coli producing ESBL/AmpC enzymes are unwanted in animal production chains as they may pose a risk to human and animal health. Molecular characterization of plasmids and strains carrying genes that encode these enzymes is essential to understand their local and global spread. OBJECTIVES: To investigate the diversity of ... read more genes, plasmids and strains in ESBL/AmpC-producing E. coli from the Colombian poultry chain isolated within the Colombian Integrated Program for Antimicrobial Resistance Surveillance (Coipars). METHODS: A total of 541 non-clinical E. coli strains from epidemiologically independent samples and randomly isolated between 2008 and 2013 within the Coipars program were tested for antimicrobial susceptibility. Poultry isolates resistant to cefotaxime (MIC ≥ 4 mg/L) were screened for ESBL/AmpC genes including blaCTX-M, blaSHV, blaTEM, blaCMY and blaOXA. Plasmid and strain characterization was performed for a selection of the ESBL/AmpC-producing ...
The intimin gene eae, located within the locus of enterocyte effacement pathogenicity island, distinguishes enteropathogenic Escherichia coli (EPEC) and some Shiga toxin-producing E. coli (STEC) strains from all other pathotypes of diarrheagenic E. coli. EPEC is a leading cause of infantile diarrhea in developing countries, and intimin-positive STEC isolates are typically associated with life-threatening diseases such as hemolytic-uremic syndrome and hemorrhagic colitis. Here we describe the development of a PCR-restriction fragment length polymorphism (RFLP) assay that reliably differentiates all 11 known intimin types (α1, α2, β, γ, κ, ɛ, η, ι, λ, θ, and ζ) and three new intimin genes that show less than 95% nucleotide sequence identity with existing intimin types. We designated these new intimin genes Int-μ, Int-ν, and Int-ξ. The PCR-RFLP assay was used to screen 213 eae-positive E. coli isolates derived from ovine, bovine, and human sources comprising 60 serotypes. Of these, 82 were
Click to launch & play an online audio visual presentation by Prof. Michael Donnenberg on The diversity of Escherichia coli infections, part of a collection of online lectures.
Learn more about Escherichia coli Infection at Medical City Dallas DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
The Report Escherichia coli Infections Global Clinical Trials Review, H2, 2016 provides information on pricing, market analysis, shares, forecast, and...
Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli (EHEC) are closely related pathogenic strains of Escherichia coli. The hallmark of EPEC/EHEC infections [DS:H00278 H00277] is induction of attaching and effacing (A/E) lesions that damage intestinal epithelial cells. The capacity to form A/E lesions is encoded mainly by the locus of enterocyte effacement (LEE) pathogenicity island. Tir, Map, EspF, EspG are known LEE-encoded effector proteins secreted via the type III secretion system, which is also LEE-encoded, into the host cell. EPEC and EHEC Tirs link the extracellular bacterium to the cell cytoskeleton. Map and EspF are involved in mitochondrion membrane permeabilization. EspG interacts with tubulins and stimulates microtubule destabilization. LEE-encoded adhesin or intimin (Eae) is exported via the general secretory pathway to the periplasm, where it is inserted into the outer membrane. In addition to Tir, two potential host cell-carried intimin receptors, beta1 integrin (ITGB1) ...
Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli (EHEC) are closely related pathogenic strains of Escherichia coli. The hallmark of EPEC/EHEC infections [DS:H00278 H00277] is induction of attaching and effacing (A/E) lesions that damage intestinal epithelial cells. The capacity to form A/E lesions is encoded mainly by the locus of enterocyte effacement (LEE) pathogenicity island. Tir, Map, EspF, EspG are known LEE-encoded effector proteins secreted via the type III secretion system, which is also LEE-encoded, into the host cell. EPEC and EHEC Tirs link the extracellular bacterium to the cell cytoskeleton. Map and EspF are involved in mitochondrion membrane permeabilization. EspG interacts with tubulins and stimulates microtubule destabilization. LEE-encoded adhesin or intimin (Eae) is exported via the general secretory pathway to the periplasm, where it is inserted into the outer membrane. In addition to Tir, two potential host cell-carried intimin receptors, beta1 integrin (ITGB1) ...
Enteroaggregative Escherichia coli is a major cause of diarrhea in diverse populations worldwide. EAEC has a characteristic stacked-brick adherence pattern to intestinal epithelial cells which is mediated the aggregative adherence fimbria (AAF). The AraC-like regulator AggR has been found to regulate expression of the genes encoding the AAF and several other virulence associated genes. Multiple epidemiologic studies have found an association between possession of aggR and EAEC disease. However, the exact factor(s) responsible for diarrheal disease remain unclear. A microarray approach was used to identify AggR-regulated genes in EAEC strain 042. Nineteen previously unrecognized genes were found to be regulated by AggR. Three of these genes were chosen for further study based on a high prevalence in an EAEC strain collection. Two of the genes (orf3 and orf4) were found to cause an increase in resistance to cationic antimicrobial peptides. The third (orf61) is a novel membrane damaging toxin ...
|jats:title|ABSTRACT|/jats:title||jats:p|OXA-48-like enzymes have emerged as important extended-spectrum β-lactamases/carbapenemases in|jats:named-content xmlns:xlink= content-type=genus-species xlink:type=simple|Escherichia coli|/jats:named-content|sequence type 131 (ST131). We report the structures of the first fully sequenced|jats:italic|bla|/jats:italic||jats:sub|OXA-163|/jats:sub|plasmid and of two other|jats:italic|bla|/jats:italic||jats:sub|OXA-48|/jats:sub|plasmids in this lineage.|jats:italic|bla|/jats:italic||jats:sub|OXA-163|/jats:sub|was located on a 71-kb IncN plasmid with other resistance genes.|jats:italic|bla|/jats:italic||jats:sub|OXA-48|/jats:sub|was present on IncL/M plasmids, genetically similar to other|jats:italic|bla|/jats:italic||jats:sub|OXA-48|/jats:sub|plasmid sequences, and consistent with interspecies/interlineage spread. The presence of|jats:italic|bla|/jats:italic||jats:sub|OXA-48-like|/jats:sub|genes on epidemic plasmids in ST131 is of
Urinary tract infection (UTI) is the most common form of extraintestinal Escherichia Coli infection (E.coli), and E. coli is the most common cause of UTI.The aim of this paper is to study the uropathogenicity factors for some strains of E.coli involved in the etiology of UTI and the affiliationof urinary E.coli strains to the serogroups involved in the UTI.We studied 208 strains of E. coli from urine samples sterilely collected from patients with clinical suspicion of urinary tract infection.The study was conducted in Emergency County Hospital Craiova between 2012-2014.Out of the 208 strains of E. coli submitted to the study, 60 strains (28.84%) - MRHA with human red cells, 28 strains (13.50%) - MRHA human red cells and blood red cells MSHA with guinea pigs, and 44 strains (21.12%) - MSHA with guinea pig red blood cells; 76 strains (36.54%) - no hemagglutination. Regarding our study, 42,34% of E.coli strains presented human MRHA putting forward their potential to cause pyelonephritits. The 68
TY - JOUR. T1 - Clinical significance and phylogenetic background of extended spectrum β-lactamase producing Escherichia coli isolates from extra-intestinal infections. AU - Chakraborty, Arindam. AU - Adhikari, Prabha. AU - Shenoy, Shalini. AU - Saralaya, Vishwas. PY - 2015/5/1. Y1 - 2015/5/1. N2 - Introduction: Escherichia coli producing extended spectrum-β-lactamases (ESBL), particularly CTX-M type ESBLs, have rapidly spread worldwide and pose a serious threat for healthcare-associated infections. We performed a molecular detection and characterization study of ESBL-related bla genes, including blaTEM, blaSHV, blaCTX-M, and blaCTX-M15, and also assessed the relationship between the phylogenetic background of strains carrying ESBL genes and the patients clinical outcome. Methodology: A total of 300 non-repeated, clinically significant isolates were investigated. The molecular types of ESBL genes were determined using multiplex PCR. Phylogenetic analysis was performed using triplex PCR ...
Escherichia coli colonizes the human intestine shortly after birth, with most strains engaging in a commensal relationship. However, some E. coli strains have evolved toward acquiring genetic traits associated with virulence. Currently, five categories of enteroadherent E. coli strains are well-recognized, and are classified in regard to expressed adhesins and the strategy used during the colonization. The high morbidity associated with diarrhea has motivated investigations focusing on E. coli adhesins, as well on factors that inhibit bacterial adherence. Breastfeeding has proved to be the most effective strategy for preventing diarrhea in children. Aside from the immunoglobulin content, glycocompounds and oligosaccharides in breast milk play a critical role in the innate immunity against diarrheagenic E. coli strains. This review summarizes the colonization factors and virulence strategies exploited by diarrheagenic E. coli strains, addressing the inhibitory effects that oligosaccharides and
Abe CM, Salvador FA, Falsetti IN, Vieira MA, et al. (2008). Uropathogenic Escherichia coli (UPEC) strains may carry virulence properties of diarrhoeagenic E. coli. FEMS Immunol. Med. Microbiol. 52: 397-406. PMid:18336383 Antão EM, Wieler LH and Ewers C (2009). Adhesive threads of extraintestinal pathogenic Escherichia coli. Gut. Pathog. 1: 22. Aranda KR, Fagundes-Neto U and Scaletsky IC (2004). Evaluation of multiplex PCRs for diagnosis of infection with diarrheagenic Escherichia coli and Shigella spp. J. Clin. Microbiol. 42: 5849-5853. PMid:15583323 PMCid:535216 Arslan H, Azap OK, Ergönül Ö and Timurkaynak F (2005). Risk factors for ciprofloxacin resistance among Escherichia coli strains isolated from community-adquired urinary tract infections in Turkey. J. Antimicrob. Chemother. 56: 914-918. PMid:16174685 Binns MM, Mayden J and Levine RP (1982). ...
The term enteropathogenic Escherichia coli was originally used to refer to strains belonging to a limited number of O groups epidemiologically associated with infantile diarrhea ( 1 ). Subsequently, E. coli strains isolated from intestinal diseases have been grouped into at least six main categories on the basis of epidemiological evidence, phenotypic traits, clinical features of the disease they produce, and specific virulence factors. The well-described intestinal pathotypes or categories of diarrheagenic E. coli groups are enteropathogenic E. coli (EPEC), Shiga toxin-producing E. coli (STEC) or verocytotoxin-producing E. coli (VTEC) (including enterohemorrhagic E. coli [EHEC]), enterotoxigenic E. coli (ETEC), enteroaggregative E. coli (EAEC), enteroinvasive E. coli, and diffusely adherent E. coli. The general definition of an E. coli pathotype as a group of strains of a single species that cause a common disease using a common set of virulence factors ( 2 ) has been further refined for STEC ...
Pathogenic Escherichia coli strains carrying the afa-8 gene cluster are frequently associated with extra-intestinal infections in humans and animals. The
E. coli possesses four iron uptake systems that use siderophores such as enterobactin and aerobactin, produced by E. coli, or the fungal siderophores ferrichrome and coprogen. Iron acquisition by this bacterium can also occur in a process mediated by citrate ((1), (5)). Pathogenic E. coli strains are able to use heme compounds as iron sources, but so far little is known about the mechanisms involved in this kind of iron uptake ((10)). The results of this study suggest that the human pathogenic E. coli strain EB1 contains a hemophore-dependent heme acquisition system. The bacterium secretes a heme-binding protein (Hbp) with an estimated size of 110 kD, that degrades hemoglobin. It is likely that Hbp is the shuttle protein of this heme-scavenging system in E. coli.. Recently, an exported protease (PssA) from a Shiga toxin-producing E. coli has been characterized ((43)). Sequence comparison showed that PssA is related to the family of autotransporter proteins, especially to SepA of S. flexneri ...
E. coli is a type of gram negative bacteria that lives in the gastrointestinal tract of people and animals. Some E. coli bacteria strains in contaminated food and water can cause diarrhea, urinary tract infections and abdominal cramps.
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34. 35. . Bursitis sternalis (inflammation of the sternal bursa). The bursa is enlarged in a various extent and filled with inflammatory exudate. The diagnosis of coli - infections is based on isolation and typization of pathogenic E. coli serotypes. Many other bacteria (salmonellae, pasteurellae, staphylococci etc.), viruses, chlamydiae and mycoplasmae should be excluded as possible aetiological agents. The prevention should aim at minimizing the probability of faecal contamination of eggs. This implies the maintenance of clean nests, discarding floor eggs and removal of eggs that are cracked or contaminated with faeces. Breeder eggs should be fumigated or disinfected in the farm prior to their transportation in the storage premise. The treatment is effective if initiated soon after testing the antibacterial sensitivity of isolates.. ...
34. 35. . Bursitis sternalis (inflammation of the sternal bursa). The bursa is enlarged in a various extent and filled with inflammatory exudate. The diagnosis of coli - infections is based on isolation and typization of pathogenic E. coli serotypes. Many other bacteria (salmonellae, pasteurellae, staphylococci etc.), viruses, chlamydiae and mycoplasmae should be excluded as possible aetiological agents. The prevention should aim at minimizing the probability of faecal contamination of eggs. This implies the maintenance of clean nests, discarding floor eggs and removal of eggs that are cracked or contaminated with faeces. Breeder eggs should be fumigated or disinfected in the farm prior to their transportation in the storage premise. The treatment is effective if initiated soon after testing the antibacterial sensitivity of isolates ...
A human challenge model was developed to study nutritional interventions to prevent infection with diarrhoeagenic Escherichia coli, one of the major and most common causes of diarrhea. Challenges with high doses of E. coli was shown to prevent clinical symptoms upon re-infection. Here we aimed to study if a low dose primary E. coli challenge induced only partial protection against re-infection. Thirty healthy male volunteers were selected,randomized, and orally exposed to increasing concentrations of E. coli strain E1392/75-2A(10e6, 10e7, 10e8, 10e9, and 10e10 CFU). Clinical symptoms of gastrointestinal discomfort were recorded, and stool and blood samples were collected. These were analyzed for immunological responses, stool characteristics, and inflammatory markers. After primary infection,E. coli-specific serum IgG(CFA/II) titers increased in a dose-dependent manner.Three weeks later, all volunteers were re-infected with a high E. coli dose(10e10 CFU). Surprisingly,all primary E. coli doses ...
In this study, we assessed the phylogroup distribution, virulence genotype, ExPEC status, and, selectively, PFGE profile and ST of 595 E. coli isolates obtained from diverse surface water sites and the feces of various wild and domesticated animals. All isolates were collected in Minnesota and Wisconsin in 1999 to 2002. Our four main findings were as follows: (i) an overall predominance of phylogroups A and B1, but with considerable variation by site and species; (ii) an overall scarcity of virulence genes and ExPEC isolates, but with considerable variation by animal species; (iii) strong associations of ExPEC status with phylogroups B2 (positive) and B1 (negative); and (iv) close PFGE correspondence between certain study isolates and archival human clinical and fecal isolates, involving familiar virulence-associated STs. These mostly reassuring findings suggest that E. coli strains that presumably can cause human extraintestinal infections are not prominent overall within the E. coli population ...
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Extraintestinal pathogenic Escherichia coli (ExPEC) strains are responsible for a majority of human extraintestinal infections globally, resulting in enormous direct medical and social costs. ExPEC strains are comprised of many lineages, but only a subset is responsible for the vast majority of infections. Few systematic surveillance systems exist for ExPEC.. ...
Uropathogenic E. coli are paradoxically able to both cause disease in the urinary tract, and reside there asymptomatically. The pandemic, multi-drug resistant E. coli subclone ST131-H30 (H30) is of special interest, as it has been found to persist in the gut and bladder of healthy people. In order to understand this persistence, we investigated whether H30 is competitive in these niches and thus able to persist by excluding other E. coli, as well as whether H30 may persist via within-host adaptation. In order to assess the E. coli clonal landscape, we developed a novel method based on deep sequencing of two loci, along with an algorithm for analysis of resulting data. Using this method, we assessed fecal and urinary samples from healthy women carrying H30, and found that even in the absence of antibiotic use, H30 could completely dominate the gut and, especially, urine of healthy carriers. In order to ascertain whether H30 adapts within host, we employed population-level whole genome sequencing, ...
... coli and several other organisms E. coli statistics E. coli Infection , Causes & Risk Factors Bacteriome E. coli interaction ... "Escherichia coli Infections - Infections". MSD Manual Consumer Version. Retrieved 6 October 2021. Darnton NC, Turner L, ... Wikispecies has information related to Escherichia coli. Wikimedia Commons has media related to Escherichia coli. EcoCyc - ... coli infections outside the digestive tract and most intestinal infections but are not used to treat intestinal infections by ...
Manning, Shannon D. (April 1, 2010). Escherichia coli Infections (2nd ed.). New York, NY: Chelsea House Publishers. ISBN ... Davis, M. (April 16, 1993). "Update: Multistate Outbreak of Escherichia coli O157:H7 Infections from Hamburgers - Western ... The 1992-1993 Jack in the Box E. coli outbreak occurred when the Escherichia coli O157:H7 bacterium (originating from ... coli O157:H7 infection later tied to the same outbreak. Two-year-old Michael Nole of Tacoma, WA, who died on January 22, 1993, ...
"Escherichia coli O157 infection associated with a petting zoo". Epidemiology and Infection. 129 (2): 295-302. doi:10.1017/ ... coli. List of strains of Escherichia coli "Escherichia coli O157:H7". CDC Division of Bacterial and Mycotic Diseases. Retrieved ... "Escherichia coli in chronic inflammatory bowel diseases: An update on adherent invasive Escherichia coli pathogenicity". World ... 29 June 2000). "The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections". N ...
PDI) Thorpe, C. M. (1 May 2004). "Shiga Toxin--Producing Escherichia coli Infection". Clinical Infectious Diseases. 38 (9): ... "Two distinct cytotoxic activities of subtilase cytotoxin produced by shiga-toxigenic Escherichia coli". Infection and Immunity ... Norton, E. B.; Lawson, L. B.; Mahdi, Z.; Freytag, L. C.; Clements, J. D. (23 April 2012). "The A Subunit of Escherichia coli ... Shiga toxin, also known as Stx, is a toxin that is produced by the rod shaped Shigella dysenteriae and Escherichia coli (STEC ...
... intestinal parasite infections like Giardia; and bacterial infections such as Escherichia coli. Anal sex should be avoided by ... January 2001). "Diagnosis of primary HIV-1 infection. Los Angeles County Primary HIV Infection Recruitment Network". Annals of ... infection: national case surveillance data during 20 years of the HIV epidemic in the United States". Infection Control and ... Putting a condom on a sex toy provides better sexual hygiene and can help to prevent transmission of infections if the sex toy ...
Edén CS, Hagberg L, Hanson LA, Korhonen T, Leffler H, Olling S (2008). "Adhesion of Escherichia coli in urinary tract infection ...
Enteroaggregative Escheichia coli (EAEC) is a type of strain from E.coli. E.coli causes intestinal infections, some intestinal ... coli (EPEC), enterotoxigenic E.coli (ETEC), Shiga toxin-producing E. coli (STEC) and Enteroaggregative E. coli (EAEC). E. coli ... Enteroaggregative Escherichia coli (EAEC or EAggEC) are a pathotype of Escherichia coli which cause acute and chronic diarrhea ... Nataro, James P.; Steiner, Theodore (2002), "Enteroaggregative and Diffusely Adherent Escherichia Coli", Escherichia Coli, ...
"Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection". The Journal of Clinical Investigation. 92 ( ... Intimin is a virulence factor (adhesin) of EPEC (e.g. E. coli O127:H6) and EHEC (e.g. E. coli O157:H7) E. coli strains. It is ... "A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K- ... Jerse AE, Yu J, Tall BD, Kaper JB (October 1990). "A genetic locus of enteropathogenic Escherichia coli necessary for the ...
Justice, Sheryl S.; Hunstad (2006). "Filamentation by Escherichia coli subverts innate defenses during urinary tract infection ... As an example of this, during urinary tract infection, filamentatious structures of uropathogenic E. coli (UPEC) start to ... This mechanism has been described in bacteria such as Escherichia coli and Helicobacter pylori. Oxidative stress, nutrient ... "The role of DNA base excision repair in filamentation in Escherichia coli K-12 adhered to epithelial HEp-2 cells". Antonie van ...
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Arabic) Robert Holdstock, 61, British science fiction author, Escherichia coli infection. Solange Magnano, 38, Argentinian ... Alice McGrath, 92, American activist (Sleepy Lagoon murder trial), infection from a chronic illness. Sir Anthony Mullens, 73, ... complications from staphylococcal infection. Robert H. Rines, 87, American scientist, inventor, composer and Loch Ness Monster ...
The most common cause of urinary tract infections is Escherichia coli. Testing for bacteriuria is usually performed in people ... Escherichia coli is the most common bacterium found. People without symptoms should generally not be tested for the condition. ... bacteriuria without accompanying symptoms of a urinary tract infection and is commonly caused by the bacterium Escherichia coli ... Nicolle LE (March 2014). "Urinary tract infections in special populations: diabetes, renal transplant, HIV infection, and ...
2015). "Examination of the Enterotoxigenic Escherichia coli Population Structure during Human Infection". mBio. 6 (3): e00501. ... "Temporal Variability of Escherichia coli Diversity in the Gastrointestinal Tracts of Tanzanian Children with and without ... "Compositional and Functional Differences in the Human Gut Microbiome Correlate with Clinical Outcome following Infection with ... complete genome of a free-living organism-Haemophilus influenzae-the bacterium that causes lower respiratory tract infections ...
It is typically due to a bacterial infection, most commonly Escherichia coli. Risk factors include sexual intercourse, prior ... Common organisms are E. coli (70-80%) and Enterococcus faecalis. Hospital-acquired infections may be due to coliform bacteria ... The mechanism of infection is usually spread up the urinary tract. Less often infection occurs through the bloodstream. ... Most cases of pyelonephritis start off as lower urinary tract infections, mainly cystitis and prostatitis. E. coli can invade ...
"Phosphorus incorporation in Escherichia coli ribonucleic acid after infection with bacteriophage T2". Virology. 2 (2): 149-161 ... "Unstable ribonucleic acid revealed by pulse labelling of Escherichia coli". Nature. 190 (4776): 581-5. Bibcode:1961Natur.190.. ... In 1953, Alfred Day Hershey reported that soon after infection with phage, bacteria produced a form of RNA at a high level and ... They found out that the protein synthesis of E.coli was stopped and phage proteins were synthesized. Then, in May 1961, their ...
McClain, William H.; Guthrie, Christine; Barrell, B. G. (1972). "Eight Transfer RNAs Induced by Infection of Escherichia coli ...
2011). "Urinary tract infections of Escherichia coli strains of chaperone-usher system". Polish Journal of Microbiology. 60 (4 ... localisation and biofilm formation in clinically important species such as uropathogenic Escherichia coli and Pseudomonas ...
Niranjan V, Malini A (June 2014). "Antimicrobial resistance pattern in Escherichia coli causing urinary tract infection among ... March 2014). "Type 1 fimbriae contribute to catheter-associated urinary tract infections caused by Escherichia coli". Journal ... Escherichia coli biofilms are responsible for many intestinal infectious diseases. The Extraintestinal group of E. coli (ExPEC ... urinary tract infections, catheter infections, middle-ear infections, formation of dental plaque, gingivitis, coating contact ...
April 1997). "Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination". Science. 276 (5312 ... "Vaccination with FimH adhesin protects cynomolgus monkeys from colonization and infection by uropathogenic Escherichia coli". J ... the adhesin of uropathogenic Escherichia coli (UPEC). Work with E. coli stems from observations of human acquired immunity. ... Escherichia coli strains most known for causing diarrhea can be found in the intestinal tissue of pigs and humans where they ...
1 August 1996). "A new route of transmission for Escherichia coli: infection from dry fermented salami". American Journal of ... She was a lead investigator at FSIS for the 1992-1993 Jack in the Box E. coli outbreak. She was a co-author of the Pathogen ...
"An outbreak of Escherichia coli O157:H7 infection from unpasteurized commercial apple juice". Ann Intern Med. 130 (3): 202-9. ... Escherichia coli outbreaks, Health in California, Health in Colorado, Disease outbreaks in the United States, Apple drinks). ... p. 5. "Questions of Pasteurization Raised After E. coli Is Traced to Juice". The New York Times. New York. November 4, 1996. ... Burros, Marian (November 20, 1996). "Opting for an Early Warning When E. coli Is Suspected". The New York Times. New York. ...
"An outbreak of Escherichia coli O157:H7 infection from unpasteurized commercial apple juice". Annals of Internal Medicine. 130 ... During her fellowship as an EIS officer, she investigated the 1996 international outbreak of E. coli O157:H7 that was linked to ...
"Complicated Catheter-Associated Urinary Tract Infections Due to Escherichia coli and Proteus mirabilis". Clinical Microbiology ... Sepsis (infection of the blood) may occur as a complication of a bacterial, viral, or fungal infection. Miscarriage is the most ... Infection of the middle ear. Meningitis. Infection of the meninges of the central nervous system (brain and spinal cord) that ... Common microbes involved in HAIs are Escherichia coli, Proteus mirabilis, and Clostridium difficile. The most effective ...
This could lead to infections such as Escherichia coli, Trichinellosis or Streptococcus suis. According to the rating institute ...
"Visualization of bacteriophage P1 infection by cryo-electron tomography of tiny Escherichia coli". Virology. 417 (2): 304-311. ... The first minicells reported were from a strain of Escherichia coli that had a mutation in the Min System that lead to mis- ... Adler, H. I.; Fisher, W. D.; Cohen, A.; Hardigree, A. A. (1967-02-01). "MINIATURE escherichia coli CELLS DEFICIENT IN DNA". ... including Escherichia coli and Salmonella enterica, have been reported, but in principle, minicells could be generated for any ...
"Bacterial virulence characteristics of Escherichia coli isolates from first-time urinary tract infection". J. Infect. Dis. 171 ... Urinary tract infections (UTIs) are often due to E. coli entering the urethra and colonizing. The host's immune system will ... OmpT is an aspartyl protease found on the outer membrane of Escherichia coli. OmpT is a subtype of the family of omptin ... Zanfardino A, Pizzo E, Di Maro A, Varcamonti M, D'Alessio G (April 2010). "The bactericidal action on Escherichia coli of ZF- ...
Mellata, Melha (November 2013). "Human and Avian Extraintestinal Pathogenic Escherichia coli: Infections, Zoonotic Risks, and ... Because the infection can spread via the lymph vessels, infection in one Fallopian tube usually leads to infection of the other ... Other complications are: Infection of ovaries and uterus Infection of sex partners An abscess on the ovary Internal scars ... E. coli, Gallibacterium and other bacteria can cause salpingitis in chickens and other poultry. This can result in lower egg ...
Currie, A. (2018). "Outbreak of Escherichia coli 0157:H7 Infections Linked to Aged Raw Milk Gouda Cheese". Journal of Food ... Additionally, depending on the severity of infection, there may be further threat to human health. Infection has the potential ... coli, Salmonella, and streptococcal infections, make it potentially unsafe to consume. Similarly, a recent review authored by ... A review study published in the Journal of Food Protection showed that E. coli 0157:H7 has the ability to persist through the ...
1996). "A new route of transmission for escherichia coli: Infection from dry fermented salami". American Journal of Public ... In 1994, there was an outbreak of Escherichia coli O157 with 17 cases all occurring from the consumption of pre-sliced salami ...
"Escherichia coli mediated urinary tract infections: are there distinct uropathogenic E. coli (UPEC) pathotypes?" (PDF). FEMS ... E. coli carrying genes for PapGI and PapGIV are rarely found in E. coli causing infections in humans. Nuccio SP, et al. (2007 ... E. coli strains carrying the papGIII gene are associated with lower urinary tract infections (cystitis) and asymptomatic ... Johanson IM, Plos K, Marklund BI, Svanborg C (August 1993). "Pap, papG and prsG DNA sequences in Escherichia coli from the ...
... a CRISPR Cas3-enhanced bacteriophage against Escherichia coli bacteria which cause urinary tract infections. Twenty patients ... The intended therapeutic targets are antibiotic-resistant bacterial infections. The company was founded as a spin-off from ...
In May 2010, a case of infection with E. coli expressing NDM-1 was reported in Coventry in the United Kingdom. The patient was ... The most common bacteria that make this enzyme are gram-negative such as Escherichia coli and Klebsiella pneumoniae, but the ... The infection was identified as a carbapenem-resistant Klebsiella pneumoniae strain bearing the novel gene blaNDM-1. The ... in December 2009 in a Swedish national who fell ill with an antibiotic-resistant bacterial infection that he acquired in India ...
Light S, Kraulis P (February 2004). "Network analysis of metabolic enzyme evolution in Escherichia coli". BMC Bioinformatics. 5 ... have been validated as important during various stages of the infection lifecycle of M. tuberculosis. Amino acids are either ... being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants ...
"Update on Multi-State Outbreak of E. coli O157:H7 Infections From Fresh Spinach". Centers for Disease Control and Prevention. ... Escherichia coli outbreaks, Food and drink in Canada, Food recalls, Health disasters in Canada, Disease outbreaks in the United ... coli infections after eating at Taco John's. On December 18, 2006, the Minnesota Department of Health reported that 37 probable ... coli outbreak, nine people were confirmed ill with E. coli, eight people were hospitalized, and one person had developed ...
... in vitro translation and Escherichia coli cloning studies". Proceedings of the National Academy of Sciences of the United ... Coronaviruses evade innate immunity during the first ten days of viral infection. In the early stages of infection, SARS-CoV-2 ... although diagnosis early in infection is difficult since physical symptoms are sparse in early hepatitis C infection. Control ... Certain symptoms of infections, such as fever, muscle pain and "flu-like symptoms", are also caused by the production of IFNs ...
His dissertation is entitled, "Biochemical and genetic studies with spectinomycin in Escherichia coli." Anderson taught at ... is an American microbiologist best known for developing a vaccine that protects children from infections by Haemophilus ...
2008). "UpaG, a new member of the trimeric autotransporter family of adhesins in uropathogenic Escherichia coli". J Bacteriol. ... The process of infection is complicated. The invasive bacterium must overcome many barriers in order to infect its host, ... TAAs are just one of many methods bacteria use to infect their hosts, infection resulting in diseases such as pneumonia, sepsis ... found as a common cause of middle ear infections in humans. The structure of UspA1 also has a head domain at N-terminal domain ...
Czyz A, Los M, Wrobel B, Wegrzyn G (2001). "Inhibition of spontaneous induction of lambdoid prophages in Escherichia coli ... Barksdale L, Arden SB (1974). "Persisting bacteriophage infections, lysogeny, and phage conversions". Annual Review of ...
... have been isolated from this species that inhibit fungal growth and the development of bacteria such as Escherichia coli, ... It is also used against nausea and vomiting, parasitic infections, both cutaneous and subcutaneous, swelling, oedema and gout, ...
Escherichia coli, Salmonella, and Staphylococcus aureus are a few bacteria whose growth can be inhibited by alcohols. Alcohols ... "Antimicrobial surfaces to prevent healthcare-associated infections: a systematic review". Journal of Hospital Infection. 92 (1 ... to reduce the prevalence of Escherichia coli. Copper-alloy surfaces have natural intrinsic antimicrobial properties and can ... In medicine, they are used as a treatment for infections such as athlete's foot, ringworm and thrush and work by exploiting ...
Cholera and enterotoxigenic escherichia coli (ETEC) travellers' diarrhea vaccine: Canadian Immunization Guide. Health Canada ( ... cholera vaccine is widely used by backpackers and persons visiting locations where there is a high risk of cholera infection. ...
Bhatt S, Egan M, Jenkins V, Muche S, El-Fenej J (2016). "Escherichia coli". Frontiers in Cellular and Infection Microbiology. 6 ... "Identification of bacteriophage-encoded anti-sRNAs in pathogenic Escherichia coli". Molecular Cell. 55 (2): 199-213. doi: ... AsxR, previously known as EcOnc02, is an anti-sRNA encoded within the 3' region of the stx2B gene of E.Coli bacteria. It acts ... This aids bacterial infection of the animal host gut. AgvB, previously known as EcOnc01, inhibits GcvB sRNA repression. ...
"Engineering the Escherichia coli Fermentative Metabolism". In Cordes M, Wittmann C, Krull R (eds.). Biosystems Engineering II: ... Drugs that inhibit enzymes needed for the replication of viruses are effective in treating viral infections. Antiviral drugs ... de Leuw P, Stephan C (April 2018). "Protease inhibitor therapy for hepatitis C virus-infection". Expert Opinion on ... Infection. 49 (1): 29-56. doi:10.1007/s15010-020-01536-y. PMC 7851017. PMID 33367978. Mobley H (13 March 2006). "How do ...
Outside academia, he is best known as the chair of the Pennington Group enquiry into the Scottish Escherichia coli outbreak of ... Another case of E. coli infection occurred in Tayside in January 1997 and the group was tasked with investigating the ... In late November 1996, an Escherichia coli outbreak in the town of Wishaw prompted the Scottish Office to establish an expert ... 8 April 1997). "Annex 1". Report on the circumstances leading to the 1996 outbreak of infection with E.coli 0157 in Central ...
... particularly between TLR4 and NOD1 in response to Escherichia coli infection. Another proof of the cooperation and integration ... Since all types of PRRs play a role in the identification and eradication of the infection, their specific agonists mount a ... In a healthy individual Helicobacter pylori infection is targeted by the combination of PRRs, namely TLRs, NLRs, RLRs and CLR ... Burberry A, Zeng MY, Ding L, Wicks I, Inohara N, Morrison SJ, Núñez G (June 2014). "Infection mobilizes hematopoietic stem ...
"Potential effect of cattle diets on the transmission of pathogenic Escherichia coli to humans". Microbes and Infection / ... Escherichia coli, although considered to be part of the normal gut flora for many mammals (including humans), has many strains ... Also, the amount of E. coli they do have is much less likely to survive our first-line defense against infection: stomach acid ... coli becomes acid resistant. If humans ingest this acid-resistant E. coli via grain-feed beef, a large number of them may ...
Gram-negative aerobic microorganisms Haemophilus influenzae Moraxella catarrhalis Neisseria gonorrhoeae Escherichia coli ... Lower respiratory tract infections. Urinary tract infections. Skin and soft tissue infections. Gonorrhoea. Early Lyme disease. ... Cefuroxime axetil treats infections against methicillin, oxacillin and penicillin-sensitive bacterial strains. Cefuroxime ... Some medical uses are: Upper respiratory tract infections. ...
... coli, are human pathogens, and are the most common cause of urinary tract infections, significant sources of gastrointestinal ... The genus is named after Theodor Escherich, the discoverer of Escherichia coli. Escherichia are facultative aerobes, with both ... While E. coli is responsible for the vast majority of Escherichia-related pathogenesis, other members of the genus have also ... "The Species of Escherichia other than E. coli". The Prokaryotes. Retrieved 2006-05-05.[permanent dead link] Pien FD, Shrum S, ...
... independent inflammatory responses following infection by enteropathogenic Escherichia coli and Citrobacter rodentium". ... Infection and Immunity. 76 (4): 1410-22. doi:10.1128/IAI.01141-07. PMC 2292885. PMID 18227166. Kida Y, Inoue H, Shimizu T, ... Infection and Immunity. 75 (1): 164-74. doi:10.1128/IAI.01239-06. PMC 1828393. PMID 17043106. Gutzman JH, Rugowski DE, ... and bacterial and viral infections. AP-1 controls a number of cellular processes including differentiation, proliferation, and ...
Phage P4 infects Escherichia coli. It is a satellite virus which cannot engage in lytic growth without the presence of a P2- ... It generally follows a lysogenic life cycle: after infection, the P4 genome integrates into that of its host. The P4 genome can ... Enterobacteria phage P4 (also known as satellite phage P4) is a temperate bacteriophage strain of species Escherichia virus P2 ...
Bacterial membrane vesicles dispersion along the cell surface was measured in live Escherichia coli, commensal bacteria common ... contents and utilized as potent pathogen-free vaccines for immunizing humans and animals against threatening infections. Gram- ...
In Gram-negative bacteria, such as Escherichia coli, alkaline phosphatase is located in the periplasmic space, external to the ... Kidney tumors and infections as well as malnutrition have also shown abnormal level of alkaline phosphatase in blood. Alkaline ... In the laboratory, however, mutant Escherichia coli lacking alkaline phosphatase survive quite well, as do mutants unable to ... ISBN 978-0-470-08766-4. Rao NN, Torriani A (July 1990). "Molecular aspects of phosphate transport in Escherichia coli". ...
... as well preventing biofilm formation of Escherichia coli and Listeria monocytogenes. As of July 2020, the World Health ... Once easily-treatable conditions like urinary tract infections have become increasingly difficult to address as infection- ... In one of the earliest studies of endolysins as antibacterial therapy, oral streptococcus infections of mice were completely ... Other studies have demonstrated the efficacy of endolysins in combating infection by various Bacillus, Enterococcus, and ...
"Relationship of protein structure of isoleucyl-tRNA synthetase with pseudomonic acid resistance of Escherichia coli. A proposed ... Mupirocin is used as a topical treatment for bacterial skin infections (for example, boils, impetigo, or open wounds), which ... In E. coli IleRS, a single amino acid mutation was shown to alter mupirocin resistance. MuH is linked to the acquisition of a ... Mupirocin, sold under the brand name Bactroban among others, is a topical antibiotic useful against superficial skin infections ...
"Hypochlorous acid-promoted loss of metabolic energy in Escherichia coli". Infection and Immunity. 55 (10): 2518-25. doi:10.1128 ... "Differential effects of myeloperoxidase-derived oxidants on Escherichia coli DNA replication". Infection and Immunity. 66 (6): ... Strains of Escherichia coli and Vibrio cholerae lacking Hsp33 were rendered especially sensitive to HClO. Hsp33 protected many ... Albrich, JM; Hurst, JK (1982). "Oxidative inactivation of Escherichia coli by hypochlorous acid. Rates and differentiation of ...
Wilks, S.A.; Michels, H.; Keevil, C.W. (2005). "The survival of Escherichia coli O157 on a range of metal surfaces". ... In the US, the most frequent type of hospital infection is urinary tract infection (36%), followed by surgical site infection ( ... infections of surgery site (14.2%). Infections of the skin and mucous membrane (10.2%), other respiratory infections (6.8%) and ... Nosocomial infections can cause severe pneumonia and infections of the urinary tract, bloodstream and other parts of the body. ...
Intranasal administration of PGLYRP3 protects mice from lung infection with S. aureus and E. coli, but PGLYRP3-deficient mice ... Escherichia coli, Proteus vulgaris, Salmonella enterica, Shigella sonnei, Pseudomonas aeruginosa) bacteria. The mechanism of ... PGLYRP3 plays a limited role in host defense against infections. ...
... structure of Escherichia coli B glutathione synthetase complexed with ADP, glutathione, and sulfate at 2.0 A resolution". ... Cai J, Chen Y, Seth S, Furukawa S, Compans RW, Jones DP (Apr 2003). "Inhibition of influenza infection by glutathione". Free ... On the other hand, E. coli glutathione synthetase is a homotetramer. Nevertheless, they are part of the ATP-grasp superfamily, ... GSH is capable of preventing infection from the influenza virus. Patients with mutations in the GSS gene develop glutathione ...
"Iron induces bimodal population development by Escherichia coli". PNAS. 110 (7): 2629-2634. doi:10.1073/pnas.1218703110. PMC ... Delude, Cathryn Delude (May 28, 2002). "Culprit in ear infections is a 'biofilm' that protects bacteria". The Boston Globe. ... Sternberg, Steve (May 17, 1998). "The tooth of the matter: Dental infections implicated in other illnesses". Chicago Sun-Times ... catheter infections, oral health) Industrial systems and processes (biofouling, microbial corrosion, product contamination) ...
... s also play a significant role in bacterial adhesion, most notably in Escherichia coli. E. coli and other bacteria ... During this process, leukocytes move through the circulatory system to sites of infection, and in doing so they 'roll' and bind ... adhesion of type 1 fimbriated Escherichia coli". Molecular Microbiology. 53 (5): 1545-1557. doi:10.1111/j.1365-2958.2004.04226. ... Catch bonds are responsible for the failure of E. coli in the urinary tract to be eliminated during urination, thus leading to ...
First described in 1885, E coli has become recognized as both a harmless commensal and a versatile pathogen. ... Escherichia coli, a facultatively anaerobic gram-negative bacillus, is a major component of the normal intestinal flora and is ... encoded search term (Pediatric Escherichia Coli Infections) and Pediatric Escherichia Coli Infections What to Read Next on ... Pediatric Escherichia Coli Infections. Updated: Mar 19, 2019 * Author: Archana Chatterjee, MD, PhD; Chief Editor: Russell W ...
Enhanced Detection of Sporadic Escherichia coli O157:H7 Infections -- New Jersey, July 1994 Infection with Escherichia coli ... coli O157:H7 (1). This report describes the investigation of a pseudo-outbreak of E. coli O157:H7 infection that occurred in ... From June 1 through July 27, 1994, a total of 46 culture-confirmed cases of E. coli O157:H7 infection were reported to the New ... Escherichia coli O157:H7 outbreak linked to commercially distributed dry-cured salami -- Washington and California, 1994. MMWR ...
Prevention and control of enterohaemorrhagic escherichia coli (‎EHEC)‎ infections : report of a WHO Consultation, Geneva, ... WHO Consultation on Prevention and Control of Enterohaemorrhagic Escherichia Coli Infections (‎1997: Geneva, Switzerland)‎; ... We determined the prevalence of enterohaemorrhagic Escherichia coli, especially E. coli O157, and other enteropathogens among ... Enterohaemorrhagic Escherichia coli in raw beef and beef products: approaches for the provision of scientific advice: meeting ...
... -- New Jersey, July 1994 ... Laboratory screening for Escherichia coli O157:H7 -- Connecticut, 1993. MMWR 1994; 43:192-4. * CDC. Escherichia coli O157:H7 ... Infection with Escherichia coli O157:H7 causes an estimated 20,000 cases of diarrhea in the United States each year. Although E ... Enhanced Detection of Sporadic Escherichia coli O157:H7 Infections -- New Jersey, July 1994 MMWR 44(22);417-418 Publication ...
The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorrhagic E. coli, and the associated ... Shiga toxin--producing Escherichia coli (STEC) are a leading cause of bacterial enteric infections in the United States. Prompt ... Escherichia coli O157:H7 infections: discordance between filterable fecal Shiga toxin and disease outcome. J Infect Dis 2002; ... Escherichia coli O157:H7 infections: discordance between filterable fecal Shiga toxin and disease outcome. J Infect Dis 2002; ...
Escherichia coli (abbreviated as E. coli) are a large and diverse group of bacteria commonly found in the gut of humans and ... Enterohaemorrhagic Escherichia coli in Raw Beef and Beef Products: Approaches for the Provision of Scientific Advice: Meeting ... Faecal contamination of vegetables is one of the primary sources of E-coli infections. Photo credit: WHO ... Most strains of E. coli are harmless however, specific strains such as enterohaemorrhagic E. coli, can cause severe foodborne ...
From the editors: Controlling Escherichia coli O157 infections. Euro Surveill. 1998;2(42):pii=1139. ...
H7 Infections Linked to I.M. Healthy Brand SoyNut Butter ... Multistate Outbreak of Shiga toxin-producing Escherichia coli ... E. coli O157:H7 Infections Linked to Romaine Lettuceplus icon *E. coli O157:H7 Infections Linked to Romaine Lettuce en Español ... Outbreak of E. coli Infections Linked to Romaine Lettuceplus icon *E. coli O157:H7 Infections Linked to Romaine Lettuce en ... Timeline for Reporting Cases of E. coli O157 Infection. *2022 Outbreaksplus icon *E. coli Outbreak Linked to Frozen Falafelplus ...
Evaluation of phage therapy for the treatment of Escherichia coli and Pseudomonas aeruginosa burn wound infections (Phase I-II ... Hard-to-treat MDR Gram-negative bacteria such as Escherichia coli (E. coli) or Pseudomonas aeruginosa (P. aeruginosa) are ... Evaluation of phage therapy for the treatment of Escherichia coli and Pseudomonas aeruginosa burn wound infections (Phase I-II ... Only patients with a mono infection by E. coli or P. aeruginosa should be included in the trial;. - The impact of phages on ...
Global incidence of human Shiga toxin-producing Escherichia coli infections and deaths: a systematic review and knowledge ... Escherichia coli Infections / microbiology * Escherichia coli Infections / mortality * Escherichia coli Infections / prevention ... Objectives: Shiga toxin-producing Escherichia coli (STEC) are an important cause of foodborne disease, yet global estimates of ... Escherichia coli Infections / epidemiology* * ... Shiga-Toxigenic Escherichia coli / growth & development * Shiga ...
"Shiga toxin--producing Escherichia coli (STEC) are a leading cause of bacterial enteric infections in the United States. Prompt ... Title : Non-O157 Shiga toxin-producing Escherichia coli infections in Europe. Personal Author(s) : Caprioli, A.;Tozzi, A. E.; ... Hemolytic uremic syndrome surveillance to monitor trends in infection with Escherichia coli O157:H7 and other shiga toxin- ... Title : Hemolytic uremic syndrome surveillance to monitor trends in infection with Escherichia coli O157:H7 and other shiga ...
... coli urinary tract infections (UTI) are absent. This study systematically reviewed the literature and where appropriate, meta- ... Ciprofloxacin resistance in E. coli UTI is increasing and the use of this antimicrobial agent as empirical therapy for UTI ... Similarly, a significant rise in resistance over time was seen in studies reporting on community-acquired E. coli UTI. ... coli) to fluoroquinolones such as ciprofloxacin has increased. Systematic reviews of studies investigating ciprofloxacin ...
... coli. Risk factors for rectal colonization by ST131 Escherichia coli (irrespective of ESBL production) were investigated in 64 ... These results should be considered for infection control purposes. ... of 34 and 30 index patients with community and nosocomial infection due to these organisms, respectively, using multilevel ... Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades ...
... and other clinical infections such as neonatal meningitis and pneumonia. The genus Escherichia is named after Theodor Escherich ... Escherichia coli is one of the most frequent causes of many common bacterial infections, including cholecystitis, bacteremia, ... cholangitis, urinary tract infection (UTI), and travelers diarrhea, ... encoded search term (Escherichia coli (E coli) Infections) and Escherichia coli (E coli) Infections What to Read Next on ...
2022 The Journal of Infection in Developing Countries. ISSN: 1972-2680. Privacy Policy. ... Antibiotic resistance profile of commensal Escherichia coli isolated from healthy sheep in Qatar * Nahla O Eltai Biomedical ... Antibiotic resistance profile of commensal Escherichia coli isolated from healthy sheep in Qatar. J Infect Dev Ctries 14:138- ... Results: E. coli was isolated from 144 samples (84.2%), of which 90% were resistant to at least one antibiotic and 44% were ...
Results of search for su:{Escherichia coli infections} Refine your search. *. Availability. * Limit to currently available ... Escherichia coli O157:H7 and other shiga toxin-producing E. coli strains / editors: James B. Kaper, Alison D. OBrien. by Kaper ... Enterohaemorrhagic Escherichia coli in raw beef and beef products: approaches for the provision of scientific advice: meeting ... Escherichia coli : mechanisms of virulence / edited by Max Sussman. by Sussman, Max. ...
Percentage of bloodstream infections due to Escherichia coli,statefulURL:true,showLytebox:null,showShareOptions:true, ... showViewCount:false,viewCountThreshold:1,workbookName:Percentage of bloodstream infections due to Escherichia coli, ...
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Haemagglutinins & enterotoxins in Escherichia coli strains from human urinary tract infections.. Auteur(s): Saxena, V K. Yadava ... Haemagglutinins & enterotoxins in Escherichia coli strains from human urinary tract infections. Indian Journal of Medical ...
keywords = "Escherichia coli (E. coli), lab-on-a-chip (LOC), point-of-care testing, urinary tract infection (UTI)", ... that can separate and detect Escherichia coli (E. coli) in simulated urine samples for urinary tract infection (UTI) ... that can separate and detect Escherichia coli (E. coli) in simulated urine samples for urinary tract infection (UTI) ... that can separate and detect Escherichia coli (E. coli) in simulated urine samples for urinary tract infection (UTI) ...
Finished genome sequences are presented for four Escherichia coli strains isolated from bloodstream infections at San Francisco ... Complete genome sequences of four Escherichia coli ST95 isolates from bloodstream infections. Authors: Stephens, Craig M and ... Finished genome sequences are presented for four Escherichia coli strains isolated from bloodstream infections at San Francisco ...
Escherichia [‎2]‎. Escherichia coli [‎14]‎. Escherichia coli Infections [‎9]‎. Escherichia coli O157 [‎2]‎. ...
The incidence of E. coli infections was 5.4% and 2.0/1,000 patient-days. The occurrence of E. coli infections depended ... coli infection. Multivariate analysis demonstrated only one significant risk factor for E. coli infection among infants with a ... Infections in newborns remain one of the most significant problems in modern medicine. Escherichia coli is an important cause ... Mode of delivery and other risk factors for Escherichia coli infections in very low birth weight infants.. Chmielarczyk, ...
... and Shiga toxin-producing Escherichia coli (STEC) infections to community ... Estimating Community Incidence of Salmonella, Campylobacter, and Shiga Toxin-producing Escherichia coli Infections, Australia. ...
An E. Coli infection can make you feel sick. Learn about E. Coli symptoms, treatment, and more. ... E. Coli (National Institute of Allergy and Infectious Diseases) * E. Coli (Escherichia coli) (Centers for Disease Control and ... E-Coli Infection: Not Just from Food (American Academy of Pediatrics) Also in Spanish ... The primary NIH organization for research on E. Coli Infections is the National Institute of Allergy and Infectious Diseases ...
The incidence of true urinary tract infection (UTI) in adult males younger than 50 years is low (approximately 5-8 per year per ... Risk factors for fluoroquinolone-resistant Escherichia coli in adults with community-onset febrile urinary tract infection. J ... Risk factors for community-acquired ciprofloxacin-resistant Escherichia coli urinary tract infection. Ann Pharmacother. 2004 ... Prevalence and risk factor analysis of trimethoprim-sulfamethoxazole- and fluoroquinolone-resistant Escherichia coli infection ...
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  • E coli O157:H7 is the most virulent of the EHEC. (
  • Infection with Escherichia coli O157:H7 causes an estimated 20,000 cases of diarrhea in the United States each year. (
  • Although E. coli O157:H7 can be isolated using commercially available media, many clinical laboratories do not routinely test stool samples for the organism. (
  • In 1993, the Council of State and Territorial Epidemiologists recommended that clinical laboratories begin culturing all bloody stools -- and optimally all diarrheal stools -- for E. coli O157:H7 (1). (
  • This report describes the investigation of a pseudo-outbreak of E. coli O157:H7 infection that occurred in New Jersey during July 1994 after a year-long increase in the number of laboratories culturing all diarrheal specimens for this pathogen. (
  • From June 1 through July 27, 1994, a total of 46 culture-confirmed cases of E. coli O157:H7 infection were reported to the New Jersey Department of Health (NJDOH). (
  • A case was defined as a stool culture positive for E. coli O157:H7 in a New Jersey resident with onset of diarrhea during July 1994. (
  • This finding was verified by laboratory tests that identified 17 different strains of E. coli O157:H7 among the 23 clinical isolates. (
  • To assess the role of enhanced laboratory surveillance in generating the increase in case reports, NJDOH surveyed 20 clinical laboratories that had reported at least one E. coli O157:H7 isolate during 1994. (
  • The number of laboratories culturing all diarrheal specimens for E. coli O157:H7 had increased from two (10%) in July 1993 to 18 (90%) in July 1994. (
  • Editorial Note: Since 1993, several outbreaks of E. coli O157:H7 infection have been detected as a result of increased laboratory testing for this organism (2,3). (
  • A primary strategy for preventing infection with E. coli O157:H7 is reducing risk behaviors through consumer education. (
  • In New Jersey, the sudden increase in E. coli O157:H7 case reports was reported widely by the news media. (
  • Although traceback investigations can be important in preventing E. coli O157:H7 infections, they should be undertaken selectively. (
  • An effective public health response to E. coli O157:H7 requires a timely and sensitive national surveillance system. (
  • Through March 1995, a total of 33 states had enacted legislation designating E. coli O157:H7 infection as a reportable disease (W. Keene, State Health Division, Oregon Department of Human Resources, personal communication, 1995). (
  • Most reported STEC infections in the United States are caused by E. coli O157:H7, with an estimated 73,000 cases occurring each year ( 2 ). (
  • Escherichia coli O157:H7 and other shiga toxin-producing E. coli strains / editors: James B. Kaper, Alison D. O'Brien. (
  • Since STEC was linked with hemorrhagic colitis in 1982 ( 2 ) , strains-particularly serotype O157:H7-have been associated with numerous outbreaks and many sporadic cases of infections worldwide. (
  • serotype O157:H7 has not been previously isolated from human infections in our country. (
  • The most common cause of HUS is infection with a strain of Escherichia coli (E. coli) bacterium called E. coli O157:H7 , although other bacteria and viruses may also cause this condition. (
  • Genomewide transcriptional response of Escherichia coli O157:H7 to norepinephrine. (
  • Specifically, E coli serotype O157:H7 has been associated with more than 80% of infections leading to HUS. (
  • In contrast to the essential and beneficial role of most E coli isolates in the human intestine, pathogenic E coli are responsible for a broad spectrum of human disease. (
  • The presence of genes for verotoxin 1 and 2 [‎VT1 and 2]‎ among sorbitol non-fermenting Escherichia coli isolates from diarrhoeal cases was assessed using polymerase chain reaction assay. (
  • Complete genome sequences of four Escherichia coli ST95 isolates from bloodstream infections. (
  • Escherichia coli isolates from different diagnostic specimens including blood , tracheal/bronchial secretions and others were collected. (
  • Among E. coli isolates, 17.7% were classified as multidrug resistant. (
  • Escherichia coli isolates showed different pulsotypes and dominant epidemic clones were not detected. (
  • Antimicrobial resistance profiles in Escherichia coli O157 isolates from northern Colorado dairies. (
  • In this study, 90 isolates of esbl-e. coli isolated from patients with urinary tract infections were identified via biochemical and bacteriological methods. (
  • The mics range of vancomycin and trimethoprim against esbl-e. coli were 8-256 and 1-64 μg/ml, respectively, while for vancomycin in combination with trimethoprim was ranged from 0.128 to 8 μg/ml. indeed, the combination therapy of vancomycin/trimethoprim was exerted the synergistic effects in esbls producing isolates with fractional inhibitory concentration index ranged from 0.281 to 1.5. (
  • due to high risk factor of the β-lactamase producing isolates in uti infections, further studies are suggested to prevent their spread in community. (
  • In Nigeria, studies on the prevalence and antimicrobial susceptibility patterns of clinical isolates from urinary tract infections are inadequate. (
  • Employing standardised microbiological methods, this study assessed the prevalence and antimicrobial susceptibility patterns of E. coli isolates from UTI in University of Maiduguri Teaching Hospital (a tertiary health care institution) in North Eastern, Nigeria. (
  • Uropathogenic E. coli (UPEC) accounted for 150 (62.50%) of 240 urine isolates. (
  • Methods We conducted unselected, population-level genomic surveillance of bloodstream E. coli and Klebsiella pneumoniae isolates from 2008-2018 in Oxfordshire, UK. (
  • Results We sequenced 3478 E. coli isolates (3278 passed quality control) and 556 K. pneumoniae isolates (535 (K-antigen) and 549 (O-antigen) passed quality control). (
  • For E. coli, based on serotyping, the ExPEC4V and ExPEC10V vaccines under investigation would cover 46% and 72% of Oxfordshire isolates respectively, and 47% and 71% of MDR isolates. (
  • Despite the low number of isolates examined, this is the first study correlating these characteristics in lactose-negative E. coli isolates. (
  • A total of 52 Escherichia coli isolates, 20 from stock and 32 directly isolated from cases of avian colibacillosis. (
  • All the 52 (100%) E. coli isolates were susceptible to Cefixime. (
  • Hemolytic-uremic syndrome (HUS) is a potentially devastating consequence of enteric infection with specific E coli strains. (
  • Most strains of E. coli are harmless however, specific strains such as enterohaemorrhagic E. coli , can cause severe foodborne disease. (
  • IMSEAR at SEARO: Haemagglutinins & enterotoxins in Escherichia coli strains from human urinary tract infections. (
  • Finished genome sequences are presented for four Escherichia coli strains isolated from bloodstream infections at San Francisco General Hospital. (
  • escherichia coli atcc 25922 as a reference quality-control strains was employed. (
  • Antimicrobial resistance in Esherichia coli strains from urinary tract infections. (
  • Although many genetic lineages and strains of E coli can be found in dogs and cats, 1,2 some strains are shared among dogs, cats, and humans. (
  • Shiga toxin-producing Escherichia coli (STEC) strains are associated with a spectrum of diseases ranging from mild to severe bloody diarrhea and complications such as hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura ( 1 ) . (
  • Although most sporadic cases and outbreaks have been reported from developed countries, human infections associated with STEC strains have also been described in Latin American countries, including Argentina and Chile ( 3 ) . (
  • The first strain was identified among a laboratory collection of 2,573 E. coli strains that were retrospectively analysed and isolated from patients with diarrhea in São Paulo State, from 1976 through 1999, at the Central Laboratory of Instituto Adolfo Lutz (IAL). (
  • The strains, isolated by routine diagnostic procedures on MacConkey agar plates, were presumptively identified as E. coli O157 by standard methods with specific O157 antiserum. (
  • These last two strains were confirmed as sorbitol-negative E. coli O157 at the IAL Regional Laboratory at Campinas and were sent to the IAL Central Laboratory for further characterization. (
  • The three O157 E. coli strains underwent biochemical identification and serotyping by standard methods. (
  • To date, no studies have examined the potential relationship between biochemical characteristics and quinolone resistance in uropathogenic E. coli strains. (
  • The present work analyzed the quinolone sensitivity and biochemical activities of fifty-eight lactose-negative uropathogenic E. coli strains. (
  • However, some specific strains of E. coli , passed on through contaminated food, are responsible for infections that can lead to HUS. (
  • CIPRO XR is indicated only for the treatment of urinary tract infections, including acute uncomplicated pyelonephritis, caused by susceptible strains of the designated microorganisms as listed below. (
  • and Pseudomonas aeruginosa , common in respiratory infections. (
  • Sefdin 300 Mg is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiellapneumoniae. (
  • Complicated Urinary Tract Infections caused by Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, Proteus mirabilis, or Pseudomonas aeruginosa a . (
  • Staphylococcus aureus , Escherichia coli , Pseudomonas aeruginosa and Bacillus subtilis causing infections in human beings. (
  • As many important pathogenic bacteria produce curli or curli-like amyloids in their biofilms, including Escherichia coli , Staphylococcus aureus and Pseudomonas aeruginosa , this novel immunotherapy has the potential to be applied to a wide variety of infections. (
  • In the case of ciprofloxacin therapy in a Salmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium, S. Tm) mouse infection model, this has been traced to tolerant bacterial cells surviving in lymph node monocytes (i.e., classical dendritic cells). (
  • Resistance to bile salts permits that certain bile-resistant pathogens can colonize the hepatobiliary tract, and an outstanding example is the chronic infection of the gall bladder by Salmonella enterica . (
  • salmonella foodborne intoxication and infection (A02. (
  • The incidence of Shiga toxin-producing Escherichia coli (STEC) O157 and Salmonella enterica serotype Typhimurium infections declined in 2014 compared with 2006-2008, and the incidence of infection with Campylobacter, Vibrio , and Salmonella serotypes Infantis and Javiana was higher. (
  • Compared with 2011-2013, the incidence of STEC O157 and Salmonella Typhimurium infections was lower, and the incidence of STEC non-O157 and Salmonella serotype Infantis infections was higher in 2014. (
  • FoodNet conducts active, population-based surveillance for laboratory-confirmed infections caused by Campylobacter , Cryptosporidium , Cyclospora , Listeria , Salmonella , Shiga toxin-producing Escherichia coli (STEC) O157 and non-O157, Shigella , Vibrio , and Yersinia in 10 geographic areas covering approximately 15% of the U.S. population (an estimated 48 million persons in 2013). (
  • The Stool Culture Test is used to detect the presence of disease causing bacterial organisms including Salmonella, Shigella, Campylobacter, and Shiga toxin (if detected, Escherichia coli O157, Culture will be performed) in the stool and aid in the diagnosis of Typhoid Fever, Enteric Fever, Bacillary Dysentery, and Salmonella infection. (
  • Everyone is susceptible to infection by Salmonella spp. (
  • Infections by Salmonella spp. (
  • EHEC, also known as Shiga-toxin producing E coli (STEC), induces an attaching and effacing (AE) lesion in the large bowel. (
  • Prompt, accurate diagnosis of STEC infection is important because appropriate treatment early in the course of infection might decrease the risk for serious complications such as renal damage and improve overall patient outcome. (
  • and clinical considerations and recommendations for management of patients with STEC infection. (
  • Improving the diagnostic accuracy of STEC infection by clinical laboratories should ensure prompt diagnosis and treatment of these infections in patients and increase detection of STEC outbreaks in the community. (
  • Shiga toxin--producing E. coli (STEC) cause approximately 100,000 illnesses, 3,000 hospitalizations, and 90 deaths annually in the United States, according to the last estimate in 1999 ( 2 ). (
  • In the United States, six non-O157 serogroups (O26, O45, O103, O111, O121, and O145) account for the majority of reported non-O157 STEC infections ( 5 ). (
  • STEC that cause human illness are also referred to as enterohemorrhagic E. coli . (
  • In this report, all E. coli that produce a Shiga toxin are referred to as STEC. (
  • Shiga toxin-producing E. coli (STEC) is an important cause of illness in the United States. (
  • Shiga toxin-producing Escherichia coli (STEC) are an important cause of foodborne disease, yet global estimates of disease burden do not exist. (
  • HUS is most often triggered by Shiga toxin-producing Escherichia coli (STEC) infection, in particular by a type of STEC called O157. (
  • About 80% of pediatric patients (children younger than 18) who develop HUS have STEC infection. (
  • Public health officials around the world are watching what they hope is the final stage of a massive outbreak of Shiga toxin-producing Escherichia coli (STEC) infections that began in Germany in May. (
  • This life-threatening outcome of STEC infection is uncommon, developing in 5-10% of cases. (
  • Studies of human genetics and HUS have focused mostly on a rare form of the disease that runs in families and is not associated with STEC infection. (
  • Recent research, however, suggests that most people who develop HUS-whether related to STEC infection or not-may have variants in genes associated with the clotting and complement pathways. (
  • FoodNet has incorporated human genetics into an epidemiologic study of risk factors for HUS in persons with STEC infection. (
  • Typical HUS is related to bacteria, with more than 90% following a gastrointestinal infection with Shiga toxin-producing Escherichia coli (STEC). (
  • Surveillance for physician-diagnosed postdiarrheal hemolytic uremic syndrome, a complication of STEC infection characterized by renal failure, thrombocytopenia, and microangiopathic hemolytic anemia, is conducted through a network of nephrologists and infection preventionists and by hospital discharge data review. (
  • Non-O157 Shiga toxin-producing Escherichia coli infections in Europe. (
  • Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany. (
  • The Shiga toxin-producing Escherichia coli O157 strain is estimated to cause 73,000 illnesses annually in the United States alone, with approximately 2,000 causes requiring hospitalization. (
  • Escherichia coli (abbreviated as E. coli ) are a large and diverse group of bacteria commonly found in the gut of humans and warm-blooded animals. (
  • A recent World Health Organisation (WHO) report on antimicrobial resistance (AMR) surveillance specified nine bacteria of international concern which are responsible for some of the most common infections in community and hospital settings [ 3 ]. (
  • They should therefore be used with caution and reserved for severe infections, and preceded by antimicrobial susceptibility testing of the bacteria involved [ 5 ]. (
  • E. coli is the name of a type of bacteria that lives in your intestines. (
  • You can get E. coli infections by eating foods containing the bacteria. (
  • This report highlights the untapped resource of bacteria-specific small molecules as potential vaccine antigens and provides a proof of principle for incorporating these compounds into multicomponent vaccines for the prevention of bacterial infections. (
  • Known as persisters, these bacteria are probably the cause of relapsing infections such as typhoid fever. (
  • Antimicrobial susceptibility pattern of pathogenic bacteria causing urinary tract infections at the Specialist Hospital, Yola, Adamawa State, Nigeria. (
  • Gram-negative bacteria such as Escherichia coli or Klebsiella spp. (
  • Similar to other gram-negative bacteria, cell walls of E coli contain endotoxin, a pyrogenic toxin that can be associated with severe disease (eg, septic shock). (
  • In the secretion of the Phyllomedusa hypocondrialis , they identified peptides (protein fragments) capable of eliminating bacteria that cause diarrhea or hospital infections and even bring blood pressure down. (
  • Bladder infections often occur when bacteria get into the urethra, the tube that carries urine out of the body, and then move into the bladder. (
  • The bacteria can also move from the bladder into the kidneys, resulting in a kidney infection . (
  • Because females' urethrae are closer to their rectum than males' are, there is a shorter distance for bacteria to travel and cause infection. (
  • The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) says that diet, nutrition, and eating habits will not likely aid in the prevention of bladder infections, but drinking fluids to flush bacteria out of the urinary tract might. (
  • A better understanding of the interactions between bacteria and bile salts may inspire novel therapeutic strategies for gastrointestinal and hepatobiliary diseases that involve microbiome alteration, as well as novel schemes against bacterial infections. (
  • In fact, E. coli bacteria are normally found in the intestines of healthy people and animals. (
  • Bacteria cause urinary tract infections (UTIs), so doctors usually treat them with antibiotics. (
  • The most common cause of UTIs is the bacteria Escherichia coli . (
  • Antibiotics are the standard treatment for UTIs because they kill the bacteria responsible for the infections. (
  • According to research , antibiotics may destroy some of these bacteria, potentially increasing the likelihood of other infections. (
  • Infections with bacteria of the species ESCHERICHIA COLI . (
  • If the infection progresses, bacteria may invade the bloodstream, resulting in bacteremia. (
  • 201010 and the used of specific bacteria, as Staphylococcus aureus ATCC 6538P and Escherichia coli ATCC 8739. (
  • Although E. coli is most commonly associated with contaminated meat, scientists believe that in this case, it's possible that the bacteria hitched a ride on the restaurant chain's lettuce, onions, tomatoes or spices. (
  • Among gram negative bacteria, highest inhibitory effect was observed with P. aeruginosa followed by E. coli . (
  • Enteropathogenic Escherichia coli (EPEC) is a pathogenic bacteria causes acute gastroenteritis and colibacillosis in animals. (
  • The most common bacteria was Escherichia coli in both groups. (
  • Mixed Gram-positive and negative bacteria with Escherichia coli were the most common bacteria in CD and cDC. (
  • Researchers have shown that a new therapeutic antibody can break apart communities of harmful bacteria , potentially opening the way for bacteria-killing antibiotics to more effectively clear out infections. (
  • MATERIALS & METHODS: We used stable bioluminescent bacteria and a low light imaging system to follow the progress of the infection noninvasively in real time. (
  • Uncomplicated Urinary Tract Infections (Acute Cystitis) caused by Escherichia coli, Proteus mirabilis, Enterococcus faecalis , or Staphylococcus saprophyticus a . (
  • We conduct an array of evidence-generating activities to inform international prevention and treatment policy of specific enteric infections including literature reviews challenging current management guidelines for Shigella infections, household Cryptosporidium transmission studies, and clinical trials testing the feasibility of integrated approaches to eliminating soil-transmitted helminths. (
  • The diabetic patient is also at an increased risk for infection as certain microorganisms become more virulent in a high glucose environment [4]. (
  • Isolated E. coli were tested for antibiotic susceptibility against 16 clinically- relevant antibiotics using the E-test method. (
  • Knowledge of the key mechanisms underlying the age-dependent susceptibility of the neonates to E. coli K1 could identify novel therapeutic targets. (
  • Antibiotics Susceptibility Patterns of some Uropathogens to Nitrofurantoin and Nalidixic Acid among Pregnant Women with Urinary Tract Infections in Federal Medical Centre, Bida, Niger-State, North Central, Nigeria. (
  • Prevalence and Antibiotic Susceptibility Pattern of E. coli Isolated from Urinary Tract Infection in Patients with Renal Failure Disease and Renal Transplant Recipients. (
  • Although cecal ligation and puncture represents a clinically relevant sepsis model, we wanted to test whether injury might also lead to greater susceptibility to peritoneal infection caused by a single common pathogen, Escherichia coli . (
  • Although E coli is the leading cause of bacterial cystitis, this bacterium can also be found in patients without classical clinical signs of lower urinary tract disease (ie, subclinical bacteriuria), making interpretation of culture and susceptibility results challenging. (
  • Figure 1: Susceptibility of protease-deficient mice to bacterial and fungal infection. (
  • Appropriate culture and susceptibility tests should be performed before treatment in order to isolate and identify organisms causing infection and to determine their susceptibility to ciprofloxacin. (
  • Escherichia coli is an important cause of neonatal bloodstream and respiratory tract infections and is associated with high mortality . (
  • The worst type of E. coli causes bloody diarrhea, and can sometimes cause kidney failure and even death. (
  • [ 46 ] However, another study revealed that absence of diarrhea does not rule out the severity of the C difficile infections and the risk of developing toxic megacolon. (
  • This test is most commonly used to aid in the diagnosis of digestive tract infection when someone is experiencing chronic diarrhea. (
  • The incidence of E. coli infections was 5.4% and 2.0/1,000 patient -days. (
  • We calculated a uniform weighted mean incidence of serious infections caused by antibiotic-susceptible E coli and K pneumoniae using data from 17 countries. (
  • Using this uniform incidence, as well as population sizes and country-specific resistance levels, we estimated the number of infections caused by third-generation cephalosporin-resistant and carbapenem-resistant E coli and K pneumoniae in 193 countries in 2014. (
  • We also calculated interval estimates derived from changing the fixed incidence of susceptible infections to 1 SD below and above the weighted mean. (
  • Abstract Background The incidence of bloodstream infections (BSIs) caused by Escherichia coli and Klebsiella pneumoniae is increasing, with substantial associated morbidity, mortality and antimicrobial resistance. (
  • these infections primarily affect women, pregnants and elderly people ( Foxman, 2002 Foxman B (2002) Epidemiology of Urinary Tract Infections: Incidence, Morbidity, and Economic Costs. (
  • Inter-epidemic Rift Valley fever virus infection incidence and risks for zoonotic spillover in northern Tanzania. (
  • In 10 U.S. geographic areas, the Foodborne Diseases Active Surveillance Network* (FoodNet) monitors the incidence of laboratory-confirmed infections caused by nine pathogens transmitted commonly through food. (
  • Despite ongoing food safety efforts, the incidence of many infections remains high, indicating that further prevention measures are needed to make food safer and achieve national health objectives. (
  • Incidence was calculated by dividing the number of laboratory-confirmed infections in 2014 by U.S. Census estimates of the surveillance area population for 2013. (
  • Change in the combined overall incidence of infection with six key foodborne p athogens § was estimated. (
  • Antimicrobial resistance (AMR) is a complex phenomenon that complicates the treatment of serious bacterial infections and is of increasing concern. (
  • Conclusions O-antigen targeted vaccines may be useful in reducing the morbidity, mortality and antimicrobial resistance associated with E. coli and K. pneumoniae BSIs. (
  • 2009) The ARESC study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections. (
  • Antimicrobial resistance is currently a very big global problem, initially reported in human patients but it has spread to the animal population, making it a very serious risk due to rampart difficult to treat microbial infections. (
  • The most recent Infectious Diseases Society of America (IDSA) guidelines recommend that fluoroquinolones should be reserved for important uses due to their propensity for ecological unfavorable effects of antimicrobial therapy such as the selection of drug-resistant pathogens and colonisation or infection with multidrug-resistant organisms [ 9 ]. (
  • We estimated the number of infections worldwide that are caused by the WHO priority pathogens third-generation cephalosporin-resistant and carbapenem-resistant Escherichia coli and Klebsiella pneumoniae. (
  • To our knowledge, this study is the first to report estimates of the global number of infections caused by antibiotic-resistant priority pathogens. (
  • Escherichia coli is the main agent of UTIs, especially in community-acquired UTIs, and quinolones and fluoroquinolones have been used extensively to treat these infections ( Ronald, 2003 Ronald A (2003) The etiology of urinary tract infection: traditional and emerging pathogens. (
  • And E. Coli is just one of many bacterial pathogens that collectively cost Americans more than $52 billion annually. (
  • Tetracyclines remain especially useful in the management of infections by certain obligately intracellular bacterial pathogens such as Chlamydia , Mycoplasma , and Rickettsia . (
  • Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. (
  • This study aims to test this hypothesis in an effort to define carbapenem-sparing alternatives for these infections.The study will use a multicentre randomised controlled open-label non-inferiority trial design comparing two treatments, meropenem (standard arm) and piperacillin-tazobactam (carbapenem-sparing arm) in adult patients with bacteraemia caused by E. coli or Klebsiella spp. (
  • And Lactose fermenting organisms were Escherichia coli, Enterobacteria spp and Klebsiella spp. (
  • The characteristic serotype of this pathogenic E coli displays the K1 antigen, which is responsible for 40% of the cases of bacteremia and 80% of the cases of meningitis caused by E coli . (
  • Escherichia coli O157 remains a substantial public health challenge worldwide, particularly because of its association with hemolytic uremic syndrome (HUS) ( 1 , 2 ). (
  • Hemolytic uremic syndrome (HUS) is a complex condition where an immune reaction, most commonly after a gastrointestinal tract infection, causes low red blood cell levels, low platelet levels, and kidney injury. (
  • The most severe E. coli infections can cause hemolytic uremic syndrome, a life-threatening condition that requires IV fluids, blood transfusions and kidney dialysis. (
  • E coli is also a commonly identified cause of urinary tract infections (UTIs) , as well as neonatal sepsis and meningitis. (
  • This study systematically reviewed the literature and where appropriate, meta-analysed studies investigating ciprofloxacin resistance in community- and hospital-acquired E. coli UTIs. (
  • Escherichia coli ( E. coli) , the pathogen most often implicated in UTIs, is listed as one of the nine. (
  • As a general rule, all urinary tract infections (UTIs) in men are considered complicated. (
  • Abstract Uropathogenic Escherichia coli (UPEC) is the primary cause of uncomplicated urinary tract infections (UTIs). (
  • Whereas most infections are isolated cases, 1 in 40 women experience recurrent UTIs. (
  • Both the physical and financial burdens of urinary tract infections (UTIs) are staggering. (
  • Uropathogenic Escherichia coli (UPEC) is a subclass of extraintestinal pathogenic E. coli (ExPEC) and is the etiological agent for 80% of all uncomplicated UTIs (1). (
  • UTIs are among the most common bacterial infections in the United States. (
  • For instance, research suggests that about 22% of females receiving treatment for uncomplicated UTIs develop a Candida vaginal infection, a type of fungal infection. (
  • According to some research , several species of E. coli , the primary cause of UTIs, show increasing drug resistance. (
  • Complicated urinary tract infections (UTIs) occur in the setting of pre-existing metabolic, functional, or structural abnormalities of the urinary tract. (
  • This paper describes a fatal case of pneumonia in a 14-day-old dog caused by extraintestinal pathogenic Escherichia coli (ExPEC). (
  • Given the importance of resistance in E. coli pathotypes, 2016;213:172-83. (
  • infections and assess the effects of resistance on disease. (
  • During the last decade the resistance rate of urinary Escherichia coli ( E. coli ) to fluoroquinolones such as ciprofloxacin has increased. (
  • Systematic reviews of studies investigating ciprofloxacin resistance in community- and hospital-acquired E. coli urinary tract infections (UTI) are absent. (
  • Similarly, a significant rise in resistance over time was seen in studies reporting on community-acquired E. coli UTI. (
  • Ciprofloxacin resistance in E. coli UTI is increasing and the use of this antimicrobial agent as empirical therapy for UTI should be reconsidered. (
  • The clinical impact of fluoroquinolone resistance in patients with E coli bacteremia. (
  • Relationship between hospital antibiotic use and quinolone resistance in Escherichia coli. (
  • The aim of our study was to investigate the epidemiology of E. coli infection in Polish neonatal intensive care units (NICUs) and resistance to antibiotics , with particular reference to the safety of very low birth weight infants . (
  • The antibiotic courses required to treat infections promote antibiotic resistance, and current vaccine options offer limited protection. (
  • We analyzed the association between antibiotic resistance and recurrent urinary tract infection (rUTI) by Escherichia coli. (
  • High rates of antibiotic resistance to the usual antibiotics was observed in E. coli causing UTI, with female sex, age, and antibiotic resistance being risk factors for the development of rUTI. (
  • Extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae are an increasing concern regarding antibiotic resistance and their potential to cause serious infections which are difficult to treat. (
  • Escherichia coli ( E. coli ) has been identified as the most common uropathogenic bacterial pathogen with increasing resistance to antibiotics. (
  • The microaerobic mucin-producing VDC system will facilitate investigations into the mechanisms underpinning colonization resistance and aid the development of microbiota-based anti-infection strategies. (
  • E coli is intrinsically susceptible to a wide range of antimicrobials ( Table 2 ), but acquired resistance and resistance from narrow spectrum beta-lactamase production are common. (
  • Complete genome sequence of Escherichia coli Antibiotic-Resistance Isolate AR Bank #0346. (
  • Results showed that there is high drug resistance of E. coli causing colibacillosis cases in chicken. (
  • Escherichia coli, a facultatively anaerobic gram-negative bacillus, is a major component of the normal intestinal flora and is ubiquitous in the human environment. (
  • Investigations with chicks show Astragalus to significantly increase beneficial Lactobacilli and Bacillus cereus numbers, while decreasing Escherichia coli numbers and lymphocyte responsiveness. (
  • Here, we have developed a microaerobic, mucus-producing vertical diffusion chamber (VDC) model and determined the influence of Limosilactobacillus reuteri and Ruminococcus gnavus on enteropathogenic E. coli (EPEC) infection. (
  • Enteropathogenic Escherichia coli (EPEC) merupakan bakteri patogen penyebab gastroenteritis akut dan kolibasillosis pada hewan. (
  • Everyone is susceptible to all forms of infection from E. coli, but EPEC is most commonly associated with infants, and all types tend to result in more severe symptoms in the very young and elderly. (
  • Our team is leading a multi-country network of clinical research centers from Sub-Saharan Africa, South East Asia, the UK, and the USA dedicated to identifying risk factors that increase mortality, hospital readmission, and poor recovery in children who are malnourished and suffering from acute infection. (
  • Predictive factors for acute renal cortial scintigraphic lesion and ultimate scar formation in youngsters with first febrile urinary tract an infection. (
  • Acute respiratory infections particularly clinical pneumonia are one of the most common causes of death world-wide. (
  • Escherichia coli : mechanisms of virulence / edited by Max Sussman. (
  • E coli can be classified into groups (including enteropathogenic, enterotoxigenic, enterohemorrhagic, adherent invasive, and uropathogenic) based on the presence of various virulence mechanisms. (
  • Detecting specific virulence factors may be useful, but the range of potential virulence factors and diseases is not adequately understood, and E coli with disease-associated virulence genes can be found in healthy patients. (
  • Fosfomycin (dogs only) and nitrofurantoin can be used to treat bacterial cystitis caused by multidrug-resistant E coli . (
  • Study background: Multidrug resistant Escherichia coli (MDR E. coli) has become a major health concern, and failure of treatment leads to huge health burden. (
  • Siderophore Vaccine Conjugates Protect Against Uropathogenic Escherichia Coli Urinary Tract Infection. (
  • Quinolones and fluoroquinolones are widely used to treat uropathogenic Escherichia coli infections. (
  • Catheterization also resulted in hypersensitivity to Enterococcus faecalis and uropathogenic Escherichia coli (UPEC) infection, in which colonization was achieved using an inoculum 100-fold lower than the ID90 for infection of an undamaged urothelium with the same uropathogens. (
  • Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses. (
  • German outbreak of Escherichia coli O104:H4 associated with sprouts. (
  • Secondary symptomatic or primary symptomatic laboratory-confirmed Escherichia coli O157 cases, by outbreak or sporadic occurence, Scotland, 1984-2008. (
  • Chipotle Mexican Grill Inc has closed all 43 of its restaurants in and around Portland and Seattle as it struggles to contain an E. coli outbreak. (
  • Escherichia coli is the most common gram-negative pathogenic bacterium causing meningitis. (
  • Escherichia coli is a gram-negative bacterium in the Enterobacterales order and is commonly found in the GI tract and the environment. (
  • Escherichia coli is a gram-negative rod that is found as a normal commensal in the GI tract, which can produce ocular infection including corneal ulcer and endophthalmitis, which can result in a devastating outcome. (
  • As the time of catheterization increased, however, colonization by the Gram-positive uropathogen E. faecalis was reduced, whereas catheterization created a sustained window of vulnerability to infection for Gram-negative UPEC over time. (
  • Escherichia coli are gram-negative non-spore forming bacilli that grow aerobically or anaerobically and may be variable in size and shape. (
  • First described in 1885, E coli has become recognized as both a harmless commensal and a versatile pathogen. (
  • 대장균은 그람 음성, 장내 세균과, 통성 혐기성, 간균으로, 임상 증상과 유전적 특징에 따라 공생균(commensal E. coli ), 장 내 병원성 대장균(intestinal pathogenic E. coli ), 장외 병원성 대장균(ExPEC, extraintestinal pathogenic E. coli )으로 분류할 수 있다[ 1 ]. (
  • Infections of the gastrointestinal tract (your stomach and intestines) are the most common cause of this syndrome. (
  • Therapeutic options for postoperative infection in gastrointestinal surgery are limited. (
  • We determined the prevalence of enterohaemorrhagic Escherichia coli, especially E. coli O157, and other enteropathogens among 200 children with bloody diarrhoea and 100 age-matched controls at two Baghdad hospitals. (
  • Enteropathogenic Escherichia coli. (
  • 장내 병원성 대장균은 병원형에 따라 장병원성대장균(enteropathogenic E. coli ), 장출혈성대장균(enterohemorrhagic E. coli ), 장독소성대장균(enterotoxigenic E. coli ), 장침입성대장균(enteroinvasive E. coli ), 장관흡착성대장균(enteroaggregative E. coli ), 광범위부착성대장균(diffusely adherent E. coli ), 괴사소성대장균(necrotoxigenic E. coli ), 장부착침투성대장균(adherent invasive E. coli ), 세포분리성대장균(cell-detaching E. coli )으로 분류된다[ 1 ]. (
  • Definitive diagnosis is likely in cases in which E coli is isolated from a normally sterile site (eg, blood) or E coli is found at sites where it is not normally present and there are supportive clinical and cytologic findings (eg, isolation from the lower airways in a patient with septic changes on bronchoalveolar lavage cytology). (
  • 4-9 Clinical signs and other urinalysis results are important for determining the clinical relevance of E coli isolation. (
  • Clinical observation suggests ESBL-producing E coli are typically susceptible to a limited range of drugs, particularly amikacin and meropenem. (
  • My work on these infections includes disease burden estimation, evaluation of new diagnostics, clinical management studies, risk factor research aimed at prevention interventions, and economic assessments. (
  • Within clinical trials, we are testing whether empiric use of a broad-spectrum antibiotic improves post-infection survival in Kenyan children. (
  • To identify new treatment alternatives, the Japan Society for Surgical Infection conducted a multicenter prospective, randomized, controlled clinical trial comparing the efficacy of intravenous ciprofloxacin (CIP IV) and intravenous meropenem (MEM IV). (
  • CONCLUSION: These data suggest that cationic fullerenes have clinical potential as an antimicrobial photosensitizer for superficial infections where red light is not needed to penetrate tissue. (
  • According to the World Health Organization in 2020, from all hospitalized patients, a share of cases are infections acquired in a hospital environment due to invasive procedures. (
  • Voriconazole in the treatment of aspergillosis, scedosporiosis and other invasive fungal infections in children. (
  • are a leading cause of bacterial enteric infections in the United States. (
  • The gut microbiota plays a crucial role in protecting against enteric infection. (
  • Enteric disease is the most challenging to diagnose, as E coli is a common enteric organism found in many healthy dogs. (
  • malnutrition is a serious consequence of enteric and diarrheal disease and undernourished children experience a higher risk of death after infection. (
  • Specific bacterial and parasitic enteric infections contribute a disproportionate burden to diarrheal disease, malnutrition, and poor academic performance. (
  • Uropathogenic E coli (UPEC) has the ability to colonize the uroepithelium by means of surface fimbriae. (
  • Although large outbreaks have occurred ( 7 , 8 ), most infections in Scotland are apparently sporadic ( 14 ) ( Figure 2 ). (
  • Our understanding of many aspects of disease pathogenesis has been acquired through the use of a robust neonatal rat model of E. coli K1 systemic infection. (
  • These results indicate that the E. coli K1 systemic infection is a multi-factorial process. (
  • This case was confirmed to have fatal pneumonia caused by ExPEC that led to a systemic infection. (
  • Evidence was found suggesting that the middle small intestine of susceptible animals may be the site where E. coli K1 translocates into the bloodstream by a transcellular route. (
  • Susceptible animals were unable to control E. coli K1 numbers at the site of translocation. (
  • Two thirds of the resistant animals became susceptible to E. coli K1 infection when their antimicrobial peptide (α-defensins) producing Paneth cells were selectively ablated with a chemical reagent, dithizone. (
  • We compared an additive model with combination models in which resistant infections were replaced by susceptible infections. (
  • Recent retrospective data suggest that beta-lactam/beta-lactamase inhibitor combinations, such as piperacillin-tazobactam, may be non-inferior to carbapenems for the treatment of bloodstream infection caused by extended-spectrum beta-lactamase-producers, if susceptible in vitro. (
  • Certain rare or exotic infections, including anthrax , plague , and brucellosis , are also susceptible to tetracyclines. (
  • Significant damage that leads to recurrent infections. (
  • Hyperglycemia causes neutrophil dysfunction by increasing intracellular calcium levels and interfering with actin and, thus, diapedesis and phagocytosis.Associated vaginal candidiasis and vascular disease also play a role in recurrent infections.SGLT2 inhibitors markedly increase glucose excretion by the kidney which may lead to a UTI. (
  • With this new antibody, we open the door for better treatment strategies for patients who suffer from chronic infections associated with implanted medical devices or who suffer from recurrent infections, such as repeated infections of the urinary tract," explained Dr Cagla Tukel, associate professor in the Department of Microbiology and Immunology at LKSOM and senior author on the new study. (
  • Discolored patches of skin are the most noticeable symptom therapy for recurrent infection are major risk factors for what they don't need and changing or adding others. (
  • Urinary tract infections (UTI) are one of the most frequent bacterial infections affecting people both in the community and in hospitals [ 1 ]. (
  • Urinary tract infection: an overview. (
  • Current concepts in the treatment of urinary tract infections and prostatitis. (
  • The fluoroquinolones for urinary tract infections: a review. (
  • We report a lab-on-a-chip (LOC) that can separate and detect Escherichia coli (E. coli) in simulated urine samples for urinary tract infection (UTI) applications. (
  • Therefore, the possibility that infection has ascended to the kidneys must be considered, and treatment regimens must assume that infection of the upper urinary tract has occurred. (
  • the purpose of this study was to assess an optimal strategy for the effective antibiotic treatment of urinary tract infections. (
  • Aetiology of urinary tract infections (UTI) and their antibiotic sensitivity patterns vary from time to time and across different areas. (
  • There is a need for proper surveillance and development of hospital specific antibiograms to inform appropriate empiric therapy of urinary tract infections. (
  • E coli can cause opportunistic infections in any body system (see Table 1 ) but is most commonly involved in urinary tract and skin/soft tissue infections. (
  • It is also sometimes known as a urinary tract infection because the urinary tract includes the bladder, urethra, ureters, and kidneys. (
  • Learn more about urinary tract infections here. (
  • In endogenous endophthalmitis, urinary tract infection was the most common primary site of infection and nearly all patients are diabetic. (
  • Patients with a neurogenic bladder or bladder diverticulum and postmenopausal women with bladder or uterine prolapse have an increased frequency of urinary tract infection because of incomplete bladder emptying. (
  • For more information on this topic, see the Medscape Reference article Urinary Tract Infections in Diabetes Mellitus . (
  • The intramuscular injection is used to treat urinary tract infections caused by Escherichia coli. (
  • Escherichia coli (E. coli) infections are the major health concern, as it causes infections in human mainly in urinary tract, ear, and wound infections. (
  • Catheter-associated urinary tract infections (CAUTI) are the most common hospital-associated infections. (
  • Urinary tract infection (UTI) has been reported most often in recent days. (
  • Improved ultrasound detection of renal scarring in kids following urinary tract an infection. (
  • Do systemic signs predict the chance of kidney scarring after urinary tract infection Does prompt remedy of urinary tract infection in preschool children forestall renal scarring: blended retrospective and prospective audits. (
  • Guidelines to establish abnormalities after childhood urinary tract infections: a potential audit. (
  • Urinary Tract Infection: Diagnosis, Treatment, and Long Term Management of Urinary Tract Infection in Children. (
  • Radiographic evaluation of youngsters with febrile urinary tract infection: bottom-up, top-down, or none of the above Comparative bacteriologic research of urine obtained from youngsters by percutaneous suprapubic aspiration of the bladder and by catheter. (
  • Pregnant women are at increased risk for urinary tract infection (UTI) but in many cases infection is asymptomatic. (
  • In addition, S fimbriae have been associated with many of the E coli of patients with CNS infections. (
  • Moreover, additional factors contributed to decrease the total number of inclusions, including i) the variability of local ecology in burn centres and ii) the fact that while most burn infections are polymicrobial (induced by several bacterial species), our drug products were mono-specific (targeting only one bacterial species), which in many cases prevented their use to treat such infections and therefore to include corresponding patients. (
  • Table 2 Characteristics of ST131 E. coli colonized and non-colonized hospital contacts of index nosocomial patients. (
  • Pulsed-field gel electrophoresis was used to determine the possible horizontal transfer of E. coli among patients . (
  • Findings of ileus may indicate the severity of colitis in patients with C difficile infection. (
  • These infections most commonly occur in patients who are debilitated, immunocompromised, or diabetic or in corneas with an underlying pathologic condition. (
  • Corneal infection due to E coli produce indolent corneal ulcers with poor prognosis because most of these patients of have an underlying immunocompromised disorder or have abnormal corneal surface with compromised protective barrier. (
  • a Treatment of infections due to this organism in the organ system was studied in fewer than 10 patients. (
  • To investigate the microbiological profile of intra-abdominal abscesses drained from patients with Crohn's disease (CD) compared to patients with complicated diverticulitis coli (cDC). (
  • Importantly, fungal infections including Candida albicans may be present in chronic abscesses, especially when patients are immune-suppressed, malnourished, or on protracted courses of antibiotic therapy. (
  • It also draws attention to the fact that uncontrolled diabetes has the propensity to allow for large-scale infections in patients that have no open wounds or obvious sources of infection. (
  • Human infections caused by Acinetobacter species include pneumonia, which is most often related to endotracheal tubes or tracheostomies, endocarditis, meningitis, skin and wound infections, peritonitis in patients receiving peritoneal dialysis, UTI and bacteremia. (
  • The body's immune system reacts to toxins released during an intestinal bacterial infection. (
  • E. coli was isolated from 144 samples (84.2%), of which 90% were resistant to at least one antibiotic and 44% were multi-drug resistant (MDR). (
  • The number of infections caused by resistant organisms is largely unknown. (
  • Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (
  • Linezolid versus vancomycin in the treatment of known or suspected resistant gram-positive infections in neonates. (
  • 3 However, other studies also show an alarming increase in quinolone-resistant E. coli 4 intrinsic third-generation cephalosporin resistant Enterococcus faecium 5 and Candida spp. (
  • These consortiums can colonize a variety of surfaces, such as host tissues, dentures, and catheters, resulting in infections highly resistant to drugs, when compared with their planktonic counterparts. (
  • Bacterial persister cells are dormant cells, tolerant to multiple antibiotics, that are involved in several chronic infections. (
  • Although an uncomplicated bladder infection is often easily treated with a short course of antibiotics , it can be considerably uncomfortable for the person who has it. (
  • Doctors usually treat people with uncomplicated bladder infections with a short course of antibiotics. (
  • Successful treatment of experimental Escherichia coli infections in mice using phage: its general superiority over antibiotics. (
  • Apply a lukewarm compress or take a lukewarm bath antibiotics and decided to try home remedies for sinus infections, still shocked that I agreed to take antibiotics. (
  • It is also one of a group of antibiotics which together may be used to treat peptic ulcers caused by bacterial infections. (
  • Escherichia coli K1 is a major cause of neonatal bacterial meningitis (NBM). (
  • In summary, our study uncovers the involvement of lncC11orf54-1 in IRAK1-NF-κB signaling, and it functions as a positive regulator of inflammatory responses in meningitic E. coli -induced neuroinflammation, which may be a valuable therapeutic and diagnostic target for bacterial meningitis. (
  • Bacterial meningitis is an important life-threatening infection of the central nervous system (CNS), with high morbidity and mortality worldwide. (
  • The prevention of infection requires control measures at all stages of the food chain, from agricultural production on the farm to processing, manufacturing and preparation of foods in both commercial establishments and household kitchens. (
  • Certain lifestyle changes, such as hygiene habits and switching birth control methods may also help in the prevention of bladder infections. (
  • Walmsley RS, David DB, Allan RN, Kirkby GR. Bilateral endogenous Escherichia coli endophthalmitis: a devastating complication in an insulin-dependent diabetic. (
  • Using the neonatal rat model, this study aimed to analyse 1) the spatial distribution of E. coli K1 in the GI tract in an attempt to identify the site of translocation, 2) the role of Paneth cells in E. coli K1 pathogenesis and 3) the possibility of endogenous Trefoil factor 2 (Tff2) feeding as a prophylactic therapy. (
  • Approximately 5-10% of endogenous bacterial endophthalmitis is due to E coli . (
  • E. coli infection caused ileum inflamation as decrease endogenous antioxidant (SOD) and mucosal illleum destroyed. (
  • Most are uncomplicated infections typically caused by the Escherichia coli ( E. coli ) bacterium. (
  • The predominant aerobic and facultative organisms were E. coli and Streptococcus spp. (
  • Vaginal yeast infections can be treated naturally at home externa if you have a condition that can weaken is home to millions of yeast organisms, many of which are considered good as far as our health. (
  • Food poisoning, also called foodborne illness, is an infection or irritation of your digestive tract that spreads through food or drinks. (
  • An estimated 205,800 foodborne cases from all four types of E. coli occur annually in the United States (Scallan et al. (
  • E. coli ATCC 25922 was used as a control. (
  • Pyelonephritis: the relationship between infection, renal scarring and antimicrobial therapy. (
  • The genus Escherichia is named after Theodor Escherich who isolated the type species of the genus in 1885. (